Currently prescribed drugs in the UK that could upregulate or downregulate ACE2 in COVID-19 disease: a systematic review, BMJ Open
Conclusions: There is an abundance of the academic literature and media reports on the potential of drugs that could attenuate or exacerbate COVID-19 disease. This is leading to trials of repurposed drugs and uncertainty among patients and clinicians concerning continuation or cessation of prescribed medications. Our review indicates that the impact of currently prescribed drugs on ACE2 has been poorly studied in vivo, particularly in human lungs where the SARS-CoV-2 virus appears to enact its pathogenic effects. We found no convincing evidence to justify starting or stopping currently prescribed drugs to influence outcome...
Source: Current Awareness Service for Health (CASH) - September 24, 2020 Category: Consumer Health News Source Type: news

Cardiology 1995: The Rise of Stents and Statins Cardiology 1995: The Rise of Stents and Statins
To commemorate Medscape's quarter century, we are reposting this celebration of cardiology. What advances in the field have impressed you over the past 25 years?theheart.org on Medscape (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 23, 2020 Category: Consumer Health News Tags: Cardiology Article Source Type: news

Statins reduce COVID-19 severity, likely by removing cholesterol that virus uses to infect
(University of California - San Diego) Analyzing anonymized patient medical records, UC San Diego researchers discovered that cholesterol-lowering statins reduced risk of severe COVID-19 infection, while lab experiments uncovered a cellular mechanism that helps explain why. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 23, 2020 Category: International Medicine & Public Health Source Type: news

Information by Drug Class
FDA provides consumers and industry with safety, regulatory and availability information for various drugs by drug class. From A to Z. Topics include: acetaminophen, estrogen, insulin, opioids, statins, and weight-loss drugs. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - September 22, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

For Older People, Reassuring News in the Statin Debate
There is accumulating evidence that the benefits of statins far outweigh possible risks, and nearly all statins on the market are now available as inexpensive generics. (Source: NYT Health)
Source: NYT Health - September 21, 2020 Category: Consumer Health News Authors: Jane E. Brody Tags: Cholesterol Statins (Cholesterol-Lowering Drugs) Heart Elderly Drugs (Pharmaceuticals) Source Type: news

“Effect of local application of simvastatin in bone regeneration of peri-apical defects-a clinico-radiographic study
ConclusionIntragroup analysis of CBCT- Periapical Index (PAI) scores at 6th and 12th month revealed a significant change in the SIM group (p  = 0.018 and 0.001 respectively), compared to PRF (p = 0.026 and 0.001 respectively) and HA (p = 0.053 and 0.039 respectively). Intergroup analysis of change in the level of CBCT-PAI score was highly significant (p = 0.003).SIM caused a more considerable change in the level of CBCT-PAI score compared to other groups, thereby indicating a faster rate of bone regeneration. (Source: Dental Technology Blog)
Source: Dental Technology Blog - September 19, 2020 Category: Dentistry Source Type: news

Three-drug combo reduces risk for lung cancer by 17%, study finds
Taking aspirin, statins and the drug metformin together reduces the risk for lung cancer by 17%, a study published Thursday by the Journal of Thoracic Oncology found. (Source: Health News - UPI.com)
Source: Health News - UPI.com - September 17, 2020 Category: Consumer Health News Source Type: news

Three common medications lower risk and mortality for lung cancer
(International Association for the Study of Lung Cancer) Combined use of aspirin, statins, and metformin is associated with decreased lung cancerincidence and mortality, according to a study published in the Journal of Thoracic Oncology (JTO). The JTO is the official journal of the International Association for the Study of Lung Cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - September 17, 2020 Category: Cancer & Oncology Source Type: news

Lower heart attack and stroke risk by increasing your intake of this essential vitamin
(Natural News) Heart disease is one of the major causes of death worldwide. It puts a person at risk of heart attack and stroke, which can leave survivors disabled for the rest of their lives. There are drugs used to treat heart disease, such as statins. But these medications often come with side effects and are... (Source: NaturalNews.com)
Source: NaturalNews.com - September 16, 2020 Category: Consumer Health News Source Type: news

Statins Going Generic Saved Medicare Billions
Statins are the most popular type of cholesterol-lowering drug in the United States, prescribed to more than 35 million people. (Source: WebMD Health)
Source: WebMD Health - September 15, 2020 Category: Consumer Health News Source Type: news

Statins Going Generic Saved Medicare Billions
Title: Statins Going Generic Saved Medicare BillionsCategory: Health NewsCreated: 9/14/2020 12:00:00 AMLast Editorial Review: 9/15/2020 12:00:00 AM (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - September 15, 2020 Category: Cardiology Source Type: news

