Mason-based startup founded by UC scientist looking to raise $30M as pressure to move mounts
A Greater Cincinnati startup is planning to significantly grow its capital stack with a planned eight-figure fundraise later this year, and officials are hoping to ring in some Midwest dollars this time around to combat increasing pressures to move the company ’s headquarters to a bigger biotech hub. Amplicore, a Mason-based early-stage biopharma startup developing a new pipeline of drugs to treat musculoskeletal disorders like osteoarthritis, is looking to raise a $30 million Series A by summer.… (Source: bizjournals.com Health Care News Headlines)
Source: bizjournals.com Health Care News Headlines - January 25, 2022 Category: Health Management Authors: Liz Engel Source Type: news

The feasibility and acceptability of a falls prevention e-learning program for physiotherapists - Soh SE, Morgan PE, Hopmans R, Barker AL, Ackerman IN.
OBJECTIVE: To examine the feasibility and acceptability of a falls prevention e-learning program for physiotherapists working with people with osteoarthritis (OA). METHODS: A prospective pre-post quasi-experimental approach was adopted. An e-learni... (Source: SafetyLit)
Source: SafetyLit - January 21, 2022 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Osteoarthritis Phenotyping Makes Progress Osteoarthritis Phenotyping Makes Progress
Karmela Kim Chan, MD, discusses recent efforts to phenotype osteoarthritis, which have not yet been applied successfully to match appropriate treatment to the appropriate patient population.Hospital for Special Surgery (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 20, 2022 Category: Consumer Health News Tags: Rheumatology Commentary Source Type: news

A comparison of balance and fall risk in patients with unilateral and bilateral total knee arthroplasty - T ütüncüler E, Ok N, Güngör HR, Bayrak G, Şavkın R, Büker N.
BACKGROUND: Static or dynamic postural control cannot be fully restored in patients with knee osteoarthritis, even after total knee arthroplasty (TKA), which may contribute to an increased risk of falls in the elderly. OBJECTIVE: To evaluate balanc... (Source: SafetyLit)
Source: SafetyLit - January 12, 2022 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Factors at Midlife May Predict Health Trajectory in Women
Factors linked to health declines include higher BMI, lower level of education, current smoking, osteoarthritis, depression, CVD (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - January 10, 2022 Category: Psychiatry Tags: Cardiology, Endocrinology, Gynecology, Internal Medicine, Oncology, Orthopedics, Psychiatry, Rheumatology, Journal, Source Type: news

Strong relationship of muscle force and fall efficacy, but not of gait kinematics, with number of falls in the year after total hip arthroplasty for osteoarthritis: an exploratory study - Lin XB, Wu WH, Weijer RHA, Prins MR, van Dieen JH, Bruijn SM, Meijer OG.
BACKGROUND: In people with moderate hip osteoarthritis, gait kinematics was reported to be correlated with number of falls in the preceding year. After Total Hip Arthroplasty, subjects generally improve but still fall. The present study explores recovery a... (Source: SafetyLit)
Source: SafetyLit - January 10, 2022 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Factors at Midlife May Predict Health Trajectory in Women
MONDAY, Jan. 10, 2022 -- Factors in women at midlife associated with clinically important declines in physical health and function later in life include body mass index (BMI), educational attainment, smoking, osteoarthritis, clinically significant... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 10, 2022 Category: Pharmaceuticals Source Type: news

Duloxetine Does Not Alleviate Pain in Chronic Osteoarthritis
THURSDAY, Jan. 6, 2022 -- For patients with chronic osteoarthritis (OA) pain, duloxetine added to usual care has no effect compared with usual care alone, according to a study published online Jan. 6 in Arthritis& Rheumatology. Jacoline J. van... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 6, 2022 Category: Pharmaceuticals Source Type: news

Osteoarthritis affects 32.5 million U.S. adults
The degenerative joint disease can be disabling, but there are ways to relieve pain and improve quality of life. (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - January 2, 2022 Category: Consumer Health News Authors: Linda Searing Source Type: news

Lab Notes: Lannett files FDA application for new drug; Virpax to start clinical trial for knee pain drug candidate
Philadelphia-area life sciences news this week includes updates on a potential new drug candidate for diabetes, a topical spray film for knee osteoarthritis, and a medical device for deep vein obstruction. (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - December 23, 2021 Category: Pharmaceuticals Authors: John George Source Type: news

