CCR Grand Rounds: New Frontiers of Cancer Cell and Gene Therapy: Is the Future Now?
CCR Grand Rounds Hosted by the CCR Office of Equity& Inclusion “ New Frontiers of Cancer Cell and Gene Therapy: Is the Future Now? ” Rayne H. Rouce, M.D.Associate Professor, Department of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine Associate Director, Community Engagement, Office of Diversity, Baylor College of Medicine Friday, May 17, 202412:00 – 1:00 p.m.Lipsett AmphitheaterDr. Rayne Rouce is a physician at Texas Children's Cancer Center where she is a member of the Bone Marrow Transplant/Stem Cell Transplant Program. Her clinical time is spen...
Source: Videocast - All Events - May 6, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video
CCR Grand Rounds: Lentiviral Gene Therapy for Blood Disorders: Wiskott-Aldrich Syndrome
CCR Grand Rounds “ Lentiviral Gene Therapy for Blood Disorders: Wiskott-Aldrich Syndrome ” Sung-Yun Pai, M.D.Chief and Senior Investigator Immune Deficiency Cellular Therapy ProgramCenter for Cancer Research, NCIFriday, May 10, 202412:00 – 1:00 p.m.Lipsett AmphitheaterAlso available to view via NIH Videocast.Dr. Sung-Yun Pai received her M.D. degree from Harvard Medical School where she worked in the laboratory of Dr. Barbara Bierer on the cellular biology of calcineurin and mechanism of action of cyclosporine, tacrolimus, and sirolimus. She trained in pediatrics at Boston Children ’ s Hospital and pediatric hemato...
Source: Videocast - All Events - May 6, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video
" Fireside Chat with the Honorable Louis W. Sullivan, M.D. "
In 1989, President George H.W. Bush appointed Louis Wade Sullivan, M.D. secretary of HHS, where he would develop several initiatives to increase racial, ethnic and gender diversity. He oversaw the formation of NIH ’ s Office of Minority Health, later to become NIMHD. He also oversaw the appointment of NIH ’ s first female director, the late Dr. Bernadine Healy, as well as the first female and Hispanic surgeon general and first female HHS chief of staff. This personal and interactive discussion will allow NIH ’ s audience to gain insights through the Honorable Louis W. Sullivan ’ s personal stories and thoughts on v...
Source: Videocast - All Events - March 28, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video
Trade-off Resiliencies, Competing Disease Risks, and Ageotypes Virtual Workshop (Day 2)
Age is the primary risk factor for most major medical conditions, such as cardiovascular diseases (CVD), cancer, diabetes, and neurodegenerative diseases. Aging, disease development, respectively resilience, are thus interconnected, but the molecular pathways and cellular mechanisms involved are not well understood. Deep multi-omics profiling appears to distinguish four molecular patterns of aging in individuals, “ ageotypes, ” that may be connected to competing risk of age-associated diseases. Recent research indicates that development of CVD or cancer are perhaps due to trade-offs between certain genes and processes,...
Source: Videocast - All Events - July 17, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Trade-off Resiliencies, Competing Disease Risks, and Ageotypes Virtual Workshop (Day 1)
Age is the primary risk factor for most major medical conditions, such as cardiovascular diseases (CVD), cancer, diabetes, and neurodegenerative diseases. Aging, disease development, respectively resilience, are thus interconnected, but the molecular pathways and cellular mechanisms involved are not well understood. Deep multi-omics profiling appears to distinguish four molecular patterns of aging in individuals, “ ageotypes, ” that may be connected to competing risk of age-associated diseases. Recent research indicates that development of CVD or cancer are perhaps due to trade-offs between certain genes and processes,...
Source: Videocast - All Events - July 17, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
NHLBI Reproductive Health in Women and Girls with SCD: Gaps to Solutions (Day 2)
Sickle cell disease (SCD) complicates reproductive health for affected individuals. Girls and women with SCD confront challenges associated with menstruation, contraception, infertility risks, and high-risk pregnancy. This workshop assumes a lifespan approach to reproductive health in people with ovaries and sickle cell disease and engages questions related to pathophysiology, clinical care, and structural disparities that need to be addressed to fulfill the promise of high quality, individualized, comprehensive care for girls and women with SCD.
During the workshop ’ s first day, the major themes will be ovarian reser...
Source: Videocast - All Events - April 17, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
NHLBI Reproductive Health in Women and Girls with SCD: Gaps to Solutions (Day 1)
Sickle cell disease (SCD) complicates reproductive health for affected individuals. Girls and women with SCD confront challenges associated with menstruation, contraception, infertility risks, and high-risk pregnancy. This workshop assumes a lifespan approach to reproductive health in people with ovaries and sickle cell disease and engages questions related to pathophysiology, clinical care, and structural disparities that need to be addressed to fulfill the promise of high quality, individualized, comprehensive care for girls and women with SCD.
