Immunotoxicology Evaluation of Investigational New Drugs
This guidance makes recommendations to sponsors of investigational new drugs (INDs) on (1) the parameters that should be routinely assessed in toxicology studies to determine effects of a drug on immune function, (2) when additional immunotoxicity studies should be conducted, and (3) when additional (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 27, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Antibiotic adverse events on an outpatient parenteral antibiotic service: a retrospective cohort study
Analysis of adverse event data from use of ceftriaxone, ertapenem, daptomycin, teicoplanin, piperacillin/tazobactam and meropenem on an outpatient parenteral antibiotic service shows piperacillin/tazobactam linked to the highest rate of toxicity compared to other antibiotics. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - February 27, 2020 Category: Consumer Health News Source Type: news

Radiation/immunotherapy combo shows promise for recurrent/metastatic head and neck cancers
(American Society for Radiation Oncology) A new phase II trial finds that a combination of radiation therapy and immunotherapy led to encouraging survival outcomes and acceptable toxicity for patients with locally advanced head and neck squamous cell carcinoma (HNSCC). The combination of radiation and pembrolizumab may offer a new treatment option for patients who are ineligible for cisplatin chemotherapy, part of standard treatment for the disease. Findings will be presented at the 2020 Multidisciplinary Head and Neck Cancers Symposium. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 27, 2020 Category: Cancer & Oncology Source Type: news

Women firefighters face high exposure to toxic PFAS chemicals
(University of California - Berkeley) San Francisco's women firefighters are exposed to higher levels of certain toxic PFAS chemicals than women working in downtown San Francisco offices, shows a new study led by researchers at the University of California, Berkeley, the University of California, San Francisco, and Silent Spring Institute. The study represents one of the first published results from the Women Firefighter Biomonitoring Collaborative, a long-term investigation into breast cancer risks faced by women firefighters. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2020 Category: International Medicine & Public Health Source Type: news

Erratum to: Vaping pure cannabidiol e-cigarettes does not produce detectable amount of ∆9-thc in human blood - Kintz P.
This article was originally published with the incorrect title, ``Vaping Pure Vannabidiol e-Cigarettes Does Not Produce Detectable Amount of ∆9-THC in Human Blood.'... (Source: SafetyLit)
Source: SafetyLit - February 26, 2020 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

FDA accepts Roche ’s Biologics License Application for fixed-dose subcutaneous combination of Perjeta and Herceptin for HER2-positive breast cancer
Basel, 25 February 2020 – Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the US Food and Drug Administration (FDA) has accepted the company’s Biologics License Application (BLA) for the fixed-dose combination (FDC) of Perjeta® (pertuzumab) and Herceptin® (trastuzumab) with hyaluronidase, administered by subc utaneous (SC) injection in combination with intravenous (IV) chemotherapy, for the treatment of eligible patients with HER2-positive breast cancer. The BLA for the FDC is based on results from the phase III FeDeriCa study, which demonstrated non-inferior levels of Perjeta in the blood (phar...
Source: Roche Media News - February 25, 2020 Category: Pharmaceuticals Source Type: news

FDA accepts Roche ’s Biologics License Application for fixed-dose subcutaneous combination of Perjeta and Herceptin for HER2-positive breast cancer
Basel, 25 February 2020 – Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the US Food and Drug Administration (FDA) has accepted the company’s Biologics License Application (BLA) for the fixed-dose combination (FDC) of Perjeta® (pertuzumab) and Herceptin® (trastuzumab) with hyaluronidase, administered by subc utaneous (SC) injection in combination with intravenous (IV) chemotherapy, for the treatment of eligible patients with HER2-positive breast cancer. The BLA for the FDC is based on results from the phase III FeDeriCa study, which demonstrated non-inferior levels of Perjeta in the blood (phar...
Source: Roche Investor Update - February 25, 2020 Category: Pharmaceuticals Source Type: news

Suburban areas in flames: Dispersion of potentially toxic elements from burned vegetation and buildings. Estimation of the associated ecological and human health risk - Alexakis DE.
The results of the assessment of burned residential and wildland areas associated with the July 2018 western Attica wildfire are summarised. The dispersion of major and trace elements in a fire impacted suburban landscape which is adjacent in the north wit... (Source: SafetyLit)
Source: SafetyLit - February 24, 2020 Category: International Medicine & Public Health Tags: Burns, Electricity, Explosions, Fire, Scalds Source Type: news

