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Developing a New Score: How Machine Learning Improves Risk Prediction
Composite risk scores have been used for decades to identify disease risk and health status in the general population. However, current approaches often fail to identify people who would benefit from intervention or recommend unnecessary intervention. Machine learning promises to improve accuracy, ensuring targeted treatment for patients that need it and reducing unnecessary intervention. Framingham Risk Score, the gold standard for predicting the likelihood of heart disease, predicts hospitalizations with about 56% accuracy. It uses factors such as age, gender, smoking, cholesterol levels, and systolic blood pre...
Source: MDDI - November 17, 2017 Category: Medical Devices Authors: Heather R. Johnson Tags: R & D Source Type: news

Medical News Today: Coffee makes for a happy liver, says board of experts
We all love coffee, and according to the latest report, your liver loves coffee, too. So, grab your mug, sit back, and we'll explain the details. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 17, 2017 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

Fatty Liver Disease
Fatty Liver (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - November 17, 2017 Category: General Medicine Source Type: news

Beta-blockers and Exercise Testing in Advanced Liver Disease Beta-blockers and Exercise Testing in Advanced Liver Disease
Might beta-blockers alter prognostically relevant measures of cardiopulmonary performance during exercise testing in patients with advanced liver disease?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 17, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Novel material for managing liver disease
EU-funded researchers have developed a carbon with tiny pores that could prevent infection of livers by intestinal bacteria - a common complication in chronic liver disease. The material could improve patients' quality of life and chances of survival, while reducing the use of antibiotics in managing the disease. (Source: EUROPA - Research Information Centre)
Source: EUROPA - Research Information Centre - November 17, 2017 Category: Research Source Type: news

Report suggests association between coffee and up to 70 percent reduced risk of liver disease
(Kaizo) A new roundtable report from the Institute for Scientific Information on Coffee (ISIC) in association with the British Liver Trust, on 'Looking after the liver: coffee, caffeine and lifestyle factors' highlights the potential role of coffee consumption in reducing the risk of liver diseases such as liver cancer and cirrhosis, with some studies reporting risk reduction of up to 70% (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 16, 2017 Category: Cancer & Oncology Source Type: news

Vaccine Shortage Complicates Efforts to Quell Hepatitis A Outbreaks Vaccine Shortage Complicates Efforts to Quell Hepatitis A Outbreaks
San Diego County, battling a deadly outbreak of hepatitis A, is postponing an outreach campaign to provide the second of two inoculations against the contagious liver disease until a national shortage of the vaccine is resolved.Kaiser Health News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 14, 2017 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Psoriasis Tied to Higher Risk of Serious Liver Disease Psoriasis Tied to Higher Risk of Serious Liver Disease
People with chronic inflammatory disorders like psoriasis and rheumatoid arthritis may have an increased risk of developing serious liver damage, a recent study suggests.Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - November 14, 2017 Category: Gastroenterology Tags: Dermatology News Source Type: news

Nanotech, gene editing used to edit cholesterol gene: U.S. study
CHICAGO (Reuters) - U.S. researchers have used nanotechnology plus the powerful CRISPR-Cas9 gene editing tool to turn off a key cholesterol-related gene in mouse liver cells, an advance that could lead to new ways to correct genes that cause high cholesterol and other liver diseases. (Source: Reuters: Health)
Source: Reuters: Health - November 13, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Nonalcoholic fatty liver disease increases risk of liver, colorectal, and breast cancers
(Elsevier) Nonalcoholic fatty liver disease (NAFLD) is one of the more common chronic liver diseases worldwide. It is associated with metabolic syndrome (i.e. insulin resistance and diabetes) and predisposes to cardiovascular disease. In a new study published in the Journal of Hepatology, researchers identified links not only between NAFLD and hepatocellular carcinoma (HCC), which have been well established, but also to cancers outside the liver, including colorectal and breast cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 13, 2017 Category: Cancer & Oncology Source Type: news

