How high fructose intake may trigger fatty liver disease
A study suggested that consuming high amounts of fructose may promote non-alcoholic fatty liver disease by damaging the intestinal barrier. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - September 15, 2020 Category: Consumer Health News Source Type: news

Researchers find molecular link between liver disease, insulin resistance
Yale researchers have zeroed in on a molecular link between nonalcoholic fatty liver disease and liver insulin resistance in type 2 diabetes. (Source: Yale Science and Health News)
Source: Yale Science and Health News - September 2, 2020 Category: Universities & Medical Training Source Type: news

Menopause may increase risk for non-alcoholic fatty liver disease
Postmenopausal women may be more likely to develop non-alcoholic fatty liver disease due to a reduction in sex hormones, suggests a study published in Endocrinology.News Medical (Source: Society for Endocrinology)
Source: Society for Endocrinology - August 26, 2020 Category: Endocrinology Source Type: news

New insights into mechanism of therapy to reduce liver fat and prevent fibrosis
(Massachusetts General Hospital) A team led by researchers at Massachusetts General Hospital (MGH) has taken an important step forward in the goal of developing a potential treatment for non-alcoholic fatty liver disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 26, 2020 Category: International Medicine & Public Health Source Type: news

TGen review suggests postmenopausal women at risk for nonalcoholic fatty liver disease
(The Translational Genomics Research Institute) NAFLD is the most common cause of liver damage, and can lead to liver cirrhosis and death. It affects nearly 1 in 4 people across the globe. It often is associated with obesity, abnormally high amounts of lipids in the blood, and type 2 diabetes. In the US, the number of NAFLD cases is expected to grow to more than 100 million within the next decade, annually costing an estimated at $292 billion. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 14, 2020 Category: International Medicine & Public Health Source Type: news

NAFLD May Predict Arrhythmia Recurrence Post-AF Ablation NAFLD May Predict Arrhythmia Recurrence Post-AF Ablation
The presence of nonalcoholic fatty liver disease adds a further modifiable target for preablation medical optimization, researchers say.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - August 14, 2020 Category: Cardiology Tags: Cardiology News Source Type: news

Fatty liver disease despite a normal weight
(University of Tsukuba) Researchers from the University of Tsukuba found significant differences in the clinical presentation of non-obese patients with non-alcoholic fatty liver disease (NAFLD) based on their sex and body mass index. They found that non-obese NAFLD patients had lower muscle mass and strength (pre-sarcopenia) compared to obese NAFLD patients. Further, fat accumulation in muscles was more common among women. These findings help us understand the clinical presentation of NAFLD. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 3, 2020 Category: International Medicine & Public Health Source Type: news

NAFLD: It's More Than Just the Fat NAFLD: It's More Than Just the Fat
As a'big club'that everyone could belong to, it's past time to understand NAFLD better.The Curbsiders (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 31, 2020 Category: Consumer Health News Tags: Family Medicine/Primary Care Commentary Source Type: news

Insight on novel genetic approaches to metabolic liver diseases
(Wayne State University - Office of the Vice President for Research) Faculty from Wayne State University's Eugene Applebaum College of Pharmacy and Health Sciences are leading a team of researchers to understand the causal relationships between diabetes, obesity and nonalcoholic fatty liver disease in hopes of developing a treatment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 31, 2020 Category: International Medicine & Public Health Source Type: news

Women Suffer Less NAFLD but More Advanced Fibrosis Women Suffer Less NAFLD but More Advanced Fibrosis
Given the higher risk of advanced fibrosis among women compared to men with NAFLD, it is plausible that cirrhosis and its complications may occur with greater frequency among women than in men.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - July 16, 2020 Category: Gastroenterology Tags: Ob/Gyn & Women ' s Health News Source Type: news

Limp handshake? You may be at risk of a potentially fatal liver disease
While social distancing means it's currently barred, new research has revealed that a limp handshake or a weak grip could be an early warning sign of non-alcoholic fatty liver disease. (Source: the Mail online | Health)
Source: the Mail online | Health - July 14, 2020 Category: Consumer Health News Source Type: news

