Patient With Transplanted Pig Kidney Leaves Hospital for Home
Richard Slayman, 62, is the first patient to receive a kidney from a genetically modified pig. Two weeks after the procedure, he was well enough to be discharged, doctors said. (Source: NYT Health)
Source: NYT Health - April 4, 2024 Category: Consumer Health News Authors: Roni Caryn Rabin Tags: your-feed-science Kidneys Genetic Engineering Pigs Immune System Transplants Black People Dialysis Surgery and Surgeons Urine Source Type: news
Modern Blackfoot people descend from an ancient ice age lineage
Nations of the Blackfoot Confederacy have long fought to maintain control over their land and water. Oral traditions and archaeological evidence indicate the Blackfoot Indigenous peoples and their ancestors have inhabited a broad swatch of North America for more than 10,000 years.
A study published today in
Science Advances
reinforces that connection. Genetic data confirm
modern Blackfoot people are closely related to those who lived on the land hundreds of years ago
.
The findings also suggest Blackfoot people descend from a previously unknown genetic lineage extending back roughly 18,00...
Source: ScienceNOW - April 3, 2024 Category: Science Source Type: news
Muscle cramp compound may drive deadly wasting in cancer patients
“The flesh is consumed and becomes water … the abdomen fills with water, the feet and legs swell, the shoulders, clavicles, chest, and thighs melt away. … The illness is fatal.”
This spine-chilling description, written by Greek physician and philosopher Hippocrates, is believed to be the first account of a deadly muscle wasting disease called cachexia (pronounced kuh-KEK-sia). Scientists estimate that up to 80% of cancer patients suffer from the condition, where the body relentlessly eats away at itself until organs such as the heart and diaphragm stop working. Even if cachexia doesn’t directly kill a patie...
Source: ScienceNOW - April 3, 2024 Category: Science Source Type: news
Periodontitis and Sjogren ’s syndrome: a bidirectional two-sample mendelian randomization study
ConclusionsNo
genetic causality between PD and SS or vice versa was supported by our
results under MR assumptions and limitations. The study results provided
new insights into the relationship between periodontal status and
sjogren ’s syndrome, highlighting the need for a more prudent medical
intervention. (Source: Dental Technology Blog)
Source: Dental Technology Blog - April 3, 2024 Category: Dentistry Source Type: news
Drug shows promise for slowing progression of rare, painful genetic disease
NIH-supported clinical trial could lead to first effective treatment for ACDC disease. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - April 3, 2024 Category: American Health Source Type: news
A genetically informed longitudinal study of early-life temperament and childhood aggression - Penichet EN, Beam CR, Luczak SE, Davis DW.
The present study examined the longitudinal associations between three dimensions of temperament - activity, affect-extraversion, and task orientation - and childhood aggression. Using 131 monozygotic and 173 dizygotic (86 same-sex) twin pairs from the Lou... (Source: SafetyLit)
Source: SafetyLit - April 3, 2024 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news
Genetic Testing of Some Patients With Early-Onset AF Advised Genetic Testing of Some Patients With Early-Onset AF Advised
Certain genetic variants may underlie atrial fibrillation alone, a ventricular cardiomyopathy or channelopathy syndrome, or both.Medscape Medical News (Source: Medscape FamilyMedicine Headlines)
Source: Medscape FamilyMedicine Headlines - April 3, 2024 Category: Primary Care Tags: Cardiology Source Type: news
Smartphone app could help detect early-onset dementia cause, study finds
App-based cognitive tests found to be proficient at detecting frontotemporal dementia in those most at riskA smartphone app could help detect a leading cause of early-onset dementia in people who are at high risk of developing it, data suggests.Scientists have demonstrated that cognitive tests done via a smartphone app are at least as sensitive at detecting early signsof frontotemporal dementia in people with a genetic predisposition to the condition as medical evaluations performed in clinics.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - April 1, 2024 Category: Science Authors: Linda Geddes Science correspondent Tags: Dementia Apps Smartphones Health Technology Society Mental health Science Medical research Neuroscience Source Type: news
Optimization of horizontal road alignment based on parameters affecting its cost and lifespan using genetic algorithm - Aftabi Hossein S, Rahimov K.
This paper presents an approach for the optimization of horizontal road alignment with a focus on parameters affecting its cost and lifespan. The study area is the Bandar-e Anzali 16Km bypass highway, situated in north Iran, which holds significant economi... (Source: SafetyLit)
Source: SafetyLit - April 1, 2024 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Associations between polygenic liability to psychopathology and non-suicidal versus suicidal self-injury - Edwards AC, Singh M, Peterson RE, Webb BT, Gentry AE.
Little is known about how non-suicidal and suicidal self-injury are differentially genetically related to psychopathology and related measures. This research was conducted using the UK Biobank Resource, in participants of European ancestry (N = 2320 non-su... (Source: SafetyLit)
Source: SafetyLit - April 1, 2024 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
Scientist who gene-edited babies is back in lab and ‘proud’ of past work despite jailing
China ’s He Jiankui, who used Crispr to edit genome, says he is working on genetic diseases and suggests human embryo gene editing will one day be acceptedA Chinese scientist who wasimprisoned for his role in creating the world ’s first genetically edited babies says he has returned to his laboratory to work on the treatment of Alzheimer’s and other genetic diseases.In aninterview with a Japanese newspaper, He Jiankui said he had resumed research on human embryo genome editing, despite the controversy over the ethics of artificially rewriting genes, which some critics predicted would lead to demand for “designer ba...
Source: Guardian Unlimited Science - April 1, 2024 Category: Science Authors: Justin McCurry in Osaka Tags: Genetics Biology Science World news China Source Type: news
Personal journey shapes unique perspective
Dr. Hasadsri and their sons Silas and Paul enjoy a ride at Disneyland this past fall. When Linda Hasadsri, M.D., Ph.D. (they/them/she/her), began a Mayo Clinic fellowship in Clinical Molecular Genetics immediately after completing their training in Clinical Biochemical Genetics, they never imagined the genetic tests they were helping develop would be the very same tests that guided the ir life’s journey. But just after starting that fellowship, Dr. Hasadsri’s personal and professional worlds collided, giving them a… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - March 31, 2024 Category: Databases & Libraries Source Type: news
More Physical Activity Needed to Cut Risk for Obesity Among Those With Genetic Risk
FRIDAY, March 29, 2024 -- The daily step count needed to reduce the risk for obesity varies based on an individual ' s genetic risk for higher body mass index (BMI), according to a study published online March 27 in JAMA Network Open.Evan L.... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 29, 2024 Category: Pharmaceuticals Source Type: news
Mutation Helps Even Carriers of'Alzheimer's Gene' Avoid Alzheimer's
FRIDAY, March 29, 2024 -- A genetic mutation that boosts cell function could protect people against Alzheimer ’s disease, even if they carry another gene mutation known to boost dementia risk.The newly discovered mutation appears to protect people... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - March 29, 2024 Category: General Medicine Source Type: news
Weight loss biotech plans IPO as demand builds for anti-obesity treatments
Aardvark Therapeutics’ drug has been shown in trials to suppress cravings in patients with rare genetic form of obesity (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - March 29, 2024 Category: Pharmaceuticals Source Type: news
