Recommendations Issued for HSCT in Multiple Myeloma
WEDNESDAY, March 20, 2019 -- A consensus statement for the use of hematopoietic stem cell transplantation (HSCT) in the treatment of multiple myeloma (MM) has been developed by Mayo Clinic physicians; the recommendations were published in the March... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 20, 2019 Category: Pharmaceuticals Source Type: news

Model Predicts Survival in Transplant-Ineligible Myeloma Patients
TUESDAY, March 19, 2019 -- For patients with multiple myeloma who are ineligible for stem cell transplantation, a risk profile can predict overall survival, according to a study recently published in The Lancet Haematology. Gordon Cook, Ph.D., from... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 19, 2019 Category: Pharmaceuticals Source Type: news

Pulmonary Fibrosis Foundation Warns Against Stem Cell Infusions Pulmonary Fibrosis Foundation Warns Against Stem Cell Infusions
The foundation calls for-profit stem cell centers'the modern-day equivalent of snake oil'and warned against having stem cell treatments except in clinical trials.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 19, 2019 Category: Consumer Health News Tags: Pulmonary Medicine News Source Type: news

Story of discovery: getting a Notch up on cord blood cell transplantation
Researchers supported by NIDDK have discovered key factors that promote blood stem cell growth and maturation, and, with these insights, have developed ways to expand the numbers of cells from cord blood for use in transplants. (Source: NIDDK News)
Source: NIDDK News - March 19, 2019 Category: Endocrinology Source Type: news

Zebrafish employ cellular shield to protect blood stem cells from damaging ultraviolet light
While studying the blood stem cells that reside in the kidney of the zebrafish embryo, researchers observed that cells called melanocytes were positioned above the stem cells in an umbrella pattern, and subsequently showed this umbrella served as a shield protecting stem cells from damaging ultraviolet (UV) light.  (Source: NIDDK News)
Source: NIDDK News - March 19, 2019 Category: Endocrinology Source Type: news

Scientists grow 'mini-brain on the move' that can contract muscle
Cambridge researchers grew ‘organoid’ that spontaneously connected to spinal cordScientists have grown a miniature brain in a dish with a spinal cord and muscles attached, an advance that promises to accelerate the study of conditions such as motor neurone disease.The lentil-sized grey blob of human brain cells were seen to spontaneously send out tendril-like connections to link up with the spinal cord and muscle tissue, which was taken from a mouse. The muscles were then seen to visibly contract under the control of the so-called brain organoid.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - March 18, 2019 Category: Science Authors: Hannah Devlin Science correspondent Tags: Neuroscience Medical research Biology Genetics Motor neurone disease Epilepsy Society Schizophrenia Mental health University of Cambridge Stem cells Source Type: news

Oscillation in muscle tissue
(Max Delbr ü ck Center for Molecular Medicine in the Helmholtz Association) When a muscle grows or a muscle injury heals, some of the stem cells develop into new muscle cells. A research team at the MDC led by Carmen Birchmeier has now described in the journal Genes& Development how this process is regulated by two proteins produced in an oscillatory manner. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 15, 2019 Category: International Medicine & Public Health Source Type: news

The arrhythmogenic potential of nerve agents and a cardiac safety profile of antidotes - a proof-of-concept study using human induced pluripotent stem cells derived cardiomyocytes (hiPSC-CM) - Amend N, Thiermann H, Worek F, Wille T.
The global use of organophosphorus compounds (OP) for pest control and nerve agents being used in military conflicts and for assassinations renders intoxications by these agents a public health concern. OP-poisoned patients often suffer from dysrhythmias w... (Source: SafetyLit)
Source: SafetyLit - March 14, 2019 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

The Lancet Retracts Cardiac Stem Cell Clinical Trial Paper
The publication of the SCIPIO trial is among many by Piero Anversa's lab that Harvard Medical School flagged for fraudulent data. (Source: The Scientist)
Source: The Scientist - March 14, 2019 Category: Science Tags: News & Opinion Source Type: news

eBook: Biopharma Manufacturing Trends 2019
How slow-motion trends are driving biopharma growth, the dangerous impact of unproven stem cell therapies and more. (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - March 14, 2019 Category: Pharmaceuticals Source Type: news

Study: Curcumin, a polyphenol in turmeric, can selectively target cancer stem cells
(Natural News) In the world of health foods and superfoods there are some that stand head and shoulders above the rest and could almost be labeled “miracle foods.” One of the most well-known of these amazing foods is curcumin, the polyphenol that gives turmeric its beautiful, bright yellow color. Used for thousands of years in... (Source: NaturalNews.com)
Source: NaturalNews.com - March 14, 2019 Category: Consumer Health News Source Type: news

