AI plus CT improves liver steatosis assessment
Artificial intelligence (AI) used with contrast-enhanced abdominal CT makes...Read more on AuntMinnie.comRelated Reading: Can AI screen for nonalcoholic fatty liver disease? Ultrasound useful for evaluating liver steatosis MRI offers view of liver fat loss in obese patients Steatosis complicates MR elastography for liver fibrosis AIUM: Can deep learning classify liver fibrosis on US? (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - September 22, 2020 Category: Radiology Source Type: news

MAFLD Is Associated With Severity of Covid-19 MAFLD Is Associated With Severity of Covid-19
Does the co-occurence of metabolic-associated fatty liver disease in patients with COVID-19 increase the risk of severe disease?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 21, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Tiny silicon ultrasound detectors offer high resolution
German researchers have created a new type of silicon-based ultrasound detector...Read more on AuntMinnie.comRelated Reading: Ultrasound shows promise for carpal tunnel diagnosis Review: CEUS bests CT, MRI for liver disease Blood pressure monitor trades compression for ultrasound IMV: COVID-19 cuts ultrasound exam volume by 50% Transcranial ultrasound helps solve COVID-19 mystery (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - September 18, 2020 Category: Radiology Source Type: news

Roche receives positive CHMP opinion for Tecentriq in combination with Avastin for the treatment of people with the most common form of liver cancer
Basel, 18 September 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the European Medicines Agency ’s (EMA) Committee for Medicinal Products for Human Use (CHMP) has recommended the approval of Tecentriq® (atezolizumab) in combination with Avastin® (bevacizumab) for the treatment of adult patients with advanced or unresectable hepatocellular carcinoma (HCC) who have not received prior systemi c therapy. Based on this recommendation, a final decision regarding approval of Tecentriq in combination with Avastin in this disease setting, along with the full details of the approved indication, is expe...
Source: Roche Media News - September 18, 2020 Category: Pharmaceuticals Source Type: news

Roche receives positive CHMP opinion for Tecentriq in combination with Avastin for the treatment of people with the most common form of liver cancer
Basel, 18 September 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the European Medicines Agency ’s (EMA) Committee for Medicinal Products for Human Use (CHMP) has recommended the approval of Tecentriq® (atezolizumab) in combination with Avastin® (bevacizumab) for the treatment of adult patients with advanced or unresectable hepatocellular carcinoma (HCC) who have not received prior systemi c therapy. Based on this recommendation, a final decision regarding approval of Tecentriq in combination with Avastin in this disease setting, along with the full details of the approved indication, is expe...
Source: Roche Investor Update - September 18, 2020 Category: Pharmaceuticals Source Type: news

CNIC researchers discover a mechanism allowing immune cells to regulate obesity
(Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)) A CNIC's team have discovered a mechanism explaining how macrophages regulate obesity. The results published in Nature Metabolism could be useful to design new treatments for the obese and overweight, and for some associated pathologies, including fatty liver disease and type 2 diabetes. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - September 17, 2020 Category: International Medicine & Public Health Source Type: news

Ultrasound shows promise for carpal tunnel diagnosis
Ultrasound imaging shows promise as a painless way to diagnose carpal tunnel...Read more on AuntMinnie.comRelated Reading: Review: CEUS bests CT, MRI for liver disease Lung ultrasound helps physicians manage COVID-19 Blood pressure monitor trades compression for ultrasound IMV: COVID-19 cuts ultrasound exam volume by 50% EAN 2017: Smartphone use can damage median nerve (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - September 16, 2020 Category: Radiology Source Type: news

Review: CEUS bests CT, MRI for liver disease
Contrast-enhanced ultrasound (CEUS) is a promising tool to diagnose some forms...Read more on AuntMinnie.comRelated Reading: PET/MRI ups lesion detection by 15% for some cancers AI boosts MRI's performance for detecting liver lesions Ultrasound software predicts cancer treatment success Deep learning detects HCC on contrast-enhanced MRI MRI identifies biomarkers for aggressive HCC subtype (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - September 15, 2020 Category: Radiology Source Type: news