Researchers find promising therapy to fight epidemic of liver disease
(University of Colorado Anschutz Medical Campus) In an effort to combat a growing worldwide epidemic of Nonalcoholic Fatty Liver Disease (NAFLD), scientists have discovered a new target and a new therapy that has shown promising results in preclinical mouse models, according to researchers at the University of Colorado Anschutz Medical Campus. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 8, 2020 Category: Biology Source Type: news

U of SC: How non-alcoholic fatty liver disease causes Alzheimer's-like neuroinflammation
(University of South Carolina) Research from UofSC associate professor Saurabh Chatterjee's laboratory in Environmental Health Sciences at the Arnold School of Public Health has revealed the cause behind the previously established link between non-alcoholic fatty liver disease and neurological problems. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 6, 2020 Category: International Medicine & Public Health Source Type: news

Tamoxifen-related NAFLD: Prevalence, Incidence, Risk Factors Tamoxifen-related NAFLD: Prevalence, Incidence, Risk Factors
How common is the development of fatty liver after tamoxifen treatment in breast cancer patients, and what are the associated risk factors?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 3, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Universal gut microbiome-derived signature predicts cirrhosis
(University of California - San Diego) UC San Diego School of Medicine researchers report that stool microbiomes of NAFLD patients are distinct enough to potentially be used to accurately predict which persons with NAFLD are at greatest risk for having cirrhosis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 30, 2020 Category: International Medicine & Public Health Source Type: news

Curb the symptoms of non-alcoholic fatty liver disease by adopting a Mediterranean diet
(Natural News) Multiple studies have found that eating more fish and plant-based foods like fruits, vegetables and whole grains — typical components of the Mediterranean diet — contribute to good health even in old age. According to Harvard Medical School researchers, people who stick to a Mediterranean diet have a 46 percent higher chance of healthy... (Source: NaturalNews.com)
Source: NaturalNews.com - June 26, 2020 Category: Consumer Health News Source Type: news

NAFLD Progression Rates to Cirrhosis, Decompensation, Mortality NAFLD Progression Rates to Cirrhosis, Decompensation, Mortality
This study aimed to elucidate the natural history of NAFLD/NASH by evaluating the impact of liver disease severity and comorbid health conditions on risk of mortality and risk of disease progression.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 22, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Novel antisense drug shows promise in slowing fatty liver disease
(University of California - San Diego) A first-in-class clinical trial suggests a novel treatment measurably slowed progression of non-alcoholic fatty liver disease to its more progressive and deadly form. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 16, 2020 Category: International Medicine & Public Health Source Type: news

Risk for Maternal, Neonatal Complications Increased With NAFLD
TUESDAY, June 9, 2020 -- Women with non-alcoholic fatty liver disease (NAFLD) have increased risks for maternal and neonatal complications, according to a study published online June 9 in the Journal of Hepatology. Monika Sarkar, M.D., from the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 9, 2020 Category: Pharmaceuticals Source Type: news

Fecal transplants show promise as treatment for non-alcoholic fatty liver disease
(Lawson Health Research Institute) A new study from Lawson Health Research Institute and Western University suggests that fecal transplants could be used as a treatment for non-alcoholic fatty liver disease (NAFLD). The randomized controlled trial published in The American Journal of Gastroenterology found that fecal transplants in patients with NAFLD result in a reduction in how easily pathogens and other unwanted molecules pass through the human gut and into circulation, known as intestinal permeability. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 9, 2020 Category: International Medicine & Public Health Source Type: news

Mediterranean diet found to ameliorate symptoms of nonalcoholic fatty liver disease
In this study, Greek researchers investigated the effects of the Mediterranean diet (MedDiet) on the clinical, biochemical and inflammatory profile of patients with simple liver steatosis. Their results were published in the Journal of Medicinal Food. Diet is a modifiable key factor and target for the prevention or management of non-alcoholic fatty liver disease (NAFLD).... (Source: NaturalNews.com)
Source: NaturalNews.com - June 2, 2020 Category: Consumer Health News Source Type: news

