Optimal trough concentration of teicoplanin for the treatment of methicillinresistant Staphylococcus aureus infection: A systematic review and metaanalysis
What is known and objective: It has been recommended that the trough concentration (Cmin) of teicoplanin should be maintained at ≥20 μg/ml for difficult‐to‐treat complicated infections caused by methicillin‐resistant Staphylococcus aureus (MRSA). Conversely, Cmin of teicoplanin of at least 10 μg/ml is required for non‐complicated MRSA infections. Considering the low incidence of nephrotoxicity for teicoplanin, Cmi n = 15–30 μg/ml has been suggested for most MRSA infections. Thus, we assessed the clinical efficacy and adverse effects of teicoplanin at this target Cmin. Methods: We searched electron...
Source: Current Awareness Service for Health (CASH) - June 17, 2021 Category: Consumer Health News Source Type: news

Testicular cancer: Improved treatment and prognosis
(Inselspital, Bern University Hospital) An international research consortium, in which Inselspital, Bern University Hospital and the University of Bern participated, has re-assessed and updated the previous classification of metastatic testicular cancer in a comprehensive study. New indicators and a much broader database enabled a more precise classification and more targeted treatments of patients. In addition, the new data show that the prognosis for patients with metastatic testicular cancer has improved significantly over the past twenty years. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 17, 2021 Category: International Medicine & Public Health Source Type: news

Fish nutrition database to help combat malnutrition across the globe
(Lancaster University) A treasure trove of vital nutritional data about fish species is being made freely available and accessible globally -- plugging a knowledge gap that will bolster efforts to tackle malnutrition across the world. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 17, 2021 Category: Biology Source Type: news

Founder of Cochrane Skin, Professor Hywel Williams, awarded the Order of the British Empire
Professor Hywel Williams has been awarded anOrder of the British Empire (OBE). He has received the award for services to the national Covid-19 research response and his lifelong research into skin diseases.Professor Williams was a founding member of theCochrane Skin group in 1997 and was the Co-ordinating Editor for 21 years. He is a Professor of Dermato-Epidemiology and Co-Director of the Centre of Evidence-Based Dermatology in the School of Medicine at theUniversity of Nottingham, where Cochrane Skin is based.In his role as Director of the NIHR Health Technology Assessment Programme Director and more recently as NIHR Sci...
Source: Cochrane News and Events - June 16, 2021 Category: Information Technology Authors: Muriah Umoquit Source Type: news

Survival among adults with early-onset colorectal cancer
(JAMA Network) Survival among people with early-onset (diagnosed before age 50) colorectal cancer compared with later-onset colorectal cancer (diagnosed at ages 51 through 55) was compared using data from the National Cancer Database. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 16, 2021 Category: Cancer & Oncology Source Type: news

New version of PGAP available now!
We are happy to announce that a new version of PGAP is available. This version will annotate 20 to 25% more genes with symbols (e.g. recA) on the assembled genomes of key species, compared to previous versions. You will observe an increase in symbols when you annotate the genomes of Escherichia coli, Campylobacter jejuni and … Continue reading New version of PGAP available now! → (Source: NCBI Insights)
Source: NCBI Insights - June 15, 2021 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New NCBI Prokaryotic Genome Annotation Pipeline (PGAP) Source Type: news

Indications for 3-D diagnostics and navigation in dental implantology with the focus on radiation exposure: a systematic review
ConclusionThe guidance technique used for implant placement should be decided on an individual basis. With the increasing availability of three-dimensional imaging, there should also be an increase in awareness of radiation exposure. (Source: Dental Technology Blog)
Source: Dental Technology Blog - June 15, 2021 Category: Dentistry Source Type: news