How high fructose intake may trigger fatty liver disease
A study suggested that consuming high amounts of fructose may promote non-alcoholic fatty liver disease by damaging the intestinal barrier. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - September 15, 2020 Category: Consumer Health News Source Type: news

New Approach Allows Safe Transplant of Kidneys Tainted by Hepatitis C
TUESDAY, Sept. 8, 2020 -- New hepatitis C medications are allowing people to receive a kidney transplant from a deceased donor who had the liver disease -- a strategy aimed at getting more lifesaving organs to patients languishing on waitlists. Two... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - September 8, 2020 Category: General Medicine Source Type: news

Vitamin C and thiamine are associated with lower mortality in sepsis
BACKGROUND The efficacy of vitamin C (VitC) and thiamine (THMN) in patients admitted to the intensive care unit (ICU) with sepsis is unclear. The purpose of this study was to evaluate the effect of VitC and THMN on mortality and lactate clearance in ICU patients. We hypothesized that survival and lactate clearance would be improved when treated with thiamine and/or VitC. METHODS The Philips eICU database version 2.0 was queried for patients admitted to the ICU in 2014 to 2015 for 48 hours or longer and patients with sepsis and an elevated lactate of 2.0 mmol/L or greater. Subjects were categorized according to the receipt ...
Source: Current Awareness Service for Health (CASH) - September 3, 2020 Category: Consumer Health News Source Type: news

Rates, predictors, and mortality of sepsis-associated acute kidney injury: A systematic review and meta-analysis
Conclusion(s): Risk factors of S-AKI arise from a wide range of sources, making it difficult to predict and prevent this condition. Comorbidities, and certain drugs, are the main risk factors for S-AKI. Our review can provide guidance on the application of interventions to reduce the risks associated with sepsis-associated acute kidney injury and can also be used to tailor patient-specific treatment plans and management strategies in clinical practice. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 3, 2020 Category: Consumer Health News Source Type: news

Researchers find molecular link between liver disease, insulin resistance
Yale researchers have zeroed in on a molecular link between nonalcoholic fatty liver disease and liver insulin resistance in type 2 diabetes. (Source: Yale Science and Health News)
Source: Yale Science and Health News - September 2, 2020 Category: Universities & Medical Training Source Type: news

fMRI shows how 'one day at a time' works for alcoholics
Functional MRI (fMRI) shows how the Alcoholics Anonymous mantra "one day at...Read more on AuntMinnie.comRelated Reading: New MRI contrast material promises earlier liver diagnosis Ultrasound identifies alcohol-induced liver disease PET, fMRI find beer reflex in brain Brain MRI reveals how AA prayers work (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - September 1, 2020 Category: Radiology Source Type: news

Mirum Pharmaceuticals Initiates Rolling Submission of a New Drug Application for Maralixibat for the Treatment of Cholestatic Pruritus in Patients with Alagille Syndrome and Launches Expanded Access Program
FOSTER CITY, Calif.--(BUSINESS WIRE)--Sep. 1, 2020-- Mirum Pharmaceuticals, Inc. (Nasdaq: MIRM), a biopharmaceutical company focused on the development and commercialization of novel therapies for debilitating liver diseases today... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - September 1, 2020 Category: Drugs & Pharmacology Source Type: news

Alcoholic Liver Disease Death Rates Up for Non - Hispanic Whites
Death rates higher for men, but male - to - female ratio decreased in past two decades (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - August 27, 2020 Category: Psychiatry Tags: Family Medicine, Gastroenterology, Gynecology, Internal Medicine, Psychiatry, Journal, Source Type: news

Alcoholic Liver Disease Death Rates Up for Non-Hispanic Whites
THURSDAY, Aug. 27, 2020 -- There is considerable racial and ethnic disparity in alcoholic liver disease mortality, and although men have higher death rates, the male-to-female ratios decreased in the past two decades, according to a study published... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 27, 2020 Category: Pharmaceuticals Source Type: news

Premature deaths from alcoholic liver disease rising as gap between men and women narrows
(Elsevier) A new study in the American Journal of Preventive Medicine identifies emerging patterns in the rate of and age at premature death from alcoholic (alcohol-associated) liver disease (ALD) in the US over the last two decades. Significantly, the study documents that since the early 2000s, ALD death rates among non-Hispanic whites, particularly women, have increased more rapidly than rates among non-Hispanic blacks. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - August 27, 2020 Category: International Medicine & Public Health Source Type: news

