Kidney failure of unknown cause baffles Sri Lankan doctors
SRI JAYAWARDENEPURA KOTTE, Sri Lanka, March 15 (UPI) -- Doctors in Sri Lanka say an "unknown plague" involving chronic kidney disease of unknown cause is putting families at risk and young people are migrating. (Source: Health News - UPI.com)
Source: Health News - UPI.com - March 15, 2014 Category: Consumer Health News Source Type: news

Chronic Kidney Disease and the Aging PopulationChronic Kidney Disease and the Aging Population
As the general population ages, more people will develop and be at risk for chronic kidney disease. How can clinicians educate the public about the dangers of the disease? Nephrology Dialysis Transplantation (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 14, 2014 Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news

Body's fatty folds may help fight kidney failure
In a new study, it was observed that in rats with kidney disease, functioning of the kidney improved when the organ was fused with the omentum, a fatty fold of tissue that lies close to the kidney and is a rich source of stem cells. The findings suggest that stem cells from a chronic kidney disease patient’s own omentum may help heal diseased kidneys without the need for an outside source of cells. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 13, 2014 Category: Science Source Type: news

La Jolla's GCS-100 Improves Kidney Function In Study
La Jolla Pharmaceutical Co announced positive top-line results from its Phase II trial evaluating GCS-100 for treatment in chronic kidney disease (CKD). The company’s shares rose about 40 percent in extended trading following the news. (Source: Pharmaceutical Online News)
Source: Pharmaceutical Online News - March 13, 2014 Category: Pharmaceuticals Source Type: news

La Jolla Pharma's Drug Improves Kidney Function in TrialLa Jolla Pharma's Drug Improves Kidney Function in Trial
La Jolla Pharmaceutical Co said its lead experimental drug to treat chronic kidney disease met the main goal of improving kidney function in a mid-stage study. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 12, 2014 Category: Consumer Health News Tags: Nephrology News Source Type: news

La Jolla Pharma's drug improves kidney function in trial, shares soar
(Reuters) - La Jolla Pharmaceutical Co said its lead experimental drug to treat chronic kidney disease met the main goal of improving kidney function in a mid-stage study, sending the company's shares up about 40 percent in extended trading. (Source: Reuters: Health)
Source: Reuters: Health - March 10, 2014 Category: Consumer Health News Tags: healthNews Source Type: news

La Jolla Pharma's drug improves kidney function in trial
(Reuters) - La Jolla Pharmaceutical Co said its experimental drug to treat chronic kidney disease met the main goal of improving kidney function in a mid-stage study, sending the company's shares up 28 percent in extended trading. (Source: Reuters: Health)
Source: Reuters: Health - March 10, 2014 Category: Consumer Health News Tags: healthNews Source Type: news

Blood Pressure in CKD: 'The Lower the Better' Still ValidBlood Pressure in CKD: 'The Lower the Better' Still Valid
Despite a recent study to the contrary, Dr. Henry Black doesn't think we should aim for stage 1 hypertension in patients with chronic kidney disease. Medscape Cardiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 6, 2014 Category: Consumer Health News Tags: Cardiology Commentary Source Type: news

Active vitamin D helps remove toxic aluminum in chronic kidney disease patients
(Source: NaturalNews.com)
Source: NaturalNews.com - March 6, 2014 Category: Consumer Health News Source Type: news

Study points to new biological mechanisms, treatment paradigm for kidney disease
Prevention and reversal of chronic kidney disease is an urgent public health need. The disease affects 1 in 10 Americans, is debilitating and deadly, and existing drugs, at best, offer only mild delay in progression to end-stage kidney failure. New research led by Icahn School of Medicine at Mount Sinai investigators has uncovered abnormal molecular signaling pathways from disease initiation to irreversible kidney damage, kidney failure, and death. Results from their preclinical and human research are published online in the Journal of Clinical Investigation. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 5, 2014 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news

AFib Patients with Chronic Kidney Disease Also Benefit from Warfarin (FREE)
By Larry Husten A large observational study, published in JAMA, offers some reassurance that anticoagulation in atrial fibrillation patients who also have chronic kidney disease may be beneficial.Researchers in Sweden analyzed data from … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 5, 2014 Category: Primary Care Source Type: news

