Thin ‐fibre receptors expressing acid‐sensing ion channel 3 contribute to muscular mechanical hypersensitivity after exercise
ConclusionsThese results clearly indicate that ASIC3 contributes to the augmented mechanical response of muscle thin ‐fibre receptors in delayed onset muscular mechanical hypersensitivity after LC.This article is protected by copyright. All rights reserved. (Source: European Journal of Pain)
Source: European Journal of Pain - July 17, 2019 Category: Anesthesiology Authors: Takanori Matsubara, Koei Hayashi, Koji Wakatsuki, Masahiro Abe, Noriyuki Ozaki, Akihiro Yamanaka, Kazue Mizumura, Toru Taguchi Tags: Original Article Source Type: research

The effect of intradermal microdosing of a transient receptor potential cation channel subfamily V member 1 antagonist on heat evoked pain and thermal thresholds in normal and ultraviolet ‐C exposed skin in healthy volunteers
ConclusionsThis study validated translational tools to confirm target engagement for TRPV1 antagonists; WDT, HPT and STHP have utility in this respect, after oral administration of a TRPV1 antagonist. This study also proved that TRPV1 antagonists can inhibit a more complex, non ‐capsaicin dependent thermally induced pain signal.This article is protected by copyright. All rights reserved. (Source: European Journal of Pain)
Source: European Journal of Pain - July 17, 2019 Category: Anesthesiology Authors: Erik Sj ögren, Lars Ståhle, Hans Quiding, Bror Jonzon, Magnus M. Halldin, Anna K. Sundgren Tags: Original Article Source Type: research

Nerve growth factor ‐induced muscle hyperalgesia facilitates ischemic contraction‐evoked pain
AbstractBackgroundIntramuscular injection of Nerve Growth Factor (NGF) may influence the responsiveness of active chemo ‐sensitive channels affecting muscle pain sensitivity. This double‐blinded crossover study in healthy humans assessed contraction‐evoked pain responses and pain sensitivity during acute ischemia in the tibialis anterior (TA) muscle before and 24h after five distributed NGF injections (1μg, 4 cm interval) compared with control injections (isotonic‐saline).MethodsTwenty ‐one subjects participated in two experimental phases, each including 5 sessions over 7 days, with a gap of 4 weeks in‐betwe...
Source: European Journal of Pain - July 17, 2019 Category: Anesthesiology Authors: L. B. S ørensen, P. Gazerani, T. Graven‐Nielsen Tags: Original Article Source Type: research

Corrigendum
European Journal of Pain, Volume 23, Issue 7, Page 1397-1397, August 2019. (Source: European Journal of Pain)
Source: European Journal of Pain - July 15, 2019 Category: Anesthesiology Tags: CORRIGENDUM Source Type: research

Issue Information
European Journal of Pain, Volume 23, Issue 7, Page 1223-1224, August 2019. (Source: European Journal of Pain)
Source: European Journal of Pain - July 15, 2019 Category: Anesthesiology Tags: ISSUE INFORMATION Source Type: research

The relation between parental chronic pain, pain ‐related attention and interpretation biases in pain‐free adolescents
ConclusionsFuture research is needed to further elucidate the precise role of parental pain in the development of pain ‐related biases and the significance of these biases in the onset and/or maintenance of a chronic pain condition in children and adolescents.SignificanceParental chronic pain may install psychological vulnerability for developing chronic pain and associated complaints in offspring. This study did not show differences in pain ‐directed attentional and interpretation bias between offspring of parents with chronic pain complaints and offspring of pain‐free parents. Further (longitudinal) research is nee...
Source: European Journal of Pain - July 15, 2019 Category: Anesthesiology Authors: Jantine J. L. M. Boselie, Mari ëlle E. J. B. Goossens, Peter Muris, Linda M. G. Vancleef Tags: ORIGINAL ARTICLE Source Type: research

Perception of phasic pain is modulated by smell and taste
ConclusionsThese findings highlight an effect of sweet substances in reducing the subjective perception of pain intensity and unpleasantness associated to phasic pain.This article is protected by copyright. All rights reserved. (Source: European Journal of Pain)
Source: European Journal of Pain - July 10, 2019 Category: Anesthesiology Authors: M. Riello, M.P. Cecchini, A. Zanini, M. Di Chiappari, M. Tinazzi, M. Fiorio Tags: Original Article Source Type: research

