Advances in neuropathologic research of hypoglycemic brain damage caused by insulin overdose - Tong F, Yang Y, Liang Y, Lopsong TZ, Liu YL, Zhao SQ, He GL, Zhou YW.
The number of death from insulin overdose, including accidental poisoning, suicide and homicide, is increasing these years. The forensic diagnosis of death from insulin overdose is a tough task. Glucose is the main energy source of the brain. Therefore, hy... (Source: SafetyLit)
Source: SafetyLit - April 9, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Eli Lilly Lowers Insulin Costs as Coronavirus Crisis Deepens Eli Lilly Lowers Insulin Costs as Coronavirus Crisis Deepens
Drugmaker Eli Lilly& Co said on Tuesday it has capped the out-of-pocket cost for insulin to $35 per month to help diabetes patients across the United States, many of whom are facing financial difficulties due to the coronavirus outbreak.Reuters Health Information (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - April 9, 2020 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news

How Continuous Glucose Monitoring Systems Are Joining the COVID-19 Fight
In response to healthcare workers asking for safer ways to monitor hospitalized diabetes patients with COVID-19, FDA is allowing both Dexcom and Abbott to supply continuous glucose monitoring (CGM) systems for use in the hospital setting during the pandemic. This allows frontline healthcare workers in hospitals to remotely monitor patients with diabetes in order to minimize exposure to the virus that causes COVID-19 and preserve use of personal protective equipment (PPE). Abbott said it has partnered with the American Diabetes Association, Insulin for Life USA, and the Diabetes Disaster Response Coa...
Source: MDDI - April 8, 2020 Category: Medical Devices Authors: Amanda Pedersen Tags: COVID-19 Source Type: news

Patch Pump Device Could Offer Cheaper Insulin Delivery
Title: Patch Pump Device Could Offer Cheaper Insulin DeliveryCategory: Health NewsCreated: 4/1/2020 12:00:00 AMLast Editorial Review: 4/2/2020 12:00:00 AM (Source: MedicineNet Diabetes General)
Source: MedicineNet Diabetes General - April 2, 2020 Category: Endocrinology Source Type: news

Type 2 diabetes: Six dinner ideas to help lower blood sugar levels
TYPE 2 diabetes occurs when a person isn't able to produce enough insulin to function correctly. If one is living with the condition, certain changes in lifestyle need to take place, often causing worry and confusion. What are five of the best dinner choices for type 2 diabetes? (Source: Daily Express - Health)
Source: Daily Express - Health - April 1, 2020 Category: Consumer Health News Source Type: news

ENDO: Glycemic Control Good for Regular Human Insulin With V-Go
WEDNESDAY, April 1, 2020 -- For patients with type 2 diabetes (T2D), glycemic control is similar with use of regular human insulin (RHI) and rapid-acting insulin (RAI) when delivered with a wearable insulin delivery device, V-Go, according to a... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 1, 2020 Category: Pharmaceuticals Source Type: news

Patch Pump Device Could Offer Cheaper Insulin Delivery
WEDNESDAY, April 1, 2020 -- Rising prices have grabbed headlines as people struggle to afford their lifesaving insulin, but new research may have found an alternative for people with type 2 diabetes. The study found that combining a wearable,... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - April 1, 2020 Category: General Medicine Source Type: news

Biocon says probe on Malaysia manufacturing unit ends
“This is to inform you that Biocon Sdn Bhd, a subsidiary of Biocon, has received the EIR from the USFDA for the pre-approval inspection of its insulins manufacturing facility in Malaysia, for Insulin Glargine. The inspection was conducted between Feb 10 and 21, 2020,” said the company spokespers on in a statement. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - April 1, 2020 Category: Pharmaceuticals Source Type: news

Type 2 diabetes: Curry spice to add to foods to lower blood sugar
TYPE 2 diabetes is an extremely common and serious problem faced by many worldwide. The condition affects insulin in the body, and this affects the pancreas. Thankfully, adding this delicious spice to your meals could greatly help to lower blood sugar and keep you healthy. (Source: Daily Express - Health)
Source: Daily Express - Health - March 31, 2020 Category: Consumer Health News Source Type: news

ENDO: Real-World Data Analyzed for Use of Insulin Pump in T1DM
TUESDAY, March 31, 2020 -- Real-world data support the benefit of using the Medtronic MiniMed 670G insulin pump system for glycemic control in type 1 diabetes, according to a study presented at the virtual meeting of The Endocrine Society, held from... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 31, 2020 Category: Pharmaceuticals Source Type: news

