Abbott launches FlexAbility cath ventricular tachycardia ablation trial
Abbott (NYSE:ABT) said yesterday that it launched a study aiming to evaluate ablation treatments for patients with ventricular tachycardia, touting it as the first such trial of its kind. In the trial, dubbed the Less-VT study, investigators will explore the safety and effectiveness of ablation with the Chicago-area medtech giant’s FlexAbility ablation catheter in treating monomorphic ventricular tachycardia in patients who are unresponsive to drug therapy. “For some patients with sustained monomorphic ventricular tachycardia, drug therapy is an ineffective treatment option. We want to build a body of clin...
Source: Mass Device - November 20, 2018 Category: Medical Devices Authors: Fink Densford Tags: Cardiovascular Catheters Clinical Trials Featured Abbott Source Type: news

Social Isolation Directly Affects Health, Ups Risk of Death Social Isolation Directly Affects Health, Ups Risk of Death
Social isolation predicts all-cause and cardiovascular disease mortality in both sexes and in blacks and whites, and also predicts cancer-related mortality in white men and women.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 20, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Major Bleeding Up With Frailty in Acute MI Patients
TUESDAY, Nov. 20, 2018 -- Frail acute myocardial infarction (AMI) patients are less likely to undergo cardiac catheterization and have an increased risk for bleeding, according to a study published in the Nov. 26 issue of JACC: Cardiovascular... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 20, 2018 Category: Pharmaceuticals Source Type: news

Workplace bullying and violence tied to higher risk of heart problems
(Reuters Health) - People who are bullied or exposed to violence on the job may be more likely to develop cardiovascular disease than individuals who don't deal with these challenges at work, a European study suggests. (Source: Reuters: Health)
Source: Reuters: Health - November 19, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Smartphone STEMI Detection; Sapien 3 Ultra; Novel BP Drug
(MedPage Today) -- Recent developments of interest in cardiovascular medicine (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 19, 2018 Category: Cardiology Source Type: news

New blood pressure guideline could prevent 3 million cardiovascular events over 10 years
(University of Utah Health) In 2017, the American College of Cardiology and the American Heart Association released new blood pressure guidelines, lowering hypertension threshold to 130/80 mm Hg from the previous 140/90 mm Hg. A new study predicts that achieving and maintaining the 2017 guideline blood pressure goals could prevent more than 3 million cardiovascular disease events over 10 years. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 19, 2018 Category: International Medicine & Public Health Source Type: news

Bullying and violence at work increases the risk of cardiovascular disease
(European Society of Cardiology) People who are bullied at work or experience violence at work are at higher risk of heart and brain blood vessel problems, including heart attacks and stroke, according to the largest prospective study to investigate the link, which is published in the European Heart Journal. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 18, 2018 Category: International Medicine & Public Health Source Type: news

Racial discrimination and acute physiological responses among black young adults: the role of racial identity - Volpe VV, Lee DB, Hoggard LS, Rahal D.
PURPOSE: Racial discrimination has long-term consequences for cardiovascular health, potentially by dysregulating acute physiological responses. However, the role of psychological factors that may be protective or increase vulnerability for dysregulated re... (Source: SafetyLit)
Source: SafetyLit - November 17, 2018 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Educating Inpatients on VTE Boosts Prophylaxis Compliance
(MedPage Today) -- Intervention cut refusal rates by nearly half (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 16, 2018 Category: Cardiology Source Type: news

BioCardia Developing Comprehensive Approach to Treat Heart Failure
It can be a bit trick when trying to put BioCardia’s cell therapy for heart failure in one specific category. Is the CardiAmp Cell Therapy a diagnostic, device, or a biologic? Perhaps it’s all of the above. The San Carlos, CA-based company’s president and CEO painted a clearer picture for the technology noting that it could play a significant role when looking at heart failure treatment. “The [CardiAMP Cell Therapy System] is regulated by the agency [FDA] as a combination product via an IDE PMA device pathway,” Peter Altman, BioCardia...
Source: MDDI - November 16, 2018 Category: Medical Devices Authors: Omar Ford Tags: Cardiovascular Business Source Type: news

