Global heating ‘may lead to epidemic of kidney disease’
Deadly side-effect of heat stress is threat to rising numbers of workers in hot climates, doctors warn‘You shouldn’t work if your kidneys are failing – but people can’t afford not to’Read more in theHarmed by heat seriesChronic kidney disease linked to heat stress could become a major health epidemic for millions of workers around the world as global temperatures increase over the coming decades, doctors have warned.More research into the links between heat and CKDu – chronic kidney disease of uncertain cause – is urgently needed to assess the potential scale of the problem, they h...
Source: Guardian Unlimited Science - October 21, 2021 Category: Science Authors: Natalie Grover Tags: Global health Science Workers' rights Americas Global development Nicaragua El Salvador Agriculture Diabetes Human rights High blood pressure Society World news Cop26 Source Type: news

Three UCLA faculty members elected to National Academy of Medicine
Three faculty members of theDavid Geffen School of Medicine at UCLA have been elected to the National Academy of Medicine, among the highest honors in the fields of medicine and health.New members are elected by their peers through a process that recognizes individuals who have demonstrated outstanding professional achievement and commitment to service.The honorees are:Dr. Helena Hansen, professor of psychiatry and biobehavioral sciences. She co-chairs the medical school ’s Research Theme in Health Equity and Translational Social Science, which cultivates research collaborations between social and biomedica...
Source: UCLA Newsroom: Health Sciences - October 19, 2021 Category: Universities & Medical Training Source Type: news

FDA approves drug to reduce risk of serious kidney and heart complications in adults with chronic kidney disease associated with type 2 diabetes
FDA has approved Kerendia (finerenone) tablets to reduce the risk of kidney function decline, kidney failure, cardiovascular death, non-fatal hearts attacks, and hospitalization for heart failure in adults with chronic kidney disease associated with type 2 diabetes. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - September 30, 2021 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Can radiomics and AI characterize renal masses on preop CT?
The combination of radiomics and a machine-learning algorithm can differentiat...Read more on AuntMinnie.comRelated Reading: Deep-learning algorithm spots kidney stones on CT exams CT shows that acute kidney injury common among COVID-19 patients Ultrasound AI model can help evaluate chronic kidney disease AI plus CT improves liver steatosis assessment AI could help radiologists better detect kidney cancer (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - September 17, 2021 Category: Radiology Source Type: news

What Are the Advantages and Disadvantages of Different Renal Replacement Therapies?
Discussion Kidneys are amazing in that they filter the blood, eliminate toxins, balance fluids and electrolytes plus have a lot of reserve to do the job they need to do even when injured. Therefore, depending on the problem, chronic renal disease (CRD) often allows time before renal replacement therapy (RRT) is needed. RRT currently is dialysis (peritoneal or hemodialysis) or renal transplant. In general, the patient’s own kidneys do the best job for them but there is always a balance between the problems of CRD and its management, versus the potentially improved renal function with RRT. RRT itself though has a diffe...
Source: PediatricEducation.org - September 13, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Chronic Kidney Disease May Be Overestimated in the Elderly
WEDNESDAY, Sept. 8, 2021 -- Current chronic kidney disease (CKD) definitions that do not consider age-related estimated glomerular filtration rate (eGFR) decline may inflate the burden of CKD in the elderly, according to a study published online... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - September 8, 2021 Category: Pharmaceuticals Source Type: news

Chronic Kidney Disease Definition Likely Inflates Disease Burden Chronic Kidney Disease Definition Likely Inflates Disease Burden
The current guideline-defined chronic kidney disease definition, which does not consider age-related eGFR decline, likely results in overdiagnosis among adults 65 and older, researchers suggest.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 7, 2021 Category: Consumer Health News Tags: Nephrology News Source Type: news

