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Intoxication caused by new psychostimulants: analytical methods to disclose acute and chronic use of benzofurans and ethylphenidate - Barcel ó B, Gomila I, Rotolo MC, Marchei E, Kyriakou C, Pichini S, Roset C, Elorza MÁ, Busardò FP.
The acute and chronic toxicity of several new psychoactive substances (NPS) is unknown, and only little information is available on the pharmacology and toxicology, toxicokinetics, and detectability in body samples of such new compounds. We here propose an... (Source: SafetyLit)
Source: SafetyLit - July 22, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Treatment methods following suicidal self-administration of IV organophosphate: what can additional lipid administration change? - T ürkdogan KA, Duman A, Avcil M, Akoz A, Canakci SE, Kantekin B.
Organic phosphor compounds are highly toxic and life-threatening compounds that are widely used in agriculture, households and gardens worldwide. While oral intakes are observed frequently, toxic effects can also be seen through contract or inhalation. How... (Source: SafetyLit)
Source: SafetyLit - July 21, 2017 Category: International Medicine & Public Health Tags: Poisoning Source Type: news

Namibia: Namibia Ratifies Ban On Import of Toxic Waste
[New Era] Windhoek -Namibia has joined the rest of the world in the fight against toxic pollution after it ratified the Basel Convection to ban developed countries from dumping hazardous waste in developing countries, whether in solid, liquid or gas form. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - July 21, 2017 Category: African Health Source Type: news

Accuray touts study data in head-to-head between TomoTherapy and Varian ’ s RapidArc
Accuray (NSDQ:ARAY) today released data from a prospective study comparing its TomoTherapy intensity-modulated radiation therapy system with Varian Medical‘s (NYSE:VAR), RapidArc radiotherapy system, touting a higher survival rate for patients treated with its TomoTherapy system. Results from the study were published last month in the International Journal of Radiation Oncology – Biology – Physics. Accuray said that the 166-patient, multi-center study was the 1st to prospectively compare clinical outcomes across radiation platforms. In the study, 74 individuals were treated with the TomoTherapy...
Source: Mass Device - July 20, 2017 Category: Medical Devices Authors: Fink Densford Tags: Clinical Trials Oncology Accuray Inc. Varian Medical Systems Source Type: news

Zika rewrites maternal immunization ethics
(Source: ScienceNOW)
Source: ScienceNOW - July 20, 2017 Category: Science Authors: Cohen, J. Tags: Medicine, Diseases, Pharmacology, Toxicology, Science and Policy, Virology In Depth Source Type: news

Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104
Hsp100 polypeptide translocases are conserved members of the AAA+ family (adenosine triphosphatases associated with diverse cellular activities) that maintain proteostasis by unfolding aberrant and toxic proteins for refolding or proteolytic degradation. The Hsp104 disaggregase from Saccharomyces cerevisiae solubilizes stress-induced amorphous aggregates and amyloids. The structural basis for substrate recognition and translocation is unknown. Using a model substrate (casein), we report cryo–electron microscopy structures at near-atomic resolution of Hsp104 in different translocation states. Substrate interactions ar...
Source: ScienceNOW - July 20, 2017 Category: Science Authors: Gates, S. N., Yokom, A. L., Lin, J., Jackrel, M. E., Rizo, A. N., Kendsersky, N. M., Buell, C. E., Sweeny, E. A., Mack, K. L., Chuang, E., Torrente, M. P., Su, M., Shorter, J., Southworth, D. R. Tags: Biochemistry r-articles Source Type: news

PETA journal article lays out steps to end flea/tick infestation tests on dogs and cats
(People for the Ethical Treatment of Animals) An article just published in the peer-reviewed journal Regulatory Toxicology and Pharmacology, authored by scientists from People for the Ethical Treatment of Animals (PETA), calls on companies to stop testing experimental flea and tick control products on dogs and cats. The article lays out steps that companies can take to make the transition to non-animal test methods. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - July 19, 2017 Category: International Medicine & Public Health Source Type: news