Menopause may increase risk for non-alcoholic fatty liver disease
Postmenopausal women may be more likely to develop non-alcoholic fatty liver disease due to a reduction in sex hormones, suggests a study published in Endocrinology.News Medical (Source: Society for Endocrinology)
Source: Society for Endocrinology - August 26, 2020 Category: Endocrinology Source Type: news

New insights into mechanism of therapy to reduce liver fat and prevent fibrosis
(Massachusetts General Hospital) A team led by researchers at Massachusetts General Hospital (MGH) has taken an important step forward in the goal of developing a potential treatment for non-alcoholic fatty liver disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 26, 2020 Category: International Medicine & Public Health Source Type: news

Changes in gut microbiota can greatly impact alcohol-related liver disease and cancer risk
(Spink Health) Digital ILC 2020: Studies evaluating fecal microbial transplant and inflammatory signalling highlight the significance of gut microflora in alcohol-related liver disease and hepatocarcinogenesis (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 26, 2020 Category: Cancer & Oncology Source Type: news

Repeat FIB-4 Blood Tests Help Predict Cirrhosis Repeat FIB-4 Blood Tests Help Predict Cirrhosis
The difference between one fibrosis-4 (FIB-4) score and the next can predict risk for severe liver disease, new research shows, and can provide useful information to primary care doctors.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 25, 2020 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Blood Test Can Spot Patients With NASH at Risk for Liver Disease Blood Test Can Spot Patients With NASH at Risk for Liver Disease
A blood test can identify patients with non-alcoholic steatohepatitis (NASH) and significant fibrosis who are at risk for progressive liver disease, new research indicates.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - August 24, 2020 Category: Pathology Tags: Gastroenterology News Source Type: news

Liver Manifestations and Outcomes in COVID-19 Liver Manifestations and Outcomes in COVID-19
What have we learned about the impact of COVID-19 on liver function, both in patients with and without existing liver disease?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 24, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Excessive fructose consumption may cause a leaky gut, leading to fatty liver disease
(University of California - San Diego) Researchers at University of California San Diego School of Medicine report that fructose only adversely affects the liver after it reaches the intestines, where the sugar disrupts the epithelial barrier protecting internal organs from bacterial toxins in the gut (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 24, 2020 Category: International Medicine & Public Health Source Type: news

Peer support groups helps mum of child with a rare liver disease find answers and support
After her daughter's PFIC diagnosis, Claire Brinkley searched for a way to connect with other parents with similar experiences and questions.   (Source: mobihealthnews)
Source: mobihealthnews - August 21, 2020 Category: Information Technology Source Type: news

Peer support groups help mum of child with a rare liver disease find answers and support
After her daughter's PFIC diagnosis, Claire Brinkley searched for a way to connect with other parents with similar experiences and questions.   (Source: mobihealthnews)
Source: mobihealthnews - August 21, 2020 Category: Information Technology Source Type: news

Strides Pharma gets USFDA nod for Ursodiol tablets, a liver disease treatment drug
Strides Pharma Science gets an approval from the USFDA to market Ursodiol tablets used for treating primary biliary cirrhosis, a progressive disease of the liver caused by a buildup of bile within the liver. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - August 21, 2020 Category: Pharmaceuticals Source Type: news

Liver Disease Common After Fontan Procedure Liver Disease Common After Fontan Procedure
Most patients will develop liver fibrosis after their Fontan procedure, and many will require heart-liver transplants, according to a new review.Reuters Health Information (Source: Medscape Radiology Headlines)
Source: Medscape Radiology Headlines - August 20, 2020 Category: Radiology Tags: Gastroenterology News Source Type: news

TGen review suggests postmenopausal women at risk for nonalcoholic fatty liver disease
(The Translational Genomics Research Institute) NAFLD is the most common cause of liver damage, and can lead to liver cirrhosis and death. It affects nearly 1 in 4 people across the globe. It often is associated with obesity, abnormally high amounts of lipids in the blood, and type 2 diabetes. In the US, the number of NAFLD cases is expected to grow to more than 100 million within the next decade, annually costing an estimated at $292 billion. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 14, 2020 Category: International Medicine & Public Health Source Type: news

