Proton Pump Inhibitors May Increase Risk for Kidney Disease Proton Pump Inhibitors May Increase Risk for Kidney Disease
Proton pump inhibitors such as omeprazole are linked to increased risks for chronic kidney disease and for acute kidney injury, according to two population-based analyses. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 11, 2016 Category: Consumer Health News Tags: Internal Medicine News Source Type: news

PPIs Tied to Increased Risk for Chronic Kidney Disease (CME/CE)
(MedPage Today) -- Whether drugs actually cause CKD remains uncertain (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - January 11, 2016 Category: Urology & Nephrology Source Type: news

Heartburn Meds Linked to Chronic Kidney Disease
While study can't prove cause-and-effect, increasing damage seen as dose rises (Source: WebMD Health)
Source: WebMD Health - January 11, 2016 Category: Consumer Health News Source Type: news

Heartburn Meds Linked to Chronic Kidney Disease
While study can't prove cause-and-effect, increasing damage seen as dose rises Source: HealthDay Related MedlinePlus Pages: Drug Reactions, Heartburn, Kidney Diseases (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - January 11, 2016 Category: Consumer Health News Source Type: news

Kidney injury common following vascular surgery
Both acute kidney injury and chronic kidney disease were common in patients undergoing major vascular surgical procedures and were associated with an increase in long-term cardiovascular-specific death compared with patients with no kidney disease, according to a study. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - December 23, 2015 Category: Science Source Type: news

The Isolation and Quantitation of Fetuin-A-Containing Calciprotein Particles from Biological Fluids
Multiple overlapping systemic and local inhibitory networks have evolved to prevent the unwanted deposition of mineral at ectopic sites. Fetuin-A is a liver-derived glycoprotein abundant in plasma that binds and stabilizes nascent mineral ion nuclei to form soluble colloidal high molecular weight complexes, called calciprotein particles (CPP). The binding of fetuin-A to mineral retards crystal ripening and precipitation from the aqueous phase, thereby facilitating the regulated clearance of mineral debris from the extracellular fluid. However, persistent disturbances in this humoral homeostatic system, as frequently seen i...
Source: Springer protocols feed by Molecular Medicine - December 22, 2015 Category: Molecular Biology Source Type: news

Vascular Calcification in Uremia: New-Age Concepts about an Old-Age Problem
A hallmark of aging, and major contributor to the increased prevalence of cardiovascular disease in patients with chronic kidney disease (CKD), is the progressive structural and functional deterioration of the arteries and concomitant accrual of mineral. Vascular calcification (VC) was long viewed as a degenerative age-related pathology that resulted from the passive deposition of mineral in the extracellular matrix; however, since the discovery of “bone-related” protein expression in calcified atherosclerotic plaques over 20 years ago, a plethora of studies have evoked the now widely accepted view that VC is a...
Source: Springer protocols feed by Molecular Medicine - December 22, 2015 Category: Molecular Biology Source Type: news

Prolonged and Continuous Measurement of Kidney Oxygenation in Conscious Rats
A relative deficiency in kidney oxygenation, i.e., renal hypoxia, may contribute to the initiation and progression of acute and chronic kidney disease. A critical barrier to investigate this is the lack of methods allowing measurement of the partial pressure of oxygen in kidney tissue for long periods in vivo. We have developed, validated, and tested a novel telemetric method that can do this. Here we provide details on the calibration, implantation, implementation for data recording, and reuse of this telemetry-based technology for measurement of medullary tissue oxygen tension in conscious, unrestrained rats. This techni...
Source: Springer protocols feed by Molecular Medicine - December 22, 2015 Category: Molecular Biology Source Type: news

Kidney-Disease Patients With Dietary Protein From PlantsKidney-Disease Patients With Dietary Protein From Plants
Eating a higher proportion of protein from plant sources like soy, nuts and legumes, rather than animal sources, is tied to reduced mortality risk in people with chronic kidney disease (CKD), according to new research. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 21, 2015 Category: Consumer Health News Tags: Nephrology News Source Type: news

Akebia and Mitsubishi to develop and commercialise CKD drug vadadustat in Asia
US-based Akebia Therapeutics has entered into a development and commercialisation agreement with Mitsubishi Tanabe Pharma (MTPC) for vadadustat (formerly AKB-6548), an oral therapy that treats anaemia related to chronic kidney disease (CKD) in Japan … (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - December 15, 2015 Category: Pharmaceuticals Source Type: news