New robotic lab tracking toxicity of Lake Erie algal bloom
(University of Michigan) A new research tool to safeguard drinking water is now keeping a watchful eye on Lake Erie. This week, a robotic lake-bottom laboratory began tracking the levels of dangerous toxins produced by cyanobacteria that bloom each summer in the lake's western basin. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 19, 2017 Category: International Medicine & Public Health Source Type: news

New harmless radiopaque glue to seal bleeding and guide surgery
(Institute for Basic Science) First nanoparticle-based adhesive with imaging contrast effect in CT and ultrasound was successfully tested in animals and showed less toxicity than the FDA-approved glue CA-Lp. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 19, 2017 Category: Biology Source Type: news

Mercedes to recall 3 million diesels over toxic emissions
In a drastic move which casts fresh doubt over the future of diesel engines, German car giant Daimler urged drivers across Europe and the UK to have a ‘software update’ installed. (Source: the Mail online | Health)
Source: the Mail online | Health - July 19, 2017 Category: Consumer Health News Source Type: news

CDK Inhibitors in Breast Cancer: Manageable Toxicity Profile CDK Inhibitors in Breast Cancer: Manageable Toxicity Profile
CDK inhibitors represent a new treatment option in HR+ breast cancer. A new review article shows that their overall toxicity is low and can be adequately managed.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 18, 2017 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Extremely toxic sunscreen ingredients you want to avoid
(Natural News) With summer in full swing, more people are bringing out the staples of the season: grills, pool toys, sunglasses, and of course, sunscreen. The last item is especially important since so many of us rely on sunscreen to protect ourselves from excessive UV radiation. In theory, slathering on a bit of sunscreen should... (Source: NaturalNews.com)
Source: NaturalNews.com - July 18, 2017 Category: Consumer Health News Source Type: news

Evaluating low-dose toxicity from endocrine active chemicals
(National Academies of Sciences, Engineering, and Medicine) A new report by the National Academies of Sciences, Engineering, and Medicine proposes a strategy that the US Environmental Protection Agency (EPA) should use to evaluate the evidence of adverse human health effects from low doses of exposure to chemicals that can disrupt the endocrine system. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 18, 2017 Category: International Medicine & Public Health Source Type: news

Health care vote delay gives foes, supporters more time
Political foes from left and right are using the delayed vote on the Republican health care bill to make it as toxic as possible for wavering GOP senators to support it (Source: ABC News: Health)
Source: ABC News: Health - July 17, 2017 Category: Consumer Health News Tags: Health Source Type: news

What to Do When a Child Has a Toxic Exposure What to Do When a Child Has a Toxic Exposure
A free resource helps clinicians identify and manage toxic exposures in children and improve health outcomes.CDC Expert Commentary (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 17, 2017 Category: Consumer Health News Tags: Pediatrics Commentary Source Type: news

California's declaration means Neil deGrasse Tyson is now pushing a deadly herbicide POISON that kills people
(Natural News) California’s far-left government is running the once prosperous Golden State into the ground, but it showed some semblance of reason by declaring that glyphosate — the toxic chemical found in Monsanto’s prize weed killer, Roundup — is a chemical known to be cancer causing. Under the state’s Office of Environmental Hazard Assessment ruling, California... (Source: NaturalNews.com)
Source: NaturalNews.com - July 17, 2017 Category: Consumer Health News Source Type: news

A new ligand extends the half-life of peptide drugs from minutes to days
Peptides are biological molecules, made up of short sequences of amino acids. Because they are easy to synthesize, show low toxicity and high efficiency, peptides such as insulin and other hormones can be used as drugs. But peptides are quickly cleared by the kidneys, which means that we can only use peptide drugs that act within minutes. This problem can be overcome by connecting peptides to ligands that bind blood-serum proteins such as albumin, allowing the peptide to linger in the bloodstream longer. (Source: World Pharma News)
Source: World Pharma News - July 17, 2017 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