Doctors Describe First Drone Delivery of Diabetes Meds to Patient
MONDAY, March 30, 2020 -- Imagine needing insulin to live but a natural disaster suddenly cuts off access to your medication. New drone technology may one day come to the rescue by making urgent deliveries to remote locations, researchers say. The... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - March 30, 2020 Category: General Medicine Source Type: news

New therapeutic strategy against diabetes
(Universitat Autonoma de Barcelona) A study by the CIBERDEM and the UAB demonstrates that high vitamin D receptor levels in pancreaticβ cells improve resistance to diabetes. The research suggests that the maintenance of the vitamin D receptor expression could be a new therapeutic strategy to counteract insulin-producing pancreatic cell damage and protect against the development of diabetes. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 26, 2020 Category: International Medicine & Public Health Source Type: news

FDA: Insulin Among Drugs Transitioned to Biological Products
TUESDAY, March 24, 2020 -- Insulin and other biologic drugs, such as human growth hormone, have now transitioned to being regulated as biological products, providing a new pathway for approval of biosimilars and interchangeable versions of these... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 24, 2020 Category: Pharmaceuticals Source Type: news

FDA Move Opens Door to Biosimilar Insulins, Other Biologics FDA Move Opens Door to Biosimilar Insulins, Other Biologics
In a historic shift, FDA transitions regulatory pathway for insulin and other biologics, meaning products deemed'biosimilar'will be able to compete more easily with brands, in theory lowering prices.Medscape Medical News (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - March 24, 2020 Category: Drugs & Pharmacology Tags: Diabetes & Endocrinology News Source Type: news

Updates from Lilly about Insulin Supply and Affordability
INDIANAPOLIS, March 24, 2020 -- (Healthcare Sales & Marketing Network) -- To keep the diabetes community informed about important developments from the COVID-19 crisis, Eli Lilly and Company (NYSE: LLY) today is providing updates related to insulin supply... Biopharmaceuticals, Endocrinology Eli Lilly, diabetes, insulin (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - March 24, 2020 Category: Pharmaceuticals Source Type: news

Janssen Highlights Continued Commitment to Cardiovascular & Metabolic Healthcare Solutions with Late-Breaking Data at the First Fully Virtual American College of Cardiology Scientific Session
RARITAN, N.J., March 20, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that it will unveil late-breaking data from its leading cardiovascular and metabolism portfolio during the virtual American College of Cardiology’s 69th Annual Scientific Session together with the World Congress of Cardiology (ACC.20/WCC) on March 28-30, 2020. Notably, four late-breaking abstracts for XARELTO® (rivaroxaban) will be presented, including data from the Phase 3 VOYAGER PAD study in patients with symptomatic peripheral artery disease (PAD) after lower-extremity revascularization.Click to...
Source: Johnson and Johnson - March 20, 2020 Category: Pharmaceuticals Source Type: news

High insulin levels linked to increased asthma risk in children
High insulin levels during childhood may increase risk of asthma, according to research to be presented at the American Academy of Allergy Asthma and Immunology Annual Meeting.Endocrinology Advisor (Source: Society for Endocrinology)
Source: Society for Endocrinology - March 20, 2020 Category: Endocrinology Source Type: news

A decoy insulin receptor in worms?
(Source: ScienceNOW)
Source: ScienceNOW - March 19, 2020 Category: Science Authors: Ray, L. B. Tags: twil Source Type: news

Causal Link Suggested for IGF-1 Concentrations, Breast Cancer
TUESDAY, March 17, 2020 -- There seems to be a causal association between circulating insulin-like growth factor-1 (IGF-1) concentrations and breast cancer, according to a study published online March 10 in the Annals of Oncology. Neil Murphy,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 17, 2020 Category: Pharmaceuticals Source Type: news

Insulin Costs May Be Capped in a Medicare Program
If drug companies and insurers agree to participate, the Trump administration proposes limiting insulin costs to $35 a month for some older Americans. (Source: NYT Health)
Source: NYT Health - March 11, 2020 Category: Consumer Health News Authors: Katie Thomas Tags: Drugs (Pharmaceuticals) Diabetes Health Insurance and Managed Care Insulin Elderly Prices (Fares, Fees and Rates) Medicare Centers for Medicare and Medicaid Services Verma, Seema your-feed-healthcare Source Type: news

