NIDCR's Winter 2020 E-Newsletter
Having trouble viewing this email? View it as a Web page. NIDCR's Winter 2020 E-Newsletter In this issue: NIDCR News Funding Opportunities NIH/HHS News Funding Notices Science Advances Subscribe to NICDR News Grantee News   NIDCR News NIDCR Welcomes New Director Rena D’Souza Rena N. D’Souza, DDS, MS, PhD, was sworn in as the director of NIDCR by NIH Director Francis S. Collins, MD, PhD, on October 13. Prior to joining NIH, Dr. D’Souza was the assistant vice president for academic affairs and education for health s...
Source: NIDCR Science News - December 4, 2020 Category: Dentistry Source Type: news

Radiofrequency Ablation Blocks Hip, Shoulder Arthritis Pain Radiofrequency Ablation Blocks Hip, Shoulder Arthritis Pain
A new treatment'stuns'sensory nerves and reduces pain signals in knee and shoulder osteoarthritis.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 4, 2020 Category: Consumer Health News Tags: Radiology News Source Type: news

FDA approves Xolair ® (omalizumab) for adults with nasal polyps
             Basel, 01 December 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the U.S. Food and Drug Administration (FDA) has approved the company ’s supplemental Biologics License Application (sBLA) for Xolair® (omalizumab) for the add-on maintenance treatment of nasal polyps in adult patients 18 years of age and older with inadequate response to nasal corticosteroids.1 Nasal polyps can lead to a loss of smell and nasal congestion, and frequently co-occur with other respiratory conditions, such as allergies and asthma. With this ap...
Source: Roche Media News - December 1, 2020 Category: Pharmaceuticals Source Type: news

FDA approves Xolair ® (omalizumab) for adults with nasal polyps
             Basel, 01 December 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the U.S. Food and Drug Administration (FDA) has approved the company ’s supplemental Biologics License Application (sBLA) for Xolair® (omalizumab) for the add-on maintenance treatment of nasal polyps in adult patients 18 years of age and older with inadequate response to nasal corticosteroids.1 Nasal polyps can lead to a loss of smell and nasal congestion, and frequently co-occur with other respiratory conditions, such as allergies and asthma. With this ap...
Source: Roche Investor Update - December 1, 2020 Category: Pharmaceuticals Source Type: news

ACR Convergence: Psoriatic Arthritis ACR Convergence: Psoriatic Arthritis
Dr Saakshi Khattri reviews key abstracts about psoriatic arthritis from the annual ACR meeting, including a tool for early detection and a study showing dactylitis may signal an aggressive phenotype.Medscape (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 1, 2020 Category: Consumer Health News Tags: None ReCAP Source Type: news

COVID-19 Vaccines Coming Soon – When Can I Get One?
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Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - December 1, 2020 Category: Consumer Health News Authors: CBS Boston Tags: Boston News Covid-19 Boston, MA Healthcare Status Coronavirus Coronavirus Vaccine Moderna Moderna Therapeutics Source Type: news

Rheumatoid arthritis: Thunder god vine is comparable to drug treatments, research suggests
RHEUMATOID arthritis can be excruciating but you do not have to accept it as your lot. Thunder god vine supplementation has been proven to rival a standard rheumatoid arthritis drug in its ability to alleviate symptoms. (Source: Daily Express - Health)
Source: Daily Express - Health - November 30, 2020 Category: Consumer Health News Source Type: news

Relationships of the stand-up time to falls and fractures in patients with rheumatoid arthritis: results from the CHIKARA study - Tada M, Yamada Y, Mandai K, Hidaka N.
AIM: Patients with rheumatoid arthritis (RA) have a higher risk of falls and fractures due to muscle weakness and painful joints of the lower extremities. Evaluation of muscle functions is important to predict falls and fractures. The aim was to investigat... (Source: SafetyLit)
Source: SafetyLit - November 30, 2020 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