Hyaluronic Acid Injection Use Increased for Knee Osteoarthritis in Seniors
THURSDAY, Dec. 23, 2021 -- The use of hyaluronic acid (HA) injections for knee osteoarthritis in Medicare beneficiaries increased substantially from 2012 to 2018, according to a study published online Dec. 13 in the Journal of Bone& Joint... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 23, 2021 Category: Pharmaceuticals Source Type: news

Increased recurrent falls experience in older adults with coexisting of sarcopenia and knee osteoarthritis: a cross-sectional study - Iijima H, Aoyama T.
BACKGROUND: Sarcopenia and knee osteoarthritis (OA) are two major risk factors for falls in older adults. The coexistence of these two conditions may exacerbate the risk of falls. This cross-sectional study aimed to test the hypothesis that older adults wi... (Source: SafetyLit)
Source: SafetyLit - December 20, 2021 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

It took a pivot, but silk-based products are on the way for startup Cocoon
As an entrepreneur, Ailis Tweed-Kent was well aware that not all startup business models, particularly those in the life sciences, survive the test of time, or the science, or the market. Sure enough, three years after founding Cocoon Biotech Inc., Tweed-Kent and her small team realized that the goal of developing new treatments for osteoarthritis by leveraging silk as a drug-delivery material just wasn’t going to work as planned. But they did discover during their early-stage re search that silk… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - December 15, 2021 Category: Pharmaceuticals Authors: Jay Fitzgerald Source Type: news

Knee symptom but not radiographic knee osteoarthritis increases the risk of falls and fractures: results from the Osteoarthritis Initiative - Cai G, Li X, Zhang Y, Wang Y, Ma Y, Xu S, Shuai Z, Peng X, Pan F.
OBJECTIVE: To describe the effect of knee symptoms and radiographic osteoarthritis (ROA) on the risk of falls, recurrent falls, and fractures. DESIGN: Participants from the Osteoarthritis Initiative were classified as having 'no', 'unilateral' or '... (Source: SafetyLit)
Source: SafetyLit - December 7, 2021 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

Arthritis: Warning signs of osteoarthritis that can be felt, seen and heard in the thumbs
OSTEOARTHRITIS, the most common form of arthritis, is indicative of inflammation in the joints. How can you tell if you have the condition? The warning signs could be discovered in the thumbs. (Source: Daily Express - Health)
Source: Daily Express - Health - December 3, 2021 Category: Consumer Health News Source Type: news

Telehealth Exercise and Diet Programs Curb Pain in Knee Osteoarthritis Telehealth Exercise and Diet Programs Curb Pain in Knee Osteoarthritis
In patients with knee osteoarthritis, telehealth-delivered exercise and diet programs are superior to electronic health information for reducing pain and improving function, a randomized trial shows.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 30, 2021 Category: Consumer Health News Tags: Orthopaedics News Source Type: news

Platelet-Rich Plasma Injections Show No Benefit in Knee OA Platelet-Rich Plasma Injections Show No Benefit in Knee OA
Platelet-rich plasma injections for mild to moderate knee osteoarthritis (OA) show no improvements in pain, function, or cartilage structure, compared with placebo.Medscape Medical News (Source: Medscape Orthopaedics Headlines)
Source: Medscape Orthopaedics Headlines - November 23, 2021 Category: Orthopaedics Tags: Rheumatology News Source Type: news

Arthritis: The plant substance which can slash joint pain by 50% - best supplements
JOINT pain can very much impact day to day living, though fortunately there are several ways which you may be able to relieve it. In older people, joint pain that gets steadily worse is often a sign of osteoarthritis. (Source: Daily Express - Health)
Source: Daily Express - Health - November 16, 2021 Category: Consumer Health News Source Type: news

STEP-KOA knee osteoarthritis programme is cost effective in VA population in the USA
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - November 1, 2021 Category: Drugs & Pharmacology Source Type: news

Self-reported walking difficulty associated with stiff-knee gait in Japanese patients with knee osteoarthritis: a preliminary cross-sectional study - Toda H, Maruyama T, Fujita K, Yamauchi Y, Tada M.
BACKGROUND: Individuals with knee osteoarthritis are restricted in their daily activity because of walking difficulty. The purpose of this investigation was to examine the association between self-reported walking difficulty and knee flexion excursion duri... (Source: SafetyLit)
Source: SafetyLit - October 27, 2021 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

