Largest ever evaluation of the cardiovascular risk of rosiglitazone published
Analysis of raw individual patient level data gives more accurate picture of drug ’s link to heart problems Related items fromOnMedica People on statins at greater risk of skin infections and diabetes Adding insulin to metformin linked to higher mortality Vitamin D does not reduce kidney damage in type 2 diabetes Raised risk of MI and mortality when starting sulfonylurea Use of DPP-4 inhibitors associated with increased risk of IBD (Source: OnMedica Latest News)
Source: OnMedica Latest News - February 5, 2020 Category: UK Health Source Type: news

Negotiated Prices, Formulary Could Cut Medicare Rx Spending
WEDNESDAY, Feb. 5, 2020 -- Using negotiated prices and a defined formulary, similar to the Department of Veterans Affairs (VA), Medicare could save billions of dollars on prescription insulin for patients with diabetes, according to a research... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 5, 2020 Category: Pharmaceuticals Source Type: news

Negotiating Insulin Costs Could Save U.S. Billions
The researchers said that if Medicare were allowed to negotiate drug prices like the U.S. Department of Veterans Affairs (VA) can, Medicare could save about $4.4 billion just on insulin. (Source: WebMD Health)
Source: WebMD Health - February 4, 2020 Category: Consumer Health News Source Type: news

Medicare Could Save Billions If Allowed to Negotiate Insulin Prices
TUESDAY, Feb. 4, 2020 -- If you don't need insulin, you probably haven't paid much attention to its skyrocketing cost, but new research shows that exorbitant drug pricing eventually affects everyone. The study found that in 2017, Medicare spent... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 4, 2020 Category: General Medicine Source Type: news

Medicare Could Save Billions If Allowed to Negotiate Insulin Prices
Title: Medicare Could Save Billions If Allowed to Negotiate Insulin PricesCategory: Health NewsCreated: 2/4/2020 12:00:00 AMLast Editorial Review: 2/4/2020 12:00:00 AM (Source: MedicineNet Diabetes General)
Source: MedicineNet Diabetes General - February 4, 2020 Category: Endocrinology Source Type: news

Researchers successfully test coin-sized smart insulin patch, potential diabetes treatment
(University of North Carolina Health Care) The study, published in Nature Biomedical Engineering, describes research conducted on mice and pigs. The research team, led by Zhen Gu, Ph.D., professor of bioengineering at the UCLA Samueli School of Engineering, is applying for FDA approval of clinical trials in humans. Gu and colleagues conducted the initial successful tests of the smart insulin patch in mice in 2015 as part of the UNC/NC State Joint Department of Biomedical Engineering. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 4, 2020 Category: International Medicine & Public Health Source Type: news

Type 1 diabetes could be tackled by injecting insulin-producing cells into the eye 
In a new trial, patients will have donor cells injected into the anterior chamber - the fluid-filled space between the iris (the coloured part of the eye) and the inner surface of the cornea at the front. (Source: the Mail online | Health)
Source: the Mail online | Health - February 4, 2020 Category: Consumer Health News Source Type: news

First Approval for Fast-Acting Lispro for Diabetes; EU OKs Oral Semaglutide First Approval for Fast-Acting Lispro for Diabetes; EU OKs Oral Semaglutide
EMA panel recommends approval of oral GLP-1 agonist semaglutide for type 2 diabetes. It has also given the thumbs up to a mealtime, or fast-acting form, of insulin lispro for adults with diabetes.International Approvals (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - January 31, 2020 Category: Drugs & Pharmacology Tags: Diabetes & Endocrinology News Alert Source Type: news

Study: Tasting no-calorie sweetener may affect insulin response on glucose tolerance test
(University of Illinois at Urbana-Champaign, News Bureau) New research led by University of Illinois professor of food science and human nutrition M. Yanina Pepino, left, suggests that just tasting something sweet, such as the artificial sweetener sucralose, may affect individuals' responses on glucose tolerance tests. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 31, 2020 Category: International Medicine & Public Health Source Type: news

Human Insulin Is Available For As Little As $24.88 - But It ’s Not For Everyone
Human insulin is different from synthetic insulin, and one is significantly cheaper. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - January 30, 2020 Category: Pharmaceuticals Authors: John LaMattina, Contributor Source Type: news

Type 2 diabetes: The dangerous symptom that affects this body part
TYPE 2 diabetes is a condition that causes the level of sugar i the blood to become too high, caused by problems with the body's level of insulin. Spotting the early warning signs of the condition is crucial and there is a dangerous symptom found in this body part. What is it? (Source: Daily Express - Health)
Source: Daily Express - Health - January 30, 2020 Category: Consumer Health News Source Type: news

