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Medical Device Alert: All Accu-Chek Insight insulin pumps- risk of alarm failure
The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a medical device alert ... (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - September 20, 2017 Category: Drugs & Pharmacology Source Type: news

Q & amp;A: How to Control Development Costs for Implantables
When it comes to implantable devices, the material makeup of the technology is not only critical to the success of the device, but it also has a significant impact on the cost. Often times implantables need to be able to survive some of the harshest conditions in the body, where any kind of unexpected breakdown in materials can have critical adverse effects if they aren’t safely designed. This, of course, leaves many device makers with a very short list of potential materials. Len Czuba is president of Czuba Enterprises, a Chicago, IL-based medical device development consultancy that specializes in helping manufactur...
Source: MDDI - September 20, 2017 Category: Medical Devices Authors: Kristopher Sturgis Tags: MD & M Minneapolis Implants Materials Source Type: news

Diabetes risk: Exercise can cause sufferers to have a SEIZURE - but this can prevent it
DIABETES is where the body is unable to produce enough insulin to cope with an increase in blood sugar levels. Scientists have created a patch to help sufferers exercise safely. (Source: Daily Express - Health)
Source: Daily Express - Health - September 19, 2017 Category: Consumer Health News Source Type: news

Minidose Glucagon for Exercise-Induced Hypoglycemia in T1D Minidose Glucagon for Exercise-Induced Hypoglycemia in T1D
Minidose glucagon given just before moderate intensity exercise prevents hypoglycemia--more so than insulin reduction--in patients with type 1 diabetes.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 18, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

A new approach to high insulin levels
(Universit é de Gen è ve) Diabetes is characterised by a deficiency of insulin. The opposite is the case in congenital hyperinsulinism: patients produce the hormone in excessive quantities. This leads to chronic hypoglycaemia. The disorder can lead to serious brain damage and even death in the worst cases. A team at the University of Geneva (UNIGE), Switzerland, supported by the Swiss National Science Foundation has succeeded in describing the effects of a frequent genetic mutation in cases of congenital hyperinsulinism. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 18, 2017 Category: International Medicine & Public Health Source Type: news

Novo Nordisk ’s Tresiba minimises hypoglycaemia rate in diabetes trial
Denmark-based pharmaceutical firm Novo Nordisk has reported positive results from a clinical trial (DEVOTE) of Tresiba (insulin degludec) to treat patients with type 2 diabetes. (Source: Drug Development Technology)
Source: Drug Development Technology - September 17, 2017 Category: Pharmaceuticals Source Type: news

Novo Nordisk Pharmatech Showcases Recombinant Insulin at BioProcess International Conference and Exhibition
Novo Nordisk has announced it will be attending the BioProcess International conference and exhibition. (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - September 17, 2017 Category: Pharmaceuticals Source Type: news

Women who carry excess abdominal fat have a 50% chance of developing lung and bowel cancer
(Natural News) A new study found that women who carry excess abdominal fat have more chances of having lung and bowel cancer, according to the Daily Mail report. Experts said that excess tummy fat triggers an increase in insulin which is known to disrupt hormone production, and excess body fat increases chronic inflammation. Both are... (Source: NaturalNews.com)
Source: NaturalNews.com - September 17, 2017 Category: Consumer Health News Source Type: news

Targeting Hypoglycemia and Glycemic Variability in T2D? More From DEVOTE Targeting Hypoglycemia and Glycemic Variability in T2D? More From DEVOTE
Secondary analyses from the DEVOTE trial comparing the ultralong-acting insulin degludec with insulin glargine examine associations between glycemic variability and severe hypoglycemia and outcomes.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 15, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Diabetes treatment: THIS new drug could be biggest development since discovery of insulin
DIABETES is a condition where blood sugar levels are elevated. Researchers have discovered a drug for type 2 could also help symptoms of type 1. (Source: Daily Express - Health)
Source: Daily Express - Health - September 15, 2017 Category: Consumer Health News Source Type: news

Heath Tip: Dining Out If You Have Diabetes
-- For people who manage diabetes with insulin, eating out can be a source of stress due to the risks of fluctuating blood sugar. The American Diabetes Association suggests how to make eating out safer while you're watching your glucose... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - September 15, 2017 Category: General Medicine Source Type: news