Warfarin Benefits Extended To Patients with Chronic Kidney Disease
Anticoagulation is a cornerstone of therapy for atrial fibrillation because it lowers the heightened risk for stroke in this population. People with chronic kidney disease are also at increased risk for stroke, but the benefits of anticoagulation are less clear in this group, and anticoagulation is used less often in AF patients who have CKD. Now, a large observational study offers some reassurance that anticoagulation in AF patients with CKD may be beneficial. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - March 4, 2014 Category: Pharmaceuticals Authors: Larry Husten Source Type: news

Anti-coagulant treatment for atrial fibrillation does not worsen outcomes for patients with kidney disease
Although some research has suggested that the use of the anticoagulant warfarin for atrial fibrillation among patients with chronic kidney disease would increase the risk of death or stroke, a study that included more than 24,000 patients found a lower l-year risk of the combined outcomes of death, heart attack or stroke without a higher risk of bleeding, according to a study in JAMA. Juan Jesus Carrero, Ph.D. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 4, 2014 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news

Warfarin Safe for Kidney Patients with Irregular Heartbeat
Use of the blood thinner may safely ease stroke risk linked to atrial fibrillation, Swedish research finds Source: HealthDay Related MedlinePlus Pages: Blood Thinners, Chronic Kidney Disease (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - March 4, 2014 Category: Consumer Health News Source Type: news

New biological mechanisms, treatment paradigm for kidney disease
Prevention and reversal of chronic kidney disease is an urgent public health need. The disease affects 1 in 10 Americans, is debilitating and deadly, and existing drugs, at best, offer only mild delay in progression to end-stage kidney failure. New research has uncovered abnormal molecular signaling pathways from disease initiation to irreversible kidney damage, kidney failure, and death. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 3, 2014 Category: Science Source Type: news

Mount Sinai study points to new biological mechanisms, treatment paradigm for kidney disease
(The Mount Sinai Hospital / Mount Sinai School of Medicine) Researchers have identified new molecular signaling pathways in chronic kidney disease, pointing to a paradigm shift in treating the disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 3, 2014 Category: Global & Universal Source Type: news

Hemostasis in Chronic Kidney DiseaseHemostasis in Chronic Kidney Disease
How common are bleeding events in patients with impaired renal function receiving anticoagulant treatment, and how important is it for clinicians to carefully prescribe medications in patients with renal impairment? Nephrology Dialysis Transplantation (Source: Medscape Nephrology Headlines)
Source: Medscape Nephrology Headlines - February 28, 2014 Category: Urology & Nephrology Tags: Nephrology Journal Article Source Type: news

Summary of KDIGO 2012 CKD GuidelineSummary of KDIGO 2012 CKD Guideline
What do the latest clinical guidelines say about the pathophysiology of chronic kidney disease, and the best ways to manage and treat it? Kidney International (Source: Medscape Nephrology Headlines)
Source: Medscape Nephrology Headlines - February 27, 2014 Category: Urology & Nephrology Tags: Nephrology Journal Article Source Type: news

March Partner Spotlight
The National Kidney Disease Education Program Showcases NDEP Materials in its Annual Kidney Sundays Event Background The National Kidney Disease Education Program (NKDEP) is a federally sponsored program that works to reduce the burden of chronic kidney disease (CKD) among communities most impacted by the disease. Established in 2000 by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NKDEP aims to raise awareness among people at risk for CKD about the need for testing and educate people with CKD about how to manage their disease...
Source: National Diabetes Education Program - February 27, 2014 Category: Endocrinology Source Type: news

La Jolla completes dosing patients in Phase II study of chronic kidney disease
US-based La Jolla Pharmaceutical has completed dosing in its Phase II clinical study of GCS-100 for the treatment of chronic kidney disease (CKD) and has also collected the final data for assessment of the primary endpoint. (Source: Drug Development Technology)
Source: Drug Development Technology - February 24, 2014 Category: Pharmaceuticals Source Type: news