Seminoma: Risk-Adapted Strategy Could Mean Less Toxic Chemo Seminoma: Risk-Adapted Strategy Could Mean Less Toxic Chemo
Early use of FDG-PET in chemotherapy can identify men with low-volume seminoma who have highly chemosensitive disease, enabling them to safely skip the standard chemotherapy regimen   with its toxicity.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 24, 2020 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

USask computer-based simulator tests insects for effects of new pesticide
(University of Saskatchewan) University of Saskatchewan (USask) researchers have used a novel combination of techniques to compare the effects of two families of pesticides used in agriculture, and found that at low dosages the newer pesticide is less toxic than a currently used neonicotinoid one. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 24, 2020 Category: International Medicine & Public Health Source Type: news

The combination of plant-based particles and water forms an 'eco' super-glue
(Aalto University) Plant-based cellulose nanocrystals have remarkable inherent properties, and when combined with water, a powerful adhesive is formed that competes in strength with Superglue, without the need for toxic solvents. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - February 24, 2020 Category: Biology Source Type: news

Odds of culpability associated with use of impairing drugs in injured drivers in Victoria, Australia - Drummer OH, Gerostamoulos D, Di Rago M, Woodford NW, Morris C, Frederiksen T, Jachno K, Wolfe R.
Culpability analysis was conducted on 5000 drivers injured as a result of a vehicular collision and in whom comprehensive toxicology testing in blood was conducted. The sample included 1000 drivers for each of 5 years from approximately 5000-6000 drivers i... (Source: SafetyLit)
Source: SafetyLit - February 22, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

The Global Educational Toxicology Toolkit  (GETKIT): a 1-day course for teaching poisoning essentials in low- and middle-income countries (LMIC): course development and pilot data analysis - Kopec KT, Vohra R, Santos C, Kazzi Z, Wong A.
INTRODUCTION: Worldwide an estimated one million deaths occur annually as a result of poisoning. Internationally there is a lack of toxicology training programs, especially in resource poor settings. We developed a one-day, interactive toxicology curriculu... (Source: SafetyLit)
Source: SafetyLit - February 20, 2020 Category: International Medicine & Public Health Tags: Poisoning Source Type: news

Potential under-recognised risk of harm from the use of propranolol
The Healthcare safety investigation branch (HSIB) hasconducted a patient safety investigation that explores the under recognised toxicity of propranolol in overdose... (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - February 20, 2020 Category: Drugs & Pharmacology Source Type: news

Watching TV helps birds make better food choices
(University of Cambridge) By watching videos of each other eating, blue tits and great tits can learn to avoid foods that taste disgusting and are potentially toxic, a new study has found. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 20, 2020 Category: International Medicine & Public Health Source Type: news

'Stinging Water': Jellyfish Release Toxic Mucus
In this new study, researchers concluded that stinging water is caused by toxin-filled mucus that the jellyfish release into the water. The mucus contains gyrating balls of stinging cells called cassiosomes. (Source: WebMD Health)
Source: WebMD Health - February 19, 2020 Category: Consumer Health News Source Type: news

What's The Source of'Stinging Water'? Jellyfish Release Toxic Mucus
WEDNESDAY, Feb. 19, 2020 -- The mystery of " stinging water " has been solved, scientists say. Stinging water is the seawater near and around upside-down jellyfish (Cassiopea) -- and swimmers can get stinging, itchy skin while submerged in it, even... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 19, 2020 Category: General Medicine Source Type: news

What's Source of'Stinging Water'? Jellyfish Release Toxic Mucus
WEDNESDAY, Feb. 19, 2020 -- The mystery of " stinging water " has been solved, scientists say. Stinging water is the seawater near and around upside-down jellyfish (Cassiopea) -- and swimmers can get stinging, itchy skin while submerged in it, even if... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 19, 2020 Category: General Medicine Source Type: news

Nonclinical Safety Evaluation of the Immunotoxic Potential of Drugs and Biologics Guidance for Industry
Pharmacology / Toxicology (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 19, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