Age ‐related differences in the acute pain facial expression during infancy
ConclusionsFacial expressions illustrating intense/moderate distress and sensory overload were prominent in the first 15  s at the 2‐, 4‐ and 6‐month vaccination. However, expressions showing regulation of distress occurred progressively earlier over 1 min post‐needle in older infants, suggesting a significant shift in regulatory capacity of pain‐related distress occurs after 6‐months of age.SignificanceAn important developmental milestone was identified in infants' ability to regulate distress at 6  months. Supporting parents' infant pain management is particularly critical in the first months o...
Source: European Journal of Pain - July 3, 2019 Category: Anesthesiology Authors: Monica C. O'Neill, Sara Ahola Kohut, Rebecca Pillai Riddell, Harriet Oster Tags: ORIGINAL ARTICLE Source Type: research

Commentary on “Cognitive Functional Therapy in Patients with Non‐Specific Chronic Low Back Pain”
European Journal of Pain, EarlyView. (Source: European Journal of Pain)
Source: European Journal of Pain - July 2, 2019 Category: Anesthesiology Authors: Steven Z. George Tags: COMMENTARY Source Type: research

Pain over the adult life course: 15 year ‐pain trajectories ‐ the Doetinchem Cohort Study
ConclusionsA substantial part of the population reports pain over a long period of their life course and long ‐term trajectories of pain may reflect phenotypes that may be relevant to take into account in pain management. Several risk factors, such as short sleep duration, smoking, obesity and poor perceived or mental health may be relevant in recognizing those with pain, and tackling these may contribute to the prevention of pain over the life course.SignificanceAsking adults about pain every 5 years over a 15 ‐year period shows that almost one‐third never reported pain and one‐fifth persistent pain. ‘Persis...
Source: European Journal of Pain - July 1, 2019 Category: Anesthesiology Authors: H. Susan J. Picavet, W. M. Monique Verschuren, Lichelle Groot, Laura Schaap, Sandra H. van Oostrom Tags: Original Article Source Type: research

A new experimental model of muscle pain in humans based on short ‐wave diathermy
ConclusionsSWD was able to elicit muscle soreness and hyperalgesia up to 60 min after its application. Thus, this new model represents a promising tool for investigating muscle pain in humans.This article is protected by copyright. All rights reserved. (Source: European Journal of Pain)
Source: European Journal of Pain - June 28, 2019 Category: Anesthesiology Authors: C.A. Mista, S. Laugero, J. Adur, O.K. Andersen, J.A. Biurrun Manresa Tags: ORIGINAL ARTICLE Source Type: research

Does the heritability of chronic low back pain depend on how the condition is assessed?
ConclusionsGenetic factors appear to significantly contribute to the variance in chronic LBP including lifetime chronic LBP, activity limitation, and pain intensity associated with more recent episodes of LBP, but not for pain intensity associated with people's report of the worst pain episode. Heritability estimates was fairly similar across different LBP outcomes in a population ‐based twin sample, and not dependent on how it is assessed or experienced. However, we could not detect any significant heritability for a report of intensity experienced during the worst LBP episode experienced.This article is protected by co...
Source: European Journal of Pain - June 27, 2019 Category: Anesthesiology Authors: Ana Paula M. C. Carvalho ‐E‐Silva, Alison R. Harmer, Marina B. Pinheiro, Juan J. Madrid‐Valero, Manuela Ferreira, Juan R. Ordoñana, Paulo H. Ferreira Tags: Original Article Source Type: research

Issue Information
European Journal of Pain, Volume 23, Issue 6, Page 1045-1046, July 2019. (Source: European Journal of Pain)
Source: European Journal of Pain - June 26, 2019 Category: Anesthesiology Tags: ISSUE INFORMATION Source Type: research

Sensory Testing Associates With Pain Quality Descriptors During Acute Dental Pain
ConclusionsThe reporting of neuropathic pain descriptors by subjects experiencing acute toothache was more frequent than expected, suggesting that neuropathic mechanisms could contribute to typical toothache pain. Subjects experiencing toothache with mechanical hypersensitivity experience more intense pain overall.This article is protected by copyright. All rights reserved. (Source: European Journal of Pain)
Source: European Journal of Pain - June 26, 2019 Category: Anesthesiology Authors: O. Erdogan, M. Malek, M. N. Janal, J. L. Gibbs Tags: Original Article Source Type: research

