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By using antisense oligonucleotides to inhibit a mutated exon associated with Timothy syndrome mutation, researchers restored neuron function. (Source: The Scientist)
Source: The Scientist - April 26, 2024 Category: Science Tags: News News & Opinion Source Type: news
UCLA Grad Slam winner sheds light on cerebellum ’s role in autism
Key takeawaysThe annual Grad Slam competition challenges graduate students to briefly explain their research in a clear and accessible way in front of an audience of non-experts.This year ’s winner, neuroscience doctoral candidate Melis Çakar, spoke about how activity in a brain structure called the cerebellum correlates with over-responsivity to sensory stimuli in people with autism spectrum disorder.Çakar beat out 52 other competitors and won $5,000; she will now represent UCLA at the UC-wide Grad Slam competition on May 3.Imagine you ’re trying to catch a ball or tie your shoes. It is your cerebellum, a part of y...
Source: UCLA Newsroom: Health Sciences - April 25, 2024 Category: Universities & Medical Training Source Type: news
Glia are powerhouses for sleep | Science Signaling
Glia take up and detoxify neurotoxic lipids on a wake-sleep cycle, in turn promoting healthy sleep. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - April 23, 2024 Category: Science Source Type: news
Soiled nappies and karate: AI-rendered Putin biopic to be released
Polish director Besaleel ’s film will feature an AI-rendered Russian president and footage shot by Ukrainian film-makers during the Russian invasionThe “world premiere” of a new biopic of Russian president Vladimir Putin featuring an AI-rendered central character, has been announced for 26 September.In a statement released via PR Leap, Polish studio AIO said the film, titled Putin, will be released in 35 countries, and describes itself as “up close and personal with the Kremlin leader’s story”.First announced in May 2022, Putin is the English-language debut of Polish director Besaleel, also known as Patryk Vega...
Source: Guardian Unlimited Science - April 23, 2024 Category: Science Authors: Andrew Pulver Tags: Film Vladimir Putin Artificial intelligence (AI) Poland Ukraine Computing Consciousness Culture Europe Human biology Neuroscience Psychology Technology World news Biopics Source Type: news
‘Like a film in my mind’: hyperphantasia and the quest to understand vivid imaginations
Research that aims to explain why some people experience intense visual imagery could lead to a better understanding of creativity and some mental disordersWilliam Blake ’s imagination is thought to have burned with such intensity that, when creating his great artworks, he needed little reference to the physical world. While drawing historical or mythical figures, for instance, he would wait until the “spirit” appeared in his mind’s eye. The visions were app arently so detailed that Blake could sketch as if a real person were sitting before him.Like human models, these imaginary figures could sometimes act temperam...
Source: Guardian Unlimited Science - April 20, 2024 Category: Science Authors: David Robson Tags: Psychology Neuroscience Neurodiversity Society Source Type: news
Workshop: Neurofeedback Intervention Development: Opportunities and Challenges
This workshop will convene researchers and federal officials to review the state of the science for neurofeedback intervention development for mental disorders, with an emphasis on real time fMRI approaches. (Source: National Institute of Mental Health)
Source: National Institute of Mental Health - April 19, 2024 Category: Psychiatry Authors: National Institute of Mental Health Source Type: news
Experts warn GPs on prescribing antipsychotic drugs for dementia
Use of powerful medications linked to elevated risk of serious adverse outcomes including heart failureDoctors are being urged to reduce prescribing of antipsychotic drugs to dementia patients after the largest study of its kind found they were linked to more harmful side-effects than previously thought.The powerful medications are widely prescribed for behavioural and psychological symptoms of dementia such as apathy, depression, aggression, anxiety, irritability, delirium and psychosis. Tens of thousands of dementia patients in England are prescribed them every year.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - April 17, 2024 Category: Science Authors: Andrew Gregory Health editor Tags: Dementia Mental health Society Neuroscience Medical research Older people England UK news GPs Doctors NHS Source Type: news
Dementia: experts urge doctors to reduce antipsychotic prescriptions
Use of powerful medications linked to elevated risk of serious adverse outcomes including heart failureDoctors are being urged to reduce prescribing of antipsychotic drugs to dementia patients after the largest study of its kind found they were linked to more harmful side-effects than previously thought.The powerful medications are widely prescribed for behavioural and psychological symptoms of dementia such as apathy, depression, aggression, anxiety, irritability, delirium and psychosis. Tens of thousands of dementia patients in England are prescribed them every year.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - April 17, 2024 Category: Science Authors: Andrew Gregory Health editor Tags: Dementia Mental health Society Neuroscience Medical research Older people England UK news GPs Doctors NHS Source Type: news
Roche ’s subcutaneous OCREVUS one-year data demonstrates near-complete suppression of clinical relapses and brain lesions in patients with progressive and relapsing forms of MS
Results from the Phase III study showed that subcutaneous (SC) injection was consistent with IV infusion and demonstrated near-complete suppression of relapse activity (97%) and MRI lesions (97.2%) through 48 weeksThe twice-yearly, 10-minute SC injection has the potential to expand the usage of OCREVUS to treatment centres without IV infrastructure or with IV capacity limitationsU.S. FDA and EMA accepted filings based on the data from OCARINA II, with EU approval anticipated mid-2024 and U.S. approval anticipated September 2024Basel, 17 April 2024 - Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today data from the Phase III...