Modified Parkinson's drug shows potential in treating nonalcoholic fatty liver disease
(GIST(Gwangju Institute of Science and Technology)) Nonalcoholic fatty liver disease (NAFLD) severely impairs the quality of life in patients and often leads to various liver complications. Recently, scientists at Gwangju Institute of Science and Technology designed a novel compound that can potentially treat NAFLD by targeting peripheral serotonin, which regulates lipid metabolism in the liver. They achieved this by structurally modifying an existing neurological drug such that it targets peripheral serotonin by minimizing brain penetration. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - May 28, 2020 Category: Biology Source Type: news

More Severe COVID-19 in Patients With Liver Fibrosis More Severe COVID-19 in Patients With Liver Fibrosis
Patients with non-alcoholic fatty liver disease (NAFLD) and increased liver-fibrosis scores experience more severe illness from COVID-19, according to a study of Chinese patients.Reuters Health Information (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - May 26, 2020 Category: Intensive Care Tags: Gastroenterology News Source Type: news

High Rate of Fatty Liver Disease Found in 9/11 Responders High Rate of Fatty Liver Disease Found in 9/11 Responders
The risk for nonalcoholic fatty liver disease appears to be elevated in 9/11 first responders in New York City, new research shows.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 22, 2020 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Navigating nonalcoholic fatty liver disease (NAFLD)
(American Gastroenterological Association) Gastroenterology, the official journal of the American Gastroenterological Association (AGA), has released a special issue providing clinicians and researchers an up-to-date resource on the risk factors, natural history, diagnosis and treatment of nonalcoholic fatty liver disease (NAFLD). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 19, 2020 Category: International Medicine & Public Health Source Type: news

BioIVT introduces high-purity Kupffer cells to support drug discovery and development for liver diseases and help predict adverse drug reactions
(Rana Healthcare Solutions LLC) BioIVT is adding high-purity Kupffer cells to its portfolio of human primary hepatic cells to support drug discovery and development for liver diseases and help predict adverse drug reactions. Kupffer cells perform a scavenger role in the liver, removing small particles, senescent cells and cell debris. They also play an important role in the immune response to liver pathogens. Dysregulation of this response contributes to liver diseases such as NAFLD, NASH, and liver fibrosis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 11, 2020 Category: International Medicine & Public Health Source Type: news

High Clinical Burden Associated With Nonalcoholic Fatty Liver Disease
WEDNESDAY, May 6, 2020 -- The clinical burden associated with nonalcoholic fatty liver disease (NAFLD) is high, according to a study published online May 5 in Alimentary Pharmacology and Therapeutics. Rohit Loomba, M.D., from the University of... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 6, 2020 Category: Pharmaceuticals Source Type: news

Light-to-Moderate Alcohol Consumption Tied to Increased Type 2 Diabetes Risk With NAFLD Light-to-Moderate Alcohol Consumption Tied to Increased Type 2 Diabetes Risk With NAFLD
People with nonalcoholic fatty liver disease are at increased risk of developing type 2 diabetes when they consume light-to-moderate amounts of alcohol than when they abstain from drinking, a Chinese study suggests.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 1, 2020 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Diet Quality and Its Association With NAFLD and Mortality Diet Quality and Its Association With NAFLD and Mortality
This study investigated the impact of diet on non-alcoholic fatty liver disease. Can a high quality diet lower risk of cancer-related and all-cause mortality?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 29, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Liver Stiffness Measurement, Survival, Complications in NAFLD Liver Stiffness Measurement, Survival, Complications in NAFLD
How accurate is liver stiffness measurement for predicting overall survival and liver, cardiovascular and oncologic complications in NAFLD?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 16, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Sugar, Fat, Alcohol … What’s Worse for the Liver?
This webinar will investigate the increasing mortality rates of liver disease in the UK associated with obesity and the excess consumption of alcohol. It will give an overview of non-alcoholic fatty liver disease (NAFLD), which is now the most common  of liver disease affecting an estimated 25-30% of adults and 10% of children in the UK and worldwide. Both NAFLD and alcohol-related fatty liver can progress to severe liver disease including fibrosis, cirrhosis and hepatocellular carcinoma. The roles of genetics, obesity and dietary patterns i n the development and progression of liver disease will be dis...
Source: The Nutrition Society - April 9, 2020 Category: Nutrition Authors: Jade Mitchell Source Type: news

