NAFLD and Clinical Outcomes in CKD NAFLD and Clinical Outcomes in CKD
A new study investigates the potential impact of NAFLD on cardiovascular and other outcomes in patients with CKD.Nephrology Dialysis Transplantation (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 18, 2019 Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news

Bioclinica Launches NAFLD/NASH Clinical Trials Practice
Helps sponsors apply medical imaging in trials to advance development of NAFLD/NASH therapeutics.(PRWeb April 18, 2019)Read the full story at https://www.prweb.com/releases/bioclinica_launches_nafld_nash_clinical_trials_practice/prweb16252099.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - April 18, 2019 Category: Pharmaceuticals Source Type: news

Potential new treatment for diabetes and fatty liver disease
A study, published in theBritish Journal of Pharmacology, indicates a new molecule, which promotes the production of the FGF21 hormone, has anti-diabetic and anti-obesogenic effects that may be useful in developing treatments for non-alcoholic fatty liver disease and diabetes.Science Daily (Source: Society for Endocrinology)
Source: Society for Endocrinology - April 12, 2019 Category: Endocrinology Source Type: news

Experts warn of fatty liver disease 'epidemic' in young people
Study finds substantial numbers of young people at risk of liver cancer, diabetes and heart attacksExperts are warning that high levels of fatty liver disease among young people, caused by being overweight, could signal a potential public health crisis.Non-alcoholic fatty liver disease is fairly common among older adults, detectable in about a quarter of the population. But a study has found that substantial numbers of 24-year-olds are also affected, putting them at risk of serious later health problems, such as liver cancer, type-2 diabetes and heart attacks.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - April 12, 2019 Category: Science Authors: Sarah Boseley Health editor Tags: Obesity UK news Medical research Diets and dieting Health Society Life and style Science Source Type: news

Nonalcoholic Fatty Liver Disease Burden Up Among HIV-Infected
THURSDAY, April 11, 2019 -- Nonalcoholic fatty liver disease (NAFLD) is becoming an increasingly important cause of liver disease (LD) and liver mortality among patients with HIV, according to a study presented at The International Liver Congress... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 11, 2019 Category: Pharmaceuticals Source Type: news

College researchers probe racial disparity in fatty liver disease
(Ohio University) Two top researchers at the Ohio University Heritage College of Osteopathic Medicine are working with two other institutions on a federally funded project to investigate why Hispanics are more prone to develop non-alcoholic fatty liver disease (NAFLD). (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 11, 2019 Category: Infectious Diseases Source Type: news

Causality Between NAFLD and Risk of CVD and Type 2 Diabetes Causality Between NAFLD and Risk of CVD and Type 2 Diabetes
This study explores the evidence for a possible causal relationship between non-alcoholic fatty liver disease and type 2 diabetes or cardiovascular disease.Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 8, 2019 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Shared Disease Mechanisms in NAFLD and Metabolic Syndrome Shared Disease Mechanisms in NAFLD and Metabolic Syndrome
Advancements in our understanding of the interactions between NAFLD and metabolic syndrome-associated disorders could help better define therapeutic targets.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 8, 2019 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

New insights into how fatty liver disease progresses to cancer
(Experimental Biology) The buildup of fat in the liver known as fatty liver disease sometimes leads to hard-to-treat liver cancer. Scientists don't understand why the cancer risk is higher for fatty liver disease caused by excessive alcohol consumption than for non-alcoholic fatty liver disease, which is associated with obesity and type 2 diabetes. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 6, 2019 Category: Cancer & Oncology Source Type: news

Fecal Microbiome Signature Detects Cirrhosis in Nonalcoholic Fatty-Liver Disease Fecal Microbiome Signature Detects Cirrhosis in Nonalcoholic Fatty-Liver Disease
A fecal microbiome signature accurately detects cirrhosis in patients with nonalcoholic fatty-liver disease (NAFLD), researchers report.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 5, 2019 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Metformin for NAFLD and NASH Metformin for NAFLD and NASH
Should metformin be recommended in patients with NAFLD or NASH? Find the evidence-based answer here.American Family Physician (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 5, 2019 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

Blocking platelets: A possible option to prevent fatty liver disease and liver cancer
(German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ)) Blood platelets which interact with liver cells and immune cells play a major role in the development of fatty liver disease, non-alcoholic fatty liver inflammation and liver cancer, scientists from the German Cancer Research Center (DKFZ) in Heidelberg and from Zurich University and University Hospital have now shown in a publication. The researchers have also worked out new approaches for using drugs to keep the development of fatty liver disease in check, thus preventing liver cancer in the long term. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 1, 2019 Category: Cancer & Oncology Source Type: news

