Janssen Submits New Drug Application to U.S. FDA for XARELTO ® (rivaroxaban) to Help Prevent and Treat Blood Clots in Pediatric Patients
RARITAN, NJ, June 23, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today it has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for the use of XARELTO® (rivaroxaban) in pediatric patients. The NDA seeks two pediatric indications: treatment of venous thromboembolism (VTE, or blood clots) and reduction in the risk of recurrent VTE in patients aged birth to less than 18 years of age after at least five days of initial parenteral anticoagulant treatment; and thromboprophylaxis (prevention of blood clots) in patients aged 2 years and older with co...
Source: Johnson and Johnson - June 23, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Spirituality can promote the health of breast cancer survivors
(University of Missouri-Columbia) MU study finds link between forgiveness, congregational support and neuroimmune biomarkers. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 23, 2021 Category: International Medicine & Public Health Source Type: news

Robots may soon be able to reproduce - will this change how we think about evolution? | Emma Hart
Nature is full of examples of biology adapting to its surroundings. Technology may just be about to catch upFrom the bottom of the oceans to the skies above us, natural evolution has filled our planet with a vast and diverse array of lifeforms, with approximately 8 million species adapted to their surroundings in a myriad of ways. Yet 100 years after Karel Čapekcoined the termrobot, the functional abilities of many species still surpass the capabilities of current human engineering, which has yet to convincingly develop methods of producing robots that demonstrate human-level intelligence, move and operate seamlessly in c...
Source: Guardian Unlimited Science - June 21, 2021 Category: Science Authors: Emma Hart Tags: Robots Artificial intelligence (AI) Technology UK news Computing Consciousness Science Human biology Neuroscience Psychology World news Source Type: news

Surgical treatment of brain tumors should also be considered for the elderly
(University of Helsinki) A Finnish study indicates that neurosurgical treatment of benign brain tumors improves the quality of life of elderly people in good health and adds to their lifespan. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 21, 2021 Category: International Medicine & Public Health Source Type: news

Mechanical engineer receives NSF CAREER award to pioneer robot-assisted rehabilitation
(Northern Arizona University) Zach Lerner, an assistant professor in Northern Arizona University's Department of Mechanical Engineering, was recently awarded a $538,563 grant from the National Science Foundation (NSF) to build on his research into restoring neuromuscular function and augmenting human ability through the design, control and testing of robotic exoskeletons. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 21, 2021 Category: International Medicine & Public Health Source Type: news

Memory helps us evaluate situations on the fly, not just recall the past
(Northwestern University) Scientists have long known the brain's hippocampus is crucial for long-term memory. Now a new Northwestern Medicine study has found the hippocampus also plays a role in short-term memory and helps guide decision-making. The findings shed light on how the hippocampus contributes to memory and exploration, potentially leading to therapies that restore hippocampal function, which is impacted in memory-related aging and neurodegenerative diseases such as dementia, the study authors said. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 18, 2021 Category: International Medicine & Public Health Source Type: news

Blavatnik National Awards for Young Scientists announces the finalists of 2021
(New York Academy of Sciences) The Blavatnik National Awards today named 31 finalists for the world's largest unrestricted prize honoring early-career scientists. The finalists were culled from 298 nominations by 157 U.S. research institutions across 38 states. They have made trailblazing discoveries in wide-ranging fields, from the neuroscience of addiction to the development of gene-editing technologies, from designing next-generation battery storage to understanding the origins of photosynthesis, from making improvements in computer vision to pioneering new frontiers in polymer chemistry. (Source: EurekAlert! - Social a...
Source: EurekAlert! - Social and Behavioral Science - June 15, 2021 Category: International Medicine & Public Health Source Type: news

How depression affects the brain
New research on the neurobiology of depression is leading to a fuller understanding of the brain and the potential for new treatments of the disease. (Source: Yale Science and Health News)
Source: Yale Science and Health News - June 14, 2021 Category: Universities & Medical Training Source Type: news

Brain capillary structures show a correlation with their neuron structures
(Tokyo Metropolitan Institute of Medical Science) We analyzed cerebral tissues of the anterior cingulate cortex and superior temporal gyrus of schizophrenia cases and controls by using micro-CT. Mean curvatures of the capillary vessels showed a significant correlation to the mean curvatures of neurites, while the mean capillary diameter was almost constant, independent of the cases. The curved capillaries with a constant diameter should occupy a nearly constant volume, while neurons suffering from neurite thinning should have reduced volumes in schizophrenia (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 13, 2021 Category: International Medicine & Public Health Source Type: news