Whether Covid came from a leak or not, it ’s time to talk about lab safety | Gregory D Koblentz and Filippa Lentzos
We studied biosecurity at the world ’s most sophisticated laboratories, and found their policies often left much to be desiredDr Gregory D Koblentz is an associate professor at George Mason University, and Dr Filippa Lentzos is senior lecturer in science and international security at King ’s College LondonThe debate on the origins of the Covid-19 pandemic has recently focused on the potential for the Sars-CoV-2 virus to have escaped from theWuhan Institute of Virology, located in the Chinese city of Wuhan, the centre of the pandemic. This institute houses a maximum containment laboratory, more commonly known as...
Source: Guardian Unlimited Science - June 15, 2021 Category: Science Authors: Gregory D Koblentz and Filippa Lentzos Tags: Microbiology Coronavirus Infectious diseases Science World news Source Type: news

Understanding and mitigating user biases in online information searching
(University of Oklahoma) When searching for information online, the results can vary widely from person to person. Jiqun Liu, an assistant professor in the School of Library and Information Studies in the University of Oklahoma's College of Arts and Sciences, wants to improve the quality of online search results that accounts for users' biases and returns more balanced and useful results. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 15, 2021 Category: International Medicine & Public Health Source Type: news

Knowledge discovery in research on domestic violence: an overview of the last fifty years - Basilio MP, Pereira V, de Oliveira MWCM, da Costa Neto AF, Moraes OCR, Siqueira SCB.
PURPOSE The database of the Web of Science (WoS) was searched for publications from January 1945-May 7, 2020 on the topic of domestic violence in titles, abstracts and keywords. The references were analyzed using the R bibliometrix package, and abstracts w... (Source: SafetyLit)
Source: SafetyLit - June 14, 2021 Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news

Lotka's law and pattern of author productivity in the field of brain concussion research: a scientometric analysis - Roselin Jahina S, Sadik Batcha M, Ahmad M.
The present study deals a scientometric analysis of 8486 bibliometric publications retrieved from the Web of Science database during the period 2008 to 2017. Data is collected and analyzed using Bibexcel software. The study focuses on various aspect of the... (Source: SafetyLit)
Source: SafetyLit - June 14, 2021 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Letter: A scoping review of registered clinical studies on mild traumatic brain injury and concussion (2000-2019) - Ganau L, Ligarotti GKI, Prisco L, Ganau M.
We commend Furlan et al1 on their excellent scoping review assessing clinical trials on mild traumatic brain injury (mTBI) and concussion listed on the database ClinicalTrials.gov. Their study demonstrated that out of 320 registered trials, 73.1% did not p... (Source: SafetyLit)
Source: SafetyLit - June 14, 2021 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Remembering Dr. Murray Enkin
Dr. Murrary  Enkin, whos work contributed to the creation of Cochrane, passed away on 6 June 2021. An obstetrics pioneer and prominent influencer in the early days of the formation of Cochrane, Dr. Murray Enkin was instrumental in developing evidence-based perinatal clinical trials and systematic reviews, challenging many common interventions not supported by research evidence. He, along with his latewife, Eleanor, also strongly advocated for family-centred maternity care such as the presence of fathers during childbirth and non-labour room deliveries.Dr. Enkin, who passed away on 6 June 2021,  gra...
Source: Cochrane News and Events - June 14, 2021 Category: Information Technology Authors: Muriah Umoquit Source Type: news

Remembering Dr Murray Enkin
Dr Murray  Enkin, whose work contributed to the creation of Cochrane, died on 6 June 2021. An obstetrics pioneer and prominent influencer in the early days of the formation of Cochrane, Dr Murray Enkin was instrumental in developing evidence-based perinatal clinical trials and systematic reviews, challenging many common interventions not supported by research evidence. He, along with his late wife, Eleanor, also strongly advocated for family-centred maternity care such as the presence of fathers during childbirth and non-labour room deliveries.Dr Enkin, who died on 6 June 2021,  graduated from medical s...
Source: Cochrane News and Events - June 14, 2021 Category: Information Technology Authors: Muriah Umoquit Source Type: news