Ziconotide for spinal cord injury related pain
ConclusionThis study shows response to intrathecal ziconotide test in 40% of the patients of a very specific population in whom other therapeutic options are not available. This data justifies the development further studies such as a long term randomized controlled trial.This article is protected by copyright. All rights reserved. (Source: European Journal of Pain)
Source: European Journal of Pain - June 24, 2019 Category: Anesthesiology Authors: Andrei Brinzeu, Julien Berthiller, Jean ‐Bernard Caillet, Helene Staquet, Patrick Mertens Tags: ORIGINAL ARTICLE Source Type: research

Pain vs. comfort diary: A fully remote app ‐based experiment
ConclusionsThe findings do not support the potential beneficial effects of replacing diary ratings of pain intensity with diary ratings of comfort. The unexpected decreases among those who completed daily pain diaries might have been due to the inclusion of questions about expected pain. Decreasing correlations between pain and comfort ratings suggest that comfort ratings are not merely inverted pain ratings; rather, they appear to assess a domain distinct from pain intensity.This article is protected by copyright. All rights reserved. (Source: European Journal of Pain)
Source: European Journal of Pain - June 24, 2019 Category: Anesthesiology Authors: Piotr Gruszka, Christina Stammen, Nicolai Bissantz, Mark P. Jensen Tags: Original Article Source Type: research

The Central Sensitization Inventory predict pain ‐related disability for musculoskeletal disorders in the primary care setting
In this study, we investigated the association between CSI severity levels and the profiles of patients with musculoskeletal disorders as well as the longitudinal relationship between CSI severity levels and pain‐related disability in primary care settings .MethodsA total of 553 patients were assessed using CSI, EuroQol ‐5 dimension (EQ5D), and Brief Pain Inventory (BPI). Of the 553 patients, 150 patients were reassessed at the 3‐month follow‐up. Patients were grouped into three severity levels according to baseline CSI score: subclinical, mild, and moderate to higher level.ResultsAs the CSI severity levels increas...
Source: European Journal of Pain - June 24, 2019 Category: Anesthesiology Authors: Katsuyoshi Tanaka, Shunsuke Murata, Tomohiko Nishigami, Akira Mibu, Masahiro Manfuku, Yoshikazu Shinohara, Akihito Tanabe, Rei Ono Tags: Original Article Source Type: research

Cornea nerve fibre state determines analgesic response to tapentadol in fibromyalgia patients without effective endogenous pain modulation
ConclusionsIn chronic pain patients with fibromyalgia, the increase in endogenous pain inhibition by tapentadol was translated into analgesia in patients with a normal CNFS. In those with abnormal CNFS, tapentadol treatment was without analgesic effect.SignificanceIn this double ‐blind randomized placebo‐controlled trial, we showed that tapentadol significantly enhanced the descending pain inhibition in fibromyalgia patients. Tapentadol‐induced pain relief was only present in patients with a normal CNFS. (Source: European Journal of Pain)
Source: European Journal of Pain - June 24, 2019 Category: Anesthesiology Authors: Tine Donk, Monique Velzen, Albert Dahan, Marieke Niesters Tags: ORIGINAL ARTICLE Source Type: research

The relation between parental chronic pain and pain ‐related attention and interpretation biases in pain‐free adolescents
ConclusionsFuture research is needed to further elucidate the precise role of parental pain in the development of pain ‐related biases and the significance of these biases in the onset and/or maintenance of a chronic pain condition in children and adolescents.This article is protected by copyright. All rights reserved. (Source: European Journal of Pain)
Source: European Journal of Pain - June 24, 2019 Category: Anesthesiology Authors: Jantine J. L. M. Boselie, Mari ëlle E. J. B. Goossens, Peter Muris, Linda M. G. Vancleef Tags: Original Article Source Type: research

Psychological pain responses in athletes and non ‐athletes with low back pain: avoidance and endurance matter
ConclusionsThe results of the present study suggest that athletes and non ‐athletes with LBP differ regarding behavioural avoidance, but overall, differences regarding pain responses are marginal. FAR and ER are both reported in athletes and non‐athletes and contribute to disability in both groups.This article is protected by copyright. All rights reserved. (Source: European Journal of Pain)
Source: European Journal of Pain - June 20, 2019 Category: Anesthesiology Authors: H Gajsar, C Titze, C Levenig, M Kellmann, J Heidari, J Kleinert, A C Rusu, M I Hasenbring Tags: Original Article Source Type: research

