Developing a Culture of Safety in Biomedical Research Training
The National Institute of General Medical Sciences (NIGMS) is committed to supporting safety in the nation’s biomedical research and training environments. Last April, we shared with you resources for enhancing lab safety in biomedical research training environments. Now, in a Perspective in the current issue of Molecular Biology of the Cell (MBoC), we focus on strategies for improving laboratory safety. Some of these strategies are also applicable to other forms of safety including the prevention of harassment, intimidation, and discrimination. We frame the problem of laboratory safety using a number of recent examp...
Source: NIH Extramural Nexus - October 15, 2020 Category: Research Authors: Michelle Bond, Alison Gammie, and Jon Lorsch Tags: blog Open Mike lab safety NIGMS Training Source Type: funding

Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH2/UH3 Clinical Trial Not Allowed)
Funding Opportunity PAR-20-313 from the NIH Guide for Grants and Contracts. Through this Funding Opportunity Announcement (FOA), the National Cancer Institute (NCI) invites applications to support the validation of molecular/cellular/imaging markers (referred to as "markers" or "biomarkers") and assays for cancer detection, diagnosis, prognosis, monitoring, and prediction of response or resistance to treatment, as well as markers for cancer prevention and control. This FOA will support investigator-initiated research for both analytical, and clinical validation of assays to be used in cancer treatment,...
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 13, 2020 Category: Research Source Type: funding

Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH3 Clinical Trials Not Allowed)
Funding Opportunity PAR-20-314 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to accelerate the adoption and validation of molecular/cellular/imaging markers (referred to as "markers" or "biomarkers") and assays for cancer detection, diagnosis, prognosis, monitoring, and prediction of response or resistance to treatment, as well as markers for cancer prevention and control. This FOA will also support the validation of pharmacodynamic markers and markers of toxicity. Applicants to this FOA must have an assay(s) whose performance has been analyt...
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 13, 2020 Category: Research Source Type: funding

Reminder: Annual Reports to the Office of Laboratory Animal Welfare due December 1, 2020
Notice NOT-OD-21-003 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 1, 2020 Category: Research Source Type: funding

Proposals for Community Instruments and Facilities (CIF)
Letter of Intent Deadline Date: October 21, 2020 Program Guidelines: NSF 20-596The intent of the Community Instruments and Facilities (CIF) solicitation is to provide the NSF-sponsored atmospheric sciences research community with access to specialized instrumentation for field and laboratory-based studies.  The CIF solicitation requests proposals from instrument and facility providers who will make their equipment available for community use through an NSF-defined request process.  Support will be provided for limited technician time, minor ...More at https://www.nsf.gov/funding/pgm_summ.jsp?pims_id=505...
Source: NSF Upcoming Due Dates - September 21, 2020 Category: Science Source Type: funding

Case Study in Review Integrity: Abuse of Power
A series to raise awareness, encourage dialog and inspire creative problem solving for challenges in maintaining integrity in peer review. What would you do if, as the Dean of Research at a major university, a group of students, postdocs, and junior faculty reported that they had been pressured into writing reviewer critiques for a senior faculty member? We were so impressed by the careful handling of just such a situation by an institutional official recently that we wanted to share this story with you (we’ve changed details and fictionalized names). Dr. Lee, Dean of Research at a major research university,...
Source: NIH Extramural Nexus - September 2, 2020 Category: Research Authors: Mike Lauer Tags: blog Open Mike Confidentiality Peer review Source Type: funding

NCI Research Specialist (Laboratory-based Scientist) Award (R50 Clinical Trial Not Allowed)
Funding Opportunity PAR-20-288 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites grant applications for the Research Specialist Award (R50) in any area of NCI-funded cancer research. This FOA is specifically for laboratory-based scientists. The Research Specialist Award is designed to encourage the development of stable research career opportunities for exceptional scientists who want to continue to pursue research within the context of an existing NCI-funded basic, translational, clinical, or population science cancer research program, but not serve as independent investigat...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 26, 2020 Category: Research Source Type: funding

Notice of Participation in RFA-OD-20-023, "Emergency Awards: RADx-rad Predicting Viral-Associated Inflammatory Disease Severity in Children with Laboratory Diagnostics and Artificial Intelligence (PreVAIL kIds) (R61/R33 Clinical Trial Optional)"
Notice NOT-TR-20-034 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 21, 2020 Category: Research Source Type: funding