Many kidney disease patients experience hazardous events related to their medical care
In a study of 267 patients with chronic kidney disease, 69% of participants experienced at least one hazardous event related to their outpatient care. Hypoglycemia (in patients with diabetes) and falling or severe dizziness (in patients without diabetes) were most frequently paired with other complications of medical care. "Disease-specific adverse safety event events are strikingly common in CKD," concludes the lead author. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 21, 2014 Category: Science Source Type: news

Outpatient Care for Kidney Disease May Lead to Complications
Small study found side effects such as low blood sugar, high potassium, severe dizziness Source: HealthDay Related MedlinePlus Pages: Chronic Kidney Disease, Health Facilities, Patient Safety (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - February 20, 2014 Category: Consumer Health News Source Type: news

Velphoro for the Treatment of Hyperphosphatemia in Chronic Kidney Disease Patients on Dialysis
Velphoro (sucroferric oxyhydroxide / PA21) is an iron-based Ca-free phosphate binder for treating Hyperphosphatemia in Chronic Kidney Disease (CKD) patients on dialysis. (Source: Drug Development Technology)
Source: Drug Development Technology - February 14, 2014 Category: Pharmaceuticals Source Type: news

Dialysis Benefits Pregnant Women with Kidney Disease, Study Finds
Longer and more frequent treatments lead to better outcomes Source: HealthDay Related MedlinePlus Pages: Chronic Kidney Disease, Dialysis, Health Problems in Pregnancy (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - February 13, 2014 Category: Consumer Health News Source Type: news

New Guideline Lowers eGFR for Dialysis Start
(MedPage Today) -- New Canadian guidelines suggest that nephrologists can wait to start dialysis in some chronic kidney disease patients until their estimated glomerular filtration rate drops below the 10 to 12 mL/min now commonly used. (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - February 4, 2014 Category: Urology & Nephrology Source Type: news

Musculoskeletal pain linked to high uric acid levels in kidney disease
Chronic musculoskeletal pain is common in patients with chronic kidney disease who are not on dialysis and is particularly associated with hyperuricaemia, say researchers from Taiwan. (Source: MedWire News - Urology)
Source: MedWire News - Urology - February 3, 2014 Category: Urology & Nephrology Source Type: news

This Week in Endo: A New Look at Dialysis
(MedPage Today) -- Canadian guidelines call for a different approach to dialysis for some chronic kidney disease patients. Also, new data on the risk of added sugars. (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - February 2, 2014 Category: Endocrinology Source Type: news

FDA Nixes Wider Use of Iron Therapy
(MedPage Today) -- The FDA has turned down wider use of the iron therapy ferumoxytol (Feraheme), currently limited to use in patients with chronic kidney disease, the drug's manufacturer announced Wednesday. (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - January 22, 2014 Category: American Health Source Type: news

This Week in Endocrinology: FDA Considers CKD Drug
(MedPage Today) -- An impending FDA decision on a drug for chronic kidney disease (CKD) is likely to make headlines. Also, research on temperature regulation in weight loss. (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - January 20, 2014 Category: Endocrinology Source Type: news

QuickStats: Rate* of Ambulatory Care Visits for Chronic Kidney Disease,† by Health-Care Setting — United States, 2001–2002 and 2009–2010
(Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - January 16, 2014 Category: American Health Source Type: news

La Jolla Pharma begins Phase II extension study of kidney drug
US-based La Jolla Pharmaceutical has initiated a Phase II extension trial of GCS-100 for the treatment of patients with chronic kidney disease (CKD). (Source: Drug Development Technology)
Source: Drug Development Technology - January 16, 2014 Category: Pharmaceuticals Source Type: news

Study: Kidney cancer patients preserve kidney function with robot-assisted partial nephrectomy
(Henry Ford Health System) Patients with chronic kidney disease who received robot-assisted partial nephrectomy to treat kidney cancer have minimal loss of kidney function -- a smaller amount even than patients with normal kidney function, according to researchers at Henry Ford Hospital's Vattikuti Urology Institute. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 13, 2014 Category: Cancer & Oncology Source Type: news

