Deltoid Muscle Brightness on Ultrasound May Be Linked With Diabetes Deltoid Muscle Brightness on Ultrasound May Be Linked With Diabetes
An unusually bright, or hyperechoic, deltoid muscle on ultrasound may be result of insulin resistance and thus a sign of diabetes, according to a new study.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 29, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

ViaCyte Secures $80 Million Financing to Advance Functional Cures for Insulin-Requiring Diabetes
Three financing initiatives announced over last three months secure combined commitments of over $100M to drive forward the Company's human cell therapy platform including its clinical-stage islet cell replacement product candidates Initial data from cl... Regenerative Medicine, Endocrinology, Venture Capital ViaCyte, islet replacement, diabetes, PEC-Direct, PEC-Encap (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - November 29, 2018 Category: Pharmaceuticals Source Type: news

How Can Nanotechnologies Aid Implantable Drug-Delivery Systems?
Implantable technologies have come a long way over the years, and advancements in micro and nanotechnologies have helped device developers continue to push the envelope even further. Within the realm of drug delivery, advances in nanotechnologies have consistently improved patient outcomes by enabling sustained drug delivery to help treat chronic conditions. These scalable technologies have even offered localized drug delivery that can further improve bioavailability. While many of these technologies offer a variety of opportunities, we’re still eagerly awaiting to see the impact of these advancements onc...
Source: MDDI - November 29, 2018 Category: Medical Devices Authors: Kristopher Sturgis Tags: BIOMEDevice San Jose Implants Source Type: news

More prescribing curbs mooted as gluten free scripts banned
NHS England has set out plans to curb the prescribing of items such as silk garments, bath oils, blood glucose testing strips, and needles for pre-filled and reusable insulin pens. (Source: Nursing Times)
Source: Nursing Times - November 28, 2018 Category: Nursing Source Type: news

Type 2 diabetes: Five alcoholic drinks to avoid to keep blood sugar levels normal
TYPE 2 diabetes is a common condition where the body can ’t control the amount of glucose in the blood and doesn’t respond to the hormone insulin properly. To keep the condition under control there are five alcoholic drinks you should avoid. (Source: Daily Express - Health)
Source: Daily Express - Health - November 28, 2018 Category: Consumer Health News Source Type: news

Insulin pumps cause more injuries than any other device in the US, study reveals
Over the last decade, insulin pumps and pump parts made by Medtronic Inc were subject to 20 manufacturer recalls and about 100 lawsuits alleging pump malfunctions. (Source: the Mail online | Health)
Source: the Mail online | Health - November 28, 2018 Category: Consumer Health News Source Type: news

Insulin pumps have most reported problems in FDA database
Insulin pumps are used by hundreds of thousands of diabetics around the word. Companies say they help them live normal lives. But AP investigation found that when it comes to medical devices, none have had more reported problems over the last decade (Source: ABC News: Health)
Source: ABC News: Health - November 27, 2018 Category: Consumer Health News Tags: Health Source Type: news

AP Investigation: Insulin Pumps have high number of injuries
Unlike other medical devices, problems with insulin pumps and their components have flown under the radar. Many of the problems are blamed on user error. Experts and doctors note the pumps are complicated devices requiring special training for patients. (Source: ABC News: Health)
Source: ABC News: Health - November 27, 2018 Category: Consumer Health News Tags: Health Source Type: news

Endocrine Society Advice on Insulin Dose Adjustment for Libre Endocrine Society Advice on Insulin Dose Adjustment for Libre
The Endocrine Society has issued guidance for patients with diabetes on how to use trend arrow data in FreeStyle Libre glucose monitors to adjust insulin following similar advice for Dexcom G5.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 27, 2018 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Insulin pumps linked to more reports of injury and death than any other medical device, records show
Insulin pumps are popular among Canadians with diabetes. The device is convenient and allows the user a greater degree of control over their blood sugar levels. But some experts warn that's precisely why it isn't necessarily the best — or safest — choice for all people with the condition. (Source: CBC | Health)
Source: CBC | Health - November 27, 2018 Category: Consumer Health News Tags: News/Health Source Type: news

Admelog (Insulin Lispro Injection) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 27, 2018 Category: Drugs & Pharmacology Source Type: news

FDA Gets out in Front of Injection Pen Errors
In recent years, our human factors researchers have seen a few persistent use errors in usability studies that involve injection pens. Many home users—patients and caregivers—encounter confusion when interacting with the shields covering the disposable needles that are attached to the pens. One error in particular is severe and prevalent enough to have raised the FDA’s concern. To address it, they have issued a labeling change request to manufacturers. Most of these home-use pen needles come with two shields: a tiny inner shield that loosely covers the needle itself and...
Source: MDDI - November 26, 2018 Category: Medical Devices Authors: T. Grant Leffingwell Tags: Design News Regulatory and Compliance Source Type: news