Validation Studies of Analytical Methods for Dietary Supplement Constituents (Admin Supp - Clinical Trial Not Allowed)
Funding Opportunity PA-20-252 from the NIH Guide for Grants and Contracts. The rigor and reproducibility of research on dietary supplements is enhanced by rigorous characterization of key experimental resources and biological samples. The dissemination of analytical methods that are validated to accurately and reliably characterize dietary supplements and quantify their constituents and/or metabolites is vital for both basic and clinical research. This FOA builds on existing NIH awards to support the performance and publication of formal single-laboratory validation studies of analytical methods for dietary supplements an...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 30, 2020 Category: Research Source Type: funding

An Early Look at Applications Submitted During the Pandemic
It has been four months since the COVID-19 pandemic shuttered laboratories and clinical studies across the country and the world.  On April 10, only a few weeks into the pandemic, the Congressional Research Service (CRS) published a report on the “Effects of COVID-19 on the Federal Research and Development Enterprise.”  The report described the consequences of social distancing and other pandemic mitigation measures.  These consequences included laboratory closures, de-prioritized projects, cancellation of meetings and conferences, loss of revenue, disrupted personnel processes (e.g. graduation, ...
Source: NIH Extramural Nexus - July 28, 2020 Category: Research Authors: Mike Lauer Tags: blog Open Mike coronavirus COVID-19 Funding data Source Type: funding

New Vertebrate Animals Section Training Module
Calling all applicants proposing research with vertebrate animals – check out the latest online learning module on the Vertebrate Animals Section in grant applications. This interactive module will assist applicants and offerors in preparing this section of the application, and will serve as a valuable resource for reviewers in evaluating the Vertebrate Animal Section of applications and proposals. This engaging module takes 30 minutes or less to complete and includes: an overview of the requirements, a checklist for applicants and reviewers, detailed instructions, and responsibilities of applicants...
Source: NIH Extramural Nexus - July 24, 2020 Category: Research Authors: NIH Staff Tags: New Resources Animal Welfare OLAW Training Source Type: funding

Useful Flexibilities for Animal Care and Use Programs to Comply with the PHS Policy During the COVID-19 Pandemic
As we continue to address the effects of COVID-19 and as some states and institutions are considering reopening, we would like to share some administrative flexibilities that NIH is providing to research institutions with laboratory animal programs. These flexibilities are meant to assure personnel safety and animal welfare while enabling research personnel to prioritize and preserve research efforts. Some of these can be useful in reducing administrative burden, too. My colleagues with the NIH Office of Laboratory Animal Welfare (OLAW), Drs. Catharine Pritchard, Nicolette Petervary, and Neera Gopee, described these ad...
Source: NIH Extramural Nexus - July 20, 2020 Category: Research Authors: Mike Lauer Tags: blog Open Mike Animal Welfare COVID-19 OLAW Source Type: funding

Addressing Foreign Interference and Associated Risks to the Integrity of Biomedical Research, and How You Can Help
On Tuesday, June 23, Dr. Kelvin Drogemeier, the Director of the Office of Science and Technology Policy (OSTP), gave a presentation to the Federal Demonstration Partnership (FDP) on “Enhancing the Security and Integrity of America’s Research Enterprise.”  Dr. Drogemeier articulated five “key takeaway” messages: The integrity of our research enterprise rests upon core principles and values, including transparency, honesty, accountability, objectivity, respect, freedom of inquiry, reciprocity, and merit-based competition;Principled international collaboration and foreign contributions ar...
Source: NIH Extramural Nexus - July 8, 2020 Category: Research Authors: Mike Lauer Tags: blog Open Mike other support Research integrity Source Type: funding

Pediatric Biospecimen Procurement Center (BPC) Supporting the Developmental Gene Expression (dGTEx) Project (U24 Clinical Trial Not Allowed)
Funding Opportunity RFA-HD-21-008 from the NIH Guide for Grants and Contracts. The NIH is coordinating efforts for establishing a developmental Genotype-Tissue Expression (dGTEx) project, to catalog and analyze transcriptional profiles from a wide variety of tissues obtained from neonates, children, and adolescents in a post-mortem setting. The purpose of this funding opportunity is for support of a Biospecimen Procurement Center (BPC) to enroll suitable pediatric donors and provide high quality tissue samples for analyses to the Laboratory, Data Analysis, and Coordinating Center (LDACC). The BPC will work closely with th...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 23, 2020 Category: Research Source Type: funding