Type 2 Diabetes Drug Improves Glycemic Control in Type 1 Diabetes (FREE)
By Amy Orciari Herman Edited by Andr é Sofair, MD, MPH, and William E. Chavey, MD, MS The type 2 diabetes drug dapagliflozin helps improve glycemic control when added to insulin therapy in patients with type 1 diabetes, according to an … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - September 14, 2017 Category: Primary Care Source Type: news

Another SGLT2 Drug Shines as Insulin Adjunct in T1D (CME/CE)
(MedPage Today) -- Dapagliflozin lowered HbA1c in phase III trial (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - September 14, 2017 Category: Cardiology Source Type: news

DEPICT-1: Dapagliflozin Works in T1D With Little Ketoacidosis DEPICT-1: Dapagliflozin Works in T1D With Little Ketoacidosis
Dapagliflozin provided significant reductions in HbA1c, total daily insulin dose, and body weight in type 1 diabetes and was well tolerated, with no new safety signals, in a 24-week trial.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 14, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Astra's Farxiga results may open up type 1 diabetes opportunity
FRANKFURT (Reuters) - AstraZeneca's Farxiga was shown to help type-1 diabetics when added to standard insulin therapy, possibly opening up a additional market opportunity for the type-2 diabetes drug, the British drugmaker said in a statement on Thursday. (Source: Reuters: Health)
Source: Reuters: Health - September 14, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Insulin therapy initially declined and delayed by an average of 2 years
(Brigham and Women's Hospital) Thirty percent of type 2 diabetic patients don't begin insulin when it's initially recommended, with the average start time being two years later. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 14, 2017 Category: International Medicine & Public Health Source Type: news

Medtronic Issues Voluntary Recall of Certain Insulin Pump Infusion Sets
Medtronic is telling patients that certain lots of its infusion sets for its insulin pumps are being recalled as part of a voluntary effort. The problematic infusion sets, which patients can identify by checking REF and LOT numbers on the available site, have a vent membrane that may be more likely to get blocked, possibly leading to too-high levels of insulin being delivered. This could endanger the patient and potentially cause hypoglycemia. The vulnerable vent membrane was discontinued in April 2017, so infusion sets manufactured since then include an updated component and do not fall under this voluntary recall. Patien...
Source: MDDI - September 14, 2017 Category: Medical Devices Authors: Marie Thibault Tags: Medical Device Business Source Type: news

How Weight Loss Can Reverse Type 2 Diabetes
An analysis published in The BMJ aims to let doctors and the public in on a little-known secret: Type 2 diabetes, in many cases, is curable. People can reverse their diabetes by losing about 33 pounds, say the authors of the new paper, despite popular belief that the diagnosis is always a permanent one. If more people were striving for this goal, and if more doctors were documenting instances of diabetes remission, complication rates and health-care costs could both be reduced dramatically, the authors say. The analysis is based on evidence from recent clinical trials. In one from 2011, people who were recently diagnosed w...
Source: TIME.com: Top Science and Health Stories - September 14, 2017 Category: Consumer Health News Authors: Amanda MacMillan Tags: Uncategorized blood sugar calories can you reverse diabetes diabetic diet Heart Disease how to prevent diabetes insulin is diabetes curable metabolism pre-diabetes type 2 diabetes Weight loss Source Type: news

Artificial pancreas to manage type 1 diabetes gets a trial run
A Yale-led clinical trial is testing an “artificial pancreas,” a hybrid closed-loop system of blood sugar monitoring and insulin delivery. (Source: Yale Science and Health News)
Source: Yale Science and Health News - September 13, 2017 Category: Universities & Medical Training Source Type: news

New oral diabetes drug shows promise for type 1 patients
A Phase 3 clinical trial of the drug, sotagliflozin, show promise at helping to control glucose levels and reduce the need for insulin in type 1 diabetics. (Source: Health News - UPI.com)
Source: Health News - UPI.com - September 13, 2017 Category: Consumer Health News Source Type: news

Type 2 diabetes can be reversed by a low calorie diet
Newcastle University researchers found that losing less than one gram of fat from the pancreas can re-start insulin production, reversing type 2 diabetes. (Source: the Mail online | Health)
Source: the Mail online | Health - September 13, 2017 Category: Consumer Health News Source Type: news

Type 2 diabetes IS reversible
Newcastle University researchers found that losing less than one gram of fat from the pancreas can re-start insulin production, reversing type 2 diabetes. (Source: the Mail online | Health)
Source: the Mail online | Health - September 13, 2017 Category: Consumer Health News Source Type: news