Psoriasis tied to higher risk of serious liver disease
(Reuters Health) - People with chronic inflammatory disorders like psoriasis and rheumatoid arthritis may have an increased risk of developing serious liver damage, a recent study suggests. (Source: Reuters: Health)
Source: Reuters: Health - November 10, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Boehringer Ingelheim and MiNA Therapeutics to develop novel treatment approaches for fibrotic liver diseases
Boehringer Ingelheim and MiNA Therapeutics ("MiNA"), a pioneer in RNA activation therapeutics, have signed a collaboration and licensing agreement focused on the development of novel compounds to treat fibrotic liver diseases such as NASH, based on MiNA's small activating RNA ("saRNA") therapeutics platform. (Source: World Pharma News)
Source: World Pharma News - November 9, 2017 Category: Pharmaceuticals Tags: Featured Boehringer Ingelheim Business and Industry Source Type: news

New study identifies targets to lessen the effects of alcoholic liver disease
(Elsevier) Chronic alcohol consumption causes abnormal fat accumulation in liver cells (steatosis) and liver fibrosis, which can lead to hepatitis, cirrhosis, and sometimes liver cancer. A new study in The American Journal of Pathology offers insights into the cellular aging that may trigger excessive fibrosis formation in the liver as well as possible means to inhibit these changes, which may lead to new therapeutic approaches for patients with ALD. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - November 8, 2017 Category: Biology Source Type: news

Coffee May Increase Life Expectancy in Liver Disease Coffee May Increase Life Expectancy in Liver Disease
Steep benefits! The latest data link coffee consumption to decreased morbidity and mortality in liver disease.Medscape Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 7, 2017 Category: Consumer Health News Tags: Gastroenterology Expert Column Source Type: news

What Causes White Nails?
Discussion The nail matrix covers the area of the nail plate, and extends proximally in a crescent moon shape with the edges of the crescent extending proximally and inferiorly toward the underlying bone. The nail matrix is a multilayered epithelium that physiologically produces keratinization and gives rise to the nail plate. The distal matrix forms the lower 2/3s of the nail plate and the proximal matrix forms the upper 1/3 of the nail plate. the thickness of the nail plate is proportion to the matrix’s thickness. The nail plate’s free edge contour follows the shape of the nail’s lunula. Melanocytes occ...
Source: PediatricEducation.org - November 6, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Living with NASH: An Unexpected Diagnosis
As our waistlines thicken and our activity levels decrease, another chronic illness threatens to disturb our comfortable lifestyles. And, because it ’s relatively unknown, diagnosis comes as a shock to patients, who usually associate liver disease with heavy consumption of alcohol.Non-alcoholic steatohepatitis (NASH) is an advanced form of non-alcoholic fatty liver disease (NAFLD), where fat accumulates in the liver. It is most commonly associated with obesity, insulin resistance, metabolic syndrome and/or genetic polymorphisms, and is aggravated by inflammation and fibrosis.  First identified in the 1980s, its ...
Source: EyeForPharma - November 3, 2017 Category: Pharmaceuticals Authors: Mariel Metcalfe Source Type: news

Do you trust your brand of supplements? Researchers found a majority of supplements collected at liver treatment centers were mislabeled
(Natural News) A presentation that was delivered at the 2017 Liver Meeting that was conducted by the American Association for the Research of Liver Diseases in Washington, D.C. showed that the mislabeling of ingredients is a common occurrence in herbal and dietary supplements, especially in bodybuilding and weight loss products. “In looking at those cases,... (Source: NaturalNews.com)
Source: NaturalNews.com - November 3, 2017 Category: Consumer Health News Source Type: news

Psoriasis patients at higher risk for liver disease
Study compares inflammatory illnesses Related items fromOnMedica GPs to get help to boost early detection of liver disease Benefits of exercise training in women with fatty liver disease Psoriasis photo library Rheumatoid arthritis Drug for rheumatoid arthritis appears to have effect on severe eczema (Source: OnMedica Latest News)
Source: OnMedica Latest News - November 3, 2017 Category: UK Health Source Type: news

Probiotics and Omega-3s for Fatty Liver Cut Steatosis Risk Probiotics and Omega-3s for Fatty Liver Cut Steatosis Risk
Preventing and treating nonalcoholic fatty liver disease is a growing challenge, but Ukrainian investigators have successfully translated their promising animal findings to the clinical setting.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 2, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Mallinckrodt acquires pharmaceutical firm for $42 million
Mallinkcrodt plc is acquiring Redwood, California-based Ocera Therapeutics Inc., a pharmaceutical firm focused on developing liver disease treatments, for $42 million in cash. (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - November 2, 2017 Category: American Health Authors: Angela Mueller Source Type: news