David Eagleman: ‘The working of the brain resembles drug dealers in Albuquerque’
The neuroscientist, broadcaster and author on the evolution of the brain, the mystery of consciousnesss, and why the next generation will be much smarter than usDavid Eagleman, 50, is an American neuroscientist, bestselling author and presenter of the BBC seriesThe Brain, as well as co-founder and chief executive officer of Neosensory, which develops devices for sensory substitution. His area of speciality is brain plasticity, and that is the subject of his new book,Livewired, which examines how experience refashions the brain, and shows that it is a much more adaptable organ than previously thought.For the past half-centu...
Source: Guardian Unlimited Science - June 13, 2021 Category: Science Authors: Andrew Anthony Tags: Neuroscience Medical research Books Elon Musk Technology Culture Science and nature books Source Type: news

New Phase 3 Study Results Show IMBRUVICA ® (ibrutinib)-Based Combination Regimen as an All-Oral Fixed-Duration Treatment Demonstrated Superior Progression-Free Survival in Adult Patients with Previously Untreated Chronic Lymphocytic Leukemia
Raritan, N.J., June 12, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced primary results from the pivotal Phase 3 GLOW study (NCT03462719) evaluating fixed-duration IMBRUVICA® plus venetoclax (I+V) compared to chlorambucil plus obinutuzumab (Clb+O) for first-line treatment of elderly or unfit patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). The study demonstrated superior progression-free survival (PFS) of a once-daily, all-oral, fixed-duration regimen of I+V versus Clb+O as first-line treatment of CLL; the study also showed improved duratio...
Source: Johnson and Johnson - June 12, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Janssen Announces Results from Phase 3 MAIA Study Showing Significant Overall Survival Benefits for Treatment with DARZALEX ® (daratumumab) in Patients with Newly Diagnosed Multiple Myeloma Who are Transplant Ineligible
Raritan, N.J., June 12, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced overall survival (OS) results from the Phase 3 MAIA (NCT02252172) study showing the addition of DARZALEX® (daratumumab) to lenalidomide and dexamethasone (D-Rd) resulted in a statistically significant survival benefit over lenalidomide and dexamethasone (Rd) alone in patients with newly diagnosed multiple myeloma (NDMM) who were ineligible for autologous stem cell transplant (ASCT) and were treated to progression.[1] These data were featured in the European Hematology Association (EHA) 2021 Virtual Press Briefin...
Source: Johnson and Johnson - June 12, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

The Controversy Over the FDA ’s Approval of The First Alzheimer’s Treatment Keeps Growing
“The whole thing is befuddling, and a series of inexplicable surprises,” says Dr. Caleb Alexander, professor of epidemiology and medicine at the Johns Hopkins Bloomberg School of Public Health. Alexander is a member of the U.S. Food and Drug Administration’s advisory committee that provided recommendations to the agency on whether or not to approve the Alzheimer’s drug aducanumab. On June 7, the FDA did approve the drug (under the brand name Aduhelm), in a highly controversial decision that continues to divide the Alzheimer’s community. Patients and advocacy groups, including the Alzheimer&rsq...
Source: TIME: Health - June 11, 2021 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized Source Type: news

Scientists link intense exercise with MND risk in some people
Those with a certain genetic makeup more likely to develop motor neurone disease, study confirmsRegular strenuous exercise raises the risk of developing motor neurone disease (MND) in people who are genetically predisposed to the condition, researchers say.Scientists at the University of Sheffield found a causal relationship between high intensity physical activity and the disorder among those already susceptible to the disease.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - June 11, 2021 Category: Science Authors: Ian Sample Science editor Tags: Medical research Motor neurone disease Science Health University of Sheffield Education Source Type: news

New program brings Meharry Medical students into the ‘Yale family’
Yale's summer research partnership with the historically Black medical school offers one-on-one experience in psychiatry, neurosurgery, and neuroscience. (Source: Yale Science and Health News)
Source: Yale Science and Health News - June 10, 2021 Category: Universities & Medical Training Source Type: news