Councils need a bold new vision to fund and deliver essential services
The perilous state of local government finances and the future of the sector provoked passionate discussion during the special local government conference. Angela Waller, speaking for the executive, referenced UNISON research that calculated that, in 2020, councils faced a combined funding shortfall of £10 billion. To put the figure into context, Ms Waller said the amount local government lost over 10 years of austerity was 15 billion. “So, 10 billion for just one year is huge.” The impact of a decade of austerity, combined with the effect COVID-19 has had on councils and schools’ costs, raised ques...
Source: UNISON Health care news - June 14, 2021 Category: UK Health Authors: Martin Cullen Tags: Article News local government local government conference 2021 Source Type: news

Anti-Vaccine Activists Use A Federal Database To Spread Fear About COVID Vaccines
The system is designed to provide early warning of what might or might not be actual side-effects. But anti-vaccine groups are bending the data to their own ends.(Image credit: Matt Slocum/AP) (Source: NPR Health and Science)
Source: NPR Health and Science - June 14, 2021 Category: Consumer Health News Authors: Geoff Brumfiel Source Type: news

Anti-Vaccine Activists Use A Federal Database To Spread Fear About COVID Vaccines
(Source: Reuters: Health)
Source: Reuters: Health - June 14, 2021 Category: Consumer Health News Source Type: news

Luxembourg and Frontiers strike national Open Access publishing agreement
(Frontiers) Luxembourg's research community has strengthened its commitment to Open Access through a new national publishing agreement, announced this week. The Biblioth è que Nationale du Luxembourg, the country's national library, and the open access publisher Frontiers have reached a three-year publishing deal that will run until February 2024. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 14, 2021 Category: International Medicine & Public Health Source Type: news

Dacrocystitis in a Teenager?
Discussion Tears are produced in the lacrimal gland which resides in the upper outer quadrant of the eye. The tears flow across the eye medially and are collected in the superior and inferior puncta which drain into their respective canaliculi, and these drain into a common canaliculus. Tears then pass through the valve of Rosenmuler into the lacrimal sac where they are collected. Tears then pass through the nasolacrimal duct, through the distal valve of Hasner and into the nasal cavity. Vascular connections are extensive in this anatomic area and veins do not have valves. Therefore infections can spread easily through dir...
Source: PediatricEducation.org - June 14, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

30,000 Micronesian corals to be cataloged online by University of Guam
(University of Guam) A biorepository of Micronesian marine specimens at the University of Guam Marine Laboratory is welcoming its largest addition yet -- a private collection of around 30,000 coral specimens. They will be cataloged in the coming years to the GECCO Biorepository's online database. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 13, 2021 Category: Biology Source Type: news

Janssen Announces Results from Phase 3 MAIA Study Showing Significant Overall Survival Benefits for Treatment with DARZALEX ® (daratumumab) in Patients with Newly Diagnosed Multiple Myeloma Who are Transplant Ineligible
Raritan, N.J., June 12, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced overall survival (OS) results from the Phase 3 MAIA (NCT02252172) study showing the addition of DARZALEX® (daratumumab) to lenalidomide and dexamethasone (D-Rd) resulted in a statistically significant survival benefit over lenalidomide and dexamethasone (Rd) alone in patients with newly diagnosed multiple myeloma (NDMM) who were ineligible for autologous stem cell transplant (ASCT) and were treated to progression.[1] These data were featured in the European Hematology Association (EHA) 2021 Virtual Press Briefin...
Source: Johnson and Johnson - June 12, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

‘A Year Full of Emotions.’ What Kids Learned From the COVID-19 Pandemic
Too many young generations have been shaped by the global crises they faced—Depression-era poverty, Cold War nuclear fears. Add to them the COVID generation. The virus itself may typically go easier on kids than it does adults, but the mind of a child is another thing. It’s dependent on certainty, safety, the comfort of routine. Take all of that away—shutter schools, keep grandparents at a distance, cancel summer camps—and kids suffer. But as the following lightly-edited stories from young people show, they also grow and learn, gain maturity and wisdom. The virus has been tough; plenty of kids, it t...
Source: TIME: Health - June 12, 2021 Category: Consumer Health News Authors: Jeffrey Kluger and Allison Singer Tags: Uncategorized COVID-19 Source Type: news