PRP Injections Don't Top Placebo for Ankle Osteoarthritis PRP Injections Don't Top Placebo for Ankle Osteoarthritis
Results from a double-blind, randomized clinical trial provide the first high-level evidence showing a lack of efficacy for platelet-rich plasma injections in the treatment of ankle osteoarthritis.Medscape Medical News (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - October 26, 2021 Category: Internal Medicine Tags: Orthopaedics News Source Type: news

Caring for a Resident With Serious Mental Illness
Mrs. R is an 89-year-old resident with a history of schizophrenia, insulin-dependent diabetes, hypertension, osteoarthritis, osteopenia, vascular dementia, and iron deficiency anemia (underlying cause unknown). She had a hip fracture two years ago and has had a right total hip replacement. She moved into the nursing home after an acute hospital admission for increased confusion and delusional ideation with distorted body image. She believes that her feet and legs are absent and that she cannot walk. (Source: Caring for the Ages)
Source: Caring for the Ages - October 24, 2021 Category: Health Management Authors: Barbara Resnick, Paige Hector Tags: IDT Case Scenario #12 Source Type: news

Knee Osteoarthritis Clinical Trial Design: An Imaging-Based Approach,...
In this free webinar, the featured speakers will discuss the practicality and implementation of common X-ray vs. MRI assessments in knee osteoarthritis clinical trials. Attendees will learn how...(PRWeb October 21, 2021)Read the full story at https://www.prweb.com/releases/knee_osteoarthritis_clinical_trial_design_an_imaging_based_approach_upcoming_webinar_hosted_by_xtalks/prweb18278531.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - October 21, 2021 Category: Pharmaceuticals Source Type: news

An injection of my own blood fixed my agonising knee pain, says Strictly's STEVE BACKSHALL
Steve Backshall was diagnosed with Osteoarthritis which affects around a third of people in the UK aged 45 and over. It happened after his stint on Strictly Come Dancing. (Source: the Mail online | Health)
Source: the Mail online | Health - October 18, 2021 Category: Consumer Health News Source Type: news

The Stumblemeter: design and validation of a system that detects and classifies stumbles during gait - Hartog D, Harlaar J, Smit G.
Stumbling during gait is commonly encountered in patients who suffer from mild to serious walking problems, e.g., after stroke, in osteoarthritis, or amputees using a lower leg prosthesis. Instead of self-reporting, an objective assessment of the number of... (Source: SafetyLit)
Source: SafetyLit - October 15, 2021 Category: International Medicine & Public Health Tags: Distraction, Fatigue, Chronobiology, Vigilance, Workload Source Type: news

Varian Receives FDA "Breakthrough Device Designation" For Embozene(R) Microspheres For Genicular Artery Embolization For Symptomatic Knee Osteoarthritis
PALO ALTO, Calif., Oct. 13, 2021 -- (Healthcare Sales & Marketing Network) -- Varian, a Siemens Healthineers company, announced today that the U.S. Food and Drug Administration (FDA) has granted the company Breakthrough Device Designation for its Embozene... Devices, Interventional, FDA Varian, Embozene, Microspheres, Genicular Artery Embolization, Osteoarthritis (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - October 13, 2021 Category: Pharmaceuticals Source Type: news

DR ELLIE CANNON: Why are my knees aching so badly after I got two new hips?
DR ELLIE CANNON: Today's reader is seeking advice about why their knees are feeling sore having had two hips replaced as they were affected by osteoarthritis. (Source: the Mail online | Health)
Source: the Mail online | Health - October 9, 2021 Category: Consumer Health News Source Type: news

Medical Device Company Pleads Guilty to Dealing in Adulterated Devices, Forfeits Over $800,000 in Non-FDA Approved Devices
FDA OCI, Affordable Healthcare Solutions, sentence, adulterated, medical devices, forfeit, defraud, mislead, unapproved, foreign-market, Supartz Euflexxa, Synvisc, Synvisc-One, Orthovisc, adulterated, hyaluronic acid, (HA), treatment, pain, osteoarthritis, knee, injection, consumer protection, (Source: Office of Criminal Investigations (OCI) Press Releases)
Source: Office of Criminal Investigations (OCI) Press Releases - September 28, 2021 Category: Medical Law Authors: DOJ Source Type: news

