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Donor dilemma
When her daughter, Thalya, was diagnosed with chronic kidney disease, Chantal Onelien's initial reaction was shock. But, as Adam Harris reports, it was only the beginning of a long and difficult fight. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - February 6, 2017 Category: Consumer Health News Source Type: news

Skin sodium content linked to heart problems in patients with kidney disease
Elevated sodium content in the skin correlates closely with left ventricular hypertrophy in patients with chronic kidney disease, report researchers. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 3, 2017 Category: Science Source Type: news

IV contrast for CT is not associated with increased risk of acute kidney injury
Intravenous contrast media (typically iohexol or iodixanol) used in computed tomography (CT) does not appear to be associated with chronic kidney disease, dialysis, kidney transplant or acute kidney injury, despite long-held fears to the contrary. The results of the largest controlled study of acute kidney injury following contrast media administration in the emergency department were just published. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 26, 2017 Category: Science Source Type: news

IV contrast for CT is not associated with increased risk of acute kidney injury
(American College of Emergency Physicians) Intravenous contrast media (typically iohexol or iodixanol) used in computed tomography (CT) does not appear to be associated with chronic kidney disease, dialysis, kidney transplant or acute kidney injury, despite long-held fears to the contrary. The results of the largest controlled study of acute kidney injury following contrast media administration in the emergency department were published online yesterday in Annals of Emergency Medicine ('Risk of Acute Kidney Injury Following Intravenous Contrast Media Administration'). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 26, 2017 Category: Global & Universal Source Type: news

Ferric Citrate Improves Iron-Deficiency Anemia in Chronic Kidney Disease Ferric Citrate Improves Iron-Deficiency Anemia in Chronic Kidney Disease
Oral treatment with ferric citrate improves iron-deficiency anemia in patients with non-dialysis-dependent chronic kidney disease (NDD-CKD), according to a randomized controlled trial.Reuters Health Information (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - January 20, 2017 Category: Intensive Care Tags: Family Medicine/Primary Care News Source Type: news

Statin Use Associated With Benefits in Early-Stage Kidney Disease Statin Use Associated With Benefits in Early-Stage Kidney Disease
Patients with early-stage chronic kidney disease (CKD) who take statins have reduced mortality and a slower decline in kidney function, though this is not true for patients with more advanced disease, new findings show.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 20, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

CKD care has improved but GPs should conduct more urine tests, report says
GPs have helped cut the need for dialysis among patients with chronic kidney disease (CKD) through earlier diagnosis over the last decade, but greater use of annual urine testing and accurate read coding could boost progress further, according to a clinical audit. (Source: GP Online News)
Source: GP Online News - January 18, 2017 Category: Primary Care Tags: Renal disorders Source Type: news

PAs are Altering the Course of Chronic Kidney Disease
Certified PAs and other healthcare providers can follow this simple assessment protocol to help with early detection of chronic kidney disease. (Source: Physicians Practice)
Source: Physicians Practice - January 17, 2017 Category: Practice Management Authors: Kendra Thomsen, PA-C Tags: Blog CME Staff Tools Source Type: news

Kidney disease patients have higher out-of-pocket costs than stroke and cancer patients
(Loyola University Health System) Patients who have chronic kidney disease but are not on dialysis have higher out-of-pocket healthcare expenses than even stroke and cancer patients, according to a Loyola University Chicago study published in BMC Nephrology. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 17, 2017 Category: Cancer & Oncology Source Type: news

The Challenges of Treating Cancer Patients on Hemodialysis, or With Chronic Kidney Disease
It is challenging to diagnose, manage, and treat patients who have kidney disease in addition to cancer. Second to cardiovascular disease, cancer represents a major cause of mortality and morbidity in the kidney disease population. (Source: CancerNetwork)
Source: CancerNetwork - January 15, 2017 Category: Cancer & Oncology Authors: Charbel C. Khoury, MD David J. R. Steele, MD Tags: Oncology Journal Source Type: news

Trial finds oral iron drug safe, effective for treating anemia in kidney disease patients
In a phase 3 trial of patients with chronic kidney disease, 52.1% of patients receiving oral ferric citrate experienced a significant boost in hemoglobin levels (a reflection of red blood cell counts) compared with 19.1% of patients receiving placebo. A treatment effect was seen as early as 1-2 weeks after the start of treatment, and the response was durable. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 12, 2017 Category: Science Source Type: news

