MR proton density fat fraction imaging helps predict liver health

MR proton density fat fraction (PDFF) imaging helps predict liver health, researchers have found.The MRI PDFF measure could improve patient care by giving clinicians a more accurate picture of liver disease, a team led by Tianyi Xia, MD, of Zhongda Hospital School of Medicine, Southeast University, in Nanjing, China. The study results were published October 24 in Radiology."We found … that liver MRI PDFF was a causal mediator between potential risk factors and several liver disease risks," the group wrote.Hepatic steatosis is one of the anatomic characteristics of nonalcoholic fatty liver disease, and it is the "leading cause of chronic liver disease globally," the authors explained. There are a variety of ways to assess liver fat content, but MRI PDFF has shown high diagnostic precision."Liver MRI PDFF provides valuable information regarding triglyceride accumulation within hepatic tissue," the authors wrote. "Importantly, reductions in MRI PDFF have shown a strong correlation with improvements in hepatic steatosis and other histologic features like fibrosis, ballooning degeneration, and lobular inflammation."Research on the relationship between liver MRI PDFF and liver disease is lacking, according to Xia and colleagues. The team conducted a study to investigate any connection between the two, using data from U.K. Biobank (a U.K. biomedical database that consists of genetic and health information from 500,000 participants) and FinnGen (a Finnish biobank, also with 500,000...

Source: AuntMinnie.com Headlines - October 25, 2023 Category: Radiology Authors: Kate Madden Yee Tags: Clinical News MRI Source Type: news