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Novartis becomes latest big-name collaborator for Chapel Hill company
On the heels of collaborations with Bristol-Myers Squibb (NYSE: BMY) and Allergan (NYSE: AGN), Chapel Hill-based clinical data company Target PharmaSolutions ’ latest collaboration is with Novartis (NYSE: NVS). Novartis will collaborate with Target on its NASH study, focused on patients with nonalcoholic fatty liver disease (NAFLD) or nonalcoholic steatohepatitis (NASH). The study will ultimately enroll 15,000 patients.  While financial terms of the new collaboration are not being disclosed,… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - January 10, 2018 Category: American Health Authors: Jennifer Henderson Source Type: news

Noninvasive Tests for NAFLD Are Unreliable in South Asians Noninvasive Tests for NAFLD Are Unreliable in South Asians
Blood-test-based non-invasive tests for non-alcoholic fatty liver disease (NAFLD) are unreliable alternatives to liver biopsy in South Asians, new research suggests.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 28, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Non-alcoholic fatty disease liver disease associated with higher cardiovascular risk
Results presented during the American Heart Association Scientific Sessions report that non-alcoholic fatty liver disease may have a role in cardiovascular risk.Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - December 22, 2017 Category: Endocrinology Source Type: news

What is DIOS?
Discussion Cystic fibrosis (CF) is an autosomal recessive disorder caused by mutations in the cystic fibrosis transmembrane receptor (CFTR). It is found in the epithelium of the bronchi, intestine, pancreatic duct and biliary tree. It regulates chloride, bicarbonate and water secretion. The heterozygous state helps prevent against secretory diarrhea, but the homozygous state causes thickened secretions in the hollow tubes of the lungs and digestive tract. There are multiple mutations (> 2000) which have been currently classified into classes depending on their protein production and activity. CF patients generally are l...
Source: PediatricEducation.org - December 18, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Ongoing Trials Put Focus Back on Fatty Liver Disease Ongoing Trials Put Focus Back on Fatty Liver Disease
Researchers at this year's Liver Meeting offered promising insights into nonalcoholic steatohepatitis and fatty liver disease. Dr William Balistreri surveys their results.Medscape Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 11, 2017 Category: Consumer Health News Tags: Gastroenterology Commentary Source Type: news

Galectin slumps after NASH drug misses main goal of mid-stage trial
(Reuters) - Galectin Therapeutics Inc said its drug for the complex progressive fatty liver disease NASH led to some clinically meaningful results in patients with cirrhosis, but failed to achieve the main goal of a mid-stage trial, sending its shares plunging 48 percent on Tuesday. (Source: Reuters: Health)
Source: Reuters: Health - December 5, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Galectin says NASH drug misses main goal of midstage trial
(Reuters) - Galectin Therapeutics Inc said on Tuesday its experimental drug for the complex progressive fatty liver disease NASH led to some clinically meaningful results in patients with cirrhosis, but failed to achieve the main goal of a midstage trial. (Source: Reuters: Health)
Source: Reuters: Health - December 5, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

FDA Approves MRI Software for Fatty Liver Disease Screening FDA Approves MRI Software for Fatty Liver Disease Screening
The diagnosis of nonalcoholic fatty liver disease, which can rapidly progress to cirrhosis or liver cancer, could become easier with new multiparametric MRI software.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 4, 2017 Category: Consumer Health News Tags: Radiology News Source Type: news

Fatty Liver Linked to a Shrinking Brain Fatty Liver Linked to a Shrinking Brain
Fatty liver disease that is not related to excess drinking is associated with greater brain shrinkage than normally happens with age, researchers say.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 27, 2017 Category: Consumer Health News Tags: Medscape Today News Source Type: news

New Treatments in Non-alcoholic Fatty Liver Disease New Treatments in Non-alcoholic Fatty Liver Disease
An improved understanding of the mechanisms behind NAFLD has led to new approaches to pharmacotherapy. This review presents an overview of current and investigational therapeutics.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 27, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Fatty liver linked to a shrinking brain
(Reuters Health) - Fatty liver disease that is not related to excess drinking is associated with greater brain shrinkage than normally happens with age, researchers say. (Source: Reuters: Health)
Source: Reuters: Health - November 23, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Ground-breaking € 34 million project to develop better test for liver disease
(European Association for the Study of the Liver) A pioneering European research project aims to lead to new diagnostic tests to assess patients with non-alcoholic fatty liver disease (NAFLD) and identify those most at risk for developing severe inflammation and liver scarring. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 21, 2017 Category: International Medicine & Public Health Source Type: news

