DARZALEX FASPRO ® (daratumumab and hyaluronidase-fihj) Becomes the First FDA-Approved Treatment for Patients with Newly Diagnosed Light Chain (AL) Amyloidosis
January 15, 2021 (HORSHAM, Pa.) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today the U.S. Food and Drug Administration (FDA) approval of DARZALEX FASPRO® (daratumumab and hyaluronidase-fihj), a subcutaneous formulation of daratumumab, in combination with bortezomib, cyclophosphamide and dexamethasone (D-VCd) for the treatment of adult patients with newly diagnosed light chain (AL) amyloidosis.[1] DARZALEX FASPRO® is the first and only FDA-approved treatment for patients with this blood cell disorder that is associated with the production of an abnormal protein, which leads to th...
Source: Johnson and Johnson - January 16, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news

Using diagnostic stewardship to reduce rates, healthcare expenditures and accurately identify cases of hospital-onset Clostridioides difficile infection, Infection Control & Hospital Epidemiology 42(1): 51-56
Conclusions: Initiatives to decrease risk for CDI and diagnostic stewardship of C. difficile stool NAAT significantly reduced HO-HCFA CDI rates, detection of potential false-positives associated with laxative use, and lowered healt hcare costs. Diagnostic stewardship itself had the most dramatic impact on outcomes observed and served as an effective tool in reducing HO-HCFA CDI rates. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 15, 2021 Category: Consumer Health News Source Type: news

Mayo Clinic Laboratories Used Ingenuity, Flexibility, and Teamwork to Fast-Track COVID-19 Testing Capacity, Including Hiring Hundreds of Lab Workers
As coronavirus pandemic emerged, the Minnesota reference laboratory surged its testing capacity from 2,600 to 20,000 samples per day in an effort to meet ever-increasing demand Over the past several years, medical laboratory workforce shortages worldwide have challenged clinical laboratory managers to process increasing numbers of clinical laboratory tests with fewer staff. But that did […] The post Mayo Clinic Laboratories Used Ingenuity, Flexibility, and Teamwork to Fast-Track COVID-19 Testing Capacity, Including Hiring Hundreds of Lab Workers appeared first on Dark Daily. (Source: Dark Daily)
Source: Dark Daily - January 15, 2021 Category: Laboratory Medicine Authors: Jude Tags: Laboratory Management and Operations Laboratory News Laboratory Operations Laboratory Pathology Laboratory Testing Management & Operations Amazon Care anatomic pathology clinical laboratory CVS Health Dark Daily dark intelligence gro Source Type: news

Eurofins Bioanalytical Services launches Surrogate Virus Neutralizing...
Eurofins Bioanalytical Services, a member of Eurofins BioPharma Services, Laboratory Testing division, announces the launch of a Surrogate Virus Neutralization Test (sVNT) antibody assay against the...(PRWeb January 15, 2021)Read the full story at https://www.prweb.com/releases/eurofins_bioanalytical_services_launches_surrogate_virus_neutralizing_antibody_detection_assays_against_the_sars_cov_2_covid_19/prweb17629371.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - January 15, 2021 Category: Pharmaceuticals Source Type: news

Incidence of COVID-19 Increased in Children Since September
THURSDAY, Jan. 14, 2021 -- The incidence of laboratory-confirmed COVID-19 increased since September among children, adolescents, and young children, according to research published in the Jan. 13 early-release issue of the U.S. Centers for Disease... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 14, 2021 Category: Pharmaceuticals Source Type: news

Cost Consequences for the NHS of Using a Two-Step Testing Method for the Detection of Clostridium difficile with a Point of Care, Polymerase Chain Reaction Test as the First Step
The two-step, POCT strategy was estimated to save £ 283,282 per 1000 hospitalized NHS patients with suspected infectious diarrhoea. Sensitivity analysis indicated that the turnaround time for the POCT was the largest driver for cost savings. Providing the POCT has sufficiently high diagnostic accuracy for detecting C. difficile, the two-step, POCT strategy for CDI identification is likely to be cost saving for NHS hospitals with an offsite laboratory. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 14, 2021 Category: Consumer Health News Source Type: news