Medical News Today: What causes lightheadedness?
People who experience lightheadedness feel dizzy or faint. This sensation is particularly common after standing up too quickly. Learn about the other possible causes and treatment options in this article. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 16, 2018 Category: Consumer Health News Tags: Cardiovascular / Cardiology Source Type: news

Mendelian Randomization Studies Confirm Obesity Risks (CME/CE)
(MedPage Today) -- Meta-analysis corroborates link with T2D and CAD (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 16, 2018 Category: Cardiology Source Type: news

Edwards Lifesciences wins CE Mark for Sapien 3 Ultra TAVR
Edwards Lifesciences (NYSE:EW) said today it won CE Mark approval in the European Union for its Sapien 3 Ultra transcatheter aortic valve replacement system intended for patients with severe, symptomatic aortic stenosis. Despite winning a CE Mark, Edwards said that the new valve will not be launched in Germany due to a preliminary injunction from rival Boston Scientific (NYSE:BSX). The company said that “the German court will hold a full hearing on the merits of the dispute” mid-next year, and that it is hopeful it will prevail. The company said it will introduce the Sapien 3 Ultra in the rest of Euro...
Source: Mass Device - November 16, 2018 Category: Medical Devices Authors: Fink Densford Tags: Cardiac Implants Cardiovascular Featured Regulatory/Compliance Replacement Heart Valves Edwards Lifesciences Source Type: news

HeartFlow wins Japanese reimbursement for FFRct analysis
HeartFlow said yesterday that it won reimbursement coverage from the Japanese Ministry of Health, Labor and Welfare for its HeartFlow FFRct fractional flow reserve analysis. The Redwood City, Calif.-based company said that it has already received approval from the Japanese Pharmaceuticals and Medical Devices Agency, and that reimbursement will go into effect beginning on December 1. “When a patient presents with symptoms suggesting CAD, we want to be able to quickly and effectively diagnose patients while reducing the need for unnecessary tests or invasive procedures. In clinical studies, we were able to see fir...
Source: Mass Device - November 15, 2018 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Cardiovascular Featured Imaging Software / IT HeartFlow Source Type: news

American Heart Association, Nov. 10-12
The American Heart Association 2018 Scientific Sessions The annual meeting of the American Heart Association was held from Nov. 10 to 12 in Chicago and attracted more than 20,000 participants from around the world, including cardiovascular... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 15, 2018 Category: Pharmaceuticals Source Type: news

UMN researchers discover important connection between cells in the liver
(University of Minnesota Medical School) University of Minnesota Medical School researchers have made a discovery which could lead to a new way of thinking about how disease pathogenesis in the liver is regulated, which is important for understanding the condition nonalcoholic fatty liver disease (NAFLD), which is incredibly common and growing. It is apparent that about 30 percent of Americans and are at risk to advance to more severe conditions such as nonalcoholic steatohepatitis (NASH), cirrhosis, cardiovascular disease, or even liver cancer. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 15, 2018 Category: International Medicine & Public Health Source Type: news

The gut microbiota at the intersection of diet and human health
Diet affects multiple facets of human health and is inextricably linked to chronic metabolic conditions such as obesity, type 2 diabetes, and cardiovascular disease. Dietary nutrients are essential not only for human health but also for the health and survival of the trillions of microbes that reside within the human intestines. Diet is a key component of the relationship between humans and their microbial residents; gut microbes use ingested nutrients for fundamental biological processes, and the metabolic outputs of those processes may have important impacts on human physiology. Studies in humans and animal models are be...
Source: ScienceNOW - November 15, 2018 Category: Science Authors: Gentile, C. L., Weir, T. L. Tags: Physiology special/review Source Type: news

