Fatty Liver Disease-A Multifaceted Disease With Multiple Names? Fatty Liver Disease-A Multifaceted Disease With Multiple Names?
In this commentary, the authors suggest that a more precise terminology for NAFLD is needed, with a more granular view on subcategories of NASH to guide preventive and therapeutic measures.Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 7, 2021 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Triclosan worsens fatty liver disease in mice
The antibacterial compound, found in consumer products and some drinking water, worsened liver health in diabetic mice fed a high-fat diet. (read more) (Source: Environmental Factor - NIEHS Newsletter)
Source: Environmental Factor - NIEHS Newsletter - January 6, 2021 Category: Environmental Health Source Type: news

Zydus Cadila receives DCGI nod for NAFLD drug Saroglitazar Mg in India
Non-Alcoholic Fatty Liver Disease (NAFLD) is a progressive disease of the liver, which starts with fat accumulation in the liver in patients who do not consume alcohol or take it in insignificant amounts, but have risk factors such as overweight or obesity, diabetes mellitus (high blood sugar), hypertension (high blood pressure) or dyslipidemia (abnormal blood lipids). (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - December 30, 2020 Category: Pharmaceuticals Source Type: news

In liver, a stressed cell can be bad news for its neighbors
(Harvard T.H. Chan School of Public Health) When a stressed liver cell starts communicating with its neighbors, it can send stress signals to neighboring cells, causing significant problems that can lead to fatty liver disease and metabolic disease. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - December 18, 2020 Category: Biology Source Type: news

Mayo Clinic Q & amp;A podcast: Two ends of the nutrition spectrum in children
Pediatric growth charts track growth in infants, children and adolescents. While children can go through brief periods where they gain or lose a little weight, if children don't gain weight or grow well, they may be diagnosed with failure to thrive. On the other end of the nutrition spectrum are children with non-alcoholic fatty liver [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - December 4, 2020 Category: Databases & Libraries Source Type: news

Sensor can detect scarred or fatty liver tissue
(Massachusetts Institute of Technology) MIT engineers have now developed a diagnostic tool, based on nuclear magnetic resonance (NMR), that could be used to detect both fatty liver disease and liver fibrosis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 2, 2020 Category: International Medicine & Public Health Source Type: news

Study: gut hormones' regulation of fat production abnormal in obesity, fatty liver disease
(University of Illinois at Urbana-Champaign, News Bureau) Gut hormones play an important role in regulating fat production in the body. One key hormone, released a few hours after eating, turns off fat production by regulating gene expression in the liver, but this regulation is abnormal in obesity, researchers at the University of Illinois Urbana-Champaign found in a new study. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 24, 2020 Category: International Medicine & Public Health Source Type: news

Antimicrobial soap additive worsens fatty liver disease in mice
(University of California - San Diego) Triclosan, an antimicrobial found in many soaps and other household items, worsens fatty liver disease in mice fed a high-fat diet. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 23, 2020 Category: International Medicine & Public Health Source Type: news

NAFLD Prevalence Rising Among Children but Many Undiagnosed NAFLD Prevalence Rising Among Children but Many Undiagnosed
The incidence of nonalcoholic fatty liver disease (NAFLD) is rising among children, but not all youth with obesity are getting recommended screening, a study in California suggests.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 20, 2020 Category: Consumer Health News Tags: Pediatrics News Source Type: news

2009 to 2018 Saw Increase in Incidence of NAFLD in Children
THURSDAY, Nov. 19, 2020 -- From 2009 to 2018, there was an increase in the incidence of nonalcoholic fatty liver disease (NAFLD) among children, although many still remain undiagnosed, according to a study published online Nov. 19 in... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 19, 2020 Category: Pharmaceuticals Source Type: news

