Vegan Diet Alters Microbiome and Insulin Sensitivity, Drops Weight Vegan Diet Alters Microbiome and Insulin Sensitivity, Drops Weight
Adopting a vegan diet seems to alter the gut microbiome and improve insulin sensitivity with associated weight loss, compared to eating conventionally even with no direction to restrict calorie intake.Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - September 17, 2019 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news

With a backup to the backup, insulin makers say they're primed for Brexit
For two men trained as scientists, the bosses of Britain's major insulin providers have had to become experts in ferry schedules, trucking laws and warehouse capacity as they seek to guarantee the supply of life-saving drugs through a chaotic Brexit. (Source: Reuters: Health)
Source: Reuters: Health - September 17, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

Collaboration Makes the Diabetes World Go & #039;Round
In the world of diabetes technologies, collaboration is the name of the game. Medtronic and Novo Nordisk are working together to integrate insulin dosing data from future Novo Nordisk smart insulin pens into continuous glucose monitoring (CGM) devices from Medtronic, such as the Guardian Connect system shown above. At the same time, Abbott and Sanofi will be working on tools that combine Abbott's FreeStyle Libre technology with Sanofi's insulin dosing information. "We see incredible power in combining a variety of data points to drive insights that help people living with diabetes make more informed decisions around m...
Source: MDDI - September 17, 2019 Category: Medical Devices Authors: Amanda Pedersen Tags: Business Source Type: news

Factbox: Britain's insulin providers prepare for Brexit fallout
With Britain sourcing the vast majority of the insulin needed by its 1 million diabetics from overseas, its biggest providers have had to restructure their supply chains in case a chaotic Brexit disrupts the normal arteries of trade. (Source: Reuters: Health)
Source: Reuters: Health - September 17, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

Abbott ’s FreeStyle Libre Catches Sanofi’s Eye in New Collaboration
Two powerhouses in pharma and medtech are working together to help people with diabetes better manage their condition. Abbott Laboratories and Sanofi will collaborate to integrate glucose sensing and insulin delivery technologies. The two companies will take an innovative approach to connected care by developing tools that combine the Abbott Park, Il-based company’s FreeStyle Libre technology with Paris-based Sanofi′s insulin dosing information. Initially, the collaboration enables data sharing, at the consent of the user, between Abbott′s FreeStyle Libre mobile app and...
Source: MDDI - September 17, 2019 Category: Medical Devices Authors: Omar Ford Tags: IVD Business Source Type: news

S.W. Washington biotech continues to grow rapidly
AbSci, the Vancouver, Wash.-based biotech startup that is developing an insulin-related technology, continues to experience healthy growth. The company is in the process of doubling its space in downtown Vancouver to 11,000 square feet, or the entire floor of its building. And AbSci is hiring 14 more employees, for a total of 45 by the end of the year, said founder and CEO Sean McClain. The positions span the marketing and business de velopment side of the business, along with the scientific. AbSci… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - September 16, 2019 Category: Biotechnology Authors: Elizabeth Hayes Source Type: news

S.W. Washington biotech continues to grow rapidly
AbSci, the Vancouver, Wash.-based biotech startup that is developing an insulin-related technology, continues to experience healthy growth. The company is in the process of doubling its space in downtown Vancouver to 11,000 square feet, or the entire floor of its building. And AbSci is hiring 14 more employees, for a total of 45 by the end of the year, said founder and CEO Sean McClain. The positions span the marketing and business de velopment side of the business, along with the scientific. AbSci… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - September 16, 2019 Category: Pharmaceuticals Authors: Elizabeth Hayes Source Type: news

Get a nutty treat and improve your cholesterol levels with tartary buckwheat
(Natural News) In a recent study which appeared in Nutrition Research, researchers from China found that tartary buckwheat, a crop widely grown in Asia, can help improve insulin levels in people with Type 2 diabetes. They also revealed that eating this type of buckwheat can lead to reduced bad cholesterol levels. To test whether tartary buckwheat can help... (Source: NaturalNews.com)
Source: NaturalNews.com - September 16, 2019 Category: Consumer Health News Source Type: news

Abbott and Sanofi Partner to Integrate Glucose Sensing and Insulin Delivery Technologies to Help Change the Way Diabetes is Managed
- Collaboration aims to provide a connected device experience for millions of people living with diabetes using insulin (Source: Abbott.com)
Source: Abbott.com - September 16, 2019 Category: Pharmaceuticals Source Type: news