Migraine with Aura Tied to Higher Afib Risk (CME/CE)
(MedPage Today) -- Could migraine with aura be embolic TIA? (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 14, 2018 Category: Cardiology Source Type: news

AHA: Guidelines Stress Healthy Lifestyle for Lowering Cholesterol
WEDNESDAY, Nov. 14, 2018 -- A healthy lifestyle for lowering cholesterol should be emphasized for reducing cardiovascular risk across the life course, according to a guideline published online Nov. 14 in Circulation to coincide with the annual... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 14, 2018 Category: Pharmaceuticals Source Type: news

Coronary Calcium Predicts Risk in Familial Hypercholesterolemia (CME/CE)
(MedPage Today) -- FH patients with zero CAC had zero events over median 3.7 years (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 14, 2018 Category: Cardiology Source Type: news

Western lifestyle may cause blood pressure to rise with age
Study of remote communities in Venezuelan rainforest sheds fresh light on hypertensionA western lifestyle might be the reason blood pressure tends to rise with age, according to a study of remote tribal communities.Hypertension is a key risk factor for cardiovascular disease, and in many developed countries, including the UK, the likelihood of developing increases with age.More than a quarter of adults in England have high blood pressure, withrecent figures showing the proportion rises to 58% among those aged 65-74.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - November 14, 2018 Category: Science Authors: Nicola Davis Tags: High blood pressure Society Science Health & wellbeing Life and style Ageing Venezuela Americas World news Europe US news Source Type: news

Sudden Cardiac Death Rates Up in Blacks Versus Whites
WEDNESDAY, Nov. 14, 2018 -- Sudden cardiac death (SCD) rates are significantly higher among black adults than white adults without a history of cardiovascular disease, according to a study published in the Nov. 13 issue of the Journal of the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 14, 2018 Category: Pharmaceuticals Source Type: news

ACC Latin America Conference highlights cardiovascular research, practice in region
(American College of Cardiology) The American College of Cardiology will host the ACC Latin America Conference in partnership with the Peruvian Society of Cardiology in Lima, Peru, on November 16-17, 2018, bringing together top experts to review and discuss new, relevant cardiovascular science pertinent to the region. This is the first time the conference will be held in South America. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 14, 2018 Category: International Medicine & Public Health Source Type: news

AHA: Progress on CVD Mortality Is Anything But
(MedPage Today) -- NHLBI seeks to reinvigorate efforts in cardiovascular health (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - November 13, 2018 Category: American Health Source Type: news

High BP in Young Adults a Harbinger of Premature CVD, Death High BP in Young Adults a Harbinger of Premature CVD, Death
Under revised ACC/AHA blood pressure guidelines, more young people now meet criteria for being hypertensive. What does this mean regarding risk for later cardiovascular events?Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 13, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Medtronic backs infant-sized miniature pacer
Medtronic (NYSE:MDT) is collaborating with researchers at the Children’s National Health System to develop a miniature pacemaker intended for use with infants. The prototype version of the device was presented at the American Heart Association’s 2018 Scientific Sessions by Dr. Rohan Kumthekar of the Sheikh Zayed Institute for Pediatric Surgical Innovation, part of the Children’s National Health System. The newly developed miniature pacer is designed to be implanted through a 1 cm incision just below the ribcage, eliminating the need for open-chest surgery, according to a CNHS report. The device is im...
Source: Mass Device - November 13, 2018 Category: Medical Devices Authors: Fink Densford Tags: Cardiac Assist Devices Cardiac Implants Cardiovascular Research & Development Medtronic Source Type: news

