Metformin Associated with Lower Mortality Risk in Heart Failure, Chronic Kidney Disease (FREE)
By Kelly Young Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD Use of metformin is associated with reduced mortality in patients with diabetes plus chronic heart failure (CHF), chronic kidney disease (CKD), or chronic liver disease, according … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - January 2, 2017 Category: Primary Care Source Type: news

Breast and cervical cancer screening rates are low in women with advanced kidney disease
(American Society of Nephrology) In a recent study, most women with advanced chronic kidney disease had not received breast or cervical cancer screening in recent years. Older age, greater comorbidities, and lower income were associated with a lower rate of screening. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 29, 2016 Category: Global & Universal Source Type: news

Keeping the Resolve in Your New Year's Resolutions
Losing weight is a top New Year's resolution for many Americans. Reaching and staying at a healthy weight are resolutions worth keeping--not just throughout the year, but throughout a lifetime. Avoiding overweight and obesity may help reduce the risk of developing a host of health problems, including diabetes, chronic kidney disease, heart disease, and some types of cancer. With more than 2 in 3 American adults considered overweight or obese, maintaining a healthy weight is a major public health concern. Setting Goals and Creating an Action Plan If you've resolved to lose weight, you're more likely to keep your resoluti...
Source: Healthy Living - The Huffington Post - December 23, 2016 Category: Consumer Health News Source Type: news

HF Risk Outweighs Stroke in Chronic Kidney Disease
(MedPage Today) -- Observed risk particularly high in African Americans and Hispanics (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - December 21, 2016 Category: Urology & Nephrology Source Type: news

​Cambridge’s Akebia announces deal worth $170M now, maybe over $1B later
Cambridge-based Akebia Therapeutics has announced a collaboration and license agreement in the U.S. for its anemia drug with a Japanese drugmaker under which it will get $160 million in coming months and potentially more than $1 billion in coming years. The agreement between Akebia (Nadsaq: AKBA) and Otsuka Pharmaceutical Co. is related to Akebia’s drug, vadadustat, which is now in development for the treatment of anemia associated with chronic kidney disease. Anemia related to CKD affects an… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - December 20, 2016 Category: Pharmaceuticals Authors: Don Seiffert Source Type: news

PCI Without Contrast in Advanced Renal Failure PCI Without Contrast in Advanced Renal Failure
The authors report on a novel strategy for safely performing PCI without the use of contrast in patients with advanced chronic kidney disease.European Heart Journal (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 19, 2016 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

Protein in urine linked to increased risk of memory problems
Chronic kidney disease and dementia share many risk factors, researchers point out Related items fromOnMedica Constipation linked to kidney disease Dementia now leading cause of death in England and Wales Memory clinic referral criteria delay diagnosis 'Watch and wait' might be better in advanced kidney cancer (Source: OnMedica Latest News)
Source: OnMedica Latest News - December 14, 2016 Category: UK Health Source Type: news

Proteon Therapeutics kidney drug fails key study, shares slump
(Reuters) - Proteon Therapeutics Inc said on Tuesday that its experimental chronic kidney disease drug failed to meet the main goal in a late-stage study, sending its shares plunging 70 percent in premarket trading. (Source: Reuters: Health)
Source: Reuters: Health - December 13, 2016 Category: Consumer Health News Tags: healthNews Source Type: news

Cardiovascular complications of renal disease
Aetiology and management of risk factors for cardiovascular disease in patients with chronic kidney disease and the use of beta-blockers, statins, diuretics and anticoagulants in controlling progression of disease. (Source: GP Online Education)
Source: GP Online Education - December 13, 2016 Category: Primary Care Tags: 15.1 Cardiovascular Problems Source Type: news

Bone marrow-derived cells are source of key kidney disease biomarker SuPAR
A protein that is a reliable biomarker for chronic kidney disease originates in the bone marrow, new research suggests. This discovery of where the suPAR protein is an important step towards earlier detection -and possible prevention -- of a disease suffered by one in 10 adults, kills 48,000 people and costs Medicare $49 billion each year (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - December 12, 2016 Category: Science Source Type: news

