FDA OKs Gamifant, First Drug for Rare Immune Disease HLH FDA OKs Gamifant, First Drug for Rare Immune Disease HLH
Emapalumab is an interferon gamma-blocking antibody that fills an unmet medical need for patients with primary hemophagocytic lymphohistiocytosis, the FDA says.FDA Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 20, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Alert Source Type: news

Critical Isotope for Thyroid Cancer Now Produced in the US Critical Isotope for Thyroid Cancer Now Produced in the US
For the first time in 30 years, iodine-131, a critical radioisotope used for diagnosing and treating thyroid cancer and hyperthyroidism, is being produced in the US.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 20, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Social Isolation Directly Affects Health, Ups Risk of Death Social Isolation Directly Affects Health, Ups Risk of Death
Social isolation predicts all-cause and cardiovascular disease mortality in both sexes and in blacks and whites, and also predicts cancer-related mortality in white men and women.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 20, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

' Outsider' Oncologist Whistleblowers Share in $100M Reward'Outsider' Oncologist Whistleblowers Share in $100M Reward
One of the largest-ever False Claims Act settlements involved the oncology practice at a multispecialty group in Florida, which is splitting a huge pot of reward money with two other whistleblower lawsuit parties.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 20, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Checkpoint Inhibition and Cardiotoxicity: Cause for Concern? Checkpoint Inhibition and Cardiotoxicity: Cause for Concern?
A pharmacovigilance study reports four new cardiotoxicities in patients treated with immune checkpoint inhibitors. Experts say this should not deter physicians from offering these treatments to patients.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 20, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Cancer Pain Control App Works -- Palliative Care for Everyone? Cancer Pain Control App Works -- Palliative Care for Everyone?
Dramatically improved artificial intelligence holds promise for making palliative care services available anywhere, anytime for patients with advanced cancer pain.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 20, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Single-Visit Cervical Screening Strategy Picks Up Suspect Lesions Single-Visit Cervical Screening Strategy Picks Up Suspect Lesions
A single-visit cervical cancer screening strategy, trialed in a low-income setting in China, maximizes detection rates and minimizes loss to follow-up at a very low cost of $6 per test.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 19, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Physician, Know Thyself When Communicating With Cancer Patients Physician, Know Thyself When Communicating With Cancer Patients
At the third consensus meeting for communication skills in Europe, experts recommended that physicians consider each patient to be unique and that they look inward to examine their own feelings about cancer.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 19, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Immunotherapy Adverse Events More Common Than Initially Reported Immunotherapy Adverse Events More Common Than Initially Reported
The rate of immunotherapy adverse events, as evidenced in real world data, is much higher than was previously reported in the pivotal clinical trials of these agents.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 19, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

TNM Staging 8th Edition and Its Implications for Skin Cancer TNM Staging 8th Edition and Its Implications for Skin Cancer
This article summarizes important changes in the 8th edition of TNM that impact the staging, risk stratification, and management of melanoma and nonmelanoma skin cancer.The British Journal of Dermatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 19, 2018 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

DNA-Repair-Gene Mutations Linked to More Aggressive Prostate Cancer DNA-Repair-Gene Mutations Linked to More Aggressive Prostate Cancer
Germline mutations in three DNA-repair genes (ATM and BRCA1/2) are associated with a greater likelihood of grade reclassification in men on active surveillance (AS) for prostate cancer, researchers report.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 18, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Managing CAR T-Cell Therapy in Patients With Hematologic Malignancies
Stephanie Jackson, MSN, RN speaks withCancer Network about the role oncology nurses play in managing patients with hematologic malignancies who are undergoing CAR T-cell therapy. (Source: CancerNetwork)
Source: CancerNetwork - November 16, 2018 Category: Cancer & Oncology Authors: Stephanie Jackson, MSN, RN Source Type: news

Approval in 2 Weeks via FDA's New Oncology Drugs Review Approval in 2 Weeks via FDA's New Oncology Drugs Review
Approval of a new indication took only 2 weeks with the FDA's new program for reviewing oncology drugs. It involved expanded use of the lymphoma drug brentuximab vedotin.FDA Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 16, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Alert Source Type: news