Having a health check could save your life
Regular health checks – which are commissioned by councils as part of their public health duties - are saving lives across the country by identifying early signs of potentially life-threatening conditions. More new cases of diabetes, hypertension, and chronic kidney disease were identified among attendees than a matche d group of non-attendees. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 11, 2017 Category: Consumer Health News Source Type: news

Study Results Published in the Journal of the American Medical Association Show Amgen's Parsabiv ™ (Etelcalcetide) Significantly Reduced Serum Parathyroid Hormone in Adults With Secondary Hyperparathyroidism on Hemodialysis
THOUSAND OAKS, Calif., Jan. 10, 2017 /PRNewswire/ -- Amgen (NASDAQ:AMGN) today announced the Journal of the American Medical Association (JAMA) publication of findings from three Phase 3 studies of Parsabiv™ (etelcalcetide), an investigational intravenous calcimimetic agent in the U.S. The studies evaluated Parsabiv in more than 1,700 adults with secondary hyperparathyroidism (sHPT) on hemodialysis and showed that the drug produced statistically significant and clinically meaningful reductions in serum parathyroid hormone (PTH) levels, a key marker of sHPT. sHPT is a chronic and serious condition that is often p...
Source: Amgen News Release - January 10, 2017 Category: Pharmaceuticals Tags: Uncategorized Source Type: news

' Goldilocks' drug prevents chronic kidney disease in primates
A research team has developed a way to avoid ischemia/reperfusion injury of the kidney with a new monoclonal antibody that binds its target receptor in a way that is'just right.'(Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 10, 2017 Category: Science Source Type: news

Metformin Associated with Lower Mortality Risk in Heart Failure, Chronic Kidney Disease (FREE)
By Kelly Young Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD Use of metformin is associated with reduced mortality in patients with diabetes plus chronic heart failure (CHF), chronic kidney disease (CKD), or chronic liver disease, according … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - January 2, 2017 Category: Primary Care Source Type: news

Breast and cervical cancer screening rates are low in women with advanced kidney disease
(American Society of Nephrology) In a recent study, most women with advanced chronic kidney disease had not received breast or cervical cancer screening in recent years. Older age, greater comorbidities, and lower income were associated with a lower rate of screening. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 29, 2016 Category: Global & Universal Source Type: news

Keeping the Resolve in Your New Year's Resolutions
Losing weight is a top New Year's resolution for many Americans. Reaching and staying at a healthy weight are resolutions worth keeping--not just throughout the year, but throughout a lifetime. Avoiding overweight and obesity may help reduce the risk of developing a host of health problems, including diabetes, chronic kidney disease, heart disease, and some types of cancer. With more than 2 in 3 American adults considered overweight or obese, maintaining a healthy weight is a major public health concern. Setting Goals and Creating an Action Plan If you've resolved to lose weight, you're more likely to keep your resoluti...
Source: Healthy Living - The Huffington Post - December 23, 2016 Category: Consumer Health News Source Type: news

HF Risk Outweighs Stroke in Chronic Kidney Disease
(MedPage Today) -- Observed risk particularly high in African Americans and Hispanics (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - December 21, 2016 Category: Urology & Nephrology Source Type: news

​Cambridge’s Akebia announces deal worth $170M now, maybe over $1B later
Cambridge-based Akebia Therapeutics has announced a collaboration and license agreement in the U.S. for its anemia drug with a Japanese drugmaker under which it will get $160 million in coming months and potentially more than $1 billion in coming years. The agreement between Akebia (Nadsaq: AKBA) and Otsuka Pharmaceutical Co. is related to Akebia’s drug, vadadustat, which is now in development for the treatment of anemia associated with chronic kidney disease. Anemia related to CKD affects an… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - December 20, 2016 Category: Pharmaceuticals Authors: Don Seiffert Source Type: news

PCI Without Contrast in Advanced Renal Failure PCI Without Contrast in Advanced Renal Failure
The authors report on a novel strategy for safely performing PCI without the use of contrast in patients with advanced chronic kidney disease.European Heart Journal (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 19, 2016 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