Abiomed shares slide despite Impella CP trial success
Abiomed (NSDQ:ABMD) shares fell approximately 13.1% yesterday despite the company announcing positive results from a pilot trial of its Impella CP heart pump that will clear the way for a pivotal that could nearly double the device’s total addressable market. The company announced on Sunday that a pilot study of its Impella CP, used to unload the left ventricle for patients presenting with anterior ST-segment elevation myocardial infarction without cardiogenic shock met its primary endpoints and that it plans to launch a pivotal trial during the second half of next year. Leerink Partner analyst Danielle Antalffy...
Source: Mass Device - November 13, 2018 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Cardiac Assist Devices Cardiovascular Catheters Featured Wall Street Beat Abiomed Source Type: news

High cholesterol: How to cut your risk
CLARE BERRETT explains how this 'silent killer' with no obvious symptoms can often lead to dangerous health complications including heart problems and cardiovascular disease. (Source: Daily Express - Health)
Source: Daily Express - Health - November 13, 2018 Category: Consumer Health News Source Type: news

AHA: Limited Benefit for n-3 Fatty Acids in CVD, Cancer Prevention
TUESDAY, Nov. 13, 2018 -- Omega-3 fatty acids and vitamin D do not significantly reduce major cardiovascular events or cancer incidence, according to two studies published online Nov. 10 in the New England Journal of Medicine to coincide with the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 13, 2018 Category: Pharmaceuticals Source Type: news

AHA: Dapagliflozin Noninferior to Placebo for MACE in T2DM
TUESDAY, Nov. 13, 2018 -- Treatment with dapagliflozin is noninferior to placebo for major adverse cardiovascular events (MACE) among patients with type 2 diabetes with or at risk for atherosclerotic cardiovascular disease, according to a study... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 13, 2018 Category: Pharmaceuticals Source Type: news

Understanding congenital heart defects to prevent them
(University of Houston) Cardiovascular failures are the leading cause of birth defect-related deaths in infants. To understand why congenital heart defects form, a University of Houston biomedical engineer is watching hearts develop with optical equipment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 13, 2018 Category: International Medicine & Public Health Source Type: news

If your diet fails, try again; your heart will thank you
(Purdue University) Risk factors for cardiovascular disease closely track with changes in eating patterns, even only after a month or so. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 13, 2018 Category: International Medicine & Public Health Source Type: news

Pulmonary Embolism: Web Tool IDs Cases Safe for Home Management
(MedPage Today) -- At-home treatment did not hurt outcomes in study (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 12, 2018 Category: Cardiology Source Type: news

AliveCor Heats up Mobile ECG Market with New Data
A research version of AliveCor’s mobile ECG technology could help rapid diagnosis and treatment of heart attacks, according to a study presented at the 2018 American Heart Association’s Scientific Sessions in Chicago. The ST LEUIS International Multicenter Study determined that the Mountain View, CA-based company’s smartphone technology can identify the condition with good correlation and high sensitivity compared to a standard-lead ECG. A total of 204 subjects (age = 60 years, males = 57%, STEMI activation = 45%) were enrolled from 5 international sites. For all interp...
Source: MDDI - November 12, 2018 Category: Medical Devices Authors: Omar Ford Tags: Business Cardiovascular Source Type: news

Abiomed ’s Successful Pilot Study Leads to Pivotal Trial
Abiomed shares were down as much as 17% despite announcing positive data for its Impella CP. The Danvers, MA-based company presented the data from the 50-patient pilot trial at the American Heart Association annual conference in Chicago and said because of the favorable data it would now move to a pivotal trial. The results of the FDA STEMI Door-to-Unloading safety and feasibility randomized controlled trial, show unloading the left ventricle with Impella CP for 30 minutes prior to reperfusion in patients presenting with anterior ST-segment elevation myocardial infarction (STEMI) without cardiogenic shock is safe and feasi...
Source: MDDI - November 12, 2018 Category: Medical Devices Authors: Omar Ford Tags: Business Source Type: news

AHA: Post-CABG Ticagrelor No Better Than Aspirin
(MedPage Today) -- And safety no better with ticagrelor either (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 12, 2018 Category: Cardiology Source Type: news