Advanced Fibrosis and Incident CVD in Patients With NAFLD Advanced Fibrosis and Incident CVD in Patients With NAFLD
This study aimed to determine the factors associated with incident cardiovascular events in patients with NAFLD.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 8, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Potential early biomarker to track development of non-alcoholic fatty liver disease
(Joslin Diabetes Center) Research from Rohit N. Kulkarni's lab at Joslin Diabetes Center has uncovered a biomarker in humans tied to the development of Non-Alcoholic Fatty Liver Disease that might help doctors detect early stages of the disease. The researchers also determined that this biomarker, a protein known as 'neuronal regeneration related protein' (or NREP), plays a significant role in the regulation of a pathway that is currently being reviewed in clinical trials as a treatment option for the disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 6, 2020 Category: International Medicine & Public Health Source Type: news

PCOS Is Associated With NASH Severity and Advanced Fibrosis PCOS Is Associated With NASH Severity and Advanced Fibrosis
Does polycystic ovary syndrome influence severity of non-alcoholic fatty liver disease and risk of advanced fibrosis?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 10, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

AI unlocks screening potential of body CT exams
Artificial intelligence (AI)-based assessment of body composition biomarkers...Read more on AuntMinnie.comRelated Reading: From lab to clinic: How AI can help AI enables screening of fracture risk from CT scans AI spots heart disease on CT lung screening exams AI accurately detects vertebral fractures on CT Can AI screen for nonalcoholic fatty liver disease? (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - March 6, 2020 Category: Radiology Source Type: news

Zydus Cadila gets DCGI nod for world's first drug to treat liver disease
The Ahmedabad-based company said the approved product is the first ever drug anywhere in the world for treatment of Non-Cirrhotic Non-Alcoholic SteatoHepatitis (NASH) which is a progressive disease of the liver. The condition starts with fat accumulation in the liver known as non-alcoholic fatty liver disease and progress to cirrhosis and liver failure. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - March 5, 2020 Category: Pharmaceuticals Source Type: news

Researchers help restore hormonal balance disrupted in metabolic diseases
A new Yale study describes the molecular mechanisms that trigger metabolic imbalance that leads to diabetes and non-alcoholic fatty liver disease. (Source: Yale Science and Health News)
Source: Yale Science and Health News - March 4, 2020 Category: Universities & Medical Training Source Type: news

FDA grants Breakthrough Device Designation for Roche's Elecsys GALAD score to support earlier diagnosis of hepatocellular carcinoma
Basel, 4 March 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Device Designation to the Elecsys ® GALAD score.* This algorithmic score combines gender and age with the biomarker results of the Elecsys AFP, AFP-L3 and PIVKA-II and is intended to aid diagnosis of early stage hepatocellular carcinoma (HCC). Dr. Amit Singal, Medical Director of the Liver Tumor Program   and Clinical Chief of Pathology at UT Southwestern Medical Center in Dallas, USA, stated, " HCC is the fourth leading cause of cancer-related death worldwide, wit...
Source: Roche Investor Update - March 4, 2020 Category: Pharmaceuticals Source Type: news

NAFLD and Risk of New-onset AF in Healthy Adults NAFLD and Risk of New-onset AF in Healthy Adults
This study investigated whether NAFLD is independently associated with increased risk for new-onset AF in a healthy population-based cohort.Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 3, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Heart Failure Risk With NAFLD May Be Explained by Obesity Heart Failure Risk With NAFLD May Be Explained by Obesity
The excess weight that causes fatty liver disease also raises a person's risk for heart failure, a recent study suggests.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 28, 2020 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

