AI plus CT improves liver steatosis assessment
Artificial intelligence (AI) used with contrast-enhanced abdominal CT makes...Read more on AuntMinnie.comRelated Reading: Can AI screen for nonalcoholic fatty liver disease? Ultrasound useful for evaluating liver steatosis MRI offers view of liver fat loss in obese patients Steatosis complicates MR elastography for liver fibrosis AIUM: Can deep learning classify liver fibrosis on US? (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - September 22, 2020 Category: Radiology Source Type: news

MAFLD Is Associated With Severity of Covid-19 MAFLD Is Associated With Severity of Covid-19
Does the co-occurence of metabolic-associated fatty liver disease in patients with COVID-19 increase the risk of severe disease?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 21, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

CNIC researchers discover a mechanism allowing immune cells to regulate obesity
(Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)) A CNIC's team have discovered a mechanism explaining how macrophages regulate obesity. The results published in Nature Metabolism could be useful to design new treatments for the obese and overweight, and for some associated pathologies, including fatty liver disease and type 2 diabetes. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - September 17, 2020 Category: International Medicine & Public Health Source Type: news

How high fructose intake may trigger fatty liver disease
A study suggested that consuming high amounts of fructose may promote non-alcoholic fatty liver disease by damaging the intestinal barrier. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - September 15, 2020 Category: Consumer Health News Source Type: news

Researchers find molecular link between liver disease, insulin resistance
Yale researchers have zeroed in on a molecular link between nonalcoholic fatty liver disease and liver insulin resistance in type 2 diabetes. (Source: Yale Science and Health News)
Source: Yale Science and Health News - September 2, 2020 Category: Universities & Medical Training Source Type: news

Menopause may increase risk for non-alcoholic fatty liver disease
Postmenopausal women may be more likely to develop non-alcoholic fatty liver disease due to a reduction in sex hormones, suggests a study published in Endocrinology.News Medical (Source: Society for Endocrinology)
Source: Society for Endocrinology - August 26, 2020 Category: Endocrinology Source Type: news

New insights into mechanism of therapy to reduce liver fat and prevent fibrosis
(Massachusetts General Hospital) A team led by researchers at Massachusetts General Hospital (MGH) has taken an important step forward in the goal of developing a potential treatment for non-alcoholic fatty liver disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 26, 2020 Category: International Medicine & Public Health Source Type: news

Excessive fructose consumption may cause a leaky gut, leading to fatty liver disease
(University of California - San Diego) Researchers at University of California San Diego School of Medicine report that fructose only adversely affects the liver after it reaches the intestines, where the sugar disrupts the epithelial barrier protecting internal organs from bacterial toxins in the gut (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 24, 2020 Category: International Medicine & Public Health Source Type: news

Is turning back the clock in aging fat cells a remedy for lifestyle diseases?
(Osaka University) Researchers from Osaka University found that lifestyle diseases such as diabetes, high cholesterol, and fatty liver are caused by age-related changes in fat cells. Loss of a protein called Rubicon in aged adipocytes allows intracellular degradation processes to kick into overdrive, disrupting normal cellular function and causing the onset of lifestyle diseases. By inhibiting this degradation and restoring a more youthful cellular environment, we may be able to prevent the onset of lifestyle diseases. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - August 18, 2020 Category: International Medicine & Public Health Source Type: news

TGen review suggests postmenopausal women at risk for nonalcoholic fatty liver disease
(The Translational Genomics Research Institute) NAFLD is the most common cause of liver damage, and can lead to liver cirrhosis and death. It affects nearly 1 in 4 people across the globe. It often is associated with obesity, abnormally high amounts of lipids in the blood, and type 2 diabetes. In the US, the number of NAFLD cases is expected to grow to more than 100 million within the next decade, annually costing an estimated at $292 billion. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 14, 2020 Category: International Medicine & Public Health Source Type: news

NAFLD May Predict Arrhythmia Recurrence Post-AF Ablation NAFLD May Predict Arrhythmia Recurrence Post-AF Ablation
The presence of nonalcoholic fatty liver disease adds a further modifiable target for preablation medical optimization, researchers say.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - August 14, 2020 Category: Cardiology Tags: Cardiology News Source Type: news