Fatty liver disease on the rise in children—from too many sweet treats
(Natural News) A sweetener used in ice cream and soda may cause potentially fatal liver disease, a new study suggests. Researchers have found that high fructose consumption is triggering an early form of fatty liver disease in children, a condition that is normally associated with alcohol consumption, which can lead to cancer, stroke, and heart... (Source: NaturalNews.com)
Source: NaturalNews.com - October 27, 2017 Category: Consumer Health News Source Type: news

Experts Raise Red Flag over Fatty Liver Disease
(MedPage Today) -- Paints gloomy picture for population health, economy (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - October 25, 2017 Category: Endocrinology Source Type: news

Sequana Medical Announces Results of the MOSAIC Trial Data Presented at 2017 AASLD
ZURICH, October 24, 2017 -- (Healthcare Sales & Marketing Network) -- Sequana Medical AG (Sequana Medical), a commercial stage medical device company and an innovator in the management of liver disease, today announced that Prof. Florence Wong, University... Devices Sequana Medical, MOSAIC study, alfapump, ascites (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - October 24, 2017 Category: Pharmaceuticals Source Type: news

Blocking stomach acid may promote chronic liver disease
A new study suggests that some widely used acid reflux (heartburn) medications may worsen chronic liver disease. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - October 23, 2017 Category: Consumer Health News Source Type: news

Primary Care Screening for Fatty Liver Disease Debated Primary Care Screening for Fatty Liver Disease Debated
The use of transient elastography to screen for liver fibrosis in the primary care setting can be effective, preliminary data suggest, but not everyone is convinced.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 23, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Even "healthy people," if they eat sugar, are at risk for heart disease, new study finds
(Natural News) New research reveals that even healthy people who consume a high-sugar diet are prone to heart disease. To reach this conclusion, researchers from the University of Surrey in the United Kingdom examined two groups of men, 11 of whom had a fatty liver or also known as non-alcoholic fatty liver disease (NAFLD), while... (Source: NaturalNews.com)
Source: NaturalNews.com - October 23, 2017 Category: Consumer Health News Source Type: news

NAFLD Increases Risk for Cardiovascular Events in Women NAFLD Increases Risk for Cardiovascular Events in Women
In the general population, women tend to be at lower risk for cardiovascular events than men, but the presence of nonalcoholic fatty liver disease appears to change that, a new study finds.Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 23, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Medical News Today: Daily aspirin could ward off liver cancer
Taking aspirin every day could help to lower the risk of liver cancer for patients infected with hepatitis B, a new study suggests. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 20, 2017 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

Weight Loss in Italy?
One of the women I work with wanted to know about the new diet drug called Belviq. The FDA is always approving a new “miracle” weight-loss pill, only to recall it a few years later. To date, at least 34 diet drugs have been taken off the market. Diet pills cause all kinds of problems — heart attack, stroke and psychiatric disorders. And Belviq isn’t any different. Some of its side effects include suicidal thoughts, a racing heartbeat, hallucinations and more… The European Union banned Belviq. The reason? It causes cancer in animals.  And here’s the real irony… Clinical tri...
Source: Al Sears, MD Natural Remedies - October 19, 2017 Category: Complementary Medicine Authors: Cathy Card Tags: Anti-Aging Source Type: news

Prostate problem? Take 2 nuts
By age 60, you have a 50/50 chance of having a clinically enlarged prostate. And it only gets worse every year. When your prostate isn’t functioning properly, it’s hard to enjoy life. Traditional doctors give you two choices. Go under the knife or you take Big Pharma’s drugs. Either way, you have a good chance of ending up with your manhood on the line… If you have surgery, there’s a big risk you’ll be saying goodbye to your sex life for good. The rate of impotence is a shocking 50 to 60% after prostate surgery.1 Big Pharma’s meds to shrink your prostate are no better. These sy...
Source: Al Sears, MD Natural Remedies - October 19, 2017 Category: Complementary Medicine Authors: Cathy Card Tags: Anti-Aging Source Type: news