Major depression and long-term outcomes of acute kidney injury - Balogun RA, Omotoso BA, Xin W, Ma JZ, Scully KW, Arogundade FA, Abdel-Rahman EM.
This study determines the prognostic implication of a diagnosi... (Source: SafetyLit)
Source: SafetyLit - December 10, 2016 Category: Global & Universal Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Healthy Diet May Mean Longer Life for Kidney Patients
Study found eating lots of fruit, vegetables, fish, whole grains was linked to lower rate of early death Source: HealthDay Related MedlinePlus Pages: Chronic Kidney Disease, Nutrition (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - December 9, 2016 Category: Consumer Health News Source Type: news

Healthy Diet May Mean Longer Life for Kidney Patients
THURSDAY, Dec. 8, 2016 -- A healthy diet may help people with kidney disease live longer, researchers report. They analyzed seven studies that included more than 15,000 people with chronic kidney disease, to assess the effects of a diet high in... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - December 8, 2016 Category: Journals (General) Source Type: news

Kidney disease hospitalization and mortality rates continue to decline in the US
(University of Michigan Health System) According to an annual data report from the United States Renal Data System (USRDS), hospitalization and mortality rates for patients with chronic kidney disease continue to decline in the US. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 2, 2016 Category: Global & Universal Source Type: news

Fetal and Neonatal Renal Failure and Renal Transplant
Major advances have been made over the past few decades in caring for neonates with chronic renal disease. Although dialysis registries report infants as a high-risk population for poor outcomes, these children can be effectively maintained on dialysis until they are ready for receiving a transplant. Early identification of the presence of chronic renal disease is helpful in preparing for postnatal complications and to counsel parents on potential outcomes of infants with chronic kidney disease. (Source: NeoReviews recent issues)
Source: NeoReviews recent issues - November 30, 2016 Category: Pediatrics Authors: Wong, C. J. Tags: Pediatric Drug Labeling Update Complex Fetal Care Source Type: news

Assessing Fluid Status and Physical Function in Patients With CKD Assessing Fluid Status and Physical Function in Patients With CKD
Dr Desai discusses new methods of evaluating body composition and physical function in patients with chronic kidney disease who are not on dialysis.Medscape Nephrology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 28, 2016 Category: Consumer Health News Tags: Nephrology Viewpoint Source Type: news

GSK initiates Phase III programme of daprodustat
UK drug manufacturer GlaxoSmithKline (GSK) has initiated its Phase III programme of daprodustat being developed to treat anaemia associated with chronic kidney disease (CKD). (Source: Drug Development Technology)
Source: Drug Development Technology - November 28, 2016 Category: Pharmaceuticals Source Type: news

Baxter touts blood purification efficiency in EBP studies
Baxter (NYSE:BAX) today released data from 2 studies on extracorporeal blood purification studies, touting the blood purification method’s ability to remove harmful molecules linked to inflammation. Extracorporeal blood purification takes place outside the body, with blood passing through a membrane within an extracorporeal circuit to filter harmful molecules and waste products out of the blood, the company said. The clean blood is then returned to the body. The method is commonly used for patients with kidney injuries. Data from the studies was presented at the American Society of Nephrology’s annual Kidn...
Source: Mass Device - November 22, 2016 Category: Medical Equipment Authors: Fink Densford Tags: Blood Management Clinical Trials Baxter Source Type: news

Poor Sleep Linked to Worsening Kidney Disease
SATURDAY, Nov. 19, 2016 -- For people with chronic kidney disease, poor sleep may boost the chances that their illness will worsen, new research suggests. " Short sleep and fragmented sleep are significant yet unappreciated risk factors for chronic... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 19, 2016 Category: Journals (General) Source Type: news

Program Helps With Transition to Renal Replacement Therapy Program Helps With Transition to Renal Replacement Therapy
After completion of a program on the transition from late-stage chronic kidney disease to end-stage renal replacement therapy, patients had a better understanding of their treatment options.Medscape Medical News (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - November 18, 2016 Category: Intensive Care Tags: Nephrology News Source Type: news

Lowering Urate Helps Renal Function
(MedPage Today) -- Most improvement seen in stage 3 chronic kidney disease (Source: MedPage Today Meeting Coverage)
Source: MedPage Today Meeting Coverage - November 18, 2016 Category: Journals (General) Source Type: news