T Scores, FRAX, frailty phenotype, falls, and its relationship to fractures in patients on maintenance hemodialysis - Jafari M, Anwar S, Kour K, Sanjoy S, Goyal K, Prasad B.
BACKGROUND: Despite the magnitude of fracture and the consequences in patients receiving hemodialysis, optimal risk assessment tools in this population are not well explored. Frailty and falls-known risk factors for fracture in chronic kidney disease (CKD)... (Source: SafetyLit)
Source: SafetyLit - September 4, 2021 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Removing Race Term From CKD-EPI Could Worsen Cancer Care for Blacks
WEDNESDAY, Sept. 1, 2021 -- Removing race from the Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI) equation will calculate a lower estimated glomerular filtration rate (eGFR) for Black patients and exclude more from receiving... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - September 1, 2021 Category: Pharmaceuticals Source Type: news

New-Data-Finerenone-protection-patients-chronic-kidney-disease-2-diabetes-cardiovascular-events
(Source: Bayer Company News)
Source: Bayer Company News - August 28, 2021 Category: Pharmaceuticals Source Type: news

Contrast ultrasound can predict treatment failure of bone fractures
Contrast-enhanced ultrasound can predict treatment failure for bone fracture...Read more on AuntMinnie.comRelated Reading: Ultrasound societies say 'no change' to contrast agent policy Researchers tout promise of contrast ultrasound at AIUM 2021 CEUS liver guidelines get first update in 8 years Review: CEUS bests CT, MRI for liver disease CEUS helps predict chronic kidney disease progression (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - August 25, 2021 Category: Radiology Source Type: news

Ultrasound needs improvements for pediatric renal imaging
Traditional ultrasound surveillance may give a false sense of security whe...Read more on AuntMinnie.comRelated Reading: Ultrasound can determine lung congestion in kidney patients Shorter lung ultrasound exams can help kidney disease patients Ultrasound AI model can help evaluate chronic kidney disease Exposure to contrast on CTPA doesn't cause long-term kidney injury CEUS helps predict chronic kidney disease progression (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - August 24, 2021 Category: Radiology Source Type: news

Roxadustat Treats Anemia in Non-Dialysis-Dependent CKD
MONDAY, Aug. 23, 2021 -- For patients with non-dialysis-dependent chronic kidney disease (CKD) and CKD-related anemia, roxadustat increases hemoglobin levels and reduces the need for red blood cell transfusions, according to a study published in the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 23, 2021 Category: Pharmaceuticals Source Type: news

After stalling in the U.S., FibroGen anemia drug wins European nod and $120M partner payout
The drug is approved for chronic kidney disease patients in Europe, Japan, China, Chile and South Korea but was rejected earlier this month by U.S. regulators. (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - August 20, 2021 Category: Pharmaceuticals Authors: Ron Leuty Source Type: news

After stalling in the U.S., FibroGen anemia drug wins European nod and $120M partner payout
The drug is approved for chronic kidney disease patients in Europe, Japan, China, Chile and South Korea but was rejected earlier this month by U.S. regulators. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - August 20, 2021 Category: Biotechnology Authors: Ron Leuty Source Type: news

Chronic Kidney Disease Tied to Worse LAAO Outcomes Chronic Kidney Disease Tied to Worse LAAO Outcomes
The findings from a nationwide study echo those seen with other cardiac interventions and highlight the pressing need for more data in this high-risk group, experts say.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - August 18, 2021 Category: Cardiology Tags: Cardiology News Source Type: news

High BMI Variability, Adverse Outcomes Linked in Predialysis CKD
FRIDAY, Aug. 13, 2021 -- For predialysis chronic kidney disease (CKD) patients, those with high body mass index (BMI) variability have an increased risk for adverse outcomes, including mortality, according to a study published online Aug. 12 in the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 13, 2021 Category: Pharmaceuticals Source Type: news

FibroGen Receives Complete Response Letter from the FDA for Roxadustat for Anemia of Chronic Kidney Disease
SAN FRANCISCO, Aug. 11, 2021 (GLOBE NEWSWIRE) -- FibroGen, Inc. (NASDAQ: FGEN) today announced that the U.S. Food and Drug Administration (FDA) has issued a complete response letter regarding the New Drug Application... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - August 11, 2021 Category: Drugs & Pharmacology Source Type: news