"Food Evolution" movie filmmakers attack one of America's greatest moms, smearing her to push toxic herbicides and GMOs in the name of "science"
(Natural News) Who knows their child the best? For thousands of years, the norm has been two parents who share responsibility for the little ones, with a larger burden placed upon a mother for their daily bread and nurturing. While the current excursions in society and cultural norms have shifted greatly in the past few... (Source: NaturalNews.com)
Source: NaturalNews.com - July 17, 2017 Category: Consumer Health News Source Type: news

Adrenaline Overdose in Pediatric Anaphylaxis: A Case Report Adrenaline Overdose in Pediatric Anaphylaxis: A Case Report
Appropriate administration of adrenaline in pediatric anaphylaxis remains challenging. How does blood pressure help differentiate progression of anaphylaxis symptoms from adrenaline toxicity?Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 17, 2017 Category: Consumer Health News Tags: Pediatrics Journal Article Source Type: news

Space station project seeks to crystallize the means to counteract nerve poisons
(NIH/National Institute of Neurological Disorders and Stroke) The microgravity conditions of the International Space Station (ISS) may hold the key to improving our understanding of how to combat toxic nerve agents such as sarin and VX. That is the hope of Countermeasures Against Chemical Threats (CounterACT) project that is part of an initiative at the National Institutes of Health aimed at developing improved antidotes for chemical agents. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 17, 2017 Category: International Medicine & Public Health Source Type: news

Space station project seeks to crystalize the means to counteract nerve poisons
(NIH/National Institute of Neurological Disorders and Stroke) The microgravity conditions of the International Space Station (ISS) may hold the key to improving our understanding of how to combat toxic nerve agents such as sarin and VX. That is the hope of Countermeasures Against Chemical Threats (CounterACT) project that is part of an initiative at the National Institutes of Health aimed at developing improved antidotes for chemical agents. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 17, 2017 Category: International Medicine & Public Health Source Type: news

Let ’s treat online abuse as a public health hazard | Sonia Sodha
Social media bullying is getting the parliamentary attention it deserves – but politicians must focus on what’s going on behind this toxic behaviourOne of the most important breakthroughs in public health came in1847, when a Hungarian doctor, Ignaz Semmelweis, discovered that surgeons could dramatically cut mortality rates by disinfecting their hands. At the time, he was ridiculed by his medical contemporaries. But today, hand washing remains the cornerstone of lifesaving medical hygiene.I wonder if we ’ve got something important to learn from Semmelweis when it comes to online abuse. Last week, MPs debat...
Source: Guardian Unlimited Science - July 16, 2017 Category: Science Authors: Sonia Sodha Tags: Cyberbullying Internet Society NSPCC whistleblowing advice line: in focus Medical research Science Source Type: news

PCR-based method for the detection of toxic mushrooms causing food-poisoning incidents - Nomura C, Masayama A, Yamaguchi M, Sakuma D, Kajimura K.
In this study, species-specific identification of five toxic mushrooms, Chlorophyllum molybdites, Gymnopilus junonius, Hypholoma fasciculare, Pleurocybella porrigens, and Tricholoma ustale, which have been involved in food-poisoning incidents in Japan, was... (Source: SafetyLit)
Source: SafetyLit - July 16, 2017 Category: International Medicine & Public Health Tags: Home and Consumer Product Safety Source Type: news

Agent clears toxic proteins and improves cognition in neurodegeneration models
(Georgetown University Medical Center) Researchers have found cell receptors abnormally overexpressed in post-mortem brains of those with Parkinson's and Alzheimer's diseases, and that they can be inhibited in animal models to clear toxic protein buildup, reduce brain inflammation, and improve cognitive performance. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - July 16, 2017 Category: International Medicine & Public Health Source Type: news