Reflux and ulcer medications linked to kidney stones and chronic kidney disease
Certain medications commonly used to treat heartburn, acid reflux, and ulcers can have damaging effects on the kidneys. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 18, 2016 Category: Science Source Type: news

Smoking may hinder kidney disease drugs
HealthDay News Cigarette smoking may decrease the effectiveness of drugs taken during early stages of chronic kidney disease, a small study suggests. (Source: Health News - UPI.com)
Source: Health News - UPI.com - November 18, 2016 Category: Consumer Health News Source Type: news

Smoking May Hinder Kidney Disease Drugs
FRIDAY, Nov. 18, 2016 -- Cigarette smoking may decrease the effectiveness of drugs taken during early stages of chronic kidney disease, a small study suggests. Blood pressure-lowering drugs known as angiotensin-converting enzyme inhibitors slow... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 18, 2016 Category: Journals (General) Source Type: news

Reducing salt intake may help protect kidney patients ’ heart and kidney health
New research indicates that reducing sodium intake may provide kidney and heart benefits for patients with chronic kidney disease (CKD). (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 18, 2016 Category: Science Source Type: news

Combo Shows Promise for Hep C Patients With Renal Disease Combo Shows Promise for Hep C Patients With Renal Disease
The combination of glecaprevir plus pibrentasvir is effective and safe for people with any genotype of the hepatitis C virus who have moderate to severe chronic kidney disease, new research shows.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - November 17, 2016 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Researchers discover how to prevent calcification of heart tissue
FINDINGSResearchers at the  Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have discovered that calcification of heart muscle tissue is caused when a type of cell called cardiac fibroblasts go awry. The scientists also found that blocking a molecular pathway in cardiac fibroblasts prevents heart calcification in mice.BACKGROUNDIn bones, cells called osteoblasts create a strong, dense matrix out of calcium and phosphate. Calcification of soft tissues — known as ectopic calcification — is abnormal and occurs with common diseases such as diabetes and chronic kidney disease...
Source: UCLA Newsroom: Health Sciences - November 17, 2016 Category: Universities & Medical Training Source Type: news

Researchers identify pathway important for kidney function
(Boston University Medical Center) Boston University researchers, in collaboration with Centers for Therapeutic Innovation at Pfizer Inc., have discovered a novel molecular pathway needed to regulate kidney podocytes -- special octopus-like cells that are critical in maintaining normal kidney function. The findings, which appear in JCI Insight, may help identify a new drug target for chronic kidney diseases associated with podocyte loss. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 17, 2016 Category: Global & Universal Source Type: news

Wayne State and Henry Ford present findings on ESRD and CKD
(Wayne State University - Office of the Vice President for Research) On Nov. 17, 2016, a Wayne State University doctoral student, Matthew Jasinski, will present results from his dissertation at the Annual Meeting of the American Society of Nephrology in Chicago. The study demonstrates the value of proactive identification of and family psychoeducation about cognitive impairment in patients with End-Stage Renal Disease or Chronic Kidney Disease (ESRD/CKD). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 17, 2016 Category: Global & Universal Source Type: news

Pregnancy in Women With CKD: A Success Story Pregnancy in Women With CKD: A Success Story
Pregnancies among women with chronic kidney disease may come with a high risk of complications, but better management practices have improved maternal and fetal outcomes.American Journal of Kidney Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 15, 2016 Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news

Central Sleep Apnea Tied to Faster Decline in Non-Dialyzed CKD Patients Central Sleep Apnea Tied to Faster Decline in Non-Dialyzed CKD Patients
Central sleep apnea (CSA) is associated with an increased mortality risk in patients with chronic kidney disease (CKD) who are not on dialysis, new research shows.Reuters Health Information (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - November 14, 2016 Category: Intensive Care Tags: Family Medicine/Primary Care News Source Type: news

The More Constipated You Get, The Higher Your Risk For Kidney Disease
In what may not make for the sexiest headline, a new study shows there’s a link between constipation and kidney disease. In the study, researchers examined health records from more than 3.5 million U.S. veterans, looking at whether they reported being constipated or had used laxatives over period of about seven years. They found that those who had experienced constipation had higher risks of developing chronic kidney disease and kidney failure than those who had not. They also found that the more severe the participant’s constipation, the higher their risk of developing these kidney conditions. “We cannot...
Source: Science - The Huffington Post - November 14, 2016 Category: Science Source Type: news