Ambulatory and Home Blood Pressure Monitoring in People With CKDAmbulatory and Home Blood Pressure Monitoring in People With CKD
How important is out of office BP data for patients with chronic kidney disease? Current Opinion in Nephrology and Hypertension (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 11, 2015 Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news

Thyroid Dysfunction and Dyslipidemia in CKD PatientsThyroid Dysfunction and Dyslipidemia in CKD Patients
Find out more about the prevalence of thyroid and lipid disorders in patients with chronic kidney disease -- and how these complications may contribute to the risk for cardiovascular disease. BMC Endocrine Disorders (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 8, 2015 Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news

Study reveals non-invasive warning sign of kidney disease progression
Researchers have identified an accessible, non-invasive way to identify patients at risk for progression of kidney disease. Chronic kidney disease is a condition in which damaged kidneys cannot filter blood as well as healthy kidneys. Currently, it is estimated that over 10 million individuals suffer from chronic kidney disease, with the number of those affected continuing to rise. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - December 3, 2015 Category: Science Source Type: news

Biomarkers of Rapid CKD Progression in Type 2 DiabetesBiomarkers of Rapid CKD Progression in Type 2 Diabetes
Which biomarkers show rapid progression of chronic kidney disease in patients with type 2 diabetes? Kidney International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 27, 2015 Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news

Blood phosphorus levels can help predict kidney failure risk in African Americans
An increase in serum phosphorus levels in African Americans with chronic kidney disease (CKD) is associated with faster progression to kidney failure, known as end-stage renal disease (ESRD). The study confirmed in African Americans what previous studies in Caucasians demonstrated, that an increase in the biomarker predicted ESRD risk. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 17, 2015 Category: Science Source Type: news

Blood phosphorus levels can help predict kidney failure risk in African-Americans
(American Society of Nephrology) An increase in serum phosphorus levels in African-Americans with chronic kidney disease is associated with faster progression to kidney failure, known as end-stage renal disease (ESRD). The study confirmed in African-Americans what previous studies in Caucasians demonstrated, that an increase in the biomarker predicted ESRD risk. The research, from the Indiana University School of Medicine, was presented at ASN Kidney Week 2015 Nov. 3-8 at the San Diego Convention Center in San Diego, CA. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 17, 2015 Category: Global & Universal Source Type: news

Is 120 mm Hg the new BP target? What headlines aren’t telling you
The results of the SPRINT trial are in, and you’ve probably heard that making 120 mm Hg the new blood pressure target helped lower mortality rates. Yet the study outcomes apply only to a specific subset of patients with hypertension. See whether or not your patients may fit into this category. In the much-anticipated results of the SPRINT trial, the relative risk of death from cardiovascular causes was 43 percent lower for patients receiving more intensive treatment for a 120 mm Hg target versus those who received standard treatment for a 140 mm Hg target. While these results were unexpected and are noteworthy...
Source: AMA Wire - November 11, 2015 Category: Journals (General) Authors: amamod Source Type: news

Penn researchers present findings on cardiac risks for patients with chronic kidney disease
(University of Pennsylvania School of Medicine) Chronic Kidney Disease (CKD), which afflicts more than 26 million Americans, is a condition in which individuals experience a slow loss of kidney function over time. At the American Heart Association Scientific Sessions 2015, researchers from the Perelman School of Medicine at the University of Pennsylvania today presented findings from their analysis of the Chronic Renal Insufficiency Cohort study to evaluate risk markers for adverse cardiac events in patients with CKD. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 10, 2015 Category: Global & Universal Source Type: news

Penn researchers present findings on cardiac risks for patients with chronic kidney disease
(University of Pennsylvania School of Medicine) Chronic kidney disease (CKD), which afflicts more than 26 million Americans, is a condition in which individuals experience a slow loss of kidney function over time. At the American Heart Association Scientific Sessions 2015, researchers from the Perelman School of Medicine at the University of Pennsylvania will present findings from their analysis of the chronic renal insufficiently cohort study to evaluate risk markers for adverse cardiac events in patients with CKD. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 8, 2015 Category: Global & Universal Source Type: news

Gut microbiota changes in diabetic kidney disease contribute to chronic inflammation and vascular complications
Among patients with type 2 diabetes and advanced chronic kidney disease (CKD), a shift in gut microbiota diversity in combination with elevated plasma zonulin levels substantially impacts the degree of chronic inflammation and endothelial dysfunction. Zonulin could be a potential future target to control inflammatory immune responses, according to a new study. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 6, 2015 Category: Science Source Type: news