Scientific Breakthroughs with Cryogenic Electron Microscopy
Structures made via cryo-EM give researchers insights into SARS-CoV-2, HIV, neurological disorders, cancer, and more. (Source: The Scientist)
Source: The Scientist - June 10, 2021 Category: Science Tags: Sponsored Infographics Source Type: news

'Roadmaps' of the brain reveal regions vulnerable to Alzheimer's disease
(Van Andel Research Institute) Much like a supply truck crossing the countryside, the misfolded proteins that damage neurons in Alzheimer's disease travel the " roads " of the brain, sometimes stopping and sometimes re-routing to avoid roadblocks, reports a study published in Science Advances by researchers at Van Andel Institute and University of Pennsylvania. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 10, 2021 Category: International Medicine & Public Health Source Type: news

Like night and day: Animal studies may not translate to humans without time considerations
(West Virginia University) Randy Nelson -- chair of the WVU Department of Neuroscience and director of basic science research for the Rockefeller Neuroscience Institute -- and his colleagues reviewed some of the most frequently cited neuroscience studies and determined most didn't take time of day into account. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 10, 2021 Category: International Medicine & Public Health Source Type: news

Winner Art of Neuroscience competition announced
(Netherlands Institute for Neuroscience - KNAW) The eleventh edition of the Art of Neuroscience competition is won by Yas Crawford, an associate of the Royal Photographic Society and independent artist. With her artwork 'Cognition IX', Crawford looks at neurological interoception in myalgic encephalomyelitis (M.E) patients. The winner was chosen by a jury out of 293 entries from over 20 countries. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 10, 2021 Category: International Medicine & Public Health Source Type: news

Moral disgust has a 'bad taste'
(Universit à di Bologna) Witnessing shared moral norms being disrespected inhibits the neurons responsible for controlling our tongue, a reaction similar to the one we have when we taste something unpleasant. This is what emerges from a study led by the University of Bologna and the University of Messina. This work received the " Best Paper Prize 2021 " during the XII International Scientific Conference on Neuroethics. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 10, 2021 Category: International Medicine & Public Health Source Type: news

Cloud computing expands brain sciences
(University of Texas at Austin, Texas Advanced Computing Center) Leading neuroscientist collaborates with TACC to democratize the field, support infrastructure. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 10, 2021 Category: International Medicine & Public Health Source Type: news

What happens in the brain when people make music together?
(Bar-Ilan University) Inspired by people around the world who made music together while social distancing during the COVID-19 pandemic, researchers from Bar-Ilan University and the University of Chicago fused the latest advances in social neuroscience and the field of music to highlight five key functions and mechanisms of the brain that contribute to social connection through music. The findings illustrate that music isn't just mere entertainment, but a core feature of human existence with important social implications. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 10, 2021 Category: International Medicine & Public Health Source Type: news

Common mechanism found for diverse brain disorders: Study
(Vanderbilt University Medical Center) Researchers at Vanderbilt University Medical Center (VUMC) have identified a common mechanism underlying a spectrum of epilepsy syndromes and neurodevelopmental disorders, including autism, that are caused by variations in a gene encoding a vital transporter protein in the brain. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 9, 2021 Category: International Medicine & Public Health Source Type: news

How do we know we ’re not living in a simulation like The Matrix?
The long-running series in which readers answer other readers ’ questions on subjects ranging from trivial flights of fancy to profound scientific and philosophical conceptsHow do we know we ’re not living in a simulation like The Matrix?Jack Freedom, BristolPost your answers (and new questions) below or send them tonq@theguardian.com. A selection will be published on Sunday.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - June 8, 2021 Category: Science Tags: Psychology Science Life and style Neuroscience Philosophy The Matrix Source Type: news

Changing the way we do science
(McGill University) Today The Neuro (Montreal Neurological Institute-Hospital) is launching the Clinical Biospecimen Imaging and Genetic (C-BIG) Repository, one of the largest biorepositories of neurological disorders in the world, as an open access resource for the global scientific community. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 8, 2021 Category: International Medicine & Public Health Source Type: news

Weak brain waves may warn of age-related neurodegenerative disease
(eLife) Weakened electrical signals in the brain may be an early warning sign of age-related neurodegenerative diseases such as Alzheimer's disease. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 8, 2021 Category: International Medicine & Public Health Source Type: news