Arthritis: The drink that can ‘reverse inflamation’ and offer fast pain relief
ARTHRITIS is a painful condition characterised by swelling in the joints, that can threaten mobility over time. Two of the most widely recognised forms of the condition include rheumatoid arthritis and osteoarthritis. One drink, which can be made at home, may help alleviate symptoms associated with both types of arthritis. (Source: Daily Express - Health)
Source: Daily Express - Health - September 27, 2021 Category: Consumer Health News Source Type: news

The Impact of Osteoarthritis and Surgery on Degeneration of Gluteus Medius Tendon
No abstract available (Source: Lippincott's Bone and Joint Newsletter)
Source: Lippincott's Bone and Joint Newsletter - September 26, 2021 Category: Orthopaedics Tags: CME Article Source Type: news

Osteoarthritis Tied to Risk of Parkinson's Disease
No abstract available (Source: Lippincott's Bone and Joint Newsletter)
Source: Lippincott's Bone and Joint Newsletter - September 26, 2021 Category: Orthopaedics Tags: Perspective Source Type: news

Cannabidiol Found No Better Than Placebo for Hand Arthritis Pain Cannabidiol Found No Better Than Placebo for Hand Arthritis Pain
Patients with hand osteoarthritis or psoriatic arthritis who used cannabidiol as an add-on analgesic had results similar to those of placebo.Medscape Medical News (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - September 16, 2021 Category: Drugs & Pharmacology Tags: Rheumatology News Source Type: news

Early Surgery for Shoulder Instability May Prevent Osteoarthritis Early Surgery for Shoulder Instability May Prevent Osteoarthritis
Other factors, such as obesity, smoking, and manual labor, increase the risk for developing osteoarthritis.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 10, 2021 Category: Consumer Health News Tags: Orthopaedics News Source Type: news

Diet, Exercise in Older Adults With Knee OA Pay Off in Long Term Diet, Exercise in Older Adults With Knee OA Pay Off in Long Term
Older adults with knee osteoarthritis (OA) who participated in a 1.5-year diet and exercise trial continued to see benefits 3.5 years after the interventions ended.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 19, 2021 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Angry bees produce higher quality venom that could help against Parkinson's, osteoarthritis: study
'Angry' honeybees produce better venom than docile ones, a new study says. Experts found there are 99 bee venom proteins and the more protein in the venom, the higher quality it is. (Source: the Mail online | Health)
Source: the Mail online | Health - August 17, 2021 Category: Consumer Health News Source Type: news

Alkem Laboratories launches Ibuprofen, Famotidine tablets in US market
Drug firm Alkem Laboratories on Wednesday announced the launch of Ibuprofen and Famotidine tablets, used to relieve the symptoms of rheumatoid arthritis and osteoarthritis, in the US. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - August 4, 2021 Category: Pharmaceuticals Source Type: news

CartiHeal Announces Pivotal Study Results Demonstrate Agili-C(TM) Superiority to Microfracture and Debridement for the Treatment of Cartilage and Osteochondral Defects
According to a Two-Year Randomized and Controlled Multinational IDE Study KFAR SABA, Israel, Aug. 3, 2021 -- (Healthcare Sales & Marketing Network) -- CartiHeal Ltd, developer of Agili-C™, a proprietary implant for the treatment of cartilage lesions in... Devices, Orthopaedic CartiHeal, Agili-C, osteoarthritis (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - August 3, 2021 Category: Pharmaceuticals Source Type: news

Digital MSK therapy tool Kaia gives equally reliable exercise recommendations as physiotherapists, study finds
The app was able to make suggestions about exercises for patients with  osteoarthritis of the knee or hip.  (Source: mobihealthnews)
Source: mobihealthnews - July 29, 2021 Category: Information Technology Source Type: news

Exergaming to improve balance and decrease the risk of falling in adults with knee osteoarthritis: a mixed-methods feasibility study - Manlapaz DG, Sole G, Jayakaran P, Chapple CM.
BACKGROUND: Exergaming (exercise and gaming) is useful in improving balance in various health conditions, yet there is limited research regarding its application in individuals with knee osteoarthritis (OA). OBJECTIVES: The primary aim of this stud... (Source: SafetyLit)
Source: SafetyLit - July 25, 2021 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