New oral diabetes drug shows promise in phase 3 trial for patients with type 1 diabetes
(University of Colorado Anschutz Medical Campus) A University of Colorado Anschutz Medical Campus study finds sotagliflozin helps control glucose and reduces the need for insulin in patients with type 1 diabetes. Principal results were published today in the New England Journal of Medicine of a global Phase 3 clinical trial in patients with type 1 diabetes treated with sotagliflozin. Sotagliflozin has shown promise in improving glucose control without any increase in severe hypoglycemia or diabetic ketoacidosis compared to insulin alone. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 13, 2017 Category: International Medicine & Public Health Source Type: news

3-D protein structure offers insight into rapid communication by brain cells
(Howard Hughes Medical Institute) New HHMI research reveals how three proteins help brain cells synchronize the release of chemical signals. A similar interaction may play a role in how cells secrete insulin and airway mucus, too. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 13, 2017 Category: International Medicine & Public Health Source Type: news

Glucose monitoring tech to be available on prescription across UK
Finger-prick testing for blood sugar levels could become obsolete, say experts Related items fromOnMedica Glucose self-monitoring may not improve control in non-insulin-treated type 2 diabetes Annual diabetes checks reduce mortality risk for people with diabetes 'Disturbing' type 2 diabetes rise in children NHS must hold CCGs accountable for poor diabetes care Poor diabetes education leading to health complications (Source: OnMedica Latest News)
Source: OnMedica Latest News - September 13, 2017 Category: UK Health Source Type: news

Medtronic Announces Voluntary Recall of Diabetes Infusion Sets
Medtronic plc (NYSE:MDT) announced today that it has started to inform patients worldwide of a voluntary recall of specific lots of infusion sets used with all models of Medtronic insulin pumps. The recall is related to a certain discontinued component in these infusion sets and does not include insulin pumps or glucose sensors. (Source: Food and Drug Administration)
Source: Food and Drug Administration - September 12, 2017 Category: Food Science Source Type: news

CGM Benefits Type 1 Diabetes With Insulin Pumps or Shots CGM Benefits Type 1 Diabetes With Insulin Pumps or Shots
Two-year data show benefit of real-time CGM for patients with type 1 diabetes, regardless of insulin delivery mode.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 12, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Apple-shaped women are more at risk of cancer
Researchers from Nordic Bioscience and ProScion in Denmark found abdominal fat triggers the release of insulin, while excess weight causes chronic inflammation, both of which are linked to cancer. (Source: the Mail online | Health)
Source: the Mail online | Health - September 12, 2017 Category: Consumer Health News Source Type: news

More people treated with once-weekly semaglutide achieved reductions in both glucose and weight vs. comparator treatments
A post-hoc analysis of the SUSTAIN 1-5 trials demonstrated that a greater proportion of adults with type 2 diabetes achieved a clinically meaningful reduction in both HbA1c and body weight with once-weekly semaglutide vs. comparator treatments. Comparators included placebo, sitagliptin, insulin glargine U100 or exenatide extended release (ER). (Source: World Pharma News)
Source: World Pharma News - September 12, 2017 Category: Pharmaceuticals Tags: Featured Novo Nordisk Business and Industry Source Type: news

Researchers identify critical molecular link between inflammation and diabetes
(University of Maryland School of Medicine) A new study has uncovered how inflammation contributes to a key feature of diabetes, the body's inability to metabolize glucose, a condition known as insulin resistance. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 12, 2017 Category: International Medicine & Public Health Source Type: news

Medtronic Recalls Diabetes MiniMed Infusion Sets Worldwide Medtronic Recalls Diabetes MiniMed Infusion Sets Worldwide
The vent membrane in the recalled infusion sets may be susceptible to being blocked by fluid during the process of priming/fill-tubing, which may lead to over-delivery of insulin.News Alerts (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 11, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology News Alert Source Type: news

MassDevice.com +5 | The top 5 medtech stories for September 11, 2017
Say hello to MassDevice +5, a bite-sized view of the top five medtech stories of the day. This feature of MassDevice.com’s coverage highlights our 5 biggest and most influential stories from the day’s news to make sure you’re up to date on the headlines that continue to shape the medical device industry. Get this in your inbox everyday by subscribing to our newsletters.   5. Medical device value: Here’s how you work it into your design Public and private payers are increasingly demanding that health providers manage their patient populations more effectively and efficiently. That means that m...
Source: Mass Device - September 11, 2017 Category: Medical Devices Authors: MassDevice Tags: News Well Plus 5 Source Type: news