Laboratory, Data Analysis, and Coordinating Center (LDACC) for the Developmental Genotype-Tissue Expression Project(U24) (Clinical Trial Not Allowed)
Funding Opportunity RFA-HG-20-039 from the NIH Guide for Grants and Contracts. The National Human Genome Research Institute (NHGRI) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development are coordinating efforts for establishing a Developmental Genotype-Tissue Expression (dGTEx) project, to catalog and analyze transcriptional profiles from a wide variety of tissues obtained from neonates, children, and adolescents in a post-mortem setting. The purpose of this FOA is to solicit applications to develop and implement a Laboratory, Data Analysis, and Coordinating Center (LDACC) for the Develop...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 19, 2020 Category: Research Source Type: funding

Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access (X01)
Funding Opportunity PAR-20-230 from the NIH Guide for Grants and Contracts. The Center for Inherited Disease Research (CIDR) high-throughput genotyping, sequencing and supporting statistical genetics services are designed to aid the identification of genes or genetic modifications that contribute to human health and disease or to enhance existing collections of well-phenotyped specimens by the addition of genotype or next-generation sequence data. The laboratory specializes in genomic services that cannot be efficiently carried out in individual investigator laboratories. CIDR provides the most up-to-date platforms, servi...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 11, 2020 Category: Research Source Type: funding

Emergency Awards: SARS-CoV-2 Serological Sciences Centers of Excellence (U54 Clinical Trial Optional)
Funding Opportunity RFA-CA-20-038 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) is associated with the COVID-19 Supplement funded through the Paycheck Protection Program and Health Care Enhancement Act (P.L. 116-139) which directs the National Cancer Institute of the NIH to develop, validate, improve, and implement serological testing and associated technologies . The purpose of the FOA is to establish Serological Sciences Centers of Excellence with the goal of identifying and advancing research opportunities to characterize the immune responses elicited by SARS-CoV-2 viral infec...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 5, 2020 Category: Research Source Type: funding

Emergency Awards: Research Projects in SARS-CoV-2 Serological Sciences (U01 Clinical Trial Optional)
Funding Opportunity RFA-CA-20-039 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) is associated with the COVID-19 Supplement funded through the Paycheck Protection Program and Health Care Enhancement Act (P.L. 116-139) which directs the National Cancer Institute of the NIH to develop, validate, improve, and implement serological testing and associated technologies. The purpose of the FOA is to establish Serological Sciences Research Projects with the goals of: identifying and advancing research opportunities to characterize the immune responses elicited by SARS-CoV-2 viral infectio...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 5, 2020 Category: Research Source Type: funding

Animal Oversight Changes for Institutions Receiving National Aeronautics and Space Administration (NASA) Funding
On April 16, 2020, NIH and the National Aeronautics and Space Administration (NASA) announced a new agreement to ensure consistent and effective oversight of the welfare of animals used in NASA-funded activities. The agreement provides a framework to enhance communication and harmonize the agencies’ efforts while reducing regulatory burden to supported institutions. According to this agreement, institutions receiving NASA funding will need to: include NASA-supported activities with live vertebrate animals as covered activities in their PHS Animal Welfare Assurance (Assurance), andpromptly report situatio...
Source: NIH Extramural Nexus - April 30, 2020 Category: Research Authors: NIH Staff Tags: Animal Welfare Top Stories laboratory animal OLAW Source Type: funding

Notice of Memorandum of Understanding Between NIH and NASA Concerning Laboratory Animal Welfare
Notice NOT-OD-20-095 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 16, 2020 Category: Research Source Type: funding

Supporting Tribal Public Health Capacity in Coronavirus Preparedness and Response
Non-competitive grants for Tribal governments and Tribal organizations to carry out public health emergency response activities in response to COVID-19. Activities may include surveillance, epidemiology, laboratory capacity, infection control, mitigation, communications, and other preparedness and response activities. Geographic coverage: Nationwide -- Centers for Disease Control and Prevention, U.S. Department of Health and Human Services (Source: Funding opportunities via the Rural Health Information Hub)
Source: Funding opportunities via the Rural Health Information Hub - April 6, 2020 Category: American Health Source Type: funding