Medical News Today: What to eat for a fatty liver
Making good dietary choices and exercising regularly can effectively manage fatty liver disease. Learn more about foods to eat and foods to avoid. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 20, 2017 Category: Consumer Health News Tags: Nutrition / Diet Source Type: news

Ground-breaking € 34 million project to develop better test for liver disease
(Newcastle University) A pioneering European research project aims to lead to new diagnostic tests to assess patients with non-alcoholic fatty liver disease (NAFLD) and identify those most at risk for developing severe inflammation and liver scarring. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 20, 2017 Category: International Medicine & Public Health Source Type: news

Fatty Liver Disease
Fatty Liver (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - November 17, 2017 Category: General Medicine Source Type: news

Nonalcoholic fatty liver disease increases risk of liver, colorectal, and breast cancers
(Elsevier) Nonalcoholic fatty liver disease (NAFLD) is one of the more common chronic liver diseases worldwide. It is associated with metabolic syndrome (i.e. insulin resistance and diabetes) and predisposes to cardiovascular disease. In a new study published in the Journal of Hepatology, researchers identified links not only between NAFLD and hepatocellular carcinoma (HCC), which have been well established, but also to cancers outside the liver, including colorectal and breast cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 13, 2017 Category: Cancer & Oncology Source Type: news

Living with NASH: An Unexpected Diagnosis
As our waistlines thicken and our activity levels decrease, another chronic illness threatens to disturb our comfortable lifestyles. And, because it ’s relatively unknown, diagnosis comes as a shock to patients, who usually associate liver disease with heavy consumption of alcohol.Non-alcoholic steatohepatitis (NASH) is an advanced form of non-alcoholic fatty liver disease (NAFLD), where fat accumulates in the liver. It is most commonly associated with obesity, insulin resistance, metabolic syndrome and/or genetic polymorphisms, and is aggravated by inflammation and fibrosis.  First identified in the 1980s, its ...
Source: EyeForPharma - November 3, 2017 Category: Pharmaceuticals Authors: Mariel Metcalfe Source Type: news

Psoriasis patients at higher risk for liver disease
Study compares inflammatory illnesses Related items fromOnMedica GPs to get help to boost early detection of liver disease Benefits of exercise training in women with fatty liver disease Psoriasis photo library Rheumatoid arthritis Drug for rheumatoid arthritis appears to have effect on severe eczema (Source: OnMedica Latest News)
Source: OnMedica Latest News - November 3, 2017 Category: UK Health Source Type: news

Probiotics and Omega-3s for Fatty Liver Cut Steatosis Risk Probiotics and Omega-3s for Fatty Liver Cut Steatosis Risk
Preventing and treating nonalcoholic fatty liver disease is a growing challenge, but Ukrainian investigators have successfully translated their promising animal findings to the clinical setting.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 2, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Fatty Liver Common After Direct-Acting Antivirals for Hep C Fatty Liver Common After Direct-Acting Antivirals for Hep C
After hepatitis C is cured, patients should be monitored for steatosis and progression to fibrosis, new research indicates.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 30, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Fatty liver disease on the rise in children—from too many sweet treats
(Natural News) A sweetener used in ice cream and soda may cause potentially fatal liver disease, a new study suggests. Researchers have found that high fructose consumption is triggering an early form of fatty liver disease in children, a condition that is normally associated with alcohol consumption, which can lead to cancer, stroke, and heart... (Source: NaturalNews.com)
Source: NaturalNews.com - October 27, 2017 Category: Consumer Health News Source Type: news

Experts Raise Red Flag over Fatty Liver Disease
(MedPage Today) -- Paints gloomy picture for population health, economy (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - October 25, 2017 Category: Endocrinology Source Type: news