Rapid screening test will help track coronavirus variants in Alberta
Alberta is ramping up its surveillance for two coronavirus variants — which have now been reported in the province — as a team of scientists at the provincial laboratory develop a quicker and easier test to identify cases and determine if and when the strains take root. (Source: CBC | Health)
Source: CBC | Health - January 14, 2021 Category: Consumer Health News Tags: News/Canada/Calgary Source Type: news

Toadlet peptide transforms into a deadly weapon against bacteria
(European Molecular Biology Laboratory) Researchers at the Technion - Israel Institute of Technology and the European Molecular Biology Laboratory in Hamburg have discovered remarkable molecular properties of an antimicrobial peptide from the skin of the Australian toadlet. The discovery could inspire the development of novel synthetic drugs to combat bacterial infections (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 14, 2021 Category: International Medicine & Public Health Source Type: news

Response to Comment on "Boosted molecular mobility during common chemical reactions"
Günther et al. report that their control experiment using randomized magnetic field gradient sequences disagreed with findings we had reported using linear gradients. However, we show that measurements in our laboratory are consistent using both methods. (Source: ScienceNOW)
Source: ScienceNOW - January 14, 2021 Category: Science Authors: Wang, H., Park, M., Dong, R., Kim, J., Cho, Y.-K., Tlusty, T., Granick, S. Tags: t-comment Source Type: news

Johnson & Johnson COVID-19 Vaccine Candidate Interim Phase 1/2a Data Published in New England Journal of Medicine
January 13, 2021 -- Interim Phase 1/2a data were published today in the New England Journal of Medicine demonstrating that the Company’s single-dose investigational COVID-19 vaccine candidate (JNJ-78436735) – being developed by the Janssen Pharmaceutical Companies of Johnson & Johnson – provided an immune response that lasted for at least 71 days, the duration of time measured in this study in participants aged 18-55 years. A preview of part of these interim data was posted on medRxiv in September 2020.The Phase 1/2a interim analysis showed that the Company’s COVID-19 vaccine candidate induced a...
Source: Johnson and Johnson - January 13, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news

DHS and Laboratory Partners Identify Variant Strain B.1.1.7 of SARS-CoV-2 in Wisconsin
On January 12, the Wisconsin Department of Health Services and laboratory partners identified a variant strain of SARS-CoV-2, the virus that causes COVID-19, in Wisconsin. The particular variant, referred to as B.1.1.7, was first discovered circulating widely in England during November and December of 2020. Based on epidemiologic and modeling studies, researchers believe that this new strain spreads more rapidly and easily than the original strain of SARS-CoV-2. However, there is no evidence...(see release) (Source: Wisconsin DHFS Press Releases)
Source: Wisconsin DHFS Press Releases - January 13, 2021 Category: Hospital Management Authors: goodsesjfs Source Type: news

Sudan: Prof Haseeb - Godfather of Sudan's Laboratory Medicine
[SudaNow] Khartoum -- Introducing the book "A Monograph on Biochemical Research in the Sudan" written by the Late Professor Mansour Ali Haseeb, Harry Hoogstraal stated in May 1973 that "Professor Mansour Haseeb has been more intimately associated than any other living person with adding to Sudanese biomedical knowledge and sharing vast experience with younger generations of physicians and scientists. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - January 13, 2021 Category: African Health Source Type: news