Fatty liver disease despite a normal weight
(University of Tsukuba) Researchers from the University of Tsukuba found significant differences in the clinical presentation of non-obese patients with non-alcoholic fatty liver disease (NAFLD) based on their sex and body mass index. They found that non-obese NAFLD patients had lower muscle mass and strength (pre-sarcopenia) compared to obese NAFLD patients. Further, fat accumulation in muscles was more common among women. These findings help us understand the clinical presentation of NAFLD. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 3, 2020 Category: International Medicine & Public Health Source Type: news

Insight on novel genetic approaches to metabolic liver diseases
(Wayne State University - Office of the Vice President for Research) Faculty from Wayne State University's Eugene Applebaum College of Pharmacy and Health Sciences are leading a team of researchers to understand the causal relationships between diabetes, obesity and nonalcoholic fatty liver disease in hopes of developing a treatment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 31, 2020 Category: International Medicine & Public Health Source Type: news

Limp handshake? You may be at risk of a potentially fatal liver disease
While social distancing means it's currently barred, new research has revealed that a limp handshake or a weak grip could be an early warning sign of non-alcoholic fatty liver disease. (Source: the Mail online | Health)
Source: the Mail online | Health - July 14, 2020 Category: Consumer Health News Source Type: news

Doctors call fatty liver disease a growing public health concern in Canada
Doctors are warning that soaring rates of a common, but often undetected, liver disease could impose an enormous burden on Canadian health care over the next decade if there isn't more public awareness. (Source: CBC | Health)
Source: CBC | Health - July 13, 2020 Category: Consumer Health News Tags: News/Health Source Type: news

In race to defeat fatty liver disease, Peninsula biotech lines up next clinical trial
In the race to find a drug for the fatty liver disease NASH, George Kemble isn ’t dissuaded by Sagimet Biosciences’ size; it’s the data that count. And after pivots by the San Mateo company that Kemble heads, it has promising early data back from a mid-stage study of its drug targeting nonalcoholic steatohepatitis, or NASH, and plans to take the drug into another mid-st age study early next year. The Phase II study results come as larger companies have released promising data of their own.… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - July 11, 2020 Category: Pharmaceuticals Authors: Ron Leuty Source Type: news

In race to defeat fatty liver disease, Peninsula biotech lines up next clinical trial
In the race to find a drug for the fatty liver disease NASH, George Kemble isn ’t dissuaded by Sagimet Biosciences’ size; it’s the data that count. And after pivots by the San Mateo company that Kemble heads, it has promising early data back from a mid-stage study of its drug targeting nonalcoholic steatohepatitis, or NASH, and plans to take the drug into another mid-st age study early next year. The Phase II study results come as larger companies have released promising data of their own.… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - July 11, 2020 Category: Biotechnology Authors: Ron Leuty Source Type: news

Researchers find promising therapy to fight epidemic of liver disease
(University of Colorado Anschutz Medical Campus) In an effort to combat a growing worldwide epidemic of Nonalcoholic Fatty Liver Disease (NAFLD), scientists have discovered a new target and a new therapy that has shown promising results in preclinical mouse models, according to researchers at the University of Colorado Anschutz Medical Campus. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 8, 2020 Category: Biology Source Type: news

U of SC: How non-alcoholic fatty liver disease causes Alzheimer's-like neuroinflammation
(University of South Carolina) Research from UofSC associate professor Saurabh Chatterjee's laboratory in Environmental Health Sciences at the Arnold School of Public Health has revealed the cause behind the previously established link between non-alcoholic fatty liver disease and neurological problems. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 6, 2020 Category: International Medicine & Public Health Source Type: news

Tamoxifen-related NAFLD: Prevalence, Incidence, Risk Factors Tamoxifen-related NAFLD: Prevalence, Incidence, Risk Factors
How common is the development of fatty liver after tamoxifen treatment in breast cancer patients, and what are the associated risk factors?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 3, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