Kidney Cells Generated From Stem Cells
(MedPage Today) -- Regenerative medicine researchers have made an important advancement in their quest to grow functional kidneys from stem cells, which could lead to better treatments for patients with chronic kidney disease. (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - January 12, 2014 Category: Urology & Nephrology Source Type: news

Prevalence of depression symptoms and serum levels of interleukin-6 in hemodialysis patients - Knuth B, Radtke V, Rocha P, da Silva KS, Dalsóglio F, Gazal M, Jansen K, Souza DO, Portela LV, Kaster M, Oses JP.
AIM: In hemodialysis patients, depression appears as the most common psychopathological condition. States of advanced chronic kidney disease and dialysis are associated with a state of chronic inflammation. Depression has been linked to activation of the i... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - January 3, 2014 Category: Global & Universal Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Researchers generate kidney tubular cells from stem cells
Researchers have successfully coaxed stem cells to become kidney tubular cells, a significant advance toward one day using regenerative medicine, rather than dialysis and transplantation, to treat kidney failure. The findings are published in the Journal of the American Society of Nephrology (JASN).Chronic kidney disease is a major global public health problem, and when patients progress to kidney failure, their treatment options are limited to dialysis and kidney transplantation. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 30, 2013 Category: Consumer Health News Tags: Stem Cell Research Source Type: news

Treatment of Hepatitis B in Patients With CKDTreatment of Hepatitis B in Patients With CKD
What is the most effective way to treat hepatitis B in patients with chronic kidney disease? Are certain drug therapies and combinations better in this subset of patients? Kidney International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 27, 2013 Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news

Long-held hypothesis that iron promotes atherosclerosis challenged by study
A UCLA research team has found no evidence of an association between iron levels in the body and the risk of atherosclerosis, the hardening and narrowing of the arteries that leads to cardiovascular disease, the No. 1 killer in the U.S.The discovery, based on a comprehensive study in a mouse model of atherosclerosis, contradicts a long-held hypothesis about the role of iron in the disease and carries important implications for patients with chronic kidney disease or anemia related to inflammatory disorders, many of whom receive high-dose iron supplementation therapy. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 23, 2013 Category: Consumer Health News Tags: Heart Disease Source Type: news

US experts say high blood pressure is overtreated
Conclusion These US derived guidelines do not change how doctors in the UK will help care for people with high blood pressure. But they will provide focus for further expert debate on the issue of treating hypertension in this country. As the guideline authors note in their conclusion, the guidance does not change the definition of high blood pressure (140/90mmHg or higher), and that the recommendations are not a substitute for clinical judgement (for example, doctors making treatment decisions based on the overall health of their patient and the patient’s preferences). The guideline authors say decisions about care...
Source: NHS News Feed - December 20, 2013 Category: Consumer Health News Tags: Heart/lungs Medication Source Type: news

Cancer death risk increases with chronic kidney disease
Cancer sufferers are more likely to die from their condition if their kidneys are not functioning properly, a new study published online in the American Journal of Kidney Diseases claims.Dr. Germaine Wong from the University of Sydney led the research, which shows that even mild to moderate reduction in kidney function increased the rate of cancer mortality.According to the National Kidney Foundation, 26 million Americans have kidney disease, but as it does not have symptoms until it is advanced, it often goes undiagnosed. Dr. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 18, 2013 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news

FDA grants approval of a Phase 3 pivotal study for ST10 for the treatment of iron deficiency anaemia in chronic kidney disease
Shield Therapeutics, an independent specialty pharmaceutical company focused on the development of mineral-derived hospital pharmaceuticals, today announces that the US Food and Drug Administration (FDA) has accepted its Investigational New Drug (IND) application to initiate a Phase 3 pivotal study of ST10, its novel oral iron-replacement therapy, for the treatment of iron deficiency anaemia (IDA) in pre-dialysis patients with chronic kidney disease (CKD). (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 18, 2013 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news

Body mass index 'in and of itself' increases risk of developing chronic kidney disease
A new UCSF-led study of nearly 3,000 individuals links obesity to the development of kidney disease. The work also shows that, when properly measured, declines in kidney function are detectable long before the emergence of other obesity-related diseases such as diabetes and high blood pressure.Healthy kidneys are vital to the proper functioning of the heart and brain, as well as the skeletal and immune systems, and the research adds additional urgency to the call for doctors to intervene early in life with obese patients, the researchers said. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 18, 2013 Category: Consumer Health News Tags: Obesity / Weight Loss / Fitness Source Type: news