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Landon Johnson,a 23-year-old diabetic who is running out of insulin and can't afford more, tells CNN affiliate WTVF he feels like he will die before he turns 30. (Source: CNN.com - Health)
Source: CNN.com - Health - September 14, 2019 Category: Consumer Health News Source Type: news

Hurricane Dorian Is Gone. But the Bahamas Still Faces a Big Risk From Infectious Disease
Hurricane Dorian’s 185 mph winds and punishingly slow pace smashed entire neighborhoods in the Bahamas, killing at least 50 people. But now, Bahamians are facing a different kind of threat. The lack of access to toilets, clean water and medications puts tens of thousands at risk for disease, public health experts warn. Bahamians in the hardest-hit areas are already suffering from cuts and gashes caused by widespread debris and wreckage. But now aid groups are saying survivors are beginning to show signs of gastrointestinal issues from contaminated water. Those with chronic illnesses are struggling without access to t...
Source: TIME: Health - September 12, 2019 Category: Consumer Health News Authors: Sanya Mansoor Tags: Uncategorized Bahamas Infectious Disease onetime weather Source Type: news

Medical News Today: What is regular insulin?
We describe how much regular insulin to take, potential side effects, and other considerations. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 11, 2019 Category: Consumer Health News Tags: Diabetes Source Type: news

Insulin delivery drug could help fight brain cancer
The compound molecule surfen was able to block the growth and spread of glioblastoma, tumors that reaches throughout healthy brain tissue, according to research published Wednesday in FASEB Journal. (Source: Health News - UPI.com)
Source: Health News - UPI.com - September 11, 2019 Category: Consumer Health News Source Type: news

Insulin Pump Therapy Use Has Increased Since 1995
WEDNESDAY, Sept. 11, 2019 -- Insulin pump usage has increased since 1995, especially among patients aged younger than 15 years, according to a study published online Sept. 5 in Diabetes Care. Louisa van den Boom, M.D., from Clementine Children's... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - September 11, 2019 Category: Pharmaceuticals Source Type: news

Insulin therapy response predicted by insulin sensitivity and adiponectin level
Youths with obesity and type 2 diabetes who had greater insulin sensitivity and higher levels of adiponectin displayed better response to insulin therapy, according to a study published inPediatric Diabetes.Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - September 11, 2019 Category: Endocrinology Source Type: news

Existing drug could treat aggressive brain cancer
A research team from the University of Georgia's Regenerative Bioscience Center has found that a compound molecule used for drug delivery of insulin could be used to treat glioblastoma, an aggressive, usually fatal form of brain cancer. Glioblastoma, also known as GBM, is a fast-growing, web-like tumor that arises from supportive tissue around the brain and resists surgical treatment. (Source: World Pharma News)
Source: World Pharma News - September 10, 2019 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Novo Nordisk to cut insulin prices in the U.S.
Novo Nordisk will offer cheaper insulin to U.S. diabetics, the Danish drugmaker said on Friday, in response to criticism over the high price of the medication and after similar moves by rivals Sanofi and Eli Lilly. (Source: Reuters: Health)
Source: Reuters: Health - September 6, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

Trigger for type 1 diabetes in mice identified
According to a new study published in the journalScience Immunology, a mechanistic switch in specific anti-insulin T cells has been linked to the destruction of insulin and onset of diabetes in mice.MedicalNewsToday (Source: Society for Endocrinology)
Source: Society for Endocrinology - September 6, 2019 Category: Endocrinology Source Type: news

New proteins found in transcriptional factor complex in beta cells
New proteins discovered in the transcription factor complex that maintain beta cell function may contribute to reduced insulin release, according to a study published in theJournal of Biological Chemistry.Scienmag (Source: Society for Endocrinology)
Source: Society for Endocrinology - September 6, 2019 Category: Endocrinology Source Type: news

Medical News Today: Scientists identify a trigger for type 1 diabetes in mice
Scientists discover a previously unknown switch that causes immune cells to begin destroying insulin, resulting in the onset of type 1 diabetes. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 6, 2019 Category: Consumer Health News Tags: Diabetes Type 1 Source Type: news

Early insulin recognition by T cells
(Source: ScienceNOW)
Source: ScienceNOW - September 5, 2019 Category: Science Authors: Williams, I. Tags: twis Source Type: news