Limited Competition: National Biocontainment Laboratories (NBLs) Operations Support (UC7 Clinical Trial Not Allowed)
Funding Opportunity RFA-AI-20-026 from the NIH Guide for Grants and Contracts. The goal of this Funding Opportunity Announcement (FOA) is to continue to provide operations support for Biosafety Level 4 (BSL4) facilities to the National Biocontainment Laboratories at the University of Texas Medical Branch (UTMB) in Galveston, Texas and Boston University in Boston, Massachusetts. Operations support is provided in the following areas: facility maintenance and operations; biosecurity; environmental health and safety regulations and requirements; regulatory compliance; and specialized research support services. The NBLs will s...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 6, 2020 Category: Research Source Type: funding

Special Topic Research Education Course: Exploring Auditory and Vestibular Biology (R25 - Clinical Trial Not Allowed)
Funding Opportunity RFA-DC-20-001 from the NIH Guide for Grants and Contracts. The over-arching goal of this NIDCD R25 program is to support educational activities that foster a better understanding of biomedical research and its implications in the areas of auditory and vestibular research. The complexity of auditory and vestibular biology processes provide our hearing and balance function. Interruption of these processes may occur from a variety of factors, including genetic, environmental and pathogenic agents, and often results in the loss of hearing and balance function. While loss or impairment of these functions ar...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 23, 2020 Category: Research Source Type: funding

Flexibilities for Assured Institutions for Activities of Institutional Animal Care and Use Committees (IACUCs) Due to COVID-19
The NIH Office of Laboratory Animal Welfare (OLAW) is deeply concerned about the impact of the expanding outbreak of the respiratory illness, COVID-19, on the ability of Assured institutions to support the well-being of animals and personnel during this public health emergency. See NOT-OD-20-088 for flexibilities provided in the Public Health Service (PHS) Policy on Humane Care and Use of Laboratory Animals (Policy) that are applicable to implementing a pandemic plan for animal care and use programs.  (Source: NIH Extramural Nexus)
Source: NIH Extramural Nexus - March 17, 2020 Category: Research Authors: NIH Staff Tags: Policy Top Stories Source Type: funding

NSF Innovation Corps Hubs Program (I-CorpsTM Hubs)
Full Proposal Deadline Date: April 14, 2020 Program Guidelines: NSF 20-529The National Science Foundation (NSF) seeks to further develop and nurture a national innovation ecosystem that guides the output of scientific discoveries closer to the development of technologies, products, and services that benefit society. The goal of the NSF Innovation Corps (I-Corps) Program, created in 2011 by NSF, has been and will continue to be to reduce the time and risk associated with translating promising ideas and technologies from the laboratory to the ...More at https://www.nsf.gov/funding/pgm_summ.jsp?pims_id=505760&WT.mc_id=USN...
Source: NSF Upcoming Due Dates - March 15, 2020 Category: Science Source Type: funding

Rural Experiences for Health Professions Students Summer Experience Program
A program that places clinical psychology, master of social work, physician, physician assistant, medical laboratory science, nurse practitioner, pharmacy, nursing, physical and occupational therapy students from South Dakota in a 4-week experience with preceptors established in rural or frontier areas of South Dakota. Geographic coverage: South Dakota -- Yankton Rural Area Health Education Center (Source: Funding opportunities via the Rural Health Information Hub)
Source: Funding opportunities via the Rural Health Information Hub - March 2, 2020 Category: American Health Source Type: funding

Maximizing Investigators Research Award (MIRA) for Early Stage Investigators (R35 - Clinical Trial Optional)
Funding Opportunity PAR-20-117 from the NIH Guide for Grants and Contracts. The Maximizing Investigators' Research Award (MIRA) under this FOA is a grant to provide support for a program of research in an early stage investigator's laboratory that falls within the mission of NIGMS. For the purpose of this FOA, a program of research is a collection of projects in the investigator's lab that are relevant to the mission of NIGMS. The goal of MIRA is to increase the efficiency and efficacy of NIGMS funding. It is anticipated that this FOA will: Enable investigators to apply earlier in their independent research careers, allow...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 24, 2020 Category: Research Source Type: funding

Notice of Special Interest (NOSI): Administrative Supplements to Enhance Laboratory Safety Curriculum and a Culture of Safety in Biomedical Research Training Environments
Notice NOT-GM-20-016 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 13, 2020 Category: Research Source Type: funding

