Comment on ‘The importance of context (placebo effects) in conservative interventions for musculoskeletal pain: A systematic review and meta‐analysis of randomized controlled trials’ by Saueressig et al.
(Source: European Journal of Pain)
Source: European Journal of Pain - January 22, 2024 Category: Anesthesiology Authors: Yasmin Ezzatvar, David Poulter, Enrique Lluch ‐Girbés, Lirios Dueñas, Mercè Balasch‐Bernat, Giacomo Rossettini Tags: LETTER TO THE EDITOR Source Type: research

Assessment of the concordance between DN4 scores performed by the patient (self ‐assessment) or by the physician (hetero‐assessment) to detect subacute neuropathic postoperative pain
ConclusionsOur results suggest that after a short training, a na ïve patient is capable of recognizing and diagnosing symptoms of neuropathic pain.SignificanceOur results suggest that self-assessment, carried out after brief training and using a simple tool, provides results comparable to those obtained by a specialist physician to diagnose symptoms of neuropathic pain. If the results of the current study are confirmed on a larger scale, self-assessment will help improve access to specialized chronic pain care by better orienting patients and opening up access to teleconsultations. (Source: European Journal of Pain)
Source: European Journal of Pain - January 20, 2024 Category: Anesthesiology Authors: Fr édéric Adam, Gilles Chatellier, Pascal Alfonsi Tags: ORIGINAL ARTICLE Source Type: research

The costs of chronic pain —Long‐term estimates
ConclusionInsights from this study can provide a greater understanding of the extent of healthcare use and productivity loss by those with chronic pain and serve as an important basis for improvements in rehabilitation and quality of care, and the education of the public on the burden of chronic pain.SignificanceThis was the first study to estimate the economic burden associated with chronic pain in the general population using linked individual-level administrative data and self-reported survey answers. We provide calculations showing that annual costs of chronic pain may be as high as €12 billion or 4% of GDP. Findings...
Source: European Journal of Pain - January 13, 2024 Category: Anesthesiology Authors: Audun Stubhaug, Johan Liseth Hansen, Sara Hallberg, Anders Gustavsson, Anne Elise Eggen, Christopher Sivert Nielsen Tags: ORIGINAL ARTICLE Source Type: research

Neighbourhood socioeconomic status and pain among older adults —A cross‐sectional study
ConclusionGiven the high prevalence of pain across populations, interventions targeting geographic areas (such as those in the current study) in combination with individual risk factors could be effective to reduce the burden of pain at the population level.SignificanceThose who reside in neighbourhoods with low SES may have higher risks of pain due to a lack of health-promoting resources as well as psychological stress. Further studies identifying the specific mechanisms behind the association between neighbourhood SES and pain would be useful in order to develop effective interventions. (Source: European Journal of Pain)
Source: European Journal of Pain - January 12, 2024 Category: Anesthesiology Authors: Kenta Okuyama, Sven ‐Erik Johansson, Kristina Sundquist Tags: ORIGINAL ARTICLE Source Type: research

Anxiety, history of childhood adversity, and experiencing chronic pain in adulthood: A systematic literature review and meta ‐analysis
ConclusionThe results of the SLR and meta-analysis indicated that ACEs and anxiety influence chronic pain experience in adults. Given the relationship between ACEs and anxiety, there would be value in exploring this as a potential mediator in future studies.SignificanceThere was an unmet need to summarize the existing literature on the relationship between ACEs and anxiety on chronic pain experience in adults and the association between ACEs and anxiety. The results of this systematic review and meta-analysis indicated that both ACEs and anxiety influenced chronic pain experience in adults and helped to inform the diverse ...
Source: European Journal of Pain - January 9, 2024 Category: Anesthesiology Authors: Danielle E. Dalechek, Line Caes, Gwenne McIntosh, Anna C. Whittaker Tags: ORIGINAL ARTICLE Source Type: research

Psychological profiles and prescription opioid misuse, craving, and withdrawal in people with chronic pain
ConclusionsThese results support that impulsivity, anxiety sensitivity, and pain acceptance are useful constructs to identify subgroups of people with chronic pain according to their level of prescription opioid misuse, craving, and withdrawal. The results of this study may help in selecting the early intervention most suitable for each of the identified profiles.SignificanceThe psychological profile of individuals with chronic pain, prescription opioid misuse, craving, and withdrawal is characterized by fearing anxiety-related symptoms due to the catastrophic interpretation of such symptoms and reacting impulsively to neg...
Source: European Journal of Pain - January 8, 2024 Category: Anesthesiology Authors: R. Esteve, V. Barrado ‐Moreno, C. Ramírez‐Maestre, E. R. Serrano‐Ibáñez, R. de la Vega, G. T. Ruiz‐Párraga, G. Sainero‐Tirado, M. Fernández Baena, M. Jensen, A. E. López‐Martínez Tags: ORIGINAL ARTICLE Source Type: research