The gut shields the liver from fructose-induced damage
(University of Pennsylvania School of Medicine) After one consumes food or a beverage containing fructose, the gastrointestinal system, or gut, helps to shield the liver from damage by breaking down the sugar before it reaches the liver, according to a new multi-center study. However, the consumption of too much fructose--particularly in a short period of time--can overwhelm the gut, causing fructose to " spill over " into the liver, where it wreaks havoc and causes fatty liver, researchers discovered. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 29, 2020 Category: International Medicine & Public Health Source Type: news

Curb the symptoms of non-alcoholic fatty liver disease by adopting a Mediterranean diet
(Natural News) Multiple studies have found that eating more fish and plant-based foods like fruits, vegetables and whole grains — typical components of the Mediterranean diet — contribute to good health even in old age. According to Harvard Medical School researchers, people who stick to a Mediterranean diet have a 46 percent higher chance of healthy... (Source: NaturalNews.com)
Source: NaturalNews.com - June 26, 2020 Category: Consumer Health News Source Type: news

Fatty liver sufferers more likely to be hospitalised with Covid-19, study found
FATTY liver disease is a major risk factor for potentially deadly complications of coronavirus, a groundbreaking new study shows. (Source: Daily Express - Health)
Source: Daily Express - Health - June 21, 2020 Category: Consumer Health News Source Type: news

Novel antisense drug shows promise in slowing fatty liver disease
(University of California - San Diego) A first-in-class clinical trial suggests a novel treatment measurably slowed progression of non-alcoholic fatty liver disease to its more progressive and deadly form. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 16, 2020 Category: International Medicine & Public Health Source Type: news

Risk for Maternal, Neonatal Complications Increased With NAFLD
TUESDAY, June 9, 2020 -- Women with non-alcoholic fatty liver disease (NAFLD) have increased risks for maternal and neonatal complications, according to a study published online June 9 in the Journal of Hepatology. Monika Sarkar, M.D., from the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 9, 2020 Category: Pharmaceuticals Source Type: news

Fecal transplants show promise as treatment for non-alcoholic fatty liver disease
(Lawson Health Research Institute) A new study from Lawson Health Research Institute and Western University suggests that fecal transplants could be used as a treatment for non-alcoholic fatty liver disease (NAFLD). The randomized controlled trial published in The American Journal of Gastroenterology found that fecal transplants in patients with NAFLD result in a reduction in how easily pathogens and other unwanted molecules pass through the human gut and into circulation, known as intestinal permeability. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 9, 2020 Category: International Medicine & Public Health Source Type: news

Mediterranean diet found to ameliorate symptoms of nonalcoholic fatty liver disease
In this study, Greek researchers investigated the effects of the Mediterranean diet (MedDiet) on the clinical, biochemical and inflammatory profile of patients with simple liver steatosis. Their results were published in the Journal of Medicinal Food. Diet is a modifiable key factor and target for the prevention or management of non-alcoholic fatty liver disease (NAFLD).... (Source: NaturalNews.com)
Source: NaturalNews.com - June 2, 2020 Category: Consumer Health News Source Type: news

An imbalance of electrons in the liver may be a common risk factor for disease
(Massachusetts General Hospital) Researchers at Massachusetts General Hospital have uncovered an unexpected connection between an imbalance of electrons in liver cells and many metabolic problems that increase the risk for conditions such as cardiovascular disease and fatty liver disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 28, 2020 Category: International Medicine & Public Health Source Type: news

Modified Parkinson's drug shows potential in treating nonalcoholic fatty liver disease
(GIST(Gwangju Institute of Science and Technology)) Nonalcoholic fatty liver disease (NAFLD) severely impairs the quality of life in patients and often leads to various liver complications. Recently, scientists at Gwangju Institute of Science and Technology designed a novel compound that can potentially treat NAFLD by targeting peripheral serotonin, which regulates lipid metabolism in the liver. They achieved this by structurally modifying an existing neurological drug such that it targets peripheral serotonin by minimizing brain penetration. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - May 28, 2020 Category: Biology Source Type: news

More Severe COVID-19 in Patients With Liver Fibrosis More Severe COVID-19 in Patients With Liver Fibrosis
Patients with non-alcoholic fatty liver disease (NAFLD) and increased liver-fibrosis scores experience more severe illness from COVID-19, according to a study of Chinese patients.Reuters Health Information (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - May 26, 2020 Category: Intensive Care Tags: Gastroenterology News Source Type: news