Structure viewer iCn3D version 3 featuring analysis of 3D structures!
The NCBI structure viewer iCn3D version 3 is now available on the NCBI web site and from GitHub. Analysis of 3D Structures You can use the current version with the icn3d package at npm to write scripts to call functions in iCn3D. For example, this script on GitHub can calculate the change in interactions due to … Continue reading Structure viewer iCn3D version 3 featuring analysis of 3D structures! → (Source: NCBI Insights)
Source: NCBI Insights - June 11, 2021 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New iCn3D NCBI Structure SARS-CoV-2 Source Type: news

Automate your workflow with the ClinVar Submission API
ClinVar and our scientific and patient-care community rely on your submissions. With our new Application Programming Interface (API) for submissions, we’ve made it even easier for you to provide us with your most up-to-date classification of variants. The new RESTful API allows you to automate your submission workflow so that you can submit new records … Continue reading Automate your workflow with the ClinVar Submission API → (Source: NCBI Insights)
Source: NCBI Insights - June 11, 2021 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New API ClinVar Source Type: news

What We Learned About Genetic Sequencing During COVID-19 Could Revolutionize Public Health
You don’t want to be a virus in Dr. David Ho’s lab. Pretty much every day since the COVID-19 pandemic began, Ho and his team have done nothing but find ways to stress SARS-CoV-2, the virus that causes the disease. His goal: pressure the virus relentlessly enough that it mutates to survive, so drug developers can understand how the virus might respond to new treatments. As a virologist with decades of experience learning about another obstinate virus, HIV, Ho knows just how to apply that mutation-generating stress, whether by starving the virus, bathing it in antibodies that disrupt its ability to infect cells, ...
Source: TIME: Health - June 11, 2021 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 feature Genetics Magazine Source Type: news

Changes in suicide mortality trends in Chile, 1997-2018 - Vidal C, Faunes C, Toro Huerta C, Ruiz-Tagle C, Hoffmeister L.
Using information from the mortality database at Chile's Department of Statistics and Health Information (Ministry of Health), an ecological time-series study was conducted to determine changing trends in suicide rates by sex and age group in Chile from 19... (Source: SafetyLit)
Source: SafetyLit - June 11, 2021 Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news

NLM Technical Bulletin, May-Jun 2021, PMC Labs is here. Let us know what you think!
The National Library of Medicine (NLM) is updating PubMed Central (PMC) to a give you a more modern and easier to use site and we want your feedback. The first phase of this work is now on PMC Labs for you to explore and provide feedback. In the first phase we have focused on modernizing PMC's platform to create a more stable and easy-to-update environment. This also includes some initial changes to the homepage (see Figure 1), site organization, and article pages (see Figure 2). Many of the updates you see on the Labs site create a similar look and feel for PMC and PubMed, reorganizing documentation to highlight the most ...
Source: NLM Technical Bulletin - June 10, 2021 Category: Databases & Libraries Source Type: news

Analysis of child deaths in England shows importance of care for premature and young babies
Actions to reduce the number of babies born before 37 weeks ’ gestation and improve their outcomes are among the recommendations made by the University of Bristol National Child Mortality Database (NCMD) team, who carried out national analysis of child deaths in England. This is one of the findings, published today [10 June] in NCMD ’ s second annual report, which aims to learn lessons from all child deaths in order to reduce the number of children who die in the future. (Source: University of Bristol news)
Source: University of Bristol news - June 10, 2021 Category: Universities & Medical Training Tags: Health, Research; Faculty of Health Sciences, Faculty of Health Sciences, Bristol Medical School; Press Release Source Type: news