Lipid Profiles Distinguish Obese and Nonobese NAFLD Patients Lipid Profiles Distinguish Obese and Nonobese NAFLD Patients
Both obese and nonobese individuals can develop nonalcoholic fatty liver disease, and lipid profiles were effective predictors in both groups, based on data from a cross-sectional study.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 13, 2020 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Mayo Clinic Q & amp;A podcast: Cardiometabolic diseases increase COVID-19 risk
An estimated 47 million Americans are living with cardiometabolic diseases, according to the American College of Cardiology. Cardiometabolic diseases are interrelated conditions that include cardiovascular diseases, such as heart disease, stroke, and hypertension, as well as metabolic diseases, such as Type 2 diabetes, obesity and nonalcoholic fatty liver disease. Patients with cardiometabolic diseases have a [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - November 13, 2020 Category: Databases & Libraries Source Type: news

Dietary supplement may help in the treatment of fatty liver
(University of Jyv ä skyl ä - Jyv ä skyl ä n yliopisto) A recent study by researchers at the University of Jyv ä skyl ä was successful in partially preventing fatty liver disease in rats. Rats with fatty liver disease were fed with a dietary supplement that is known to increase the growth of good bacteria in the gut. Simultaneous with the increased abundance of the bacteria, the liver fat content decreased significantly. In addition, preliminary results from a human study seem promising. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 4, 2020 Category: International Medicine & Public Health Source Type: news

How Serious Is a Fatty Liver
? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - October 29, 2020 Category: General Medicine Source Type: news

Eating less suppresses liver cancer due to fatty liver
(Shinshu University) Liver cancer from too much fat accumulation in the liver has been increasing in many countries including Japan. In order to change this unfortunate state of affairs, it is important to improve the prognosis of non-alcoholic fatty liver disease. Fatty liver is often improved through eating less, getting more exercise, and reducing body weight. The research group posed the question, " Can eating less also suppress liver cancer caused by fatty liver? " (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 29, 2020 Category: Cancer & Oncology Source Type: news

Start-up awarded grant to develop contrast agent for early detection of liver disease
(Georgia State University) Inlighta Biosciences, LLC, a start-up company led by Jenny Yang, Regents' Professor of Chemistry at Georgia State University, has been awarded a National Institute of Health grant to accelerate development of a magnetic resonance imaging contrast agent to detect liver fibrosis, formation of scar tissue in the liver caused by alcoholic and non-alcoholic fatty liver disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 15, 2020 Category: International Medicine & Public Health Source Type: news

Predictors of Mortality and Disease Progression in NAFLD Predictors of Mortality and Disease Progression in NAFLD
This study aimed to elucidate the factors associated with mortality and disease progression in non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in a real-world cohort.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 14, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

NAFLD Closely Tied to Diabetes Risk NAFLD Closely Tied to Diabetes Risk
Patients with non-alcoholic fatty-liver disease (NAFLD) have a higher risk of diabetes, and the more severe the disease the greater the risk, according to new research.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - October 8, 2020 Category: Pathology Tags: Gastroenterology News Source Type: news

Newer Antidiabetic Drugs Linked to Improved Liver Enzymes, Steatosis Newer Antidiabetic Drugs Linked to Improved Liver Enzymes, Steatosis
Early evidence suggests that newer diabetes drugs such as pioglitazone may improve liver enzymes and hepatic steatosis and could possibly be useful in treating non-alcoholic fatty liver disease (NAFLD), researchers say.Reuters Health Information (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - October 6, 2020 Category: Endocrinology Tags: Gastroenterology News Source Type: news

Comparison of MAFLD and NAFLD Diagnostic Criteria in Real World Comparison of MAFLD and NAFLD Diagnostic Criteria in Real World
How does the criteria for the newly-coined concept"metabolic associated fatty liver disease" differ from those for non-alcoholic fatty liver disease, and what are the real-world implications?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 28, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

AI plus CT improves liver steatosis assessment
Artificial intelligence (AI) used with contrast-enhanced abdominal CT makes...Read more on AuntMinnie.comRelated Reading: Can AI screen for nonalcoholic fatty liver disease? Ultrasound useful for evaluating liver steatosis MRI offers view of liver fat loss in obese patients Steatosis complicates MR elastography for liver fibrosis AIUM: Can deep learning classify liver fibrosis on US? (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - September 22, 2020 Category: Radiology Source Type: news