Polycystic Ovary Syndrome Awareness Month
September is   Polycystic Ovary Syndrome Awareness Month and is an excellent time to focus on the latest Cochrane evidence.Polycystic ovary syndrome (PCOS) is a very common condition affecting 8% to 13% of women. Being overweight worsens all clinical features of PCOS. These clinical features include reproductive issues such as reduced frequency of ovulation and irregular menstrual cycles, reduced fertility, polycystic ovaries onultrasound and high levels of male hormones such as testosterone, which can cause unwanted facial or body hair growth and acne. PCOS is also associated with metabolic features, withrisk factors...
Source: Cochrane News and Events - September 3, 2019 Category: Information Technology Authors: Muriah Umoquit Source Type: news

Weight-Loss Surgery Dramatically Lowers the Risk of Early Death, a New Study Finds
For decades, doctors have known that losing weight can significantly lower risk of heart disease and by extension, reduce the risk of dying from heart-related events such as stroke and heart attack. Studies have shown that both lifestyle changes including diet and exercise as well as medications and weight-loss surgery can improve heart disease risk factors such as obesity and diabetes, for example, but data supporting the benefits of any of these approaches in actually lowering rates of heart events such as heart attack and atrial fibrillation, or in reducing early deaths from heart disease, have been less robust. The dat...
Source: TIME: Health - September 2, 2019 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized diabetes Heart Disease Source Type: news

USFDA issues response letter for new drug application for insulin glargine: Biocon
Biocon is confident of addressing these observations through a corrective and preventive action plan in a timely manner, it added. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - August 31, 2019 Category: Pharmaceuticals Source Type: news

West Virginia VA under investigation after 10 patients died following unneeded insulin injections
Authorities are investigating 10 deaths at the Louis A Johnson VA Medical Center in Clarksburg, West Virginia, after the patients died following unnecessary insulin injections. (Source: the Mail online | Health)
Source: the Mail online | Health - August 28, 2019 Category: Consumer Health News Source Type: news

Eating breakfast will give you energy and jumpstart your metabolism
(Natural News) Breakfast is often considered the most important meal of the day, but not everyone benefits from eating breakfast. A study published in the Journal of Physiology revealed that eating breakfast directly affects how fat cells function in the body by changing the activity of genes involved in fat metabolism and insulin resistance. For the... (Source: NaturalNews.com)
Source: NaturalNews.com - August 26, 2019 Category: Consumer Health News Source Type: news

Fatty Liver or Visceral Fat and Insulin Resistance Fatty Liver or Visceral Fat and Insulin Resistance
Findings from a new study suggest that fatty liver may be a better marker than visceral fat accumulation for predicting insulin resistance.Journal of the Endocrine Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 23, 2019 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Biocon's Malaysian arm gets EU GMP certification for insulin manufacturing facility
The integrated insulins facility in Malaysia manufactures drug substance and drug products in vials, cartridges, and insulin delivery devices was inspected in May 2019. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - August 22, 2019 Category: Pharmaceuticals Source Type: news

One in Four Patients Concerned About Diabetes Drug Costs One in Four Patients Concerned About Diabetes Drug Costs
Although the report did not identify insulin specifically, it did show how age, gender, and insurance status affected two main strategies patients with diabetes used to cut medication costs.Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - August 21, 2019 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news

The Keto Diet Is Popular, but Is It Good for You?
Low-carb, high-fat eating can lead to weight loss, but scientists debate the long-term effects on health. (Source: NYT Health)
Source: NYT Health - August 20, 2019 Category: Consumer Health News Authors: Anahad O ’Connor Tags: Obesity Diet and Nutrition Weight Diabetes Insulin Cholesterol Sugar Carbohydrates Exercise Calories Oils and Fats Vegetables Source Type: news

Type 2 diabetes: The big sign in your breath that could indicate you might have condition
TYPE 2 diabetes is a condition characterised by high blood sugar, insulin resistance, and relative lack of insulin. A person ’s breath can indicate if they are risk of developing the condition. (Source: Daily Express - Health)
Source: Daily Express - Health - August 17, 2019 Category: Consumer Health News Source Type: news

Type 2 diabetes: The big sign in your breath that could indicate you might have the condit
TYPE 2 diabetes is a condition characterised by high blood sugar, insulin resistance, and relative lack of insulin. A person ’s breath can indicate if they are risk of developing the condition. (Source: Daily Express - Health)
Source: Daily Express - Health - August 16, 2019 Category: Consumer Health News Source Type: news

Diabetes and psychosis audits: recommendations for commissioners
The Healthcare Quality Improvement Partnership has published the results of audits of insulin pump treatment for patients with type 1 diabetes and early intervention in psychosis. (Source: NHS Networks)
Source: NHS Networks - August 16, 2019 Category: UK Health Source Type: news

