Vertex Pharmaceuticals to Acquire Alpine Immune Sciences for $4.9 Billion
Transaction would give the pharmaceutical giant access to Alpine’s potential treatment for chronic kidney disease. (Source: Reuters: Health)
Source: Reuters: Health - April 10, 2024 Category: Consumer Health News Source Type: news

Roche and Alnylam present positive results from the Phase II KARDIA-2 study of zilebesiran added to standard of care antihypertensives in patients with inadequately controlled hypertension
The KARDIA-2 study met its primary endpoint demonstrating additive, placebo-adjusted systolic blood pressure reductions of up to 12.1 mmHgat month three. These results were statistically significant and clinically meaningfulZilebesiran demonstrated an encouraging safety and tolerability profile when added to standard of care antihypertensives Basel, 7 April 2024 - Roche (SIX: RO, ROG; OTCQX: RHHBY) and Alnylam today released detailed results from the Phase II KARDIA-2 study evaluating the efficacy and safety of a single subcutaneous dose of zilebesiran when added to one of three standard of care (SOC) antihypertensives. T...
Source: Roche Investor Update - April 7, 2024 Category: Pharmaceuticals Source Type: news

Groups Ask WHO to Recognize Chronic Kidney Disease Threat Groups Ask WHO to Recognize Chronic Kidney Disease Threat
Three international nephrology organizations call for World Health Organization recognition of CKD as a major noncommunicable mortality driver.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 5, 2024 Category: Consumer Health News Tags: Nephrology Source Type: news

EHR-Based Algorithm Does Not Cut Hospitalization in Kidney Dysfunction Triad
THURSDAY, April 4, 2024 -- For patients with the triad of chronic kidney disease, type 2 diabetes, and hypertension, the use of an electronic health record-based algorithm and intervention does not result in reduced hospitalization at one year,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 4, 2024 Category: Pharmaceuticals Source Type: news

Primary Care Strategy Fails to Reduce Kidney-Dysfunction Triad Hospitalizations
(MedPage Today) -- Using a personalized algorithm to identify primary care patients with chronic kidney disease (CKD), type 2 diabetes, and hypertension (the kidney-dysfunction triad) -- plus practice facilitators to help providers deliver guideline... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - April 4, 2024 Category: Cardiology Source Type: news

CKD Progress Risk Increased Even if Albuminuria Range Normal CKD Progress Risk Increased Even if Albuminuria Range Normal
A linear increase in the risk for chronic kidney disease progression is observed even in albuminuria ranges (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 2, 2024 Category: Consumer Health News Tags: Nephrology Source Type: news

CKD Progression Risk Up With Increasing Albuminuria in Normal Range
MONDAY, April 1, 2024 -- For people with chronic kidney disease (CKD) and normoalbuminuria, the risk for CKD progression increases with higher levels of albuminuria, according to a study published online April 2 in the Annals of Internal... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 1, 2024 Category: Pharmaceuticals Source Type: news

Once-Rejected Drug Now FDA Approved for CKD-Related Anemia
(MedPage Today) -- The FDA approved vadadustat (Vafseo) for chronic kidney disease (CKD)-related anemia in adults who have been on dialysis for at least 3 months, developer Akebia Therapeutics announced on Wednesday. "Patients receiving maintenance... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 28, 2024 Category: Hematology Source Type: news

Study Reveals Glucagon Receptors' Role in Renal Health Study Reveals Glucagon Receptors' Role in Renal Health
In findings with implications for future therapies in chronic kidney disease, mouse studies show a protective effect of glucagon receptor signaling in the kidney.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 28, 2024 Category: Consumer Health News Tags: Nephrology Source Type: news

Two years after initial rejection, Akebia ’s anemia drug finally gets FDA approval
The FDA approved the Cambridge biotech's drug vadadustat for the treatment of anemia due to chronic kidney disease in adults who have been receiving dialysis for at least three months. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - March 28, 2024 Category: Biotechnology Authors: Hannah Green Source Type: news

FDA Approves Vafseo (vadadustat) for the Treatment of Anemia due to Chronic Kidney Disease in Adult Patients on Dialysis
CAMBRIDGE, Mass., March 27, 2024 /PRNewswire/ -- Akebia Therapeutics, Inc. (Nasdaq: AKBA), a biopharmaceutical company with the purpose to better the lives of people impacted by kidney disease, today announced that the U.S. Food and Drug... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - March 27, 2024 Category: Drugs & Pharmacology Source Type: news

Rwanda: Kayonza Survey - 10 Percent of Patients With NCDs Unknowingly Have Chronic Kidney Disease
[New Times] A team of doctors and nurses from Rwinkwavu Hospital and Partners in Health collected blood and urine samples to study the occurrence of chronic kidney disease in 1,268 patients with hypertension, 1,189 with HIV, and 582 with other non-communicable diseases (NCDs) across two phases. The study revealed that more than 300 patients out of 3,039 tested positive for chronic kidney disease. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - March 26, 2024 Category: African Health Tags: Central Africa East Africa Health and Medicine Rwanda Source Type: news

How to keep your kidneys working well
Kidney damage can ’t be reversed, but there are lifestyle steps and treatments that can help keep chronic kidney disease in check. (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - March 25, 2024 Category: Consumer Health News Authors: Ashley Abramson, Halle Levine Source Type: news

Systemic Inflammation Increases Risk for Chronic Kidney Disease
FRIDAY, March 22, 2024 -- Systemic inflammation is associated with an elevated risk for chronic kidney disease, according to a study published online Feb. 20 in Frontiers in Immunology. Xiaoxin Liu, from Tongji Medical College at the Huazhong... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 22, 2024 Category: Pharmaceuticals Source Type: news

Chronic kidney disease duration and suicide risk among maintenance hemodialysis patients in China - Wang X, Hao X, Ma M, Jiang W, Li B, Xu Y, Sun P.
BACKGROUND: Our aim was to investigate the relationship between chronic kidney disease (CKD) duration and suicide risk among maintenance hemodialysis patients in China. METHODS: Patients with end-stage renal disease (ESRD) who received MHD were enr... (Source: SafetyLit)
Source: SafetyLit - March 22, 2024 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news