Exercise ‐induced changes in central sensitization outcomes in individuals with chronic musculoskeletal pain: A systematic review with meta‐analysis
ConclusionsWe did not find an overall effect of physical exercise on TSP and CPM. However, subgroup analysis shows favourable effects of motor control exercise in individuals with chronic neck pain. Future research should focus on exercise modality and dosage and their role in the mechanism involved in TSP and CPM in predefined populations.Significance StatementResults from this study found that motor control exercise has a significant enhancing effect on conditioned pain modulation, with subgroup analysis showing favourable effects of motor control exercise in individuals with chronic neck pain. This indicates that physic...
Source: European Journal of Pain - April 26, 2024 Category: Anesthesiology Authors: Kexun Kenneth Chen,
Paul Rolan,
Mark Rowland Hutchinson,
Cameron Dickson,
Rutger Marinus Johannes de Zoete Tags: REVIEW ARTICLE Source Type: research
Short all ‐out isokinetic cycling exercises of 90 and 15 s unlock exercise‐induced hypoalgesia
ConclusionGlobal EIH assessed immediately after exercise can be induced by short highly intensive exercises. The effects are greater when the subjective and the objective exertion are higher as induced by the 90 s intervention.Significance StatementThis study investigates the potential for brief, highly intensive exercise sessions to induce exercise-induced hypoalgesia (EIH). The research demonstrates that EIH can indeed be triggered by such short workouts, with greater effects observed during a 90 s session compared to a 15 s one, most likely due to higher subjective and objective exertion. These findings offer insight...
Source: European Journal of Pain - April 18, 2024 Category: Anesthesiology Authors: Fabian Tomschi,
Jana Schulz,
Holger Stephan,
Thomas Hilberg Tags: ORIGINAL ARTICLE Source Type: research
Clinicians diagnosing virtual patients with the classification algorithm for chronic pain in the ICD ‐11 (CAL‐CP) achieve better diagnoses and prefer the algorithm to standard tools: An experimental validation study
ConclusionsThe use of the algorithm increases the correctness of the diagnoses for chronic pain and is well accepted by clinicians. The CAL-CP's use should be considered in routine care and research contexts.Significance StatementThe ICD-11 has come into effect in January 2022. Clinicians and researchers will soon begin using the new classification of chronic pain. To facilitate clinicians training and diagnostic accuracy, a classification algorithm was developed. The paper investigates whether clinicians using the algorithm —as opposed to the generic tools provided by the WHO—reach more correct diagnoses when they dia...
Source: European Journal of Pain - April 17, 2024 Category: Anesthesiology Authors: Ginea Hay,
Beatrice Korwisi,
Norman Lahme ‐Hütig,
Winfried Rief,
Antonia Barke Tags: ORIGINAL ARTICLE Source Type: research
Issue Information
(Source: European Journal of Pain)
Source: European Journal of Pain - April 17, 2024 Category: Anesthesiology Tags: ISSUE INFORMATION Source Type: research
Pain perception during baroreceptor unloading by lower body negative pressure
ConclusionTherefore, baroreceptor unloading with maintained systemic blood pressure did not alter pain perception. The current study does not support the hypothesis that an altered baroreflex may underlie the physiological mechanism of blood pressure-related hypoalgesia.SignificanceThis work provides evidence that, when measured in normotensive healthy young adults, the baroreflex response to simulated hypovolaemia did not lead to reduced pain sensitivity (known as blood pressure hypoalgesia). (Source: European Journal of Pain)
Source: European Journal of Pain - April 16, 2024 Category: Anesthesiology Authors: S. Neumann,
M. C. K. Hamilton,
E. C. Hart,
J. C. W. Brooks Tags: ORIGINAL ARTICLE Source Type: research
Systematic reviews and quality assessment of patient ‐reported outcome measures for physical function in comparative effectiveness studies regarding acute postoperative pain after total knee arthroplasty—Do we need to start all over again?