The First Treatment for Alzheimer ’s Disease Is Here
Alzheimer’s disease was first described by Alois Alzheimer in 1906, and now, more than 100 years later, doctors have an effective drug to treat the cognitive disorder. On June 7, the U.S. Food and Drug Administration (FDA) approved aducanumab, developed by the U.S.-based biotech Biogen and Japanese pharmaceutical company Eisai. But the drug’s approval comes with a caveat. The FDA is requiring Biogen to conduct an additional placebo controlled study of the drug to verify it’s effectiveness in improving people’s memory and cognitive symptoms. That request stems in large part from the conclusion of an ...
Source: TIME: Health - June 7, 2021 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized Source Type: news

Correcting misperceptions about, and increasing empathy for, migrants
(University of Pennsylvania) A new study from the Peace and Conflict Neuroscience Lab at the Annenberg School for Communication found that Americans dramatically overestimate the number of migrants affiliated with gangs and children being trafficked, and that this overestimation contributes to dehumanization of migrants, lack of empathy for their suffering, and individuals' views on immigration policy. In addition, the researchers developed and tested interventions to address this misinformation and increase empathy for undocumented immigrants. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 7, 2021 Category: International Medicine & Public Health Source Type: news

Researchers identify a molecule critical to functional brain rejuvenation
(Advanced Science Research Center, GC/CUNY) A new study from a CUNY ASRC Neuroscience Initiative team has identified a molecule called ten-eleven-translocation 1 (TET1) as a necessary component in the repair of myelin, which protects nerves and facilitates accurate transmission of electrical signals. The discovery could have important implications in treating neurodegenerative diseases and for molecular rejuvenation of aging brains in healthy individuals. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 7, 2021 Category: International Medicine & Public Health Source Type: news

Simple blood test can accurately reveal underlying neurodegeneration
(King's College London) A new study of over 3000 people led by King's College London in collaboration with Lund University, has shown for the first time that a single biomarker can accurately indicate the presence of underlying neurodegeneration in people with cognitive issues. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 7, 2021 Category: International Medicine & Public Health Source Type: news

Your Weirdest Dreams Could Be Making You Smarter Your Weirdest Dreams Could Be Making You Smarter
The unusual sights and sounds we experience in our dreams might not be random, and could play a role in the way we learn, according to new scientific findings.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - June 4, 2021 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Infographic: Reverse Signaling Between Neurons
So-called mossy fiber synapses in the hippocampus can meter the amount of neurotransmitter they receive by sending glutamate against the usual direction of synaptic flow. (Source: The Scientist)
Source: The Scientist - June 4, 2021 Category: Science Tags: Infographics Source Type: news

Hippocampal Cell Communication Is Bidirectional: Study
In an unexpected twist in neuroscience dogma, the cells on the receiving end of neurotransmission appear to be able to release glutamate to regulate the transmitting cell's activity. (Source: The Scientist)
Source: The Scientist - June 4, 2021 Category: Science Tags: News & Opinion Source Type: news

Neuromics' Renal Proximal Tubule Cells in Action
In this study, ourRPT Cells were used to study the impact of Klothko expression on protection of kidneys in diabetics: Meng Xue, Feng Yang, Ying Le, Yanlin Yang, Bingsen Wang, Yijie Jia, Zongji Zheng, and Yaoming Xue. (2021).Klotho Protects Against Diabetic Kidney Disease via AMPK- and ERK-Mediated Autophagy. Acta Diabetologica, 32. doi: 10.1007/s00592-021-01736-4.Klotho expression in human renal proximal tubule cells after high-glucose stimulation. (a) Levels of Klotho mRNA and (b) Klotho protein were assessed in human renal proximal tubule cells treated with low glucose and high glu- cose. (c) Morphological observat...
Source: Neuromics - June 3, 2021 Category: Neuroscience Source Type: news

Army leverages virtual reality to understand network influence
(U.S. Army Research Laboratory) The US Army Combat Capabilities Development Command, known as DEVCOM, Army Research Laboratory funded scientists at Kent State University's Electrophysiological Neuroscience Laboratory to create an immersive virtual reality lab that can be used in tandem with their other biophysiological technologies to advance an interdisciplinary understanding of group dynamics. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 3, 2021 Category: International Medicine & Public Health Source Type: news