UCLA study challenges long-held hypothesis that iron promotes atherosclerosis
A UCLA research team has found no evidence of an association between iron levels in the body and the risk of atherosclerosis, the hardening and narrowing of the arteries that leads to cardiovascular disease, the No. 1 killer in the U.S.   The discovery, based on a comprehensive study in a mouse model of atherosclerosis, contradicts a long-held hypothesis about the role of iron in the disease and carries important implications for patients with chronic kidney disease or anemia related to inflammatory disorders, many of whom receive high-dose iron supplementation therapy. The findings currently appear online ...
Source: UCLA Newsroom: Health Sciences - December 17, 2013 Category: Universities & Medical Training Source Type: news

Antihypertensives appear associated with lower risk for dialysis in patients with advanced chronic kidney disease
Patients with stable hypertension and the most advanced stage of chronic kidney disease (CKD) before dialysis appeared to have a lower risk for long-term dialysis or death if they were treated with the antihypertensive drugs known as angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin II receptor blockers (ARBs), according to a study published by JAMA Internal Medicine, a JAMA Network publication. An ACEI or ARB is known to delay the progression of CKD in patients with and without diabetes, particularly in those patients with mild to moderate renal insufficiency. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 17, 2013 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news

Physical activity may slow kidney function decline in patients with kidney disease
Increased physical activity may slow kidney function decline in patients with kidney disease, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). The findings suggest that exercise could have a powerful effect on maintaining patients' health.Approximately 60 million people globally have chronic kidney disease (CKD). In the past 20 years, few new interventions have been shown to be useful in slowing the progression of the disease. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 17, 2013 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news

ACE-Inhibitors and ARBs Associated with Reduced Need for Dialysis in Advanced CKD (FREE)
By Kelly Young Use of either angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) — but not the two together — may reduce the need for dialysis in patients with advanced chronic kidney disease, … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - December 17, 2013 Category: Primary Care Source Type: news

UCLA study challenges long-held hypothesis that iron promotes atherosclerosis
(University of California - Los Angeles Health Sciences) A UCLA research team has found no evidence of an association between iron levels in the body and the risk of atherosclerosis. The discovery, based on a comprehensive study in a mouse model of atherosclerosis, contradicts a long-held hypothesis about the role of iron in the disease and carries important implications for patients with chronic kidney disease or anemia related to inflammatory disorders, many of whom receive high-dose iron supplementation therapy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 17, 2013 Category: Global & Universal Source Type: news

ACE or ARB Each Effective in Advanced Kidney Disease (CME/CE)
(MedPage Today) -- The use of ACE inhibitors or angiotensin receptor blockers (ARBs) in patients with advanced chronic kidney disease and hypertension may have prevented the initiation of long-term dialysis and delayed death, a Taiwanese study showed. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - December 16, 2013 Category: Cardiology Source Type: news

PodMed: A Medical News Roundup From Johns Hopkins (with audio)
(MedPage Today) -- This week's topics include the risk of overdiagnosis of lung cancers with low-dose CT, genotype impact on Coumadin dosing, diabetes and hypoglycemia risk, and cholesterol management in folks with chronic kidney disease. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - December 13, 2013 Category: Cardiology Source Type: news

The Future of NephrologyThe Future of Nephrology
'We need to be truly expert' in managing chronic kidney disease, says Dr. Jeffrey Berns, in order to preserve the specialty of nephrology. Medscape Nephrology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 13, 2013 Category: Consumer Health News Tags: Nephrology Commentary Source Type: news

RAA Inhibitors Tied to Longer Survival With Chronic Kidney DiseaseRAA Inhibitors Tied to Longer Survival With Chronic Kidney Disease
Patients with chronic kidney disease (CKD) who are taking angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) survive longer than those not on the drugs, according to a study of more than 40,000 U.S. veterans. (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 11, 2013 Category: Consumer Health News Tags: Medscape Today News Source Type: news