CVS offers option for diabetes drugs with no out-of-pocket cost
CVS Health Corp said on Wednesday it is launching a prescription drug coverage plan in which patients would have no out-of-pocket costs for insulin and other expensive diabetes treatments. (Source: Reuters: Health)
Source: Reuters: Health - January 29, 2020 Category: Consumer Health News Tags: healthNews Source Type: news

I Just Bought A Vial Of Human Insulin For $24.88
Human insulin is different from synthetic insulin, and one is significantly cheaper. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - January 29, 2020 Category: Pharmaceuticals Authors: John LaMattina, Contributor Source Type: news

Lilly plans donation of 200,000 insulin KwikPens over next three years to support lower-income communities
Insulin donation, along with $2 million in grants to relief agencies, extends program launched in 2018 INDIANAPOLIS, Jan. 28, 2020 -- (Healthcare Sales & Marketing Network) -- Starting this month, Eli Lilly and Company (NYSE: LLY) will donate at least ... Biopharmaceuticals, Drug Delivery, Endocrinology Eli Lilly, KwikPen, insulin, Humalog, diabetes (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - January 28, 2020 Category: Pharmaceuticals Source Type: news

Illinois Law Caps Insulin Patient Costs at $100 Monthly Illinois Law Caps Insulin Patient Costs at $100 Monthly
On Friday, the governor of Illinois signed a law capping monthly insulin costs at $100 for people covered by state-regulated commercial health insurance plans.Associated Press (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 27, 2020 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Type 2 diabetes: Having this problem with your feet could mean you’re at risk
TYPE 2 diabetes is a serious problem and a worldwide health epidemic. The condition is where the insulin the pancreas makes can't work properly and noticing this symptom in your feet could be a warning that you may be at risk. What is it? (Source: Daily Express - Health)
Source: Daily Express - Health - January 27, 2020 Category: Consumer Health News Source Type: news

High Insulin Prices May Be First Remedy For New Blue Cross Drug Maker
The new subsidiary of nonprofit generic drug maker Civica Rx and backed by Blue Cross and Blue Shield plans is poised to go after prescriptions that are generic yet have little competition and high prices like insulin. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - January 24, 2020 Category: Pharmaceuticals Authors: Bruce Japsen, Contributor Source Type: news

Insulin Resistance (Symptoms, Causes, Diagnosis, Treatment, and Reversal))
Title: Insulin Resistance (Symptoms, Causes, Diagnosis, Treatment, and Reversal))Category: Diseases and ConditionsCreated: 2/10/2004 12:00:00 AMLast Editorial Review: 1/24/2020 12:00:00 AM (Source: MedicineNet Diabetes General)
Source: MedicineNet Diabetes General - January 24, 2020 Category: Endocrinology Source Type: news

What Will It Take to Lower the Cost of Insulin in the US? What Will It Take to Lower the Cost of Insulin in the US?
Mayo Clinic hematologist S. Vincent Rajkumar breaks down the complexity of the problem and outlines potential solutions.Medscape Medical News (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - January 22, 2020 Category: Drugs & Pharmacology Tags: Diabetes & Endocrinology News Source Type: news

Vitamin D supplementation linked to potential improvements in blood pressure in children
(University of Pittsburgh) Overweight and obese vitamin D-deficient children who took a relatively high dose of vitamin D every day for six months had lower blood pressure and improved insulin sensitivity than their peers who took a lower dose. The study did not show improvements in other markers of cardiovascular and metabolic health, a finding that indicates vitamin D supplementation alone may not be the cure-all for children at highest risk for diabetes and heart disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 21, 2020 Category: International Medicine & Public Health Source Type: news

Medtech in a Minute: Bigfoot Has Friends in High Places, DexCom Shines at JPM, and More
Bigfoot Gets by with a Little Help from Its Friends Bigfoot Biomedical is on track to submit its diabetes technology for FDA clearance this year, and the product could hit the market by year end. It helps that the company has some friends with deep pockets like Abbott and other investors that kicked in a total of $45 million in an initial tranche of a series C financing. Bigfoot's injection-based digitized insulin dosing platform uses a connected insulin pen-based system that integrates Abbott’s FreeStyle Libre glucose sensing technology.   DexCom Gives JPM ...
Source: MDDI - January 18, 2020 Category: Medical Devices Authors: Amanda Pedersen Tags: Business Source Type: news

