Oral Health in Patients With Chronic Kidney DiseaseOral Health in Patients With Chronic Kidney Disease
An increase in chronic kidney disease is bringing more such patients to the dentist's chair. Medscape Dental & Oral Health (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 4, 2014 Category: Consumer Health News Tags: Dental & Oral Health Viewpoint Source Type: news

Director's Comments: Chronic Kidney Disease Mystery in Central America
Listen to the NLM Director's Comments on "Chronic Kidney Disease Mystery in Central America". The transcript is also available. As the number of Central American young adults with chronic kidney disease increase, a medical mystery percolates about the disease’s underlying causes, finds an article recently published in Science... (Source: What's New on MedlinePlus)
Source: What's New on MedlinePlus - June 2, 2014 Category: Consumer Health News Source Type: news

New Oral Compound Redresses Metabolic Abnormalities in CKDNew Oral Compound Redresses Metabolic Abnormalities in CKD
A new oral iron compound significantly reduces serum phosphate and increases low iron stores in patients with chronic kidney disease (CKD) and anemia, early trial results show. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 2, 2014 Category: Consumer Health News Tags: Nephrology News Source Type: news

Researchers discover hormone that controls supply of iron in red blood cell production
A UCLA research team has discovered a new hormone called erythroferrone, which regulates the iron supply needed for red blood-cell production. Iron is an essential functional component of hemoglobin, the molecule that transports oxygen throughout the body. Using a mouse model, researchers found that erythroferrone is made by red blood-cell progenitors in the bone marrow in order to match iron supply with the demands of red blood-cell production. Erythroferrone is greatly increased when red blood-cell production is stimulated, such as after bleeding or in response to anemia. The erythroferrone hormone acts by regulating the...
Source: UCLA Newsroom: Health Sciences - June 1, 2014 Category: Universities & Medical Training Source Type: news

Reduced kidney function associated with higher risk of renal and urothelial cancer
(University of Utah Health Sciences) Researchers who investigated the level of kidney function and subsequent cancer risk in more than one million adults have found that reduced glomerular filtration rate -- a key measure of reduced kidney function and chronic kidney disease -- is an independent risk factor for renal and urothelial cancer but not other cancer types. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 29, 2014 Category: Cancer & Oncology Source Type: news

Reduced kidney function associated with higher risk of renal and urothelial cancer
(Kaiser Permanente) A key measure of reduced kidney function and chronic kidney disease -- reduced glomerular filtration rate -- is an independent risk factor for renal and urothelial cancer, according to a study published online today in the Journal of the American Society of Nephrology. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 29, 2014 Category: Cancer & Oncology Source Type: news

In Advanced CKD, Thiazide May Help Control BPIn Advanced CKD, Thiazide May Help Control BP
Dr. George Bakris interviews Dr. Rajiv Agarwal about a small study that could redeem chlorthalidone's role in controlling blood pressure in patients with moderate to advanced chronic kidney disease. Medscape Nephrology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 20, 2014 Category: Consumer Health News Tags: Nephrology Commentary Source Type: news

Walking may have profound benefits for patients with kidney disease
Among patients with chronic kidney disease who were followed for an average of 1.3 years, those who walked for exercise were 33% less likely to die and 21% less likely to need dialysis or a kidney transplant. Physical inactivity is common among patients with chronic kidney disease (CKD). The researchers found that the presence of other, or comorbid, conditions such as cardiovascular disease and diabetes was similar between walking and non-walking patients. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 15, 2014 Category: Science Source Type: news

Walking Could Be Key Step Against Kidney Disease
The more patients walked, the less their odds for early death or need for dialysis, study found Source: HealthDay Related MedlinePlus Pages: Chronic Kidney Disease, Exercise and Physical Fitness (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - May 15, 2014 Category: Consumer Health News Source Type: news

Deadly Illness in Nicaragua Baffles Experts
Across Central America, a kidney disease has killed at least 20,000 people over a decade and is so poorly understood that it does not have a universally agreed upon name. (Source: NYT Health)
Source: NYT Health - May 9, 2014 Category: Consumer Health News Authors: By HEATHER MURPHY Tags: Nicaragua Centers for Disease Control and Prevention World Bank Coca-Cola Company KO NYSE Chronic Kidney Disease of unknown causes Sugar Kidneys Labor and Jobs Source Type: news