Valeritas touts use of insulin delivery device with physician-driven titration algorithm
Valeritas (NSDQ:VLRX) touted today the publication of a retrospective analysis showing that adults with Type 2 diabetes experienced improved glycemic control using the V-Go wearable insulin delivery device and a physician-driven titration algorithm. The proof-of-concept study was designed to assess the safety and efficacy of a doctor-driven insulin titration algorithm in adults who were prescribed V-Go. Researchers evaluated the participants’ clinical outcomes after four months. Get the full story at our sister site, Drug Delivery Business News. The post Valeritas touts use of insulin delivery device with physic...
Source: Mass Device - November 26, 2018 Category: Medical Devices Authors: Sarah Faulkner Tags: Diabetes Drug-Device Combinations Pharmaceuticals Wall Street Beat Valeritas Source Type: news

Medtronic ’ s insulin pumps highlighted in medtech injury report
A new report published this week by the International Consortium of Investigative Journalists and media organizations around the world took aim at medical device companies and the regulations that govern the $400 billion industry. And in a related report about Medtronic (NYSE:MDT), the authors zero in on the company’s diabetes unit and its insulin pumps. Over the last decade, Medtronic’s insulin pumps and its parts were linked to 20 recalls and 100 lawsuits, according to the report. The ICIJ analysis found that the company’s insulin pumps have accounted for 150,000 injuries a...
Source: Mass Device - November 26, 2018 Category: Medical Devices Authors: Sarah Faulkner Tags: Diabetes Drug-Device Combinations Featured Food & Drug Administration (FDA) Pharmaceuticals Recalls Regulatory/Compliance Wall Street Beat Medtronic Source Type: news

Insulin Needed for T2DM Tx Set to Increase & #62;20 Percent by 2030
MONDAY, Nov. 26, 2018 -- From 2018 to 2030, the insulin required to treat type 2 diabetes is expected to increase more than 20 percent, according to a study published online Nov. 20 in The Lancet Diabetes& Endocrinology. Sanjay Basu, Ph.D.,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 26, 2018 Category: Pharmaceuticals Source Type: news

Does More FDA Oversight Equal Better Compliance?
Since 2007, FDA has increased its annual number of medical device inspections by 46% and has increased annual inspections of foreign firms by 243%. In that timeframe, the agency also helped establish the Medical Device Single Audit Program, which has increased its oversight of foreign manufacturing facilities beyond the inspections the agency performs on its own. The question is, have these actions translated into improved quality compliance? The short answer, according to a new report issued by FDA's Center for Devices and Radiological Health (CDRH), is yes. According to the Medical Device Enforcement and Qual...
Source: MDDI - November 26, 2018 Category: Medical Devices Authors: Amanda Pedersen Tags: Regulatory and Compliance Source Type: news

Skin inflammation may increase diabetes risk
Research, presented at the Society for Endocrinology annual conference, suggests that psoriasis may cause insulin resistance and increase type-2 diabetes risk.Medical News Today (Source: Society for Endocrinology)
Source: Society for Endocrinology - November 23, 2018 Category: Endocrinology Source Type: news

Insulin-glucose infusion may lower neonatal hypoglycaemia risk
Research, presented at the Society for Endocrinology annual conference, suggests that an IV insulin-glucose infusion protocol, for gestational diabetes patients, lowers the risk of neonatal hypoglycaemia.Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - November 23, 2018 Category: Endocrinology Source Type: news

Looking at the AI Renaissance in Medtech
When I joined MD+DI nearly a year ago, I would hear smatterings about artificial intelligence and machine learning in medtech. But then something happened. By mid-February every other pitch I started receiving was AI-related. Conferences started delving into the AI topic. I even participated in a webinar hosted by Dave Saunders, CTO and Co-founder of Galen Robotics. It was clear to me that AI wasn’t just a buzzword, or some fancy marketing scribble used to catch a journalist’s attention. AI is something more than a trend. It’s going to be interwoven into the very fabric...
Source: MDDI - November 23, 2018 Category: Medical Devices Authors: Omar Ford Tags: Digital Health Source Type: news

Medical News Today: How to treat diabetes
Diabetes is an ongoing condition in which the body either produces too little insulin or does not use insulin effectively. Management includes artificial insulin and lifestyle adjustments. Read on to learn more. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 23, 2018 Category: Consumer Health News Tags: Diabetes Source Type: news