ConclusionOur data indicate that a patient-centred postoperative assessment of PF in pain-related clinical trials early after TKA is not common, even though patient-reported assessment is widely recommended. In addition, none of the applied PROMs shows content validity based on their inauguration or development articles for the assessment of postoperative pain-related PF after TKA.SignificanceA systematic search for patient-reported outcome measures assessing postoperative, pain-related physical function after total knee arthroplasty in clinical trials and assessment of their content validity revealed none that fulfilled r...
Source: European Journal of Pain - April 16, 2024 Category: Anesthesiology Authors: H. Heitkamp,
D. Heu ßner,
D. C. Rosenberger,
K. Schnabel,
D. Rosenthal,
S. Bigalke,
T. V. Maeßen,
D. Hohenschurz‐Schmidt,
H. Liedgens,
U. Kaiser,
E. M. Pogatzki‐Zahn Tags: REVIEW ARTICLE Source Type: research
Vagal tone, pain sensitivity and exercise ‐induced hypoalgesia: The effect of physical activity level
ConclusionsHighly active individuals demonstrate greater vagal tone and lower pain sensitivity but no greater EIH. Vagal tone moderates pain inhibition efficiency and EIH only in low –moderately active individuals. These findings suggest that physical activity level moderates the vagal–pain association via the endogenous analgesia system.SignificanceHighly physically active individuals exhibit greater vagal tone and reduced sensitivity to experimental pain, yet they do not benefit more from exercise-induced hypoalgesia (EIH) compared to low –moderately active individuals. Moreover, low–moderately active individuals...
Source: European Journal of Pain - April 13, 2024 Category: Anesthesiology Authors: Ela Michaeli Izak,
Einat Kodesh,
Irit Weissman‐Fogel Tags: ORIGINAL ARTICLE Source Type: research
Time trends in opioid use for patients undergoing hip fracture surgery in 1997 –2018: A Danish population‐based cohort study
ConclusionThe PRs of opioid use in Q1 after surgery increased substantially from 1997 to 2018, but this did not translate into increased opioid use up to 1 year after hip fracture surgery or higher dosage. Our findings underline the importance of sustained focus on opioid tapering, dosage and use of opioids with the lowest potential for addiction and other adverse events.Significance StatementOverall, opioid use in Q1 after hip fracture surgery increased 2.7 times from 1997 to 2018, but the doses and opioid use up to 1 year after surgery remained stable. Compared to elderly, younger patients were more likely to use o...
Source: European Journal of Pain - April 7, 2024 Category: Anesthesiology Authors: I. M. Melsen,
S. K. Sz épligeti,
P. H. Gundtoft,
A. B. Pedersen Tags: ORIGINAL ARTICLE Source Type: research
The prevalence, incidence and management of low back pain with radiating leg pain in Dutch general practice: A population ‐based cohort study in the Rijnmond Primary Care Database
ConclusionLBP with radiating leg pain is common in Dutch general practice patients. About 2/3rd were prescribed pain medications. Dutch request few to none diagnostic imaging for these patients which is in line with clinical practice guidelines.SignificanceIn this new study, we have gained insights into the incidence and prevalence of LBP with radiating leg pain in Dutch general practice. Both remained fairly stable over the study period of 9 years (2013–2021). Overall, the care burden regarding seeking contact with the GPs and the requested diagnostics seem not to be that high. In 62% of the care episodes, there were...
Source: European Journal of Pain - April 5, 2024 Category: Anesthesiology Authors: Ahmad Khoshal Khorami,
Alessandro Chiarotto,
Evelien I. T. de Schepper,
Patrick J. E. Bindels,
Bart W. Koes,
Jacoline J. van den Driest Tags: ORIGINAL ARTICLE Source Type: research
Effects of chronic daily headache with subclinical depression on brain volume: A systematic review and meta ‐analysis
ConclusionsPain-induced persistent depressive symptoms not only incur structural alterations but also encompass affective-motivational changes, involving medication use and gender-specific health concerns.SignificanceThis study highlighted the importance of an integrated CDH treatment, emphasizing psychological interventions for the affective-motivational component alongside pain management. (Source: European Journal of Pain)
Source: European Journal of Pain - April 2, 2024 Category: Anesthesiology Authors: Chih ‐Lung Lin,
Hsien‐Yuan Lane,
Cheuk‐Kwan Sun,
Meng‐Hsiang Chen,
Chiao‐Yu Lee,
Lin Li,
Jia‐Jie Lee,
Pin‐Yang Yeh Tags: REVIEW ARTICLE Source Type: research
Emotion regulation skills ‐focused interventions for chronic pain: A systematic review and meta‐analysis
AbstractObjectivesTo investigate the effect of emotion regulation skills-focused (ERSF) interventions to reduce pain intensity and improve psychological outcomes for people with chronic pain and to narratively report on safety and intervention compliance.MethodsSix databases and four registries were searched for randomized controlled trials (RCTs) up to 29 April 2022. Risk of bias was evaluated using the Cochrane RoB 2.0 tool, and certainty of evidence was assessed according to the Grading, Assessment, Development and Evaluation (GRADE). Meta-analyses for eight studies (902 participants) assessed pain intensity (primary ou...
