Autoimmune disease flares: stress, grief, and management tips
Autoimmune diseases occur when the immune system mistakenly attacks healthy cells and tissues in the body. More than 80 recognized autoimmune diseases exist, including alopecia areata, rheumatoid arthritis, psoriasis, lupus, multiple sclerosis, celiac disease, scleroderma, and Raynaud’s. These conditions can cause a wide range of symptoms, making management crucial for maintaining a good quality of
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Autoimmune disease flares: stress, grief, and management tips originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - April 4, 2024 Category: General Medicine Authors: Nancie Wiseman Attwater Tags: Conditions Rheumatology Source Type: blogs
Efferocytosis in the Context of Aging and Age-Related Disease
There is something of a tradition in the aging research community of writing reviews that attempt to summarize everything that is known of a single specific cellular behavior in the context of the panoply of cell and tissue dysfunction observed in aging. Today it is the turn of efferocytosis, the clearance of dying cells and their immediate debris by phagocytes such as macrophages of the innate immune system. It is fairly straightforward to mount an argument to suggest that more efficient efferocytosis is a good thing, as unwanted consequences attend the presence of lingering cell corpses cluttering up tissue. Like autopha...
Source: Fight Aging! - April 1, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Test results!
Hi everyone! Oh dear, I’ve been gone for quite some time, haven’t I? Life really does get in the way of plans sometimes.
In this period, in addition to being super busy with a million other things, I’ve been focusing on getting my arthritic knee in shape. There’s no going back to the knee I had in my 20s, of course, but I can try at least to stop it from getting worse, mainly with physiotherapy. Okay, but enough about my knee….that’s not the reason I’ve written this post…
Today I have some good news that I’d like to share with you…
Here’s the news: I just...
Source: Margaret's Corner - February 21, 2024 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll boswellia curcumin osteoarthritis Source Type: blogs
The Impact of US Abortion Policy on Rheumatology Clinical Practice: a Cross-Sectional Survey of Rheumatologists
Bonnie L. Bermas (University of Texas Southwestern), Irene Blanco (Northwestern University), Rosalind Ramsey-Goldman (Northwestern University), Ashira D. Blazer (Cornell University), et al., The Impact of US Abortion Policy on Rheumatology Clinical Practice: a Cross-Sectional Survey of Rheumatologists, Arthritis& Rheumatology... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - January 14, 2024 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs
Fight Aging! Newsletter, January 8th 2024
This study examined whether the local injection of the supernatant of activated PRP (saPRP) into the salivary gland (SG) could help prevent aging-induced SG dysfunction and explored the mechanisms responsible for the protective effects on the SG hypofunction.
Human salivary gland epithelial cells (hSGEC) were treated with saPRP or PRP after senescence through irradiation. The significant proliferation of hSGEC was observed in saPRP treated group compared to irradiation only group and irradiation + PRP group. Cellular senescence, apoptosis, and inflammation were significantly reduced in the saPRP group.
Th...
Source: Fight Aging! - January 7, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Should We Think of Rheumatoid Arthritis as an Age-Related Condition?
There are medical conditions that occur only in old age, and there are medical conditions, such as cancer, that can occur at any point in life, but more so in the old. Then there are grey area conditions that may occur to some greater degree in later life, or be worse in later life, but this is by no means widely appreciated. Where does the autoimmune condition of rheumatoid arthritis sit in this spectrum? Unlike cancer, it is not commonly thought of as an age-related disease, even though it is certainly affected and made worse by the processes of aging. This point is discussed in today's open access commentary and the pap...
Source: Fight Aging! - January 1, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
My Cancer Story
By JEFF GOLDSMITH
On Christmas Eve 2014, I received a present of some profoundly unwelcome news: a 64 slice CT scan confirming not only the presence of a malignant tumor in my neck, but also a fluid filled mass the size of a man’s finger in my chest cavity outside the lungs. Two days earlier, my ENT surgeon in Charlottesville, Paige Powers, had performed a fine needle aspiration of a suspicious almond-shaped enlarged lymph node, and the lab returned a verdict of “metastatic squamous cell carcinoma of the head and neck with an occult primary tumor”.
I had worked in healthcare for nearly forty years when ca...
Source: The Health Care Blog - December 5, 2023 Category: Consumer Health News Authors: matthew holt Tags: Medical Practice The Business of Health Care Cancer Jeff Goldsmith Medicare Advantage Patient Experience Source Type: blogs
Patients are Not “Consumers”: My Cancer Story
By JEFF GOLDSMITH
On Christmas Eve 2014, I received a present of some profoundly unwelcome news: a 64 slice CT scan confirming not only the presence of a malignant tumor in my neck, but also a fluid filled mass the size of a man’s finger in my chest cavity outside the lungs. Two days earlier, my ENT surgeon in Charlottesville, Paige Powers, had performed a fine needle aspiration of a suspicious almond-shaped enlarged lymph node, and the lab returned a verdict of “metastatic squamous cell carcinoma of the head and neck with an occult primary tumor”.
I had worked in healthcare for nearly forty years when ca...