New test identifies poisonous mushrooms
(US Department of Agriculture - Agricultural Research Service) A simple, portable test that can detect the deadliest of the mushroom poisons in minutes has been developed by Agricultural Research Service (ARS) scientists. Eating toxic mushrooms causes more than 100 deaths a year, globally, and leaves thousands of people in need of urgent medical assistance. Amanitin is the class of mushroom toxins that cause the most serious issues. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 19, 2020 Category: International Medicine & Public Health Source Type: news

President Slashes USGS Funding by 24 percent
Under President Trump’s budget request for fiscal year (FY) 2021, the United States Geological Survey (USGS) would be funded at $971.2 million, a 24 percent cut from the FY 2020 level enacted by Congress. The budget once again proposes to consolidate the agency’s seven mission areas into five new mission areas to “better address stakeholder priorities.” The five new mission areas would be: Ecosystems, Energy and Mineral Resources, Natural Hazards, Water Resources, and Core Science Systems. Programs formerly under the Environmental Health area would be moved into the Ecosystems mission area and prog...
Source: Public Policy Reports - February 18, 2020 Category: Biology Authors: AIBS Source Type: news

UCLA researchers discover new compound that promotes lung health
A molecule identified by UCLA researchers helps maintain a healthy balance of cells in airway and lung tissue. If the compound, so far only studied in isolated human and mouse cells, has the same effect in people, it may lead to new drugs to treat or prevent lung cancer.“We think this could help us develop a new therapy that promotes airway health,” said Dr. Brigitte Gomperts, a UCLA professor of pediatrics and of pulmonary medicine, a member of the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA, and lead author of the study. “This could not only inform the treatm...
Source: UCLA Newsroom: Health Sciences - February 18, 2020 Category: Universities & Medical Training Source Type: news

Mesothelioma Detection May Come Earlier with Liquid Biopsy
Cellular Analytics, a biotechnology company in Ontario, Canada, has unveiled a novel liquid biopsy test for mesothelioma that could lead to more effective management of this rare cancer. The test has the potential to produce a much-earlier diagnosis of disease and the ability to personalize treatment and better predict a patient’s response to specific therapies. “We could change completely how this disease is viewed,” Dr. Brent Zanke, a specialist in diagnostic oncology and chief executive officer of Cellular Analytics, told The Mesothelioma Center at Asbestos.com. “It’s a proactive way to get...
Source: Asbestos and Mesothelioma News - February 18, 2020 Category: Environmental Health Authors: Matt Mauney Source Type: news

New study reveals true extent of toxic oil spill from Deepwater Horizon disaster
(Natural News) New research published on Wednesday, February 12, in the journal Science Advances reveals that the Deepwater Horizon oil spill is larger than previous studies showed. The oil spill was found to have spread farther than previously estimated, but it was not discovered until recently because much of the oil was invisible to satellite imagery. The... (Source: NaturalNews.com)
Source: NaturalNews.com - February 18, 2020 Category: Consumer Health News Source Type: news

Characterisation of gunshot residues from non-toxic ammunition and their persistence on the shooter's hands - Roman ò S, De-Giorgio F, D'Onofrio C, Gravina L, Abate S, Romolo FS.
The aim of this work was to characterise three non-toxic ammunition (NTA) from the GECO and Fiocchi brands, which are available in the Italian market. Characterisation was carried out by considering both the elemental chemical composition and morphology, u... (Source: SafetyLit)
Source: SafetyLit - February 17, 2020 Category: International Medicine & Public Health Tags: Violence and Weapons Issues Source Type: news

Air Pollution Can Cross State Lines With Deadly Consequences, Study Finds
(CNN) — Air pollution is known to have negative — even deadly — effects on our health, and studies have shown that breathing pollution can kill, even at levels below air quality guidelines. Now, a new study shows that air pollution produced in one state often blows across state lines, and can contribute to health issues and even premature deaths hundreds of miles away. The study, published Wednesday in the journal Nature, found that, on average, around half of the early deaths in the US linked to pollution actually occur outside the borders of the state where the toxic air originated. “This situatio...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - February 15, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Syndicated CBSN Boston Air Pollution CNN Health News MIT Source Type: news