Protein in urine linked to increased risk of memory problems
Chronic kidney disease and dementia share many risk factors, researchers point out Related items fromOnMedica Constipation linked to kidney disease Dementia now leading cause of death in England and Wales Memory clinic referral criteria delay diagnosis 'Watch and wait' might be better in advanced kidney cancer (Source: OnMedica Latest News)
Source: OnMedica Latest News - December 14, 2016 Category: UK Health Source Type: news

Proteon Therapeutics kidney drug fails key study, shares slump
(Reuters) - Proteon Therapeutics Inc said on Tuesday that its experimental chronic kidney disease drug failed to meet the main goal in a late-stage study, sending its shares plunging 70 percent in premarket trading. (Source: Reuters: Health)
Source: Reuters: Health - December 13, 2016 Category: Consumer Health News Tags: healthNews Source Type: news

Cardiovascular complications of renal disease
Aetiology and management of risk factors for cardiovascular disease in patients with chronic kidney disease and the use of beta-blockers, statins, diuretics and anticoagulants in controlling progression of disease. (Source: GP Online Education)
Source: GP Online Education - December 13, 2016 Category: Primary Care Tags: 15.1 Cardiovascular Problems Source Type: news

Bone marrow-derived cells are source of key kidney disease biomarker SuPAR
A protein that is a reliable biomarker for chronic kidney disease originates in the bone marrow, new research suggests. This discovery of where the suPAR protein is an important step towards earlier detection -and possible prevention -- of a disease suffered by one in 10 adults, kills 48,000 people and costs Medicare $49 billion each year (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - December 12, 2016 Category: Science Source Type: news

Major depression and long-term outcomes of acute kidney injury - Balogun RA, Omotoso BA, Xin W, Ma JZ, Scully KW, Arogundade FA, Abdel-Rahman EM.
This study determines the prognostic implication of a diagnosi... (Source: SafetyLit)
Source: SafetyLit - December 10, 2016 Category: Global & Universal Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Healthy Diet May Mean Longer Life for Kidney Patients
Study found eating lots of fruit, vegetables, fish, whole grains was linked to lower rate of early death Source: HealthDay Related MedlinePlus Pages: Chronic Kidney Disease, Nutrition (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - December 9, 2016 Category: Consumer Health News Source Type: news

Healthy Diet May Mean Longer Life for Kidney Patients
THURSDAY, Dec. 8, 2016 -- A healthy diet may help people with kidney disease live longer, researchers report. They analyzed seven studies that included more than 15,000 people with chronic kidney disease, to assess the effects of a diet high in... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - December 8, 2016 Category: Journals (General) Source Type: news

Kidney disease hospitalization and mortality rates continue to decline in the US
(University of Michigan Health System) According to an annual data report from the United States Renal Data System (USRDS), hospitalization and mortality rates for patients with chronic kidney disease continue to decline in the US. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 2, 2016 Category: Global & Universal Source Type: news

Fetal and Neonatal Renal Failure and Renal Transplant
Major advances have been made over the past few decades in caring for neonates with chronic renal disease. Although dialysis registries report infants as a high-risk population for poor outcomes, these children can be effectively maintained on dialysis until they are ready for receiving a transplant. Early identification of the presence of chronic renal disease is helpful in preparing for postnatal complications and to counsel parents on potential outcomes of infants with chronic kidney disease. (Source: NeoReviews recent issues)
Source: NeoReviews recent issues - November 30, 2016 Category: Pediatrics Authors: Wong, C. J. Tags: Pediatric Drug Labeling Update Complex Fetal Care Source Type: news

Assessing Fluid Status and Physical Function in Patients With CKD Assessing Fluid Status and Physical Function in Patients With CKD
Dr Desai discusses new methods of evaluating body composition and physical function in patients with chronic kidney disease who are not on dialysis.Medscape Nephrology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 28, 2016 Category: Consumer Health News Tags: Nephrology Viewpoint Source Type: news

