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Unlocking the kidney riddle in newborns
Researchers are closer to understanding why babies born with smaller kidneys have a high risk of developing cardiovascular disease. Currently, renal disorders at birth affect about one in 500 babies. Many of these babies go on to lead healthy normal lives, however 20-40 per cent will develop chronic kidney disease and high blood pressure. Unfortunately, these conditions are the main cause of end-stage kidney disease and the need for dialysis in children. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 27, 2015 Category: Science Source Type: news

FDA approves Rockwell Medical's iron replacement drug
(Reuters) - The Food and Drug Administration approved Rockwell Medical Inc's drug for treating iron loss in chronic kidney disease patients on dialysis, sending the company's shares up about 15 percent in premarket trading. (Source: Reuters: Health)
Source: Reuters: Health - January 26, 2015 Category: Consumer Health News Tags: healthNews Source Type: news

Herbs and hazards: risk of Aristolochic acid nephropathy in Iran - Ardalan MR, Khodaie L, Nasri H, Jouyban A.
Herbs are usually considered as inherently harmless products. Nonetheless, various renal injuries have been reported in association with several herbs. The best-known herb-induced chronic kidney disease is aristolochic acid nephropathy. Aristolochic acid i... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - January 24, 2015 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Revolutionary device found to lower blood pressure
A revolutionary device has been shown to significantly lower blood pressure among patients with uncontrolled high blood pressure, compared to those treated with usual drug measures. "High blood pressure is very dangerous and leads to hospital treatment, stroke, heart attack and chronic kidney disease. We must find better means of treating high blood pressure as drugs do not work for everyone and the Coupler is a big step forward in our search for alternative treatment," said the lead investigator. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 23, 2015 Category: Science Source Type: news

Once-daily treatment option for people with type 2 diabetes and moderate CKD in the UK
Moderate chronic kidney disease affects up to 40% of all people with type 2 diabetes in the UK, which is approximately one million people (1,2). Type 2 diabetes costs the NHS a total of £21.8 billion in 2010/2011, with the complications of chronic kidney disease accounting for an estimated £753.8 million. These figures are predicted to rise to £35.6 billion for type 2 diabetes and £1.3 billion for kidney disease in people with type 2 diabetes by 2035/36 (3). The licence extension for Victoza® (liraglutide) increases clinicians’ prescribing options to help patients with both conditions achi...
Source: Pharmacy Europe - January 20, 2015 Category: Drugs & Pharmacology Authors: Annabel De Coster Tags: *** Editor's Pick Practical therapeutics Industry News Diabetes Endochrine Disorders Nephrology Patient care glucose control kidney disease Latest News liraglutide renal impairment type 2 diabetes victoza Source Type: news

Tool helps measure patients' readiness to make decisions about starting dialysis
A new algorithm is a useful tool for measuring chronic kidney disease patients' readiness for making decisions about initiating dialysis. Patients who have knowledge about their options and have fewer lifestyle barriers to home dialysis are more likely to be ready to make decisions. Doctors who explain all of the treatment options that are available can increase patients' readiness for decision-making, say authors of a new study. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 16, 2015 Category: Science Source Type: news

AKC Canine Health Foundation and Zoetis Award Grants for Chronic...
The AKC Canine Health Foundation (CHF), in partnership with Zoetis Inc., announce the funding of two grants that will help accelerate novel, emerging technology in canine chronic kidney disease and...(PRWeb January 14, 2015)Read the full story at http://www.prweb.com/releases/2015/01/prweb12444439.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - January 15, 2015 Category: Pharmaceuticals Source Type: news

Feds Could Change The Way We View Sugar, Salt And Meat
WASHINGTON (AP) — For years, the government has told Americans to eat their vegetables. A rewrite of the government's dietary guidelines could include some new advice, too, on sugar, salt, meat and caffeine. Whether individuals listen or not, the dietary guidelines affect nutritional patterns throughout the country — from federally subsidized school lunches to labels on food packages to your doctor's advice. They also form the basis for the government's "My Plate" icon, which replaced the food pyramid a few years ago. A government advisory committee made up of medical and nutrition exper...
Source: Science - The Huffington Post - January 8, 2015 Category: Science Source Type: news