Longitudinal research on the bidirectional association between depression and arthritis - Ke C, Qiao Y, Liu S, Rui Y, Wu Y.
PURPOSE: Studies evaluating the mutual relation between depression and arthritis have been limited and yielded inconsistent results. The aim of this study was to investigate the bidirectional relationship between depression and arthritis in a middle-aged a... (Source: SafetyLit)
Source: SafetyLit - November 28, 2020 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Use of PROMIS ® to screen for depression in children with arthritis - Yan Y, Rychlik KL, Rosenman MB, Miller ML.
BACKGROUND: Children with JIA may experience difficulty with health related quality of life (HRQOL). The Patient Reported Outcomes Measurement Information System (PROMIS) a patient related outcome (PRO) measure, covers HRQOL domains that include physical f... (Source: SafetyLit)
Source: SafetyLit - November 27, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Arthritis symptoms: Hard and knobbly fingers are linked to osteoarthritis
ARTHRITIS can affect any joint in the body. However, take a look at your hand. Are your fingertips hard or knobbly? This could be a sign of osteoarthritis. (Source: Daily Express - Health)
Source: Daily Express - Health - November 25, 2020 Category: Consumer Health News Source Type: news

New breakthrough in the treatment of rheumatoid arthritis
(University of Oxford) People with Rheumatoid Arthritis (RA) could soon benefit from a new drug treatment, otilimab, that not only suppresses inflammation but also significantly reduces patient reported pain scores. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 25, 2020 Category: International Medicine & Public Health Source Type: news

Roche's Actemra Helps the Sickest COVID-19 Patients, Study Shows Roche's Actemra Helps the Sickest COVID-19 Patients, Study Shows
Roche's Actemra helped the sickest COVID-19 patients in a 303-patient study, the trial's lead investigator said on Thursday, bolstering what has been mixed evidence that the arthritis drug can be repurposed to help in the pandemic.Reuters Health Information (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - November 23, 2020 Category: Intensive Care Tags: Infectious Diseases News Source Type: news

After Methotrexate Failure, Is JAK Inhibitor or Biologic Next? After Methotrexate Failure, Is JAK Inhibitor or Biologic Next?
What is the next step in treatment after a person with rheumatoid arthritis fails to adequately respond to methotrexate -- a Janus kinase inhibitor or a biologic?Medscape Medical News (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - November 23, 2020 Category: Drugs & Pharmacology Tags: Rheumatology News Source Type: news

Increased falls risk in people with psoriatic arthritis-related foot problems: a novel finding - Carter K, Walmsley S, Oliffe M, Hassett G, Turner ADE.
[Abstract unavailable] Language: en... (Source: SafetyLit)
Source: SafetyLit - November 23, 2020 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Innovent Announces NMPA Granted New Indication Approval for SULINNO(R) (Adalimumab Injection) in China for the Treatment of Polyarticular Juvenile Idiopathic Arthritis
SAN FRANCISCO and SUZHOU, China, Nov. 23, 2020 -- (Healthcare Sales & Marketing Network) -- Innovent Biologics, Inc. (Innovent) (HKEX: 01801), a world-class biopharmaceutical company that develops, manufactures and commercializes high quality medicines fo... Biopharmaceuticals, Regulatory Innovent Biologics, SULINNO , adalimumab (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - November 23, 2020 Category: Pharmaceuticals Source Type: news

FDA Authorizes Arthritis Drug Combo for COVID-19
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - November 23, 2020 Category: General Medicine Source Type: news

Arthritis Drug Combo for COVID-19 Authorized by FDA
Title: Arthritis Drug Combo for COVID-19 Authorized by FDACategory: Health NewsCreated: 11/21/2020 12:00:00 AMLast Editorial Review: 11/23/2020 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - November 23, 2020 Category: Rheumatology Source Type: news