Primary Care Screening for Fatty Liver Disease Debated Primary Care Screening for Fatty Liver Disease Debated
The use of transient elastography to screen for liver fibrosis in the primary care setting can be effective, preliminary data suggest, but not everyone is convinced.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 23, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Even "healthy people," if they eat sugar, are at risk for heart disease, new study finds
(Natural News) New research reveals that even healthy people who consume a high-sugar diet are prone to heart disease. To reach this conclusion, researchers from the University of Surrey in the United Kingdom examined two groups of men, 11 of whom had a fatty liver or also known as non-alcoholic fatty liver disease (NAFLD), while... (Source: NaturalNews.com)
Source: NaturalNews.com - October 23, 2017 Category: Consumer Health News Source Type: news

NAFLD Increases Risk for Cardiovascular Events in Women NAFLD Increases Risk for Cardiovascular Events in Women
In the general population, women tend to be at lower risk for cardiovascular events than men, but the presence of nonalcoholic fatty liver disease appears to change that, a new study finds.Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 23, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Weight Loss in Italy?
One of the women I work with wanted to know about the new diet drug called Belviq. The FDA is always approving a new “miracle” weight-loss pill, only to recall it a few years later. To date, at least 34 diet drugs have been taken off the market. Diet pills cause all kinds of problems — heart attack, stroke and psychiatric disorders. And Belviq isn’t any different. Some of its side effects include suicidal thoughts, a racing heartbeat, hallucinations and more… The European Union banned Belviq. The reason? It causes cancer in animals.  And here’s the real irony… Clinical tri...
Source: Al Sears, MD Natural Remedies - October 19, 2017 Category: Complementary Medicine Authors: Cathy Card Tags: Anti-Aging Source Type: news

Prostate problem? Take 2 nuts
By age 60, you have a 50/50 chance of having a clinically enlarged prostate. And it only gets worse every year. When your prostate isn’t functioning properly, it’s hard to enjoy life. Traditional doctors give you two choices. Go under the knife or you take Big Pharma’s drugs. Either way, you have a good chance of ending up with your manhood on the line… If you have surgery, there’s a big risk you’ll be saying goodbye to your sex life for good. The rate of impotence is a shocking 50 to 60% after prostate surgery.1 Big Pharma’s meds to shrink your prostate are no better. These sy...
Source: Al Sears, MD Natural Remedies - October 19, 2017 Category: Complementary Medicine Authors: Cathy Card Tags: Anti-Aging Source Type: news

Fatty Liver Disease Fastest-growing Reason for Transplants in Young U.S. Adults Fatty Liver Disease Fastest-growing Reason for Transplants in Young U.S. Adults
Nonalcoholic fatty liver disease and its more aggressive form, nonalcoholic steatohepatitis, have become the fastest-growing reasons for liver transplants in young Americans, according to a recent study.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - October 18, 2017 Category: Surgery Tags: Gastroenterology News Source Type: news

Fatty liver disease fastest-growing reason for transplants in young U.S. adults
(Reuters Health) - Nonalcoholic fatty liver disease and its more aggressive form, nonalcoholic steatohepatitis, have become the fastest-growing reasons for liver transplants in young Americans, according to a recent study. (Source: Reuters: Health)
Source: Reuters: Health - October 17, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Progress in Fatty Liver and Pediatric Liver Disease Progress in Fatty Liver and Pediatric Liver Disease
New findings on nonalcoholic steatohepatitis, pediatric liver diseases, hepatitis B, and the microbiome will be among the topics tackled at the upcoming Liver Meeting.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 11, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Too Much Sugar Can Harm Livers of Even Healthy Men
Study found an unhealthy buildup of fat in the vital organ when men switched to high-sugar diet Source: HealthDay Related MedlinePlus Pages: Carbohydrates, Fatty Liver Disease, Men's Health (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - October 6, 2017 Category: Consumer Health News Source Type: news

Medical News Today: High-sugar diets raise heart disease risk in healthy people
A study finds that a high-sugar diet changes a healthy person's fat metabolism so that it resembles that of someone with non-alcoholic fatty liver disease. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 6, 2017 Category: Consumer Health News Tags: Cardiovascular / Cardiology Source Type: news