EU Approves Dapagliflozin for Kidney Disease, Regardless of Diabetes EU Approves Dapagliflozin for Kidney Disease, Regardless of Diabetes
The decision rested on results from the DAPA-CKD pivotal trial and followed US FDA approval last April for adults with chronic kidney disease regardless of whether they also have type 2 diabetes.International Approvals (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - August 10, 2021 Category: Transplant Surgery Tags: Diabetes & Endocrinology News Alert Source Type: news

Metabolic Syndrome May Worsen Outcomes in Chronic Kidney Disease
MONDAY, Aug. 9, 2021 -- Metabolic syndrome may increase the risk for all-cause mortality and cardiovascular events in patients with moderate chronic kidney disease (CKD), according to a study published Aug. 3 in the Journal of Internal... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 9, 2021 Category: Pharmaceuticals Source Type: news

Prescription drug overdose, depression, and other mental disorders in the context of kidney disease - Menezes RRPPB, Sampaio TL, Martins AMC, de Sousa Alves R, Magalh ães EP.
Clinical Background: Mental disorders, especially depression, are associated with several comorbidities in the kidneys. Depression is the psychiatric disorder that mostly affects individuals with chronic kidney disease (CKD) and end-stage kidney disease. E... (Source: SafetyLit)
Source: SafetyLit - August 5, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Challenge of Implementing Sustained Sodium Reductions in CKD Challenge of Implementing Sustained Sodium Reductions in CKD
Reducing sodium intake is important for those with chronic kidney disease, so why is implementing these recommendations so difficult?Nephrology Dialysis Transplantation (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - August 2, 2021 Category: Transplant Surgery Tags: Nephrology Journal Article Source Type: news

Caring for the Resident with Complex Medical Needs in Assisted Living
Mr. P is an 89-year-old Black man who transitioned to assisted living after an acute hospitalization for pneumonia and then a short stay in post-acute care for therapy and to stabilize his chronic medical problems. Before that time he had been living independently, but he was hospitalized three times over the past year due to exacerbations of congestive heart failure and his underlying restrictive pulmonary disease (COPD). His additional medical history includes hyponatremia, chronic kidney disease, and anxiety. (Source: Caring for the Ages)
Source: Caring for the Ages - August 1, 2021 Category: Health Management Authors: Barbara Resnick, Paige Hector Tags: IDT Case Studies Source Type: news

Monthly News Roundup - July 2021
Kerendia Cleared to Treat Chronic Kidney Disease Linked with Type 2 Diabetes In July, the FDA approved Bayer’s Kerendia (finerenone) from Bayer, a first-in-class non-steroidal, selective mineralocorticoid receptor antagonist (MRA) for the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 31, 2021 Category: Pharmaceuticals Source Type: news

Race-Free Equations for Glomerular Filtration Rate Compared
FRIDAY, July 30, 2021 -- The chronic kidney disease (CKD) Epidemiology Consortium estimated glomerular filtration rate cystatin C (eGFRcys), the only guideline-recommended equation that does not require race, results in the smallest changes to eGFR... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 30, 2021 Category: Pharmaceuticals Source Type: news

Family Doctors Omit Tests for Kidney Disease in Type 2 Diabetes Family Doctors Omit Tests for Kidney Disease in Type 2 Diabetes
US primary care physicians are not properly checking patients with type 2 diabetes for chronic kidney disease nearly as often as they should, meaning many miss getting a timely diagnosis.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - July 30, 2021 Category: Cardiology Tags: Nephrology News Source Type: news

No Increase in Risk With Dapagliflozin in Patients With Stage 4 CKD
WEDNESDAY, July 21, 2021 -- For patients with stage 4 chronic kidney disease (CKD), a similar pattern of reduced kidney, cardiovascular, and mortality risks is seen with dapagliflozin versus placebo, with no evidence of increased risks, according to... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 21, 2021 Category: Pharmaceuticals Source Type: news