Cancer: Drinking this type of tea may stop spread of breast cancer cells, new study shows
CANCER: Groundbreaking new medical research has shown drinking a certain type of tea has the potential to stop the spread of breast cancer stem cells. (Source: Daily Express - Health)
Source: Daily Express - Health - March 14, 2019 Category: Consumer Health News Source Type: news

Oscar Saxelby-Lee: Mum 'overwhelmed' by stem cell donor campaign
Thousands of people have registered to find a stem cell match for a five-year-old with leukaemia. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - March 14, 2019 Category: Consumer Health News Source Type: news

Experts Are Calling for a Ban on Gene Editing of Human Embryos. Here ’s Why They’re Worried
In November 2018, Chinese biophysicist Jiankui He stunned the world when he announced that he had used a controversial gene-editing technology, called CRISPR, to genetically alter the genes in embryos and give them immunity to HIV. The embryos were transferred to the woman who provided the eggs to create them, and twin girls were born. The move, considered highly experimental and unethical by most scientists around the world, prompted intense debate in the scientific community about not just the implications for the twins, but for society as well. When applied to human eggs, sperm and embryos, gene-editing technologies, of...
Source: TIME: Health - March 13, 2019 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized Genetics Source Type: news

Discovery of how organs form helps researchers to develop future diabetes treatments
(University of Copenhagen The Faculty of Health and Medical Sciences) In a new study, researchers at the University of Copenhagen show that the development of a certain type of immature stem cells -- also known as progenitor cells -- depends on the quantity of a special protein and interaction with other cells in the body. The new study has just been published in the scientific journal Developmental Cell. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 13, 2019 Category: International Medicine & Public Health Source Type: news

Hematopoietic stem cells: Making blood thicker than water
(Osaka University) An Osaka University-led team revealed that Ragnase-1 is a key regulator of the self-renewal and differentiation of hematopoietic stem and progenitor cells. Knockout of this gene in mice resulted in aberrant blood cell composition and hematopoiesis, and caused health-related outcomes such as low hemoglobin, enlarged spleen, and early death. This insight into blood cell homeostasis and differentiation could lead to treatments for diseases such as leukemia in which these regulatory processes go awry. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 13, 2019 Category: International Medicine & Public Health Source Type: news

Starving leukemia cells by targeting amino acids
(Emory Health Sciences) Eliminating ASCT2 selectively stops the growth of leukemia cells, while having limited effects on healthy blood cells and hematopoetic (blood-forming) stem cells. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 12, 2019 Category: Cancer & Oncology Source Type: news

Genetically encoded sensor isolates hidden leukemic stem cells
(American Friends of Tel Aviv University) Tel Aviv University researchers have devised a novel biosensor that can isolate and target leukemic stem cells. It can provide a prototype for precision oncology efforts to target patient-specific cells to fight the deadly disease. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 12, 2019 Category: Cancer & Oncology Source Type: news

Making Sense of Stem Cells, Fat Grafting in Plastic Surgery Making Sense of Stem Cells, Fat Grafting in Plastic Surgery
Find out what plastic surgeons need to know regarding the FDA regulations on fat grafting and stem-cell therapies and the responsible use of these entities.Plastic and Reconstructive Surgery (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - March 11, 2019 Category: Allergy & Immunology Tags: Plastic Surgery & Aesthetic Medicine Journal Article Source Type: news

New regulatory factor identified in bone formation
(Mary Ann Liebert, Inc./Genetic Engineering News) Researchers report the identification of a novel transcription factor that helps regulate the differentiation of mesenchymal stem cells into bone in mice. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - March 11, 2019 Category: Biology Source Type: news

Is this cruciferous vegetable the key to brain regeneration?
(Natural News) The human brain is always in a state of self-repair. Neural stem cells (NSC) naturally repair and replace aged and damaged nerve tissue. This natural process of brain regeneration is expedited by certain beneficial phyto-nutrients, and hampered by certain toxic elements. Common pollutants in air, water, food, and medicine (such as mercury and... (Source: NaturalNews.com)
Source: NaturalNews.com - March 9, 2019 Category: Consumer Health News Source Type: news

Tanzania: Tanzanians Advised Not to Loosen HIV Guard
[Daily News] THE government has warned Tanzanians against being loosen their guard, following recent reports from UK that HIV can be 'cured' after a stem cell transplant from a patient proved the disease can be treated. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - March 8, 2019 Category: African Health Source Type: news