NAFLD May Predict Arrhythmia Recurrence Post-AF Ablation NAFLD May Predict Arrhythmia Recurrence Post-AF Ablation
The presence of nonalcoholic fatty liver disease adds a further modifiable target for preablation medical optimization, researchers say.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - August 14, 2020 Category: Cardiology Tags: Cardiology News Source Type: news

Strong link found between abnormal liver tests and poor COVID-19 outcomes
In new Yale research, the correlation between COVID-19 hospitalization and liver disease was found to be stronger than previously observed. (Source: Yale Science and Health News)
Source: Yale Science and Health News - August 6, 2020 Category: Universities & Medical Training Source Type: news

Study to explore whether new therapy can help address problem drinking
(University of Plymouth) A psychological therapy found to be effective in helping people achieve and maintain weight loss is being trialled to see if it can support patients with chronic liver disease to stop drinking. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - August 4, 2020 Category: International Medicine & Public Health Source Type: news

Fatty liver disease despite a normal weight
(University of Tsukuba) Researchers from the University of Tsukuba found significant differences in the clinical presentation of non-obese patients with non-alcoholic fatty liver disease (NAFLD) based on their sex and body mass index. They found that non-obese NAFLD patients had lower muscle mass and strength (pre-sarcopenia) compared to obese NAFLD patients. Further, fat accumulation in muscles was more common among women. These findings help us understand the clinical presentation of NAFLD. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 3, 2020 Category: International Medicine & Public Health Source Type: news

Insight on novel genetic approaches to metabolic liver diseases
(Wayne State University - Office of the Vice President for Research) Faculty from Wayne State University's Eugene Applebaum College of Pharmacy and Health Sciences are leading a team of researchers to understand the causal relationships between diabetes, obesity and nonalcoholic fatty liver disease in hopes of developing a treatment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 31, 2020 Category: International Medicine & Public Health Source Type: news

Aerobic exercise could have the final say on fatty livers
(Trinity College Dublin) Trinity College Dublin study is the first to demonstrate significant improvements in biopsy-measured liver outcomes in a metabolic associated fat liver disease (MAFLD) cohort following an exercise-only intervention, without clinically significant weight loss. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 29, 2020 Category: Biology Source Type: news

Want to boost your zinc levels? Eat more of these nutrient-rich foods
(Natural News) When you follow a balanced diet, you ensure that your body is getting all the essential vitamins and minerals it needs, such as zinc. Research suggests that being deficient in zinc leads to a lot of health problems, such as immune dysfunction and chronic kidney and liver disease. To prevent zinc deficiency, incorporate foods rich... (Source: NaturalNews.com)
Source: NaturalNews.com - July 27, 2020 Category: Consumer Health News Source Type: news

COVID-19 and Liver Disease--What We Know COVID-19 and Liver Disease--What We Know
This review summarizes changes in liver function observed during SARS-CoV-2 infection. What impact does COVID-19 have on patients with underlying chronic liver disease?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 20, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Limp handshake? You may be at risk of a potentially fatal liver disease
While social distancing means it's currently barred, new research has revealed that a limp handshake or a weak grip could be an early warning sign of non-alcoholic fatty liver disease. (Source: the Mail online | Health)
Source: the Mail online | Health - July 14, 2020 Category: Consumer Health News Source Type: news

Doctors call fatty liver disease a growing public health concern in Canada
Doctors are warning that soaring rates of a common, but often undetected, liver disease could impose an enormous burden on Canadian health care over the next decade if there isn't more public awareness. (Source: CBC | Health)
Source: CBC | Health - July 13, 2020 Category: Consumer Health News Tags: News/Health Source Type: news