Switching to Degludec Reduces Hypoglycemia Rates Switching to Degludec Reduces Hypoglycemia Rates
Insulin-treated diabetes patients who switched to degludec realized lower rates of hypoglycemia and improved glycemic control.Journal of Clinical Endocrinology & Metabolism (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 17, 2020 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Type 2 diabetes symptoms: Does your breath smell like this? Warning sign of condition
TYPE 2 DIABETES occurs when the body is unable to make functional – or enough of – insulin, resulting in high blood sugar levels and symptoms too easy to ignore. This condition isn’t to be overlooked, though, as it can lead to deadly consequences. (Source: Daily Express - Health)
Source: Daily Express - Health - January 15, 2020 Category: Consumer Health News Source Type: news

Eli Lilly to offer half-priced versions of two more insulin products
Eli Lilly and Co said on Tuesday it plans to sell two versions of insulin products at half their current U.S. list prices, eight months after it started selling a half-priced version of its widely-used Humalog injection. (Source: Reuters: Health)
Source: Reuters: Health - January 14, 2020 Category: Consumer Health News Tags: healthNews Source Type: news

Uganda: Diabetes Diet - Control Your Portions
[Monitor] There are two types of Diabetes. Diabetes 1 is when one's pancreas cannot produce insulin while Diabetes 2 is where the body fails to use sugar properly. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - January 14, 2020 Category: African Health Source Type: news

Abbott Kicks in for Bigfoot & #039;s $45M Financing
It may only be January, but it looks like 2020 could be Bigfoot Biomedical's year. The company is on track to submit its Bigfoot Unity diabetes technology for FDA clearance this year, and the product could hit the market by the year end. To help the company reach that target, Abbott and other investors kicked in a total of $45 million in an initial tranche of a series C financing. Bigfoot's technology is an injection-based digitized insulin dosing platform which uses a connected insulin pen-based system that integrates Abbott’s FreeStyle Libre glucose sensing technology. Series C funds will al...
Source: MDDI - January 13, 2020 Category: Medical Devices Authors: Amanda Pedersen Tags: Business Source Type: news

New cellular player involved in obesity discover
(Instituto Gulbenkian de Ciencia) The group also found that in experimental disease models that mimic the development of human obesity, loss of iRhom2 results in less fat accumulation in the body. In addition, adipose tissues are protected from inflammation and from the development of insulin resistance, two known hallmarks of metabolic disease. The discovery, besides improving the understanding of the cellular mechanisms associated with obesity, could be potentially useful in the future for the development of new drugs to treat the disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 10, 2020 Category: International Medicine & Public Health Source Type: news

New insulin compound could improve therapy for diabetes patients
(Florey Neuroscience Institutes) Researchers have successfully created a non-fibrillating form of human insulin in a discovery that could improve the clinical delivery and cost of insulin for people living with diabetes. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 9, 2020 Category: International Medicine & Public Health Source Type: news

Take heart: Pitt study reveals how relaxin targets cardiovascular disease
(University of Pittsburgh) As a healthy heart ages, it becomes more susceptible to cardiovascular diseases. Though researchers have discovered that relaxin, an insulin-like hormone, suppresses atrial fibrillation (AF), inflammation, and fibrosis in aged rats, the underlying mechanisms of these benefits are still unknown. In a recent Scientific Reports paper, University of Pittsburgh researchers discuss how relaxin interacts with the body's signaling processes to produce a fundamental mechanism that may have great therapeutic potential. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 7, 2020 Category: International Medicine & Public Health Source Type: news

FDA OKs Faster Aspart Insulin for Children With Diabetes FDA OKs Faster Aspart Insulin for Children With Diabetes
The formulation was initially approved in 2017 and was approved for insulin pump use in 2019.FDA Approvals (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - January 7, 2020 Category: Drugs & Pharmacology Tags: Diabetes & Endocrinology News Alert Source Type: news

Can insulin production be restored? Study finds potential new treatments for Type 1 and Type 2 diabetes
(Natural News) A recent study brought up the possibility of restoring the function of insulin-producing beta cells in diabetes patients. It showed how pancreatic cells change their behavior during the onset of the disease. The study, which employed a human cell system, revealed that diabetes altered the RNA messaging system that gave orders to proteins to... (Source: NaturalNews.com)
Source: NaturalNews.com - January 6, 2020 Category: Consumer Health News Source Type: news

FDA Approves Fiasp (insulin aspart injection) for the Treatment of Children with Diabetes
PLAINSBORO, N.J., Jan. 6, 2020 /PRNewswire/ -- Novo Nordisk today announced that the U.S. Food and Drug Administration (FDA) has approved Fiasp (insulin aspart injection) 100 u/mL for use as a new mealtime insulin option for children with diabetes.1... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - January 6, 2020 Category: Drugs & Pharmacology Source Type: news

