Engineered 'suicide genes' prevent tumors in stem cell-derived beta cells
(Diabetes Research Institute Foundation) Scientists from the Diabetes Research Institute at the University of Miami have engineered a human pluripotent stem cell line containing two 'suicide genes' that induce cell death in all but the desired insulin-producing cells. This double fail-safe approach addresses the limitations of pluripotent stem cell-derived beta cells and opens the door to creating safe cell-replacement therapies for people living with type 1 diabetes. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 19, 2019 Category: International Medicine & Public Health Source Type: news

Novo Nordisk's soon-to-be-released insulin pens will connect to Glooko's diasend platform
This morning Glooko also announced that its diasend platform will be compatible with the Dexcom G6.   (Source: mobihealthnews)
Source: mobihealthnews - February 18, 2019 Category: Information Technology Source Type: news

Americans Cross Border Into Mexico to Buy Insulin at a Fraction of US Cost Americans Cross Border Into Mexico to Buy Insulin at a Fraction of US Cost
For one patient, a three-month supply of insulin is $3,700 in the U.S. versus $600 in Mexico. But is it legal?Kaiser Health News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 15, 2019 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Americans Going to Mexico to Buy Insulin at Fraction of US Cost Americans Going to Mexico to Buy Insulin at Fraction of US Cost
For one patient, a three-month supply of insulin is $3,700 in the U.S. versus $600 in Mexico. But is it legal?Kaiser Health News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 15, 2019 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

FDA Approves First Customizable Insulin Pump
FRIDAY, Feb. 15, 2019 -- The Tandem Diabetes Care t:Slim X2 insulin pump, which allows a patient to customize treatment, has been approved by the U.S. Food and Drug Administration. The new device is described as either an alternate controller... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 15, 2019 Category: Pharmaceuticals Source Type: news

First Interoperable Insulin Pump OK'd; Diabetes Scam; Linagliptin CV Outcomes
(MedPage Today) -- News and commentary from the endocrinology world (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - February 15, 2019 Category: Cardiology Source Type: news

Could Your IoT Device Put Patients at Risk?
The Internet of Things is driving incredible innovation in healthcare. “Almost any new innovative medical device is currently designed as a part of broader interconnected system,” Rami Muleys, head of application security business development at Positive Technologies, told MD+DI. “The main value of IoT is the convergence between different systems and the ability to exchange data between every device – from an insulin pump to a hospital bed.” Healthcare is consequently “a constantly changing landscape, especially sinc...
Source: MDDI - February 15, 2019 Category: Medical Devices Authors: Daphne Allen Tags: Business Source Type: news

#ICYMI: FDA authorizes first interoperable insulin pump intended to allow patients to customize treatment through their individual diabetes management devices. Read more here: https://go.usa.gov/xEUuM   #MedicalDevice #FDA
#ICYMI: FDA authorizes first interoperable insulin pump intended to allow patients to customize treatment through their individual diabetes management devices. Read more here: https://go.usa.gov/xEUuM  #MedicalDevice #FDA (Source: Food and Drug Adminstration (FDA): CDRHNew)
Source: Food and Drug Adminstration (FDA): CDRHNew - February 15, 2019 Category: Medical Devices Authors: ( at FDADeviceInfo) Source Type: news

Tandem wins interoperable claim for insulin pump from FDA
The FDA announced this week that it established Tandem Diabetes Care‘s (NSDQ:TNDM) t:slim X2 insulin pump as the first in a new category of devices called ‘Alternate Controller Enabled Infusion Pumps’ or ACE pumps. The newly-approved indication for Tandem’s t:slim X2 pump clears the device to communicate with compatible products, including insulin dosing software and continuous glucose monitors. Get the full story at our sister site, Drug Delivery Business News. The post Tandem wins interoperable claim for insulin pump from FDA appeared first on MassDevice. (Source: Mass Device)
Source: Mass Device - February 15, 2019 Category: Medical Devices Authors: Sarah Faulkner Tags: Diabetes Drug-Device Combinations Featured Food & Drug Administration (FDA) Pharmaceuticals Regulatory/Compliance Wall Street Beat tandemdiabetes Source Type: news