The European epidemic: Pain prevalence and socioeconomic inequalities in pain across 19 European countries
ConclusionsFuture strategies to reduce the burden of pain should acknowledge and consider the associated socioeconomic inequalities of pain to ensure the “pain gap” does not widen.SignificanceThis is a pan European study that has explored socioeconomic inequalities in pain. Across Europe, pain is more prevalent in people of lower socioeconomic position; these pain inequalities were most significant for hand/arm pain, and least significant for back/neck pain. (Source: European Journal of Pain)
Source: European Journal of Pain - June 18, 2019 Category: Anesthesiology Authors: Adam Todd, Courtney L. McNamara, Mirza Balaj, Tim Huijts, Nasima Akhter, Katie Thomson, Adetayo Kasim, Terje A. Eikemo, Clare Bambra Tags: ORIGINAL ARTICLE Source Type: research

Masseter corticomotor excitability is decreased after intramuscular administration of nerve growth factor
AbstractBackgroundQuantification of motor ‐evoked potentials (MEPs) can contribute to better elucidate the central modulation of motor pathways in response to nociceptive inputs. The primary aim of this study was to assess the modulatory effects of nerve growth factor (NGF) injection on masseter corticomotor excitability.MethodsThe healthy participants of this randomized, double blind placebo ‐controlled experiment were assigned to have injected into the right masseter muscle either NGF (n=25) or isotonic saline (IS, n=17). The following variables were assessed at baseline and 48 hours after the injection: right masset...
Source: European Journal of Pain - June 13, 2019 Category: Anesthesiology Authors: Y. M. Costa, F. G. Exposto, M. Kothari, E. E. Castrillon, P. C. R. Conti, L. R. Bonjardim, P. Svensson Tags: Original Article Source Type: research

Associations between pain thresholds for heat, cold and pressure, and Pain Sensitivity Questionnaire (PSQ) scores in healthy women and in women with persistent pelvic pain
ConclusionsThe PSQ score was significantly higher in pelvic pain patients, and correlations between QSTs and the PSQ were only found for patients.This article is protected by copyright. All rights reserved. (Source: European Journal of Pain)
Source: European Journal of Pain - June 13, 2019 Category: Anesthesiology Authors: Hanna Grundstr öm, Britt Larsson, Lars Arendt‐Nielsen, Björn Gerdle, Preben Kjølhede Tags: Original Article Source Type: research

Weight management and musculoskeletal pain: Does sleep mediate the connection?
This article is protected by copyright. All rights reserved. (Source: European Journal of Pain)
Source: European Journal of Pain - June 13, 2019 Category: Anesthesiology Authors: Cristina Frange, Maria Fernanda Naufel, Fernando Morgadinho Santos Coelho Tags: Letter to the Editor Source Type: research

An internet ‐delivered cognitive behavioural therapy pain management programme for spinal cord injury pain: A randomized controlled trial
This study examines such an approach on quality of lie (QoL), pain, mood and sleep.MethodsAdults with SCI pain (>3  months) were recruited and randomly assigned to the intervention or control group. The intervention comprised a six module CBT‐PMP delivered once weekly. A blinded assessor determined changes in self‐reported outcome measures post‐intervention and at 3 months. Linear mixed models and effect sizes based on changes between groups were reported. Significance was setp 
Source: European Journal of Pain - June 13, 2019 Category: Anesthesiology Authors: Dearbhla Burke, Olive Lennon, Catherine Blake, Maeve Nolan, Sorcha Barry, Eimear Smith, Fiona Maye, John Lynch, Lorna O'Connor, Liz Maume, Sheena Cheyne, Sadb N í Ghiollain, Brona M. Fullen Tags: ORIGINAL ARTICLE Source Type: research