Statins Going Generic Saved Medicare Billions
MONDAY, Sept. 14, 2020 -- Here's evidence that prescription drugs don't have to cost a fortune: New research finds Medicare saved billions as more generic cholesterol-lowering medications became available, even though the number of Americans using... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - September 14, 2020 Category: General Medicine Source Type: news

Statin Use is Associated With Insulin Resistance Statin Use is Associated With Insulin Resistance
Statins are commonly used cholesterol-lowering drugs, but might they be linked to an increased incidence of insulin resistance?Journal of the Endocrine Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 2, 2020 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

COVID-19 Update: Statins and Mortality, Value of Imperfect Tests COVID-19 Update: Statins and Mortality, Value of Imperfect Tests
These are the coronavirus stories you need to know about today.Medscape Medical News (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - August 29, 2020 Category: Internal Medicine Tags: Infectious Diseases News Source Type: news

Statins Linked to Reduced Mortality in COVID-19 Statins Linked to Reduced Mortality in COVID-19
A pooled analysis of available data suggest moderate-to-high intensity statin therapy may be beneficial in patients with COVID-19, researchers say.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - August 28, 2020 Category: Cardiology Tags: Cardiology News Source Type: news

Most Younger MI Patients Wouldn't Get Statins Under Guidelines Most Younger MI Patients Wouldn't Get Statins Under Guidelines
' The classic approach we've taken to identifying young adults for prevention is inadequate in younger adults,'said the author of a new study.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - August 5, 2020 Category: Cardiology Tags: Diabetes & Endocrinology News Source Type: news

Study Casts Doubt on Value of Cholesterol Drugs
TUESDAY, Aug. 4, 2020 -- Hundreds of millions of people worldwide take cholesterol-lowering drugs, like statins, but now a new review suggests that many folks don't benefit from these medications. The researchers said the review of 35 randomized... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - August 4, 2020 Category: General Medicine Source Type: news

Research news tip sheet: Story ideas from Johns Hopkins Medicine
(Johns Hopkins Medicine) Within a month following a heart attack, people are at increased risk for a second one. As a result, physicians treat these patients with medications to rapidly reduce cardiovascular risk factors for another event. Although statins are designed to reduce the risk from one underlying problem, low-density lipoprotein (LDL) or " bad " cholesterol, they often aren't able drop it to recommended levels within 30 days. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 4, 2020 Category: International Medicine & Public Health Source Type: news

Statins are not effective at cutting risk of dying from heart disease
The research, published in the British Medical Journal, found that three quarters of all trials reported no reduction in mortality among those who took drugs to lower their cholesterol. (Source: the Mail online | Health)
Source: the Mail online | Health - August 4, 2020 Category: Consumer Health News Source Type: news

In Rare Cases, Diabetes & Cholesterol Drug Combo Could Be Toxic
MONDAY, Aug. 3, 2020 -- Taking the statin Crestor in combination with the diabetes drug canagliflozin (Invokana) may have the potential to trigger statin toxicity, a new case report suggests. Although this report details the problem in just one... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - August 3, 2020 Category: General Medicine Source Type: news

Statins Increase Lp(a) Plasma Level Statins Increase Lp(a) Plasma Level
A recent study demonstrated that statin therapy increases lipoprotein(a) levels, but whether this increases cardiovascular risk remains to be determined.European Heart Journal (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 24, 2020 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

Statins are a SCAM: International study confirms cholesterol does NOT predict heart disease
(Natural News) If you’ve been trying to keep your cholesterol down in hopes of avoiding a heart attack, you might be barking up the wrong tree. That’s because an international study has shown that LDL cholesterol does not actually predict a person’s risk of heart disease after all. This also means that the statin drugs... (Source: NaturalNews.com)
Source: NaturalNews.com - July 14, 2020 Category: Consumer Health News Source Type: news

Jul 10 2020 This Week in Cardiology Jul 10 2020 This Week in Cardiology
COVID, sacubitril/valsartan, left atrial appendage occlusion, and statins are the topics Dr John Mandrola discusses in this week ’ s podcast.theheart.org on Medscape (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - July 10, 2020 Category: Cardiology Tags: Cardiology Commentary Source Type: news

Primary Prevention Statins Cut Mortality Even in the Very Elderly Primary Prevention Statins Cut Mortality Even in the Very Elderly
With trial data for this age group in short supply, a US veterans cohort study saw a 25% drop in all-cause mortality for those newly starting on a statin at age 75 or older.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - July 9, 2020 Category: Cardiology Tags: Cardiology News Source Type: news

75 or Older? Statins Can Still Benefit Your Heart
People 75 and older who were free of heart disease and prescribed a statin wound up with a 25% lower risk of death from any cause and a 20% lower risk of heart-related death, researchers reported July 7 in the Journal of the American Medical Association. (Source: WebMD Health)
Source: WebMD Health - July 9, 2020 Category: Consumer Health News Source Type: news