EU Changes Mind on Nivo Plus Ipi for Kidney Cancer EU Changes Mind on Nivo Plus Ipi for Kidney Cancer
Positive opinions were given for the first-line use of the immunotherapy combination nivolumab and ipilimumab in kidney cancer and for an extension of indication for blinatumomab in certain leukemia patients.International Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 16, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Alert Source Type: news

Lung Cancer Advances: A Year Like No Other Lung Cancer Advances: A Year Like No Other
2018 has been a year of extraordinary advances in lung cancer treatment.Medscape Oncology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 16, 2018 Category: Consumer Health News Tags: Hematology-Oncology Commentary Source Type: news

EU Green Light for Apalutamide for Nonmetastatic CRPC EU Green Light for Apalutamide for Nonmetastatic CRPC
The next-generation antiandrogen has received a positive opinion for nonmetatatic castration-resistant prostate cancer (CRPC), considered to be an unmet medical need.International Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 16, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Alert Source Type: news

EU Green Lights Apalutamide for Nonmetastatic CRPC EU Green Lights Apalutamide for Nonmetastatic CRPC
The next-generation antiandrogen has received a positive opinion for nonmetatatic castration-resistant prostate cancer (CRPC), considered to be an unmet medical need.International Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 16, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Alert Source Type: news

Kerr, Tannock on the'Triangle of Mediocrity' Holding Oncology Back Kerr, Tannock on the'Triangle of Mediocrity' Holding Oncology Back
With nearly 75 years of oncology experience between them, Drs Kerr and Tannock take aim at the pitfalls of precision medicine and the'triangle of mediocrity'among academic medicine, pharma companies, and the FDA.Medscape Oncology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 16, 2018 Category: Consumer Health News Tags: Hematology-Oncology Commentary Source Type: news

Medical News Today: What to know about ferritin blood tests for anemia
A ferritin blood test is a simple way to check a person's iron levels. In this article, we discuss normal, low, and high levels, what they mean, and how to alter blood ferritin levels. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 16, 2018 Category: Consumer Health News Tags: Blood / Hematology Source Type: news

Insurer Faces $25.5m Payout After Denial of Proton Therapy Insurer Faces $25.5m Payout After Denial of Proton Therapy
Health insurer Aetna denied proton therapy because it was'experimental.'This jury verdict raises the possibility that other denial-of-care suits will follow.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 16, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Cytomorphometric Neutrophil and Monocyte Markers May Strengthen the Diagnosis of Sepsis
The authors of this research article state that the diagnosis of sepsis is challenging in the absence of a gold standard test. Recent studies have explored the role of neutrophil and monocyte volume, conductivity, and scatter (VCS), derived from automated hematology analyzers, in diagnosing sepsis. The authors assessed the diagnostic accuracy of VCS parameters in critically ill patients with sepsis. They say that in critically ill patients with suspected sepsis, VCS parameters may help strengthen the diagnostic probability of sepsis. Future studies may explore the role of serial monitoring of VCS to track response to antim...
Source: Current Awareness Service for Health (CASH) - November 16, 2018 Category: Consumer Health News Source Type: news

Medical News Today: Hemophilia, coagulation, and blood clotting
If blood does not clot, life-threatening bleeding can occcur. Find out about how blood clots, how clotting factors work, and how treatment has improved the outlook for people with hemophilia. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 16, 2018 Category: Consumer Health News Tags: Blood / Hematology Source Type: news

New research on CAR T cell therapy, bone marrow transplants and blood cancer treatments
(City of Hope) City of Hope announced today that it will present data on new findings on immunotherapies, including CAR T cell therapy, bone marrow transplants and other treatments for blood cancers, at the American Society of Hematology (ASH) Annual Meeting Dec. 1-4 in San Diego. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 16, 2018 Category: Cancer & Oncology Source Type: news

Roche's Tecentriq Wins Fast FDA Review in Tough-to-Treat Breast Cancer Roche's Tecentriq Wins Fast FDA Review in Tough-to-Treat Breast Cancer
Swiss drugmaker Roche said on Tuesday its Tecentriq medicine will get a speedy review by U.S. regulators in a tough-to-treat form of breast cancer, as it seeks to be the first company to have its immunotherapy win approval in this indication.Reuters Health Information (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 15, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