Visual attention to pain cues for impending touch versus impending pain: An eye tracking study
ConclusionsSupporting specific threat interpretation model premises, comparatively more threatening external pain cues for impending pain were characterized by gaze biases reflecting pronounced early attentional capture and subsequent prolonged vigilance. However, elevations in self ‐reported behavioural perseverance in spite of pain corresponded to an increased capacity to disengage from pain images that signalled potential pain.SignificanceGaze biases were assessed within a comparatively benign “impending touch” paradigm versus a higher threat, impending pain task. Early capture and maintenance of gaze towa...
Source: European Journal of Pain - June 13, 2019 Category: Anesthesiology Authors: Ying Ling, Zhou Yang, Todd Jackson Tags: ORIGINAL ARTICLE Source Type: research

Comment on the paper “Cognitive Functional Therapy in patients with Non Specific Chronic Low Back Pain”, by Vibe Fersum et al
This article is protected by copyright. All rights reserved. (Source: European Journal of Pain)
Source: European Journal of Pain - June 13, 2019 Category: Anesthesiology Authors: J. Fernandez, A.S. Ferreira, J. Castro, L.C.L. Correia, N. Meziat ‐Filho Tags: Letter to the Editor Source Type: research

Age Related Differences in the Acute Pain Facial Expression During Infancy
ConclusionsFacial expressions illustrating intense/moderate distress and sensory overload were prominent in the first 15 seconds at the 2 ‐, 4‐ and 6‐month vaccination. However, expressions showing regulation of distress occurred progressively earlier over 1 minute post‐needle in older infants, suggesting a significant shift in regulatory capacity of pain‐related distress occurs after 6‐months of age.SignificanceAn important developmental milestone was identified in infants ’ ability to regulate distress at 6 months. Supporting parents’ infant pain management is particularly critical in the first mo...
Source: European Journal of Pain - June 4, 2019 Category: Anesthesiology Authors: Monica C. O'Neill, Sara Ahola Kohut, Rebecca Pillai Riddell, Harriet Oster Tags: Original Article Source Type: research

Cornea nerve fiber state determines analgesic response to tapentadol in fibromyalgia patients without effective endogenous pain modulation
ConclusionsIn chronic pain patients with fibromyalgia, the increase in endogenous pain inhibition by tapentadol was translated into analgesia in patients with a normal CNFS. In those with abnormal CNFS, tapentadol treatment was without analgesic effect.This article is protected by copyright. All rights reserved. (Source: European Journal of Pain)
Source: European Journal of Pain - June 4, 2019 Category: Anesthesiology Authors: Tine van de Donk, Monique van Velzen, Albert Dahan, Marieke Niesters Tags: Original Article Source Type: research

S ándor Márai and his account of painful Guillain‐Barré syndrome
This article is protected by copyright. All rights reserved. (Source: European Journal of Pain)
Source: European Journal of Pain - June 4, 2019 Category: Anesthesiology Authors: M F Alamos, M Campero, R H Walker, M Miranda Tags: Letters to the Editor Source Type: research

Commentary on “Cognitive Functional Therapy in Patients with Non Specific Chronic Low Back Pain”
This article is protected by copyright. All rights reserved. (Source: European Journal of Pain)
Source: European Journal of Pain - June 4, 2019 Category: Anesthesiology Authors: Steven Z. George Tags: Commentary Source Type: research

Implementation of Patient ‐Reported Outcomes (PROMs) from specialist pain clinics in England and Wales: Experience from a nationwide study
ConclusionsPatients attending UK pain clinics report an extraordinarily poor quality of life and difficulty with understanding their condition. Problems with PROMs implementation included initial recruitment, follow ‐up response rates, classification systems and benchmarking. Successful implementation should include use of electronic data capture, feedback and focus on gradual improvement. To achieve this would require extended periods of funding.SignificanceNo nationwide evaluation of the effectiveness of specialist pain clinics had previously been attempted. Comparison of patient outcomes from services enables improvem...
Source: European Journal of Pain - May 31, 2019 Category: Anesthesiology Authors: Cathy M. Price, Amanda C. de C. Williams, Blair H. Smith, Alex Bottle Tags: ORIGINAL MANUSCRIPT Source Type: research

A diagnosis of rheumatoid arthritis, endometriosis or IBD is associated with later onset of fibromyalgia and chronic widespread pain
ConclusionsThis study shows that RA, endometriosis and IBD are all risk factors for later fibromyalgia and chronic widespread pain, consistent with a hypothesis of central sensitization as an effect of a painful underlying condition. (Source: European Journal of Pain)
Source: European Journal of Pain - May 27, 2019 Category: Anesthesiology Authors: F. Larrosa Pardo, E. Bondesson, M.E.C. Schelin, A. J öud Tags: ORIGINAL ARTICLE Source Type: research