Takeda and HemoShear partner to discover new treatments for liver diseases
Japan ’s Takeda Pharmaceutical Company has collaborated with US-based biotechnology company HemoShear Therapeutics to discover and develop new therapeutics for liver diseases, including non-alcoholic steatohepatitis (NASH). (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - October 18, 2017 Category: Pharmaceuticals Source Type: news

Fatty Liver Disease Fastest-growing Reason for Transplants in Young U.S. Adults Fatty Liver Disease Fastest-growing Reason for Transplants in Young U.S. Adults
Nonalcoholic fatty liver disease and its more aggressive form, nonalcoholic steatohepatitis, have become the fastest-growing reasons for liver transplants in young Americans, according to a recent study.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - October 18, 2017 Category: Surgery Tags: Gastroenterology News Source Type: news

Gastric Acid Suppression May Promote Liver Injury
Expansion of intestinal Enterococcus faecalis in mice exacerbates ethanol - induced liver disease (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - October 17, 2017 Category: Cancer & Oncology Tags: Family Medicine, Geriatrics, Gastroenterology, Internal Medicine, Nursing, Oncology, Pathology, Pharmacy, Journal, Source Type: news

Fatty liver disease fastest-growing reason for transplants in young U.S. adults
(Reuters Health) - Nonalcoholic fatty liver disease and its more aggressive form, nonalcoholic steatohepatitis, have become the fastest-growing reasons for liver transplants in young Americans, according to a recent study. (Source: Reuters: Health)
Source: Reuters: Health - October 17, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Another Outbreak Related to the Nation ’s Opioid Crisis: Hepatitis C
Details the increased rates of Hepatitis C and how they correlate to the opioid epidemic by looking at West Virginia, which has the highest rates of overdose deaths and new hepatitis B and C infections in the country. Because those infected with hepatitis often do not display symptoms immediately, the disease can go untreated for years, leading eventually to end-stage liver disease. This is one among many diseases that are rising in the midst of the opioid epidemic, and although there is a treatment for it, for many it is not affordable. (May require subscription to view full article.) (Source: News stories via the Rural Assistance Center)
Source: News stories via the Rural Assistance Center - October 17, 2017 Category: Rural Health Source Type: news

Hep C Treatment Increasingly Feasible in Primary Care Hep C Treatment Increasingly Feasible in Primary Care
Clinically stable patients can be treated in primary care, leaving challenging patients, such as those with advanced liver disease or substance abuse problems, to the specialists, experts say.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 12, 2017 Category: Consumer Health News Tags: Family Medicine/Primary Care News Source Type: news

Progress in Fatty Liver and Pediatric Liver Disease Progress in Fatty Liver and Pediatric Liver Disease
New findings on nonalcoholic steatohepatitis, pediatric liver diseases, hepatitis B, and the microbiome will be among the topics tackled at the upcoming Liver Meeting.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 11, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

The Liver Meeting 2017: American Association for the Study of Liver Diseases (AASLD) The Liver Meeting 2017: American Association for the Study of Liver Diseases (AASLD)
Read clinically focused news coverage of key developments from AASLD 2017Medscape Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 11, 2017 Category: Consumer Health News Tags: Conference Coverage Source Type: news

Ethiopia: Sustaining HBV Intervention Success Stories
[Ethiopian Herald] Viral hepatitis result in a potentially life-threatening inflammation of the liver, which is characterized by complications of liver disease. Specifically, hepatitis B (HBV) and C (HCV) viruses alone cause chronic viral hepatitis which is a major global health problem responsible for 57_per cent of liver cirrhosis and 75_per cent of primary liver cancer cases, respectively. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 11, 2017 Category: African Health Source Type: news

Medical News Today: Liver disease risk may be heightened by gastric acid drugs
A study involving both mice and human participants suggests that common drugs used to reduce gastric acid may increase the risk of chronic liver diseases. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 10, 2017 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

Acid reflux? THESE drugs could be making liver disease worse
ACID reflux drugs could be helping liver disease to develop, new research claims. (Source: Daily Express - Health)
Source: Daily Express - Health - October 10, 2017 Category: Consumer Health News Source Type: news