A compound in five-flavor fruit can protect the liver, says research
(Natural News) Non-alcoholic fatty liver disease (NAFLD) is the name given to a common disorder in which the livers of people who drink little to no alcohol accumulate excess fat. While largely harmless in its early stages, NAFLD can become a serious health problem if it worsens. Therefore, the prevention and treatment of NAFLD is... (Source: NaturalNews.com)
Source: NaturalNews.com - February 28, 2020 Category: Consumer Health News Source Type: news

Applying Guidelines for NAFLD in HIV-Monoinfected Patients Applying Guidelines for NAFLD in HIV-Monoinfected Patients
Current guidelines recommend the use of a diagnostic algorithm to screen for NAFLD. Could these guidelines also be applied to HIV-monoinfected patients?HIV Medicine (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - February 12, 2020 Category: Infectious Diseases Tags: HIV/AIDS Journal Article Source Type: news

Metabolic Syndrome, But Not NAFLD, Increases 10-year Mortality Metabolic Syndrome, But Not NAFLD, Increases 10-year Mortality
This study compared 10-year mortality among those with and without NAFLD in an urban South Asia cohort. What factors were associated with early risk of death?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 11, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Many Patients With NAFLD Should Be Screened for Liver Cancer, Experts Say Many Patients With NAFLD Should Be Screened for Liver Cancer, Experts Say
Screening and surveillance for hepatocellular carcinoma (HCC) is important in many patients with nonalcoholic fatty liver disease (NAFLD), according to an expert panel of the American Gastroenterological Association (AGA).Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - February 11, 2020 Category: Pathology Tags: Gastroenterology News Source Type: news

Modifiable Risk Factors and Long-term Outcomes of NAFLD Modifiable Risk Factors and Long-term Outcomes of NAFLD
Cardiovascular disease is a leading cause of mortality in patients with non-alcoholic fatty liver disease. Can modifying CV risk factors and health behaviors improve outcomes?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 5, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

FibrometerV2G vs. Enhanced Liver Fibrosis Score in NAFLD FibrometerV2G vs. Enhanced Liver Fibrosis Score in NAFLD
Do the Enhanced Liver Fibrosis score and the FibroMeterV2G have equal accuracy in the non-invasive diagnosis of advanced liver fibrosis in patients with NAFLD?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 6, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

NAFLD in Nonobese Subjects of African Origin NAFLD in Nonobese Subjects of African Origin
How do the metabolic features of nonobese NAFLD among persons of African origin differ from those in other populations?Journal of the Endocrine Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 19, 2019 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Researchers look at the ability of cordyceps to "burn" fat in the liver
(Natural News) Extracts from the medicinal mushroom Cordyceps militaris can potentially be used to prevent — even reverse — nonalcoholic fatty liver disease (NAFLD), one of the most prevalent forms of liver disease among American adults. In a study published in the Journal of Medicinal Food, researchers from South Korea investigated whether C. militaris can regulate lipogenesis in the... (Source: NaturalNews.com)
Source: NaturalNews.com - December 12, 2019 Category: Consumer Health News Source Type: news

Taming chronic inflammation may reduce illness, save lives
Scientists from 22 institutions, including UCLA, are recommending early diagnosis, prevention and treatment of severe chronic inflammation to reduce the risk of chronic disease and death worldwide.The group of international experts, which also includes scientists from the National Institutes of Health, Stanford University, Harvard Medical School, Columbia University Medical Center and University College London, point to inflammation-related diseases as the cause of 50 percent of all deaths worldwide.Inflammation is a naturally occurring response by the body ’s immune system that helps fight illness and infection. Whe...
Source: UCLA Newsroom: Health Sciences - December 5, 2019 Category: Universities & Medical Training Source Type: news

Zydus Cadila files NDA for Saroglitazar Magnesium
NASH is a progressive disease of the liver and a significant unmet medical need. There are currently no treatments available for the treatment of NASH. aroglitazar Mg has previously demonstrated improvement in both liver enzymes along with favorable effects on lipid and glycemic indices in patients with nonalcoholic fatty liver disease in Phase II clinical trials. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - December 5, 2019 Category: Pharmaceuticals Source Type: news