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Experimental Drug Takes on Injury From Fatty Liver Experimental Drug Takes on Injury From Fatty Liver
An investigative human fibroblast growth factor 19 analog is in development to reduce markers of liver damage in patients with nonalcoholic steatohepatitis.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 20, 2018 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Unlocking the Potential of AI For Fatty Liver Treatments
ReviveMed, a Massachusetts Institute of Technology (MIT) spinout, is using artificial intelligence (AI) to unlock the power of metabolomics to discover new therapies to treat diseases. Metabolomics is the large-scale study of small molecules like glucose or cholesterol produced by cellular activity. ReviveMed’s platform could help pharmaceutical companies redesign existing drugs or develop new drugs to help patients suffering from disease. The Cambridge, MA-based company recently raised funding to help further develop its AI solution, closing an oversubscribed seed round of $1.5 million. Rivas Capital led the round, ...
Source: MDDI - April 19, 2018 Category: Medical Devices Authors: Omar Ford Tags: Software Source Type: news

Poverty Harms Patients With Diabetes, Fatty Liver Poverty Harms Patients With Diabetes, Fatty Liver
When patients with diabetes and nonalcoholic fatty liver disease cannot consistently afford a healthy diet, the risk for advanced hepatic fibrosis is elevated, new research shows.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 17, 2018 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Gains from online lifestyle intervention similar to group program ’s for liver disease patients
In a cohort of patients with non-alcoholic fatty liver disease (NAFLD), an online lifestyle modification-focused intervention was similarly effective to a group-based program in achieving weight loss and liver enzyme normalization, according to data from an Italian study recently presented at The International Liver Congress in Paris. (Source: mobihealthnews)
Source: mobihealthnews - April 16, 2018 Category: Information Technology Source Type: news

' Well Done' Red Meat Linked to Liver Disease, Insulin Resistance'Well Done' Red Meat Linked to Liver Disease, Insulin Resistance
People who eat lots of processed and red meat are at increased risk of developing non-alcoholic fatty liver disease and insulin resistance, especially if they like their steak well done, an Israeli study suggests.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 13, 2018 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Eating red meat boosts the risk of deadly liver disease
Israeli scientists have found the risk of non-alcoholic fatty liver disease is highest for those who enjoy their steak 'well done'. The conclusion was made based on a study of 789 adults. (Source: the Mail online | Health)
Source: the Mail online | Health - April 13, 2018 Category: Consumer Health News Source Type: news

Germany: compensated cirrhosis substantially increases comorbidities and healthcare costs for patients with non-alcoholic fatty liver disease/non-alcoholic steatohepatitis
(European Association for the Study of the Liver) Compensated cirrhosis substantially increases comorbidities and healthcare costs for patients with non-alcoholic fatty liver disease/non-alcoholic steatohepatitis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 13, 2018 Category: International Medicine & Public Health Source Type: news

A Web-based lifestyle intervention supports weight loss in patients with non-alcoholic fatty liver disease
(European Association for the Study of the Liver) A remote lifestyle modification intervention shown to be as effective as a face-to-face group program for weight loss and improved liver health. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 13, 2018 Category: International Medicine & Public Health Source Type: news

Ionis may get up to $300 million in licensing deal with AstraZeneca
(Reuters) - Ionis Pharmaceuticals Inc said on Monday a licensing deal for its fatty liver disease treatment with AstraZeneca Plc could fetch up to $300 million in milestone payments. (Source: Reuters: Health)
Source: Reuters: Health - April 9, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Ionis to get up to $300 million from licensing deal with AstraZeneca
(Reuters) - Ionis Pharmaceuticals said on Monday it signed a licensing deal for its fatty liver disease treatment with AstraZeneca Plc that could land the company up to $300 million in milestone payments and royalties. (Source: Reuters: Health)
Source: Reuters: Health - April 9, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

UCLA scientists discover that cells contain mitochondria specialized to build fats
Mitochondria, known to most people as the “powerhouses of the cell,” have been recognized for decades as the cellular organelle where sugars and fats are oxidized to generate energy. Now, new research by UCLA scientists has found that not all mitochondria fit this definition. Within each cell a group of specialized mitochondria can be f ound attached to fat droplets. Rather than burn fat to create energy, these specialized mitochondria are responsible for providing the energy to build and store fat molecules.“This is really a whole new view of mitochondria and what they can do,” said lead author Dr....
Source: UCLA Newsroom: Health Sciences - April 6, 2018 Category: Universities & Medical Training Source Type: news

PCOS linked to increased liver disease risk
According to a study, published inPLOS Medicine, women with PCOS have double the risk of developing nonalcoholic fatty liver disease.Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - April 6, 2018 Category: Endocrinology Source Type: news