Biocon, Mylan win US court ruling in favour of insulin Glargine
US District Court of New Jersey found the device patent claims (US Patent No. 9526844) asserted by Sanofi against Biocon and Mylan ’s insulin Glargine product ‘not infringed’ and ‘invalid’ for lack of written description, said Biocon in a press statement. Semglee is co-developed with Mylan in the US. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - March 11, 2020 Category: Pharmaceuticals Source Type: news

Liver Antioxidant Response Impaired in Obesity-Associated Insulin Resistance Liver Antioxidant Response Impaired in Obesity-Associated Insulin Resistance
Liver macrophages inhibit the antioxidant response in obesity-associated insulin resistance, researchers report.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - March 10, 2020 Category: Pathology Tags: Diabetes & Endocrinology News Source Type: news

More choice means higher prices for American diabetics
Innovative drugs promise to make life easier — yet many people struggle to afford even insulin (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - March 10, 2020 Category: Pharmaceuticals Source Type: news

Poor countries struggle to get the insulin they need
High prices and patchy supplies make life hard for diabetics in the developing world (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - March 10, 2020 Category: Pharmaceuticals Source Type: news

Higher concentrations of IGF-1 are a probable cause of breast cancer
(European Society for Medical Oncology) A growth hormone called insulin-like growth factor-1 (IGF-1) is likely to play a role in the development of breast cancer, according to two complementary studies published in Annals of Oncology. One study looked at associations between blood levels of IGF-1 and the chances of the disease developing in over 200,000 women, and the second is a Mendelian randomization analysis of 265 variants of genes, which is able to show that IGF-1 is likely to play a causal role. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 10, 2020 Category: Cancer & Oncology Source Type: news

Suicide via intentional insulin overdose through first commercial hybrid closed-loop - Shah VN, Forlenza GP.
[Abstract unavailable] Language: en... (Source: SafetyLit)
Source: SafetyLit - March 9, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

The TikTok stars giving diabetes the needle
They can hula hoop and inject insulin at the same time. Meet the duo who are using social media to destigmatise diabetes. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - March 6, 2020 Category: Consumer Health News Source Type: news

Nurturing childhood homes can improve health in people with diabetes
Insulin and blood sugar monitoring are key to treating Type 1 diabetes, but a stable and nurturing home environment also may help long-term health in those with the disease, a new study has found. (Source: Health News - UPI.com)
Source: Health News - UPI.com - March 5, 2020 Category: Consumer Health News Source Type: news

New artificial pancreas improves blood sugar control in diabetes
A newly developed dual-hormone artificial pancreas regulates blood sugar better than a rapid insulin-alone artificial pancreas, according to research published inDiabetes Care.Medical Dialogues (Source: Society for Endocrinology)
Source: Society for Endocrinology - March 4, 2020 Category: Endocrinology Source Type: news

VA sued over veteran's death from wrongful insulin injection
A woman is suing the federal government over the 2018 death of her father from a wrongful insulin injection at a West Virginia veterans hospital (Source: ABC News: Health)
Source: ABC News: Health - March 3, 2020 Category: Consumer Health News Tags: Health Source Type: news

Two in Five Americans With Diabetes Report Financial Hardship Two in Five Americans With Diabetes Report Financial Hardship
Difficulty paying for diabetes medications is common among the nonelderly, and Medicare beneficiaries are paying high prices for insulin.Medscape Medical News (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - February 28, 2020 Category: Drugs & Pharmacology Tags: Diabetes & Endocrinology News Source Type: news

Should Physicians'Prescribe' Housing for the Homeless? Should Physicians'Prescribe' Housing for the Homeless?
California's governor says housing should be prescribed like insulin or antibiotics. But most agree that while stable housing can improve health, it's too complex to prescribe.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 28, 2020 Category: Consumer Health News Tags: Family Medicine/Primary Care News Source Type: news

Coronavirus: Forget Face Masks, Focus On Basics Needed For 2 Weeks
BOSTON (CBS) – As concerns about the spread of the novel coronavirus mount, many people are left wondering if there’s anything they can do. And no, the answer is not to get your hands on a face mask. Face masks are useful when worn by people who are already sick to prevent the spread of germs, but not very helpful for healthy people trying to avoid getting sick. So forget the face masks and focus on the basics. Read: Answers To Your Coronavirus Questions According to the U.S. Department of Homeland Security, one important step is to make sure you have everything you need at home in the event you have to sh...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - February 27, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Healthwatch Syndicated CBSN Boston Syndicated Local Coronavirus Dr. Mallika Marshall Source Type: news

