Alpha-pine self-emulsifying nano formulation attenuates rotenone and trichloroethylene-induced dopaminergic loss
. (Source: International Journal of Neuroscience)
Source: International Journal of Neuroscience - April 24, 2024 Category: Neuroscience Authors: Rajnish SrivastavaPratim Kumar ChoudhurySuresh Kumar DevVaibhav Rathorea Chitkara University School of Pharmacy, Chitkara University, Himachal Pradesh, Indiab Department of Pharmacy, Pacific Academy of Higher Education and Research University, Rajasthan, Source Type: research

Clinical course and predictors of outcome following surgical treatment of benign peripheral nerve sheath tumors, a single center retrospective study
. (Source: International Journal of Neuroscience)
Source: International Journal of Neuroscience - April 24, 2024 Category: Neuroscience Authors: Erik ÖhlénVictor Gabriel El-HajjAlexander Fletcher-SandersjööErik EdströmAdrian Elmi-Terandera Department of Pediatrics, Mälar Hospital, Eskilstuna, Swedenb Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Swedenc Capio Spine C Source Type: research

Comparative analysis of low-dose bupivacaine and ropivacaine combined with spinal-epidural anesthesia in cesarean sections for pregnant women with coexisting mental illness
. (Source: International Journal of Neuroscience)
Source: International Journal of Neuroscience - April 24, 2024 Category: Neuroscience Authors: Qiurong MiYi Zhaoa Department of Anesthesiology, Children ’s Hospital of Shanxi (Women Health Center of Shanxi), Taiyuan, Chinab Department of Affective Disorders, Taiyuan Mental Hospital, Taiyuan, China Source Type: research

Exploration of the impact of dysbiosis in the gut microbiota on microbial composition in children ’s neurodevelopment
. (Source: International Journal of Neuroscience)
Source: International Journal of Neuroscience - April 24, 2024 Category: Neuroscience Authors: Ting GuoZhenzhong ZengLiangfeng LinDepartment of Pediatrics, the Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, China Source Type: research

Effects of mini-basketball training program on social communication impairments and regional homogeneity of brain functions in preschool children with autism spectrum disorder
ConclusionsOur study underscores the effectiveness of a 12-week MBTP in ameliorating SCI and abnormalities in ReHo among preschool children with ASD.Trial registrationThe trial is retrospectively registered on the Chinese Clinical Trial Registry (ChiCTR1900024973; August 5, 2019). (Source: BMC Sports Science, Medicine and Rehabilitation)
Source: BMC Sports Science, Medicine and Rehabilitation - April 24, 2024 Category: Sports Medicine Source Type: research

"Pressure kills kidneys": protection of the upper urinary tract through neuro-urological management
This article is intended to provide information about the epidemiology and complex pathogenetic mechanisms as well as the necessary diagnostic steps. Various medical, interventional and surgical treatment strategies are evaluated on the basis of current scientific findings, thus supporting the reader in the care of this complex patient group.PMID:38653468 | DOI:10.1055/a-2287-4933 (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - April 23, 2024 Category: Urology & Nephrology Authors: Fabian Quei ßert Andres Jan Schrader Source Type: research

Cingulotomy for Intractable Pain: A Systematic Review of an Underutilized Procedure
Cureus. 2024 Mar 22;16(3):e56746. doi: 10.7759/cureus.56746. eCollection 2024 Mar.ABSTRACTPain management is a critical aspect of cancer treatment and palliative care, where pain can significantly impact quality of life. Chronic pain, which affects a significant number of people worldwide, remains a prevalent and challenging symptom for patients. While medications and psychosocial support systems play a role in pain management, surgical and radiological interventions, including cingulotomy, may be necessary for refractory cases. Cingulotomy, a neurosurgical procedure targeting the cingulate gyrus, aims to disrupt neural pa...
Source: Cancer Control - April 23, 2024 Category: Cancer & Oncology Authors: Billy McBenedict Wilhelmina N Hauwanga Mariana P Pires Jos é Geraldo M Netto Dulci Petrus Jumana A Kanchwala Rhea Joshi Shaista Rizwan Ahamed Alurkar Otari Chankseliani Zaeemah Mansoor Sona Subash Berley Alphonse Ana Abrah ão Bruno Lima Pess ôa Source Type: research

Current Status and Associated Factors of Post-Hemorrhagic Hydrocephalus in Infants of 22 to 28 Weeks Gestation With Severe Intraventricular Hemorrhage in Korea: A Nationwide Cohort Study
CONCLUSION: It is necessary to maintain meticulous monitoring and neurological intervention for infants with PHH not only during admission but also after discharge. In addition, identifying the clinical factors that increase the likelihood of developing PHH from severe IVH is crucial.PMID:38651224 | DOI:10.3346/jkms.2024.39.e139 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - April 23, 2024 Category: Biomedical Science Authors: Misun Yang Sumin Kim Se In Sung Yun Sil Chang Won Soon Park So Yoon Ahn Source Type: research