Medical News Today: What to know about type 1 diabetes
There are two main types of diabetes, and type 1 leads to insufficient production of insulin. This type is normally present from a young age and irreversible. Read on to learn about the symptoms, how to manage insulin production, and possible causes. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 23, 2018 Category: Consumer Health News Tags: Diabetes Type 1 Source Type: news

Medical News Today: Who discovered insulin?
Diabetes is a disorder centering around a deficiency or lack of insulin. The treatments available today would not have been possible without the discovery of insulin. Read on to learn more about the history of insulin and the controversy surrounding its development. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 23, 2018 Category: Consumer Health News Tags: Diabetes Source Type: news

Global insulin demands are set to skyrocket by more than 20% over the next 12 years
Millions of people in China, India and America will struggle to access the life-saving hormone by 2020. Part of the issue appears to be increased cost, which has spiked in recent years. (Source: the Mail online | Health)
Source: the Mail online | Health - November 22, 2018 Category: Consumer Health News Source Type: news

Diabetes type 2: Insulin SHORTAGE warning - where is likely to be affected?
DIABETES type 2 symptoms include weight loss, passing more urine than normal and feeling very tired. The number of cases worldwide is expected to rise over the coming years, but the availability of insulin may not be able to keep up. This is where is most likely to be affected by an insulin shortage. (Source: Daily Express - Health)
Source: Daily Express - Health - November 22, 2018 Category: Consumer Health News Source Type: news

40 million people with diabetes will be left without insulin by 2030
As the number of people living with diabetes continues to rise, the access to insulin needed to meet growing demand will fall short, a new study predicts. (Source: CNN.com - Health)
Source: CNN.com - Health - November 22, 2018 Category: Consumer Health News Source Type: news

Myofibroblast proliferation and heterogeneity are supported by macrophages during skin repair
During tissue repair, myofibroblasts produce extracellular matrix (ECM) molecules for tissue resilience and strength. Altered ECM deposition can lead to tissue dysfunction and disease. Identification of distinct myofibroblast subsets is necessary to develop treatments for these disorders. We analyzed profibrotic cells during mouse skin wound healing, fibrosis, and aging and identified distinct subpopulations of myofibroblasts, including adipocyte precursors (APs). Multiple mouse models and transplantation assays demonstrate that proliferation of APs but not other myofibroblasts is activated by CD301b-expressing macrophages...
Source: ScienceNOW - November 22, 2018 Category: Science Authors: Shook, B. A., Wasko, R. R., Rivera-Gonzalez, G. C., Salazar-Gatzimas, E., Lopez-Giraldez, F., Dash, B. C., Munoz-Rojas, A. R., Aultman, K. D., Zwick, R. K., Lei, V., Arbiser, J. L., Miller-Jensen, K., Clark, D. A., Hsia, H. C., Horsley, V. Tags: Cell Biology, Medicine, Diseases, Online Only r-articles Source Type: news

Half of the world's diabetics won't have insulin by 2030, study says
By 2030, about half of the 79 million adults around the globe predicted to have type 2 diabetes won't have access to insulin, a study said. (Source: Health News - UPI.com)
Source: Health News - UPI.com - November 21, 2018 Category: Consumer Health News Source Type: news

Insulin Need Set to Rise 20% by 2030, but Access May Be Limited Insulin Need Set to Rise 20% by 2030, but Access May Be Limited
Rising prevalence of type 2 diabetes means insulin requirements will increase around the globe, but access needs to improve substantially to meet demand, a mathematical model indicates.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 21, 2018 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

40 million people with diabetes will be left without insulin by 2030, study predicts
As the number of people living with diabetes continues to rise, the access to insulin needed to meet growing demand will fall short, a new study predicts. (Source: CNN.com - Health)
Source: CNN.com - Health - November 21, 2018 Category: Consumer Health News Source Type: news

Eating Disorders and the Brain
Eating disorders are biologically based brain illnesses influenced by environmental and psychological factors. Environmental risk factors for developing an eating disorder include weight and appearance pressures, media messaging, and weight bullying. Biological factors include dieting/food exposure, genetics, neurochemistry, neurobiology, and hormones (notably estrogen). Psychological factors include stress, life transitions, identity, trauma, anxiety, depression, and substance use. While risk factors predispose certain individuals to eating disorders, precipitating factors such as significantly altering how one eats or s...
Source: Psych Central - November 21, 2018 Category: Psychiatry Authors: Jillian Lampert, Ph.D., M.P.H., R.D., L.D., F.A.E.D. Tags: Anorexia Binge Eating Bulimia Bullying Children and Teens Eating Disorders Neuroscience Psychology Women's Issues Body Dysmorphia Body Image bulimia. food addiction Source Type: news