Blood test can predict kidney disease 5 years before damage starts
Stephen FellerCHICAGO, Nov. 6 (UPI) -- Testing blood for soluble urokinase-type plasminogen activator receptor can predict risk for developing chronic kidney disease 5 years before it causes harm. (Source: Health News - UPI.com)
Source: Health News - UPI.com - November 6, 2015 Category: Consumer Health News Source Type: news

Early warning found for chronic kidney disease
A simple blood test for the suPAR protein can predict a person's chances of developing chronic kidney disease five years before symptoms emerge, thus doing for kidney disease what cholesterol has done for cardiovascular disease, new research shows. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 5, 2015 Category: Science Source Type: news

Early Warning Sign for Kidney Disease Identified in Study
Researchers say blood test can predict risk up to five years before damage begins Source: HealthDay Related MedlinePlus Pages: Chronic Kidney Disease, Laboratory Tests (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - November 5, 2015 Category: Consumer Health News Source Type: news

When Initiating Dialysis, Can eGFR Stand Alone?When Initiating Dialysis, Can eGFR Stand Alone?
New Japanese guidelines raise questions about whether creatinine levels are sufficient to determine the need for dialysis in chronic kidney disease, says Dr Jeffrey Berns. Medscape Nephrology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 28, 2015 Category: Consumer Health News Tags: Nephrology Commentary Source Type: news

NICE approves new drug for chronic kidney disease
For the first time, a treatment will be available on the NHS in England and Wales that can delay the development of autosomal dominant polycystic kidney disease (ADPKD). (Source: Nursing Times Breaking News)
Source: Nursing Times Breaking News - October 28, 2015 Category: Nursing Source Type: news

Chronic Heartburn Drugs Tied to Higher Risk of Kidney Disease
But studies weren't designed to prove proton pump inhibitors are responsible for the increase Source: HealthDay Related MedlinePlus Pages: Chronic Kidney Disease, Heartburn (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - October 27, 2015 Category: Consumer Health News Source Type: news

Revascularization in Patients With Multivessel CAD and CKDRevascularization in Patients With Multivessel CAD and CKD
Find out more about the treatment paradox for patients with chronic kidney disease who need coronary revascularization. Journal of the American College of Cardiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 26, 2015 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

DR ELLIE CANNON: I'm losing sleep over back ache  
The Mail on Sunday's GP answers readers' questions on ankylosing spondylitis and chronic kidney disease, and praises Oprah Winfrey for her decision to use WeightWatchers. (Source: the Mail online | Health)
Source: the Mail online | Health - October 26, 2015 Category: Consumer Health News Source Type: news

Kidney Patients without Online Access Face Additional Burden
Blacks and the poor are often 'left behind,' researcher says Source: HealthDay Related MedlinePlus Pages: Chronic Kidney Disease, Health Disparities (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - October 22, 2015 Category: Consumer Health News Source Type: news

Peninsula biotech eyes drug launch after winning FDA approval
Relypsa Inc. won its first drug approval Wednesday as the Food and Drug Administration approved its treatment for potentially fatal levels of potassium in chronic kidney disease patients. The drug, for which the Redwood City company (NASDAQ: RLYP) hadn't announced a price as of late Wednesday afternoon, will carry a "boxed warning" because it could cause other oral drugs to be less effective. A Relypsa spokesman said the company would discuss pricing on a conference call Thursday morning. Pricing… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - October 22, 2015 Category: Biotechnology Authors: Ron Leuty Source Type: news

Investigators create complex kidney structures from human stem cells derived from adults
A highly efficient method has been developed for making kidney structures from stem cells that are derived from skin taken from patients. The kidney structures formed could be used to study abnormalities of kidney development, chronic kidney disease, the effects of toxic drugs, and be incorporated into bioengineered devices to treat patients with acute and chronic kidney injury, say scientists. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - October 17, 2015 Category: Science Source Type: news

A Mysterious Epidemic Plaguing Central America May Be Linked To Climate Change
A mysterious disease has been sweeping through the sugar cane fields of Central America, with more than 20,000 laborers dying from it over the past decade. As of 2012, it had killed the husbands of more than 100 women of the 250 families living on one island in Nicaragua, giving rise to the grim nickname “Island of the Widows.” “Chronic Kidney Disease of nontraditional causes,” as researchers have called the condition, attacks the kidneys and prevents the body from eliminating waste and excess fluid. As the name suggests, no one really knows what causes it. A new report, however, shows&nbs...
Source: Science - The Huffington Post - October 16, 2015 Category: Science Source Type: news