MAFLD Is Associated With Severity of Covid-19 MAFLD Is Associated With Severity of Covid-19
Does the co-occurence of metabolic-associated fatty liver disease in patients with COVID-19 increase the risk of severe disease?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 21, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

CNIC researchers discover a mechanism allowing immune cells to regulate obesity
(Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)) A CNIC's team have discovered a mechanism explaining how macrophages regulate obesity. The results published in Nature Metabolism could be useful to design new treatments for the obese and overweight, and for some associated pathologies, including fatty liver disease and type 2 diabetes. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - September 17, 2020 Category: International Medicine & Public Health Source Type: news

How high fructose intake may trigger fatty liver disease
A study suggested that consuming high amounts of fructose may promote non-alcoholic fatty liver disease by damaging the intestinal barrier. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - September 14, 2020 Category: Consumer Health News Source Type: news

Researchers find molecular link between liver disease, insulin resistance
Yale researchers have zeroed in on a molecular link between nonalcoholic fatty liver disease and liver insulin resistance in type 2 diabetes. (Source: Yale Science and Health News)
Source: Yale Science and Health News - September 2, 2020 Category: Universities & Medical Training Source Type: news

Menopause may increase risk for non-alcoholic fatty liver disease
Postmenopausal women may be more likely to develop non-alcoholic fatty liver disease due to a reduction in sex hormones, suggests a study published in Endocrinology.News Medical (Source: Society for Endocrinology)
Source: Society for Endocrinology - August 26, 2020 Category: Endocrinology Source Type: news

New insights into mechanism of therapy to reduce liver fat and prevent fibrosis
(Massachusetts General Hospital) A team led by researchers at Massachusetts General Hospital (MGH) has taken an important step forward in the goal of developing a potential treatment for non-alcoholic fatty liver disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 26, 2020 Category: International Medicine & Public Health Source Type: news

Excessive fructose consumption may cause a leaky gut, leading to fatty liver disease
(University of California - San Diego) Researchers at University of California San Diego School of Medicine report that fructose only adversely affects the liver after it reaches the intestines, where the sugar disrupts the epithelial barrier protecting internal organs from bacterial toxins in the gut (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 24, 2020 Category: International Medicine & Public Health Source Type: news

Is turning back the clock in aging fat cells a remedy for lifestyle diseases?
(Osaka University) Researchers from Osaka University found that lifestyle diseases such as diabetes, high cholesterol, and fatty liver are caused by age-related changes in fat cells. Loss of a protein called Rubicon in aged adipocytes allows intracellular degradation processes to kick into overdrive, disrupting normal cellular function and causing the onset of lifestyle diseases. By inhibiting this degradation and restoring a more youthful cellular environment, we may be able to prevent the onset of lifestyle diseases. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - August 18, 2020 Category: International Medicine & Public Health Source Type: news

TGen review suggests postmenopausal women at risk for nonalcoholic fatty liver disease
(The Translational Genomics Research Institute) NAFLD is the most common cause of liver damage, and can lead to liver cirrhosis and death. It affects nearly 1 in 4 people across the globe. It often is associated with obesity, abnormally high amounts of lipids in the blood, and type 2 diabetes. In the US, the number of NAFLD cases is expected to grow to more than 100 million within the next decade, annually costing an estimated at $292 billion. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 14, 2020 Category: International Medicine & Public Health Source Type: news

NAFLD May Predict Arrhythmia Recurrence Post-AF Ablation NAFLD May Predict Arrhythmia Recurrence Post-AF Ablation
The presence of nonalcoholic fatty liver disease adds a further modifiable target for preablation medical optimization, researchers say.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - August 14, 2020 Category: Cardiology Tags: Cardiology News Source Type: news

Fatty liver disease despite a normal weight
(University of Tsukuba) Researchers from the University of Tsukuba found significant differences in the clinical presentation of non-obese patients with non-alcoholic fatty liver disease (NAFLD) based on their sex and body mass index. They found that non-obese NAFLD patients had lower muscle mass and strength (pre-sarcopenia) compared to obese NAFLD patients. Further, fat accumulation in muscles was more common among women. These findings help us understand the clinical presentation of NAFLD. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 3, 2020 Category: International Medicine & Public Health Source Type: news