Source: European Journal of Pain - April 2, 2024 Category: Anesthesiology Authors: Nell Norman ‐Nott,
Negin Hesam‐Shariati,
Michael A. Wewege,
Rodrigo R. N. Rizzo,
Aidan G. Cashin,
Chelsey R. Wilks,
Yann Quidé,
James H. McAuley,
Sylvia M. Gustin Tags: REVIEW ARTICLE Source Type: research
Pain trajectories and neuropathic pain symptoms following lung cancer surgery: A prospective cohort study
ConclusionsThree clinically relevant recovery trajectories were identified, based on comprehensive pain tracking. Higher acute postoperative pain intensity was associated with an unfavourable pain recovery trajectory.Significance StatementUnderstanding the transition from acute to chronic postoperative pain and identifying preoperative risk factors is essential for the development of targeted treatments and the implementation of preventive measures. This study (1) identified distinct recovery trajectories based on frequent pain assessment follow-ups for 12 months after surgery and (2) evaluated risk factors for unfavour...
Source: European Journal of Pain - March 26, 2024 Category: Anesthesiology Authors: A. V. Danielsen,
J. J. Andreasen,
B. Dinesen,
J. Hansen,
K. K. Petersen,
K. S. Duch,
J. Bisgaard,
C. Simonsen,
L. Arendt ‐Nielsen Tags: ORIGINAL ARTICLE Source Type: research
Reliability of a clinical sensory test battery in patients with spine ‐related leg and arm pain
ConclusionCST modalities with moderate to substantial inter-tester reliability could be of benefit as a screening tool. The moderate to substantial intra-tester reliability for all sensory modalities (except windup ratio) supports their potential use in clinical practice and research to monitor somatosensory changes over time in patients with spine-related limb pain of mixed pain mechanisms.SignificanceWe already know that most modalities of clinical sensory test (CST) batteries achieve moderate to substantial inter- and intra-tester reliability in populations with neuropathic pain.This study evaluates the reliability of a...
Source: European Journal of Pain - March 25, 2024 Category: Anesthesiology Authors: Cedric Bender,
Sven Karstens,
Fabian Muth,
Georgios Baskozos,
Annina B. Schmid Tags: ORIGINAL ARTICLE Source Type: research
Comparison between the effects of epidural and intravenous patient ‐controlled analgesia on postoperative disability‐free survival in patients undergoing thoracic and abdominal surgery: A post hoc analysis
ConclusionNo significant differences were observed in the disability-free survival at 3 months and 1 year after elective thoracic and abdominal surgery in patients aged ≥55 years who received TEA or IV-PCA.Significance statementThis study is the first in our setting to document the long-term effects of patient-controlled analgesia. In a post hoc analysis of our prospective cohort study, we show that although differences in chronic postsurgical pain exist at 3 months post-surgery, disability-free survival rates at 1 year do not differ irrespective of the choice of patient-controlled analgesia. The findings of ...
Source: European Journal of Pain - March 22, 2024 Category: Anesthesiology Authors: S. Hirai,
M. Ida,
Y. Naito,
M. Kawaguchi Tags: ORIGINAL ARTICLE Source Type: research
Issue Information
(Source: European Journal of Pain)
Source: European Journal of Pain - March 18, 2024 Category: Anesthesiology Tags: ISSUE INFORMATION Source Type: research