During the workshop ’ s first day, the major themes will be ovarian reser...
Source: Videocast - All Events - April 17, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Anita Roberts Lecture - Advancing the Development of Effective Therapies for Children and Adults with Rare Tumors
Anita Roberts Lecture 2022
The “ Distinguished Women Scientists at NIH ” lecture series highlights the outstanding research achievements of woman scientists in the NIH Intramural Research Program. This seminar is dedicated to Dr. Anita Roberts and honors her role as an exceptional mentor and scientist.
Dr. Widemann is the Chief of the Pediatric Oncology Branch at NCI where she oversees basic, translational, and clinical research programs for children and young adults with hematologic and solid malignancies. Her research has been focused on drug development and early clinical trials for children with refractory solid tu...
Source: Videocast - All Events - September 26, 2022 Category: General Medicine Tags: Upcoming Events Source Type: video
Hematology from the Ground-Up: Lessons from Bloodless Worms
WALS talkFor more information go tohttps://oir.nih.gov/walsAir date: 11/16/2022 2:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - August 11, 2022 Category: General Medicine Tags: Upcoming Events Source Type: video
Clinical Center Grand Rounds - 3
Predisposition to Myeloid Malignancy
Katherine R. Calvo, MD PhD
Hematopathologist and Senior Research Physician
Director of Automated Hematology and Chimerism Testing,
Department of Laboratory Medicine, CCFor more information go tohttps://clinicalcenter.nih.gov/about/news/grcurrent.htmlAir date: 1/19/2022 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - December 23, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
Lasker Scholar lecture: Cell Therapy for Epithelial Cancers
Lasker Scholar lecture
Cell therapy is an emerging treatment modality that is highly effective in hematological cancers. Research by Dr. Hinrichs ’ s team has demonstrated the potential to extend cell therapy to the treatment of common epithelial cancers. Treatment of patients with human papillomavirus (HPV)-associated cancers with tumor-infiltrating lymphocytes showed durable, complete tumor responses, apparently curing some patients with metastatic cancer. A more “ off the shelf ” approach with peripheral blood T cells genetically engineered to target the HPV E7 antigen also demonstrated robust clinical activity wi...
Source: Videocast - All Events - April 19, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
Cell Therapy for Epithelial Cancers
Cell therapy is an emerging treatment modality that is highly effective in hematological cancers. Research by Dr. Hinrichs ’ s team has demonstrated the potential to extend cell therapy to the treatment of common epithelial cancers. Treatment of patients with human papillomavirus (HPV)-associated cancers with tumor-infiltrating lymphocytes showed durable, complete tumor responses, apparently curing some patients with metastatic cancer. A more “ off the shelf ” approach with peripheral blood T cells genetically engineered to target the HPV E7 antigen also demonstrated robust clinical activity with extensive tumor regr...
Source: Videocast - All Events - February 18, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
Demystifying Medicine - Sickle Cell Anemia: Treatable and/or Curable?
Demystifying Medicine Lecture Series
Although the fundamental molecular pathophysiology of sickle cell anemia was elucidated in studies of this genetic disease starting more than 70 years ago, it is only in about the last two decades that this knowledge has led to specific therapies. Indeed in the last decade serious attention has turned to the possibility of a genetic cure of this condition.
Have we finally cured sickle cell anemia? Not quite, but we may be on the cusp. Really. In a dozen clinical trials planned or underway, some at the NIH Clinical Center, researchers are applying gene therapy to cure this well-studied g...
Source: Videocast - All Events - February 27, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Rear Admiral (Upper Half) Richard W. Childs Flag Promotion Ceremony
The United States Public Health Service Flag Promotion ceremony for Rear Admiral (RADM) Richard W. Childs, promoted to RADM Upper Half O-8 in January 2020, is being webcast live on 3/27/2020 from Masur Auditorium. Richard Childs, MD serves as the Clinical Director of the National Heart, Lung, and Blood Institute (NHLBI) at the National Institutes of Health (NIH). He was commissioned in the USPHS Commissioned Corps as a Lieutenant in 1995 when joined the NCI as an Oncology Fellow. Following fellowship training, he was appointed a tenure-track investigator in the Hematology Branch of the NHLBI where he continues to conduct r...
Source: Videocast - All Events - February 24, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Hereditary Cancer Mutation and Drug Development
NCI ’ s Center for Cancer Research (CCR) Grand Rounds
Dr. Pamela Munster is Co-Director of the Center for BRCA Research, a BRCA-focused clinical and research program at the Helen Diller Family Comprehensive Cancer Center at University of California San Francisco (UCSF). She received her medical degree from the University of Bern, Switzerland; completed her residency in Internal Medicine at Indiana University Medical Center then moved to Memorial Sloan-Kettering Cancer Center, New York for her oncology and hematology fellowship. Dr. Munster served at Memorial Sloan Kettering as a faculty member in the breast cancer progra...
Source: Videocast - All Events - February 3, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