Liver Health Takes a Hit in Kids as Young as 8 Years Old Liver Health Takes a Hit in Kids as Young as 8 Years Old
Children who are obese or overweight in early childhood are at increased risk of developing signs of nonalcoholic fatty liver disease as early as age 8 years, a study found.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 5, 2018 Category: Consumer Health News Tags: Pediatrics News Source Type: news

Liver Health Takes a Hit in Young Overweight Children Liver Health Takes a Hit in Young Overweight Children
Children who are obese or overweight in early childhood are at increased risk of developing signs of nonalcoholic fatty liver disease as early as age 8 years, a study found.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 5, 2018 Category: Consumer Health News Tags: Pediatrics News Source Type: news

Fatty liver disease: Four ways to avoid the SILENT killer
NON-ALCOHOLIC fatty liver disease is one of the UK ’s biggest killers. But with diet and lifestyle changes, the condition is reversible. Here’s how to avoid the disease and try to beat it if you’ve already been diagnosed. (Source: Daily Express - Health)
Source: Daily Express - Health - April 5, 2018 Category: Consumer Health News Source Type: news

Toddlers' Girth Points to Later Risk of Fatty Liver Disease (CME/CE)
(MedPage Today) -- Waist at age 3 linked to elevated ALT levels by age 8 (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - April 4, 2018 Category: Psychiatry Source Type: news

Obesity Can Lead to Liver Damage by Age 8
A new study of 635 children in Massachusetts found that a bigger waist size at age 3 increases the odds that a child will have a marker for liver damage and nonalcoholic fatty liver disease by age 8. (Source: WebMD Health)
Source: WebMD Health - April 4, 2018 Category: Consumer Health News Source Type: news

Obese children are nearly twice as likely to show signs of a life-threatening liver disease
A Columbia University study revealed 35 percent of obese children showed signs of nonalcoholic fatty liver disease, a condition that causes damage similar to that of excessive alcohol consumption. (Source: the Mail online | Health)
Source: the Mail online | Health - April 4, 2018 Category: Consumer Health News Source Type: news

Women with polycystic ovary syndrome at double risk of liver disease
Women with polycystic ovaries having a two-fold increased risk of developing non-alcoholic fatty liver disease, according to UK researchers. (Source: Nursing Times)
Source: Nursing Times - March 29, 2018 Category: Nursing Source Type: news

e-Cigarettes Linked to Fatty Liver Disease in Mice e-Cigarettes Linked to Fatty Liver Disease in Mice
Use of electronic cigarettes combined with a Western diet may raise the risk of fatty liver disease, suggests new research in mice.Reuters Health Information (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - March 26, 2018 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news

Empagliflozin Eyed for Fatty Liver Disease in Type 2 Diabetes Empagliflozin Eyed for Fatty Liver Disease in Type 2 Diabetes
The first trial of the SGLT2 inhibitor empagliflozin in patients with type 2 diabetes and nonalcoholic fatty liver disease indicates the drug might reduce liver fat, but the results of the small study need replication.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 22, 2018 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Fermented tea protects the liver from oxidative stress with antioxidant properties that regulate glucose levels
(Natural News) A lot of diseases, such as fatty liver disease, are caused by oxidative stress. Fortunately, there are natural treatments that help fight it. One of these is a fermented tea called Pu-erh that contains antioxidant properties and glucose-regulating extracts and can protect the liver from impairment. A team of researchers from China examined the oxidative... (Source: NaturalNews.com)
Source: NaturalNews.com - March 22, 2018 Category: Consumer Health News Source Type: news

High consumption of red and processed meat linked to non-alcoholic fatty liver disease and insulin resistance
(Elsevier) World meat consumption has increased during the last decades, and evidence is mounting that high consumption of red and mainly processed meat is unhealthy to humans and is related to chronic diseases such as cancer, type 2 diabetes, and cardiovascular disease. A new study published in the Journal of Hepatology adds non-alcoholic fatty liver disease (NAFLD) to the list. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - March 20, 2018 Category: Biology Source Type: news

Cell Signaling Pathways Point to Top Notch Solution for Fatty Liver Disease
Notch, a type of cell receptor, may be responsible for fat build up in individuals with nonalcoholic fatty liver disease. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news

Gut Microbes Transmit Susceptibility to Nonalcoholic Fatty Liver Disease Progression
Studies have expanded understanding of the role of gut microbes in nonalcoholic fatty liver disease (NAFLD) progression to nonalcoholic steatohepatitis (NASH). (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news

NIH study to test treatment for fatty liver disease in children
(Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news