A Fremont drug maker's stock tumbled 76% after the FDA dissed its kidney drug
Ardelyx Inc.'s attempt to win a second drug approval was beat back by federal regulators, sending its stock down as much as 76% Tuesday. The Fremont company (NASDAQ: ARDX) had hoped to win Food and Drug Administration approval for tenapanor as a treatment for hyperphosphatemia, a life-threatening surge of phosphates in the blood of adult chronic kidney disease patients on dialysis. But Ardelyx revealed Monday that it received a let ter from the FDA on July 13 identifying "deficiencies" in its approval… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - July 20, 2021 Category: Pharmaceuticals Authors: Ron Leuty Source Type: news

A Fremont drug maker's stock tumbled 76% after the FDA dissed its kidney drug
Ardelyx Inc.'s attempt to win a second drug approval was beat back by federal regulators, sending its stock down as much as 76% Tuesday. The Fremont company (NASDAQ: ARDX) had hoped to win Food and Drug Administration approval for tenapanor as a treatment for hyperphosphatemia, a life-threatening surge of phosphates in the blood of adult chronic kidney disease patients on dialysis. But Ardelyx revealed Monday that it received a let ter from the FDA on July 13 identifying "deficiencies" in its approval… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - July 20, 2021 Category: Biotechnology Authors: Ron Leuty Source Type: news

East Bay drug maker tumbles 76% after FDA disses kidney drug
Ardelyx Inc.'s attempt to win a second drug approval was beat back by federal regulators, sending its stock down as much as 76% Tuesday. The Fremont company (NASDAQ: ARDX) had hoped to win Food and Drug Administration approval for tenapanor as a treatment for hyperphosphatemia, a life-threatening surge of phosphates in the blood of adult chronic kidney disease patients on dialysis. But Ardelyx revealed Monday that it received a let ter from the FDA on July 13 identifying "deficiencies" in the company's… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - July 20, 2021 Category: Pharmaceuticals Authors: Ron Leuty Source Type: news

East Bay drug maker tumbles 76% after FDA disses kidney drug
Ardelyx Inc.'s attempt to win a second drug approval was beat back by federal regulators, sending its stock down as much as 76% Tuesday. The Fremont company (NASDAQ: ARDX) had hoped to win Food and Drug Administration approval for tenapanor as a treatment for hyperphosphatemia, a life-threatening surge of phosphates in the blood of adult chronic kidney disease patients on dialysis. But Ardelyx revealed Monday that it received a let ter from the FDA on July 13 identifying "deficiencies" in the company's… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - July 20, 2021 Category: Biotechnology Authors: Ron Leuty Source Type: news

Hip fracture risk in elderly with non-end-stage chronic kidney disease: a fall related analysis - Covino M, Vitiello R, De Matteis G, Bonadia N, Piccioni A, Carbone L, Zaccaria R, Cauteruccio M, Ojetti V, Franceschi F.
BACKGROUND: The aim of this study was to evaluate the risk of fracture as a consequence of trauma and its association with kidney function status in a cohort of elderly patients. METHODS: This is an observational, cross-sectional study. We evaluate... (Source: SafetyLit)
Source: SafetyLit - July 17, 2021 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

FDA Panel Rejects Roxadustat for Anemia in Kidney Disease FDA Panel Rejects Roxadustat for Anemia in Kidney Disease
An FDA advisory committee voted by 1-13 and 2-12 margins against approving a novel, oral agent, roxadustat, for treating anemia in patients with chronic kidney disease. Safety was the major issue.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 16, 2021 Category: Consumer Health News Tags: Nephrology News Source Type: news

Status on FDA Advisory Committee Vote on Roxadustat in Anemia of Chronic Kidney Disease
16 July 2021 -- The Food and Drug Administration’s (FDA) Cardiovascular and Renal Drugs Advisory Committee (CRDAC) has voted 13 to 1 that the benefit-risk profile of roxadustat does not support approval for the treatment of anemia in chronic... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - July 16, 2021 Category: Drugs & Pharmacology Source Type: news

