Scientists find new 'fat genes' that make you six times more likely to be obese - and up to 10,000 Brits carry them
Researchers at the University of Cambridge also found the genetic quirk was linked with an increased risk of non-alcoholic fatty liver disease and of type 2 diabetes. (Source: the Mail online | Health)
Source: the Mail online | Health - April 4, 2024 Category: Consumer Health News Source Type: news

Monthly News Roundup - March 2024
Rezdiffra Approved as First Drug for Nonalcoholic Fatty Liver Disease (NASH)  In March, the U.S. Food and Drug Administration (FDA) granted accelerated approval to Rezdiffra (resmetirom) for adults with noncirrhotic nonalcoholic... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 31, 2024 Category: Pharmaceuticals Source Type: news

SGLT2 Inhibitors Tied to Better NAFLD Outcomes vs Other Antidiabetic Agents
(MedPage Today) -- In adults with both type 2 diabetes and nonalcoholic fatty liver disease (NAFLD), the use of SGLT2 inhibitors was linked to NAFLD regression and a lower incidence of poor liver-related outcomes, according to a retrospective cohort... (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - February 14, 2024 Category: Primary Care Source Type: news

Two risk factors of dangerous silent condition revealed by medical experts
Unhealthy diets, sedentary lifestyles and obesity are pushing up rates of non-alcoholic fatty liver, but this dangerous silent condition is reversible. Luisa Metcalfe asks the experts what we need to know (Source: Daily Express - Health)
Source: Daily Express - Health - January 8, 2024 Category: Consumer Health News Source Type: news

NAFLD Familial Risk Score Tops FIB-4 Index for Finding Fibrosis NAFLD Familial Risk Score Tops FIB-4 Index for Finding Fibrosis
A new risk model for nonalcoholic fatty liver disease could offer a simpler and more accurate way of predicting advanced fibrosis in first-degree relatives.MDedge News (Source: Medscape FamilyMedicine Headlines)
Source: Medscape FamilyMedicine Headlines - December 8, 2023 Category: Primary Care Tags: Gastroenterology Source Type: news

Ultrasound model identifies NAFLD patients with advanced fibrosis
A model using ultrasonic biomarkers could help physicians identify patients with nonalcoholic fatty liver disease (NAFLD) who have advanced fibrosis, a study presented November 30 at the RSNA 2023 annual meeting found. In his presentation, Katsutoshi Sugimoto, MD, PhD, from Tokyo Medical University in Japan discussed the performance of a model he and colleagues developed, which combines multiparametric ultrasound markers. They found that combining normalized local variance with shear-wave speed improves assessment of advanced liver fibrosis. “The combination…improved the diagnostic performance of identifying [disease...
Source: AuntMinnie.com Headlines - December 6, 2023 Category: Radiology Authors: Amerigo Allegretto Tags: Ultrasound Source Type: news

Prevalence of NAFLD Set to Increase to 34.3 Percent in 2050
MONDAY, Nov. 20, 2023 -- The burden of nonalcoholic fatty liver disease (NAFLD) is predicted to continue increasing, according to a study presented at The Liver Meeting, the annual meeting of the American Association for the Study of Liver... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 20, 2023 Category: Pharmaceuticals Source Type: news

Ultrasound platform effective evaluating hepatic steatosis
Thursday, November 30 | 1:30 p.m.-1:40 p.m. | R6-SSGI19-1 | Room E352Attendees will hear about the potential for ultrasound-derived fat fraction to be an alternative tool for MRI in assessing hepatic steatosis.Yi Dong, MD, from Fudan University in Shanghai, China, will present findings that show how ultrasound-derived fat fraction can detect hepatic steatosis using MRI-derived proton density fat fraction as the reference standard.Several ultrasound platforms now provide quantitative measures of hepatic steatosis. One of these is ultrasound-derived fat fraction, which combines attenuation and backscatter quantification. ...
Source: AuntMinnie.com Headlines - November 14, 2023 Category: Radiology Authors: Amerigo Allegretto Tags: 2023 Ultrasound Preview Source Type: news

MASLD Predicted to Increase by 23% by Middle of the Century
(MedPage Today) -- BOSTON -- A mathematical model predicts that the prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) -- formerly known as nonalcoholic fatty liver disease (NAFLD) -- will substantially increase... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - November 12, 2023 Category: Gastroenterology Source Type: news

Torrent, Zydus in co-marketing pact for liver disease drug Saroglitazar
Torrent Pharmaceuticals and Zydus Lifesciences formed a licensing and supply pact to co-market Saroglitazar Mg, the sole approved treatment for Non-Alcoholic Steato Hepatitis (NASH) and Non-Alcoholic Fatty Liver Disease (NAFLD) in India. Under the agreement, Torrent gains semi-exclusive rights to market as VORXAR while Zydus continues marketing as Lipaglyn and Bilypsa. Licensing fees and milestone payments are part of the pact. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - November 10, 2023 Category: Pharmaceuticals Source Type: news

Lupin, Zydus Lifesciences ink licensing, supply pact for Saroglitazar Mg
Lupin and Zydus Lifesciences entered into a licensing and supply agreement to co-market Saroglitazar Mg, an innovative drug approved by India's DCGI for treating non-alcoholic fatty liver disease and non-alcoholic steatohepatitis. Lupin will have semi-exclusive rights to co-market the product in India under the brand name LINVAS. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - November 3, 2023 Category: Pharmaceuticals Source Type: news

MR proton density fat fraction imaging helps predict liver health
MR proton density fat fraction (PDFF) imaging helps predict liver health, researchers have found.The MRI PDFF measure could improve patient care by giving clinicians a more accurate picture of liver disease, a team led by Tianyi Xia, MD, of Zhongda Hospital School of Medicine, Southeast University, in Nanjing, China. The study results were published October 24 in Radiology."We found … that liver MRI PDFF was a causal mediator between potential risk factors and several liver disease risks," the group wrote.Hepatic steatosis is one of the anatomic characteristics of nonalcoholic fatty liver disease, and it is the "leading ...
Source: AuntMinnie.com Headlines - October 25, 2023 Category: Radiology Authors: Kate Madden Yee Tags: Clinical News MRI Source Type: news

From NAFLD to MASLD: What's in a Name? From NAFLD to MASLD: What's in a Name?
Presentations at the European Association for the Study of Diabetes 2023 Annual Meeting in Hamburg, Germany, stressed the gravity of nonalcoholic fatty liver disease and the reasons for its new name.Medscape Diabetes & Endocrinology (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - October 11, 2023 Category: Endocrinology Tags: Diabetes & Endocrinology Commentary Source Type: news

The Story Behind NAFLD's Rebranding as MASLD The Story Behind NAFLD's Rebranding as MASLD
The international group behind the new terminology worked for 3 years to build a consensus, but convincing their peers to adopt it will require more effort.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 5, 2023 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Early-Onset NAFLD Tied to Higher Cancer Risk Early-Onset NAFLD Tied to Higher Cancer Risk
Earlier age at onset of nonalcoholic fatty liver disease was associated with an increased risk for cancer, mainly digestive and lung cancers, in a large cohort study.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - October 4, 2023 Category: Cancer & Oncology Tags: Gastroenterology News Source Type: news