Insight on novel genetic approaches to metabolic liver diseases
(Wayne State University - Office of the Vice President for Research) Faculty from Wayne State University's Eugene Applebaum College of Pharmacy and Health Sciences are leading a team of researchers to understand the causal relationships between diabetes, obesity and nonalcoholic fatty liver disease in hopes of developing a treatment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 31, 2020 Category: International Medicine & Public Health Source Type: news

Limp handshake? You may be at risk of a potentially fatal liver disease
While social distancing means it's currently barred, new research has revealed that a limp handshake or a weak grip could be an early warning sign of non-alcoholic fatty liver disease. (Source: the Mail online | Health)
Source: the Mail online | Health - July 13, 2020 Category: Consumer Health News Source Type: news

Doctors call fatty liver disease a growing public health concern in Canada
Doctors are warning that soaring rates of a common, but often undetected, liver disease could impose an enormous burden on Canadian health care over the next decade if there isn't more public awareness. (Source: CBC | Health)
Source: CBC | Health - July 13, 2020 Category: Consumer Health News Tags: News/Health Source Type: news

In race to defeat fatty liver disease, Peninsula biotech lines up next clinical trial
In the race to find a drug for the fatty liver disease NASH, George Kemble isn ’t dissuaded by Sagimet Biosciences’ size; it’s the data that count. And after pivots by the San Mateo company that Kemble heads, it has promising early data back from a mid-stage study of its drug targeting nonalcoholic steatohepatitis, or NASH, and plans to take the drug into another mid-st age study early next year. The Phase II study results come as larger companies have released promising data of their own.… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - July 10, 2020 Category: Pharmaceuticals Authors: Ron Leuty Source Type: news

In race to defeat fatty liver disease, Peninsula biotech lines up next clinical trial
In the race to find a drug for the fatty liver disease NASH, George Kemble isn ’t dissuaded by Sagimet Biosciences’ size; it’s the data that count. And after pivots by the San Mateo company that Kemble heads, it has promising early data back from a mid-stage study of its drug targeting nonalcoholic steatohepatitis, or NASH, and plans to take the drug into another mid-st age study early next year. The Phase II study results come as larger companies have released promising data of their own.… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - July 10, 2020 Category: Biotechnology Authors: Ron Leuty Source Type: news

Researchers find promising therapy to fight epidemic of liver disease
(University of Colorado Anschutz Medical Campus) In an effort to combat a growing worldwide epidemic of Nonalcoholic Fatty Liver Disease (NAFLD), scientists have discovered a new target and a new therapy that has shown promising results in preclinical mouse models, according to researchers at the University of Colorado Anschutz Medical Campus. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 8, 2020 Category: Biology Source Type: news

U of SC: How non-alcoholic fatty liver disease causes Alzheimer's-like neuroinflammation
(University of South Carolina) Research from UofSC associate professor Saurabh Chatterjee's laboratory in Environmental Health Sciences at the Arnold School of Public Health has revealed the cause behind the previously established link between non-alcoholic fatty liver disease and neurological problems. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 6, 2020 Category: International Medicine & Public Health Source Type: news

Tamoxifen-related NAFLD: Prevalence, Incidence, Risk Factors Tamoxifen-related NAFLD: Prevalence, Incidence, Risk Factors
How common is the development of fatty liver after tamoxifen treatment in breast cancer patients, and what are the associated risk factors?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 3, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

The gut shields the liver from fructose-induced damage
(University of Pennsylvania School of Medicine) After one consumes food or a beverage containing fructose, the gastrointestinal system, or gut, helps to shield the liver from damage by breaking down the sugar before it reaches the liver, according to a new multi-center study. However, the consumption of too much fructose--particularly in a short period of time--can overwhelm the gut, causing fructose to " spill over " into the liver, where it wreaks havoc and causes fatty liver, researchers discovered. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 29, 2020 Category: International Medicine & Public Health Source Type: news