Precision Medicine in Metastatic Colorectal Cancer: Relevant Carcinogenic Pathways and Targets —PART 1: Biologic Therapies Targeting the Epidermal Growth Factor Receptor and Vascular Endothelial Growth Factor
Here we review drugs that target the EGFR and VEGF pathways, focusing on patient selection, drug toxicities, and how to choose agents for first-line therapy. (Source: CancerNetwork)
Source: CancerNetwork - July 15, 2017 Category: Cancer & Oncology Authors: Benjamin A. Weinberg, MD Marion L. Hartley, PhD Mohamed E. Salem, MD Tags: Colorectal Cancer Gastrointestinal Cancer Oncology Journal Review Article Source Type: news

Forensic aspects of homicides by insulin overdose - Tong F, Wu R, Huang W, Yang Y, Zhang L, Zhang B, Chen X, Tang X, Zhou Y.
Analysis of homicidal insulin overdose is a challenging task in forensic practice because of the difficulties in toxicological analysis as well as the elusive pathologic changes. We performed a detailed histopathologic examination on four autopsy cases inv... (Source: SafetyLit)
Source: SafetyLit - July 15, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Fighting TB with Open-Source Tech
VideoFighting TB with Open-Source TechJuly 14, 2017EndTB (Expand New Drug markets for Tuberculosis) is a comprehensive international project that aims to find shorter, less toxic, oral-only, and more effective treatments for TB.Read more about how MSF is helping patients get access to new TB drugs.   (Source: MSF News)
Source: MSF News - July 14, 2017 Category: International Medicine & Public Health Authors: Melissa Pracht Source Type: news

Opioid Epidemic Resources from NLM
The National Library of Medicine has created a number of portals and lists with numerous resources on opioid abuse, addiction, and treatment. Diverse Populations – Public, Multiple Languages, and Healthcare Professionals (Outreach and Specific Populations Branch bulletin, 2017-05-10) Opiate Addiction and Treatment Portal (SIS Environmental Health and Toxicology) Response to the opioid epidemic – includes those listed in the Diverse Populations link as well as several other federal sites (DISASTR-OUTREACH-LIB listserv archives) /ch (Source: MCR News)
Source: MCR News - July 14, 2017 Category: Databases & Libraries Authors: liaison Tags: All Members Source Type: news

Course constructions: a case-base of forensic toxicology - Zhou N, Wu Y, Su T, Zhang L, Yin K, Zheng D, Zheng J, Huang L, Wu Q, Cheng J.
Forensic toxicology education in China is limited by insufficient teaching methods and resources, resulting in students with adequate theoretical principles but lacking practice experience. Typical cases used as teaching materials vividly represent intoxic... (Source: SafetyLit)
Source: SafetyLit - July 14, 2017 Category: International Medicine & Public Health Tags: Poisoning Source Type: news

Alcohol and drug toxicology screens at time of hospitalization do not predict PTSD or depression after traumatic injury - McLaughlin C, Kearns NT, Bennett M, Roden-Foreman JW, Roden-Foreman K, Rainey EE, Funk G, Powers MB, Warren AM.
BACKGROUND: Identifying risk factors for the development of PTSD and depression is critical for intervention and recovery after injury. Given research linking toxicology screens and substance use and the evidenced relationship between substance misuse and ... (Source: SafetyLit)
Source: SafetyLit - July 14, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Due to global human pollution, the arctic has become a toxic reservoir of heavy metals, PCBs and other deadly chemicals
(Natural News) Human-induced pollution has greatly affected the Greenland ice sheet and the whole Arctic region over the last few decades. Back in the late 1950s, the U.S. Army Corps of Engineers built Camp Century, an army base located just below the surface of the ice sheet. The cavernous army base, big enough to accommodate up to... (Source: NaturalNews.com)
Source: NaturalNews.com - July 14, 2017 Category: Consumer Health News Source Type: news