Investigators create complex kidney structures from human stem cells derived from adults
(Brigham and Women's Hospital) Investigators at Brigham and Women's Hospital and the Harvard Stem Cell Institute have established a highly efficient method for making kidney structures from stem cells that are derived from skin taken from patients. The kidney structures formed could be used to study abnormalities of kidney development, chronic kidney disease, the effects of toxic drugs, and be incorporated into bioengineered devices to treat patients with acute and chronic kidney injury. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 16, 2015 Category: Global & Universal Source Type: news

CKD Guideline Implementation in Primary CareCKD Guideline Implementation in Primary Care
Are primary care physicians appropriately following guidelines to identify and manage early stage chronic kidney disease? What are the key barriers to guideline implementation? Journal of the American Board of Family Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 15, 2015 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

Osprey rises on FDA 510(k) for DyeVert
Osprey Medical (ASX:OSP) said it received FDA 510(k) clearance for its DyeVert contrast modulation system, sending shares of the company to a nearly 2-month high. The DyeVert system automates contrast modulation during manual dye injections, self adjusting for catheter and contrast types without requiring user adjustments, Osprey said. “With FDA Clearance of our DyeVert System, we will now gain real-world physician use to gauge market acceptance of the product’s additional automation and ease-of-use benefits,” CEO Mike McCormick said in a press release. A trial of the DyeVert system is underway in Austral...
Source: Mass Device - October 12, 2015 Category: Medical Equipment Authors: Fink Densford Tags: 510(k) Catheters Food & Drug Administration (FDA) Regulatory/Compliance Vascular Osprey Medical Source Type: news

Results from Merck’s Phase 3 Study of Investigational Chronic Hepatitis C Therapy Elbasvir/Grazoprevir in Patients with Advanced Chronic Kidney Disease Published in The Lancet
Dateline City: KENILWORTH, N.J. KENILWORTH, N.J.--(BUSINESS WIRE)--Merck (NYSE:MRK), known as MSD outside the United States and Canada, today announced the publication of results from C-SURFER, the first Phase 31 clinical trial to investigate an all-oral, ribavirin-free chronic hepatitis C virus (HCV) treatment regimen in treatment-naïve and treatment-experienced patients with advanced chronic kidney disease (CKD) stages 4 or 5 and chronic HCV genotype 1 (GT1) infection. Language: English Contact: ...
Source: Merck.com - Research and Development News - October 5, 2015 Category: Pharmaceuticals Tags: Hepatitis C Newsroom Research and Development News Corporate News Latest News Source Type: news

5 Things Your Pet Insurance Policy Should Cover
Currently, there are over a dozen companies in the U.S. and Canada offering pet insurance, and if you've tried sorting out the differences between them, like many pet owners, you probably wound up more confused than when you started. As is the case with insurance of any kind, pet health care coverage is a wonderful thing to have if you need it -- and providing there are no big surprises when you submit a claim for reimbursement. Here's the scenario you want to avoid: You faithfully pay your monthly premium for years and enjoy peace of mind knowing your pet's health care will be paid for in the event of an expensive illne...
Source: Healthy Living - The Huffington Post - September 30, 2015 Category: Consumer Health News Source Type: news

The Epigenetics of Acute and Chronic Kidney DiseaseThe Epigenetics of Acute and Chronic Kidney Disease
This new article discusses the emerging field of epigenetic therapy, and the evolving role that it could play in the future treatment of renal disease. Kidney International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 28, 2015 Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news

How Low Can You Go?
Though Chubby Checker recorded these lyrics to Limbo Rock in 1962, the popular catchphrase still holds true today--especially when it comes to your blood pressure. Ever since 1967, we've been aiming to go low. That is the year the first Veterans Administration Cooperative Trial was published, which confirmed that treatment of patients with high blood pressure resulted in fewer strokes, deaths and cardiovascular complications. Before this landmark study, high blood pressure was not recognized as a disease requiring treatment. There were even physicians who felt that high blood pressure was a phenomenon of aging and that hi...
Source: Healthy Living - The Huffington Post - September 22, 2015 Category: Consumer Health News Source Type: news

Everolimus-Stent PCI Effective in Most CKD Patients: AnalysisEverolimus-Stent PCI Effective in Most CKD Patients: Analysis
PCI wth modern stents seemed an effective alternative to CABG, which guidelines favor in patients with chronic kidney disease; the analysis also provides hints about subgroups that might do better with surgery. Heartwire from Medscape (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - September 18, 2015 Category: Cardiology Tags: Cardiology News Source Type: news