Lowering LDL Doesn't Slow Progression to ESRD (CME/CE)
(MedPage Today) -- Lowering LDL cholesterol in patients with chronic kidney disease does not appear to slow progression to end-stage renal disease (ESRD), a study reports. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - May 2, 2014 Category: Cardiology Source Type: news

Statins for kidney disease patients: Protection for heart but no effects on kidneys
For patients with chronic kidney disease, statin treatment appears to lower LDL cholesterol, decrease the risk of heart disease and stroke, and has no impact on the development of kidney failure, research concluded. Investigators have said that statin treatment is safe and well tolerated for those with chronic kidney disease. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 1, 2014 Category: Science Source Type: news

LDL-Lowering Does Not Halt Progression of CKD: SHARPLDL-Lowering Does Not Halt Progression of CKD: SHARP
Lowering LDL cholesterol by 37.1 mg/dL with a combination of simvastatin and ezetimibe failed to halt the progression of kidney disease to end-stage renal disease in patients with chronic kidney disease. Heartwire (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - May 1, 2014 Category: Cardiology Tags: Cardiology News Source Type: news

Statins Don't Prevent Kidney Disease Progression, Study Finds
But the drugs do help lower cholesterol in these patients, researchers say Source: HealthDay Related MedlinePlus Pages: Cholesterol, Chronic Kidney Disease, Statins (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - May 1, 2014 Category: Consumer Health News Source Type: news

Experimental drug prolongs life span in mice
Scientists newly identified a protein's key role in cell and physiological aging and have developed an experimental drug that inhibits the protein's effect and quadrupled the lifespan in a mouse model of accelerated aging. Their lungs and vascular system were protected from rapid aging. The experimental drug could potentially be used to treat human diseases that cause accelerated aging such as chronic kidney disease, diabetes and HIV infection and even extend someone's healthy life. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 1, 2014 Category: Science Source Type: news

Failing Kidneys and Cancer: Is There a Link?
LAS VEGAS (MedPage Today) -- Patients with chronic kidney disease (CKD) stage III or higher may be at greater risk for cancer, researchers reported here. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - April 24, 2014 Category: Cardiology Source Type: news

Kidney injuries 'killing thousands,' study claims
ConclusionThis valuable study provides an estimate of the likely prevalence of AKI among inpatients in NHS hospitals. Comparison of HES data with laboratory data obtained from the three EKHUFT hospitals (where the AKIN classification system was used to define AKI cases), suggests that prevalence could be much higher than thought, and that there could be considerable under-recording of cases in the NHS. The study also highlights the high mortality associated with AKI – accounting for an estimated 40,000 excess inpatient deaths. AKI was also associated with considerable loss to quality of life. Looking at the financial...
Source: NHS News Feed - April 23, 2014 Category: Consumer Health News Tags: Medical practice Source Type: news

Kidney damage 'killing thousands,' study claims
Conclusion This valuable study provides an estimate of the likely prevalence of AKI among inpatients in NHS hospitals. Comparison of HES data with laboratory data obtained from the three EKHUFT hospitals (where the AKIN classification system was used to define AKI cases), suggests that prevalence could be much higher than thought, and that there could be considerable under-recording of cases in the NHS. The study also highlights the high mortality associated with AKI – accounting for an estimated 40,000 excess inpatient deaths. AKI was also associated with considerable loss to quality of life. Looking at the financi...
Source: NHS News Feed - April 23, 2014 Category: Consumer Health News Tags: Medical practice Source Type: news

CKD: Is Birth Weight a Risk Factor? (CME/CE)
(MedPage Today) -- Prenatal programming is suspected of playing a role in certain renal diseases in adults, and there is now evidence that it may also put children at risk for chronic kidney disease (CKD). (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - April 18, 2014 Category: Endocrinology Source Type: news

Prenatal risk factors may put children at risk of developing kidney disease
Certain prenatal risk factors are associated with the development of chronic kidney disease in children, according to a study. Future studies should investigate whether modifying these factors could help protect children’s kidney health. Risks for certain types of kidney disease may arise before birth, and researchers suspect that the development of chronic kidney disease (CKD) may be programmed prenatally. These may include birth weight, maternal diabetes, and maternal overweight/obesity. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 17, 2014 Category: Science Source Type: news