Connecticut and Maine to Utilize ‘Episode of Care’ Payment Models for State Employees and Retirees
Also called a ‘bundled payment’ model, under this plan, hospitals and clinical laboratories will receive ‘lump sums’ for certain healthcare procedures Employers and insurers continue to move healthcare providers away from fee-for-service (FFS) payment models and toward value-based reimbursement arrangements, also called Pay for Performance or bundled-payment models. While intended to save money, such payment […] The post Connecticut and Maine to Utilize ‘Episode of Care’ Payment Models for State Employees and Retirees appeared first on Dark Daily. (Source: Dark Daily)
Source: Dark Daily - January 13, 2021 Category: Laboratory Medicine Authors: Jude Tags: Laboratory Management and Operations Laboratory News Laboratory Operations Laboratory Pathology Laboratory Testing Management & Operations AlphaFold anatomic pathology Andrei Lupas PhD Andriy Kryshtafovych PhD Arthur D. Levinson PhD Source Type: news

Fast-growing Covington company receives $20M line of credit as it eyes IPO
Gravity Diagnostics, a Covington-based laboratory that ’s making big moves amid Covid-19, received a multi-million dollar capital infusion from a big-name banking partner as it looks to expand its capacity in 2021 (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - January 13, 2021 Category: Pharmaceuticals Authors: Liz Engel Source Type: news

Getting romantic at home wearing an EEG cap
(Ruhr-University Bochum) Research into the neuronal basis of emotion processing has so far mostly taken place in the laboratory, i.e. in unrealistic conditions. Bochum-based biopsychologists have now studied couples in more natural conditions. Using electroencephalography (EEG), they recorded the brain activity of romantic couples at home while they cuddled, kissed or talked about happy memories together. The results confirmed the theory that positive emotions are mainly processed in the left half of the brain. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - January 13, 2021 Category: International Medicine & Public Health Source Type: news

Shine on: Avalanching nanoparticles break barriers to imaging cells in real time
(DOE/Lawrence Berkeley National Laboratory) A team of researchers co-led by Berkeley Lab and Columbia University has developed a new material called avalanching nanoparticles that, when used as a microscopic probe, offers a simpler approach to taking high-resolution, real-time snapshots of a cell's inner workings at the nanoscale. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - January 13, 2021 Category: Biology Source Type: news

China rewrites COVID history, purges 300 studies linking virus to Wuhan lab
(Natural News) The Chinese Communist Party (CCP) is on a purging spree trying to scrub all links between the Wuhan coronavirus (COVID-19) and the Wuhan Institute of Virology laboratory where it originated from everywhere such evidence exists. According to the latest reports, the CCP has already removed some 300 studies from the National Natural Science... (Source: NaturalNews.com)
Source: NaturalNews.com - January 13, 2021 Category: Consumer Health News Source Type: news

WCCT Global Expands Clinical and Lab Services Capacity to Meet...
WCCT Global, Inc., a Contract Research Organization, or CRO, specializing in early phase clinical trials, is expanding its Orange County based clinical pharmacology unit and laboratory capacity to...(PRWeb January 13, 2021)Read the full story at https://www.prweb.com/releases/wcct_global_expands_clinical_and_lab_services_capacity_to_meet_increasing_demand_for_phase_1_and_covid_19_vaccine_clinical_trials/prweb17651032.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - January 13, 2021 Category: Pharmaceuticals Source Type: news

Enhanced oral uptake of exosomes opens cell therapy alternative
(Cedars-Sinai Medical Center) Cell-derived exosomes are effective in treating disease when mixed with the dominant protein in breast milk and given orally, a new Smidt Heart Institute study of laboratory mice shows. The findings, published in the peer-reviewed Journal of Extracellular Vesicles, could help develop new oral medications for treating patients with muscular dystrophy and heart failure. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 12, 2021 Category: International Medicine & Public Health Source Type: news

EMBL becomes newest Instruct Centre
(European Molecular Biology Laboratory) A major advance for structural biology provision within Europe has been achieved as Instruct-ERIC and EMBL join forces to launch Instruct Centre EMBL. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - January 12, 2021 Category: Biology Source Type: news