Kidney Disease Treatment May Be Improving, Study Suggests
Even though rate of disease is on the rise, fewer patients are suffering organ failure or dying Source: HealthDay Related MedlinePlus Pages: Chronic Kidney Disease, Kidney Diseases, Kidney Failure (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - January 8, 2015 Category: Consumer Health News Source Type: news

Potential option for treating chronic kidney disease
New clinical research indicates the drug tetrahydrobiopterin may be able to dial back over-activation of the sympathetic nervous system in chronic kidney disease. New clinical research indicates the drug tetrahydrobiopterin may be able to dial back this overactivation, leading to positive effects on the sympathetic nervous system and some measures of arterial stiffness. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 6, 2015 Category: Science Source Type: news

Small change in blood acidity could prove detrimental to kidney disease patients
Very small changes in the level of acidity in blood may have a detrimental impact on the health of patients with kidney disease, a scientist has discovered. The research focussed on the high level of parathyroid hormone (PTH) in patients suffering from chronic kidney disease. This causes the body to release calcium and phosphate from the bones which can then damage their blood vessels. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 6, 2015 Category: Science Source Type: news

Potential option for treating chronic kidney disease
(Emory Health Sciences) New clinical research indicates the drug tetrahydrobiopterin may be able to dial back over-activation of the sympathetic nervous system in chronic kidney disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 6, 2015 Category: Global & Universal Source Type: news

Hyperphosphataemia in chronic kidney disease
See a summary of selected new evidence relevant to NICE clinical guideline 157 ‘Management of hyperphosphataemia in patients with stage 4 or 5 chronic kidney disease’ (2013). (Source: NHS Networks)
Source: NHS Networks - December 23, 2014 Category: UK Health Authors: Maria Axford Source Type: news

National trial first to focus on long-term complications associated with chronic kidney disease, diabetes, hypertension
UT Southwestern will lead the first National Institutes of Health-funded, multicenter, clinical trial to address interventions for patients with multiple chronic conditions centered around kidney disease. (Source: UT Southwestern Medical Center News)
Source: UT Southwestern Medical Center News - December 20, 2014 Category: Hospital Management Source Type: news

National trial first to focus on long-term complications associated with chronic kidney disease
(UT Southwestern Medical Center) UT Southwestern will lead the first National Institutes of Health-funded, multicenter, clinical trial to address interventions for patients with multiple chronic conditions centered around kidney disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 19, 2014 Category: Global & Universal Source Type: news

Less Advanced Chronic Kidney Disease and Outcomes After Total Hip and Knee Arthroplasty
Source: Lippincott’s Bone and Joint Newsletter - December 17, 2014 Category: Orthopaedics Tags: CME Article Source Type: news

Chronic kidney disease management
Key learning points: - Who is most at risk of developing chronic kidney disease - Detecting chronic kidney disease - Long-term monitoring and referral for specialist assessment Hide related content:  Show related content Featured In Issue:  Nursing in Practice | 81 read more (Source: Nursing in Practice)
Source: Nursing in Practice - December 12, 2014 Category: Nursing Authors: Lucinda Borrell Tags: Alcohol and drugs Smoking cessation Family health Source Type: news

Simple model predicts progression of kidney disease among socially disadvantaged patients
A simple model using 5 commonly available variables from electronic health records adequately discriminates between socially disadvantaged individuals with chronic kidney disease who will and will not progress to kidney failure. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - December 5, 2014 Category: Science Source Type: news

Low levels of circulating protein linked with heart problems in mice with kidney disease
Decreased blood levels of a protein called Klotho increases the risk of heart disease in mice with chronic kidney disease, researchers report. If confirmed in humans, increasing Klotho levels may help protect the hearts of patients with chronic kidney disease. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - December 5, 2014 Category: Science Source Type: news