Stop Your Body Attacking Itself
Modern medicine has no cure for autoimmune diseases — and, sadly, most doctors don’t understand them. I’m talking about disorders like rheumatoid arthritis, type 1 diabetes, lupus, fibromyalgia, chronic fatigue syndrome, psoriasis, multiple sclerosis (MS) and more. In all, there are about 80 autoimmune diseases affecting organs throughout the body. They occur when your own immune system becomes overactive and attacks your body instead of diseases and foreign invaders. The standard mainstream treatment for most autoimmune disorders relies on Big Pharma drugs that cover up symptoms or suppress your immun...
Source: Al Sears, MD Natural Remedies - October 5, 2017 Category: Complementary Medicine Authors: Al Sears Tags: Anti-Aging Source Type: news

Worse than liquor for your liver
Most people think liver disease only happens to alcoholics. But the truth is that being overweight or obese actually puts you at a much higher risk for liver damage than alcohol. In fact, alcohol contributes to only 6% of liver damage. But obesity contributes to 52% of liver disease. And if you’re obese, you’re 400% more likely to develop liver damage than a normal-weight individual.1 That’s why about 30% of people in America have some form of chronic fatty liver disease. It’s called non-alcoholic fatty liver disease (NAFLD). NAFLD causes painful swelling and scarring of the liver.  And I blame...
Source: Al Sears, MD Natural Remedies - October 5, 2017 Category: Complementary Medicine Authors: Al Sears Tags: Health Weight Loss Source Type: news

Diabetes diet: Eating THIS could irreversibly HARM liver as well as cause type 2 diabetes
DIABETES is known to be driven by fructose sugar that ’s often added to processed foods. Now new research has found fructose could also cause fatty liver disease. (Source: Daily Express - Health)
Source: Daily Express - Health - October 5, 2017 Category: Consumer Health News Source Type: news

GM soybean oil leads to less obesity and insulin resistance but is still harmful to liver
According to a study, published inNature Scientific Reports, although a genetically-modified soybean oil was associated with lower risk of obesity and insulin resistance, it did not have beneficial effects on risk of diabetes or fatty liver disease.Science Daily (Source: Society for Endocrinology)
Source: Society for Endocrinology - October 4, 2017 Category: Endocrinology Source Type: news

GM soybean oil causes less obesity and insulin resistance but is harmful to liver function
(University of California - Riverside) Researchers at the University of California, Riverside have tested a genetically-modified soybean oil used in restaurants and found that while it induces less obesity and insulin resistance than conventional soybean oil, its effects on diabetes and fatty liver are similar to those of conventional soybean oil, the major vegetable cooking oil used in the United States, with popularity on the increase worldwide. The study also compares the GM soybean oil to coconut and olive oils. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 2, 2017 Category: International Medicine & Public Health Source Type: news

Rosetrees Trust Interdisciplinary Prize awarded to Hebrew University scientists
(The Hebrew University of Jerusalem) The Rosetrees Trust Interdisciplinary Prize for 2017 has been awarded to two scientists from the Hebrew University of Jerusalem, Prof. Yaakov Nahmias and Prof. Nir Friedman, for their research proposal to engineer a platform that mimics the physiological dynamics of human metabolism. The research will be instrumental to drug development, offering a route to the rational design of therapeutics for obesity, fatty liver disease and type 2 diabetes. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 18, 2017 Category: International Medicine & Public Health Source Type: news

Medical News Today: Do you have diabetes, liver disease? Watch out for CVD
A new study shows that non-alcoholic fatty liver disease puts people with type 2 diabetes at a much higher risk of cardiovascular disease and death. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 13, 2017 Category: Consumer Health News Tags: Diabetes Source Type: news

Trigger for fatty liver in obesity
(University of Zurich) Morbid obesity affects the liver: almost one-third of all adults suffer from chronic fatty liver disease, which can lead to infections and even trigger cancer. Researchers at the University Children's Hospital Zurich and the University of Zurich have now found a signaling pathway in cells that play an important role in the development of fatty liver disease. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - September 7, 2017 Category: Cancer & Oncology Source Type: news