Statin Use May Cut All-Cause, CVD Mortality in Those 75 and Older
WEDNESDAY, July 8, 2020 -- In U.S. veterans aged 75 years and older, statin use is associated with reduced all-cause and cardiovascular mortality, according to a study published in the July 7 issue of the Journal of the American Medical... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 8, 2020 Category: Pharmaceuticals Source Type: news

75 or Older? Statins Can Still Benefit Your Heart
Title: 75 or Older? Statins Can Still Benefit Your HeartCategory: Health NewsCreated: 7/7/2020 12:00:00 AMLast Editorial Review: 7/8/2020 12:00:00 AM (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - July 8, 2020 Category: Cardiology Source Type: news

Statins cut heart attack, stroke risk even in older adults, study says
Older adults can reduce their risk for a fatal heart attack or stroke by 20 percent by taking a statin. Those over age 75 who were newly prescribed cholesterol-lowering drugs were 25 percent less likely to die. (Source: Health News - UPI.com)
Source: Health News - UPI.com - July 7, 2020 Category: Consumer Health News Source Type: news

75 or Older? Statins Can Still Benefit Your Heart
TUESDAY, July 7, 2020 -- Older adults with healthy hearts probably would benefit from taking a cholesterol-lowering statin, a new study contends. People 75 and older who were free of heart disease and prescribed a statin wound up with a 25% lower... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - July 7, 2020 Category: General Medicine Source Type: news

Among Older Adults, Statin Use Tied to Decreased Risk of Death
In a retrospective analysis of U.S. veterans 75 years or older, researchers found those who were prescribed statins had a 25 percent lower risk of death than their counterparts (Source: BWH News)
Source: BWH News - July 7, 2020 Category: Hospital Management Source Type: news

Association between statin use and balance in older adults - Langeard A, Saillant K, Charlebois Cloutier E, Gayda M, Lesage F, Nigam A, Bherer L, Fraser SA.
BACKGROUND: Several medications have been associated with an increased risk of balance deficits and greater likelihood to sustain a fall, representing a large health and economic issue. Statins are regularly prescribed to prevent strokes and heart attacks,... (Source: SafetyLit)
Source: SafetyLit - July 6, 2020 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

Cardiovascular Risk After Sepsis: Understanding the Role of Statin Indications and the Impact of Clinical Inertia on Prescribing Patterns
Conclusion(s): There is a high risk of MACE after sepsis especially among those in statin indicated groups with significant clinical inertia in prescribing practices. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - July 1, 2020 Category: Consumer Health News Source Type: news

Statin use and fall-related hospitalizations among residents of long-term care facilities: a case-control study - Wang KN, Bell JS, Tan EC, Gilmartin-Thomas JF, Dooley MJ, Ilom äki J.
The objective of the study is t... (Source: SafetyLit)
Source: SafetyLit - June 30, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Coronavirus: Could statins reduce risk of death?
Doctors are desperate for more weapons in their arsenal to treat Covid-19, which has killed almost 500,000 people worldwide in just six months. Only one drug has been proven to work so far. (Source: the Mail online | Health)
Source: the Mail online | Health - June 26, 2020 Category: Consumer Health News Source Type: news

Twitter data research reveals more about what patients think about statins
(University of York) More than one in seven people taking statins -- prescribed to lower cholesterol levels -- believed that meant they could still eat unhealthy foods, a new study shows. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 25, 2020 Category: International Medicine & Public Health Source Type: news

Statin use is linked to lower death rate in hospitalized COVID-19 patients
(Cell Press) The use of cholesterol-lowering drugs called statins is associated with a lower death rate and a lower incidence of mechanical ventilation in patients hospitalized with Coronavirus disease 2019 (COVID-19), researchers report June 24 in Cell Metabolism. The large-scale retrospective study also showed that mortality risk and other negative outcomes were not increased by combination therapy consisting of statins and blood pressure-lowering drugs called angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs). (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 24, 2020 Category: Infectious Diseases Source Type: news

Should nursing home residents nearing the end of life continue taking statins?
(American Geriatrics Society) A team of researchers conducted a study to learn more about statin use among older adults, especially those nearing the end of their lives. The study, published in the Journal of the American Geriatrics Society, evaluated statin use by people with life-limiting conditions across nearly all U.S. nursing homes. The researchers hoped to identify statin use among nursing home residents who were unlikely to benefit from treatment. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 24, 2020 Category: International Medicine & Public Health Source Type: news

Statins Tied to Significantly Lower Death Rate From Ovarian Cancer
Title: Statins Tied to Significantly Lower Death Rate From Ovarian CancerCategory: Health NewsCreated: 6/22/2020 12:00:00 AMLast Editorial Review: 6/23/2020 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - June 23, 2020 Category: Cancer & Oncology Source Type: news