Identifying the cellular origin of fibrosis
(Brigham and Women's Hospital) Researchers from Brigham and Women's Hospital have identified what they believe to be the cells responsible for fibrosis, the buildup of scar tissue. Fibrotic diseases, such as chronic kidney disease and failure, lung disease, heart failure and cirrhosis of the liver, are estimated to be responsible for up to 45 percent of deaths in the developed world. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 2, 2014 Category: Global & Universal Source Type: news

New therapeutic strategy for chronic kidney disease
Chronic kidney disease (CKD) affects at least one in four Americans who are older than 60 and can significantly shorten lifespan. Yet the few available drugs for CKD can only modestly delay the disease’s progress towards kidney failure. Now, a team has found an aspect of CKD’s development that points to a promising new therapeutic strategy. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - December 1, 2014 Category: Science Source Type: news

Incidence of Fracture in Chronic Kidney DiseaseIncidence of Fracture in Chronic Kidney Disease
How common are falls and fractures in adults with chronic kidney disease, and how does this risk help clinicians with patient management and decision making? Kidney International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 28, 2014 Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news

NICE sets out standards for treating patients with renal failure
A new quality standard that sets out how best to care for adults who need treatment for chronic kidney disease has been published by the National Institute for Health and Care Excellence. (Source: Nursing Times Breaking News)
Source: Nursing Times Breaking News - November 28, 2014 Category: Nursing Source Type: news

Encouraging Results For Two New Drugs That Fight A Common And Dangerous Side Effect
Two new agents under development may help curb and prevent elevated potassium levels, the common and serious side effect of drugs that inhibit the renin-angiotensin-aldosterone system (RAAS). These drugs, which include the popular ACE inhibitors and ARBs, are the cornerstones of the treatment of chronic kidney disease and heart failure. Current treatments for high potassium levels, also called hyperkalemia, are often poorly tolerated and ineffective, meaning that a substantial number of seriously ill patients with heart failure and chronic kidney disease can't receive the full benefits of the RAAS drugs. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - November 21, 2014 Category: Pharmaceuticals Authors: Larry Husten Source Type: news

CKD: Exercise May Improve Pain, Physical Function CKD: Exercise May Improve Pain, Physical Function
Patients with chronic kidney disease improved on fitness tests and quality-of-life measures after completing a 12-week exercise program. Medscape Medical News (Source: Medscape Nephrology Headlines)
Source: Medscape Nephrology Headlines - November 21, 2014 Category: Urology & Nephrology Tags: Nephrology News Source Type: news

Investigational drug reduces high potassium levels in chronic kidney disease patients
(University of Maryland Medical Center) Research published today found that the investigational drug patiromer decreased high potassium levels and maintained normal potassium levels in patients with chronic kidney disease. The results of a multicenter trial appear in the New England Journal of Medicine. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 21, 2014 Category: Global & Universal Source Type: news

Biomarker could provide early warning of kidney disease in cats
A new biomarker called 'SDMA' has been developed that can provide earlier identification of chronic kidney disease in cats, which is one of the leading causes of their death. When a test is commercialized, it could help pet owners add months or years to the life of their cat. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 20, 2014 Category: Science Source Type: news

Biomarker could provide early warning of kidney disease in cats
(Oregon State University) Researchers have developed a new biomarker called 'SDMA' that can provide earlier identification of chronic kidney disease in cats, which is one of the leading causes of their death. When a test is commercialized, it could help pet owners add months or years to the life of their cat. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - November 20, 2014 Category: Global & Universal Source Type: news

Bleeding Risk Highest in Kidney Disease When Warfarin StartsBleeding Risk Highest in Kidney Disease When Warfarin Starts
Patients with chronic kidney disease experience the greatest risk for major bleeding in the first 30 days after starting warfarin. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 19, 2014 Category: Consumer Health News Tags: Nephrology News Source Type: news

Air Pollution May Be Linked to Higher Rates of Kidney Disease
Study found other risk factors, including age and diabetes, don't fully explain variations in rates Source: HealthDay Related MedlinePlus Pages: Air Pollution, Chronic Kidney Disease (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - November 15, 2014 Category: Consumer Health News Source Type: news