Heart Benefit of Alcohol Not Seen in NAFLD Heart Benefit of Alcohol Not Seen in NAFLD
Light to moderate drinkers may have a lower risk of heart disease than teetotalers, but a new study suggests this doesn't hold true in non-alcoholic fatty liver disease (NAFLD).Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - September 7, 2017 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Heart benefit of alcohol not seen in people with liver disease
(Reuters Health) - Light to moderate drinkers may have a lower risk of heart disease than teetotalers, but a new study suggests this doesn ’t hold true for people with fatty liver disease. (Source: Reuters: Health)
Source: Reuters: Health - September 4, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Nonalcoholic Fatty Liver Disease Epidemic Increasing Greatly Nonalcoholic Fatty Liver Disease Epidemic Increasing Greatly
The burden of nonalcoholic fatty liver disease (NAFLD) is increasing greatly, and the need for liver transplants is likely to outstrip the supply of donors, researchers report.Reuters Health Information (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - August 31, 2017 Category: Transplant Surgery Tags: Gastroenterology News Source Type: news

Enzyme produced in the liver promotes obesity, fatty liver disease and insulin resistance
In mice given a high fat diet, an increased production of the enzyme DPP4 by the liver promotes an increase in body fat, the development of fatty liver disease and insulin resistance. According to the study, published in Molecular Metabolism, DPP4 production is therefore a cause rather than result of fatty liver and insulin resistance.Science Daily  (Source: Society for Endocrinology)
Source: Society for Endocrinology - August 25, 2017 Category: Endocrinology Source Type: news

Heart hormones protect against obesity and insulin resistance
(Sanford-Burnham Prebys Medical Discovery Institute) By fleshing out how one signaling receptor contributes to causing obesity through its activity in fatty tissue but not in muscle cells, SBP scientists have zeroed in on an important new avenue of exploration for combating metabolic disease. More than one-third of American adults are considered to be obese, which dramatically increases their risk for developing type 2 diabetes, non-alcoholic fatty liver disease, high blood pressure, and multiple inflammatory conditions. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 25, 2017 Category: International Medicine & Public Health Source Type: news

Enzyme produced in the liver promotes obesity, fatty liver disease and insulin resistance
(Deutsches Zentrum fuer Diabetesforschung DZD) In mice that are given a high-fat diet, an increased production of the enzyme DPP4* by the liver promotes an increase in body fat, the development of fatty liver disease and insulin resistance. These were the findings of a current study by DZD-researchers in Potsdam and T ü bingen. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 24, 2017 Category: International Medicine & Public Health Source Type: news

Fatty liver can cause damage to other organs
NAFLD increases the risk of chronic liver disease, type 2 diabetes and cardiovascular diseases by releasing glucose, fats and proteins into the bloodstream, according to research published inScientific Reports. The secreted substances trigger reactions in other organs, causing further damage. Science Daily (Source: Society for Endocrinology)
Source: Society for Endocrinology - August 22, 2017 Category: Endocrinology Source Type: news

Your NEJM Group Today: Migraine Clinical Pearls / Alcohol Intake in Nonalcoholic Fatty Liver Disease / Okla. Primary Care Opportunity (FREE)
By the Editors Take a look at today's offering from NEJM Group:NEJM Resident 360: Clinical Pearls: Are … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - August 22, 2017 Category: Primary Care Source Type: news

Fatty liver disease: Complex condition can also damage other organs
NON-ALCOHOLIC fatty liver disease is a condition usually seen in people who are obese or overweight. (Source: Daily Express - Health)
Source: Daily Express - Health - August 21, 2017 Category: Consumer Health News Source Type: news

Organ crosstalk: Fatty liver can cause damage to other organs
(Deutsches Zentrum fuer Diabetesforschung DZD) Scientists of the German Center for Diabetes Research (DZD) in T ü bingen discovered that a fatty liver can cause damage to other organs. In two just-published studies they demonstrate the effects of fatty liver disease on the function of the hormone-producing islet cells in the pancreas and on renal function. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 18, 2017 Category: International Medicine & Public Health Source Type: news