Maternal Diabetes Linked to Childhood Kidney Disease Maternal Diabetes Linked to Childhood Kidney Disease
Low birth weight, as well as maternal obesity, has been linked to the development of chronic kidney disease in children. Medscape Medical News (Source: Medscape Nephrology Headlines)
Source: Medscape Nephrology Headlines - April 17, 2014 Category: Urology & Nephrology Tags: Nephrology News Source Type: news

Common virus may cause anemia in patients with kidney disease
Kidneys from most patients with chronic kidney disease in a new study were positive for active cytomegalovirus infection. Patients with higher levels of anti-cytomegalovirus antibodies in their blood had lower number of red blood cells. Cytomegalovirus blocks a protein needed to make a hormone that in turn stimulates red blood cell production. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 10, 2014 Category: Science Source Type: news

DNA Vaccination as a Treatment for Chronic Kidney Disease
Chronic kidney disease is one of the major health problems worldwide. DNA vaccination delivers plasmid DNA encoding the target gene to induce both humoral and cellular immune responses. Here, we describe the methods of CD40 DNA vaccines enhanced by dendritic cell (DC) targeting on the development of Heymann nephritis (HN), a rat model of human membranous nephropathy. (Source: Springer protocols feed by Immunology)
Source: Springer protocols feed by Immunology - April 10, 2014 Category: Allergy & Immunology Source Type: news

Vigilance for Kidney Problems Key for Rheumatoid Arthritis Patients
MULTIMEDIA ALERT: Mayo Clinic study finds rheumatoid arthritis patients at higher risk of kidney disease ROCHESTER, Minn. — Rheumatoid arthritis patients are likelier than the average person to develop chronic kidney disease, and more severe inflammation in the first year of rheumatoid arthritis, corticosteroid use, high blood pressure and obesity are among the risk factors, new [...] (Source: Mayo Clinic Rochester News)
Source: Mayo Clinic Rochester News - April 9, 2014 Category: Hospital Management Source Type: news

Managing chronic kidney disease in primary care: a practice guide for practice nurses
This article explores who is at risk of developing CKD, how it is detected, long-term monitoring and when to refer for specialist assessment. What is CKD? Hide related content:  Show related content Featured In Issue:  Nursing in Practice March/April 2014, Number 77 read more (Source: Nursing in Practice)
Source: Nursing in Practice - April 8, 2014 Category: Nursing Authors: Lalah-Simone Springer Tags: Men ' s health Women Source Type: news

Poor quality of life may contribute to kidney disease patients' health problems
In African American patients with chronic kidney disease, poor quality of life was linked with increased risks of disease progression and heart problems. Approximately 60 million people globally have chronic kidney disease (CKD). Quality of life has been well-studied in patients with end-stage kidney disease, but not in patients with CKD who do not yet require dialysis. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 4, 2014 Category: Science Source Type: news

Doctors launch new tool to measure your 'heart age'
“People are being urged to find out their "true" heart age in order to cut the risk of heart attacks and strokes,” BBC News reports. Doctors have put together a new risk calculator called JBS3 that can tell you the real “age” of your heart. Risk calculators for cardiovascular diseases or CVDs (conditions that affect the heart and blood vessels) are nothing new. The “granddaddy” of risk calculators – the Framingham risk calculator – has been available for years. But this new JBS3 calculator has the benefits of: being easily accessible online providing what is t...
Source: NHS News Feed - March 27, 2014 Category: Consumer Health News Tags: Heart/lungs QA articles Source Type: news

Stem cells from the body's fatty folds may preserve and improve kidney function
A fatty fold of tissue within the abdomen that is a rich source of stem cells can help heal diseased kidneys when fused to the organs, according to a study conducted in rats. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology (JASN) suggest that stem cells from within a chronic kidney disease patient's own abdomen could be used to preserve and possibly improve kidney function.Although adult stem cells have shown promise in treating experimental acute kidney diseases, it's unknown whether they might also alleviate chronic kidney diseases. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 25, 2014 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news

Body's fatty folds may help fight kidney failure
(American Society of Nephrology) In rats with kidney disease, functioning of the kidney improved when the organ was fused with the omentum, a fatty fold of tissue that lies close to the kidney and is a rich source of stem cells. Stem cells from a chronic kidney disease patient's own omentum may help heal diseased kidneys without the need for an outside source of cells. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 21, 2014 Category: Global & Universal Source Type: news