Chronic kidney disease: Exercise provides clear benefits
Simple exercises can help improve the health of patients with kidney disease, experts say. Heart disease is the leading cause of death in patients with chronic kidney disease (CKD). Because exercise capacity is significantly reduced in CKD patients, experts examined the effect of 12 months of exercise training on kidney function and measures of heart disease risk in patients with progressive CKD stages 3-4. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 15, 2014 Category: Science Source Type: news

Keryx announces results from ferric citrate phase 3 long-term safety extension study
(Edelman Public Relations) Keryx Biopharmaceuticals, Inc. today announced results from a 48-week Open Label Extension (OLE) safety study in which Ferric Citrate demonstrated long-term safety and efficacy in dialysis-dependent chronic kidney disease patients with elevated serum phosphorus levels, or hyperphosphatemia. The OLE findings were presented as a late-breaking poster (Abstract #SA-PO1102) at the 2014 American Society of Nephrology's Kidney Week meeting in Philadelphia, Pa. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 15, 2014 Category: Global & Universal Source Type: news

Sleep apnea may contribute to kidney disease progression
This study shows that a high-risk score for obstructive sleep apnea is common in non-dialysis chronic kidney disease (CKD) patients with diabetic nephropathy and is associated with more rapid loss of renal function," the investigators concluded. "This simple approach identifies patients at higher risk of CKD progression." (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 14, 2014 Category: Science Source Type: news

Nearly all patients with chronic kidney disease should take statins, guidelines indicate
A comparison of two different cholesterol management guidelines indicates that the vast majority of patients with chronic kidney disease are recommended to receive statins. 50% of people with chronic kidney disease who are recommended to receive statins are not taking them, the study shows. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 14, 2014 Category: Science Source Type: news

Most Patients with Chronic Kidney Disease Eligible for Statin Therapy (FREE)
By Kelly Young Edited by André Sofair, MD, MPH, and William E. Chavey, MD, MS The Kidney Disease Improving Global Outcomes Lipid Work Group recommends statins for all CKD patients aged 50 and older, but only half of patients … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - November 14, 2014 Category: Primary Care Source Type: news

Sickle Cell 'Trait' Linked to Chronic Kidney Disease - 11/13/14
Sickle cell trait (SCT), an inherited condition marked by having a single copy of the sickle cell gene but not the two copies needed to cause sickle cell disease (SCD), may raise the risk of chronic kidney disease, according to results of a large study led by researchers from Johns Hopkins, the University of North Carolina at Chapel Hill, the University of Mississippi Medical Center, the Fred Hutchinson Cancer Research Center and the University of Washington School of Public Health. (Source: Johns Hopkins Medicine News)
Source: Johns Hopkins Medicine News - November 13, 2014 Category: Research Source Type: news

Sertraline Treatment No Benefit for Depressive Symptoms in CKD
No improvement for patients with MDD and chronic kidney disease without dialysis dependence (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - November 11, 2014 Category: Psychiatry Tags: Family Medicine, Internal Medicine, Nephrology, Pharmacy, Psychiatry, Journal, Source Type: news

Cognition Deficits Seen in Children With Chronic Kidney Disease
Children with less severe CKD and kidney transplant had higher full - scale IQ than those on dialysis (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - November 11, 2014 Category: Psychiatry Tags: Nephrology, Neurology, Pediatrics, Psychiatry, Journal, Source Type: news

Complete Inhibition of the Renin-angiotensin-aldosterone SystemComplete Inhibition of the Renin-angiotensin-aldosterone System
Are there adverse events associated with renin-angiotensin-aldosterone system blockade in combination with monotherapy in individuals with chronic kidney disease? Current Opinion in Nephrology and Hypertension (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 10, 2014 Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news

FDA Panel Votes to Recommend New Iron Replacement TreatmentFDA Panel Votes to Recommend New Iron Replacement Treatment
An FDA advisory panel has voted to recommend approval of a new treatment that replaces iron lost during hemodialysis in patients with chronic kidney disease. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 7, 2014 Category: Consumer Health News Tags: Nephrology News Source Type: news