Animal and Biological Material Resource Centers (P40) (Clinical Trials Not-Allowed)
Funding Opportunity RFA-OD-20-002 from the NIH Guide for Grants and Contracts. This FOA encourages grant applications for national Animal and Biological Material Resource Centers. These Centers provide support for special colonies of laboratory animals, as well as other resources such as informatics tools, reagents, cultures (cells, tissues, and organs) and genetic stocks that serve the biomedical research community in a variety of research areas on a local, regional, and national basis. The important mission of the projects described by this FOA is to provide research resources, which are facilitating the optimization an...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 8, 2020 Category: Research Source Type: funding

Mechanisms of Rejuvenation and Age-Acceleration in Heterochronic Blood Exchange (R01 Clinical Trial Not Allowed)
The objectives are to identify the multiple factors involved, the multiple cell types involved and the mechanisms underlying rejuvenation or accelerated aging that is observed in the transfer of phenotypes between young and old laboratory animals. It is also anticipated that molecular signatures of rejuvenation or accelerated aging will be obtained from research supported under this FOA. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 17, 2019 Category: Research Source Type: funding

Revision Applications for Validation of Biomarker Assays Developed Through NIH-Supported Research Grants (R01 Clinical Trial Not Allowed)
Funding Opportunity PAR-20-074 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to accelerate the pace of translation of NCI-supported methods/assays/technologies (referred to as "assays") to the clinic. Specifically, the focus of this FOA is on the adaption and clinical validation of molecular/cellular/imaging markers (referred to as "markers" r "biomarkers") for cancer detection, diagnosis, prognosis, monitoring, and prediction of response in treatment, as well as markers for cancer control and prevention. Research applications may s...
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 10, 2019 Category: Research Source Type: funding

National Centers for Translational Research in Reproduction and Infertility (NCTRI) (P50 Clinical Trial Optional)
Funding Opportunity RFA-HD-21-012 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to announce the re-competition of the National Centers for Translational Research in Reproduction and Infertility (NCTRI). The NCTRI will be administered through the Specialized Research Center (P50) award mechanism. These centers will form a national network that facilitates and accelerates bidirectional knowledge transfer between the laboratory and clinic with the ultimate goal of improving human reproductive health through research excellence and innovation. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 4, 2019 Category: Research Source Type: funding

New Approaches for Incorporating Genetic Diversity into Toxicity Testing (R43/R44 Clinical Trial Not Allowed)
Funding Opportunity RFA-ES-20-008 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) supports Phase I (R43), Direct to Phase II (R44), and Fast Track (R44) Small Business Innovative Research (SBIR) grant proposals from small businesses concerns (SBCs) to develop resources and approaches, including panels of cells or model organisms, that can better reflect the variability in human populations in chemical toxicity testing. Current toxicology testing is often limited to studies conducted in a small number of laboratory rodent strains, which can fail to identify clinically relevant toxic...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 27, 2019 Category: Research Source Type: funding

Reminder: Annual Reports to the Office of Laboratory Animal Welfare due January 31, 2020
Notice NOT-OD-20-027 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 19, 2019 Category: Research Source Type: funding

Limited Competition: Competitive Supplement to the Coordinating Center for Type 1 Diabetes TrialNet (U01 Clinical Trial Required)
Funding Opportunity RFA-DK-19-506 from the NIH Guide for Grants and Contracts. Type 1 diabetes (T1D) is a serious and burdensome chronic disease that usually onsets in childhood or early adulthood. Recent progress in clinical trials and understanding of T1D pathogenesis and mechanisms have created opportunities to delay the onset and progression of the disease. This supplement is intended to provide resources for the design and conduct of new intervention studies in individuals at early pre-clinical stages of T1D and in individuals with new-onset T1D through the T1D TrialNet network (TrialNet). This Funding Opportunity An...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 14, 2019 Category: Research Source Type: funding

Limited Competition: Competitive Supplement to the Coordinating Center for Type 1 Diabetes TrialNet (U01 Clinical Trial Required)
Type 1 diabetes (T1D) is a serious and burdensome chronic disease that usually onsets in childhood or early adulthood. Recent progress in clinical trials and understanding of T1D pathogenesis and mechanisms have created opportunities to delay the onset and progression of the disease. This supplement is intended to provide resources for the design and conduct of new intervention studies in individuals at early pre-clinical stages of T1D and in individuals with new-onset T1D through the T1D TrialNet network (TrialNet). This Funding Opportunity Announcement (FOA) invites an application from the Program Director/Principal Inve...
Source: NIDDK Funding Opportunities - November 14, 2019 Category: Endocrinology Source Type: funding