The complexity of extracellular vesicles: Bridging the gap between cellular communication and neuropathology
In this report, we review the roles that extracellular vesicles can play in biological processes and cellular dysfunction and pathobiology, particularly neurodegenerative diseases. We also examine the potential translational impacts of extracellular vesicles in diagnostics and therapeutic development. ER: endoplasmic reticulum; ROS: reactive oxygen species. AbstractBrain-derived extracellular vesicles (EVs) serve a prominent role in maintaining homeostasis and contributing to pathology in health and disease. This review establishes a crucial link between physiological processes leading to EV biogenesis and their impacts on...
Source: Journal of Neurochemistry - April 23, 2024 Category: Neuroscience Authors: Stephanie Tam, Darcy Wear, Christopher D. Morrone, Wai Haung Yu Tags: SYSTEMATIC REVIEW Source Type: research

Expression Patterns of miRNAs in Egyptian Children with ADHD: Clinical Study with Correlation Analysis
AbstractADHD has huge knowledge gaps concerning its etiology. MicroRNAs (miRNAs) provide promising diagnostic biomarkers of human pathophysiology and may be a novel therapeutic option. The aim was to investigate the levels of miR-34c-3p, miR-155, miR-138-1, miR-296-5p, and plasma brain-derived neurotrophic factor (BDNF) in a group of children with ADHD compared to neurotypicals and to explore correlations between these measures and some clinical data. The participants were children with ADHD in Group I (N = 41; age: 8.2 ± 2) and neurotypical ones in Group II (N = 40; age: 8.6 ± 2.5). Group I was subjected...
Source: Journal of Molecular Neuroscience - April 23, 2024 Category: Neuroscience Source Type: research

Interoceptive signals from the heart and coronary circulation in health and disease
This review considers interoceptive signalling from the heart and coronary circulation. Vagal and cardiac sympathetic afferent sensory nerve endings are distributed throughout the atria, ventricles (mainly left), and coronary artery. A small proportion of cardiac receptors attached to thick myelinated vagal afferents are tonically active during the cardiac cycle. Dependent upon location, these mechanoreceptors detect fluctuations in atrial volume and coronary arterial perfusion. Atrial volume and coronary arterial signals contribute to beat-to-beat feedback control and physiological homeostasis. (Source: Autonomic Neurosci...
Source: Autonomic Neuroscience: Basic and Clinical - April 23, 2024 Category: Neuroscience Authors: Jonathan P. Moore Tags: Review Article Source Type: research

Management of wide-neck aneurysms in 2024: how does one make the best treatment decision when there are so many good options?
A middle-aged patient walks into the office for the first time with an unruptured, medium sized, wide-neck middle cerebral artery (MCA) aneurysm incorporating both M2 origins into the aneurysm neck. What is the best management for this patient? What is the safest and most effective treatment option? How does one make the decision when there are so many good options currently available? Wide-neck aneurysms (WNAs) are defined as those with a neck width >4 mm, a dome to neck ratio <2, or both features.1 They may be ruptured or unruptured. These aneurysms are more challenging to treat and require more advanced techniques...
Source: Journal of NeuroInterventional Surgery - April 23, 2024 Category: Neurosurgery Authors: Mascitelli, J. R. Tags: Basic science Source Type: research

The characteristics of white dot syndromes following COVID-19 Vaccines: a systematic review
ConclusionWhite dot syndromes are very rare entities. Our findings highlight a possible association between COVID-19 vaccines and the occurrence of white dot syndromes. However, larger studies with good quality should be implemented to confirm these findings. (Source: International Ophthalmology)
Source: International Ophthalmology - April 23, 2024 Category: Opthalmology Source Type: research

Choroid plexus immune cell response in murine hydrocephalus induced by intraventricular hemorrhage
ConclusionThere is a marked immune cell response at the ChP in IVH involving epiplexus cells, T lymphocytes and neutrophils. The blood components iron and Prx-2 may play a role in eliciting that response. Reduction of ChP macrophages with clodronate liposomes reduced iron-induced ventriculomegaly suggesting that ChP macrophages may be a promising therapeutic target for managing IVH-induced hydrocephalus. (Source: Fluids and Barriers of the CNS)
Source: Fluids and Barriers of the CNS - April 23, 2024 Category: Neuroscience Source Type: research

A light in the darkness: sodium fluorescein-assisted peripheral nerve sheath tumors resection – a comprehensive systematic review and single-arm meta-analysis
AbstractThe treatment for peripheral nerve sheath tumors (PNSTs) is based on surgical excision and the primary goal is to improve symptoms whilst preserving neurological function. In order to improve this technique, surgeons may use sodium fluorescein (SF) to help visualize the neoplasm and, consequently, facilitate its removal. Aiming to assess the efficacy of this emerging surgical strategy, we conducted a systematic review and single-arm meta-analysis. We conducted a systematic search on thePubMed,Embase, andWeb of Science databases, following thePRISMA guidelines. Studies without outcomes of interest, case series with ...
Source: Neurosurgical Review - April 23, 2024 Category: Neurosurgery Source Type: research