Novel formulation permits use of toxin from rattlesnake venom to treat chronic pain
(Funda ç ã o de Amparo à Pesquisa do Estado de S ã o Paulo) Researchers Butantan Institute succeeded in reducing the toxicity and potentiating the analgesic effect of crotoxin by encapsulating it in nanostructured silica. The results of tests in an animal model of neuropathic pain are promising. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 14, 2020 Category: International Medicine & Public Health Source Type: news

New Study Shows That When it Comes to Pesticides and Kids, the EPA Has Looked the Other Way
It’s easy to lose count of all of the pesticides that are sprayed on crops in the U.S., and well-nigh impossible to know all of the names (dichloropropene and pyraclostrobin and spinetoram and on and on). But it’s not hard to guess who gets hit hardest by all of these chemicals: kids, whose brain, nervous and hormonal systems are still developing at the time of exposure. What’s more, a new pesticide introduced today will have fewer years to build up in the tissues of, say, a 50-year old, compared to a child who will accumulate a lifetime load of the stuff. That’s the biggest reason that, in 1996, C...
Source: TIME: Science - February 13, 2020 Category: Science Authors: Jeffrey Kluger Tags: Uncategorized Children's Health Environment Environmental Health Pesticides Source Type: news

New Study Shows That When it Comes to Pesticides and Kids, the EPA Has Looked the Other Way
It’s easy to lose count of all of the pesticides that are sprayed on crops in the U.S., and well-nigh impossible to know all of the names (dichloropropene and pyraclostrobin and spinetoram and on and on). But it’s not hard to guess who gets hit hardest by all of these chemicals: kids, whose brain, nervous and hormonal systems are still developing at the time of exposure. What’s more, a new pesticide introduced today will have fewer years to build up in the tissues of, say, a 50-year old, compared to a child who will accumulate a lifetime load of the stuff. That’s the biggest reason that, in 1996, C...
Source: TIME: Health - February 13, 2020 Category: Consumer Health News Authors: Jeffrey Kluger Tags: Uncategorized Children's Health Environment Environmental Health Pesticides Source Type: news

At-risk populations to unintentional and intentional fentanyl and fentanyl+ exposure - Thomas AR, Schwartz RM.
Rising exposure to Fentanyl and Fentanyl + is causing both intentional and unintentional effects. Besides the increasing number of overdoses and deaths from these toxic substances, there are risks for many others such as first responders in law enforcement... (Source: SafetyLit)
Source: SafetyLit - February 12, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Opioid Overdose Deaths In Massachusetts Down 5% From 2016 Peak
BOSTON (AP) — Massachusetts health officials said Wednesday the rate of opioid-related overdose deaths in the state fell an estimated 5% from its 2016 peak. The decline comes despite the growing presence of the synthetic opioid fentanyl as a driver of opioid-related overdose deaths, according to the Massachusetts Department of Public Health. In 2019, the opioid-related overdose death rate was 29 per 100,000 people. In 2016, it was 30.5 per 100,000 people. According to the report, there were 2,023 confirmed and estimated opioid-related overdose deaths in 2019. For the same period in 2016, there were 2,097 confirmed op...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - February 12, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health opioid crisis opioids Source Type: news

Alternative to Alimta Coming for Mesothelioma Patients
The U.S. Food and Drug Administration has granted final approval of Pemfexy, a new brand of the chemotherapy drug pemetrexed, to combat malignant mesothelioma and advanced stage non-small cell lung cancer. The approval will allow oncologists to offer an alternative to Alimta, which today is considered standard pemetrexed and manufactured by Eli Lilly and Company. The chemotherapy drug is designed to block DNA replication and cell division. However, Pemfexy will not be available until February 2022. The FDA approval is limited to pleural mesothelioma patients whose disease is unresectable. Pemfexy is produced by Eagle Pharm...
Source: Asbestos and Mesothelioma News - February 12, 2020 Category: Environmental Health Authors: Matt Mauney Source Type: news

Why sports can be so toxic to boys and how we unravel that culture
For good and ill, organized sports provide boys with what is probably their most influential education on masculinity. (Source: CNN.com - Health)
Source: CNN.com - Health - February 11, 2020 Category: Consumer Health News Source Type: news