The odd structure of ORF8: Mapping the coronavirus protein linked to disease severity
(DOE/Lawrence Berkeley National Laboratory) A team of biologists who banded together to support COVID-19 science determined the atomic structure of a coronavirus protein thought to help the pathogen evade and dampen response from human immune cells. The structural map - which is now published in the journal PNAS, but has been open-access for the scientific community since August - has laid the groundwork for new antiviral treatments and enabled further investigations into how the newly emerged virus ravages the human body. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 12, 2021 Category: International Medicine & Public Health Source Type: news

A reappraisal of childhood drowning in a pediatric emergency department - Şık N, Şenol HB, Öztürk A, Yılmaz D, Duman M.
BACKGROUND: In the present study, we aimed to investigate the demographic and clinical features, laboratory and radiologic characteristics, management, and outcomes of pediatric drowning patients in order to identify predictors of hospital admission, and... (Source: SafetyLit)
Source: SafetyLit - January 11, 2021 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Social facilitation of alcohol subjective effects in adolescents: associations with subsequent alcohol use - Kirkpatrick MG, Cho J, Stone MD, Bae D, Barrington-Trimis JL, Pang RD, Leventhal AM.
RATIONALE: Laboratory research in adults indicates that alcohol-related subjective effects are enhanced under some social conditions. However, it is unknown whether this "social facilitation" of alcohol effects occurs in adolescents and is associated wit... (Source: SafetyLit)
Source: SafetyLit - January 11, 2021 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Walmart, Quest Diagnostics, and DroneUp Collaborate on Pilot Project to Deliver COVID-19 Laboratory Tests to Consumers in Select Cities
Coronavirus pandemic expected to spur wider acceptance of drone delivery services for clinical laboratory specimens and medical supplies Routine delivery of clinical laboratory specimens and medical supplies by drone moved one step closer to reality with news that Walmart (NYSE:WMT), Quest Diagnostics (NYSE:DGX), and DroneUp of Virginia Beach, Va., are partnering to bring at-home self-collection […] The post Walmart, Quest Diagnostics, and DroneUp Collaborate on Pilot Project to Deliver COVID-19 Laboratory Tests to Consumers in Select Cities appeared first on Dark Daily. (Source: Dark Daily)
Source: Dark Daily - January 11, 2021 Category: Laboratory Medicine Authors: Jude Tags: Laboratory Instruments & Laboratory Equipment Laboratory Management and Operations Laboratory News Laboratory Operations Laboratory Pathology Laboratory Testing Management & Operations Amanda Jenkins Amazon Prime Air anatomic pathology Source Type: news

Top government official says China lab leak "most credible" source of coronavirus outbreak
(Natural News) Matthew Pottinger, President Donald Trump’s respected Deputy National Security Adviser, told politicians from around the world during a recent meeting that the most likely source of the Wuhan coronavirus (COVID-19) is a Chinese laboratory. Rather than emerging at a Wuhan wet market as was initially claimed, the Chinese virus more than likely came... (Source: NaturalNews.com)
Source: NaturalNews.com - January 10, 2021 Category: Consumer Health News Source Type: news

More asymptomatic testing can be a vital tool to stop the spread of Covid | Susan Hopkins
Local authorities are being called on to expand their plans as well as to support people who need to self-isolateCoronavirus - latest coverageSee all our coronavirus coverageWe now know that around one in three people who have coronavirusnever show any symptoms but that does not mean they are not infectious. We need to use everything at our disposal to find these individuals without symptoms and support them and their contacts to isolate in order to break the chains of transmission.That is why thecommunity testingoffer is being expanded to all local authorities with a particular focus on workplace testing. This expansion w...
Source: Guardian Unlimited Science - January 9, 2021 Category: Science Authors: Susan Hopkins Tags: Coronavirus Infectious diseases Science UK news Source Type: news