The Role of Fatigue in Functional Outcomes for Youth with Chronic Pain
ConclusionsFindings suggest that fatigue is an important intervening factor for functional outcomes among youth with chronic pain. Targeting fatigue may be effective in optimizing school functioning and reducing the deleterious effects of depressive symptoms.This article is protected by copyright. All rights reserved. (Source: European Journal of Pain)
Source: European Journal of Pain - May 27, 2019 Category: Anesthesiology Authors: I.A. Yoon, J.A. Sturgeon, A.B. Feinstein, R.P. Bhandari Tags: ORIGINAL ARTICLE Source Type: research

Conditioning pain modulation reduces pain only during the first stimulation of the  temporal summation of pain paradigm in healthy participants
AbstractBackgroundPro ‐nociceptive and anti‐nociceptive mechanisms are commonly assessed in clinical and experimental pain studies, but their potential interaction is not well understood.ObjectivesInvestigate the effect of conditioning pain modulation (CPM) on temporal summation of pain (TSP).MethodsTwenty healthy participants underwent cuff algometry assessment on the lower legs to establish the pressure pain tolerance threshold (PTT). For the TSP assessment, ten stimuli at the level of the PTT were delivered by computerised cuff inflations (1 ‐s stimulation, 1‐s break) while participants rated pain intensity...
Source: European Journal of Pain - May 23, 2019 Category: Anesthesiology Authors: Sinead Holden, Kristian Kj ær Petersen, Lars Arendt‐Nielsen, Thomas Graven‐Nielsen Tags: ORIGINAL MANUSCRIPT Source Type: research

Effect of local infiltration with oxytocin on hemodynamic response to surgical incision and postoperative pain in patients having open laparoscopic surgery under general anesthesia
ConclusionsPreincisional subcutaneous OT administration reduced the hemodynamic response produced by the latter. Furthermore, OT also diminished postoperative pain.This article is protected by copyright. All rights reserved. (Source: European Journal of Pain)
Source: European Journal of Pain - May 22, 2019 Category: Anesthesiology Authors: Hector Zayas ‐González, Abimael González Hernández, Alfredo Manzano‐García, Donaciano Hernández‐Rivero, Marco Antonio García‐Cuevas, Juan Carlos Granados‐Mortera, Liliana Vaca‐Aguirre, Sergio Flores‐Fierro, Miguel Condés‐Lar Tags: Original Article Source Type: research

Visual Attention to Pain Cues for Impending Touch Versus Impending Pain: An Eye ‐Tracking Study
ConclusionsSupporting specific threat interpretation model premises, comparatively more threatening external pain cues for impending pain were characterized by gaze biases reflecting pronounced early attentional capture and subsequent prolonged vigilance. However, elevations in self ‐reported behavioral perseverance in spite of pain corresponded to an increased capacity to disengage from pain images that signaled potential pain.This article is protected by copyright. All rights reserved. (Source: European Journal of Pain)
Source: European Journal of Pain - May 21, 2019 Category: Anesthesiology Authors: Ying Ling, Zhou Yang, Todd Jackson Tags: Original Article Source Type: research

Predictors of treatment outcome in children with medically unexplained pain seeking primary care: A prospective cohort study
AbstractBackgroundMedically unexplained pain in children and adolescents is a common and increasing health care problem. Primary care is usually the first point of contact for these patients. It is the overall objective of this study to investigate treatment outcome of medically unexplained pain in pediatric primary care and to identify predictors of treatment failure.MethodIn a prospective observational cohort study with three assessments over six months, N=266 children (6 to 17 years) presenting to pediatric primary care due to medically unexplained pain were included. The primary outcome is treatment failure after 6 mon...
Source: European Journal of Pain - May 21, 2019 Category: Anesthesiology Authors: Julia Wager, Katharina Szybalski, Sabrina Schenk, Michael Frosch, Boris Zernikow Tags: Original Article Source Type: research