New Phase 3b Psoriatic Arthritis (PsA) Data Show First-in-Class TREMFYA ® (guselkumab) Achieved Robust Joint Symptom Improvement and Complete Skin Clearance in Patients with Inadequate Response to Tumor Necrosis Factor Inhibition (TNFi-IR)
SPRING HOUSE, PENNSYLVANIA, June 2, 2021 – Today the Janssen Pharmaceutical Companies of Johnson & Johnson announced new efficacy and safety data for first-in-class TREMFYA® (guselkumab), including data from the first study evaluating a selective IL-23 inhibitor in adult patients with active PsA, all of whom had demonstrated inadequate response or intolerance to TNFi.1 In the COSMOS Phase 3b study, significantly higher proportions of patients treated with TREMFYA showed joint symptom improvement and complete skin clearance versus placebo at week 24 in this true TNFi-IRa patient population, which is often more...
Source: Johnson and Johnson - June 2, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Scientific Meeting » Neurologic and Psychiatric Effects of SARS-CoV-2 Meeting
The NIMH, National Institute of Neurological Disorders and Stroke, and National Institute on Aging are conducting a virtual meeting on the neurologic and psychiatric effects of SARS-CoV-2 infection from July 14-15, 2021. (Source: National Institute of Mental Health)
Source: National Institute of Mental Health - June 2, 2021 Category: Psychiatry Authors: National Institute of Mental Health Source Type: news

Janssen Highlights Commitment to Advancing Transformative Innovations in Oncology with Scientific Updates from Deep, Diverse Pipeline and Portfolio at ASCO and EHA Virtual Scientific Programs
June 1, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that more than 30 company-sponsored studies, including six oral presentations, will be featured during the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting, June 4-8. Janssen presentations will include new data and updates for both approved and investigational therapeutics that are being studied for the treatment of various solid tumors and blood cancers. Immediately following ASCO, additional data will be featured during the European Hematology Association (EHA) Virtual Congress, June 9-17. A ...
Source: Johnson and Johnson - June 1, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Janssen Announces U.S. FDA Breakthrough Therapy Designation Granted for Teclistamab for the Treatment of Relapsed or Refractory Multiple Myeloma
June 1, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy Designation (BTD) for teclistamab in the treatment of relapsed or refractory multiple myeloma. This distinction for teclistamab, an off-the-shelf, T-cell redirecting, bispecific antibody targeting both B-cell maturation antigen (BCMA) and CD3 receptors, follows a PRIME (PRIority MEdicines) designation from the European Medicines Agency (EMA) received earlier this year. Today’s BTD marks the 11th received by Janssen’s ...
Source: Johnson and Johnson - June 1, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Janssen Reports New Data for BCMA CAR-T, Cilta-Cel, Showing Deep and Durable Responses in Patients with Relapsed or Refractory Multiple Myeloma
June 1, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new data for ciltacabtagene autoleucel (cilta-cel), an investigational B-cell maturation antigen (BCMA)-directed CAR-T therapy, demonstrated sustained efficacy and durable responses in heavily pretreated patients with relapsed/refractory multiple myeloma (RRMM). Updated results from the Phase 1b/2 CARTITUDE-1 study (n=97) with a longer-term follow-up at a median of 18 months showed an overall response rate (ORR) of 98 percent, with 80 percent of patients achieving a stringent complete response (sCR), highlight...
Source: Johnson and Johnson - June 1, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Opinion: The Overlooked Power of Inhibitory Neurons
Understanding how the brain coordinates electrical activity could be key to developing more-effective treatments for a variety of brain disorders. (Source: The Scientist)
Source: The Scientist - June 1, 2021 Category: Science Tags: Reading Frames Magazine Issue Source Type: news

Why moms take risks to protect their infants
(RIKEN) It might seem like a given than mothers take extra risks to protect their children, but have you ever wondered why? A new study led by Kumi Kuroda at the RIKEN Center for Brain Science (CBS) in Japan shows that in mice, this and other nurturing behaviors are driven in part by neurons in a small part of the forebrain that contain a protein called the calcitonin receptor. The study was published in Cell Reports. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 1, 2021 Category: International Medicine & Public Health Source Type: news

Protecting the intellectual abilities of people at risk for psychosis
(Universit é de Gen è ve) Psychotic disorders comes with a progressive decline in IQ. If current drug treatments are successful in containing psychotic symptoms, nothing can be done to prevent the deterioration of intellectual skills that leads to loss of autonomy. Researchers (UNIGE) have discovered that prescription of selective serotonin reuptake inhibitors (SSRIs) in late childhood can reduce the deterioration of intellectual abilities and have a neuroprotective effect on some of the brain regions affected by the psychotic illness. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 1, 2021 Category: International Medicine & Public Health Source Type: news

