US Surgeons Perform First Pig-to-human Kidney Transplant US Surgeons Perform First Pig-to-human Kidney Transplant
A 62-year-man with end-stage renal disease has become the first human to receive a new kidney from a genetically modified pig, doctors from Massachusetts General Hospital in...Reuters Health Information (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 21, 2024 Category: Consumer Health News Tags: Nephrology Source Type: news
Surgeons Transplant Pig Kidney Into a Patient, a Medical Milestone
The man continues to improve, doctors said. Organs from genetically engineered pigs one day may make dialysis obsolete. (Source: NYT Health)
Source: NYT Health - March 21, 2024 Category: Consumer Health News Authors: Roni Caryn Rabin Tags: your-feed-science Kidneys Genetic Engineering Pigs Surgery and Surgeons Immune System Doctors Cloning Diabetes Black People Urine Blood Massachusetts General Hospital Boston (Mass) Source Type: news
The World ’s Most Expensive Drug Is Now a $4.25 Million Gene Therapy
A new gene therapy for an ultra-rare disease will have a wholesale cost of $4.25 million, making it the world’s most expensive drug.
The one-time treatment, Lenmeldy, won U.S. regulatory approval on Monday to correct the underlying cause of a hereditary condition called early-onset metachromatic leukodystrophy, or MLD.
MLD is a fatal disease in which infants sometimes start to lose the ability to walk and talk. Orchard Therapeutics said the drug’s price “reflects its clinical, economic and societal value” in a statement Wednesday.
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Source: TIME: Health - March 21, 2024 Category: Consumer Health News Authors: Gerry Smith/Bloomberg Tags: Uncategorized healthscienceclimate wire Source Type: news
Gene Variants May Modify Diet-Attributable CRC Risk Gene Variants May Modify Diet-Attributable CRC Risk
Researchers sought to identify the genetic factors that may contribute to higher CRC risk with intake of red meat, processed meat, and alcohol and lower risk with frequent fruit consumption.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - March 21, 2024 Category: Gastroenterology Tags: Gastroenterology Source Type: news
First-Ever Pig Kidney Transplant Performed in Living Recipient
(MedPage Today) -- A 62-year-old man with end-stage kidney disease (ESKD) received the world's first successful transplant of a genetically edited pig kidney, doctors in Boston announced.
The 4-hour surgery took place on March 16 at the Mass General... (Source: MedPage Today Surgery)
Source: MedPage Today Surgery - March 21, 2024 Category: Surgery Source Type: news
Pressure grows to ditch controversial forced swim test in rodent studies of depression
For the past few decades, scientists studying candidate antidepressant drugs have had a convenient animal test: how long a rodent dropped in water keeps swimming.
Invented in 1977
, the forced swim test (FST) hinged on the idea that a depressed animal would give up quickly. It seemed to work: Antidepressants and electroconvulsive therapy often made the animal try harder. The test remains popular,
appearing in about 600 papers per year
.
But researchers have recently begun to question the assumption that the test really gauges depression and is a good predictor of human responses to drugs. Oppositi...
Source: ScienceNOW - March 20, 2024 Category: Science Source Type: news
Mutation Linked to Increased Risk of Prostate Cancer Mortality
(MedPage Today) -- The risk of dying of prostate cancer doubled in the presence of a genetic mutation affecting testosterone production, a large prospective cohort study showed.
The 5-year risk of prostate cancer-specific mortality (PCSM) increased... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 20, 2024 Category: Hematology Source Type: news
Positive Causal Link ID'd Between Computer Use, Erectile Dysfunction
WEDNESDAY, March 20, 2024 -- A higher genetic susceptibility to leisure computer usage is associated with an increased risk for erectile dysfunction (ED), according to a study published online March 20 in Andrology.
Zhao Huangfu, from Changhai... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 20, 2024 Category: Pharmaceuticals Source Type: news
Rare genetic disease therapy becomes world’s most expensive drug at $4.25mn
Lenmeldy gene therapy treats MLD, a condition that attacks the central nervous system of young children (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - March 20, 2024 Category: Pharmaceuticals Source Type: news
Scientists to investigate why cystic fibrosis sufferers at greater risk of bowel cancer
Cystic Fibrosis Trust launch an urgent fundraising plea to probe the alarmingly increased risks between the cruel genetic condition, diabetes and bowel cancer. (Source: Daily Express - Health)
Source: Daily Express - Health - March 20, 2024 Category: Consumer Health News Source Type: news
Get to know Harvard geneticist George Church, who's helping a Dallas co. try to revive woolly mammoths
George Church is a legend in Boston's life sciences industry. Now he's helping Dallas-based Colossal work on huge projects including plans to bring back woolly mammoths and other extinct animals. Boston Business Journal recently sat down with this scientific pioneer to discuss his favorite startups, why he prefers to be a co-founder and not a CEO, how woolly mammoths could help fight climate change and more. (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - March 20, 2024 Category: Pharmaceuticals Authors: Hannah Green Source Type: news
HIV cure breakthrough as scientists find way of eliminating AIDS-causing virus
Using 'genetic scissors', researchers at Amsterdam UMC, the Netherlands, were able to snip out the virus from infected T cells in the laboratory, removing all traces. (Source: the Mail online | Health)
Source: the Mail online | Health - March 19, 2024 Category: Consumer Health News Source Type: news
Craving snacks after a meal? It might be food-seeking neurons, not an overactive appetite
Key takeawaysA new study from UCLA researchers is the first to discover food-seeking cells in a part of a mouse ’s brain usually associated with panic – but not with feeding.Activating a selective cluster of these cells kicked mice into “hot pursuit” of live and non-prey food, and showed a craving for fatty foods intense enough that the mice endured foot shocks to get them, something full mice normally would not do.If true in humans, who also carry these cells, the findings could help address the circuit that can circumvent the normal hunger pressures of “how, what and when to eat.”People who find themselves ru...
Source: UCLA Newsroom: Health Sciences - March 19, 2024 Category: Universities & Medical Training Source Type: news
Upstate pulmonologist awarded $1 million NIH grant to unlock genetic secrets of COPD resistance and vulnerability, potentially paving the way for breakthrough treatments
Auyon Ghosh will analyze data of more than 60,000 patients studying genetic factors that contribute to disease risk; study will also address genetic factors that may protect those at risk from developing COPD (Source: SUNY Upstate Medical)
Source: SUNY Upstate Medical - March 19, 2024 Category: Universities & Medical Training Tags: News Source Type: news
Neurologic Genetic Testing Is Less Likely in Black Patients Neurologic Genetic Testing Is Less Likely in Black Patients
Investigators found significant Black patients are significantly less likely than their White counterparts to receive genetic testing for neurologic disorders, new research shows.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - March 19, 2024 Category: Neurology Tags: Neurology & Neurosurgery Source Type: news