NLM Technical Bulletin, May-Jun 2021, New CORE Problem List Subset of SNOMED CT Available for Download
The National Library of Medicine (NLM) is pleased to announce a new Clinical Observations Recordings and Encoding  (CORE) Problem List Subset of SNOMED CT is now available for download by UMLS Licensees. (Source: NLM Technical Bulletin)
Source: NLM Technical Bulletin - June 9, 2021 Category: Databases & Libraries Source Type: news

Impact of the timeliness of antibiotic therapy on the outcome of patients with sepsis and septic shock
Conclusions: While two-thirds of sepsis studies reported an association between early administration of antibiotic therapy and patient outcome, the time-to-antibitiocs metrics varied significantly across studies and no robust time thresholds emerged. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - June 9, 2021 Category: Consumer Health News Source Type: news

Epidemiology of pediatric school-associated ocular injuries from 2000 to 2019 - Patel P, Uppuluri A, Zarbin M, Bhagat N.
[The publisher has not provided an abstract for this article.] Data availability statement Consumer Product Safety Commission. National Electronic Injury Surveillance System 2000-2019 on NEISS Online Database, released April 2020. Generated at https:... (Source: SafetyLit)
Source: SafetyLit - June 9, 2021 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

An explainable machine learning algorithm for risk factor analysis of in-hospital mortality in sepsis survivors with ICU readmission
Background and Objective: Patients who survive sepsis in the intensive care unit (ICU) (sepsis survivors) have an increased risk of long-term mortality and ICU readmission. We aim to identify the risk factors for in-hospital mortality in sepsis survivors with later ICU readmission and visualize the quantitative relationship between the individual risk factors and mortality by applying machine learning (ML) algorithm.; Methods: Data were obtained from the Medical Information Mart for Intensive Care III (MIMIC-III) database for sepsis and non-sepsis ICU survivors who were later readmitted to the ICU. The data on the first da...
Source: Current Awareness Service for Health (CASH) - June 9, 2021 Category: Consumer Health News Source Type: news

A comprehensive systematic review of the therapeutic effects and mechanisms of action of quercetin in sepsis
Conclusion: Due to the promising therapeutic effects of quercetin on sepsis complications and the lack of clinical trials in this regard, future human randomized clinical trials are warranted. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - June 9, 2021 Category: Consumer Health News Source Type: news

Silent existence of eosinopenia in sepsis: a systematic review and meta-analysis
Conclusions: Our findings suggested that Eosinopenia has a high incidence in sepsis but has no superiority in comparison with conventional biomarkers for diagnosis of sepsis. Howev er, eosinopenia can still be used in clinical diagnosis for sepsis as a simple, convenient, fast and inexpensive biomarker. Therefore, further large clinical trials are still needed to re-evaluate eosinopenia as a biomarker of sepsis. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - June 9, 2021 Category: Consumer Health News Source Type: news

Mayo Clinic Q & amp;A podcast: A dangerous phase of the COVID-19 pandemic for those unvaccinated
If you've been vaccinated for COVID-19, you're able to go shopping, eat in restaurants and travel on airplanes without the same worry of becoming infected with COVID-19 that existed just months ago. But for those who are unvaccinated, getting infected with COVID-19 -- even with just minor symptoms -- should be a concern, according to Dr. Gregory [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - June 9, 2021 Category: Databases & Libraries Source Type: news

Mayo Clinic Q and A: Viral skin bumps that are a common occurrence in childhood
DEAR MAYO CLINIC: My 7-year-old son developed a small pink bump on his arm recently. Soon we started noticing more on his back and under his arms. His pediatrician said they were called "molluscum," and we didn't have to do anything about them. But I am worried about them spreading to his little sister. What are [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - June 9, 2021 Category: Databases & Libraries Source Type: news