GSK initiates Phase III programme of daprodustat
UK drug manufacturer GlaxoSmithKline (GSK) has initiated its Phase III programme of daprodustat being developed to treat anaemia associated with chronic kidney disease (CKD). (Source: Drug Development Technology)
Source: Drug Development Technology - November 28, 2016 Category: Pharmaceuticals Source Type: news

Baxter touts blood purification efficiency in EBP studies
Baxter (NYSE:BAX) today released data from 2 studies on extracorporeal blood purification studies, touting the blood purification method’s ability to remove harmful molecules linked to inflammation. Extracorporeal blood purification takes place outside the body, with blood passing through a membrane within an extracorporeal circuit to filter harmful molecules and waste products out of the blood, the company said. The clean blood is then returned to the body. The method is commonly used for patients with kidney injuries. Data from the studies was presented at the American Society of Nephrology’s annual Kidn...
Source: Mass Device - November 22, 2016 Category: Medical Equipment Authors: Fink Densford Tags: Blood Management Clinical Trials Baxter Source Type: news

Poor Sleep Linked to Worsening Kidney Disease
SATURDAY, Nov. 19, 2016 -- For people with chronic kidney disease, poor sleep may boost the chances that their illness will worsen, new research suggests. " Short sleep and fragmented sleep are significant yet unappreciated risk factors for chronic... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 19, 2016 Category: Journals (General) Source Type: news

Program Helps With Transition to Renal Replacement Therapy Program Helps With Transition to Renal Replacement Therapy
After completion of a program on the transition from late-stage chronic kidney disease to end-stage renal replacement therapy, patients had a better understanding of their treatment options.Medscape Medical News (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - November 18, 2016 Category: Intensive Care Tags: Nephrology News Source Type: news

Lowering Urate Helps Renal Function
(MedPage Today) -- Most improvement seen in stage 3 chronic kidney disease (Source: MedPage Today Meeting Coverage)
Source: MedPage Today Meeting Coverage - November 18, 2016 Category: Journals (General) Source Type: news

Reflux and ulcer medications linked to kidney stones and chronic kidney disease
Certain medications commonly used to treat heartburn, acid reflux, and ulcers can have damaging effects on the kidneys. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 18, 2016 Category: Science Source Type: news

Smoking may hinder kidney disease drugs
HealthDay News Cigarette smoking may decrease the effectiveness of drugs taken during early stages of chronic kidney disease, a small study suggests. (Source: Health News - UPI.com)
Source: Health News - UPI.com - November 18, 2016 Category: Consumer Health News Source Type: news

Smoking May Hinder Kidney Disease Drugs
FRIDAY, Nov. 18, 2016 -- Cigarette smoking may decrease the effectiveness of drugs taken during early stages of chronic kidney disease, a small study suggests. Blood pressure-lowering drugs known as angiotensin-converting enzyme inhibitors slow... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 18, 2016 Category: Journals (General) Source Type: news

Reducing salt intake may help protect kidney patients ’ heart and kidney health
New research indicates that reducing sodium intake may provide kidney and heart benefits for patients with chronic kidney disease (CKD). (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 18, 2016 Category: Science Source Type: news

Combo Shows Promise for Hep C Patients With Renal Disease Combo Shows Promise for Hep C Patients With Renal Disease
The combination of glecaprevir plus pibrentasvir is effective and safe for people with any genotype of the hepatitis C virus who have moderate to severe chronic kidney disease, new research shows.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - November 17, 2016 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Researchers discover how to prevent calcification of heart tissue
FINDINGSResearchers at the  Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have discovered that calcification of heart muscle tissue is caused when a type of cell called cardiac fibroblasts go awry. The scientists also found that blocking a molecular pathway in cardiac fibroblasts prevents heart calcification in mice.BACKGROUNDIn bones, cells called osteoblasts create a strong, dense matrix out of calcium and phosphate. Calcification of soft tissues — known as ectopic calcification — is abnormal and occurs with common diseases such as diabetes and chronic kidney disease...
Source: UCLA Newsroom: Health Sciences - November 17, 2016 Category: Universities & Medical Training Source Type: news