Curb the symptoms of non-alcoholic fatty liver disease by adopting a Mediterranean diet
(Natural News) Multiple studies have found that eating more fish and plant-based foods like fruits, vegetables and whole grains — typical components of the Mediterranean diet — contribute to good health even in old age. According to Harvard Medical School researchers, people who stick to a Mediterranean diet have a 46 percent higher chance of healthy... (Source: NaturalNews.com)
Source: NaturalNews.com - June 26, 2020 Category: Consumer Health News Source Type: news

Fatty liver sufferers more likely to be hospitalised with Covid-19, study found
FATTY liver disease is a major risk factor for potentially deadly complications of coronavirus, a groundbreaking new study shows. (Source: Daily Express - Health)
Source: Daily Express - Health - June 21, 2020 Category: Consumer Health News Source Type: news

Novel antisense drug shows promise in slowing fatty liver disease
(University of California - San Diego) A first-in-class clinical trial suggests a novel treatment measurably slowed progression of non-alcoholic fatty liver disease to its more progressive and deadly form. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 16, 2020 Category: International Medicine & Public Health Source Type: news

Risk for Maternal, Neonatal Complications Increased With NAFLD
TUESDAY, June 9, 2020 -- Women with non-alcoholic fatty liver disease (NAFLD) have increased risks for maternal and neonatal complications, according to a study published online June 9 in the Journal of Hepatology. Monika Sarkar, M.D., from the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 9, 2020 Category: Pharmaceuticals Source Type: news

Fecal transplants show promise as treatment for non-alcoholic fatty liver disease
(Lawson Health Research Institute) A new study from Lawson Health Research Institute and Western University suggests that fecal transplants could be used as a treatment for non-alcoholic fatty liver disease (NAFLD). The randomized controlled trial published in The American Journal of Gastroenterology found that fecal transplants in patients with NAFLD result in a reduction in how easily pathogens and other unwanted molecules pass through the human gut and into circulation, known as intestinal permeability. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 9, 2020 Category: International Medicine & Public Health Source Type: news

Mediterranean diet found to ameliorate symptoms of nonalcoholic fatty liver disease
In this study, Greek researchers investigated the effects of the Mediterranean diet (MedDiet) on the clinical, biochemical and inflammatory profile of patients with simple liver steatosis. Their results were published in the Journal of Medicinal Food. Diet is a modifiable key factor and target for the prevention or management of non-alcoholic fatty liver disease (NAFLD).... (Source: NaturalNews.com)
Source: NaturalNews.com - June 2, 2020 Category: Consumer Health News Source Type: news

An imbalance of electrons in the liver may be a common risk factor for disease
(Massachusetts General Hospital) Researchers at Massachusetts General Hospital have uncovered an unexpected connection between an imbalance of electrons in liver cells and many metabolic problems that increase the risk for conditions such as cardiovascular disease and fatty liver disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 28, 2020 Category: International Medicine & Public Health Source Type: news

Modified Parkinson's drug shows potential in treating nonalcoholic fatty liver disease
(GIST(Gwangju Institute of Science and Technology)) Nonalcoholic fatty liver disease (NAFLD) severely impairs the quality of life in patients and often leads to various liver complications. Recently, scientists at Gwangju Institute of Science and Technology designed a novel compound that can potentially treat NAFLD by targeting peripheral serotonin, which regulates lipid metabolism in the liver. They achieved this by structurally modifying an existing neurological drug such that it targets peripheral serotonin by minimizing brain penetration. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - May 28, 2020 Category: Biology Source Type: news

More Severe COVID-19 in Patients With Liver Fibrosis More Severe COVID-19 in Patients With Liver Fibrosis
Patients with non-alcoholic fatty liver disease (NAFLD) and increased liver-fibrosis scores experience more severe illness from COVID-19, according to a study of Chinese patients.Reuters Health Information (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - May 26, 2020 Category: Intensive Care Tags: Gastroenterology News Source Type: news