Endra Life Sciences touts preliminary TAEUS liver fat analysis study data
Endra Life Sciences today reported preliminary results from the first-in-man feasibility study of its Thermo Acoustic Enhanced Ultrasound System exploring its ability to measure and analyze liver fat. The TAEUS platform is designed to allow for the visualization of human tissue composition, function and temperature at a cheaper cost than computed tomography or magnetic resonance imaging and provided at the point-of-care, the Ann Arbor, Mich.-based company said. Preliminary data came from 25 subjects analyzed with the TAEUS platform as compared with quantitative MRI fat fraction measurements and other indicators including B...
Source: Mass Device - March 29, 2019 Category: Medical Devices Authors: Fink Densford Tags: Clinical Trials Imaging endralifesciences Source Type: news

Liver disease in overweight children linked to subclinical hypothyroidism
Non-alcoholic fatty liver disease in obese Latino children may be linked to subclinical hypothyroidism, according to research presented at the Endocrine Society annual meeting.Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - March 29, 2019 Category: Endocrinology Source Type: news

Movement toward a poop test for liver cirrhosis
(University of California - San Diego) In a study of people with nonalcoholic fatty liver disease and their twins and other close relatives, UC San Diego researchers were able to diagnose liver cirrhosis simply by analyzing a person's stool microbes. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - March 29, 2019 Category: Biology Source Type: news

NAFLD, Osteoporotic Fractures, and Bone Mineral Density NAFLD, Osteoporotic Fractures, and Bone Mineral Density
To what extent does NAFLD affect osteoporosis and bone health?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 27, 2019 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Microbiota May Help Single Out'Lean' NAFLD
(MedPage Today) -- Blood, fecal bacteria composition differed between lean and obese patients with fatty liver disease (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - March 19, 2019 Category: Endocrinology Source Type: news

CKD and Increased Mortality in Patients With NAFLD CKD and Increased Mortality in Patients With NAFLD
This study assessed the association between different stages of chronic kidney disease and mortality in patients with nonalcoholic fatty liver disease.Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 11, 2019 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

A Lifestyle Intervention for Metabolic Syndrome With NAFLD A Lifestyle Intervention for Metabolic Syndrome With NAFLD
This study evaluated the impact of a highly structured lifestyle program for weight loss and metabolic fitness in patients with metabolic syndrome, with and without NAFLD.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 11, 2019 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Predictors of NASH and Fibrosis in Non-obese NAFLD Predictors of NASH and Fibrosis in Non-obese NAFLD
This study aimed to identify risk factors for nonalcoholic steatohepatitis and fibrosis in NAFLD. How do clinical and histological characteristics differ between obese and non-obese patients?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 4, 2019 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Towards a blood test for early-stage liver disease
(EMBO) One in four people in Western and Asian societies develop a build-up of fat in the liver as a result of an unhealthy diet. This disease -- non-alcoholic fatty liver disease (NAFLD) -- causes no symptoms initially but can develop into end-stage liver cirrhosis. A discovery, published today in Molecular Systems Biology, paves the way for a simple blood test to detect early stages of NAFLD, opening up the possibility of preventing the development of liver cirrhosis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 1, 2019 Category: International Medicine & Public Health Source Type: news

Researchers identify potential mechanism to control nonalcoholic fatty liver disease
FINDINGSIn a comprehensive, nine-year-long study in mice, researchers profiled more than 300 liver and plasma lipid species and more than 5,000 liver proteins. The combined data helped researchers to identify new mechanisms that control the metabolism of lipids (molecules that include fat) and to discover a protein that regulates lipids. They found that silencing one particular protein, called PSMD9, is a potential therapeutic strategy to reduce nonalcoholic fatty liver disease.BACKGROUNDNonalcoholic fatty liver disease is the buildup of excess fat in liver cells not caused by alcohol. The disease affects about 25 percent ...
Source: UCLA Newsroom: Health Sciences - February 28, 2019 Category: Universities & Medical Training Source Type: news

Nonalcoholic fatty liver disease, commonly associated with diabetes, increases the risk of heart disease, and liver, colorectal, and breast cancers
(Natural News) In a new study that was published in the Journal of Hepatology, researchers were able to surmise that nonalcoholic fatty liver disease (NAFLD) is not only associated with hepatocellular carcinoma (HCC), but also to cancers that have nothing to do with the liver, such as colorectal and breast cancers. “NAFLD is a very... (Source: NaturalNews.com)
Source: NaturalNews.com - February 21, 2019 Category: Consumer Health News Source Type: news

Antioxidants for Pediatric NAFLD Antioxidants for Pediatric NAFLD
Can a simple phenol of extra virgin olive oil given with vitamin E improve NAFLD in children?Medscape Pediatrics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 20, 2019 Category: Consumer Health News Tags: Pediatrics Article Source Type: news