Mediterranean diet may help protect kidney health
Every one-point increase in a Mediterranean diet score was associated with a 17% decreased likelihood of developing chronic kidney disease, a study concludes. Dietary patterns that closely resembled the Mediterranean diet were linked with a 50% reduced risk of developing chronic kidney disease and a 42% reduced risk of experiencing rapid kidney function decline, the researchers add. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - October 31, 2014 Category: Science Source Type: news

Akebia’s Phase IIb AKB-6548 anaemia trial meets primary endpoint
US-based biopharmaceutical firm Akebia Therapeutics has reported positive top-line results from its Phase IIb placebo-controlled trial of its once-daily, oral therapy, AKB-6548, in non-dialysis patients with anaemia related to chronic kidney disease … (Source: Drug Development Technology)
Source: Drug Development Technology - October 28, 2014 Category: Pharmaceuticals Source Type: news

CKD: Exercise Beneficial in Chronic Kidney DiseaseCKD: Exercise Beneficial in Chronic Kidney Disease
Patients who exercised had lower mortality and better quality of life. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 23, 2014 Category: Consumer Health News Tags: Nephrology News Source Type: news

Chronic Kidney Disease and ICD Related ComplicationsChronic Kidney Disease and ICD Related Complications
Find out more about the association between kidney function and the occurrence of ICD related complications. Journal of Cardiovascular Electrophysiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 14, 2014 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

Diabetic Retinopathy a Prognostic Factor for CKD ProgressionDiabetic Retinopathy a Prognostic Factor for CKD Progression
This study examines the role of diabetic retinopathy as a potential prognostic factor for the progression of chronic kidney disease. Eye (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 9, 2014 Category: Consumer Health News Tags: Ophthalmology Journal Article Source Type: news

Insulin Resistance in Chronic Kidney DiseaseInsulin Resistance in Chronic Kidney Disease
How should clinicians go about measuring insulin resistance in patients with chronic kidney disease, and how will it better help them to both evaluate and treat the disease? Kidney International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 29, 2014 Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news

Akebia starts dosing in Phase II trial of AKB-6548 in anaemia patients
US-based biopharmaceutical firm Akebia Therapeutics has dosed the first patient in its Phase II clinical trial of AKB-6548 in patients with anaemia related to chronic kidney disease (CKD) undergoing dialysis. (Source: Drug Development Technology)
Source: Drug Development Technology - September 28, 2014 Category: Pharmaceuticals Source Type: news

Kidney Disease in the Obese PatientKidney Disease in the Obese Patient
Obese patients have a strong risk for chronic kidney disease. Learn the epidemiology, presentation, and proposed mechanisms for CKD in the obese patient in this review. Southern Medical Journal (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 23, 2014 Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news

Burnt sugarcane harvesting is associated with acute renal dysfunction - Paula Santos U, Zanetta DM, Terra-Filho M, Burdmann EA.
Sugarcane harvesting has been associated with an epidemic of chronic kidney disease in Central America mainly affecting previously healthy young workers. Repeated episodes of acute kidney dysfunction are hypothesized to be one of the possible mechanisms fo... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - September 20, 2014 Category: Global & Universal Tags: Occupational Issues Source Type: news

Study: CardioMEMs implanted heart monitor safe for renal failure patients
New data from CardioMEMs CHAMPION clinical trial shows that the company's implanted pulmonary artery pressure monitor helps reduce heart failure hospitalizations without compromising kidney function in patients with renal failure. St. Jude Medical (NYSE:STJ) subsidiary CardioMEMs touted new study results this week showing that its implanted heart monitor is safe and effective in patients with chronic kidney disease. CardioMEMS Inc., St. Jude MedicalNews Well, Clinical Trials, Cardiovascular, Implants, Renalread more (Source: Mass Device)
Source: Mass Device - September 16, 2014 Category: Medical Equipment Authors: Arezu Sarvestani Source Type: news