High-Grade Serous Ovarian Cancer during Pregnancy: From Diagnosis to Treatment
CONCLUSIONS: There have not been long-term follow-ups of patients' oncologic and obstetric outcomes. As patients should be comprehensively informed, more detailed case reports or series with longer follow-up periods are needed.PMID:38668047 | DOI:10.3390/curroncol31040144 (Source: Current Oncology)
Source: Current Oncology - April 26, 2024 Category: Cancer & Oncology Authors: Gregor Vivod Sebastjan Merlo Nina Kovacevic Source Type: research
The Efficacy of Fat Grafting on Treating Post-Mastectomy Pain with and without Breast Reconstruction: A Systematic Review and Meta-Analysis
Curr Oncol. 2024 Apr 4;31(4):2057-2066. doi: 10.3390/curroncol31040152.ABSTRACTPost-mastectomy pain syndrome (PMPS), characterized by persistent pain lasting at least three months following mastectomy, affects 20-50% of breast surgery patients, lacking effective treatment options. A review was conducted utilizing EMBASE, MEDLINE, and all evidence-based medicine reviews to evaluate the effect of fat grafting as a treatment option for PMPS from database inception to 29 April 2023 (PROSPERO ID: CRD42023422627). Nine studies and 812 patients in total were included in the review. The overall mean change in visual analog scale (...
Source: Current Oncology - April 26, 2024 Category: Cancer & Oncology Authors: Jeffrey Chen Abdulrahman A Alghamdi Chi Yi Wong Muna F Alnaim Gabriel Kuper Jing Zhang Source Type: research
Overexpression of ZNF169 promotes the growth and proliferation of colorectal cancer cells via the upregulation of ANKZF1
Oncol Rep. 2024 Jun;51(6):82. doi: 10.3892/or.2024.8741. Epub 2024 Apr 26.ABSTRACTColorectal cancer (CRC) is one of the most common malignancies worldwide. The 5‑year survival rate of patients diagnosed with the early stages of the disease is markedly higher than that of patients in the advanced stages. Therefore, identifying novel biomarkers and drug targets for CRC is critical for clinical practice. Zinc finger protein 169 (ZNF169) is a crucial transcription factor, and its role in CRC remains to be explored. The present study aimed to investigate the clinical relevance, function and underlying mechanisms of ZNF169 in ...
Source: Oncology Reports - April 26, 2024 Category: Cancer & Oncology Authors: Jie Zhang Ye Wang Shiyang Hou Xiaoqian Chi Danyang Ding Mei Xue Mengqiao Zhang Jing Wang Junfang Shuai Haiying Sun Qiang Gao Chunbo Kang Source Type: research
A Rare Early-Onset Fatal Complication after Transarterial Chemoembolization: A Case Report and Review of the Literature
In conclusion, this case underscores the importance of recognizing the rare complication of HCC rupture post-TACE and the need for personalized risk assessment. While TAE emerges as a primary treatment choice, the lack of consensus necessitates further studies to establish evidence-based approaches for managing this uncommon yet life-threatening complication.PMID:38668050 | DOI:10.3390/curroncol31040147 (Source: Current Oncology)
Source: Current Oncology - April 26, 2024 Category: Cancer & Oncology Authors: Monika P éčová Jakub Benko Martin Jozef P éč Jakub Jurica Simona Horn á Tom áš Bolek Tatiana Hurtov á J án Sýkora Kamil Zele ňák Matej Samo š Juraj Sokol Source Type: research
Tailored Carbon Dioxide Capacity in Carboxylate-Based Ionic Liquids †
Faraday Discuss., 2024, Accepted Manuscript DOI: 10.1039/D4FD00052H, PaperNicolas Scaglione, Jocasta Avila, Agilio A.H. Padua, Margarida Costa Gomes We used a library of thermally stable tetraalkylphosphonium carboxylate ILs that were easily pre- pared from available carboxylic acids. Depending on the 𝑝𝐾𝑎 of the precursor acids, the resulting ionic... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Faraday Discuss. latest articles)
Source: RSC - Faraday Discuss. latest articles - April 26, 2024 Category: Chemistry Authors: Nicolas Scaglione Source Type: research
Efficacy of catheter ablation for atrial fibrillation in heart failure: a meta ‐analysis of randomized controlled trials
AbstractThe study aims to evaluate whether rhythm control by catheter ablation is superior to medical therapy for the patients with atrial fibrillation (AF) and heart failure (HF). The literatures were searched by using PubMed, Cochrane Library, Embase, and Web of Science databases up to 12 October 2023. The randomized controlled trials (RCTs) comparing rhythm control using catheter ablation vs. medical therapy in AF patients with HF were pooled. The primary outcomes included all-cause mortality, HF re-hospitalization, and stroke, and the secondary outcomes included left ventricular ejection fraction (LVEF), atrial tachyar...