Medical News Today: How diet can alter the gut, leading to insulin resistance
A new study looks to mice and humans to find out more about the mechanisms through which diet can lead to insulin resistance, a key feature of diabetes. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 15, 2019 Category: Consumer Health News Tags: Diabetes Type 2 Source Type: news

Is Software the & #039;Weak Link & #039; in Medical Device Safety?
Software is a weak link for medical devices, according to Stericycle Expert Solutions' second-quarter recall index. The report found software issues to be the top cause of medical device recalls for the 13th straight quarter . "As we become increasingly reliant on AI and data collection, software becomes an even bigger vulnerability for patients, physicians, and wrongdoers," said Chris Harvey, director of recall solutions at Stericycle. "If the software that is used to operate a device is inadequate, how can we be sure that it is protected from cybersecurity vulnerabilities? Add to th...
Source: MDDI - August 14, 2019 Category: Medical Devices Authors: Amanda Pedersen Tags: Regulatory and Compliance Source Type: news

Obesity linked to loss of gut antibody, increased insulin resistance
Obesity may cause a gut bacteria known as immunoglobulin A to leak through stomach tissue, leading to inflammation that causes the body to develop insulin resistance. (Source: Health News - UPI.com)
Source: Health News - UPI.com - August 13, 2019 Category: Consumer Health News Source Type: news

Supplements to balance your hormones naturally
(Natural News) PCOS, short for polycystic ovary syndrome, is a hormonal disorder that affects as many as 10 percent of women. Women suffering from PCOS mainly experience insulin resistance and have too much of the male hormone androgen. Additionally, PCOS interferes with their appearance, fertility, menstrual cycle, metabolism, and mood. Many women with this condition... (Source: NaturalNews.com)
Source: NaturalNews.com - August 13, 2019 Category: Consumer Health News Source Type: news

Muscle-generated BDNF is a sexually dimorphic myokine that controls metabolic flexibility
The ability of skeletal muscle to switch between lipid and glucose oxidation for ATP production during metabolic stress is pivotal for maintaining systemic energy homeostasis, and dysregulation of this metabolic flexibility is a dominant cause of several metabolic disorders. However, the molecular mechanism that governs fuel selection in muscle is not well understood. Here, we report that brain-derived neurotrophic factor (BDNF) is a fasting-induced myokine that controls metabolic reprograming through the AMPK/CREB/PGC-1α pathway in female mice. Female mice with a muscle-specific deficiency in BDNF (MBKO mice) were u...
Source: Signal Transduction Knowledge Environment - August 13, 2019 Category: Science Authors: Yang, X., Brobst, D., Chan, W. S., Tse, M. C. L., Herlea-Pana, O., Ahuja, P., Bi, X., Zaw, A. M., Kwong, Z. S. W., Jia, W.-h., Zhang, Z.-g., Zhang, N., Chow, S. K. H., Cheung, W. H., Louie, J. C. Y., Griffin, T. M., Nong, W., Hui, J. H. L., Du, G.-h., Noh Tags: STKE Research Articles Source Type: news

How a Community Paramedics Program Can Help Keep Emergencies at Bay
Photo UnitedHealthcare The Milwaukee fire department is getting involved before an emergency happens. You might usually think of your city’s fire department as being first on the scene during an intense situation, with flashing lights and sirens. But what about a fire department that gets involved before an emergency happens? That’s exactly what’s happening in Milwaukee. Take Mary*, for example. She called 911 several times a week, due to issues related to her diabetes. In order to find a new solution, the Milwaukee Fire Department (MFD) enrolled her in the Community Paramedics Program...
Source: JEMS Patient Care - August 12, 2019 Category: Emergency Medicine Tags: Ambulances & Vehicle Ops Patient Care Press Releases Source Type: news

How a Community Paramedics Program Can Help Keep Emergencies at Bay
Photo UnitedHealthcare The Milwaukee fire department is getting involved before an emergency happens. You might usually think of your city’s fire department as being first on the scene during an intense situation, with flashing lights and sirens. But what about a fire department that gets involved before an emergency happens? That’s exactly what’s happening in Milwaukee. Take Mary*, for example. She called 911 several times a week, due to issues related to her diabetes. In order to find a new solution, the Milwaukee Fire Department (MFD) enrolled her in the Community Paramedics Program...
Source: JEMS Operations - August 12, 2019 Category: Emergency Medicine Tags: Ambulances & Vehicle Ops Patient Care Press Releases Source Type: news