MSI CRC Not Responding to Immunotherapy: Is it Misdiagnosis? MSI CRC Not Responding to Immunotherapy: Is it Misdiagnosis?
Patients with MSI-H tumors who do not initially respond to immunotherapy are presumed to have primary resistance. But there is the tantalizing possibility that they may have been misdiagnosed.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 15, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Increasing Tumor Stage Predicts Local Regrowth of Rectal Cancer During Watch-and-Wait Management Increasing Tumor Stage Predicts Local Regrowth of Rectal Cancer During Watch-and-Wait Management
Increasing tumor stage is associated with greater risk of rectal-cancer local regrowth in patients with a clinical complete response following chemoradiotherapy who are managed by watch-and-wait, according to a new meta-analysis.Reuters Health Information (Source: Medscape Radiology Headlines)
Source: Medscape Radiology Headlines - November 15, 2018 Category: Radiology Tags: Hematology-Oncology News Source Type: news

' Shocking' Results With Minimally Invasive Hysterectomy'Shocking' Results With Minimally Invasive Hysterectomy
The surprising results of two new studies prompt a warning from Dr Maurie Markman that minimally invasive radical hysterectomy should not be considered standard of care for early cervical cancer.Medscape Oncology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 15, 2018 Category: Consumer Health News Tags: Hematology-Oncology Commentary Source Type: news

Teenage Obesity & Fourfold Increase in Risk for Pancreatic Cancer Teenage Obesity & Fourfold Increase in Risk for Pancreatic Cancer
Data linking two large Israeli databases suggest that obesity during teenage years increases the risk for adult pancreatic cancer fourfold. Being overweight increases the risk twofold.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 15, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Duke University Hospital seeking $18.2M renovation
Duke University Health System is asking the state of North Carolina for permission to begin an $18.2 million overhaul on part of its main campus.   This week, the N.C. Department of Health and Human Services released an application petitioning for a certificate of need that would allow for the renovations at Duke University Hospital.  According to NCDHHS, the project would renovate the north pavilion at the hospital for the system’s adu lt bone marrow transplant services and a combined hematologic… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - November 15, 2018 Category: Biotechnology Authors: Seth Gulledge Source Type: news

Downplaying Drug Toxicity in Oncology Clinical Trials Downplaying Drug Toxicity in Oncology Clinical Trials
Incomplete reporting that downplayed drug-related adverse events was identified in 43% of reports of cancer drug trials published by top medical journals.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 15, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Metastasis in Patients With Hepatocellular Carcinoma Metastasis in Patients With Hepatocellular Carcinoma
This authors investigated the prevalence, associated factors, and prognostic impact of metastasis in hepatocellular carcinoma, proposing a modified BCLC system based on metastasis.Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 15, 2018 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

New Pathway to Bone Metastasis Opens Door to Blockade New Pathway to Bone Metastasis Opens Door to Blockade
Intricate pathway through which cancer cells likely spread to bone now opens the door to its pharmaceutical blockade and potentially mitigate against metastatic disease progression.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 14, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Chemo-Radiation for Distant Mets Ups Survival in Anal Cancer Chemo-Radiation for Distant Mets Ups Survival in Anal Cancer
Extended-field chemo-radiation therapy should be considered a potentially curative treatment option for some patients with advanced anal cancer.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 14, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Fecal Transplant May Resolve Immunotherapy-Related Colitis Fecal Transplant May Resolve Immunotherapy-Related Colitis
Colitis associated with the use of checkpoint inhibitors may be managed successfully by fecal microbiota transplant, says a team reporting results in two patients.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 14, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Electrophysiological measure of impaired information processing in drivers with hematological malignancy - Anderson DE, Bhatt VR, Schmid K, Lunning M, Holstein SA, Rizzo M.
The broad goal of this study is to measure remote effects of cancer on brain physiology and behaviors that underpin instrumental activities of daily living such as automobile driving. Studies of hematological malignancies (HM) have demonstrated impairments... (Source: SafetyLit)
Source: SafetyLit - November 14, 2018 Category: International Medicine & Public Health Tags: Distraction, Fatigue, Chronobiology, Vigilance, Workload Source Type: news