Prospective drug found by testing in human heart muscle grown from stem cells
Scientists have found a potential new drug for treating the heart damage caused by a heart attack by targeting the way the heart reacts to stress, according to new research which used stem cells to grow heart tissue and mimic a heart attack in a dish. (Source: Medical Research Council General News)
Source: Medical Research Council General News - March 7, 2019 Category: Research Source Type: news

New research capitalizes on therapeutic promise of programmed cell death
(American Association for the Advancement of Science) Yaron Fuchs is the 2018 grand prize winner of the Sartorius& Science Prize for Regenerative Medicine& Cell Therapy, for work that reveals a role for programmed stem cell death in wound healing and tissue regeneration. The findings, described in his prize-winning essay, 'The therapeutic promise of apoptosis,' could potentially pave the way to novel regenerative medicine and tumor therapies that target stem cells undergoing apoptosis -- a type of programmed cell death. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 7, 2019 Category: Cancer & Oncology Source Type: news

Vitamin B3 analogue boosts production of blood cells
(Ecole Polytechnique F é d é rale de Lausanne) Scientists from EPFL and the UNIL/Ludwig Cancer Research have found that supplementing diet with nicotinamide riboside, an analogue of vitamin B3, boosts the production of blood cells by improving the function of their stem cells. This can help overcome problems in stem cell-based therapies that treat leukemia and aggressive lymphomas. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 7, 2019 Category: Cancer & Oncology Source Type: news

Embryos' signals take multiple paths
(Rice University) Rice University bioscientists uncover details about how embryonic stem cells respond to the collection of signals that direct their differentiation into blood, bone and tissue. They found two critical signaling pathways are treated differently by cells. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - March 7, 2019 Category: Biology Source Type: news

Is WBRT or ASCT Better Consolidation for Younger Patients With CNS Lymphoma?
The PRECIS study looked at consolidation treatment with autologous stem cell transplantation vs whole-brain radiation therapy in younger patients with CNS lymphoma. (Source: CancerNetwork)
Source: CancerNetwork - March 7, 2019 Category: Cancer & Oncology Authors: Leah Lawrence Source Type: news

Fats enhance stem cell emergence
(Source: ScienceNOW)
Source: ScienceNOW - March 7, 2019 Category: Science Authors: Rajan, V., Berman, J. N. Tags: perspective Source Type: news

Two patients with HIV are in remission. How many more will follow them?
And then there were two.A London man infected with HIV has gone into long-term remission after getting a special stem cell transplant that not only treated his cancer, it sent the virus into remission as well. His recovery,described this week in the journal Nature, marks the second time a patient... (Source: Los Angeles Times - Science)
Source: Los Angeles Times - Science - March 6, 2019 Category: Science Authors: Melissa Healy Source Type: news

Stem Cell Therapies for Alzheimer's Disease: Is It Time? Stem Cell Therapies for Alzheimer's Disease: Is It Time?
Stem cell therapy has shown promise as a potential treatment for Alzheimer's disease patients, but more research is needed. How close are we?Current Opinion in Psychiatry (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 6, 2019 Category: Consumer Health News Tags: Psychiatry Journal Article Source Type: news

Improving Preclinical Discovery of CRISPR Engineered Immune Cell Therapies
There is an urgent need to characterize the potency and efficacy of CRISPR-Cas9-modified inducible pluripotent stem cell-derived natural killer cells for preclinical cancer immunotherapy research.... (Source: The Scientist)
Source: The Scientist - March 6, 2019 Category: Science Tags: The Marketplace Source Type: news

Africa: Second Patient 'In Remission' from HIV After Stem-Cell Therapy
[This is Africa] A second patient has reportedly been cured of HIV, after stem-cell therapy, which could be a major milestone in the global fight against the AIDS epidemic. The report was released in the scientific journal Nature, and offers hope that a cure for HIV could be possible in the future, and not just a pipe dream. (Source: AllAfrica News: HIV-Aids and STDs)
Source: AllAfrica News: HIV-Aids and STDs - March 6, 2019 Category: Infectious Diseases Source Type: news

Effects of spaceflight on heart cell formation from stem cells
(Mary Ann Liebert, Inc./Genetic Engineering News) Researchers used time-lapse imaging to show that mouse induced pluripotent stem cells (iPSCs) grown during spaceflight differentiated into cardiomyocytes significantly faster than similar cells grown at Earth's gravity. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 6, 2019 Category: International Medicine & Public Health Source Type: news

London man seems to be free of HIV in second such case
London man appears to be free of the AIDS virus after a stem cell transplant, the second such success (Source: ABC News: Health)
Source: ABC News: Health - March 6, 2019 Category: Consumer Health News Tags: Health Source Type: news