Gastrointestinal hormone can decrease liver fat levels
According to a clinical study, published inThe Lancet, a variant of hormone FGF19 can reduce the liver fat levels of patients with non-alcoholic fatty liver disease and non-alcoholic steatohepatitis.Science Daily (Source: Society for Endocrinology)
Source: Society for Endocrinology - March 13, 2018 Category: Endocrinology Source Type: news

Post-Transplant Fatty Liver Disease on the Rise (CME/CE)
(MedPage Today) -- Over 25% of liver-transplanted patients had new-onset NAFLD (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - March 10, 2018 Category: Gastroenterology Source Type: news

Gastrointestinal hormone measurably improved symptoms of non-alcoholic fatty liver disease
(University of California - San Diego) Through a randomized, double-blind, placebo-controlled phase II clinical trial, researchers at University of California San Diego School of Medicine report that small doses of NGM282, a non-tumorigenic variant of an endocrine gastrointestinal hormone, can significantly and rapidly decrease liver fat content in patients with non-alcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). The findings represent an important proof-of-concept for the compound as there are currently no Food and Drug Administration-approved treatments for NAFLD and NASH. (Source: EurekAle...
Source: EurekAlert! - Medicine and Health - March 8, 2018 Category: International Medicine & Public Health Source Type: news

Combating childhood obesity by preventing 'fatty liver' in fetus
(The Physiological Society) New research published in The Journal of Physiology indicates that an obese pregnant mother and exposure to a high fat, high sugar diet during pregnancy produces a 'fatty liver' in the fetus, potentially predisposing children to obesity, metabolic and cardiovascular disorders later in life. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 7, 2018 Category: Cancer & Oncology Source Type: news

Zebra Medical wins CE Mark for brain-bleed detection algorithm
Israeli machine-learning radiology firm Zebra Medical Vision said today it won CE Mark approval in the European Union for an algorithm for detecting intracranial hemorrhages as part of its deep learning imaging analytics platform. Zebra Medical said that its algorithm is designed to identify brain bleeds to provide extra support for physicians in acute care settings, and that it plans to use the algorithm for point-of-care detection to identify bleeds accurately and with reduced delay. “This new algorithm is an important addition to Zebra’s Analytics Engine. The ability to alert radiologists and surgeons t...
Source: Mass Device - March 6, 2018 Category: Medical Devices Authors: Fink Densford Tags: Neurological Regulatory/Compliance Software / IT Zebra Medical Vision Source Type: news

Pearls From: Bryan Rudolph, MD
(MedPage Today) -- Fatty liver disease a growing problem in children (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - March 5, 2018 Category: Pediatrics Source Type: news

Diagnostic Performance of Noninvasive Fibrosis Tests in NAFLD Diagnostic Performance of Noninvasive Fibrosis Tests in NAFLD
What factors may impact the diagnostic performance of noninvasive fibrosis tests in patients with nonalcoholic fatty liver disease? Does accuracy differ across various NAFLD subgroups?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 1, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Texas A & M-led collaborative study takes aim at non-alcoholic fatty liver disease
(Texas A&M AgriLife Communications) Texas A&M University System researchers in collaboration with the Department of Veterans Affairs and Baylor Scott& White Research Institute have completed a study identifying one of the mechanisms leading to the development of non-alcoholic fatty liver disease, or NAFLD, providing new possibilities for prevention and treatment of the disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2018 Category: International Medicine & Public Health Source Type: news

Medical News Today: Cutting back on carbs could help treat fatty liver disease
A new study reveals how reducing the intake of carbohydrates could help to reduce the buildup of liver fat in people who are obese. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 19, 2018 Category: Consumer Health News Tags: Nutrition / Diet Source Type: news

Digital liver scanning technology could halve the number of liver biopsies needed in the NHS
(University of Birmingham) A study has revealed that a new scanning technology could almost halve the number of liver biopsies carried out on people with fatty liver disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 13, 2018 Category: International Medicine & Public Health Source Type: news

Medical News Today: Fish oil may not be as healthful as you think, study finds
A new study finds that lifelong intake of fish or sunflower oil may damage the liver in a way that increases the risk of non-alcoholic fatty liver disease. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 4, 2018 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

Medical News Today: Kiwi compound may prevent non-alcoholic fatty liver disease
Research suggests that a compound found in kiwi and celery may prevent fatty liver in offspring born to mothers who ate a high-fat diet in pregnancy. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 28, 2018 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

BU researcher awarded NIH grant to continue research on non-alcoholic fatty liver disease
(Boston University School of Medicine) Michelle T. Long, MD, assistant professor of medicine at Boston University School of Medicine (BUSM) and a gastroenterologist at Boston Medical Center (BMC), recently was a awarded nearly $1 million dollars from the National Institutes of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH). The five-year grant will continue to fund her research on non-alcoholic fatty liver disease (NAFLD). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 26, 2018 Category: International Medicine & Public Health Source Type: news