First Customizable Insulin Pump Approved
FRIDAY, Feb. 15, 2019 -- The Tandem Diabetes Care t-Slim X2 insulin pump, which allows a patient to customize treatment, has been approved by the U.S. Food and Drug Administration. " Diabetes is a complicated disease that requires close monitoring... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 15, 2019 Category: General Medicine Source Type: news

Type 2 diabetes: Working for this many hours per week may increase diabetes risk
TYPE 2 diabetes is caused by having too much sugar in the blood, which happens due to problems with the body ’s production of insulin. There are some risk factors which can increase the chance of this happening, and one study has revealed working for a certain number of hours per week may raise the risk. (Source: Daily Express - Health)
Source: Daily Express - Health - February 15, 2019 Category: Consumer Health News Source Type: news

Type 2 diabetes: Working 37.5 hours per week may increase diabetes risk, reveals study
TYPE 2 diabetes is caused by having too much sugar in the blood, which happens due to problems with the body ’s production of insulin. There are some risk factors which can increase the chance of this happening, and one study has revealed working for a certain number of hours per week may raise the risk. (Source: Daily Express - Health)
Source: Daily Express - Health - February 15, 2019 Category: Consumer Health News Source Type: news

The Lypla1 gene impacts obesity in a sex-specific manner
(Deutsches Zentrum fuer Diabetesforschung DZD) Susceptibility to obesity, insulin resistance and other cardio-metabolic traits may also be dependent on a person's sex. An international research team studied sex differences and sex-specific interaction with the genetic background in cardio-metabolic phenotypes. The researchers discovered, among other things, a sex-specific obesity locus of the Lypla1 gene, which is associated with human obesity. The results of the study have now been published in Cell Metabolism. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 15, 2019 Category: International Medicine & Public Health Source Type: news

FDA authorizes first interoperable insulin pump intended to allow patients to customize treatment through their individual diabetes management devices
(Source: Food and Drug Administration)
Source: Food and Drug Administration - February 14, 2019 Category: American Health Source Type: news

Can Americans travel to Mexico to buy insulin?
The cost of the drug can be significantly cheaper south of the border. (Source: ABC News: Health)
Source: ABC News: Health - February 14, 2019 Category: Consumer Health News Tags: Health Source Type: news

Why this mom traveled to Mexico for insulin
The cost of the drug can be significantly cheaper south of the border. (Source: ABC News: Health)
Source: ABC News: Health - February 14, 2019 Category: Consumer Health News Tags: Health Source Type: news

Human Pancreas Cells Can Be Made to Produce Insulin
When implanted into mice, the "pseudo-islets" helped treat the animals' diabetes symptoms. (Source: The Scientist)
Source: The Scientist - February 14, 2019 Category: Science Tags: News & Opinion Source Type: news

Metabolism, memory, and the role of insulin in the brain
(Source: NIDDK News)
Source: NIDDK News - February 14, 2019 Category: Endocrinology Source Type: news

Obesity Linked to Adverse Events in Children With Leukemia
Obesity ups risk for treatment - requiring hypertension, insulin - requiring hyperglycemia (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - February 13, 2019 Category: Cancer & Oncology Tags: Oncology, Pediatrics, Pharmacy, Journal, Source Type: news

Marine snail insulin may improve diabetes treatment
Research, published ineLife, suggests that insulin derived from marine snail venom could help to improve diabetes treatment. Newswise (Source: Society for Endocrinology)
Source: Society for Endocrinology - February 13, 2019 Category: Endocrinology Source Type: news

Oestrogen may reduce type-2 diabetes risk
Research, published inDiabetes, suggests that oestrogen decreases insulin resistance, which may be protective against type-2 diabetes. Science Daily (Source: Society for Endocrinology)
Source: Society for Endocrinology - February 13, 2019 Category: Endocrinology Source Type: news