Strides Pharma Science gets USFDA nod for Prednisone tablets
Strides Pharma Science Ltd on Monday said it has received approval from the US health regulator for its generic version of Prednisone tablets, prescribed for a variety of conditions, including allergies, respiratory illness and arthritis. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - November 23, 2020 Category: Pharmaceuticals Source Type: news

DR ELLIE CANNON: Don't rely on cider vinegar to cure your lumps... or anything
DR ELLIE CANNON: Cider vinegar is recommended for everything from arthritis pain to weight loss. There's been a fair bit of research into it over the years, and none of these claims stands up. (Source: the Mail online | Health)
Source: the Mail online | Health - November 21, 2020 Category: Consumer Health News Source Type: news

FDA Authorizes Arthritis Drug Combo for COVID-19
The combination is meant for patients who need supplemental oxygen or mechanical ventilation. (Source: WebMD Health)
Source: WebMD Health - November 21, 2020 Category: Consumer Health News Source Type: news

Arthritis drug and remdesivir combo get emergency FDA approval
Baricitinib combined with remdesivir improved survival odds by a third for hospitalized patients on oxygen, compared to remdesivir alone - but now WHO officials say the antiviral does not work. (Source: the Mail online | Health)
Source: the Mail online | Health - November 20, 2020 Category: Consumer Health News Source Type: news

A'Stunning' Alternative Rx for Arthritic Joints?
Title: A'Stunning'Alternative Rx for Arthritic Joints?Category: Health NewsCreated: 11/19/2020 12:00:00 AMLast Editorial Review: 11/20/2020 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - November 20, 2020 Category: Rheumatology Source Type: news

BU rheumatologist receives Arthritis Foundation award
(Boston University School of Medicine) David T. Felson, MD, PhD, professor of medicine and epidemiology at Boston University's Schools of Medicine and Public Health (BUSM, BUSPH), has been honored with the Lee C. Howley, Sr. Prize for Arthritis Science Service from the Arthritis Foundation. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 20, 2020 Category: International Medicine & Public Health Source Type: news

FDA Gives Emergency Approval To Covid-19 Treatment That Combines Eli Lilly Arthritis Drug With Remdesivir
This is the first drug combination given emergency approval by the FDA for the coronavirus. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - November 20, 2020 Category: Pharmaceuticals Authors: Rachel Sandler, Forbes Staff Tags: Business /business Innovation /innovation Healthcare /healthcare Breaking breaking-news Coronavirus Source Type: news

Tocilizumab: Arthritis drug may treat severe Covid
Early signs suggest it may help patients with severe breathing difficulties who are on ventilators. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - November 19, 2020 Category: Consumer Health News Source Type: news

Arthritis drug offers hope for severely ill Covid patients
Scientists optimistic it can be added to armoury of treatments for most critically sick (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - November 19, 2020 Category: Pharmaceuticals Source Type: news

A'Stunning' Alternative Rx for Arthritic Joints?
THURSDAY, Nov. 19, 2020 -- A procedure that " stuns " pain-sensing nerves might offer relief to people with severe arthritis of the hip or shoulder, a small, preliminary study suggests. The procedure is a form of radiofrequency ablation, where... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 19, 2020 Category: General Medicine Source Type: news

Arthritis drug tocilizumab can help critically-ill Covid patients recover, trial finds
Patients given the drug in the REMAP-CAP trial, led by Imperial College London, were 87 per cent more likely to see their illness improve than those not given the drug. (Source: the Mail online | Health)
Source: the Mail online | Health - November 19, 2020 Category: Consumer Health News Source Type: news

Periodontal Pathogens Linked to Atherosclerosis in RA
WEDNESDAY, Nov. 18, 2020 -- For patients with rheumatoid arthritis (RA), immunoreactivity against Aggregatibacter actinomycetemcomitans serotype b (anti-Aa) and Aa leukotoxin A (anti-LtxA) is associated with atherosclerosis, according to a study... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 18, 2020 Category: Pharmaceuticals Source Type: news