High dietary sodium, potassium may worsen chronic kidney disease
High dietary intake of sodium and potassium may speed the progression of kidney disease, according to a new study. Researchers found that high urinary excretion levels of both sodium and potassium were linked with faster progression of chronic kidney disease. Additionally, they noted that patients with chronic kidney disease tend to consume sodium above the recommended daily limit. An estimated 26 million people in the United States have chronic kidney disease. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 18, 2015 Category: Science Source Type: news

A High Salt and Potassium Diet May Accelerate Chronic Kidney Disease
Study participants had far more sodium than the recommended daily limit (Source: WebMD Health)
Source: WebMD Health - September 17, 2015 Category: Consumer Health News Source Type: news

A High Salt and Potassium Diet May Accelerate Chronic Kidney Disease
Study participants had far more sodium than the recommended daily limit Source: HealthDay Related MedlinePlus Pages: Chronic Kidney Disease, Potassium, Sodium (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - September 17, 2015 Category: Consumer Health News Source Type: news

The New Old Age: Chronic Kidney Disease Can Be Dubious Diagnosis
The condition is so common in older patients that some experts wonder whether it should be considered a disease. (Source: NYT Health)
Source: NYT Health - September 14, 2015 Category: Consumer Health News Authors: PAULA SPAN Tags: Dialysis Elderly Medicine and Health Kidneys Source Type: news

​Amgen files for FDA approval for drug to treat dialysis patients
Amgen Inc. said it has filed for approval to sell its drug to treat patients with chronic kidney disease on dialysis. Thousand Oaks-based Amgen(Nasdaq: AMGN) said it submitted a new drug application to the U.S. Food and Drug Administration for etelcalcetide, formerly AMG 416, for the treatment of secondary hyperparathyroidism, a condition that can cause fragile bones, bone pain and organ damage. If approved, etelcalcetide will be the first calcimimetic agent that can be administered intravenously… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - August 26, 2015 Category: American Health Source Type: news

7 Tips for Traveling With a Parent on Dialysis
Today, kidney disease is the 9th leading cause of death in the United States. About 23 million Americans currently suffer from chronic kidney disease, and nearly 400,000 of them need dialysis. Most use hemodialysis, a procedure that can be done either at home or in a specialized facility and requires the patient to be connected to a large machine for hours at a time, several days a week. If your parent uses hemodialysis, you may think that such a treatment regimen means that his or her traveling days are done. But that doesn't have to be the case! With a little bit of planning, it's quite possible for your parent to travel...
Source: Healthy Living - The Huffington Post - August 14, 2015 Category: Consumer Health News Source Type: news

Proteon begins second Phase III trial of vonapanitase for CKD
Proteon Therapeutics has enrolled first patient in the second Phase III clinical study of its investigational product candidate vonapanitase (formerly PRT-201) for chronic kidney disease (CKD). (Source: Drug Development Technology)
Source: Drug Development Technology - August 12, 2015 Category: Pharmaceuticals Source Type: news

Jade Fowles who donated kidney to save critically ill partner's life marries him
Jade Crawford, 28, married Ben Fowles, 30, from Birmingham, 15 months after she was found to be a perfect match as a donor when he was diagnosed with chronic kidney disease. (Source: the Mail online | Health)
Source: the Mail online | Health - August 12, 2015 Category: Consumer Health News Source Type: news

Woman who donated a kidney to save her critically ill partner's life marries him in fairy tale wedding
Jade Crawford, 28, married Ben Fowles, 30, from Birmingham, 15 months after she was found to be a perfect match as a donor when he was diagnosed with chronic kidney disease. (Source: the Mail online | Health)
Source: the Mail online | Health - August 11, 2015 Category: Consumer Health News Source Type: news

Pair of deals moves Peninsula biotech closer to drug starting line
Relypsa Inc. inked a key drug-selling deal as it moved closer to regulatory approval of a new drug aimed at helping chronic kidney disease patients clear potentially fatal levels of potassium. The fast-growing Redwood City company (NASDAQ: RLYP) said Monday that it would pay Sanofi up to $10 million a year during the launch patiromer in the United States, if the Food and Drug Administration approves the drug in October. The company also said it signed a deal with Vifor Fresenius Medical Care Renal… (Source: bizjournals.com Health Care:Hospitals headlines)
Source: bizjournals.com Health Care:Hospitals headlines - August 11, 2015 Category: Hospital Management Authors: Ron Leuty Source Type: news