STELARA ® (ustekinumab) Demonstrated Sustained Symptomatic and Corticosteroid-Free Remission Through Four Years in Adults with Moderately to Severely Active Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, October 10, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced final data from the long-term extension (LTE) of the Phase 3 UNIFI study demonstrating efficacy and safety of STELARA® (ustekinumab) through four years of treatment in adult patients with moderately to severely active ulcerative colitis (UC).1 Among all patients who had achieved clinical responsea with STELARA during induction, 64.9 percent were in symptomatic remissionb after 44 weeks of maintenance. At week 200 (four years), this proportion of patients was 55.2 percent; the majority (96.4 percen...
Source: Johnson and Johnson - October 10, 2022 Category: Pharmaceuticals Source Type: news
Results of Novel Clinical Study of Guselkumab and Golimumab Combination Therapy Show Adults with Moderately to Severely Active Ulcerative Colitis Maintained Higher Rates of Clinical, Histologic, and Endoscopic Remission at Week 38
SPRING HOUSE, PENNSYLVANIA, October 10, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from an ongoing analysis of a Phase 2a clinical trial showing adults with moderately to severely active ulcerative colitis (UC) who received 12 weeks of combination induction therapy with guselkumab and golimumab, followed by a transition to guselkumab alone for maintenance, achieved a clinical remission ratea (based on the modified Mayo score [mMayo])b at week 38 of 47.9 percent, a higher rate than induction and maintenance treatment with either guselkumab alone (31.0 percent) or golimumab al...
Source: Johnson and Johnson - October 10, 2022 Category: Pharmaceuticals Source Type: news
Drug Shows Promise Against Autoimmune Disease Scleroderma
MONDAY, Oct. 10, 2022 -- Researchers report early success with using an existing rheumatoid arthritis (RA) drug to treat systemic sclerosis, a rare but potentially devastating autoimmune condition.
The disease, a subset of scleroderma, hardens the... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - October 10, 2022 Category: General Medicine Source Type: news
Tofacitinib Shows Promise Against Autoimmune Disease Scleroderma
MONDAY, Oct. 10, 2022 -- Researchers report early success with using an existing rheumatoid arthritis (RA) drug to treat systemic sclerosis, a rare but potentially devastating autoimmune condition.
The disease, a subset of scleroderma, hardens the... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - October 10, 2022 Category: General Medicine Source Type: news
Arthritis: Nine foods to reduce your risk of joint problems - high in vitamin C
Eating foods packed full of vitamin C could help lower your risk of arthritis and joint problems. (Source: Daily Express - Health)
Source: Daily Express - Health - October 9, 2022 Category: Consumer Health News Source Type: news
No Special Heart Risk With JAK Inhibitors, Study Finds
(MedPage Today) -- Patients taking Janus kinase (JAK) inhibitors for rheumatoid arthritis experienced similar cardiovascular outcomes as those using the tumor necrosis factor (TNF) blocker adalimumab (Humira), analysis of French national registry... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - October 7, 2022 Category: Cardiology Source Type: news
Unusual bitter melon supplement shown to improve arthritis in study - lowers inflammation
The nutrient can cut down your need to use painkillers in three months, research suggests. (Source: Daily Express - Health)
Source: Daily Express - Health - October 7, 2022 Category: Consumer Health News Source Type: news
High Costs Seen for Nonoperative Therapy for Late-Stage Knee Arthritis Prior to TKA
WEDNESDAY, Oct. 5, 2022 -- Patients with late-stage knee osteoarthritis (OA) incur significant costs for nonoperative treatments in the year before total knee arthroplasty (TKA), and the type and cost of these treatments vary considerably, according... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 5, 2022 Category: Pharmaceuticals Source Type: news
14-year-old girl denied arthritis medication amid Arizona abortion ban
#girl #arizona (Source: Reuters: Health)
Source: Reuters: Health - October 5, 2022 Category: Consumer Health News Source Type: news
Pirfenidone Promising for RA-Linked Interstitial Lung Disease
TUESDAY, Oct. 4, 2022 -- Pirfenidone may slow the rate of decline of forced vital capacity (FVC) among patients with rheumatoid arthritis-associated interstitial lung disease (RA-ILD), according to a study published online Sept. 5 in The Lancet... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 4, 2022 Category: Pharmaceuticals Source Type: news
Clinical Predictors of Methotrexate Response in RA Patients Clinical Predictors of Methotrexate Response in RA Patients
Could certain factors determine treatment response to methotrexate in rheumatoid arthritis patients? A new study uses a machine learning approach to identify potential predictors.Arthritis Research & Therapy (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 4, 2022 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news
Arthritis: 'Distilled' alcohol increases the risk of 'painful' crystals forming in joints
The popular type of beverage should be avoided during an inflammatory attack, warns health body Mayo Clinic. (Source: Daily Express - Health)
Source: Daily Express - Health - October 1, 2022 Category: Consumer Health News Source Type: news
Sex Differences Seen in Inflammatory Arthritis Healthcare Use Sex Differences Seen in Inflammatory Arthritis Healthcare Use
Women ’s higher risk of conditions such as osteoarthritis and pain and fatigue may help to explain why overall healthcare resource use was higher in female patients with inflammatory arthritis.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 30, 2022 Category: Consumer Health News Tags: Rheumatology News Source Type: news
Arthritis: 8 types of fish can cause acid crystals to build up in joints - 'very painful'
The effect is attributed to purine compounds found in the fish, which raise uric acid levels. (Source: Daily Express - Health)
Source: Daily Express - Health - September 30, 2022 Category: Consumer Health News Source Type: news
Severe COVID-19 –Related Outcomes Found Worse in Men With RA Severe COVID-19 –Related Outcomes Found Worse in Men With RA
A retrospective electronic health record study of patients with rheumatoid arthritis and COVID-19 showed that men had more baseline comorbidities and increased risk of COVID-19 outcomes than females.Medscape Medical News (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - September 29, 2022 Category: Infectious Diseases Tags: Rheumatology News Source Type: news