Consumer Health: Treating cluster headaches
June is Migraine and Headache Awareness Month, which makes this a good time to learn more about one of the most painful types of headache: the cluster headache. Cluster headaches occur in cyclical patterns or cluster periods that can last from weeks to months. During a cluster period, headaches usually occur daily, sometimes several times [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - June 9, 2021 Category: Databases & Libraries Source Type: news

For Gyms With Tight Spaces, Expansion of a Different Sort
From on-demand video libraries to rooftop classes, the pandemic broadened how boutique workout spots operate. (Source: NYT Health)
Source: NYT Health - June 8, 2021 Category: Consumer Health News Authors: John Hanc Tags: Exercise Shutdowns (Institutional) Coronavirus (2019-nCoV) Videophones and Videoconferencing Small Business Quarantine (Life and Culture) Health Clubs Source Type: news

Library of Congress gets health workers' audio COVID diaries
The Library of Congress has acquired a digital archive of the real-time impressions of more than 200 frontline health care workers documenting the country’s descent into the COVID-19 pandemic (Source: ABC News: Health)
Source: ABC News: Health - June 8, 2021 Category: Consumer Health News Tags: Health Source Type: news

NLM Technical Bulletin, May-Jun 2021, RxNorm June 2021 Release
The RxNorm June monthly release became available for download on Monday, June 7, 2021. (Source: NLM Technical Bulletin)
Source: NLM Technical Bulletin - June 8, 2021 Category: Databases & Libraries Source Type: news

NNLM Region 6 Launch Webinar
June 23, 2:00 – 3:00 CT Come hear about plans for the “new” Region 6 Regional Medical Library (RML). You’ll get to meet staff, hear about some exciting new plans and initiatives, learn about our subaward timeline, and share your comments, questions, and feedback! We hope you can join us.   Join from a PC, Mac, iPad, iPhone or Android device: Please click this URL to join. https://uiowa.zoom.us/j/96741525353?pwd=MVp2SGdqSHEyRmNtWUxwc2RhQVNSUT09 Passcode: NNLMR6 Or join by phone: Dial(for higher quality, dial a number based on your current location): US: +1 312 626 6799  or +1 646 876 9923&...
Source: The Cornflower - June 8, 2021 Category: Databases & Libraries Authors: Miles Dietz-Castel Tags: Blog Source Type: news

Springer Nature and LYRASIS announce open access sponsorship agreement for books
(Springer) Springer Nature has signed its first sponsorship agreement for open access books with LYRASIS, a US non-profit membership association of libraries, archives, and museums, starting in 2021. The agreement is set to lead to the publication of new open access book titles. The collaboration will focus on climate change, equity, peace, and justice and will provide free access to research in critical areas that support the UN Sustainable Development Goals (SDGs). (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 8, 2021 Category: International Medicine & Public Health Source Type: news

Cell Reports publishes data supporting the importance of ion channel, Kv7.2/7.3 as a target in ALS
(LaVoieHealthScience) QurAlis Corporation today announced the publication of an article in Cell Reports titled Human Amyotrophic Lateral Sclerosis Excitability Phenotype Screen: Target Discovery and Validation by QurAlis founders Kasper Roet, Ph.D., Clifford Woolf, M.D., Ph.D., and Kevin Eggan, Ph.D., who pioneered a high-content, live-cell imaging screen using ALS patient-derived motor neurons in combination with a compound library generated by Pfizer to identify drug targets to treat hyperexcitability induced neurodegeneration in ALS patients. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 8, 2021 Category: International Medicine & Public Health Source Type: news