Liver disease may increase diabetes risk in non-obese patients
Research, published inNutrition,Metabolism and Cardiovascular Diseases, suggests that non-alcoholic fatty liver disease increases diabetes risk in non-obese adults.Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - February 18, 2019 Category: Endocrinology Source Type: news

Reducing NAFLD-Screening Time: Alternatives to Ultrasound Reducing NAFLD-Screening Time: Alternatives to Ultrasound
This study compared eight different scoring methods to determine likelihood of NAFLD, with the aim of excluding patients at low risk prior to ordering an ultrasound scan.Liver International (Source: Medscape Radiology Headlines)
Source: Medscape Radiology Headlines - February 4, 2019 Category: Radiology Tags: Gastroenterology Journal Article Source Type: news

NAFLD in Adolescent Boys Improves With Low Sugar Diet NAFLD in Adolescent Boys Improves With Low Sugar Diet
Adolescent boys on a"low free sugar" diet show significant improvements in nonalcoholic fatty liver disease (NAFLD), according to results from an 8-week randomized clinical trial.Reuters Health Information (Source: Medscape Radiology Headlines)
Source: Medscape Radiology Headlines - January 24, 2019 Category: Radiology Tags: Gastroenterology News Source Type: news

Differential Diagnosis of Lysosomal Acid Lipase Deficiency Differential Diagnosis of Lysosomal Acid Lipase Deficiency
Was this obese 12-year-old boy's abnormal lipid profile and elevated liver enzymes due to NAFLD or something more unusual?Laboratory Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 23, 2019 Category: Consumer Health News Tags: Pathology & Lab Medicine Journal Article Source Type: news

Study shows low-sugar diet effective in boys with nonalcoholic fatty liver disease
(University of California - San Diego) Researchers at University of California San Diego School of Medicine found that a diet low in free sugars (those added to foods and beverages and occurring naturally in fruit juices) resulted in significant improvement in nonalcoholic fatty liver disease (NAFLD) in adolescent boys. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 22, 2019 Category: International Medicine & Public Health Source Type: news

Cardiovascular Risk Factors in NAFLD Cardiovascular Risk Factors in NAFLD
Can histological parameters in NAFLD, including NASH and fibrosis stage, help predict cardiovascular risk?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 14, 2019 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Mixed Results With MRI for Liver Triglycerides in NAFLD
(MedPage Today) -- Proton density fat fraction MRI correlated with steatosis grade; suboptimal for advanced fibrosis (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - January 2, 2019 Category: Endocrinology Source Type: news

The role of PCSK9 in the pathogenesis of non-alcoholic fatty liver disease
(Bentham Science Publishers) Data indicates that high intrahepatic or circulating PCSK9 levels increase muscle and liver lipid storage, adipose energy storage and hepatic fatty acids, as well as triglycerides storage and secretion, thus contributing to the pathogenesis of NAFLD. The findings of animal and human studies, aiming to reduce PCSK9 with inhibitors point towards liver protection from NAFLD through inhibition of PCSK9 expression in the induction of degradation of hepatic HNF1a protein, insulin resistance (IR), and other mechanisms. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 1, 2019 Category: International Medicine & Public Health Source Type: news

Medical News Today: Why green leafy vegetables can protect liver health
Inorganic nitrate, a compound present in celery, spinach, and rocket, may protect against nonalcoholic fatty liver disease, a new study shows. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 20, 2018 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

New research shows how a fatty diet can lead to life-threatening liver disease
(University of Southern California - Health Sciences) A new study by USC scientists provides new insight on how dietary fat and cholesterol drive the development of non-alcoholic steatohepatitis (NASH), a serious form of non-alcoholic fatty liver disease (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 20, 2018 Category: International Medicine & Public Health Source Type: news

NAFLD Is Associated With Decreased Lung Function NAFLD Is Associated With Decreased Lung Function
This large-scale longitudinal study aimed to clarify the association of NAFLD and lung function.Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 17, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

The Asian water plantain is a natural remedy for nonalcoholic fatty liver disease
(Natural News) Nonalcoholic fatty liver disease is not a serious condition in itself, but its complications can be deadly. The extract of Asian water plantains (Alisma orientale) could be a potential treatment for the condition, according to a study in BMC Complementary and Alternative Medicine, as it is able to not only reduce the amount of... (Source: NaturalNews.com)
Source: NaturalNews.com - December 16, 2018 Category: Consumer Health News Source Type: news

