Could this one-time ‘epigenetic’ treatment control cholesterol?
In this episode:00:49 What caused the Universe to become fully transparent?Around 13 billion years ago, the Universe was filled with a dense ‘fog’ of neutral hydrogen that blocked certain wavelengths of light. This fog was lifted when the hydrogen was hit by radiation in a process known as reionisation, but the source of this radiation has been debated. Now, researchers have used the JWST to peer deep into the Universe’s past and found that charged particles pouring out from dwarf galaxies appear to be the the main driver for reionization. This finding could help researchers understand how some of the structures we n...
Source: Nature Podcast - February 28, 2024 Category: Science Authors: Springer Nature Limited Source Type: podcasts

JAMA Cardiology : Effects of Pitavastatin on Coronary Artery Disease and Inflammatory Biomarkers in HIV
Interview with Michael T. Lu, MD, MPH, author of Effects of Pitavastatin on Coronary Artery Disease and Inflammatory Biomarkers in HIV: Mechanistic Substudy of the REPRIEVE Randomized Clinical Trial, and Matthew J. Feinstein, MD, MSc, author of Statins, Inflammation, and Tissue Context in REPRIEVE. Hosted by Robert Bonow, MD. Related Content: Effects of Pitavastatin on Coronary Artery Disease and Inflammatory Biomarkers in HIV Statins, Inflammation, and Tissue Context in REPRIEVE (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - February 21, 2024 Category: General Medicine Authors: The JAMA Network Source Type: podcasts

Atorvastatin to Reduce Risk of Anthracycline-Associated Cardiac Dysfunction
Anthracyclines are used to treat a variety of cancers, but treatment may be limited by cardiac toxicity. JAMA Executive Editor Gregory Curfman, MD, discusses a new clinical trial on the use of atorvastatin to prevent anthracycline-induced cardiac toxicity with authors Tomas Neilan, MD, MPH, and Marielle Scherrer-Crosbie, MD, PhD. Related Content: Atorvastatin for Anthracycline-Associated Cardiac Dysfunction (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - August 8, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts

Bempedoic Acid in Statin-Intolerant Patients
Bempedoic acid is an effective option for some statin-intolerant patients with an elevated predicted risk of cardiovascular events. However, as JAMA Executive Editor Gregory Curfman, MD, discusses with editorialist Dhruv S. Kazi, MD, MSc, MS, bempedoic acid should not be considered a substitute for statins, which remain the first-line therapy for primary prevention. Related Content: Bempedoic Acid for Primary Prevention of Cardiovascular Events in Statin-Intolerant Patients Bempedoic Acid for High-Risk Primary Prevention of Cardiovascular Disease (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - July 11, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts

Diabetes Core Update – June 2023
Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 25 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update d     iscusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a...
Source: Diabetes Core Update - June 8, 2023 Category: Endocrinology Authors: American Diabetes Association Source Type: podcasts

Statin Treatment Strategies for Patients With Coronary Artery Disease, Heterogeneous Treatment Effects of Therapeutic-Dose Heparin in Patients Hospitalized for COVID-19, Review of Diagnosis and Treatment of Acute Myocarditis, and more
Editor’s Summary by Linda Brubaker, MD, MS, Senior Editor of JAMA, the Journal of the American Medical Association, for the April 4, 2023, issue. Related Content: Audio Highlights (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - April 4, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts

JAMA Cardiology : Effect of Nudges to Clinicians, Patients, or Both to Increase Statin Prescribing
Interview with Mitesh S. Patel, MD, MBA, author of Effect of Nudges to Clinicians, Patients, or Both to Increase Statin Prescribing: A Cluster Randomized Clinical Trial, and Faraz S. Ahmad, MD, MS, author of Nudging to Improve Cardiovascular Care—Clinicians, Patients, or Both. Hosted by Sadiya Sana Khan, MD, MS. Related Content: Effect of Nudges to Clinicians, Patients, or Both to Increase Statin Prescribing Nudging to Improve Cardiovascular Care—Clinicians, Patients, or Both (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - November 30, 2022 Category: General Medicine Authors: The JAMA Network Source Type: podcasts

JAMA Neurology : Evaluation of Simvastatin as a Disease-Modifying Treatment for Patients With Parkinson Disease
Interview with Camille Carroll, MD, PhD, author of Evaluation of Simvastatin as a Disease-Modifying Treatment for Patients With Parkinson Disease: A Randomized Clinical Trial. Hosted by Cynthia E. Armand, MD. Related Content: Evaluation of Simvastatin as a Disease-Modifying Treatment for Patients With Parkinson Disease (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - November 1, 2022 Category: General Medicine Authors: The JAMA Network Source Type: podcasts

USPSTF Recommendation: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults
Interview with John B. Wong, MD, USPSTF member and coauthor of Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS. Related Content: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults Statin Use for the Primary Prevention of Cardiovascular Disease in Adults Statins for the Prevention of Cardiovascular Disease Statin Usage in Primary Prevention—Comparing the USPSTF Recommendations With the AHA/ACC/Multisociety Guidelines Statins for Primary Cardiovas...
Source: JAMA Author Interviews - August 23, 2022 Category: General Medicine Authors: JAMA Network Source Type: podcasts

Radiotherapy With vs Without Chemotherapy for Nasopharyngeal Carcinoma, Trends in Lipids Concentrations in US Adults, USPSTF Recommendation Statement on Statin Use, and more
Editor's Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief of JAMA, the Journal of the American Medical Association, for the August 23/30, 2022 issue.   (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - August 23, 2022 Category: General Medicine Authors: JAMA Network Source Type: podcasts

TWiV 922: TWiV clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses monkeypox infection in humans across 16 countries, pregnancy outcomes after SARS-CoV-2 infection by trimester, vaccination intent and belief, antiviral drug treatment for non-severe disease, the association of smoking with infected hospitalized patients, the association of Paxlovid on negative conversion rates among high-risk patients with COVID-19, safety and efficacy of Molnupiravir, usage of enoxaparin for primary thromboprophylaxis, statin and aspirin as therapy in infected patients, post-COVID-19 conditions among children 90 days after SARS-CoV-2 Infection, and sympt...
Source: This Week in Virology - MP3 Edition - July 30, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Diabetes Core Update – February 2022
Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 20 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatmen...
Source: Diabetes Core Update - January 29, 2022 Category: Endocrinology Authors: American Diabetes Association Source Type: podcasts

TWiV 823: COVID-19 clinical update #86 with Dr. Daniel Griffin
In COVID-19 clinical update #86, Dr. Griffin discusses virologic features of infection in children, antibody tests should not be used to asses level of protection, test-to-stay programs in schools, FDA authorizes Moderna boosters, results of TOGETHER trial for fluvoxamine, statins and 28 day mortality, and cognitive function in patients. Hosts: Daniel Griffin and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode 115,000 healthcare worker deaths (Stat News) Virology features of infection in children (J Inf Dis) Antibody tests not for assessing pr...
Source: This Week in Virology - MP3 Edition - October 30, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

FDA requests removal of strongest warning against using cholesterol-lowering statins during pregnancy; still advises most pregnant patients should stop taking statins
Listen to an audio podcast of the July 20, 2021 FDA Drug Safety Communication, FDA requests removal of strongest warning against using cholesterol-lowering statins during pregnancy; still advises most pregnant patients should stop taking statins (Source: FDA Drug Safety Podcasts)
Source: FDA Drug Safety Podcasts - July 22, 2021 Category: Drugs & Pharmacology Authors: U.S. Food and Drug Administration, Center for Drug Evaluation and Research Source Type: podcasts