High Rate of Fatty Liver Disease Found in 9/11 Responders High Rate of Fatty Liver Disease Found in 9/11 Responders
The risk for nonalcoholic fatty liver disease appears to be elevated in 9/11 first responders in New York City, new research shows.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 22, 2020 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Navigating nonalcoholic fatty liver disease (NAFLD)
(American Gastroenterological Association) Gastroenterology, the official journal of the American Gastroenterological Association (AGA), has released a special issue providing clinicians and researchers an up-to-date resource on the risk factors, natural history, diagnosis and treatment of nonalcoholic fatty liver disease (NAFLD). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 19, 2020 Category: International Medicine & Public Health Source Type: news

High Clinical Burden Associated With Nonalcoholic Fatty Liver Disease
WEDNESDAY, May 6, 2020 -- The clinical burden associated with nonalcoholic fatty liver disease (NAFLD) is high, according to a study published online May 5 in Alimentary Pharmacology and Therapeutics. Rohit Loomba, M.D., from the University of... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 6, 2020 Category: Pharmaceuticals Source Type: news

Non-caloric sweetener reduces signs of fatty liver disease in preclinical research study
(Children's Hospital Los Angeles) Children's Hospital Los Angeles investigator shows that non-caloric sweetener stevia decreases signs of fatty liver disease in a pre-clinical model. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 5, 2020 Category: International Medicine & Public Health Source Type: news

Different kinds of white fat are important in disease
(Joslin Diabetes Center) Body fat is linked to many different conditions beyond diabetes. This research could be important for understanding the risk factors for other metabolic diseases, such as fatty liver disease and atherosclerosis, and even non-metabolic diseases that are increased by obesity, such as cancer and Alzheimer's disease. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - May 4, 2020 Category: Biology Source Type: news

Light-to-Moderate Alcohol Consumption Tied to Increased Type 2 Diabetes Risk With NAFLD Light-to-Moderate Alcohol Consumption Tied to Increased Type 2 Diabetes Risk With NAFLD
People with nonalcoholic fatty liver disease are at increased risk of developing type 2 diabetes when they consume light-to-moderate amounts of alcohol than when they abstain from drinking, a Chinese study suggests.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 1, 2020 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Study finds highly elevated levels of fatty liver disease for 9/11 first responders
(Digestive Disease Week) Toxin exposure appears to have contributed to dramatically higher rates of fatty liver disease among first responders to the attack on the World Trade Center on Sept. 11, 2001, according to research that was selected for presentation at Digestive Disease Week ® (DDW) 2020. DDW ® data will be published in the May online supplements to Gastroenterology and GIE: Gastrointestinal Endoscopy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 30, 2020 Category: International Medicine & Public Health Source Type: news

Diet Quality and Its Association With NAFLD and Mortality Diet Quality and Its Association With NAFLD and Mortality
This study investigated the impact of diet on non-alcoholic fatty liver disease. Can a high quality diet lower risk of cancer-related and all-cause mortality?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 29, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Sugar, Fat, Alcohol … What’s Worse for the Liver?
This webinar will investigate the increasing mortality rates of liver disease in the UK associated with obesity and the excess consumption of alcohol. It will give an overview of non-alcoholic fatty liver disease (NAFLD), which is now the most common  of liver disease affecting an estimated 25-30% of adults and 10% of children in the UK and worldwide. Both NAFLD and alcohol-related fatty liver can progress to severe liver disease including fibrosis, cirrhosis and hepatocellular carcinoma. The roles of genetics, obesity and dietary patterns i n the development and progression of liver disease will be dis...
Source: The Nutrition Society - April 9, 2020 Category: Nutrition Authors: Jade Mitchell Source Type: news

Potential early biomarker to track development of non-alcoholic fatty liver disease
(Joslin Diabetes Center) Research from Rohit N. Kulkarni's lab at Joslin Diabetes Center has uncovered a biomarker in humans tied to the development of Non-Alcoholic Fatty Liver Disease that might help doctors detect early stages of the disease. The researchers also determined that this biomarker, a protein known as 'neuronal regeneration related protein' (or NREP), plays a significant role in the regulation of a pathway that is currently being reviewed in clinical trials as a treatment option for the disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 6, 2020 Category: International Medicine & Public Health Source Type: news