Cancer Center Support Grants (CCSGs) for NCI-designated Cancer Centers (P30 Clinical Trial Optional)
Funding Opportunity PAR-20-043 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications for P30 Cancer Center Support Grants (CCSGs) to support NCI-designated Cancer Centers. CCSGs support two types of cancer centers: 1) Comprehensive Cancer Centers, which demonstrate reasonable depth and breadth of research activities in each of three major areas: basic laboratory; clinical; and prevention, control and population-based research, and which have substantial transdisciplinary research that bridges these scientific areas; and 2) Cancer Centers, which are primarily focused ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 4, 2019 Category: Research Source Type: funding

NINDS Ruth L. Kirschstein National Research Service Award (NRSA) for Training of Postdoctoral Fellows (F32 Clinical Trial Not Allowed)
Funding Opportunity PAR-20-021 from the NIH Guide for Grants and Contracts. (Reissue of PAR-16-458) The purpose of this award is to support outstanding scientific training of highly promising postdoctoral candidates with outstanding mentors. Candidates are eligible to apply for support from this program from ~12 months prior to the start of the proposed postdoctoral position to within 12 months after starting in postdoctoral position. Based on the early timeframe of eligibility, and the discouragement of inclusion of preliminary data, this NINDS F32 seeks to foster early, goal-directed planning and to encourage applicatio...
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 18, 2019 Category: Research Source Type: funding

Integrative Research on Polysubstance Abuse and Disorder (R61/R33 Clinical Trial Optional)
Funding Opportunity PAR-20-035 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) is supported by Collaborative Research on Addiction (CRAN) at the National Institutes of Health (NIH), a trans-NIH partnership composed of the National Institute on Alcohol Abuse and Alcoholism (NIAAA), the National Institute on Drug Abuse (NIDA), and the National Cancer Institute (NCI). The intent of this FOA is two-fold: (1) characterize how the neurobiological alterations, associated behaviors, and public health consequences arising from polysubstance use differ from, or are similar to, those observed...
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 18, 2019 Category: Research Source Type: funding

Final Report on Reducing Administrative Burdens Associated with Research Involving Laboratory Animals
This report, called for in the 21st Century Cures Act, is the culmination of more than two years of diligent work to address inconsistent and overlapping policies governing oversight of research involving animals, while ensuring research findings remain credible and research institutions safeguard animal welfare.  Regulations and policies overseeing federally-sponsored research help ensure NIH remains a responsible steward of public funds. This extends to properly enforcing the public’s expectation on how laboratory animals will be used in biomedical research, teaching, and testing. Many stakeholders have po...
Source: NIH Extramural Nexus - September 25, 2019 Category: Research Authors: Mike Lauer Tags: blog Open Mike Administrative Burden Animal Welfare Source Type: funding

Limited Competition: Pediatric Brain Tumor Consortium (UM1 Clinical Trials Required)
Funding Opportunity RFA-CA-19-059 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) is intended to continue support for the Pediatric Brain Tumor Consortium (PBTC). This Limited-Competition FOA solicits a single application from the current PBTC awardee. The PBTC was conceived as a dedicated clinical trials organization able to translate innovative therapies from the laboratory to early phase clinical testing so that treatment for primary brain tumors in children can be improved. The importance of the PBTC is highlighted by the continuing high mortality rate among some common brain t...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 23, 2019 Category: Research Source Type: funding

Resource-Related Research Projects for Development of Animal Models and Related Materials (R24 Clinical Trials Not-Allowed)
Funding Opportunity RFA-OD-19-027 from the NIH Guide for Grants and Contracts. The Office of Research Infrastructure Programs (ORIP) encourages grant applications aimed at developing, characterizing or improving animal models of human diseases; improving access to information about or generated from the use of animal models of human disease; or improving diagnosis and control of diseases of laboratory animals. The animal models and related materials developed must have broad application to multiple NIH Institutes or Centers (ICs) to align with the ORIPs trans-NIH mission. Applications must describe the need and potential ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 11, 2019 Category: Research Source Type: funding

Maximizing Investigators' Research Award (R35 - Clinical Trial Optional)
Funding Opportunity PAR-19-367 from the NIH Guide for Grants and Contracts. The Maximizing Investigators' Research Award (MIRA) provides support for the program of research in an investigator's laboratory that is within the mission of NIGMS. The goal of MIRA is to increase the efficiency and efficacy of NIGMS funding. It is anticipated that this program will: Increase the stability of funding for NIGMS-supported investigators, which could enhance their ability to take on ambitious scientific projects and approach problems more creatively; Increase flexibility for investigators to follow important new research directions w...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 9, 2019 Category: Research Source Type: funding