Does an Autoimmune Disorder Affect My Covid-19 Risks?
Patients with conditions like lupus and rheumatoid arthritis, who may take immune suppressing drugs, do not appear to be at greatly increased risk from coronavirus. (Source: NYT Health)
Source: NYT Health - November 18, 2020 Category: Consumer Health News Authors: Mikkael A. Sekeres, M.D. Tags: Coronavirus (2019-nCoV) Autoimmune Diseases Immune System Rheumatoid Arthritis Lupus Erythematosus Hygiene and Cleanliness Content Type: Service Source Type: news

Arthritis: Four effective remedies to reduce joint pain and inflammation
ARTHRITIS can dampen your mood. Are you experiencing pain and stiffness? If so, here are four effective remedies to reduce inflammation and swelling. (Source: Daily Express - Health)
Source: Daily Express - Health - November 18, 2020 Category: Consumer Health News Source Type: news

Overweight With Arthritic Knees? You Might Want to Avoid Tennis
Title: Overweight With Arthritic Knees? You Might Want to Avoid TennisCategory: Health NewsCreated: 11/17/2020 12:00:00 AMLast Editorial Review: 11/18/2020 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - November 18, 2020 Category: Rheumatology Source Type: news

Link between periodontitis and cardiovascular disease in individuals with rheumatoid arthritis
(Wiley) Rates of both periodontal disease and cardiovascular disease are elevated in individuals with rheumatoid arthritis. New research published in Arthritis& Rheumatology suggests that immune responses to certain bacteria that cause periodontal disease may play a role in patients' higher cardiovascular disease risk. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 18, 2020 Category: International Medicine & Public Health Source Type: news

Outpatient radiology procedure offers arthritis relief
A new outpatient radiology procedure relieves pain in patients with hip or...Read more on AuntMinnie.comRelated Reading: FDA approves RFID option for Definity contrast RF-induced heating poses MRI risk in patients with tattoos Medicare requires prior authorization for venous ablation 3D image analysis spots cartilage changes on knee MRI New 3D CT technique tops x-ray for diagnosing arthritis (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - November 18, 2020 Category: Radiology Source Type: news

Overweight With Arthritic Knees? You Might Want to Avoid Tennis
TUESDAY, Nov. 17, 2020 -- Stay off the court: For overweight people with arthritic knees, racket sports like tennis and racquetball may accelerate degeneration of the joints, a new study finds. Exercise can benefit overweight people, but the wrong... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 17, 2020 Category: General Medicine Source Type: news

PCORI board approves $34 million in funding for maternal mental health, arthritis
(Patient-Centered Outcomes Research Institute) The Patient-Centered Outcomes Research Institute (PCORI) Board of Governors today approved $34 million to fund seven comparative clinical effectiveness research (CER) studies designed to improve care for health conditions that impose high burdens on patients, their families and the health care system. They also acknowledged its newest seven board members, appointed by the US Government Accountability Office in late September, at their first public meeting. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 17, 2020 Category: Cancer & Oncology Source Type: news

Red eyes could be the first sign of arthritis in your SPINE
Student Dasha Karzunina assumed at first that the red, painful eye she had developed while revising for her university exams was a simple infection. (Source: the Mail online | Health)
Source: the Mail online | Health - November 16, 2020 Category: Consumer Health News Source Type: news

New procedure shows promise for pain relief in shoulder, hip arthritis
An outpatient procedure called cooled radio-frequency ablation reduces pain by more than 80% in people with moderate to severe arthritis in their hip and shoulder joints, a study says. (Source: Health News - UPI.com)
Source: Health News - UPI.com - November 16, 2020 Category: Consumer Health News Source Type: news

ACR Previews New Pharmacotherapy Guidelines for RA
MONDAY, Nov. 16, 2020 -- The American College of Rheumatology (ACR) previewed its 2020 Guideline for the Management of Rheumatoid Arthritis (RA) at ACR Convergence, the College's annual meeting, held virtually from Nov. 5 to 9. Panelists, including... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 16, 2020 Category: Pharmaceuticals Source Type: news