Blasting 'forever' chemicals out of water with a vortex of cold plasma
(Drexel University) Researchers from Drexel University have found a way to destroy stubbornly resilient toxic compounds, ominously dubbed 'forever chemicals,' that have contaminated the drinking water of millions across the United States. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 11, 2020 Category: International Medicine & Public Health Source Type: news

Effect of the UK Psychoactive Substances Act 2016 on episodes of toxicity related to new psychoactive substances as reported to the National Poisons Information Service. A time series analysis - Al-Banaa I, Hawkins L, Hill SL, Lupton DJ, Jackson G, Sandilands EA, Bradberry SM, Thompson JP, Rushton S, Thomas SHL.
BACKGROUND: There have been recent increases in use of new psychoactive substances (NPS) associated with acute health harms including hospital presentations due to toxicity and increasing numbers of deaths. In response, the UK Government enacted generic le... (Source: SafetyLit)
Source: SafetyLit - February 11, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Inhalational toxicity of aluminum phosphide as an ongoing concern; a report of two cases - Shafahi A, Mostafazadeh B, Dadpour B.
Acute aluminium phosphide (ALP) poisoning is an extremely lethal poisoning. Ingestion is usually suicidal in intent, uncommonly accidental and rarely homicidal. Unfortunately, the absence of a specific antidote results in very high mortality and the key to... (Source: SafetyLit)
Source: SafetyLit - February 10, 2020 Category: International Medicine & Public Health Tags: Poisoning Source Type: news

Oleander and datura poisoning: an update - Pillay VV, Sasidharan A.
India has a very high incidence of poisoning. While most cases are due to chemicals or drugs or envenomation by venomous creatures, a significant proportion also results from consumption or exposure to toxic plants or plant parts or products. The exact nat... (Source: SafetyLit)
Source: SafetyLit - February 10, 2020 Category: International Medicine & Public Health Tags: Home and Consumer Product Safety Source Type: news

Pyrethroid poisoning - Ramchandra AM, Chacko B, Victor PJ.
INTRODUCTION: Pyrethroid compounds are widely used as insecticides. These compounds not only have a versatile application, but also have favourable toxicological profiles with high selectivity and toxicity to insects and low toxicity to humans. Despite thi... (Source: SafetyLit)
Source: SafetyLit - February 8, 2020 Category: International Medicine & Public Health Tags: Home and Consumer Product Safety Source Type: news

Analysis of deaths by intoxication that occurred in Brazil from 2010 to 2015 based on the Mortality Information System (SIM) - Bochner R, Freire MM.
Many studies analyze the epidemiological profile of deaths caused by a single toxic agent. However, broader mortality analyses can be obtained by evaluating multiple agents over the same period of time. For this purpose, a retrospective descriptive study w... (Source: SafetyLit)
Source: SafetyLit - February 8, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Toxic coal ash is making its way to Florida from Puerto Rico
A law was passed in Puerto Rico to prohibit the deposit and disposal of coal ash on the island. (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - February 7, 2020 Category: Consumer Health News Source Type: news

'It can damage your face': Skin-whitening creams illegally sold in Canada
A Marketplace investigation found illegal skin-whitening products on store shelves across Canada — and the messaging might not be the only thing toxic about them. (Source: CBC | Health)
Source: CBC | Health - February 7, 2020 Category: Consumer Health News Tags: News/Health Source Type: news

'Whiter skin in 14 days': Tracking the illegal sale of skin-whitening creams in Canada
A Marketplace investigation found illegal skin-whitening products on store shelves across Canada — and the messaging might not be the only thing toxic about them. (Source: CBC | Health)
Source: CBC | Health - February 7, 2020 Category: Consumer Health News Tags: News/Health Source Type: news

Roche to present new data on Tecentriq in combination with Avastin that shows improvement in overall survival for Chinese patients with the most common form of liver cancer
Basel, 7 February 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that additional data will be presented from a cohort of Chinese patients in the Phase III IMbrave150 study that evaluated Tecentriq ® (atezolizumab) in combination with Avastin® (bevacizumab) as a treatment for people with unresectable hepatocellular carcinoma (HCC) who have not received prior systemic therapy. Data from 194 Chinese patients who took part in the IMbrave150 study were consistent with the global results, that showed a statistically significant and clinically meaningful improvement in overall survival (OS) and progression-free...
Source: Roche Investor Update - February 7, 2020 Category: Pharmaceuticals Source Type: news