Source: ESC Heart Failure - April 26, 2024 Category: Cardiology Authors: Zhongyin Zhang,
Yan Zheng,
Wenxiu He,
Jiahe Wei,
Pengzhan Li,
Guoqiang Zhong,
Zhiyuan Jiang Tags: Review Source Type: research
Immunocompromised individuals are at increased risk of COVID ‐19 breakthrough infection, hospitalization, and death in the post‐vaccination era: A systematic review
ConclusionThis demonstrated that vaccination does not offer an adequate level of protection in these groups, necessitating further measures such as Evusheld and further boosters. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - April 26, 2024 Category: Allergy & Immunology Authors: Jola Bytyci,
Yuxin Ying,
Lennard Y. W. Lee Tags: REVIEW ARTICLE Source Type: research
Left bundle branch area pacing using a lumenless lead: A systematic literature review and meta ‐analysis
ConclusionThis meta-analysis including 6061 patients implanted with a Model 3830 lead for LBBAP found an average implant success rate of 92.7% and a procedural adverse event rate of 2.5% with stable electrical parameters and LVEF post-implant. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - April 26, 2024 Category: Cardiology Authors: Kenneth A. Ellenbogen,
Dedra H. Fagan,
Patrick Zimmerman,
Pugazhendhi Vijayaraman Tags: ORIGINAL ARTICLE Source Type: research
Exercise ‐induced changes in central sensitization outcomes in individuals with chronic musculoskeletal pain: A systematic review with meta‐analysis
ConclusionsWe did not find an overall effect of physical exercise on TSP and CPM. However, subgroup analysis shows favourable effects of motor control exercise in individuals with chronic neck pain. Future research should focus on exercise modality and dosage and their role in the mechanism involved in TSP and CPM in predefined populations.Significance StatementResults from this study found that motor control exercise has a significant enhancing effect on conditioned pain modulation, with subgroup analysis showing favourable effects of motor control exercise in individuals with chronic neck pain. This indicates that physic...
Source: European Journal of Pain - April 26, 2024 Category: Anesthesiology Authors: Kexun Kenneth Chen,
Paul Rolan,
Mark Rowland Hutchinson,
Cameron Dickson,
Rutger Marinus Johannes de Zoete Tags: REVIEW ARTICLE Source Type: research
Adjunctive low ‐voltage area ablation for patients with atrial fibrillation: An updated meta‐analysis of randomized controlled trials
ConclusionsAdjunctive LVA ablation is an effective and safe strategy for reducing recurrences of ATA among patients who undergo CA for AF. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - April 26, 2024 Category: Cardiology Authors: Andr é Rivera,
Douglas M. Gewehr,
Marcelo A. P. Braga,
Pedro E. P. Carvalho,
Caique M. P. Ternes,
Alexandre N. Pantaleao,
Daniela Hincapie,
Frans Serpa,
Jorge E. Romero,
André d'Avila Tags: ORIGINAL ARTICLE Source Type: research
Prognostic nutritional index as a predictive marker for acute kidney injury in adult critical illness population: a systematic review and diagnostic test accuracy meta-analysis
ConclusionOur study demonstrated that PNI has practical accuracy for predicting the development of AKI in critically ill populations, with superior diagnostic performance observed in medical and non-CKD populations. However, the diagnostic efficacy of the PNI has significant heterogeneity with different cutoff value, indicating the need for further research. (Source: Journal of Intensive Care)
Source: Journal of Intensive Care - April 26, 2024 Category: Intensive Care Source Type: research
Robotic-assisted hysterectomy for benign gynecologic disease in the United States: in-hospital use of opioid and non-opioid analgesics
AbstractTo compare the in-hospital opioid and non-opioid analgesic use among women who underwent robotic-assisted hysterectomy (RH) vs. open (OH), vaginal (VH), or laparoscopic hysterectomy (LH). Records of women in the United States who underwent hysterectomy for benign gynecologic disease were extracted from the Premier Healthcare Database (2013 –2019). Propensity score methods were used to create three 1:1 matched cohorts stratified in inpatients [RH vs. OH (N = 16,821 pairs), RH vs. VH (N = 6149), RH vs. LH (N = 11,250)] and outpatients [RH vs. OH (N = 3139), RH vs. VH (N = 29,954), RH vs. LH (N...
Source: Journal of Robotic Surgery - April 26, 2024 Category: Surgery Source Type: research
The chromosomal characteristics of spontaneous abortion and its potential associated copy number variants and genes
ConclusionWe found variability in chromosomal abnormalities across clinical features, identifying eight crucial copy number variations (CNVs) and multiple key genes that may be linked to spontaneous abortion. This research enhances the comprehension of genetic factors contributing to spontaneous abortion. (Source: Journal of Assisted Reproduction and Genetics)
Source: Journal of Assisted Reproduction and Genetics - April 26, 2024 Category: Reproduction Medicine Source Type: research
Effectiveness of photobiomodulation therapy in the treatment of patients with an ankle sprain: a systematic review and meta-analysis
ConclusionPBMT is quite effective for patients with an ankle sprain. PBMT showed high effect size with a moderate level of evidence on pain intensity. The lack of significant effects of PBMT on function and edema with low level of evidence limit the confidence to the current results and recommend further large high-quality studies with higher PBMT intensity and fluency for standardisation of the irradiation parameters and treatment protocol.RegistrationPROSPERO registration number (CRD42021292930). (Source: Lasers in Medical Science)
Source: Lasers in Medical Science - April 26, 2024 Category: Laser Surgery Source Type: research
Two metastable high hydrates of energetic material 3,3 ′ ,5,5 ′ -tetranitro-4,4 ′ -bipyrazole
Poly-stoichiometry of hydrated phases is relatively uncommon for organic materials and extended libraries of such species adopting different aqua-to-substrate ratios are still rare. The kinetically controlled higher hydrates could be particularly interesting for their structural relationships, which presumably may imprint some features of the substrate/substrate and aqua/substrate bonding in solutions, and provide insights into the nucleation stage. Two metastable high hydrates are prepared by crash crystallization. The crystal structures of 3,3 ′ ,5,5 ′ -tetranitro-4,4 ′ -bipyrazole tetrahydrate, C6H2N8O8 · 4H2O, (...
Source: Acta Crystallographica Section C - April 26, 2024 Category: Chemistry Authors: Domasevitch, K.V. Krautscheid, H. Tags: molecular hydrate hydrogen bonding N-heterocyclic aromatic compound nitro compounds lone pair – π -hole interaction crystal structure Ostwald rule research papers Source Type: research