Are statins making my hair fall out? DR MARTIN SCURR answers
DR MARTIN SCURR: If hair growth is restored - and it takes two or three months to be certain - then the next stage is a re-challenge, where you try the original medication again. (Source: the Mail online | Health)
Source: the Mail online | Health - June 23, 2020 Category: Consumer Health News Source Type: news

Statins Tied to Significantly Lower Death Rate From Ovarian Cancer
(Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - June 22, 2020 Category: Cancer & Oncology Tags: Cardiology, Gynecology, Oncology, News, Source Type: news

Statins Tied to Significantly Lower Death Rate From Ovarian Cancer
MONDAY, June 22, 2020 -- Statin drugs, used for decades to treat high cholesterol, may also reduce deaths for women with ovarian cancer, a new study suggests. " These drugs are appealing as they are widely used, inexpensive, and well-tolerated in... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - June 22, 2020 Category: General Medicine Source Type: news

Cardioprotective Therapy Use Lower With Cancer History
THURSDAY, June 18, 2020 -- Cardioprotective therapies, especially statins and antiplatelets, are underutilized in patients with a history of cancer (CaHx), according to a research letter published in the June 1 issue of JACC: CardioOncology. Rossana... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 18, 2020 Category: Pharmaceuticals Source Type: news

Cardioprotective Meds Underutilized in Patients With Cancer History Cardioprotective Meds Underutilized in Patients With Cancer History
Statin and antiplatelet use was especially suboptimal, despite patients having comparable CVD and risk factors to those without previous cancer.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 16, 2020 Category: Cancer & Oncology Tags: Cardiology News Source Type: news

Cancer patients less likely to be prescribed cardioprotective medications
(American College of Cardiology) As cancer survivor rates increase with modern treatments, cardiovascular disease (CVD) rates are rising in cancer patients and survivors and CVD has emerged as a leading cause of long-term preventable death in this population. Even though cardioprotective medications--including statins, ACE inhibitors and antiplatelet therapies--are frontline primary and secondary CVD prevention, patients with a prior or current history of cancer had lower rates of utilization compared to those without cancer, according to a research letter published in JACC: CardioOncology. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 16, 2020 Category: Cancer & Oncology Source Type: news

Could Statins Reduce the Severity of COVID-19?
The cholesterol-lowering drugs quell inflammation and reverse endothelial tissue damage, hints that they might curb the body ’s excessive immune response to SARS-CoV-2 infection. (Source: The Scientist)
Source: The Scientist - June 12, 2020 Category: Science Tags: News & Opinion Source Type: news

Women are 10 percent less likely than men to be given cholesterol-lowering statin drugs
Overall, researchers found that doctors treating women prescribe cardiovascular disease medications less often than do doctors treating men. (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - June 8, 2020 Category: Consumer Health News Authors: Linda Searing Source Type: news

Deep learning refines cardiac CT results
A deep-learning algorithm refines cardiac CT results by automatically eliminating...Read more on AuntMinnie.comRelated Reading: CT CAC directs statin therapy in African Americans CT CAC predicts risk of death in smokers AI spots heart disease on CT lung screening exams CT CAC linked to cardiovascular mortality in young adults Elevated CT CAC scores linked to future heart failure (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - June 5, 2020 Category: Radiology Source Type: news

Drug pricing regulator fixes prices of 40 formulation drugs
The regulator has reduced the maximum retail price of a new class of drugs, including statins, diabetes drugs, cardiovascular and combination drugs. The revised prices will have an impact on the manufacturers of these formulations, including Sun Pharma and Zydus Healthcare. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - June 4, 2020 Category: Pharmaceuticals Source Type: news

Healthy People Shouldn ’ t Take Daily Aspirin To Prevent Heart Disease, Review Finds
(CNN) — Still taking a daily aspirin to ward off heart attacks? You might want to think again, according to a new review. Aspirin is still one of the most commonly used medications in the world, even though it’s no longer recommended as a preventative by many health authorities. There is no evidence that low-dose aspirin — less than 325 milligrams a day — should be taken by most adults in good cardiovascular health, according to a new review of existing research that published Wednesday in the British Journal of Clinical Pharmacology. The review, which focused on the risks and benefits of low-dose d...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - June 3, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News aspirin CNN Source Type: news

Statin Use in Nursing Home Residents With Life-Limiting Illness Statin Use in Nursing Home Residents With Life-Limiting Illness
How prevalent is statin use among terminally ill nursing home residents? Should statins be discontinued in those unlikely to benefit from continued use?Journal of the American Geriatrics Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 25, 2020 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news