Allopurinol does not increase chronic kidney disease risk in gout patients
(American College of Rheumatology) Allopurinol, a widely used treatment for lowering serum urate levels, does not appear to increase risk of kidney deterioration in gout patients with normal or near-normal kidney function, according to new research findings presented this week at the 2016 ACR/ARHP Annual Meeting in Washington. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 12, 2016 Category: Global & Universal Source Type: news

European Commission Approves Parsabiv ™ (etelcalcetide) For The Treatment Of Secondary Hyperparathyroidism In Adults On Hemodialysis
First Treatment Advance for Secondary Hyperparathyroidism in More Than a Decade and First Intravenous Calcimimetic to Help Healthcare Providers Lower Key Lab Values THOUSAND OAKS, Calif., Nov. 11, 2016 /PRNewswire/ -- Amgen (NASDAQ:AMGN) today announced that the European Commission (EC) has granted marketing authorization for Parsabiv™ (etelcalcetide) for the treatment of secondary hyperparathyroidism (sHPT) in adult patients with chronic kidney disease (CKD) on hemodialysis. Parsabiv is the first calcimimetic agent that can be administered intravenously by a healthcare provider three times a week at the en...
Source: Amgen News Release - November 11, 2016 Category: Pharmaceuticals Tags: Uncategorized Source Type: news

Link between constipation, kidney disease uncovered
Individuals with constipation had a 13% higher likelihood of developing chronic kidney disease and a 9% higher likelihood of developing kidney failure compared with individuals without constipation, report investigators. More severe constipation was linked with an incrementally higher risk for both chronic kidney disease and kidney failure. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 11, 2016 Category: Science Source Type: news

Constipation linked to kidney disease
Constipation linked to 13% higher risk of chronic kidney disease and 9% higher risk of kidney failure Related items fromOnMedica AF associated with more comorbidities than had been thought Guidance hopes to speed up diagnosis of kidney disease Diet for lowering blood pressure also reduces risk of kidney disease Constipation in infants and children (Source: OnMedica Latest News)
Source: OnMedica Latest News - November 10, 2016 Category: UK Health Source Type: news

Suicide and chronic kidney disease: a case-control study - Liu CH, Yeh MK, Weng SC, Bai MY, Chang JC.
The objectives of this study were to assess the association of suicide with CKD and dialysis and investigate whether differences exist between di... (Source: SafetyLit)
Source: SafetyLit - November 9, 2016 Category: Global & Universal Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Study links first kidney stone event with chronic kidney disease
Ryan MaassROCHESTER, Minn., Nov. 2 (UPI) -- A study of first-time kidney stone formers found subsequent abnormal kidney function connected to higher risk for chronic kidney disease. (Source: Health News - UPI.com)
Source: Health News - UPI.com - November 2, 2016 Category: Consumer Health News Source Type: news

Research connects first-time kidney stone formers and chronic kidney disease
(Mayo Clinic) Mayo Clinic nephrologists have uncovered a connection between first-time kidney stone formers and chronic kidney disease. In a paper published today in Mayo Clinic Proceedings, researchers announce a persistent decline in kidney functioning following an individual's first case of kidney stones. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 2, 2016 Category: Global & Universal Source Type: news

Research connects first-time kidney stone formers and chronic kidney disease
ROCHESTER, Minn. ? Mayo Clinic nephrologists have uncovered a connection between first-time kidney stone formers and chronic kidney disease. In a paper published today in Mayo Clinic Proceedings, researchers announce a persistent decline in kidney functioning following an individual?s first case of kidney stones. A Mayo Clinic team led by William Haley, M.D., and Andrew [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - November 1, 2016 Category: Research Source Type: news

Improve Kidney Function With IV Laser Treatment
If you're one of the more than 20 million Americans who suffer from chronic kidney disease (CKD), your doctor has probably told you there isn't much they can do for you. Mainstream medicine doesn't have a cure for CKD. What they do have is a lot of drugs to treat the symptoms of it. And most of the drugs will leave you worse off than before you started taking them… Like ESAs, which are prescribed to treat anemia caused by chronic kidney disease. These dangerous drugs can cause strokes, heart attacks, blood clots and seizures. And if your kidneys fail, your only options are dialysis or a kidney transplant...
Source: Al Sears, MD Natural Remedies - October 31, 2016 Category: Complementary Medicine Authors: Cathy Card Tags: Anti-Aging Source Type: news