Tart cherry supplements and juice can help lower heart disease and Type 2 diabetes risk, advise researchers
(Natural News) According to a recent study, tart cherry juice and supplements can help people with metabolic syndrome. A team of researchers from the University of Hertfordshire in the U.K. conducted a trial involving people with metabolic syndrome and found that consuming Montmorency tart cherries can reduce systolic blood pressure and insulin levels. What is metabolic syndrome? Metabolic syndrome... (Source: NaturalNews.com)
Source: NaturalNews.com - February 26, 2020 Category: Consumer Health News Source Type: news

Oramed Reports Positive Results in the Final Cohort of Its Phase 2b Oral Insulin Trial
Primary endpoints successfully met Results confirm significant clinical benefits of ORMD-0801 at lower dose treatment 0.95% (0.81% placebo adjusted) A1C reduction in patients treated once daily at 8mg Excellent safety profile Paves the way for ... Biopharmaceuticals, Drug Delivery, Endocrinology Oramed Pharmaceuticals, oral insulin, insulin, diabetes (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - February 26, 2020 Category: Pharmaceuticals Source Type: news

Metabolic health and weight management key to minimizing diabetes risk
(The North American Menopause Society (NAMS)) Increased fat distribution during menopause has long been shown to increase insulin resistance and the risk of diabetes. A new study based on data from the Women's Health Initiative (WHI) shows that being metabolically unhealthy increases diabetes risk, even in women of normal weight. Results are published online today in Menopause, the journal of The North American Menopause Society (NAMS). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2020 Category: International Medicine & Public Health Source Type: news

Neighborhood walkability and risk of gestational diabetes - Kew S, Ye C, Mehmood S, Hanley AJ, Sermer M, Zinman B, Retnakaran R.
OBJECTIVE: Higher neighborhood walkability has been associated with a lower risk of type 2 diabetes mellitus (T2DM) by promoting greater physical activity (thereby reducing weight and lowering insulin resistance). However, it is not known if walkability ma... (Source: SafetyLit)
Source: SafetyLit - February 26, 2020 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Insulin signaling suppressed by decoys
(Scripps Research Institute) The discovery of an insulin 'decoy' molecule from the lab of Matthew Gill, PhD, in Florida shakes up understanding of insulin signaling, with implications for diabetes, longevity and aging research. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 25, 2020 Category: International Medicine & Public Health Source Type: news

Type 2 diabetes symptoms: Skin that looks and feels this way could be a warning sign
TYPE 2 diabetes is the most common form of diabetes and occurs when blood sugar levels rise due to problems with insulin. To avoid complications, spotting symptoms is very important, and one sign to look out for is on the skin. (Source: Daily Express - Health)
Source: Daily Express - Health - February 24, 2020 Category: Consumer Health News Source Type: news

Managing Hypertriglyceridemia-Associated Acute Pancreatitis Managing Hypertriglyceridemia-Associated Acute Pancreatitis
When it comes to the management of hypertriglyceridemia-associated acute pancreatitis, is IV insulin or conservative treatment the better option?Journal of the Endocrine Society (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - February 24, 2020 Category: Intensive Care Tags: Diabetes & Endocrinology Journal Article Source Type: news

Medtech in a Minute: Recalls, Insulet CGM Partnerships, and More
Class I Recalls for Abbott and Medtronic Both Abbott Laboratories and Medtronic faced Class I Recalls last week. Abbott faced a recall of specific lots of its NC Trek RX Coronary Dilatation Catheter. Medtronic’s MiniMed Insulin Pump was the subject of a recall. Insulet Corners CGM Market with Two High Profile Collaborations Last week, Insulet revealed it had snared two partnerships that will help it continue its strong momentum in the continuous glucose monitoring (CGM) market. The Billerica, MA-based company signed agreements with both Abbott Laboratories and DexCom. Grail Keeps Cranking Out Milestones T...
Source: MDDI - February 22, 2020 Category: Medical Devices Authors: Omar Ford Tags: Business Source Type: news

Biocon gets 3 USFDA observations for insulin facility in Malaysia
USFDA had conducted a pre-approval inspection of Biocon's subsidiary Biocon Sdn BHd's manufacturing facility in Malaysia for Insulin Glargine between February 10 and 21. "At the conclusion of the inspection, the agency issued a Form 483 with three observations which we believe are procedural in nature," a Biocon spokesperson said in a regulatory filing. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - February 22, 2020 Category: Pharmaceuticals Source Type: news