Driving safety and real-time glucose monitoring in insulin-dependent diabetes - Merickel J, High R, Smith L, Wichman C, Frankel E, Smits K, Drincic A, Desouza C, Gunaratne P, Ebe K, Rizzo M.
Our goal is to address the need for driver-state detection using wearable and in-vehicle sensor measurements of driver physiology and health. To address this goal, we deployed in-vehicle systems, wearable sensors, and procedures capable of quantifying real... (Source: SafetyLit)
Source: SafetyLit - January 6, 2020 Category: International Medicine & Public Health Tags: Distraction, Fatigue, Chronobiology, Vigilance, Workload Source Type: news

Type 2 diabetes: Do you get less than this amount of sleep a night? Major risk factor
TYPE 2 diabetes is a chronic condition in which the pancreas doesn ’t produce enough insulin to control blood sugar levels - a mechanism that can lead to life-threatening complications. Type 2 diabetes risk is strongly tied to unhealthy lifestyle decisions and failing to get enough of a certain activity can raise your risk of developing the serious condition. (Source: Daily Express - Health)
Source: Daily Express - Health - January 6, 2020 Category: Consumer Health News Source Type: news

Novo Nordisk to Offer Free Insulin to U.S. Patients in Immediate Need Novo Nordisk to Offer Free Insulin to U.S. Patients in Immediate Need
Novo Nordisk said on Thursday it would offer free, one-time supply of insulin to people in immediate need and at risk of rationing the medication, the rising price of which has attracted fierce criticism from lawmakers and regulators.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 3, 2020 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Coffee Consumption Does Not Affect Insulin Sensitivity
FRIDAY, Jan. 3, 2020 -- Consumption of four cups of coffee daily does not impact insulin sensitivity, according to a study published online Dec. 31 in the American Journal of Clinical Nutrition. Derrick Johnston Alperet, from the National University... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 3, 2020 Category: Pharmaceuticals Source Type: news

Novo Nordisk to offer free insulin to U.S. patients in immediate need
Novo Nordisk said on Thursday it would offer free, one-time supply of insulin to people in immediate need and at risk of rationing the medication, the rising price of which has attracted fierce criticism from lawmakers and regulators. (Source: Reuters: Health)
Source: Reuters: Health - January 2, 2020 Category: Consumer Health News Tags: healthNews Source Type: news

New trigger for type 2 diabetes discovered
According to a study published inDiabetes, high levels of fatty acids may cause beta cells to increase production of insulin and trigger type 2 diabetes.New Atlas (Source: Society for Endocrinology)
Source: Society for Endocrinology - January 2, 2020 Category: Endocrinology Source Type: news

Type 2 diabetes: Do you feel like this? It could be a warning sign of the condition
TYPE 2 diabetes is a condition in which cells cannot use blood sugar efficiently for energy. This occurs when blood sugar levels get too high over time, and the cells become insensitive or resistant to insulin. (Source: Daily Express - Health)
Source: Daily Express - Health - January 2, 2020 Category: Consumer Health News Source Type: news

Nigeria: How I Fought Diabetes in Just 15 Months (III)
[Daily Trust] Saudi Arabia -In just 15 months, I was able to successfully wean myself off any diabetic medication or insulin injection. Even doctors are surprised about my relying on dietary modifications and weight loss alone to abstain from taking any diabetic medication. In fact, most of them would be hesitant to tell you to go without taking any medication and rely on dietary modifications and weight loss alone. When I asked my doctor at the beginning of the treatment if I would ever live without taking any diabetic medication ag (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - January 2, 2020 Category: African Health Source Type: news

High cost of insulin has life-or-death implications for diabetic patients
ROCHESTER, Minn. -- The most commonly used forms of insulin cost 10 times more in the U.S. than in any other developed country, according to a commentary in Mayo Clinic Proceedings. This prohibitive cost is causing some U.S. patients with Type 1 diabetes to ration the amount of insulin they use, with life-threatening implications. The [...] (Source: Mayo Clinic Minnesota News)
Source: Mayo Clinic Minnesota News - January 1, 2020 Category: Hospital Management Source Type: news