Seeding the Ocean: Inside a Michelin-Starred Chef ’s Revolutionary Quest to Harvest Rice From the Sea
There are very few things that Ángel León hasn’t done with the fruits of the sea. In 2008, as a young, unknown chef, he took a loin from one fish and attached it to the loin of another, using collagen to bind the two proteins together. He called them hybrids and served them to unsuspecting diners at Aponiente, his restaurant in the southern Spanish port town of El Puerto de Santa María, just across the bay from Cádiz. He discovered that fish eyes, cooked at 55°C in a thermal circulator until the gelatin collapsed, made excellent thickening agents for umami-rich sauces. Next he found th...
Source: TIME: Science - January 9, 2021 Category: Science Authors: Matt Goulding Tags: Uncategorized climate change feature longform Magazine Source Type: news

Sacramento (CA) Firefighters Get Inoculated
Tony Bizjak The Sacramento Bee (MCT) Sacramento’s COVID-19 vaccine program took a notable step forward this week, expanding to include shots for thousands of firefighters and paramedics, the emergency first-responders who treat and transport the most seriously ill COVID-19 patients. The new group represents the third major at-risk cohort being offered access to the shots, following several weeks of shots for hospital workers, including doctors and nurses, and more recently, the first inoculations for residents and staffers of skilled nursing facilities. Faced with delays in the first weeks, health offi...
Source: JEMS Operations - January 8, 2021 Category: Emergency Medicine Authors: JEMS Staff Tags: Coronavirus News News Feed California Medicine Source Type: news

Sacramento (CA) Firefighters Get Inoculated
Tony Bizjak The Sacramento Bee (MCT) Sacramento’s COVID-19 vaccine program took a notable step forward this week, expanding to include shots for thousands of firefighters and paramedics, the emergency first-responders who treat and transport the most seriously ill COVID-19 patients. The new group represents the third major at-risk cohort being offered access to the shots, following several weeks of shots for hospital workers, including doctors and nurses, and more recently, the first inoculations for residents and staffers of skilled nursing facilities. Faced with delays in the first weeks, health offi...
Source: JEMS: Journal of Emergency Medical Services News - January 8, 2021 Category: Emergency Medicine Authors: JEMS Staff Tags: Coronavirus News News Feed California Medicine Source Type: news

Sacramento (CA) Firefighters Get Inoculated
Tony Bizjak The Sacramento Bee (MCT) Sacramento’s COVID-19 vaccine program took a notable step forward this week, expanding to include shots for thousands of firefighters and paramedics, the emergency first-responders who treat and transport the most seriously ill COVID-19 patients. The new group represents the third major at-risk cohort being offered access to the shots, following several weeks of shots for hospital workers, including doctors and nurses, and more recently, the first inoculations for residents and staffers of skilled nursing facilities. Faced with delays in the first weeks, health offi...
Source: JEMS Latest News - January 8, 2021 Category: Emergency Medicine Authors: JEMS Staff Tags: Coronavirus News News Feed California Medicine Source Type: news

Sacramento (CA) Firefighters Get Inoculated
Tony Bizjak The Sacramento Bee (MCT) Sacramento’s COVID-19 vaccine program took a notable step forward this week, expanding to include shots for thousands of firefighters and paramedics, the emergency first-responders who treat and transport the most seriously ill COVID-19 patients. The new group represents the third major at-risk cohort being offered access to the shots, following several weeks of shots for hospital workers, including doctors and nurses, and more recently, the first inoculations for residents and staffers of skilled nursing facilities. Faced with delays in the first weeks, health offi...
Source: JEMS Administration and Leadership - January 8, 2021 Category: Emergency Medicine Authors: JEMS Staff Tags: Coronavirus News News Feed California Medicine Source Type: news