New guidance on how to diagnosis and manage osteoporosis in chronic kidney disease
(International Osteoporosis Foundation) This new review by the International Osteoporosis Foundation (IOF) and European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) CKD-MBD working group provides concise recommendations, with a clear management algorithm, to support clinicians' knowledge and confidence in managing osteoporosis in their patients with chronic kidney disease stages 4-5D. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 15, 2021 Category: International Medicine & Public Health Source Type: news

Iron Deficiency May Increase Mortality, CV Risks in Nondialysis CKD
WEDNESDAY, July 14, 2021 -- For patients with nondialysis chronic kidney disease (CKD), with or without anemia, iron deficiency as reflected by a serum biomarker of iron stores is associated with an increased risk for all-cause mortality and major... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 14, 2021 Category: Pharmaceuticals Source Type: news

Allocating COVID vaccines based on health and socioeconomic factors could cut mortality
(Columbia University's Mailman School of Public Health) An estimated 43 percent of variability in U.S. COVID-19 mortality is linked with county-level socioeconomic indicators and health vulnerabilities, with the strongest association seen in the proportions of people living with chronic kidney disease and living in nursing homes. The study by Columbia University Mailman School of Public Health researchers suggests that allocating vaccines based on these factors could help minimize severe outcomes, particularly deaths. Results are published in the open-access journal PLOS Medicine. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 13, 2021 Category: Infectious Diseases Source Type: news

Iron Therapy May Help More Patients With Kidney Disease Iron Therapy May Help More Patients With Kidney Disease
Treating iron deficiency in patients with chronic kidney disease but without anemia may reduce their risk of death, particularly from cardiovascular causes, new research hints.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 12, 2021 Category: Consumer Health News Tags: Nephrology News Source Type: news

FDA Approves Kerendia (finerenone) for the Treatment of Patients with Chronic Kidney Disease Associated with Type 2 Diabetes
WHIPPANY, N.J.-- July 9, 2021 (BUSINESS WIRE)-- Bayer announced today the United States (U.S.) Food and Drug Administration (FDA) has approved Kerendia (finerenone), a first-in-class nonsteroidal mineralocorticoid receptor antagonist (MRA) indicated... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - July 9, 2021 Category: Drugs & Pharmacology Source Type: news

US-FDA-approves-finerenone-treatment-patients-chronic-kidney-disease-associated-2-diabetes
Finerenone is the first non-steroidal, selective mineralocorticoid receptor (MR) antagonist to demonstrate positive kidney and cardiovascular outcomes in patients with chronic kidney disease associated with type 2 diabetes / Despite guideline-directed therapies, many patients with chronic kidney disease (CKD) associated with type 2 diabetes (T2D) still progress to loss of kidney function and are at high risk for cardiovascular events / By blocking MR overactivation, a key driver of CKD progression, finerenone works on a pathway largely unaddressed by existing treatments for CKD in T2D (Source: Bayer Company News)
Source: Bayer Company News - July 9, 2021 Category: Pharmaceuticals Source Type: news

FDA Approves Drug to Reduce Risk of Serious Kidney and Heart Complications in Adults with Chronic Kidney Disease Associated with Type 2 Diabetes
FDA has approved Kerendia (finerenone) tablets to reduce the risk of kidney function decline, kidney failure, cardiovascular death, non-fatal hearts attacks, and hospitalization for heart failure in adults with chronic kidney disease associated with type 2 diabetes. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - July 9, 2021 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Association of Positive Fluid Balance at Discharge After Sepsis Management With 30-Day Readmission
Conclusions and Relevance: In this large observational study of non–critically ill patients hospitalized with sepsis, there was no association between posi tive fluid balance at the time of discharge and readmission. However, these findings may have been limited by variable recording and documentation of fluid intake and output; additional studies are needed to examine the association of fluid status with outcomes in patients with sepsis to reduce read mission risk. This cohort study evaluates whether positive fluid balance among non–critically ill patients with sepsis was associated with increased readmission ...
Source: Current Awareness Service for Health (CASH) - July 9, 2021 Category: Consumer Health News Source Type: news