Medtronic recalls insulin infusion sets
Medtronic (NYSE:MDT) said today that it’s recalling some of the infusion sets used with its insulin pumps due to problems with a discontinued component. The Fridley, Minn.-based medical device titan said the problem involves a vent membrane that’s susceptible to blockage during priming and fill-tubing. No pumps or glucose sensors are affected by the recall, Medtronic said, and infusion sets made since April 2017 use an updated vent membrane design. Get the full story on our sister site, Drug Delivery Business News. The post Medtronic recalls insulin infusion sets appeared first on MassDevice. (Source: Mass Device)
Source: Mass Device - September 11, 2017 Category: Medical Devices Authors: Brad Perriello Tags: Diabetes Recalls Wall Street Beat Medtronic Source Type: news

Morning Break: Cancer and Alcohol; Insulin Prices; Quick Cancer Diagnosis
(MedPage Today) -- Health news and commentary from around the Web gathered by the MedPage Today staff (Source: MedPage Today Pulmonary)
Source: MedPage Today Pulmonary - September 8, 2017 Category: Respiratory Medicine Source Type: news

Degludec Takes Insulin'To the Next Level'Degludec Takes Insulin'To the Next Level '
Will degludec replace glargine in the real world? Get the community clinician perspective on the DEVOTE trial here.Medscape Diabetes & Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 8, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology Commentary Source Type: news

Biocon's insulin facility in Malaysia clears inspections for European market
The facility, set up with an investment of $275 million, is designed to manufacture recombinant human insulin and insulin analogs for the global market. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - September 7, 2017 Category: Pharmaceuticals Source Type: news

Closed-Loop Insulin Delivery System Aces Skiing Challenge in Diabetes Closed-Loop Insulin Delivery System Aces Skiing Challenge in Diabetes
The University of Virginia's investigational"artificial pancreas" controlled blood glucose levels and minimized hypoglycemia among teenagers with type 1 diabetes during 5 days at ski camp.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 7, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Viral "cleanliness" ties to type-1 diabetes in groundbreaking new research... more viral diversity LOWERS risk
(Natural News) Type 1 diabetes is a chronic autoimmune disease in which a patient’s own immune system attacks and destroys the cells needed to produce insulin to control blood-sugar levels. Doctors often diagnose this type of diabetes in childhood or early adulthood. Though the exact cause of Type 1 diabetes is unknown, new research has... (Source: NaturalNews.com)
Source: NaturalNews.com - September 6, 2017 Category: Consumer Health News Source Type: news

Substance in coffee delays onset of diabetes in laboratory mice
(American Chemical Society) In recent years, researchers have identified substances in coffee that could help quash the risk of developing type 2 diabetes. But few of these have been tested in animals. Now in study appearing in ACS' Journal of Natural Products, scientists report that one of these previously untested compounds appears to improve cell function and insulin sensitivity in laboratory mice. The finding could spur the development of new drugs to treat or even prevent the disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 6, 2017 Category: International Medicine & Public Health Source Type: news

Cognitive Test Predicts Elderly Insulin Injection Success
Number of animal names recalled in one minute was the most useful indicator (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - September 5, 2017 Category: Psychiatry Tags: Endocrinology, Family Medicine, Geriatrics, Internal Medicine, Nursing, Pharmacy, Psychiatry, Journal, Source Type: news

Women with PCOS are 4 times more likely to get diabetes
Sufferers of PCOS can develop insulin resistance. A Danish study found women with the common ovary condition are diagnosed with diabetes 4 years earlier than other patients. (Source: the Mail online | Health)
Source: the Mail online | Health - September 1, 2017 Category: Consumer Health News Source Type: news

Sanofi wins tentative FDA nod for Admelog insulin lispro injection
Sanofi (NYSE:SNY) said today that the FDA granted the company tentative approval for its Admelog insulin lispro injection. The decision is based on physicochemical, non-clinical and clinical similarity to another, already-approved insulin lispro injection. The compound is contraindicated during hypoglycemia episodes and in patients with hypersensitivity to insulin lispro or one of its other ingredients, Sanofi said. Get the full story at our sister site, Drug Delivery Business News. The post Sanofi wins tentative FDA nod for Admelog insulin lispro injection appeared first on MassDevice. (Source: Mass Device)
Source: Mass Device - September 1, 2017 Category: Medical Devices Authors: Sarah Faulkner Tags: Diabetes Drug-Device Combinations Food & Drug Administration (FDA) Pharmaceuticals Regulatory/Compliance Wall Street Beat Sanofi-Aventis Source Type: news