Insulet ’s Omnipod Dash system lands ISO cert for data security
Insulet (NSDQ:PODD) said this week that it won ISO 27001 certification for its Omnipod Dash product, meeting the international standard for best practice in an information security management system. The Billerica, Mass.-based company’s Omnipod Dash system wirelessly connects Insulet’s Personal Diabetes Manager with a tubeless, waterproof insulin pump. The PDM calculates how much insulin should be administered using blood glucose readings from the Contour Next One blood glucose meter. Get the full story at our sister site, Drug Delivery Business News. The post Insulet’s Omnipod Dash system ...
Source: Mass Device - November 21, 2018 Category: Medical Devices Authors: Sarah Faulkner Tags: Diabetes Drug-Device Combinations Pharmaceuticals Wall Street Beat Insulet Source Type: news

The number of people who need insulin may double by 2030
Research, published inLancet Diabetes and Endocrinology, suggests that the number of people who need insulin to manage their diabetes will double by 2030.  Telegraph (Source: Society for Endocrinology)
Source: Society for Endocrinology - November 21, 2018 Category: Endocrinology Source Type: news

Kisspeptin could be a treatment for type-2 diabetes
Research, presented at the Society for Endocrinology annual conference, suggests that kisspeptin can increase glucose-stimulated insulin secretion in men.Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - November 21, 2018 Category: Endocrinology Source Type: news

Medical News Today: An overview of insulin
Insulin is a hormone that plays a central role in controlling blood sugar levels in the body. People with diabetes produce either insufficient or ineffective insulin and often require shots of insulin to resume daily function. Read on to learn about the way insulin works. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 21, 2018 Category: Consumer Health News Tags: Diabetes Source Type: news

Millions left behind as diabetes drives surge in insulin demand
A global diabetes epidemic is fuelling record demand for insulin but tens of millions will not get the injections they need unless there is a dramatic improvement in access and affordability, a new study concluded on Wednesday. (Source: Reuters: Health)
Source: Reuters: Health - November 21, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Insulin shortage could affect 40 million people with type 2 diabetes
Millions worldwide may be unable to access the drug by 2030, scientists predictAbout 40 million people who will need insulin to manage their type 2 diabetes in 12 years ’ time will not get it unless access to the drug is significantly improved, according to new research.Diagnoses of type 2 diabetes are soaring worldwide, linked to the obesity epidemic. Not all of those diagnosed will need insulin, which is essential to keep people with type 1 diabetes alive, including UK prime minister Theresa May. Buta study in the Lancet Diabetes and Endocrinology journal shows that 79 million people with type 2 will need it by 203...
Source: Guardian Unlimited Science - November 21, 2018 Category: Science Authors: Sarah Boseley Health editor Tags: Diabetes Health Obesity Science World news Society Source Type: news

What Will Global Insulin Use Look Like by 2030?
(MedPage Today) -- More disability-adjusted life years may be averted if A1c targets are higher for older adults (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 20, 2018 Category: Cardiology Source Type: news

IDegLira vs Insulin Glargine U100 Plus Insulin Aspart IDegLira vs Insulin Glargine U100 Plus Insulin Aspart
Is IDegLira a more cost-effective treatment choice for type 2 diabetes than insulin glargine U100 plus insulin aspart?Endocrine Practice (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 20, 2018 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Embedded Hardware Technology: The Sure  Cure for Counterfeiting
Conclusion The technology discussed here is designed to be as resistant as possible from being cloned. While technology continues to advance, the capabilities of counterfeiters advance perhaps even faster. New, more robust ACF systems continue to be developed and deployed to ensure that medical devices remain secure and safe for patients and OEMs alike. (Source: MDDI)
Source: MDDI - November 20, 2018 Category: Medical Devices Authors: Paul Karazuba Tags: Software Source Type: news