Liver Cancer Increase Driven Mainly by NASH in Men Over 60 Liver Cancer Increase Driven Mainly by NASH in Men Over 60
The global increase in liver cancer has been driven mainly by an increase in fatty liver disease in men over 60 in developed countries, suggests a new analysis.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - March 23, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

PCOS Is Associated With NASH Severity and Advanced Fibrosis PCOS Is Associated With NASH Severity and Advanced Fibrosis
Does polycystic ovary syndrome influence severity of non-alcoholic fatty liver disease and risk of advanced fibrosis?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 10, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

AI unlocks screening potential of body CT exams
Artificial intelligence (AI)-based assessment of body composition biomarkers...Read more on AuntMinnie.comRelated Reading: From lab to clinic: How AI can help AI enables screening of fracture risk from CT scans AI spots heart disease on CT lung screening exams AI accurately detects vertebral fractures on CT Can AI screen for nonalcoholic fatty liver disease? (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - March 6, 2020 Category: Radiology Source Type: news

Zydus Cadila gets DCGI nod for world's first drug to treat liver disease
The Ahmedabad-based company said the approved product is the first ever drug anywhere in the world for treatment of Non-Cirrhotic Non-Alcoholic SteatoHepatitis (NASH) which is a progressive disease of the liver. The condition starts with fat accumulation in the liver known as non-alcoholic fatty liver disease and progress to cirrhosis and liver failure. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - March 5, 2020 Category: Pharmaceuticals Source Type: news

Researchers help restore hormonal balance disrupted in metabolic diseases
A new Yale study describes the molecular mechanisms that trigger metabolic imbalance that leads to diabetes and non-alcoholic fatty liver disease. (Source: Yale Science and Health News)
Source: Yale Science and Health News - March 4, 2020 Category: Universities & Medical Training Source Type: news

FDA grants Breakthrough Device Designation for Roche's Elecsys GALAD score to support earlier diagnosis of hepatocellular carcinoma
Basel, 4 March 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Device Designation to the Elecsys ® GALAD score.* This algorithmic score combines gender and age with the biomarker results of the Elecsys AFP, AFP-L3 and PIVKA-II and is intended to aid diagnosis of early stage hepatocellular carcinoma (HCC). Dr. Amit Singal, Medical Director of the Liver Tumor Program   and Clinical Chief of Pathology at UT Southwestern Medical Center in Dallas, USA, stated, " HCC is the fourth leading cause of cancer-related death worldwide, wit...
Source: Roche Investor Update - March 4, 2020 Category: Pharmaceuticals Source Type: news

Low-carb diets transformed these four Britons' lives
Here, we talk to patients with type 2 diabetes, fatty liver disease, and even polycystic ovary syndrome, who have used low-carb diets to tackle their conditions, with life-transforming results. (Source: the Mail online | Health)
Source: the Mail online | Health - March 3, 2020 Category: Consumer Health News Source Type: news

Heart Failure Risk With NAFLD May Be Explained by Obesity Heart Failure Risk With NAFLD May Be Explained by Obesity
The excess weight that causes fatty liver disease also raises a person's risk for heart failure, a recent study suggests.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 28, 2020 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

A compound in five-flavor fruit can protect the liver, says research
(Natural News) Non-alcoholic fatty liver disease (NAFLD) is the name given to a common disorder in which the livers of people who drink little to no alcohol accumulate excess fat. While largely harmless in its early stages, NAFLD can become a serious health problem if it worsens. Therefore, the prevention and treatment of NAFLD is... (Source: NaturalNews.com)
Source: NaturalNews.com - February 28, 2020 Category: Consumer Health News Source Type: news

More Than 4 in 10 Americans Are Now Obese: CDC
Much more than just a cosmetic issue, obesity is associated with type 2 diabetes, heart disease, high blood pressure, stroke, fatty liver disease, sleep apnea, arthritis, gallbladder disease and more, according to the U.S. National Institute for Diabetes and Digestive and Kidney Diseases. (Source: WebMD Health)
Source: WebMD Health - February 27, 2020 Category: Consumer Health News Source Type: news