Longer Breastfeeding Tied to Lower Risk of NAFLD Longer Breastfeeding Tied to Lower Risk of NAFLD
Mothers who breastfeed for six months or more may have less fat in their livers and a lower risk of liver disease, a U.S. study suggests.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 13, 2018 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Serum Testosterone and NAFLD in Men and Women in the US Serum Testosterone and NAFLD in Men and Women in the US
This study examined the relationship between total serum testosterone levels and non-alcoholic fatty liver disease. Might low levels be a risk factor for NAFLD?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 10, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Increasing the amount of protein in your diet may lower your risk for diabetes
(Natural News) According to a study, which was published in the American Journal of Physiology-Endocrinology and Metabolism, consuming more protein can help reduce the liver’s fat content. Making this change to your diet may even help lower the risk of diabetes in individuals with nonalcoholic fatty liver disease (NAFLD). What is nonalcoholic fatty liver disease (NAFLD)? NAFLD,... (Source: NaturalNews.com)
Source: NaturalNews.com - December 9, 2018 Category: Consumer Health News Source Type: news

Prognostic Value of the FibroTest in Patients With NAFLD Prognostic Value of the FibroTest in Patients With NAFLD
This study validated the prognostic performance of FibroTest for both overall survival and survival without liver-related deaths in patients with NAFLD.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 27, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Study suggests eating more lycopene-rich foods to prevent nonalcoholic fatty liver disease
(Natural News) Lycopene, a compound found in a number of fruits and vegetables, can help address the symptoms of non-alcoholic fatty liver disease (NAFLD), proving just how important these foods are to living a full and healthy life. Excessive fat has far-reaching repercussions on your health. You may be familiar with the role it plays... (Source: NaturalNews.com)
Source: NaturalNews.com - November 27, 2018 Category: Consumer Health News Source Type: news

Omega-3 fatty acids found to control non-alcoholic fatty liver disease
(Natural News) It is a little-known fact that even teetotalers can end up with liver disease. In fact, the most common form of this type of disease in the United States – non-alcoholic fatty liver disease (NAFLD) – affects close to 100 million people and can affect even those who drink little or no alcohol.... (Source: NaturalNews.com)
Source: NaturalNews.com - November 15, 2018 Category: Consumer Health News Source Type: news

UMN researchers discover important connection between cells in the liver
(University of Minnesota Medical School) University of Minnesota Medical School researchers have made a discovery which could lead to a new way of thinking about how disease pathogenesis in the liver is regulated, which is important for understanding the condition nonalcoholic fatty liver disease (NAFLD), which is incredibly common and growing. It is apparent that about 30 percent of Americans and are at risk to advance to more severe conditions such as nonalcoholic steatohepatitis (NASH), cirrhosis, cardiovascular disease, or even liver cancer. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 15, 2018 Category: International Medicine & Public Health Source Type: news

Infants born to obese mothers risk developing liver disease, obesity
(University of Colorado Anschutz Medical Campus) Infant gut microbes altered by their mother's obesity can cause inflammation and other major changes within the baby, increasing the risk of obesity and non-alcoholic fatty liver disease later in life, according to researchers at the University of Colorado Anschutz Medical Campus. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - November 15, 2018 Category: Biology Source Type: news

Novel Thyroid Beta Receptor Agonist Cut LDL-C in NAFLD Patients
(MedPage Today) -- Small phase II study also found reductions in liver fat vs placebo (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - November 13, 2018 Category: Primary Care Source Type: news

Drug-induced Liver Injury in the Context of NAFLD Drug-induced Liver Injury in the Context of NAFLD
This article explores the pathophysiological mechanisms and reciprocity involved in NAFLD and drug-induced steatohepatitis.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 13, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Risks for Most Cancers Higher with NAFLD
(MedPage Today) -- Condition may drive obesity-related cancers (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - November 12, 2018 Category: Endocrinology Source Type: news

Impact of Diabetes on Non-invasive Fibrosis Models in NAFLD Impact of Diabetes on Non-invasive Fibrosis Models in NAFLD
Are non-invasive serum fibrosis models less accurate for diagnosing cirrhosis and predicting future HCC and liver decompensation events in NAFLD patients with diabetes versus those without?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 8, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Recent research suggests that even low exposure to glyphosate can contribute to liver damage
(Natural News) Back in 2015, the American Liver Foundation estimated that at least one in four Americans was living with non-alcoholic fatty liver disease (NAFLD), an illness that can affect even those who drink little or no alcohol. People in their 40s and 50s are most vulnerable, especially those who carry extra weight around their... (Source: NaturalNews.com)
Source: NaturalNews.com - October 29, 2018 Category: Consumer Health News Source Type: news

Clues to the link between obesity and liver cancer-and identification of a new risk group
(Monash University) New research has found a previously overlooked group of obese people may be at risk of developing deadly liver cancer. Most obese individuals who develop liver cancer first develop non-alcoholic fatty liver disease, and then the more severe non-alcoholic steatohepatitis. This can lead to cirrhosis and liver failure. However, this research reveals pathways to the development of liver cancer in obese people that are not reliant on the development of non-alcoholic steatohepatitis or cirrhosis. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 25, 2018 Category: Cancer & Oncology Source Type: news