Sacramento (CA) Firefighters Get Inoculated
Tony Bizjak The Sacramento Bee (MCT) Sacramento’s COVID-19 vaccine program took a notable step forward this week, expanding to include shots for thousands of firefighters and paramedics, the emergency first-responders who treat and transport the most seriously ill COVID-19 patients. The new group represents the third major at-risk cohort being offered access to the shots, following several weeks of shots for hospital workers, including doctors and nurses, and more recently, the first inoculations for residents and staffers of skilled nursing facilities. Faced with delays in the first weeks, health offi...
Source: JEMS Patient Care - January 8, 2021 Category: Emergency Medicine Authors: JEMS Staff Tags: Coronavirus News News Feed California Medicine Source Type: news

Sacramento (CA) Firefighters Get Inoculated
Tony Bizjak The Sacramento Bee (MCT) Sacramento’s COVID-19 vaccine program took a notable step forward this week, expanding to include shots for thousands of firefighters and paramedics, the emergency first-responders who treat and transport the most seriously ill COVID-19 patients. The new group represents the third major at-risk cohort being offered access to the shots, following several weeks of shots for hospital workers, including doctors and nurses, and more recently, the first inoculations for residents and staffers of skilled nursing facilities. Faced with delays in the first weeks, health offi...
Source: JEMS Special Topics - January 8, 2021 Category: Emergency Medicine Authors: JEMS Staff Tags: Coronavirus News News Feed California Medicine Source Type: news

Pfizer-BioNTech vaccine appears effective against mutation in new coronavirus variants, study suggests
Pfizer Inc. and BioNTech's COVID-19 vaccine appeared to work against a key mutation in the highly transmissible new variants of the coronavirus discovered in Britain and South Africa, according to a laboratory study conducted by the U.S. drugmaker. (Source: CBC | Health)
Source: CBC | Health - January 8, 2021 Category: Consumer Health News Tags: News/Health Source Type: news

Pfizer Study Suggests Vaccine Works Against Virus Variant
By LAURAN NEERGAARD AP Medical Writer New research suggests that Pfizer’s COVID-19 vaccine can protect against a mutation found in two highly contagious variants of the coronavirus that erupted in Britain and South Africa. Those variants are causing global concern. They both share a common mutation called N501Y, a slight alteration on one spot of the spike protein that coats the virus. That change is believed to be the reason they can spread so easily. Most of the vaccines being rolled out around the world train the body to recognize that spike protein and fight it. Pfizer teamed with researchers from the Un...
Source: JEMS Operations - January 8, 2021 Category: Emergency Medicine Authors: JEMS Staff Tags: AP News Coronavirus Medicine Source Type: news

Pfizer Study Suggests Vaccine Works Against Virus Variant
By LAURAN NEERGAARD AP Medical Writer New research suggests that Pfizer’s COVID-19 vaccine can protect against a mutation found in two highly contagious variants of the coronavirus that erupted in Britain and South Africa. Those variants are causing global concern. They both share a common mutation called N501Y, a slight alteration on one spot of the spike protein that coats the virus. That change is believed to be the reason they can spread so easily. Most of the vaccines being rolled out around the world train the body to recognize that spike protein and fight it. Pfizer teamed with researchers from the Un...
Source: JEMS: Journal of Emergency Medical Services News - January 8, 2021 Category: Emergency Medicine Authors: JEMS Staff Tags: AP News Coronavirus Medicine Source Type: news

Pfizer Study Suggests Vaccine Works Against Virus Variant
By LAURAN NEERGAARD AP Medical Writer New research suggests that Pfizer’s COVID-19 vaccine can protect against a mutation found in two highly contagious variants of the coronavirus that erupted in Britain and South Africa. Those variants are causing global concern. They both share a common mutation called N501Y, a slight alteration on one spot of the spike protein that coats the virus. That change is believed to be the reason they can spread so easily. Most of the vaccines being rolled out around the world train the body to recognize that spike protein and fight it. Pfizer teamed with researchers from the Un...
Source: JEMS Latest News - January 8, 2021 Category: Emergency Medicine Authors: JEMS Staff Tags: AP News Coronavirus Medicine Source Type: news