Some U.S. Workers Are Bringing Toxins Home to Their Kids
THURSDAY, Feb. 6, 2020 -- People who work with potentially dangerous chemicals or hazardous metals such as lead may unwittingly bring those toxic substances home, a new review says. In the home, these substances put family members, especially... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 6, 2020 Category: General Medicine Source Type: news

Toxicological property of acetaminophen: the dark side of a safe antipyretic/analgesic drug? - Ishitsuka Y, Kondo Y, Kadowaki D.
Acetaminophen (paracetamol, N-acetyl-p-aminophenol; APAP) is the most popular analgesic/antipyretic agent in the world. APAP has been regarded as a safer drug compared with non-steroidal anti-inflammatory drugs (NSAIDs) particularly in terms of lower risks... (Source: SafetyLit)
Source: SafetyLit - February 6, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Botanical drug is shown to help patients with head and neck cancers
In this study, UCLA researchers found that when APG-157 is taken through oral mucosal absorption, patients have high levels of curcumin circulating in their blood and absorbed by cancer tissues.METHODUCLA researchers conducted the study of APG-157 comparing 12 people who had oral and oropharyngeal cancer with a control group of 13 people who did not have cancer. The reason both the people with cancer and without cancer were part of the study was to show that the drug was not toxic to either people with cancer or those without cancer.The medication was given each hour for three hours and was delivered as a lozenge that slow...
Source: UCLA Newsroom: Health Sciences - February 6, 2020 Category: Universities & Medical Training Source Type: news

FDA Moves Closer to Standardized Testing for Asbestos in Talc
The U.S. Food and Drug Administration moved closer on Tuesday to formulating standardized testing of talc-based products for the presence of toxic asbestos fibers. Experts from eight different federal agencies explained earlier recommendations at a day-long hearing. The session also featured input from 25 members of the public, which included industry representatives, consumer advocates and testing experts. “Standards are needed,” said Dr. Paul Howard, FDA Office of Regulatory Science, during his presentation. “They just don’t exist at this time.” Dr. Linda Katz, director of the FDA Office of ...
Source: Asbestos and Mesothelioma News - February 5, 2020 Category: Environmental Health Authors: Matt Mauney Source Type: news

Not all in-home drinking water filters completely remove toxic PFAS
(Duke University) A new study by scientists at Duke University and North Carolina State University finds that -- while using any drinking water filter is better than using none -- many in-home water filters are only partially effective at removing toxic perfluoroalkyl substances, commonly known as PFAS. A few filters, if not properly maintained, can even increase PFAS contamination. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 5, 2020 Category: International Medicine & Public Health Source Type: news

CD19 CAR NK-cell therapy achieves 73% response rate in patients with leukemia and lymphoma
(University of Texas M. D. Anderson Cancer Center) According to results from a Phase I/IIa trial at The University of Texas MD Anderson Cancer Center, treatment with cord blood-derived chimeric antigen receptor (CAR) natural killer (NK)-cell therapy targeting CD19 resulted in clinical responses in a majority of patients with relapsed or refractory non-Hodgkin's lymphoma (NHL) and chronic lymphocytic leukemia (CLL), with no major toxicities observed. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 5, 2020 Category: Cancer & Oncology Source Type: news

Philadelphia School District Demands Jury Trial For Lead Poisoning Claims
PHILADELPHIA - The School District of Philadelphia on Jan. 17 filed a demand in Pennsylvania federal court for a jury trial in a lawsuit brought by a family that contends that the district is liable for creating a public health crisis by failing to properly inspect an elementary school for toxic lead-based paint (D.P., a minor by his parents and natural guardians v. School District of Philadelphia, No. 19-5799, E.D. Pa.). (Source: LexisNexis® Mealey's™ Emerging Toxic Torts Legal News)
Source: LexisNexis® Mealey's™ Emerging Toxic Torts Legal News - February 5, 2020 Category: Medical Law Source Type: news