The Relation of Self ‐Compassion to Functioning among Adults with Chronic Pain
AbstractPrevious research has shown that self ‐compassion is associated with improved functioning and health outcomes among multiple chronic illnesses. However, the role of self‐compassion in chronic pain‐related functioning is understudied. The present study sought to understand the association between self‐compassion and important mea sures of functioning within a sample of patients with chronic pain. Treatment‐seeking individuals (N= 343 with chronic pain) that were mostly White (97.9%) and female (71%) completed a battery of assessments that included the Self‐Compassion Scale (SCS), as well as measures of p...
Source: European Journal of Pain - May 21, 2019 Category: Anesthesiology Authors: Karlyn A. Edwards, Melissa Pielech, Jayne Hickman, Julie Ashworth, Gail Sowden, Kevin E. Vowles Tags: Original Article Source Type: research

The effectiveness of self ‐management interventions in adults with chronic orofacial pain: A systematic review, Meta‐analysis and Meta‐regression
European Journal of Pain, EarlyView. (Source: European Journal of Pain)
Source: European Journal of Pain - May 20, 2019 Category: Anesthesiology Authors: Maite Ferrando Garcia Tags: COMMENTARY Source Type: research

Pain and Posttraumatic Stress Disorder in refugees who survived torture: The role of pain catastrophizing and trauma ‐related beliefs
ConclusionsNegative beliefs about pain and the trauma made small, but additive contributions to the relationship between pain and PTSD severity, after controlling for depression. Longitudinal studies with refugees, involving tests of more complex mutual maintenance models, are warranted.This article is protected by copyright. All rights reserved. (Source: European Journal of Pain)
Source: European Journal of Pain - May 16, 2019 Category: Anesthesiology Authors: L. Nordin, S. Perrin Tags: Original Article Source Type: research

Exercise ‐induced hypoalgesia is present in people with Parkinson’s disease: Two observational cross‐sectional studies
ConclusionsOverall, people with Parkinson ’s disease experienced an exercise‐induced hypoalgesia response similar to that of the control group, the extent of which did not vary between mild and moderate doses of aerobic exercise. Further research is warranted to investigate potential longer term benefits from exercise in the management of pain in this population.SignificanceIsometric and aerobic exercise reduces pain sensitivity in people with Parkinson ’s disease. As exercise is important for people with Parkinson’s disease, these results provide assurance that people with Parkinson’s disease and...
Source: European Journal of Pain - May 14, 2019 Category: Anesthesiology Authors: Vanessa Nguy, Benjamin K. Barry, Niamh Moloney, Leanne M. Hassett, Colleen G. Canning, Simon J. G. Lewis, Natalie E. Allen Tags: ORIGINAL ARTICLE Source Type: research

Cognitive functional therapy in patients with non ‐specific chronic low back pain—a randomized controlled trial 3‐year follow‐up
AbstractObjectivesThis randomized controlled trial investigated the efficacy of cognitive functional therapy (CFT) compared with manual therapy and exercise (MT ‐EX) for people with non‐specific chronic low back pain (NSCLBP) at 3‐year follow‐up.MethodsHundred and twenty ‐one patients were randomized to CFT (n = 62) or MT‐EX (n = 59). Three‐year data were available for 30 (48.4%) participants in the CFT group, and 33 (55.9%) participants in the MT‐EX group. The primary outcomes were disability (Oswestry disability Index [ODI]) and pain intensity (numerical rating scale) and secondary out...
Source: European Journal of Pain - May 14, 2019 Category: Anesthesiology Authors: Kjartan Vibe Fersum, Anne Smith, Alice Kv åle, Jan Sture Skouen, Peter O'Sullivan Tags: ORIGINAL ARTICLE Source Type: research

Associations of Co ‐occurring Psychosocial and Lifestyle Factors with Multisite Musculoskeletal Pain during Late Adolescence – A birth Cohort Study
ConclusionsAdolescents with psychosocial difficulties and/or several adverse health behaviours were at an increased risk of recurrent multisite MS pain, which emphasizes the importance of simultaneously studying multiple rather than single factors. The identification of risk groups may help more accurately target preventive interventions.SignificanceThis study found subgroups of adolescents at risk of recurrent multisite musculoskeletal pain during late adolescence. The accumulation of multiple adverse behaviours is likely to provide new perspectives for understanding the multidimensional nature of multiple MS pains.This a...
Source: European Journal of Pain - May 9, 2019 Category: Anesthesiology Authors: Eveliina Heikkala, Markus Paananen, Simo Taimela, Juha Auvinen, Jaro Karppinen Tags: Original Article Source Type: research