In race to defeat fatty liver disease, Peninsula biotech lines up next clinical trial
In the race to find a drug for the fatty liver disease NASH, George Kemble isn ’t dissuaded by Sagimet Biosciences’ size; it’s the data that count. And after pivots by the San Mateo company that Kemble heads, it has promising early data back from a mid-stage study of its drug targeting nonalcoholic steatohepatitis, or NASH, and plans to take the drug into another mid-st age study early next year. The Phase II study results come as larger companies have released promising data of their own.… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - July 11, 2020 Category: Pharmaceuticals Authors: Ron Leuty Source Type: news

In race to defeat fatty liver disease, Peninsula biotech lines up next clinical trial
In the race to find a drug for the fatty liver disease NASH, George Kemble isn ’t dissuaded by Sagimet Biosciences’ size; it’s the data that count. And after pivots by the San Mateo company that Kemble heads, it has promising early data back from a mid-stage study of its drug targeting nonalcoholic steatohepatitis, or NASH, and plans to take the drug into another mid-st age study early next year. The Phase II study results come as larger companies have released promising data of their own.… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - July 11, 2020 Category: Biotechnology Authors: Ron Leuty Source Type: news

Sobering reminder about liver disease
(Flinders University) Alcohol's popularity and its central place in socialising in Australia obscures the dangers of excessive drinking and possible liver disease, Flinders University experts warn. As Dry July awareness month highlights the various health risks, the Head of Hepatology and Liver Transplantation at Flinders Medical Centre Associate Professor Alan Wigg says alcohol misuse remains a major health challenge in Australia as seen by high in rates of life-threatening liver disease. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - July 10, 2020 Category: International Medicine & Public Health Source Type: news

Guidance on Managing Liver Dysfunction During COVID-19 Pandemic Guidance on Managing Liver Dysfunction During COVID-19 Pandemic
Patients with COVID-19 may develop abnormal liver function and it's important to consider the potential impact of COVID-19 on the liver, especially in the Asia-Pacific region where chronic liver diseases are prevalent, say the authors of a position statement.Reuters Health Information (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - July 9, 2020 Category: Intensive Care Tags: Infectious Diseases News Source Type: news

Researchers find promising therapy to fight epidemic of liver disease
(University of Colorado Anschutz Medical Campus) In an effort to combat a growing worldwide epidemic of Nonalcoholic Fatty Liver Disease (NAFLD), scientists have discovered a new target and a new therapy that has shown promising results in preclinical mouse models, according to researchers at the University of Colorado Anschutz Medical Campus. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 8, 2020 Category: Biology Source Type: news

U of SC: How non-alcoholic fatty liver disease causes Alzheimer's-like neuroinflammation
(University of South Carolina) Research from UofSC associate professor Saurabh Chatterjee's laboratory in Environmental Health Sciences at the Arnold School of Public Health has revealed the cause behind the previously established link between non-alcoholic fatty liver disease and neurological problems. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 6, 2020 Category: International Medicine & Public Health Source Type: news

Blood tests can predict the risk of liver cirrhosis
(Karolinska Institutet) Repeated measurements of the biomarker FIB-4 in the blood every few years can predict the risk of developing severe liver disease, according to a new study from Karolinska Institutet in Sweden published in the Journal of Hepatology. The risk of liver cirrhosis increases if the levels of this biomarker rise between two testing occasions. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 2, 2020 Category: International Medicine & Public Health Source Type: news

Giant leap in diagnosing liver disease
(Salk Institute) A collaborative team of Salk Institute and UC San Diego scientists have created a novel microbiome-based diagnostic tool that, with the accuracy of the best physicians, quickly and inexpensively identifies liver fibrosis and cirrhosis over 90 percent of the time in human patients. The non-invasive method relies on an algorithm to analyze patient stool samples--which contains traces of what lives in the gut--and could lead to improved patient care and treatment outcomes for liver disease. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 1, 2020 Category: Cancer & Oncology Source Type: news

Curb the symptoms of non-alcoholic fatty liver disease by adopting a Mediterranean diet
(Natural News) Multiple studies have found that eating more fish and plant-based foods like fruits, vegetables and whole grains — typical components of the Mediterranean diet — contribute to good health even in old age. According to Harvard Medical School researchers, people who stick to a Mediterranean diet have a 46 percent higher chance of healthy... (Source: NaturalNews.com)
Source: NaturalNews.com - June 26, 2020 Category: Consumer Health News Source Type: news