The diabetics who’ve made their own new pancreas 
Like all of the 460,000 Brits with type 1 diabetes, Tim Street, has to constantly monitor his blood sugar levels and inject insulin many times a day to stay alive. But a new treatment has changed this. (Source: the Mail online | Health)
Source: the Mail online | Health - February 12, 2019 Category: Consumer Health News Source Type: news

Texas A & M-led study explores the role of estrogen in controlling Type 2 diabetes
(Texas A&M AgriLife Communications) The results of a recent Texas A&M University-led study provide insights into the mechanism by which estrogen can decrease insulin resistance and the production of glucose, reducing incidences of Type 2 diabetes mellitus. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 12, 2019 Category: International Medicine & Public Health Source Type: news

Study: Researchers develop ingestible capsule for insulin delivery
Image Credit: Felice Frankel A team of researchers from MIT developed an ingestible, blueberry-sized capsule that can deliver insulin orally. In animal models, the capsule lowered blood sugar levels and performed comparably with the traditional route of insulin delivery – injections. The capsule features a small needle made of freeze-dried, compressed insulin. The needle is attached to a compressed spring, which is held in place by a sugar disk. Once the capsule reaches the stomach, the sugar disk dissolves and the needle injects into the stomach wall. Get the full story at our sister site, Drug Delivery Bu...
Source: Mass Device - February 11, 2019 Category: Medical Devices Authors: Sarah Faulkner Tags: Diabetes Drug-Device Combinations Featured Pharmaceuticals Research & Development Brigham & Women's Hospital Massachusetts Institute of Technology National Institutes of Health (NIH) Novo Nordisk Source Type: news

Intense IV blood glucose control ‘doesn’t improve stroke outcomes’
Intravenous insulin does not improve stroke outcomes compared to standard blood glucose control using insulin shots, according to researchers. (Source: Nursing Times)
Source: Nursing Times - February 11, 2019 Category: Nursing Source Type: news

Humulin R U-500 Kwikpen (Insulin Human Injection for Subcutaneous Use) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 11, 2019 Category: Drugs & Pharmacology Source Type: news

Severe Familial Hypertriglyceridemia Severe Familial Hypertriglyceridemia
In this article, the successful treatment of severe familial hypertriglyceridemia using insulin and a special meal plan is described.Journal of the Endocrine Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 11, 2019 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Insulin pill might one day make treating diabetes a little less painful
The pill is about the size of a blueberry and it has worked in animals. (Source: ABC News: Health)
Source: ABC News: Health - February 10, 2019 Category: Consumer Health News Tags: Health Source Type: news

Medical News Today: Diabetes: Could a pill replace insulin injections?
Insulin injections are part of daily blood glucose management for many people with type 2 diabetes. Now, a new pill could spell the end for injections. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 10, 2019 Category: Consumer Health News Tags: Diabetes Type 2 Source Type: news

Lab-Grown Insulin-Producing Cells; Pot and Sperm; Insulin Pill?
(MedPage Today) -- News and commentary from the endocrinology world (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - February 8, 2019 Category: Cardiology Source Type: news

Morning Break: Injection-Free Insulin; Measles Outbreaks; Stinky Attraction
(MedPage Today) -- Health news and commentary from around the Web gathered by the MedPage Today staff (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - February 8, 2019 Category: Psychiatry Source Type: news

Insulin pill could treat diabetes patients
Research, published inScience, suggests that insulin-containing oral pills could replace injections, to help treat diabetes patients with a fear of needles.Guardian (Source: Society for Endocrinology)
Source: Society for Endocrinology - February 8, 2019 Category: Endocrinology Source Type: news

Potential new treatment for diabetes
Research, published inNucleic Acid Therapeutics, suggests that targeting a gene-silencing molecule improves insulin secretion in mice.MedicalXpress (Source: Society for Endocrinology)
Source: Society for Endocrinology - February 8, 2019 Category: Endocrinology Source Type: news