Pfizer Study Suggests Vaccine Works Against Virus Variant
By LAURAN NEERGAARD AP Medical Writer New research suggests that Pfizer’s COVID-19 vaccine can protect against a mutation found in two highly contagious variants of the coronavirus that erupted in Britain and South Africa. Those variants are causing global concern. They both share a common mutation called N501Y, a slight alteration on one spot of the spike protein that coats the virus. That change is believed to be the reason they can spread so easily. Most of the vaccines being rolled out around the world train the body to recognize that spike protein and fight it. Pfizer teamed with researchers from the Un...
Source: JEMS Administration and Leadership - January 8, 2021 Category: Emergency Medicine Authors: JEMS Staff Tags: AP News Coronavirus Medicine Source Type: news

Pfizer Study Suggests Vaccine Works Against Virus Variant
By LAURAN NEERGAARD AP Medical Writer New research suggests that Pfizer’s COVID-19 vaccine can protect against a mutation found in two highly contagious variants of the coronavirus that erupted in Britain and South Africa. Those variants are causing global concern. They both share a common mutation called N501Y, a slight alteration on one spot of the spike protein that coats the virus. That change is believed to be the reason they can spread so easily. Most of the vaccines being rolled out around the world train the body to recognize that spike protein and fight it. Pfizer teamed with researchers from the Un...
Source: JEMS Patient Care - January 8, 2021 Category: Emergency Medicine Authors: JEMS Staff Tags: AP News Coronavirus Medicine Source Type: news

Pfizer Study Suggests Vaccine Works Against Virus Variant
By LAURAN NEERGAARD AP Medical Writer New research suggests that Pfizer’s COVID-19 vaccine can protect against a mutation found in two highly contagious variants of the coronavirus that erupted in Britain and South Africa. Those variants are causing global concern. They both share a common mutation called N501Y, a slight alteration on one spot of the spike protein that coats the virus. That change is believed to be the reason they can spread so easily. Most of the vaccines being rolled out around the world train the body to recognize that spike protein and fight it. Pfizer teamed with researchers from the Un...
Source: JEMS Special Topics - January 8, 2021 Category: Emergency Medicine Authors: JEMS Staff Tags: AP News Coronavirus Medicine Source Type: news

Lessons Learned Comparing Immune System Alterations of Bacterial Sepsis and SARS-CoV-2 Sepsis. Frontiers in immunology 11: 598404.
Conclusions: There are both similarities and differ ences in the immune system status of bacterial sepsis and SARS-CoV-2 sepsis. Our findings do not support blocking the cytokine storm or supplementing immunoglobulins in SARS-CoV-2 sepsis, at least in the early stages of the disease. Treatments for overactivation of the complement system and lymphocy te depletion may be worth exploring further. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 8, 2021 Category: Consumer Health News Source Type: news

University of Vermont Microbiology Laboratory Identifies Inefficiencies When Performing Pooled Testing for COVID-19
The key to success with pooled testing, says the lab’s director, is having the right personnel and equipment, and an LIS that supports the added steps Experts believe pooled testing for COVID-19 could reduce the number of standard tests for SARS-CoV-2 by conserving testing resources and cutting lab spending on tests and testing supplies. However, […] The post University of Vermont Microbiology Laboratory Identifies Inefficiencies When Performing Pooled Testing for COVID-19 appeared first on Dark Daily. (Source: Dark Daily)
Source: Dark Daily - January 8, 2021 Category: Laboratory Medicine Authors: Jude Tags: Instruments & Equipment International Laboratory News Laboratory Hiring & Human Resources Laboratory Management and Operations Laboratory Operations Laboratory Pathology Laboratory Testing Management & Operations AlphaFold anatomic patho Source Type: news

Bioenergetics: New features of ATP synthase
(Science For Life Laboratory) Structural studies of a mitochondrial ATP synthase illustrate the basis for the diversity of its membrane-shaping properties. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - January 8, 2021 Category: Biology Source Type: news