Why this anti-aging drug startup thinks it's barking up the right tree
Biotech's efforts to extend life through drugs is going to the dogs. A San Francisco startup, backed by Laura Deming's anti-aging Longevity Fund, plans to take its first drug into clinical trials soon, using an existing drug to target a cellular mechanism believed to be responsible for large and giant breed dogs aging faster than smaller dogs. A second drug, aimed at "doggy dementia" and chronic kidney disease, also is expected to start a study in dogs this year. Cellular Longevity Inc. — or… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - July 9, 2021 Category: American Health Authors: Ron Leuty Source Type: news

Not So Crazy: Pancreas Transplants in Type 2 Diabetes Rising Not So Crazy: Pancreas Transplants in Type 2 Diabetes Rising
Simultaneous pancreas-kidney transplants are increasingly performed in patients with type 2 diabetes and chronic kidney disease, who now account for about 20% of all pancreas transplants in the US.Medscape Medical News (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - July 8, 2021 Category: Transplant Surgery Tags: Diabetes & Endocrinology News Source Type: news

The Role of Activin: The Other Side of CKD-MBD? The Role of Activin: The Other Side of CKD-MBD?
A new review explores the potential role of activin A in the development of mineral bone disorder in patients with chronic kidney disease.Nephrology Dialysis Transplantation (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 7, 2021 Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news

What Problems are Ciliopathies Associated With?
Discussion Nephronophthisis (NPHP) one cause of end-stage renal disease (ESRD) usually occurring before age 30 years. NPHP is a non-motile ciliopathy affecting cellular sensing in the renal tubular epithelium. See To Learn More below. The incidence varies according to location with 1:1 million in the US but 1:50,000 in Finland. There are 3 subtypes: Infantile Occurs usually within 1 year of life Enlarged kidneys and severe hypertension In utero can have oligohydramnios problems such as pulmonary hypoplasia, facial dysmorphisms, limb contractures Extra-renal problems include congenital heart disease, liver fibrosis, recur...
Source: PediatricEducation.org - July 5, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Innovative Kidney Donor'Voucher' System Is Saving Lives
THURSDAY, June 24, 2021 -- In the world of chronic kidney disease, the dilemma is not uncommon: A relatively young patient with kidney trouble may need a transplant down the road, and an older family member is more than ready to step up. But the... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - June 24, 2021 Category: General Medicine Source Type: news

Guidelines Updated for Managing BP in CKD Patients Not on Dialysis
TUESDAY, June 22, 2021 -- For patients with high blood pressure (BP) and chronic kidney disease (CKD) who are not receiving dialysis, a systolic BP of
Source: Drugs.com - Pharma News - June 22, 2021 Category: Pharmaceuticals Source Type: news

FDA Approves SOAANZ for Edema Treatment in Patients with Heart Failure...
Soaanz offers an alternative treatment for heart failure patients with edema who skip a loop diuretic dose due to concerns with excessive urination, as well as patients with chronic kidney disease....(PRWeb June 21, 2021)Read the full story at https://www.prweb.com/releases/fda_approves_soaanz_for_edema_treatment_in_patients_with_heart_failure_and_renal_disease/prweb18013131.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - June 21, 2021 Category: Pharmaceuticals Source Type: news

A promising new target for urinary tract infections and kidney stones
(Tokyo Medical and Dental University) Researchers from Tokyo Medical and Dental University (TMDU) have found that the urinary secretion of uromodulin, a kidney-specific protein, can be increased by the hormone vasopressin via certain signaling pathways. Increasing the urinary secretion of uromodulin may protect against urinary tract infections and kidney stones, while the resulting lower uromodulin levels in kidney cells may help to prevent hypertension and chronic kidney disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 17, 2021 Category: International Medicine & Public Health Source Type: news