Integrated proximal proteomics reveals IRS2 as a determinant of cell survival in ALK-driven neuroblastoma
Oncogenic anaplastic lymphoma kinase (ALK) is one of the few druggable targets in neuroblastoma, and therapy resistance to ALK-targeting tyrosine kinase inhibitors (TKIs) comprises an inevitable clinical challenge. Therefore, a better understanding of the oncogenic signaling network rewiring driven by ALK is necessary to improve and guide future therapies. Here, we performed quantitative mass spectrometry–based proteomics on neuroblastoma cells treated with one of three clinically relevant ALK TKIs (crizotinib, LDK378, or lorlatinib) or an experimentally used ALK TKI (TAE684) to unravel aberrant ALK signaling pathway...
Source: Signal Transduction Knowledge Environment - November 20, 2018 Category: Science Authors: Emdal, K. B., Pedersen, A.-K., Bekker-Jensen, D. B., Lundby, A., Claeys, S., De Preter, K., Speleman, F., Francavilla, C., Olsen, J. V. Tags: STKE Research Resources Source Type: news

Glucose binding molecule could transform the treatment of diabetes
Scientists from the University of Bristol have designed a new synthetic glucose binding molecule platform that brings us one step closer to the development of the world ’ s first glucose-responsive insulin which, say researchers, will transform the treatment of diabetes. (Source: University of Bristol news)
Source: University of Bristol news - November 19, 2018 Category: Universities & Medical Training Tags: Research; Faculty of Science, Faculty of Science, School of Chemistry; Press Release Source Type: news

Knee arthritis is not linked to insulin resistance and diabetes
Research, published inArthritis Care& Research, suggests that diabetes is not linked to the incidence of knee osteoarthritis.Med Page Today (Source: Society for Endocrinology)
Source: Society for Endocrinology - November 19, 2018 Category: Endocrinology Source Type: news

No Link Between Diabetes and Knee Osteoarthritis
(MedPage Today) -- Also no association between fasting glucose or insulin resistance (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - November 16, 2018 Category: Endocrinology Source Type: news

A New Study Says Low-Carb Diets May Help You Lose Weight. But Are Carbs Really So Bad For You?
A new study suggests that low-carb diets may help people keep weight off and even drop extra pounds, adding to the confusion about the health benefits — or detriments — of carbohydrates. For the study, which was published in The BMJ, researchers put 234 overweight adults on a 10-week weight-loss diet. More than half of them successfully lost about 10% of their body weight during that time. From there, they were then assigned to follow either a low-carb diet (20% of total calories from carbohydrates, 60% from fat), a moderate-carb diet (40% from carbs and fat) or a high-carb diet (60% from carbs, 20% from fat) f...
Source: TIME: Health - November 16, 2018 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Diet/Nutrition healthytime Source Type: news

Hot baths can lower insulin levels
Research, published in theJournal of Applied Physiology, suggests that taking hot baths can lower blood sugar and insulin levels that may lead to improved metabolic health. Daily Mail (Source: Society for Endocrinology)
Source: Society for Endocrinology - November 16, 2018 Category: Endocrinology Source Type: news

A gut bacterium as a fountain of youth? Well, let ’s start with reversing insulin resistance
Move over Bifidobacterium and Lactobacillus. There ’s a new health-promoting gut bacterium in town, and it’s called Akkermansia muciniphila.You will not find its benefits at the bottom of a yogurt cup. But a new study has identified more than one way to nurture its growth in the gut, and offered... (Source: Los Angeles Times - Science)
Source: Los Angeles Times - Science - November 15, 2018 Category: Science Authors: Melissa Healy Source Type: news

Check out these common herbs and spices that can decrease insulin resistance and lower blood sugar levels
(Natural News) Thanks to the to advent of modern medicine, many medicinal herbs and spices have been relegated to the back of kitchen cabinets and pantries. The truth is that herbs and spices hold far more healing power than the average pharmaceutical; whether it’s warding off the common cold, or battling blood sugar levels, natural... (Source: NaturalNews.com)
Source: NaturalNews.com - November 14, 2018 Category: Consumer Health News Source Type: news

How a Low-Carb Diet Might Help You Maintain a Healthy Weight
Adults who cut carbohydrates from their diets and replaced them with fat sharply increased their metabolisms. (Source: NYT Health)
Source: NYT Health - November 14, 2018 Category: Consumer Health News Authors: ANAHAD O ’ CONNOR Tags: Obesity Weight Diet and Nutrition Calories Carbohydrates Exercise Insulin Oils and Fats Source Type: news

On-demand biologics
(American Chemical Society) Many life-saving medicines, including insulin, antibodies and vaccines, are derived from living cells. These 'biologics' can be difficult to obtain and store on the battlefield or in remote areas. That's why scientists are trying to develop portable systems that can quickly manufacture small batches of protein therapeutics on demand, according to an article in Chemical& Engineering News (C&EN), the weekly news magazine of the American Chemical Society. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 14, 2018 Category: International Medicine & Public Health Source Type: news