Hospital shakes are filled with sugar, experts warn
Experts warn meal replacement shakes like Boost and Ensure contain refined sugars linked to health conditions such as type 2 diabetes, heart disease and fatty liver disease. (Source: the Mail online | Health)
Source: the Mail online | Health - January 25, 2018 Category: Consumer Health News Source Type: news

Liver disease solutions proven to be safe and effective
(Natural News) Non-alcoholic fatty liver disease (NAFLD), the presence of excess fat in the liver, is approaching epidemic proportions – with experts estimating the prevalence at 20 to 30 percent worldwide. And, since NAFLD is strongly linked to being overweight, the alarming rise of liver disease is expected to continue. But, according to natural health... (Source: NaturalNews.com)
Source: NaturalNews.com - January 24, 2018 Category: Consumer Health News Source Type: news

Powerful food-derived antioxidant can halt, prevent fatty liver disease in mice
(University of Colorado Anschutz Medical Campus) As obesity continues to rise in the US, non-alcoholic fatty liver disease (NAFLD) has become a major public health issue, increasingly leading to cancer and liver transplants. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 22, 2018 Category: International Medicine & Public Health Source Type: news

Novartis becomes latest big-name collaborator for Chapel Hill company
On the heels of collaborations with Bristol-Myers Squibb (NYSE: BMY) and Allergan (NYSE: AGN), Chapel Hill-based clinical data company Target PharmaSolutions ’ latest collaboration is with Novartis (NYSE: NVS). Novartis will collaborate with Target on its NASH study, focused on patients with nonalcoholic fatty liver disease (NAFLD) or nonalcoholic steatohepatitis (NASH). The study will ultimately enroll 15,000 patients.  While financial terms of the new collaboration are not being disclosed,… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - January 10, 2018 Category: American Health Authors: Jennifer Henderson Source Type: news

Noninvasive Tests for NAFLD Are Unreliable in South Asians Noninvasive Tests for NAFLD Are Unreliable in South Asians
Blood-test-based non-invasive tests for non-alcoholic fatty liver disease (NAFLD) are unreliable alternatives to liver biopsy in South Asians, new research suggests.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 28, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Non-alcoholic fatty disease liver disease associated with higher cardiovascular risk
Results presented during the American Heart Association Scientific Sessions report that non-alcoholic fatty liver disease may have a role in cardiovascular risk.Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - December 22, 2017 Category: Endocrinology Source Type: news

What is DIOS?
Discussion Cystic fibrosis (CF) is an autosomal recessive disorder caused by mutations in the cystic fibrosis transmembrane receptor (CFTR). It is found in the epithelium of the bronchi, intestine, pancreatic duct and biliary tree. It regulates chloride, bicarbonate and water secretion. The heterozygous state helps prevent against secretory diarrhea, but the homozygous state causes thickened secretions in the hollow tubes of the lungs and digestive tract. There are multiple mutations (> 2000) which have been currently classified into classes depending on their protein production and activity. CF patients generally are l...
Source: PediatricEducation.org - December 18, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Ongoing Trials Put Focus Back on Fatty Liver Disease Ongoing Trials Put Focus Back on Fatty Liver Disease
Researchers at this year's Liver Meeting offered promising insights into nonalcoholic steatohepatitis and fatty liver disease. Dr William Balistreri surveys their results.Medscape Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 11, 2017 Category: Consumer Health News Tags: Gastroenterology Commentary Source Type: news

Galectin slumps after NASH drug misses main goal of mid-stage trial
(Reuters) - Galectin Therapeutics Inc said its drug for the complex progressive fatty liver disease NASH led to some clinically meaningful results in patients with cirrhosis, but failed to achieve the main goal of a mid-stage trial, sending its shares plunging 48 percent on Tuesday. (Source: Reuters: Health)
Source: Reuters: Health - December 5, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Galectin says NASH drug misses main goal of midstage trial
(Reuters) - Galectin Therapeutics Inc said on Tuesday its experimental drug for the complex progressive fatty liver disease NASH led to some clinically meaningful results in patients with cirrhosis, but failed to achieve the main goal of a midstage trial. (Source: Reuters: Health)
Source: Reuters: Health - December 5, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

FDA Approves MRI Software for Fatty Liver Disease Screening FDA Approves MRI Software for Fatty Liver Disease Screening
The diagnosis of nonalcoholic fatty liver disease, which can rapidly progress to cirrhosis or liver cancer, could become easier with new multiparametric MRI software.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 4, 2017 Category: Consumer Health News Tags: Radiology News Source Type: news