Unveiling the Relationship Between Central Parkinsonian Pain and Motor Symptoms in Parkinson's Disease
ConclusionsPD patients with central parkinsonian pain have some distinctive demographic and clinical features, including lower levodopa responsiveness of motor appendicular/limb symptoms to levodopa, associated with greater responsiveness of pain symptoms to these same medications. These findings suggest the need for a more integrated approach to motor and non ‐motor symptoms in these patients’ clinical care.This article is protected by copyright. All rights reserved. (Source: European Journal of Pain)
Source: European Journal of Pain - May 9, 2019 Category: Anesthesiology Authors: N. Vila ‐Chã, S. Cavaco, A. Mendes, A. Gonçalves, I. Moreira, J. Fernandes, J. Damásio, L F Azevedo, J Castro‐Lopes Tags: Original Article Source Type: research

The relationships between worry, happiness and pain catastrophizing in the experience of acute pain
ConclusionsThe findings demonstrate that pain intensity, worry about pain and pain catastrophizing are all sensitive to changes in mood. The results have potential clinical implications.SignificanceThe current study shows that manipulation ‐induced changes in pain‐related worry, pain catastrophizing, and affect have direct effects on the experience of acute pain. More broadly, the overlap of these three variables provides with anxiety and mood disorders offers the promise of new vistas for research and treatment of pain conditions by assessing and targeting the cognitions and behaviors that are common to worry and cata...
Source: European Journal of Pain - May 9, 2019 Category: Anesthesiology Authors: John C. Lefebvre, Mark P. Jensen Tags: ORIGINAL ARTICLE Source Type: research

Discharged and dismissed: A qualitative study with back pain patients discharged without treatment from orthopaedic consultations
ConclusionEffective communication with patients attending spinal orthopaedic care settings is important, especially when no active treatment is being offered.This article is protected by copyright. All rights reserved. (Source: European Journal of Pain)
Source: European Journal of Pain - May 9, 2019 Category: Anesthesiology Authors: Kathrin Braeuninger ‐Weimer, Naffis Anjarwalla, Tamar Pincus Tags: Original Article Source Type: research

Combination pharmacotherapy for tackling descending controls and central sensitization
European Journal of Pain, EarlyView. (Source: European Journal of Pain)
Source: European Journal of Pain - April 30, 2019 Category: Anesthesiology Authors: Rolf ‐Detlef Treede, Sigrid Schuh‐Hofer, Walter Magerl, Carmen La Porta, Anke Tappe‐Theodor Tags: COMMENTARY Source Type: research

Conditioning pain modulation reduces pain only during the first stmimulation of temporal summation of pain paradigm in healthy participants
AbstractBackgroundPro ‐nociceptive and anti‐nociceptive mechanisms are commonly assessed in clinical and experimental pain studies, while their potential interaction is not well understood.ObjectivesInvestigate the effect of conditioning pain modulation (CPM) on temporal summation of pain (TSP).MethodsTwenty healthy participants underwent cuff algometry assessment on the lower legs to establish the pressure pain tolerance threshold (PTT). For the TSP assessment, ten stimuli at the level of the PTT were delivered by computerised cuff inflations (1 ‐s stimulation, 1‐s break) while participants rated pain intensity on...
Source: European Journal of Pain - April 30, 2019 Category: Anesthesiology Authors: S Holden, K K Petersen, L Arendt ‐Nielsen, T Graven‐Nielsen Tags: Original Article Source Type: research

The Europain Epidemic: pain prevalence and socioeconomic inequalities in pain across 19 European countries
ConclusionsFuture strategies to reduce the burden of pain should acknowledge and consider the associated socioeconomic inequalities of pain to ensure the ‘pain gap’ does not widen.This article is protected by copyright. All rights reserved. (Source: European Journal of Pain)
Source: European Journal of Pain - April 30, 2019 Category: Anesthesiology Authors: Adam Todd, Courtney L. McNamara, Mirza Balaj, Tim Huijts, Nasima Akhter, Katie Thomson, Adetayo Kasim, Terje A Eikemo, Clare Bambra Tags: Original Article Source Type: research