Intraocular Pressure and HemodialysisIntraocular Pressure and Hemodialysis
The convergence of glaucoma and chronic kidney disease in the same population means that hemodialysis could be an important factor in control of intraocular pressure. Medscape Ophthalmology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 17, 2014 Category: Consumer Health News Tags: Ophthalmology Viewpoint Source Type: news

Kidney failure of unknown cause baffles Sri Lankan doctors
SRI JAYAWARDENEPURA KOTTE, Sri Lanka, March 15 (UPI) -- Doctors in Sri Lanka say an "unknown plague" involving chronic kidney disease of unknown cause is putting families at risk and young people are migrating. (Source: Health News - UPI.com)
Source: Health News - UPI.com - March 15, 2014 Category: Consumer Health News Source Type: news

Chronic Kidney Disease and the Aging PopulationChronic Kidney Disease and the Aging Population
As the general population ages, more people will develop and be at risk for chronic kidney disease. How can clinicians educate the public about the dangers of the disease? Nephrology Dialysis Transplantation (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 14, 2014 Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news

Body's fatty folds may help fight kidney failure
In a new study, it was observed that in rats with kidney disease, functioning of the kidney improved when the organ was fused with the omentum, a fatty fold of tissue that lies close to the kidney and is a rich source of stem cells. The findings suggest that stem cells from a chronic kidney disease patient’s own omentum may help heal diseased kidneys without the need for an outside source of cells. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 13, 2014 Category: Science Source Type: news

La Jolla's GCS-100 Improves Kidney Function In Study
La Jolla Pharmaceutical Co announced positive top-line results from its Phase II trial evaluating GCS-100 for treatment in chronic kidney disease (CKD). The company’s shares rose about 40 percent in extended trading following the news. (Source: Pharmaceutical Online News)
Source: Pharmaceutical Online News - March 13, 2014 Category: Pharmaceuticals Source Type: news

La Jolla Pharma's Drug Improves Kidney Function in TrialLa Jolla Pharma's Drug Improves Kidney Function in Trial
La Jolla Pharmaceutical Co said its lead experimental drug to treat chronic kidney disease met the main goal of improving kidney function in a mid-stage study. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 12, 2014 Category: Consumer Health News Tags: Nephrology News Source Type: news

La Jolla Pharma's drug improves kidney function in trial, shares soar
(Reuters) - La Jolla Pharmaceutical Co said its lead experimental drug to treat chronic kidney disease met the main goal of improving kidney function in a mid-stage study, sending the company's shares up about 40 percent in extended trading. (Source: Reuters: Health)
Source: Reuters: Health - March 10, 2014 Category: Consumer Health News Tags: healthNews Source Type: news

La Jolla Pharma's drug improves kidney function in trial
(Reuters) - La Jolla Pharmaceutical Co said its experimental drug to treat chronic kidney disease met the main goal of improving kidney function in a mid-stage study, sending the company's shares up 28 percent in extended trading. (Source: Reuters: Health)
Source: Reuters: Health - March 10, 2014 Category: Consumer Health News Tags: healthNews Source Type: news

Blood Pressure in CKD: 'The Lower the Better' Still ValidBlood Pressure in CKD: 'The Lower the Better' Still Valid
Despite a recent study to the contrary, Dr. Henry Black doesn't think we should aim for stage 1 hypertension in patients with chronic kidney disease. Medscape Cardiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 6, 2014 Category: Consumer Health News Tags: Cardiology Commentary Source Type: news

Active vitamin D helps remove toxic aluminum in chronic kidney disease patients
(Source: NaturalNews.com)
Source: NaturalNews.com - March 6, 2014 Category: Consumer Health News Source Type: news

Study points to new biological mechanisms, treatment paradigm for kidney disease
Prevention and reversal of chronic kidney disease is an urgent public health need. The disease affects 1 in 10 Americans, is debilitating and deadly, and existing drugs, at best, offer only mild delay in progression to end-stage kidney failure. New research led by Icahn School of Medicine at Mount Sinai investigators has uncovered abnormal molecular signaling pathways from disease initiation to irreversible kidney damage, kidney failure, and death. Results from their preclinical and human research are published online in the Journal of Clinical Investigation. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 5, 2014 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news