Lipid signaling from beta cells can potentiate an inflammatory macrophage polarization
(University of Alabama at Birmingham) The insulin-producing beta cells in the pancreas unwittingly produce a signal that may aid their own demise in Type 1 diabetes, according to a study of the lipid signals that drive macrophage cells in the body to two different phenotypes of activated immune cells. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 21, 2020 Category: International Medicine & Public Health Source Type: news

Glycemic Control in T2DM Worse With Refusal of Insulin Therapy
THURSDAY, Feb. 20, 2020 -- For individuals with uncontrolled type 2 diabetes, those who decline insulin therapy have worse glycemic control, according to a study published online Feb. 20 in Diabetic Medicine. Alexander Turchin, M.D., from Brigham... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 20, 2020 Category: Pharmaceuticals Source Type: news

Patients frequently refuse insulin therapy, delaying blood sugar control
(Brigham and Women's Hospital) Investigators from Brigham and Women's Hospital find that more than 40% of patients refuse a physician's recommendation of insulin therapy. The study also finds that patients who decline insulin therapy had worse blood sugar control and it took them significantly longer to lower their blood sugar levels than patients who began insulin therapy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 20, 2020 Category: International Medicine & Public Health Source Type: news

Prescription Medications Can Be Found on Craigslist
WEDNESDAY, Feb. 19, 2020 -- Prescription medications, especially analog insulin, can be found on Craigslist, according to a research letter published online Feb. 17 in JAMA Internal Medicine. Akram Ahamed, from the University of Delaware in Newark,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 19, 2020 Category: Pharmaceuticals Source Type: news

Insulet Brings in 2 Big Partnerships with CGM Powerhouses Abbott and DexCom
Insulet has snared two partnerships that will help it continue its strong momentum in the continuous glucose monitoring (CGM) market. The Billerica, MA-based company and one of the 25 most attractive medtech firms on the M&A radar, announced it had signed agreements with both Abbott Laboratories and DexCom. The agreements center around Insulet’s Omnipod Horizon Automated Insulin Delivery (AID) System, which is in pivotal trials in the U.S. The Omnipod Horizon System will be integrated with Abbott’s Freestyle Libre 2, which has approval in Europe. The Freestyle Libre 2 has not yet rec...
Source: MDDI - February 19, 2020 Category: Medical Devices Authors: Omar Ford Tags: Digital Health Business Source Type: news

Abbott and Insulet Partner to Integrate Next-Generation Glucose Sensing and Automated Insulin Delivery Technologies for Seamless Diabetes Care
Collaboration will combine Abbott's leading continuous glucose monitoring (CGM) technology with Insulet's Omnipod Horizon™ Automated Insulin Delivery System to offer an accurate, easy-to-use, integrated digital health platform Integrated technology will... Devices, Monitoring, Drug Delivery, Endocrinology Abbott, Insulet , Omnipod Horizon, diabetes (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - February 19, 2020 Category: Pharmaceuticals Source Type: news

Abbott and Insulet Partner to Integrate Next-Generation Glucose Sensing and Automated Insulin Delivery Technologies for Seamless Diabetes Care
- Collaboration will combine Abbott's leading continuous glucose monitoring (CGM) technology with Insulet's Omnipod Horizon ™ Automated Insulin Delivery System to offer an accurate, easy-to-use, integrated digital health platform (Source: Abbott.com)
Source: Abbott.com - February 19, 2020 Category: Pharmaceuticals Source Type: news

Why Human Factors Terminology Needs Updating
Conclusion IEC 62366-1 leaves a chasm between Normal Use and Abnormal Use, so manufacturers might not consider some user actions to be “Use Errors” if these actions do not fit the IEC 62366-1 definition of use. In other words, Use Errors may go undetected, unaddressed, or unmitigated. To protect users and manufacturers, this gap must be closed: IEC 62366-1 should be updated to address user actions that do not fit the current definitions of Normal Use nor Abnormal Use. To mend this gap in IEC 62366-1, we suggest to: Re-define Abnormal Use in terms of abuse. Remove Normal Use. Remove the &...
Source: MDDI - February 19, 2020 Category: Medical Devices Authors: Kaivon Assani Tags: Design Source Type: news