Solar panel manufacturing devastates the environment with toxic heavy metals, warns report
(Natural News) Solar energy sounds great in theory doesn’t it? What could possibly be better for the environment than making use of one of Earth’s most abundant natural resources: Sunlight. Plants use sunlight to create energy, and they do so flawlessly. It is no wonder that scientists have been seeking to use the sun as a... (Source: NaturalNews.com)
Source: NaturalNews.com - July 13, 2017 Category: Consumer Health News Source Type: news

Grenfell Tower fire survivor, 12, treated for cyanide poisoning
Medical papers relating to Luana Gomes raise fears highly toxic hydrogen cyanide gas was released when insulation burnedA survivor of the Grenfell Tower fire has been treated for cyanide poisoning, raising fears that the highly toxic gas hydrogen cyanide might have been released by the burning of insulation or plastics during the blaze.Luana Gomes, 12, was diagnosed with smoke inhalation injury and cyanide poisoning, according to discharge papers from King ’s College hospital in London seen by theBBC ’s Newsnight.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - July 13, 2017 Category: Science Authors: Jamie Grierson and Ian Sample Science editor Tags: Grenfell Tower fire UK news London Science Source Type: news

Side effects not a major problem for new class of breast cancer drugs
(Wiley) A ground-breaking new class of oral drugs for treating breast cancer, known as cyclin-dependent kinase (CDK) inhibitors, are generally well-tolerated, with a manageable toxicity profile for most patients. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 13, 2017 Category: International Medicine & Public Health Source Type: news

The Chemicals in Your Mac and Cheese
Macaroni and cheese products were especially high in phthalates, chemicals that may pose special risks to pregnant women and young children. (Source: NYT Health)
Source: NYT Health - July 13, 2017 Category: Consumer Health News Authors: RONI CARYN RABIN Tags: Testosterone Food Cheese Hazardous and Toxic Substances Hormones Babies and Infants Factories and Manufacturing Containers and Packaging Pregnancy and Childbirth Diet and Nutrition Consumer Protection Food Contamination and Poisoning Source Type: news

Surviving the cure
(Source: ScienceNOW)
Source: ScienceNOW - July 13, 2017 Category: Science Authors: Cohen, J. Tags: Medicine, Diseases, Pharmacology, Toxicology, Physiology Feature Source Type: news

Labmade smallpox is possible, study shows
(Source: ScienceNOW)
Source: ScienceNOW - July 13, 2017 Category: Science Authors: Kupferschmidt, K. Tags: Pharmacology, Toxicology, Science and Policy, Virology In Depth Source Type: news

Stress worsens effects of toxic chemical exposure in pregnancy
Researchers at the University of California, Berkeley, found that stress can worsen the effects to the unborn baby from toxic chemical exposure in pregnancy. (Source: Health News - UPI.com)
Source: Health News - UPI.com - July 12, 2017 Category: Consumer Health News Source Type: news

Toxic bacteria often lurk in children ’s, dogs’ sandboxes
(Reuters Health) - Playground sandboxes can harbor deadly - and drug resistant - strains of the diarrhea-causing bacterium Clostridum difficile, research in Spain shows. (Source: Reuters: Health)
Source: Reuters: Health - July 12, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Does Stress Intensify Harms Done By Chemical Exposure in Pregnancy?
WEDNESDAY, July 12, 2017 -- More evidence of stress's harmful effects comes from a pregnancy study. California researchers found that stress increases the risk that exposure to toxic chemicals in pregnancy will lead to a low birth weight baby. " It... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - July 12, 2017 Category: General Medicine Source Type: news