Obesity prevention: Dawn-to-sunset fasting can be used for weight management, say scientists
(Natural News) Fasting activates natural processes in the body that improve and support a person’s overall health. A recent study demonstrated that fasting from dawn to sunset for 30 days can increase levels of metabolism-related proteins that help control weight. A group of proteins called tropomyosins regulates the body’s sensitivity to insulin. Higher levels of these proteins... (Source: NaturalNews.com)
Source: NaturalNews.com - December 31, 2019 Category: Consumer Health News Source Type: news

Medtech in a Minute: FTC Blocks a Big Deal, Boston Scientific Scores a Win for Patient Safety, and More
FTC Blocks Illumina-PacBio Deal The Federal Trade Commission is challenging the $1.2 billion-merger between Illumina and PacificBio (PacBio). The agency says Illumina is seeking to unlawfully maintain its monopoly in the U.S. market for next-generation DNA sequencing systems by extinguishing PacBio as a nascent competitive threat.   Fully Disposable Duodenoscope Is a Win for Patient Safety Boston Scientific snagged FDA clearance to sell its Exalt-D single-use duodenoscope in the United States to provide visualization and access to the upper gastrointestinal (GI) t...
Source: MDDI - December 21, 2019 Category: Medical Devices Authors: Amanda Pedersen Tags: Business Source Type: news

ENGAGE AF-TIMI: Insulin Linked to Greater Risk for Stroke, CV Death, Bleeding ENGAGE AF-TIMI: Insulin Linked to Greater Risk for Stroke, CV Death, Bleeding
In a subanalysis, patients with diabetes treated with insulin were at higher risk for these outcomes compared with those not treated with insulin.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - December 20, 2019 Category: Cardiology Tags: Diabetes & Endocrinology News Source Type: news

FDA Authorizes Marketing of Automated Insulin Dosing Controller
Title: FDA Authorizes Marketing of Automated Insulin Dosing ControllerCategory: Health NewsCreated: 12/19/2019 12:00:00 AMLast Editorial Review: 12/20/2019 12:00:00 AM (Source: MedicineNet Diabetes General)
Source: MedicineNet Diabetes General - December 20, 2019 Category: Endocrinology Source Type: news

Researchers discover process that may explain how Type 2 diabetes develops
A new study helps to explain the mechanism by which pancreatic cells secrete high levels of insulin during the early stages of diabetes.A central question in diabetes research is why cells of the pancreas, known as beta cells, initially over-secrete insulin. The prevailing theory was that the body may be in the process of becoming “deaf” to insulin, so beta cells secrete more to compensate. But isolated beta cells still over-secrete insulin, which exposes a gap in that theory.In the new study, researchers set out to understand what other mechanism beyond insulin resistance (that is, the body becoming “dea...
Source: UCLA Newsroom: Health Sciences - December 20, 2019 Category: Universities & Medical Training Source Type: news

FDA Authorizes Marketing of Automated Insulin Dosing Controller
THURSDAY, Dec. 19, 2019 -- The U.S. Food and Drug Administration recently approved marketing of an interoperable automated glycemic controller device, the Tandem Diabetes Care Control-IQ Technology, the agency announced last week. The device... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - December 19, 2019 Category: General Medicine Source Type: news

Regular Moderate Exercise Ups GLP-1 Response in Overweight Men Regular Moderate Exercise Ups GLP-1 Response in Overweight Men
A half hour of daily moderate-intensity exercise was linked with a better response from a hormone that stimulates insulin; more research is needed to explain why this response was only seen in men.Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - December 19, 2019 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news

Trump Administration Takes First Step to Allow Drug Imports From Canada
The proposal is still a long way from being finalized, and many expensive drugs, like insulin, would be excluded from state plans. (Source: NYT)
Source: NYT - December 18, 2019 Category: American Health Authors: Katie Thomas Tags: Drugs (Pharmaceuticals) Prices (Fares, Fees and Rates) United States Politics and Government Trump, Donald J Canada Azar, Alex M II your-feed-healthcare Source Type: news

Tandem ’s New Clearance Strengthens Relationship with DexCom
Tandem Diabetes has won a major nod from FDA that has the potential to advance its partnership with DexCom. The San Diego, CA-based company received clearance for the t:slim X2 insulin pump with Control-IQ technology, which integrates with Dexcom G6 continuous glucose monitoring (CGM) sensor. The technology uses the DexCom G6 CGM sensor values to forecast glucose levels and adjust insulin delivery to ensure the prevention of erratic highs and lows. San Diego, CA-based DexCom’s CGM requires no fingersticks for calibration or diabetes treatment decisions. Tandem first won FDA approval for the t:slim X2 insu...
Source: MDDI - December 17, 2019 Category: Medical Devices Authors: Omar Ford Tags: Digital Health Source Type: news