Source: Roche Media News - April 17, 2024 Category: Pharmaceuticals Source Type: news
Here's how the brain experiences pleasure — even the kind that makes us feel guilty
We've all been there: You sit down for one episode of a reality TV show, and six hours later you're sitting guiltily on the couch, blinking the screen-induced crust off your eyeballs. Okay. Maybe you haven't been there like our team has. But it's likely you have at least one guilty pleasure, whether it's playing video games, reading romance novels or getting swept into obscure corners of TikTok. It turns out that experiencing – and studying – pleasure is not as straightforward as it might seem. And yet, pleasure is quite literally key to the survival of humanity. So today on the show, we explore the pleasure cycle: Wha...
Source: NPR Health and Science - April 15, 2024 Category: Consumer Health News Authors: Emily Kwong Source Type: news
Your brain on genetics
There ’s nothing like seeing new perspectives through the study of neurodegenerative and neuropsychiatric diseases.Dr. Daniel Geschwind— without getting too philosophical, he promises — is ready to explain why.Geschwind, the Gordon and Virginia MacDonald Distinguished Professor of Human Genetics, Neurology and Psychiatry at UCLA, has been a pioneering neurogeneticist for more than 25 years, during which time a genomics revolution has allowed research, much of which has come out of UCLA, to show that psychiatric disorders have pathology that ties t hem together.In the last 10 years, hundreds of genes that increase s...
Source: UCLA Newsroom: Health Sciences - April 11, 2024 Category: Universities & Medical Training Source Type: news
Long Covid trials aim to clear lingering virus —and help patients in need
One Monday morning last September, Shelley Hayden pulled into a parking spot in an underground garage at the University of California San Francisco (UCSF). She switched off the ignition, pushed the red record button on her cellphone, and gazed into the camera. “The time has come,” said Hayden, long dark-blond hair framing her blue eyes. “Here we are, I’m actually getting to do something.”
More than 3 years earlier, in the summer of 2020, Hayden had come down with COVID-19 while visiting family in Colorado. Since then she’s been plagued by the disease’s cruel sequel, Long Covid, whose symptoms include ov...
Source: ScienceNOW - April 11, 2024 Category: Science Source Type: news
Roche granted FDA Breakthrough Device Designation for blood test to support earlier Alzheimer's disease diagnosis
The Elecsys ® pTau217 plasma biomarker test is being developed as part of an ongoing partnership between Roche and Eli Lilly and CompanyOnce approved, the test will aid healthcare providers in identifying amyloid pathology, a key feature of Alzheimer ’s diseaseRoche and Lilly believe the test could play an important role in improving access to early and accurate Alzheimer ’s diagnosisBasel, 11 April 2024 - Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that its Elecsys pTau217 assay received Breakthrough Device Designation from the U.S. Food and Drug Administration (FDA). This blood test, which is being developed ...
Source: Roche Investor Update - April 11, 2024 Category: Pharmaceuticals Source Type: news
Roche granted FDA Breakthrough Device Designation for blood test to support earlier Alzheimer's disease diagnosis
The Elecsys ® pTau217 plasma biomarker test is being developed as part of an ongoing partnership between Roche and Eli Lilly and CompanyOnce approved, the test will aid healthcare providers in identifying amyloid pathology, a key feature of Alzheimer ’s diseaseRoche and Lilly believe the test could play an important role in improving access to early and accurate Alzheimer ’s diagnosisBasel, 11 April 2024 - Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that its Elecsys pTau217 assay received Breakthrough Device Designation from the U.S. Food and Drug Administration (FDA). This blood test, which is being developed ...
Source: Roche Media News - April 11, 2024 Category: Pharmaceuticals Source Type: news
UCLA receives $5 million grant to align neuroscience and societal needs
The objective is to reimagine the relationship between neuroscience and the public in part by deepening community engagement, facilitating research collaborations and training multidisciplinary neuro-society experts.Led by the David Geffen School of Medicine at UCLA, numerous campus units and Drew University are together contributing about $4.8 million to match the grant amount. They include theBrain Research Institute; theSemel Institute for Neuroscience and Human Behavior; the UCLA College divisions of life sciences, social sciences and humanities; the School of Education& Information Studies; and the Office of the...
Source: UCLA Newsroom: Health Sciences - April 10, 2024 Category: Universities & Medical Training Source Type: news