Equashield seeks to automate hazardous drug handling: a Drug Delivery Business News podcast
Equashield’s Jason Dutcher chats with Drug Delivery Business Newseditor Sarah Faulkner about the company’s closed system transfer device and its latest move to automate hazardous drug compounding.  Healthcare workers are often tasked with handling hazardous drugs, which give off harmful vapors. Exposure to these drugs has been linked to severe health risks, including infertility, miscarriage and cancer. To guard workers against exposure to toxic compounds, Equashield has developed a streamlined closed system transfer device for the handling of hazardous drugs. Get the full story at our sister site, Dr...
Source: Mass Device - July 12, 2017 Category: Medical Devices Authors: Sarah Faulkner Tags: Drug-Device Combinations Oncology Pharmaceuticals Robotics equashield Source Type: news

One in four youngsters face risk of deadly toxic stress
'The damage that happens to kids from the infectious disease of toxic stress is as severe as the damage from meningitis or polio or pertussis,' says Dr Tina Hahn, a pediatrician in Michigan. (Source: the Mail online | Health)
Source: the Mail online | Health - July 12, 2017 Category: Consumer Health News Source Type: news

Study finds toxic mercury is accumulating in the Arctic tundra
(University of Massachusetts Lowell) Vast amounts of toxic mercury are accumulating in the Arctic tundra, threatening the health and well-being of people, wildlife and waterways, according to a UMass Lowell scientist investigating the source of the pollution. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 12, 2017 Category: Biology Source Type: news

More Farmers Around The World Water Crops With Toxic Sewage Than Previously Thought
Climate change could make the problem much worse. (Source: Science - The Huffington Post)
Source: Science - The Huffington Post - July 11, 2017 Category: Science Source Type: news

Science SHOCK: Chlorine in swimming pools transforms sunscreen into cancer-causing toxic chemical right on your skin
(Natural News) If you think you’re doing something good by slathering sunscreen on yourself and your kids before hitting the pool, you might want to think again. A new study places sunscreen firmly on the list of products that can do more harm than good as Russian scientists discover the destructive effects of chlorine in... (Source: NaturalNews.com)
Source: NaturalNews.com - July 11, 2017 Category: Consumer Health News Source Type: news

Asbestos Type Has No Effect on Mesothelioma Latency Period
New research from scientists in Germany sheds more light on the unusually long latency period associated with mesothelioma and other asbestos-related diseases. The study, published earlier this year in the European Respiratory Journal, is the first to track the presence of asbestos fibers in lung tissue over time. Mesothelioma has one of the longest latency periods of any cancer. It typically takes anywhere from 20 to 50 years after a person’s initial exposure to asbestos before symptoms arise. Using the German Mesothelioma Register, researchers at Ruhr-University Bochum discovered the volume of asbestos fibers in...
Source: Asbestos and Mesothelioma News - July 11, 2017 Category: Environmental Health Authors: Matt Mauney Tags: amosite amphibole asbestos exposure asbestos fiber burden asbestos fibers in lungs biopersistence of asbestos bronchoalveolar lavage Chrysotile asbestos Chrysotile asbestos fibers European Respiratory Journal German Mesothelioma Regist Source Type: news

Celebrity doctor warns we should wear toxic sunscreen while talking on our cellphone or using our computer
(Natural News) The fear of getting skin cancer drives many people to wear sunscreen every time they leave the house, even if their plans don’t include spending time outdoors. The sunscreen industry has embraced this line of thinking, which is one big reason that Vitamin D deficiencies are soaring in this country. Melanoma is certainly... (Source: NaturalNews.com)
Source: NaturalNews.com - July 11, 2017 Category: Consumer Health News Source Type: news

Insidious leaders: How the last five U.S. Presidents royally screwed up American food and medicine
(Natural News) Welcome to the United States of GMOs and toxic symptom-cover-up medicine. Over the past few decades, leaders in Washington D.C. have kept American consumers in the dark about the truth regarding toxins in our food and medicine, all while denying us some of our most fundamental rights. However, thanks to leading journalists and... (Source: NaturalNews.com)
Source: NaturalNews.com - July 11, 2017 Category: Consumer Health News Source Type: news