Arthritis treatment: Devil’s claw may rival 'conventional medicines' - what is it?
ARTHRITIS can be insufferable if you have a particularly severe case of it but there are ways to alleviate it. Supplementing with devil's claw may be as effective as conventional medicines - what is it? (Source: Daily Express - Health)
Source: Daily Express - Health - November 16, 2020 Category: Consumer Health News Source Type: news

Reflex Sympathetic Dystrophy (RSD, Complex Regional Pain Syndrome Type 1, CRPS)
Title: Reflex Sympathetic Dystrophy (RSD, Complex Regional Pain Syndrome Type 1, CRPS)Category: Diseases and ConditionsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 11/16/2020 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - November 16, 2020 Category: Rheumatology Source Type: news

Novel technique 'stuns' arthritis pain in shoulder and hip
(Radiological Society of North America) A novel outpatient procedure offers lasting pain relief for patients suffering from moderate to severe arthritis in their hip and shoulder joints, according to a study presented at the annual meeting of the Radiological Society of North America (RSNA). Researchers said the procedure could help reduce reliance on addictive opiates. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 16, 2020 Category: International Medicine & Public Health Source Type: news

Arthritis drug may improve COVID-19 survival among elderly patients, says study
In the research, published in the journal Science Advances, 83 patients with a median age of 81 and all suffering from moderate to severe COVID-19 infection were given a drug called baricitinib. (Source: The Economic Times)
Source: The Economic Times - November 16, 2020 Category: Consumer Health News Source Type: news

New arthritis pill that can end the hell of stiff joints
A new medicine called Rinvog could see symptoms disappear in 40 per cent of the 400,000 patients in Britain who are affected by rheumatoid arthritis. (Source: the Mail online | Health)
Source: the Mail online | Health - November 14, 2020 Category: Consumer Health News Source Type: news

Methotrexate and HCQ Split on Cardiovascular Outcomes in RA Methotrexate and HCQ Split on Cardiovascular Outcomes in RA
No significant differences in major adverse cardiovascular events emerged between methotrexate and hydroxychloroquine treatment in a comparison of adults 65 years or older with rheumatoid arthritis.Medscape Medical News (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - November 13, 2020 Category: Drugs & Pharmacology Tags: Rheumatology News Source Type: news

Arthritis: Three key health indicators which slow down the progression of osteoarthritis
ARTHRITIS symptoms include swelling, pain, stiffness and decreased range of motion. Over time, the condition can worsen, leading to more severe flare-ups. Work on three key areas to slow down the progression of the disease. (Source: Daily Express - Health)
Source: Daily Express - Health - November 13, 2020 Category: Consumer Health News Source Type: news

JIA Guideline Calls for Earlier Use of Targeted Therapies JIA Guideline Calls for Earlier Use of Targeted Therapies
A draft guideline for the management of patients with juvenile idiopathic arthritis reflects changes in therapy away from reliance on NSAIDs and glucocorticoids.Medscape Medical News (Source: Medscape Pediatrics Headlines)
Source: Medscape Pediatrics Headlines - November 13, 2020 Category: Pediatrics Tags: Rheumatology News Source Type: news

COVID-19 survival among elderly patients could be improved by arthritis drug
(Imperial College London) A type of arthritis drug may reduce the risk of dying for elderly patients with COVID-19. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 13, 2020 Category: Infectious Diseases Source Type: news

Baricitinib treatment linked to reduced mortality in COVID-19 patients
(Karolinska Institutet) The rheumatoid arthritis drug baricitinib can block viral entry and reduce mortality in patients with moderate to severe COVID-19, according to translational research by an international team coordinated by researchers from Karolinska Institutet in Sweden. The findings, published in the journal Science Advances, support the continuation of ongoing randomized clinical trials. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 13, 2020 Category: International Medicine & Public Health Source Type: news