Move More, Sit Less: Government Issues New Exercise Guidelines
By Arman Azad, CNN (CNN) — If you’re sitting down while reading this, stand up. Guidelines released Monday by the federal government show that most Americans are not getting the exercise they need, costing the health care system over $100 billion each year. The new standards are similar to those released 10 years ago, but the government is scrapping a recommendation that physical activity occur in 10-minute blocks, instead telling Americans to “move more and sit less” whenever possible. Any amount of exercise has some health benefits, officials say, and some benefits are even immediate, like better ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - November 12, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Exercise Source Type: news

Genetic factors link Alzheimer's, cardiovascular disease, study says
The largest study ever of genetic Alzheimer's disease has linked heart disease and dementia, suggesting that controlling heart disease could delay dementia. (Source: Health News - UPI.com)
Source: Health News - UPI.com - November 12, 2018 Category: Consumer Health News Source Type: news

AHA: Closing Dialysis Fistula Improves Heart Function
(MedPage Today) -- Kidney transplant patients may benefit from reversing arteriovenous connection (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 12, 2018 Category: Cardiology Source Type: news

Subclinical Heart Inflammation Seen in RA (CME/CE)
(MedPage Today) -- Correlated with disease activity (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 12, 2018 Category: Cardiology Source Type: news

AHA: Computer Nudge Gets More Afib Patients on Anticoagulants
(MedPage Today) -- EHR popups triple the number put on medications -- but many still go untreated (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 12, 2018 Category: Cardiology Source Type: news

Medical News Today: Vitamin D, fish oil supplements of little benefit to heart health
Two large new clinical trials have examined the benefits of vitamin D and fish oil supplements for staving off heart disease and cancer. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 12, 2018 Category: Consumer Health News Tags: Cardiovascular / Cardiology Source Type: news

Medical News Today: Chronic noise can impact heart health
New research has investigated the impact of noise on health, and regular exposure to excessive noise appears to increase cardiovascular risk. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 12, 2018 Category: Consumer Health News Tags: Cardiovascular / Cardiology Source Type: news

Spectrum of cardiovascular toxicities with immune checkpoint inhibitors revealed
(Vanderbilt University Medical Center) The study, published online Nov. 12 in The Lancet Oncology, augments previous work by Vanderbilt University Medical Center (VUMC) researchers who first reported in 2016 rare but fatal cardiac side effects from the most widely prescribed class of immunotherapies. The researchers used VigiBase, a global database of drug complications maintained by the World Health Organization, to track adverse cardiovascular reactions in the latest study. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 12, 2018 Category: Cancer & Oncology Source Type: news

AHA: Rivaroxaban May Cut Thromboembolic Risk in HF Patients
(MedPage Today) -- Post hoc analysis of COMMANDER HF trial suggestive of benefit (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 12, 2018 Category: Cardiology Source Type: news

AHA: Endoscopic Vein-Graft Harvesting Redeems Itself in CABG
(MedPage Today) -- Operator expertise takes care of safety concerns (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 11, 2018 Category: Cardiology Source Type: news

Biodegradable-Polymer DES No Better at 10 Years
(MedPage Today) -- Clinical benefit elusive long after polymer should have disappeared (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 11, 2018 Category: Cardiology Source Type: news

AHA: Novel Agent Promising for Lowering Lp(a) Levels
(MedPage Today) -- Treatment with AKCEA-APO(a)-LRx better than placebo at multiple doses (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 11, 2018 Category: Cardiology Source Type: news

AHA: Putting a Price on PCSK9 Inhibitor in ACS
(MedPage Today) -- At $13,000 per year, alirocumab still cost-effective for patients with LDL-C 100 mg/dL (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 11, 2018 Category: Cardiology Source Type: news

AHA: In-hospital Entresto Safe, Beneficial in HFrEF
(MedPage Today) -- PIONEER-HF shows improved biomarkers and possibly outcomes too (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 11, 2018 Category: Cardiology Source Type: news