Brain activity reveals when white lies are selfish
(Society for Neuroscience) You may think a little white lie about a bad haircut is strictly for your friend's benefit, but your brain activity says otherwise. Distinct activity patterns in the prefrontal cortex reveal when a white lie has selfish motives, according to new research published in JNeurosci. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - May 31, 2021 Category: International Medicine & Public Health Source Type: news

Science Saturday: How regenerative medicine is advancing ALS research
May is?ALS Awareness Month, a time to reflect on the role of regenerative medicine research in advancing understanding and treatment of amyotrophic lateral sclerosis?(ALS) or Lou Gehrig's disease. This neurodegenerative disorder causes nerve cells in the brain and spinal cord to die, blocking signals to the muscles. That results in paralysis that robs a person [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - May 29, 2021 Category: Databases & Libraries Source Type: news

IRRAS Announces publication of a Case report from Buffalo General Medical Center, highlights clinical superiority of IRRAflow treatment versus traditional drainage
IRRAflow Intraventricular Hemorrhage (IVH) Case Report Published in Cureus Journal of Medical Science Publication also documents the ability to deliver targeted thrombolytic medication via IRRAflow's recurring irrigation for the first time in peer-revie... Devices, Neurosurgery, Monitoring IRRAS, IRRAflow, Hummingbird, ICP Monitor (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - May 28, 2021 Category: Pharmaceuticals Source Type: news

Trigeminal Neuralgia (Facial Pain)
 Markers for Pain ResearchTrigeminal Neuralgia is a progress chronic condition. Dysfunctional trigeminal signaling can lead to intense, searing facial pain. It is caused by pressure on the trigeminal nerve.The root causes of the condition are not well understood. Ourpain research markers have been widely used and frequently published through the years and have been important contributors to our growth, Here's a recent pub referencing use of one ourP2X3 Antibodies-Momoko Koizumi, Sayaka Asano, Akihiko Furukawa, Yoshinori Hayashi, Suzuro Hitomi, Ikuko Shibuta, Katsuhiko Hayashi, Fusao Kato, Koichi Iwata, and Masamichi S...
Source: Neuromics - May 27, 2021 Category: Neuroscience Tags: Craniofacial pain P2X3 Antibody P2X3 Receptor Antibody Trigeminal Neurons Source Type: news

Updated Data Demonstrate Significant Improvement in Hematologic Complete Response with DARZALEX FASPRO ® (daratumumab and hyaluronidase-fihj) in Patients with Newly Diagnosed Light Chain (AL) Amyloidosis
RARITAN, N.J., May 26, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced updated results from the Phase 3 ANDROMEDA study, which evaluated DARZALEX FASPRO® (daratumumab and hyaluronidase-fihj) for the treatment of patients with newly diagnosed light chain (AL) amyloidosis, a rare blood cell disorder associated with the deterioration of vital organs, most notably the heart, kidneys and liver.[1] Longer-term results from a median follow-up of 20.3 months showed rates of hematologic complete response (hemCR) remained significantly higher in patients treated with DARZALEX FASPRO®...
Source: Johnson and Johnson - May 26, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Long-Term ERLEADA ® (apalutamide) Patient-Reported Outcomes Data in Metastatic Castration-Sensitive Prostate Cancer Demonstrate Maintenance of Health-Related Quality of Life for Patients
May 26, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced patient-reported outcomes (PRO) data from the pre-specified final analysis of the Phase 3 TITAN study in patients with metastatic castration-sensitive prostate cancer (mCSPC). The TITAN study previously demonstrated statistically significant improvement in overall survival (OS) after a median follow-up of 44 months in patients receiving ERLEADA® plus androgen deprivation therapy (ADT).1 The new PRO data showed that the addition of ERLEADA® to ADT maintained patients’ health-related quality of lif...
Source: Johnson and Johnson - May 26, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Novel approaches in treating neurodegenerative disorders
(Bentham Science Publishers) This book presents distinct advanced treatment alternatives for Neurodegenerative diseases that will be of significant interest for scientists and researchers working in this field. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 26, 2021 Category: International Medicine & Public Health Source Type: news