How NxStage is changing the game: A conversation with founder & CEO Jeff Burbank
NxStage Medical (NSDQ:NXTM) was founded in 1999 on the premise that patients with chronic kidney disease would benefit from bringing hemodialysis out of the clinic and into their homes. Seventeen years later, NxStage founder & CEO Jeff Burbank’s hypothesis has proven out. His Lawrence, Mass.-based company is topping more than $300 million in annual sales and, more importantly, is making a real difference in the everyday lives of dialysis patients. NxStage took on some of the biggest names in medtech along the way and managed to beat them back, as evidenced by Baxter‘s (NYSE:BAX) dec...
Source: Mass Device - October 5, 2016 Category: Medical Equipment Authors: Brian Johnson Tags: Device Talks Podcasts Dialysis Drug-Device Combinations NxStage Medical Inc. Source Type: news

New Data on Empagliflozin in Treating Diabetic Kidney Disease New Data on Empagliflozin in Treating Diabetic Kidney Disease
Dr Desai discusses a new study exploring the long-term renal effects of empagliflozin and whether it could protect kidney function in patients with diabetes and chronic kidney disease.Medscape Nephrology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 29, 2016 Category: Consumer Health News Tags: Nephrology Viewpoint Source Type: news

Dialysis used more often in U.S. than other developed nations
Stephen FellerWASHINGTON, Sept. 23 (UPI) -- Compared to other developed countries, a significantly higher portion of chronic kidney disease patients in the U.S. received dialysis, according to a study. (Source: Health News - UPI.com)
Source: Health News - UPI.com - September 23, 2016 Category: Consumer Health News Source Type: news

Deals this week: Bayer AG, Plasticell, Sarepta Therapeutics
Bayer AG and Evotec AG have entered a multi-target research partnership agreement to develop novel treatments for chronic kidney disease in diabetic patients. (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - September 22, 2016 Category: Pharmaceuticals Source Type: news

Progression to End-Stage Kidney Disease Unlikely in Primary Care Patients with Moderate CKD (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM Adults with moderate chronic kidney disease (CKD) are unlikely to progress to end-stage renal disease over a 5-year period, according … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - September 20, 2016 Category: Primary Care Source Type: news

Controlling Phosphorus in Chronic Kidney Disease Controlling Phosphorus in Chronic Kidney Disease
Controlling serum phosphorus in chronic kidney disease has proved challenging, but doing so improves clinical outcomes among these patients.Nephrology Dialysis Transplantation (Source: Medscape Orthopaedics Headlines)
Source: Medscape Orthopaedics Headlines - September 15, 2016 Category: Orthopaedics Tags: Nephrology Journal Article Source Type: news

Kidney Disease Common Five Years After Congenital Cardiac Surgery Kidney Disease Common Five Years After Congenital Cardiac Surgery
Five years after surgery for congenital heart defects, many children have hypertension and chronic kidney disease (CKD), new research shows.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - September 13, 2016 Category: Surgery Tags: Pediatrics News Source Type: news

Irregular heartbeat may be tied to more than just stroke risk
(Reuters) – Atrial fibrillation, a type of irregular heartbeat that’s already linked to an increased risk of stroke, may also be tied to higher risk of heart attack, heart failure, kidney disease and sudden death, according to a new research review. “It was particularly noteworthy that the relative and absolute risk increase for heart failure was the highest among all outcomes examined, even higher than the risk of stroke, said lead author Ayodele Odutayo, a doctoral candidate at the University of Oxford in the U.K. In atrial fibrillation, the upper chambers of the heart flutter or beat irregularly. Somet...
Source: Mass Device - September 8, 2016 Category: Medical Equipment Authors: MassDevice Tags: Cardiovascular American Heart Assn. Source Type: news

Scientists find culprit responsible for calcified blood vessels in kidney disease
Scientists have implicated a type of stem cell in the calcification of blood vessels that is common in patients with chronic kidney disease. The research will guide future studies into ways to block minerals from building up inside blood vessels and exacerbating atherosclerosis, the hardening of the arteries. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 8, 2016 Category: Science Source Type: news