Common acid reflux medications promote chronic liver disease
(University of California - San Diego) Approximately 10 percent of Americans take a proton pump inhibitor drug to relieve symptoms of frequent heartburn and acid reflux. That percentage can be much higher for people with chronic liver disease. Researchers at University of California San Diego School of Medicine have discovered evidence in mice and humans that these medications alter gut bacteria in a way that promotes three types of chronic liver disease. The study is published Oct. 10 in Nature Communications. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - October 10, 2017 Category: International Medicine & Public Health Source Type: news

Too Much Sugar Can Harm Livers of Even Healthy Men
Study found an unhealthy buildup of fat in the vital organ when men switched to high-sugar diet Source: HealthDay Related MedlinePlus Pages: Carbohydrates, Fatty Liver Disease, Men's Health (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - October 6, 2017 Category: Consumer Health News Source Type: news

Medical News Today: High-sugar diets raise heart disease risk in healthy people
A study finds that a high-sugar diet changes a healthy person's fat metabolism so that it resembles that of someone with non-alcoholic fatty liver disease. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 6, 2017 Category: Consumer Health News Tags: Cardiovascular / Cardiology Source Type: news

Stop Your Body Attacking Itself
Modern medicine has no cure for autoimmune diseases — and, sadly, most doctors don’t understand them. I’m talking about disorders like rheumatoid arthritis, type 1 diabetes, lupus, fibromyalgia, chronic fatigue syndrome, psoriasis, multiple sclerosis (MS) and more. In all, there are about 80 autoimmune diseases affecting organs throughout the body. They occur when your own immune system becomes overactive and attacks your body instead of diseases and foreign invaders. The standard mainstream treatment for most autoimmune disorders relies on Big Pharma drugs that cover up symptoms or suppress your immun...
Source: Al Sears, MD Natural Remedies - October 5, 2017 Category: Complementary Medicine Authors: Al Sears Tags: Anti-Aging Source Type: news

Worse than liquor for your liver
Most people think liver disease only happens to alcoholics. But the truth is that being overweight or obese actually puts you at a much higher risk for liver damage than alcohol. In fact, alcohol contributes to only 6% of liver damage. But obesity contributes to 52% of liver disease. And if you’re obese, you’re 400% more likely to develop liver damage than a normal-weight individual.1 That’s why about 30% of people in America have some form of chronic fatty liver disease. It’s called non-alcoholic fatty liver disease (NAFLD). NAFLD causes painful swelling and scarring of the liver.  And I blame...
Source: Al Sears, MD Natural Remedies - October 5, 2017 Category: Complementary Medicine Authors: Al Sears Tags: Health Weight Loss Source Type: news

5 pounds of THIS in your body?
Did you know that by the time you’re 50, you could have almost five pounds of toxins trapped inside your cells, tissue and organs? For millions of years, we had clean air and pure water. But in the past hundred years, our environment has changed faster than we can evolve with it. We weren’t designed to live in a modern world of manmade chemicals, toxins and pollutants. That’s why purging your body of pollutants is more important today than ever. Environmental toxins have become a major health threat. These toxins have linked with many of today’s chronic diseases including: • Cancer • Di...
Source: Al Sears, MD Natural Remedies - October 5, 2017 Category: Complementary Medicine Authors: Al Sears Tags: Anti-Aging Source Type: news

Sweetener in ice cream is crippling our children's livers
Researchers at Boston's Joslin Diabetes Center found children who consume a lot of fructose and glucose under the age of 13 are at high risk of a potentially fatal liver disease. (Source: the Mail online | Health)
Source: the Mail online | Health - October 5, 2017 Category: Consumer Health News Source Type: news

Too much sugar raises the risk of heart disease
Researchers from the University of Surrey found just 12 weeks of a high-sugar diet increases the amount of fat stored in the liver and makes fat metabolism similar to a liver disease patient. (Source: the Mail online | Health)
Source: the Mail online | Health - October 5, 2017 Category: Consumer Health News Source Type: news

Diabetes diet: Eating THIS could irreversibly HARM liver as well as cause type 2 diabetes
DIABETES is known to be driven by fructose sugar that ’s often added to processed foods. Now new research has found fructose could also cause fatty liver disease. (Source: Daily Express - Health)
Source: Daily Express - Health - October 5, 2017 Category: Consumer Health News Source Type: news