AFib Patients with Chronic Kidney Disease Also Benefit from Warfarin (FREE)
By Larry Husten A large observational study, published in JAMA, offers some reassurance that anticoagulation in atrial fibrillation patients who also have chronic kidney disease may be beneficial.Researchers in Sweden analyzed data from … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 5, 2014 Category: Primary Care Source Type: news

Warfarin Benefits Extended To Patients with Chronic Kidney Disease
Anticoagulation is a cornerstone of therapy for atrial fibrillation because it lowers the heightened risk for stroke in this population. People with chronic kidney disease are also at increased risk for stroke, but the benefits of anticoagulation are less clear in this group, and anticoagulation is used less often in AF patients who have CKD. Now, a large observational study offers some reassurance that anticoagulation in AF patients with CKD may be beneficial. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - March 4, 2014 Category: Pharmaceuticals Authors: Larry Husten Source Type: news

Anti-coagulant treatment for atrial fibrillation does not worsen outcomes for patients with kidney disease
Although some research has suggested that the use of the anticoagulant warfarin for atrial fibrillation among patients with chronic kidney disease would increase the risk of death or stroke, a study that included more than 24,000 patients found a lower l-year risk of the combined outcomes of death, heart attack or stroke without a higher risk of bleeding, according to a study in JAMA. Juan Jesus Carrero, Ph.D. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 4, 2014 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news

Warfarin Safe for Kidney Patients with Irregular Heartbeat
Use of the blood thinner may safely ease stroke risk linked to atrial fibrillation, Swedish research finds Source: HealthDay Related MedlinePlus Pages: Blood Thinners, Chronic Kidney Disease (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - March 4, 2014 Category: Consumer Health News Source Type: news

New biological mechanisms, treatment paradigm for kidney disease
Prevention and reversal of chronic kidney disease is an urgent public health need. The disease affects 1 in 10 Americans, is debilitating and deadly, and existing drugs, at best, offer only mild delay in progression to end-stage kidney failure. New research has uncovered abnormal molecular signaling pathways from disease initiation to irreversible kidney damage, kidney failure, and death. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 3, 2014 Category: Science Source Type: news

Mount Sinai study points to new biological mechanisms, treatment paradigm for kidney disease
(The Mount Sinai Hospital / Mount Sinai School of Medicine) Researchers have identified new molecular signaling pathways in chronic kidney disease, pointing to a paradigm shift in treating the disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 3, 2014 Category: Global & Universal Source Type: news

Hemostasis in Chronic Kidney DiseaseHemostasis in Chronic Kidney Disease
How common are bleeding events in patients with impaired renal function receiving anticoagulant treatment, and how important is it for clinicians to carefully prescribe medications in patients with renal impairment? Nephrology Dialysis Transplantation (Source: Medscape Nephrology Headlines)
Source: Medscape Nephrology Headlines - February 28, 2014 Category: Urology & Nephrology Tags: Nephrology Journal Article Source Type: news

Summary of KDIGO 2012 CKD GuidelineSummary of KDIGO 2012 CKD Guideline
What do the latest clinical guidelines say about the pathophysiology of chronic kidney disease, and the best ways to manage and treat it? Kidney International (Source: Medscape Nephrology Headlines)
Source: Medscape Nephrology Headlines - February 27, 2014 Category: Urology & Nephrology Tags: Nephrology Journal Article Source Type: news

March Partner Spotlight
The National Kidney Disease Education Program Showcases NDEP Materials in its Annual Kidney Sundays Event Background The National Kidney Disease Education Program (NKDEP) is a federally sponsored program that works to reduce the burden of chronic kidney disease (CKD) among communities most impacted by the disease. Established in 2000 by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NKDEP aims to raise awareness among people at risk for CKD about the need for testing and educate people with CKD about how to manage their disease...
Source: National Diabetes Education Program - February 27, 2014 Category: Endocrinology Source Type: news

La Jolla completes dosing patients in Phase II study of chronic kidney disease
US-based La Jolla Pharmaceutical has completed dosing in its Phase II clinical study of GCS-100 for the treatment of chronic kidney disease (CKD) and has also collected the final data for assessment of the primary endpoint. (Source: Drug Development Technology)
Source: Drug Development Technology - February 24, 2014 Category: Pharmaceuticals Source Type: news