High-Tech Capsule Could One Day Replace Insulin Injections
Title: High-Tech Capsule Could One Day Replace Insulin InjectionsCategory: Health NewsCreated: 2/7/2019 12:00:00 AMLast Editorial Review: 2/8/2019 12:00:00 AM (Source: MedicineNet Diabetes General)
Source: MedicineNet Diabetes General - February 8, 2019 Category: Endocrinology Source Type: news

Milli-Needle Pill Developed to Deliver Insulin
Tested in preclinical models, device the size of a pea delivers a microinjection from within the stomach (Source: BWH News)
Source: BWH News - February 8, 2019 Category: Hospital Management Source Type: news

SHINE: No Improvement With Intense IV Glucose Control in Stroke SHINE: No Improvement With Intense IV Glucose Control in Stroke
Intense intravenous glucose control does not better improve functional outcomes after an ischemic stroke than standard subcutaneous insulin therapy — and may increase risk for hypoglycemia.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 7, 2019 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Diabetes patients could swallow tiny NEEDLES to deliver their insulin in drug breakthrough
A new study led by the Massachusetts Institute of Technology has found that a pill containing a tiny needle made of freeze-dried insulin can deliver as much of the medication as a traditional injection. (Source: the Mail online | Health)
Source: the Mail online | Health - February 7, 2019 Category: Consumer Health News Source Type: news

Pea-Sized Pill Delivers Insulin Shot From Inside The Stomach
WASHINGTON (AP) — Scientists have figured out how to hide a shot inside a pea-sized pill — creating a swallowable gadget, inspired by a tortoise shell, that can inject medicines like insulin from inside the stomach. Patients usually prefer oral treatment, and comply with it better, but many compounds, including insulin for diabetes, can’t survive the harsh trip through the digestive system. The new invention, reported Thursday by a Massachusetts Institute of Technology-led research team, has been tested only in animals so far. But if it pans out, it might offer a work-around to make not just insulin but a...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - February 7, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Syndicated Local Diabetes insulin MIT Source Type: news

Diabetes pill could inject insulin directly into stomach wall
Researchers from MIT and Novo Nordisk have tested tortoise-inspired oral insulin system (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - February 7, 2019 Category: Pharmaceuticals Source Type: news

Pill inspired by leopard tortoise could replace diabetic injections
Capsule shape based on domed shell ensures insulin needle within aims at stomach wallScientists have developed a “needle pill” that could allow diabetics to take insulin without the need for daily injections.The pea-sized capsule contains a small needle made of solid, compressed insulin, which is injected into the stomach wall after the capsule has been swallowed.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - February 7, 2019 Category: Science Authors: Hannah Devlin Science correspondent Tags: Science Diabetes Society World news Source Type: news

Researchers Are Working on a Surprising Way to Deliver Insulin Without an Injection: Swallowing the Needle
Needles aren’t popular. For people with type 1 diabetes (and some with type 2 diabetes) that can be a problem, since treatment requires regular injections with insulin. Now, researchers at MIT have come up with a novel way to one day eliminate the need for injections: with a tiny swallowable device that can automatically inject insulin directly into the stomach wall. In a report published in Science, Robert Langer and Giovanni Traverso describe what they call a self-orienting millimeter scale applicator, or SOMA, that they developed to make injecting drugs easier. So far, SOMA has only been tested in animals. Roughly...
Source: TIME: Health - February 7, 2019 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized diabetes healthytime Source Type: news

A High-Tech Pill to End Drug Injections
Engineers have developed a tiny robotic capsule that injects insulin once it lands in the stomach. (Source: NYT Health)
Source: NYT Health - February 7, 2019 Category: Consumer Health News Authors: GINA KOLATA Tags: Insulin Turtles and Tortoises Digestive Tract Biotechnology and Bioengineering Drugs (Pharmaceuticals) Brigham and Women's Hospital Harvard University Massachusetts Institute of Technology Novo Nordisk A/S Science (Journal) your-feed-s Source Type: news