Source: The Health Care Blog - December 5, 2023 Category: Consumer Health News Authors: matthew holt Tags: Medical Practice The Business of Health Care Cancer Jeff Goldsmith Medicare Advantage Patient Experience Source Type: blogs
Zealous for Wellness: The Ongoing Quest for Standard Measures
The previous articles in this series showed how payers, providers, and digital health companies try to prove that they’re helping to create healthier patients. Sara Shanti, a partner specializing in health care at law firm Sheppard Mullin, says that organizations in the wellness space are searching for strong algorithms. But they also want to ensure that technology leads to, and clearly reflects, improved and worthwhile outcomes. This is not likely to emerge for some time. But this final article looks at how some organizations are filling the gap.
Rigor at a Weight Loss Clinic
Dr. Brett Osborn, author of the book G...
Source: EMR and HIPAA - November 16, 2023 Category: Information Technology Authors: Andy Oram Tags: AI/Machine Learning Ambulatory Analytics/Big Data Clinical Communication and Patient Experience Health IT Company Healthcare IT Hospital - Health System LTPAC Arcadia Behavior Change behavioral health BPCI Brett Osborn Clinical Source Type: blogs
Fight Aging! Newsletter, November 13th 2023
This study investigated the correlation among muscle strength, working memory (WM), and cortical hemodynamics during the N-back task of memory performance, and further explored whether cortical hemodynamics during N-back task mediated the relationship between muscle strength and WM performance. We observed that muscle strength (particularly grip strength) predicted WM of older adults in this cross-sectional study, which validated our hypothesis and expanded on previous research findings. Studies demonstrated that grip strength predicted executive function decline in patients with mild cognitive impairment. Other cross-sect...
Source: Fight Aging! - November 12, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Provoking Greater Stem Cell Activity to Reverse Cartilage Loss in Osteoarthritis
Osteoarthritis is a degenerative joint disease characterized by loss of cartilage and associated bone tissue. It is a major, widespread issue in old age. A promising study in mice here suggests that osteoarthritis might be reversed via suitable manipulation of stem cell and progenitor cell populations capable of producing cartilage regrowth. In this model, the known contributing factors, such as chronic inflammation in and around joint tissues, are contributing factors because they suppress the activity of the small population of cells responsible for maintenance of cartilage.
Osteoarthritis is the degeneration of...
Source: Fight Aging! - November 7, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
3D Printing In Medicine And Healthcare – The Ultimate List
3D printing has demonstrated huge potential for the future of medicine in the previous years, and its development is unstoppable. See the impressive list of 3D-printed healthcare materials and medical equipment below!
How does 3D printing in medicine work?
3D printing in medicine is part of the innovative process called additive manufacturing, which means producing three-dimensional solid objects from a digital file. How the technology works, we explained in our article on bioprinting here.
As technology evolves, researchers work on various solutions. For example, engineers from the University of Buffalo have ...
Source: The Medical Futurist - November 7, 2023 Category: Information Technology Authors: berci.mesko Tags: 3D Printing Biotechnology Future of Medicine Healthcare Design Medical Education Personalized Medicine 3d printed biomaterial tissue engineering Video bioprinting GC1 Innovation Source Type: blogs
Lateral Flow Test for Gingivitis
Researchers at the University of Cincinnati have developed a lateral flow assay that can detect bacterial toxins from Porphyromonas gingivalis, the causative bacteria for gingivitis. The technology could make it easier and faster to identify early-stage gingivitis, which can lead to periodontitis and eventual tooth loss, as well as contributing to a variety of other diseases such as stroke and heart disease. The lateral flow assay requires a small saliva sample, and can provide results very quickly, but does require the saliva sample to be pre-treated with potato starch to deactivate salivary amylase, an enzyme that can in...
Source: Medgadget - October 19, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Dentistry Diagnostics gingivitis UofCincy Source Type: blogs
Fight Aging! Newsletter, October 16th 2023
In conclusion, a number of studies have shown that CD4+ Treg cells are crucial in the maintenance of peripheral tolerance and have an important role in the control of atherosclerosis-related inflammation. Therefore, Treg cells are a promising target of major research efforts focused on immune-modulating therapies against atherosclerosis. Developing anti-atherosclerotic Treg-based therapies faces challenges. However, rapid progress in genetic, epigenetic, and molecular aspects of cellular immunology gives hope for a fast-track solution.
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Delivering Senolytic Nanoparticles to Atheroscle...
Source: Fight Aging! - October 15, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Towards More Selective Ways to Block Unwanted Inflammation
Control of chronic inflammation may turn out to be one of the more important themes in the treatment of aging as a medical condition. Senescent cells generate inflammatory signaling, but removing that contribution is likely the easiest aspect of the problem. Many forms of age-related cellular damage and dysfunction generate constant, unwanted, excess inflammation through interactions and signals that are used during a normal, desirable inflammatory reaction, such as to injury or infection. Thus interfering in these mechanisms must be very selective; simply blockading a given signal has undesirable side-effects, such as a w...
Source: Fight Aging! - October 13, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