Researchers identify pathway important for kidney function
(Boston University Medical Center) Boston University researchers, in collaboration with Centers for Therapeutic Innovation at Pfizer Inc., have discovered a novel molecular pathway needed to regulate kidney podocytes -- special octopus-like cells that are critical in maintaining normal kidney function. The findings, which appear in JCI Insight, may help identify a new drug target for chronic kidney diseases associated with podocyte loss. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 17, 2016 Category: Global & Universal Source Type: news

Wayne State and Henry Ford present findings on ESRD and CKD
(Wayne State University - Office of the Vice President for Research) On Nov. 17, 2016, a Wayne State University doctoral student, Matthew Jasinski, will present results from his dissertation at the Annual Meeting of the American Society of Nephrology in Chicago. The study demonstrates the value of proactive identification of and family psychoeducation about cognitive impairment in patients with End-Stage Renal Disease or Chronic Kidney Disease (ESRD/CKD). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 17, 2016 Category: Global & Universal Source Type: news

Pregnancy in Women With CKD: A Success Story Pregnancy in Women With CKD: A Success Story
Pregnancies among women with chronic kidney disease may come with a high risk of complications, but better management practices have improved maternal and fetal outcomes.American Journal of Kidney Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 15, 2016 Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news

Central Sleep Apnea Tied to Faster Decline in Non-Dialyzed CKD Patients Central Sleep Apnea Tied to Faster Decline in Non-Dialyzed CKD Patients
Central sleep apnea (CSA) is associated with an increased mortality risk in patients with chronic kidney disease (CKD) who are not on dialysis, new research shows.Reuters Health Information (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - November 14, 2016 Category: Intensive Care Tags: Family Medicine/Primary Care News Source Type: news

The More Constipated You Get, The Higher Your Risk For Kidney Disease
In what may not make for the sexiest headline, a new study shows there’s a link between constipation and kidney disease. In the study, researchers examined health records from more than 3.5 million U.S. veterans, looking at whether they reported being constipated or had used laxatives over period of about seven years. They found that those who had experienced constipation had higher risks of developing chronic kidney disease and kidney failure than those who had not. They also found that the more severe the participant’s constipation, the higher their risk of developing these kidney conditions. “We cannot...
Source: Science - The Huffington Post - November 14, 2016 Category: Science Source Type: news

Allopurinol does not increase chronic kidney disease risk in gout patients
(American College of Rheumatology) Allopurinol, a widely used treatment for lowering serum urate levels, does not appear to increase risk of kidney deterioration in gout patients with normal or near-normal kidney function, according to new research findings presented this week at the 2016 ACR/ARHP Annual Meeting in Washington. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 12, 2016 Category: Global & Universal Source Type: news

European Commission Approves Parsabiv ™ (etelcalcetide) For The Treatment Of Secondary Hyperparathyroidism In Adults On Hemodialysis
First Treatment Advance for Secondary Hyperparathyroidism in More Than a Decade and First Intravenous Calcimimetic to Help Healthcare Providers Lower Key Lab Values THOUSAND OAKS, Calif., Nov. 11, 2016 /PRNewswire/ -- Amgen (NASDAQ:AMGN) today announced that the European Commission (EC) has granted marketing authorization for Parsabiv™ (etelcalcetide) for the treatment of secondary hyperparathyroidism (sHPT) in adult patients with chronic kidney disease (CKD) on hemodialysis. Parsabiv is the first calcimimetic agent that can be administered intravenously by a healthcare provider three times a week at the en...
Source: Amgen News Release - November 11, 2016 Category: Pharmaceuticals Tags: Uncategorized Source Type: news

Link between constipation, kidney disease uncovered
Individuals with constipation had a 13% higher likelihood of developing chronic kidney disease and a 9% higher likelihood of developing kidney failure compared with individuals without constipation, report investigators. More severe constipation was linked with an incrementally higher risk for both chronic kidney disease and kidney failure. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 11, 2016 Category: Science Source Type: news

Constipation linked to kidney disease
Constipation linked to 13% higher risk of chronic kidney disease and 9% higher risk of kidney failure Related items fromOnMedica AF associated with more comorbidities than had been thought Guidance hopes to speed up diagnosis of kidney disease Diet for lowering blood pressure also reduces risk of kidney disease Constipation in infants and children (Source: OnMedica Latest News)
Source: OnMedica Latest News - November 10, 2016 Category: UK Health Source Type: news