Thoughts on How Institutions Can Promote a Culture of Research Integrity
On May 22, I had the privilege of participating in a terrific national conference that focused on what institutions can do to foster a culture of research integrity (see the agenda here).  The DHHS Office of Research Integrity (ORI), Northwestern University, and the Council of Graduate Schools hosted the conference, “The Role of Research Integrity in Promoting Excellence: Tools for Colleges and University Leaders.”  The conference organizers’ goal was “to engage university and college leaders in lively discussions about strategies, resources, and tools for promoting research integrity for ...
Source: NIH Extramural Nexus - August 15, 2019 Category: Research Authors: Mike Lauer Tags: blog Open Mike Research integrity Source Type: funding

Novel Technology Tools to Facilitate Research Using Next Generation Patient-derived Cancer Models (U01 Clinical Trial Not Allowed)
Funding Opportunity RFA-CA-19-055 from the NIH Guide for Grants and Contracts. Through this Funding Opportunity Announcement (FOA), the National Cancer Institute (NCI) will support the development of technology, tools that will facilitate, accelerate, and/or enhance research using advanced human-derived next generation cancer models, such as organoids, conditionally reprogrammed cells, and others. The studies proposed under this FOA must focus entirely on the next generation cancer models developed under the auspices of an international consortium with NCI participation, Human Cancer Models Initiative. "Technology to...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 28, 2019 Category: Research Source Type: funding

Characterization of Marmosets as Models of Aging and Age-Related Diseases (U34 Clinical Trial Not Allowed)
Funding Opportunity RFA-AG-20-007 from the NIH Guide for Grants and Contracts. The primary aim of this Funding Opportunity Announcement (FOA) is to facilitate the characterization of the marmoset as a laboratory animal for research on aging and age-related diseases. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 14, 2019 Category: Research Source Type: funding

NCI Research Specialist (Laboratory-based Scientist) Award (R50 Clinical Trial Not Allowed)
Funding Opportunity PAR-19-291 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites grant applications for the Research Specialist Award (R50) in any area of NCI-funded cancer research. This FOA is specifically for laboratory-based scientists. The Research Specialist Award is designed to encourage the development of stable research career opportunities for exceptional scientists who want to continue to pursue research within the context of an existing NCI-funded basic, translational, clinical, or population science cancer research program, but not serve as independent investigat...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 5, 2019 Category: Research Source Type: funding

Postdoctoral Research Associate Training (PRAT) Program (Fi2)
Funding Opportunity PAR-19-286 from the NIH Guide for Grants and Contracts. The NIGMS Postdoctoral Research Associate Training (PRAT) Programs overarching goal is to provide high quality postdoctoral research training in the basic biomedical sciences to a diverse group of postdoctoral fellows in NIH Intramural research laboratories, and to prepare them for leadership positions in biomedical careers. Research projects proposed should focus on areas within the NIGMS mission, which include but are not limited to biological chemistry, biophysics, bioinformatics, cellular and molecular biology, computational biosciences, devel...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 21, 2019 Category: Research Source Type: funding

Infrastructure Development Training Programs for Critical HIV Research at Low-and Middle-Income Country Institutions (G11 Clinical Trials Not Allowed)
Funding Opportunity PAR-19-285 from the NIH Guide for Grants and Contracts. The overall goal of the Fogarty International Center (FIC) HIV Research Training Program is to strengthen the scientific capacity of institutions in low- and middle-income countries (LMICs) to conduct HIV research on the evolving HIV epidemic in their countries. This FOA encourages collaborative applications from U.S. and LMIC institutions to support training to achieve technical, administration and financial management expertise required for one of the six research infrastructure functions considered critical to a successful high quality research...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 14, 2019 Category: Research Source Type: funding

Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models (R43/R44 Clinical Trial Not Allowed)
Funding Opportunity PAR-19-265 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) encourages applications from small business concerns (SBCs) for Small Business Innovation Research (SBIR)projects to develop novel tools and devices to improve handling of laboratory animals, to ease the management of animal facilities, and to enhance experiments which use animal models. The intent is to facilitate the design, implementation, and creation of tools and devices to directly benefit the welfare of research animals, and to advance equipment to improve infrastructure and environmental conditio...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 2, 2019 Category: Research Source Type: funding