Diabetes orgs send insulin, glucose meters to Texas
Thousands of people in Texas have been displaced from their homes after Hurricane Harvey landed there last week, leaving many without life-saving medication and supplies. People with diabetes are especially vulnerable, since many require daily insulin injections and regular monitoring of their blood glucose levels. In what they have described as a ‘landmark partnership’, the American Diabetes Association, JDRF and Insulin of Life have gathered and shipped more than 3,750 pounds of donated supplies to people with diabetes impacted by the catastrophic hurricane. Get the full story at our sister site, Drug Deliver...
Source: Mass Device - September 1, 2017 Category: Medical Devices Authors: Sarah Faulkner Tags: Diabetes Pharmaceuticals American Diabetes Assn. Juvenile Diabetes Research Foundation (JDRF) Source Type: news

Heart hormones protect against obesity and insulin resistance
Enhanced natriuretic peptide signalling in adipose tissue protects against obesity and insulin resistance, according to a study published inScience Signalling.Medical Xpress (Source: Society for Endocrinology)
Source: Society for Endocrinology - September 1, 2017 Category: Endocrinology Source Type: news

Sanofi Receives Tentative FDA Approval of Admelog (insulin lispro injection) 100 units/mL
BRIDGEWATER, N.J., Sept. 1, 2017 /PRNewswire-USNewswire/ -- Sanofi announced today that the U.S. Food and Drug Administration (FDA) granted tentative approval for Admelog ® (insulin lispro injection) 100 Units/mL, a rapid-acting human insulin... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - September 1, 2017 Category: Drugs & Pharmacology Source Type: news

Sitting for 20 minutes less a day won't make you 'more muscly'
Conclusion Despite the encouraging headlines, the study showed it isn't easy to get people to reduce their overall sedentary time. It's interesting that people were better able to make changes at home – especially when both parents had been through the programme – than in the office. Future programmes could look at whether workplace interventions, which might include group activities or changes to the office environment, are more successful at reducing time spent sitting. We don't know the clinical significance of the small changes in some of the physical and biochemical results found in the programme group. ...
Source: NHS News Feed - August 31, 2017 Category: Consumer Health News Tags: Lifestyle/exercise Source Type: news

Revolutionary Glucose Monitoring Technology FreeStyle ® Libre Now Reimbursed Across Japan
- NATIONALLY REIMBURSED FOR ALL PEOPLE WITH DIABETES ON INSULIN THERAPY - MORE THAN 1 MILLION PEOPLE, BOTH TYPE 1 AND TYPE 2 (Source: Abbott.com)
Source: Abbott.com - August 31, 2017 Category: Pharmaceuticals Source Type: news

How Displaced Texans Who Need Critical Medicine And Care Can Get Help
Despite Harvey, things like insulin shots, antiretrovirals and dialysis can't be interrupted. (Source: Healthy Living - The Huffington Post)
Source: Healthy Living - The Huffington Post - August 31, 2017 Category: Consumer Health News Source Type: news

Glia relay differentiation cues to coordinate neuronal development in Drosophila
Neuronal birth and specification must be coordinated across the developing brain to generate the neurons that constitute neural circuits. We used the Drosophila visual system to investigate how development is coordinated to establish retinotopy, a feature of all visual systems. Photoreceptors achieve retinotopy by inducing their target field in the optic lobe, the lamina neurons, with a secreted differentiation cue, epidermal growth factor (EGF). We find that communication between photoreceptors and lamina cells requires a signaling relay through glia. In response to photoreceptor-EGF, glia produce insulin-like peptides, w...
Source: ScienceNOW - August 31, 2017 Category: Science Authors: Fernandes, V. M., Chen, Z., Rossi, A. M., Zipfel, J., Desplan, C. Tags: Development r-articles Source Type: news

Nurse Guilty of Killing Eight in Canadian Nursing Homes Nurse Guilty of Killing Eight in Canadian Nursing Homes
Pleading guilty, she tells a judge she injected them with insulin for no medical reason. She also pleads guilty to four counts of attempted murder and two counts of aggravated assault.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 30, 2017 Category: Consumer Health News Tags: Nursing News Source Type: news