Roche enters into a definitive merger agreement to acquire Carmot Therapeutics, including three clinical stage assets with best-in-class potential in obesity and diabetes
Carmot Therapeutics ’s R&D portfolio of clinical stage incretins has great potential to treat obesity, diabetes and potentially other diseases both as standalone medicines and in combination with Roche ’s in-house assetsLead asset CT-388 is a Phase-2 ready dual GLP-1/GIP agonist with best-in-class potential for the treatment of obesity and its comorbiditiesUnder the terms of the agreement, Roche will pay a purchase price of USD 2.7 billion upfront and additional milestone payments of up to USD 400 millionBasel, 4 December 2023 - Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today the entry into a definitive merger a...
Source: Roche Investor Update - December 4, 2023 Category: Pharmaceuticals Source Type: news
Roche enters into a definitive merger agreement to acquire Carmot Therapeutics, including three clinical stage assets with best-in-class potential in obesity and diabetes
Carmot Therapeutics ’s R&D portfolio of clinical stage incretins has great potential to treat obesity, diabetes and potentially other diseases both as standalone medicines and in combination with Roche ’s in-house assetsLead asset CT-388 is a Phase-2 ready dual GLP-1/GIP agonist with best-in-class potential for the treatment of obesity and its comorbiditiesUnder the terms of the agreement, Roche will pay a purchase price of USD 2.7 billion upfront and additional milestone payments of up to USD 400 millionBasel, 4 December 2023 - Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today the entry into a definitive merger a...
Source: Roche Media News - December 4, 2023 Category: Pharmaceuticals Source Type: news
A Story of FIRE and Mice
Studying how microglia control myelin growth and prevent its degeneration helps scientists better understand and address neurodegenerative diseases. (Source: The Scientist)
Source: The Scientist - December 4, 2023 Category: Science Tags: Features Magazine Issue Source Type: news
Infographic: Microglia Influence Myelin Health
In FIRE mice, the lack of microglia causes myelin overgrowth and eventual degeneration, indicating that microglia may contribute to age-related neurodegenerative diseases. (Source: The Scientist)
Source: The Scientist - December 4, 2023 Category: Science Tags: Infographics Magazine Issue Source Type: news
Singing to babies is vital to help them learn language, say scientists
Study finds infants first understand language via rhythm and tone rather than individual soundsA, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P … How many would read this tothat tune?According to scientists from the University of Cambridge, there ’s more to the earworm than infuriating parents across the English-speaking world – they have found that singsong speech is crucial to helping babies learn language.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - December 1, 2023 Category: Science Authors: Jamie Grierson Tags: Language Education Children Science Neuroscience Parents and parenting Family Society Source Type: news
NIH puts hold on $30 million trial of potential stroke drug
Related article
Misconduct concerns, possible drug risks should stop major stroke trial, whistleblowers say
BY
Charles Piller
The National Institutes of Health (NIH) has paused the start of a major human trial of an experimental drug aimed at protecting the brain after stroke. At the same time, the agency launched an investigation into recently aired concerns about the drug’s safety and whether lab studies supporting its promise contain manipulated images and data.
The agency’s 16 November m...
Source: ScienceNOW - December 1, 2023 Category: Science Source Type: news
New CT, MR scanners and AI top GE HealthCare highlights at RSNA 2023
CHICAGO -- GE HealthCare (GEHC) brought new CT and MRI scanners and a range of AI software applications to McCormick Place for RSNA 2023. CT In CT, GEHC shined the spotlight on its Revolution Ascend scanner, which was first introduced at ECR in March. With onsite detector upgrades, Ascend can be upgraded from a 20-mm coverage system for routine scanning to a 40-mm coverage system that delivers better low-contrast detectability, according to the vendor. The scanner also comes with True Enhance DL, an AI-based application that generates deep learning-based monochromatic-like images from a single-energy x-ray acquisition....