Metabolic perturbations sensitize triple-negative breast cancers to apoptosis induced by BH3 mimetics
Cancer cells have differential metabolic dependencies compared to their nonmalignant counterparts. However, few metabolism-targeting compounds have been successful in clinical trials. Here, we investigated the metabolic vulnerabilities of triple-negative breast cancer (TNBC), particularly those metabolic perturbations that increased mitochondrial apoptotic priming and sensitivity to BH3 mimetics (drugs that antagonize antiapoptotic proteins). We used high-throughput dynamic BH3 profiling (HT-DBP) to screen a library of metabolism-perturbing small molecules, which revealed inhibitors of the enzyme nicotinamide phosphoribosy...
Source: Signal Transduction Knowledge Environment - June 8, 2021 Category: Science Authors: Daniels, V. W., Zoeller, J. J., van Gastel, N., McQueeney, K. E., Parvin, S., Potter, D. S., Fell, G. G., Ferreira, V. G., Yilma, B., Gupta, R., Spetz, J., Bhola, P. D., Endress, J. E., Harris, I. S., Carrilho, E., Sarosiek, K. A., Scadden, D. T., Brugge, Tags: STKE Research Articles Source Type: news

‘Blacklist’ claim: Australian Research Council admits scanning applicants for ‘sensitivities’, China links
Research grant applicants ‘entitled to know’ if there is a secret blacklist operating: former research minister Kim CarrAn Australian government agency has been accused of running a secret “blacklist” on researchers by scanning for information about individuals who apply to it for grants.The Australian Research Council has confirmed it collates information about potential “sensitivities” when it prepares funding decisions, including media reports and links to Chinese institutions listed on a database compiled by the Australian Strategic Policy Institute (Aspi).Continue reading... (Source...
Source: Guardian Unlimited Science - June 7, 2021 Category: Science Authors: Daniel Hurst Tags: Science Research and development Source Type: news

Predicted number of pregnant women in Aichi Prefecture, Japan: estimation by machine learning database construction for disaster preparation - Hattori K, Hattori R.
Aichi prefecture, Japan is predicted to be hit by Mega-earthquake. Aichi Prefectural Association of Midwives has been making efforts to improve disaster preparedness for pregnant women. This project aims to acquire area data of pregnant women for simulated... (Source: SafetyLit)
Source: SafetyLit - June 7, 2021 Category: International Medicine & Public Health Tags: Disaster Preparedness Source Type: news

The psychological experiences of nurses after inpatient suicide: a meta-synthesis of qualitative research studies - Shao Q, Wang Y, Hou K, Zhao H, Sun X.
AIMS: To explore nurses' psychological experiences after inpatient suicide. DESIGN: Qualitative studies were meta-synthesized. DATA SOURCES: Eight databases (PubMed, Web of Science, CINAHL, Embase, Wanfang Data, VIP database, CBM and CNKI) were sea... (Source: SafetyLit)
Source: SafetyLit - June 7, 2021 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

A qualitative systematic review on nurses' experiences of workplace bullying and implications for nursing practice - Shorey S, Wong PZE.
AIMS: To explore nurses' experiences of workplace bullying and ways to prevent such occurrences. DESIGN: A qualitative systematic review was conducted. DATA SOURCES: Five electronic databases were searched from each database's inception to December... (Source: SafetyLit)
Source: SafetyLit - June 7, 2021 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Association between diet and symptoms of anxiety and depression in college students: a systematic review - Saha S, Okafor H, Biediger-Friedman L, Behnke A.
OBJECTIVE: To gather research evidence on the association between diet and depression and anxiety among college students. METHODS: Systematic searches were performed in CINAHL, PsycINFO, PubMed, and ScienceDirect databases to identify potentially r... (Source: SafetyLit)
Source: SafetyLit - June 7, 2021 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

For Small Gyms, Handling the Pandemic Meant Expanding
From on-demand video libraries to rooftop classes, boutique workout spots broadened beyond their tight spaces. (Source: NYT Health)
Source: NYT Health - June 7, 2021 Category: Consumer Health News Authors: John Hanc Tags: Exercise Shutdowns (Institutional) Coronavirus (2019-nCoV) Videophones and Videoconferencing Small Business Quarantine (Life and Culture) Health Clubs Source Type: news