US patients struggle to obtain Eli Lilly’s half-price insulin
Cheaper option was unveiled shortly before company was grilled by Congress about soaring prices (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - August 11, 2019 Category: Pharmaceuticals Source Type: news

The Challenges of Securing and Protecting Medical Devices
With increasing cyber-attacks and lives (literally) at stake, the medical device community is taking a serious look at how manufacturers can embed security best practices into their processes and devices. In fact, the medical device makers we talk to recognize the need for a security-first approach. Security doesn’t happen by mistake, but rather by design. That design ensures data protection, flexibility to support product longevity and unique device identification. Cryptographic considerations have become critically important in medical devices to guard data streams that travel to and from connected medi...
Source: MDDI - August 9, 2019 Category: Medical Devices Authors: Chris Hickman Tags: Business Digital Health Source Type: news

Initiation and Titration of Basal Insulin in Primary Care Initiation and Titration of Basal Insulin in Primary Care
Learn strategies to minimize weight gain and hypoglycemia associated with second-generation basal insulins.Journal of the American Board of Family Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 9, 2019 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

27-year-old diabetic man dies after switching to a cheaper insulin 
Josh Wilkerson was kicked off his family insurance automatically when he turned 26 and could no longer afford the insulin he used for diabetes type 1 diabetes. After starting a cheaper one, he died. (Source: the Mail online | Health)
Source: the Mail online | Health - August 6, 2019 Category: Consumer Health News Source Type: news

The kinase PKD3 provides negative feedback on cholesterol and triglyceride synthesis by suppressing insulin signaling
Hepatic activation of protein kinase C (PKC) isoforms by diacylglycerol (DAG) promotes insulin resistance and contributes to the development of type 2 diabetes (T2D). The closely related protein kinase D (PKD) isoforms act as effectors for DAG and PKC. Here, we showed that PKD3 was the predominant PKD isoform expressed in hepatocytes and was activated by lipid overload. PKD3 suppressed the activity of downstream insulin effectors including the kinase AKT and mechanistic target of rapamycin complex 1 and 2 (mTORC1 and mTORC2). Hepatic deletion of PKD3 in mice improved insulin-induced glucose tolerance. However, increased in...
Source: Signal Transduction Knowledge Environment - August 6, 2019 Category: Science Authors: Mayer, A. E., Löffler, M. C., Loza Valdes, A. E., Schmitz, W., El-Merahbi, R., Viera, J. T., Erk, M., Zhang, T., Braun, U., Heikenwalder, M., Leitges, M., Schulze, A., Sumara, G. Tags: STKE Research Articles Source Type: news

States probe Eli Lilly over insulin prices
Eli Lilly has been hit with a subpoena from the New York Attorney General ’s Office over the pricing and sales of its insulin treatments. (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - August 5, 2019 Category: Pharmaceuticals Source Type: news

Fasting improves insulin function
Overweight or obese adults can improve their insulin resistance by fasting on alternate days, according to research published inObesity.Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - August 5, 2019 Category: Endocrinology Source Type: news

Hyperinsulinemia linked to pancreatic cancer risk
Lowering insulin levels in a mouse model prone to developing pancreatic cancer reduced the incidence of the disease, according to a Canadian study published inCell Metabolism.Medical Xpress (Source: Society for Endocrinology)
Source: Society for Endocrinology - August 5, 2019 Category: Endocrinology Source Type: news

High insulin levels may bring on pancreatic cancer
Researchers bred mice that were genetically unable to produce excess insulin with mice susceptible to cancer development. The resulting mice had the same pancreatic cancer mutation found in 90 percent of human patients. (Source: Health News - UPI.com)
Source: Health News - UPI.com - August 2, 2019 Category: Consumer Health News Source Type: news

Dexcom CEO: The Future Is CGM First, and That Future Is Here
While attending the American Diabetes Association (ADA) conference in June, two conclusions became increasingly clear, said DexCom CEO Kevin Sayer. First, awareness of real-time continuous glucose monitoring (CGM) is quickly progressing and driving CGM toward standard-of-care status. Second, DexCom is just scratching the surface of the potential for CGM, he said. "We have gone on record for years telling [people] that the future is CGM first and we believe that future is here," Sayer said during the company's second-quarter earnings call, transcribed by SeekingAlpha.Â&nbs...
Source: MDDI - August 1, 2019 Category: Medical Devices Authors: Amanda Pedersen Tags: Business Source Type: news