Pemphigus Vulgaris as Manifestation of Multiple Myeloma Pemphigus Vulgaris as Manifestation of Multiple Myeloma
This case illustrates an uncommon occurrence of multiple myeloma initially presenting with pemphigus vulgaris.Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 14, 2018 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

Immune Combo Active in Relapsed/Refractory AML
(MedPage Today) -- Response, survival with nivolumab and azacitidine top historical data (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - November 14, 2018 Category: Hematology Source Type: news

App Cuts Cancer Pain; Immune Tx Side Effects; Gaps in Goals of Care
(MedPage Today) -- Highlights from the Palliative and Supportive Care in Oncology Symposium (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - November 13, 2018 Category: Hematology Source Type: news

AMA Urges Coverage for Added Breast Cancer Screening
(MedPage Today) -- Resolution aimed at women with dense breasts (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - November 13, 2018 Category: Hematology Source Type: news

At ESMO, New Data on Managing Long-term Immunotherapy Responders At ESMO, New Data on Managing Long-term Immunotherapy Responders
Despite closely following the 2018 World Conference on Lung Cancer, this year's annual congress of the European Society for Medical Oncology offered important immunotherapy data in lung cancer.Medscape Oncology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 13, 2018 Category: Consumer Health News Tags: Hematology-Oncology Commentary Source Type: news

Simple Ovarian Cysts on Ultrasound Need No Further Monitoring Simple Ovarian Cysts on Ultrasound Need No Further Monitoring
Simple ovarian cysts discovered on ultrasound are not associated with an increased risk for ovarian cancer and do not need further follow-up imaging, say researchers.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 12, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Simple Ovarian Cysts Hold No Cancer Risk
(MedPage Today) -- Malignancy extremely rare, don't need surveillance (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - November 12, 2018 Category: Hematology Source Type: news

Strategies to Combat the Crises of Opioid Scarcity and Abuse Strategies to Combat the Crises of Opioid Scarcity and Abuse
Three suggestions are provided for combating the co-occurring crises of opioid shortage and abuse.Journal of Clinical Oncology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 12, 2018 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

Biochemical Recurrence Predicts Prostate-Cancer Survival in Some Biochemical Recurrence Predicts Prostate-Cancer Survival in Some
Biochemical recurrence predicts survival in men with prostate cancer who have additional specific clinical risk factors, according to a systematic review.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - November 12, 2018 Category: Pathology Tags: Hematology-Oncology News Source Type: news

Age Just a Number for Older, Fit Limited-Stage SCLC Patients
(MedPage Today) -- Standard chemoradiotherapy proved just as effective compared with younger patients (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - November 9, 2018 Category: Hematology Source Type: news

No Cosmetic Difference With Hypofractionated WBI in Breast Ca
(MedPage Today) -- Equivalent to conventionally fractionated approach in early-stage disease (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - November 9, 2018 Category: Hematology Source Type: news

Arti Hurria, MD,'Giant' in Geriatric Oncology, Dies in Accident Arti Hurria, MD,'Giant' in Geriatric Oncology, Dies in Accident
Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 9, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

ThyroSeq Test Helps Avoid Unnecessary Thyroid Surgeries ThyroSeq Test Helps Avoid Unnecessary Thyroid Surgeries
The multigene molecular classifier ThyroSeq shows high sensitivity, specificity, and detailed genetic profiles, allowing fewer unnecessary diagnostic surgeries for indeterminate thyroid nodules.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 9, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Efficacy of Trabectedin in Elderly Patients With Sarcoma Efficacy of Trabectedin in Elderly Patients With Sarcoma
Elderly patients with good performance status benefit from trabectedin for soft tissue sarcoma similarly to younger patients.Annals of Oncology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 9, 2018 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

Kathy Miller on IMpassion130: New Standard? Not Yet Kathy Miller on IMpassion130: New Standard? Not Yet
New standard of care? Not so fast, says Kathy Miller.Medscape Oncology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 8, 2018 Category: Consumer Health News Tags: Hematology-Oncology Commentary Source Type: news