Study reveals new details about how bacterial toxins cause life-threatening colitis
FINDINGSResearch led by scientists from UCLA and Harvard University has uncovered details about how the bacterium Clostridioides difficile causes excessive inflammation in the gut that can lead to potentially deadly colitis. Studying C. difficile toxin A, one of two toxins released by the bacterium, the researchers produced two key findings.They pinpointed which part of the toxic protein can permeate cell membranes to gain entry to cellular structures called endosomes, demonstrating that even fragments of the protein that contain that key segment are capable of accessing endosomes.In addition, they revealed how the toxin m...
Source: UCLA Newsroom: Health Sciences - January 8, 2021 Category: Universities & Medical Training Source Type: news

MRI frequently underestimates tumor size in prostate cancer
FINDINGSA study led by researchers at theUCLA Jonsson Comprehensive Cancer Center has found that magnetic resonance imaging, or MRI, frequently underestimates the size of prostate tumors, potentially leading to undertreatment.The study authors found that such underestimation occurs most often when the MRI-measured tumor size is small and the PI-RADS score, which is used to classify lesions in prostate MRI analysis, is low.For prostate tumor treatments to be successful, both the MRI size measurement and PI-RADS score must be accurate because they allow physicians to determine precisely where tumors end and where the normal,...
Source: UCLA Newsroom: Health Sciences - January 7, 2021 Category: Universities & Medical Training Source Type: news

Kenya: Medical Laboratory Workers Go On Strike
[Nation] Medical laboratory workers are the latest frontline workers in healthcare to go on strike after the government failed to meet their demands. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - January 7, 2021 Category: African Health Source Type: news

New defense against dengue and emerging mosquito-borne viruses
(University of Queensland) New treatments to cut the global death rate from dengue, Zika and West Nile viruses could result from research led by The University of Queensland. Associate Professor Daniel Watterson from UQ's School of Chemistry and Molecular Biosciences said the team identified an antibody that improved survival rates in laboratory trials and reduced the presence of virus in the blood. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - January 7, 2021 Category: Biology Source Type: news

Covid UK: Daily death toll passes 1,000 for first time since APRIL
Department of Health data shows today's grim figure of 1,041 laboratory-confirmed deaths - only the 10th time the UK has topped the grisly milestone - is UK's highest daily count since April 21. (Source: the Mail online | Health)
Source: the Mail online | Health - January 6, 2021 Category: Consumer Health News Source Type: news

Hematologic Indices as Predictive Parameters for SLE Hematologic Indices as Predictive Parameters for SLE
This study investigated whether hematologic indices such as NLR, PLR, MPV, PDW, and RDW might serve as markers of disease activity in systemic lupus erythematosus.Laboratory Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 6, 2021 Category: Consumer Health News Tags: Pathology & Lab Medicine Journal Article Source Type: news

Healthcare Companies and Health Systems Continue to Grow Through Mergers and Acquisitions Despite COVID-19 Pandemic
Consolidation of hospitals and health systems means consolidated medical laboratory services as well, and that impacts laboratory revenue and staff Though COVID-19 shifted many healthcare systems’ priorities in 2020—including quite dramatically altering the priorities of the nation’s clinical laboratories—the SARS-CoV-2 pandemic does not appear to have slowed the pace of healthcare mergers and acquisitions. Many […] The post Healthcare Companies and Health Systems Continue to Grow Through Mergers and Acquisitions Despite COVID-19 Pandemic appeared first on Dark Daily. (Source: Dark Daily)
Source: Dark Daily - January 6, 2021 Category: Laboratory Medicine Authors: Jude Tags: International Laboratory News Laboratory Hiring & Human Resources Laboratory Management and Operations Laboratory Operations Laboratory Pathology Laboratory Sales and Marketing Management & Operations AlphaFold anatomic pathology Andrei Source Type: news