New study pinpoints two separate mutation near GDF5 gene for osteoarthritis, hip dysplasia
(Harvard University) The report details regulatory variants found near a gene, which plays a crucial role joint formation called GDF5. The study pinpoints two separate mutations near the gene, one that can cause knee osteoarthritis in older adults and another that can cause hip dysplasia in babies. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 6, 2021 Category: Biology Source Type: news

A structured treatment model for osteoarthritis appears to be cost effective in Norway
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - July 1, 2021 Category: Drugs & Pharmacology Source Type: news

IOF-ESCEO-SICOT collaboration to enhance educational outreach to to orthopaedic surgeons
(International Osteoporosis Foundation) The International Osteoporosis Foundation (IOF), European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis& Musculoskeletal Diseases (ESCEO) and the International Society of Orthopaedic Surgery and Traumatology (SICOT) have announced a collaborative agreement to mutually develop and expand education and research opportunities. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 30, 2021 Category: International Medicine & Public Health Source Type: news

Improving uniformity and quality of care for people undergoing intra-articular injection
(European Alliance of Associations for Rheumatology) Intra-articular therapies (IAT) are frequently used to treat joint conditions such as gout, rheumatoid arthritis, or osteoarthritis. The procedure involves inserting a needle into the space between the bones of the joint to deliver a medicine. The types of medicines used in IAT techniques vary, from steroids to radiopharmaceuticals. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 24, 2021 Category: International Medicine & Public Health Source Type: news

Are Medicare Beneficiaries With Knee Osteoarthritis Receiving Enough Conservative Care? Are Medicare Beneficiaries With Knee Osteoarthritis Receiving Enough Conservative Care?
Nonsurgical care for knee osteoarthritis is uncommon among older adults, especially in regions of the US where total knee arthroplasty rates are high, a large retrospective analysis shows.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 21, 2021 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Nonsurgical Knee Arthritis Care Varies Geographically
WEDNESDAY, June 16, 2021 -- Nonsurgical osteoarthritis care is associated with lower rates of total knee arthroplasty (TKA) among elderly Americans with knee osteoarthritis, according to a study published online June 8 in Arthritis&... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 16, 2021 Category: Pharmaceuticals Source Type: news

Is my numb big toe a sign of something sinister? DR MARTIN SCURR answers your health questions 
DR MARTIN SCURR: The most likely cause is a trapped nerve close to your big toe - possibly triggered by natural wear in the joint, or osteoarthritis. (Source: the Mail online | Health)
Source: the Mail online | Health - June 15, 2021 Category: Consumer Health News Source Type: news

Osteoarthritis increases Parkinson's risk in older adults, study finds
Older adults with osteoarthritis are at increased risk for developing Parkinson's disease later in life, according to a study published Wednesday by the journal Arthritis Care& Research. (Source: Health News - UPI.com)
Source: Health News - UPI.com - June 9, 2021 Category: Consumer Health News Source Type: news

Osteoarthritis May Be Linked to Increased Risk for Subsequent Parkinson Disease
WEDNESDAY, June 9, 2021 -- Osteoarthritis (OA) may be associated with the risk for developing Parkinson disease (PD), especially among patients with knee or hip OA, according to a study published online June 8 in Arthritis Care&... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 9, 2021 Category: Pharmaceuticals Source Type: news

Study examines care received by patients with knee osteoarthritis
(Wiley) New research reveals that only a minority of U.S. Medicare beneficiaries with knee osteoarthritis in 2005-2010 used non-surgical care such as physical therapy and knee injections, and few were treated by rheumatologists, physiatrists, or pain specialists. The study, which is published in Arthritis& Rheumatology, also found that non-surgical care was more common in regions with low rates of knee replacement surgery. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 9, 2021 Category: International Medicine & Public Health Source Type: news

Osteoarthritis linked to higher Parkinson's disease risk
(Wiley) A study published in Arthritis Care& Research has uncovered an elevated risk of Parkinson's disease in individuals with osteoarthritis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 9, 2021 Category: International Medicine & Public Health Source Type: news