Source: AuntMinnie.com Headlines - December 1, 2023 Category: Radiology Authors: Erik L. Ridley Tags: RSNA 2023 Source Type: news
Sleep Rhythms Prompt Long-term Memories
A bridge between neurons triggers longer, deeper sleep and memory formation in fly larvae. (Source: The Scientist)
Source: The Scientist - December 1, 2023 Category: Science Tags: Magazine Issue Source Type: news
This Antarctic penguin sleeps 11 hours a day —a few seconds at a time
For sleepy humans, nodding off can be inconvenient—say, during a boring lecture—or even downright dangerous, such as while driving a car. But for Antarctica’s nesting chinstrap penguins (
Pygoscelis antarcticus
), these secondslong bits of shuteye known as “microsleeps” may help them survive. These mininaps net the birds
about 11 hours of sleep per day
, potentially offering them a way to rest while remaining vigilant over their eggs and chicks, researchers report today in
Science
. The work could shine a light on how different animals adapt their dozing to cope with stressful...
Source: ScienceNOW - November 30, 2023 Category: Science Source Type: news
Tiny ‘anthrobots’ built from human cells could help heal the body
In the medicine of the future, molecular physicians built from a patient’s own cells might ferret out cancer, repair injured tissue, and even remove plaque from blood vessels. Researchers have now taken a step toward that vision: They’ve coaxed tracheal cells to form coordinated groups called organoids that can propel themselves with tiny appendages. When added to wounded neurons in the lab,
these “anthrobots” helped neurons repair themselves
.
The work, reported today in
Advanced Science
, “is amazing, and groundbreaking,” says Xi “Charlie” Ren, a tissue engineer at Carnegie Mello...
Source: ScienceNOW - November 30, 2023 Category: Science Source Type: news
Brain Study Suggests Traumatic Memories Are Processed as Present Experience
Traumatic memories had their own neural mechanism, brain scans showed, which may help explain their vivid and intrusive nature. (Source: NYT Health)
Source: NYT Health - November 30, 2023 Category: Consumer Health News Authors: Ellen Barry Tags: Research Post-Traumatic Stress Disorder Therapy and Rehabilitation Memory Psychology and Psychologists Brain Nature Neuroscience (Journal) your-feed-healthcare your-feed-science Source Type: news
The Evolutionary Origins of Psychedelics
Humans rely on a bevy of strange natural chemicals to liven up our food and drink, to endure pain, and to change our perspective. We use caffeine from coffee, tea, and yerba mate to stimulate our bodies and minds, capsaicin from red pepper flakes or isothiocyanates in horseradish or wasabi to enliven our food with spice, and codeine or morphine to endure the pain of injuries and surgeries.
Lately, though, some have also turned to psychedelics like psilocybin to change their perspectives. In fact, researchers are beginning to test if they could serve as new treatments for mental health disorders.
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Source: TIME: Health - November 29, 2023 Category: Consumer Health News Authors: Noah Whiteman Tags: Uncategorized freelance Source Type: news
William Yule obituary
Psychologist who pioneered the treatment of children after such disasters as the Zeebrugge ferry sinking and the King ’s Cross fireOn 6 March 1987, the Herald of Free Enterprise ferry set sail from the Belgian port of Zeebrugge heading for Dover. The bow doors were not shut and within seconds it flooded with seawater. It capsized and 193 passengers and crew died.Bill (William) Yule, who has died aged 83, was a child psychologist at the Institute of Psychiatry (now the Institute of Psychiatry, Psychology& Neuroscience) in London and head of clinical psychology at what was then the Bethlem Royal and Maudsley hospital. ...
Source: Guardian Unlimited Science - November 28, 2023 Category: Science Authors: Penny Warren Tags: Children's health Mental health Psychology People in science Society Source Type: news
USC neuroscientist faces scrutiny following allegations of data manipulation
Accusations against USC's Berislav Zlokovic were made by a small group of independent researchers and reported in the journal Science. (Source: Los Angeles Times - Science)
Source: Los Angeles Times - Science - November 24, 2023 Category: Science Authors: Corinne Purtill, Melody Petersen Source Type: news