2nd man apparently free of AIDS virus after stem cell transplant
The procedure has been called dangerous and has failed in other patients; the patient from London hasn't been identified (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - March 5, 2019 Category: Consumer Health News Source Type: news

2nd ever HIV patient in remission after transplant: Doctors
A British man who previously tested positive for HIV has shown no trace of the virus that causes AIDs since receiving a stem cell transplant more than a year ago. (Source: ABC News: Health)
Source: ABC News: Health - March 5, 2019 Category: Consumer Health News Tags: Health Source Type: news

Second Man HIV-Free After Stem Cell Transplant
TUESDAY, March 5, 2019 -- In only the second known case worldwide, a man is free of HIV after a stem cell transplant, doctors say. The London patient has not been identified. He was diagnosed with HIV in 2013 and diagnosed with Hodgkin lymphoma in... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 5, 2019 Category: Pharmaceuticals Source Type: news

London patient ‘free’ of HIV after stem cell transplant
Man treated in UK is only the second person ever to go into remission from the virus (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - March 5, 2019 Category: Pharmaceuticals Source Type: news

Second Man Is HIV-Free After Stem Cell Transplant
In only the second known case worldwide, a man is free of HIV after a stem cell transplant, doctors say. (Source: WebMD Health)
Source: WebMD Health - March 5, 2019 Category: Consumer Health News Source Type: news

Are Stem Cell Transplants A Cure For HIV? Not So Fast
Promising news, as a second patient with HIV has a long-lasting " cure " following stem cell transplantation. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - March 5, 2019 Category: Pharmaceuticals Authors: Judy Stone, Contributor Source Type: news

Are Stem Cell Transplants A Cure For HIV?
Promising news, as a second patient with HIV has a long-lasting " cure " following stem cell transplantation. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - March 5, 2019 Category: Pharmaceuticals Authors: Judy Stone, Contributor Source Type: news

Treosulfan Better Than Busulfan in Prep for HSCT Treosulfan Better Than Busulfan in Prep for HSCT
Older and sicker patients with acute myeloid leukemia undergoing stem cell transplant may fare better if they are given a treosulfan- rather than busulfan-based regimen, German scientists have shown.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - March 5, 2019 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

2nd man seems to be free of virus that causes AIDS after transplant
A man in London appears to be free of the AIDS virus after a stem cell transplant, the second such success, doctors report. (Source: CBC | Health)
Source: CBC | Health - March 5, 2019 Category: Consumer Health News Tags: News/Health Source Type: news

Second HIV Patient May Be Cured After Transplant
TUESDAY, March 5, 2019 -- Doctors say they have sent a second HIV patient into what might be permanent remission using a stem cell transplant. The news comes a decade after the first case of a cure was reported. Back in 2009, doctors published a... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - March 5, 2019 Category: General Medicine Source Type: news

First man cleared of HIV by stem cell treatment speaks of hope for others - video
The first known case of a functional cure for HIV happened 12 years ago, after US resident Timothy Brown received stem cell donations in Berlin. More recently, a patient in London received a bone marrow transplant from a virus-resistant donor and has been shown to be cleared of the virusContinue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - March 5, 2019 Category: Science Tags: Aids and HIV Medical research Health London UK news Society US news Science Source Type: news

2nd man apparently free of AIDS virus following stem cell transplant
The procedure has been called dangerous and has failed in other patients; the patient from London hasn't been identified (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - March 5, 2019 Category: Consumer Health News Source Type: news

Health Highlights: March 5, 2019
Here are some of the latest health and medical news developments, compiled by the editors of HealthDay: Second Man HIV-Free After Stem Cell Transplant In only the second known case worldwide, a man is free of HIV after a stem cell transplant,... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - March 5, 2019 Category: General Medicine Source Type: news

UK patient 'free' of HIV after stem cell treatment
The patient has shown no sign of the virus for nearly 19 months since having the treatment. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - March 5, 2019 Category: Consumer Health News Source Type: news

Second Man HIV-Free After Stem Cell Transplant
Title: Second Man HIV-Free After Stem Cell TransplantCategory: Health NewsCreated: 3/5/2019 12:00:00 AMLast Editorial Review: 3/5/2019 12:00:00 AM (Source: MedicineNet HIV General)
Source: MedicineNet HIV General - March 5, 2019 Category: Infectious Diseases Source Type: news

Second man seems to be free of AIDS virus after transplant
London man appears to be free of the AIDS virus after a stem cell transplant, the second such success (Source: ABC News: Health)
Source: ABC News: Health - March 5, 2019 Category: Consumer Health News Tags: Health Source Type: news