Bigfoot Biomedical, Owen Mumford ink deal for pen needles
Bigfoot Biomedical said today that it inked a commercial supply deal to include Owen Mumford‘s Pentips line of pen needles with Bigfoot’s injection system subscription bundles. Milpitas, Calif.-based Bigfoot is working on monthly subscription packages for people with insulin-requiring diabetes. The company said it selected Owen Mumford’s pen needle because of the needle’s compatibility with all disposable insulin pens and availability in popular lengths and gauges. Get the full story at our sister site, Drug Delivery Business News. The post Bigfoot Biomedical, Owen Mumford ink deal for pen...
Source: Mass Device - February 7, 2019 Category: Medical Devices Authors: Sarah Faulkner Tags: Business/Financial News Diabetes Drug-Device Combinations Featured Pharmaceuticals Bigfoot Biomedical owenmumford Source Type: news

High-Tech Capsule Could One Day Replace Insulin Injections
THURSDAY, Feb. 7, 2019 -- For people with type 2 diabetes, could the days of having to jab themselves with a needle whenever they need insulin be over? It's now a distinct possibility, say researchers who have developed a capsule that can deliver... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 7, 2019 Category: General Medicine Source Type: news

New pill can deliver insulin
An MIT-led research team has developed a drug capsule that could be used to deliver oral doses of insulin, potentially replacing the injections that people with type 2 diabetes have to give themselves every day. About the size of a blueberry, the capsule contains a small needle made of compressed insulin, which is injected after the capsule reaches the stomach. (Source: World Pharma News)
Source: World Pharma News - February 7, 2019 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

NIH study provides answer to long-held debate on blood sugar control after stroke
(NIH/National Institute of Neurological Disorders and Stroke) Doctors all over the world have debated whether intensive glucose management, which requires the use of IV insulin to bring blood sugar levels down to 80-130 mg/dL, or standard glucose control using insulin shots, which aims to get glucose below 180 mg/dL, lead to better outcomes after stroke. Primary results from the Stroke Hyperglycemia Insulin Network Effort (SHINE) study, a large, multisite clinical study provide a clear answer to that question. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 7, 2019 Category: International Medicine & Public Health Source Type: news

Anti-microRNAs are possible new therapeutic target for type 2 diabetes
(Mary Ann Liebert, Inc./Genetic Engineering News) Researchers have shown that targeted silencing of microRNA-132, which is over-expressed in type 2 diabetes, can result in improved insulin secretion and reduced blood glucose in mice and increased insulin secretion in isolated human islet cells. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 7, 2019 Category: International Medicine & Public Health Source Type: news

An ingestible self-orienting system for oral delivery of macromolecules
Biomacromolecules have transformed our capacity to effectively treat diseases; however, their rapid degradation and poor absorption in the gastrointestinal (GI) tract generally limit their administration to parenteral routes. An oral biologic delivery system must aid in both localization and permeation to achieve systemic drug uptake. Inspired by the leopard tortoise’s ability to passively reorient, we developed an ingestible self-orienting millimeter-scale applicator (SOMA) that autonomously positions itself to engage with GI tissue. It then deploys milliposts fabricated from active pharmaceutical ingredients direct...
Source: ScienceNOW - February 7, 2019 Category: Science Authors: Abramson, A., Caffarel-Salvador, E., Khang, M., Dellal, D., Silverstein, D., Gao, Y., Frederiksen, M. R., Vegge, A., Hubalek, F., Water, J. J., Friderichsen, A. V., Fels, J., Kirk, R. K., Cleveland, C., Collins, J., Tamang, S., Hayward, A., Landh, T., Buc Tags: Engineering, Medicine, Diseases reports Source Type: news

Eli Lilly backs U.S. proposal on drug rebates to lower costs
Eli Lilly and Co on Wednesday embraced a U.S. government proposal to end a decades-old system of rebates drugmakers make to industry middlemen, saying it could lower the cost of insulin and other prescription drugs for patients. (Source: Reuters: Health)
Source: Reuters: Health - February 6, 2019 Category: Consumer Health News Tags: healthNews Source Type: news