Movement ‐evoked pain is not associated with pain at rest or physical function in knee osteoarthritis
ConclusionMovement-evoked pain is neither related to pain at rest nor to functional performance in subjects affected by knee osteoarthritis. The results from our study suggest that MEP and pain at rest measure and refer to different constructs in knee osteoarthritis. The implementation of MEP as an outcome in exercise-therapy could enhance the tracking of results, as well as the development of tailored interventions under different conditions.SignificanceThis research elucidates the relevance of MEP, recently defined as ‘pain during walking’, through the analysis of its association with PAR and with functional performa...
Source: European Journal of Pain - January 8, 2024 Category: Anesthesiology Authors: Jos é Antonio Lozano‐Meca, Mariano Gacto‐Sánchez, Joaquina Montilla‐Herrador Tags: ORIGINAL ARTICLE Source Type: research

Comment on: Virtual reality increases pressure pain threshold and lowers anxiety in children compared with control and non ‐immersive control—A randomized, crossover trial
(Source: European Journal of Pain)
Source: European Journal of Pain - January 8, 2024 Category: Anesthesiology Authors: Benyamin Alam, Mohammad Zakariya Mahmood, Husnain Akhtar, Mohammed Adnaan Munshi Tags: LETTER TO THE EDITOR Source Type: research

Issue Information
(Source: European Journal of Pain)
Source: European Journal of Pain - January 8, 2024 Category: Anesthesiology Tags: ISSUE INFORMATION Source Type: research

Mendelian randomization study of lipid metabolism characteristics and migraine risk
ConclusionsThere is a relationship between lipid metabolism characteristics and migraine risk.SignificanceBased on the genome-wide association summary data, single-nucleotide polymorphisms (SNPs) related to high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), non-high-density lipoprotein cholesterol (non-HDL-C), total cholesterol (TC), or triglycerides (TG) level were not associated with risk of migraine, migraine with aura (MA) or migraine without aura (MO). However, genotypes ofHMGCR related to higher LDL-C levels have shown an increased risk on migraine and MA. And genotypes ofAPOB ...
Source: European Journal of Pain - January 7, 2024 Category: Anesthesiology Authors: Peiwei Hong, Lin Han, Yang Wan Tags: ORIGINAL ARTICLE Source Type: research

Author's reply to the comment by Min Cheol Chang and Mathieu Boudier ‐Revéret
(Source: European Journal of Pain)
Source: European Journal of Pain - January 4, 2024 Category: Anesthesiology Authors: Peter R. Kamerman Tags: LETTER TO THE EDITOR Source Type: research

Exploring biomarkers in trigeminal neuralgia patients operated with microvascular decompression: A comparison with multiple sclerosis patients and non ‐neurological controls
ConclusionsWe conclude that TN patients showed increased serum and CSF levels of specific proteins and that successful surgery normalizes these protein levels, highlighting its potential as an effective treatment. However, the similarity between MS and controls challenges the idea of shared pathophysiology with TN, suggesting distinct underlying mechanisms in these conditions.SignificanceThis study advances our understanding of trigeminal neuralgia (TN) and its association with multiple sclerosis (MS). By analysing 92 protein biomarkers, we identified distinctive molecular profiles in TN patients, shedding light on potenti...
Source: European Journal of Pain - December 30, 2023 Category: Anesthesiology Authors: Muataz S. Lafta, Aleksandr V. Sokolov, Anne ‐Marie Landtblom, Hans Ericson, Helgi B. Schiöth, Sami Abu Hamdeh Tags: ORIGINAL ARTICLE Source Type: research

Fatigue can influence the development of late ‐onset pain in post‐COVID‐19 syndrome: An observational study
ConclusionsAlmost one out of three patients hospitalized for COVID-19 developed pain 1  year later, and fatigue seems responsible for chronicity. An overlapping of conditions may explain late-onset post-COVID-19 pain, and a comprehensive approach must be considered for patient management.SignificanceLate-onset pain is frequent in post-COVID-19 syndrome and an overlapping of different mechanisms seems to be responsible for its development. Among many predisposing factors, fatigue in the months before seems to be one of the primary causes of pain one year following infection and its management may help to identify new stra...
Source: European Journal of Pain - December 29, 2023 Category: Anesthesiology Authors: A. Baroni, G. Fregna, N. Lamberti, F. Manfredini, S. Straudi Tags: ORIGINAL ARTICLE Source Type: research

Authors' reply to the comment by Alam et  al.
(Source: European Journal of Pain)
Source: European Journal of Pain - December 28, 2023 Category: Anesthesiology Authors: L. Kjelgaard  Pedersen, L. Y. V. Fisker, J. D. Rölfing, P. Ahlburg, M. Veien, L. Vase, B. Møller‐Madsen Tags: COMMENTARY Source Type: research

Social cues influence perception of others' pain
ConclusionsTogether, these studies reveal that judgements of others' pain are robustly modulated by information about others' opinions. Future research could test the prevalence and strength of such effects in clinical settings.SignificanceThe present study shows that even arbitrary opinions of other raters influence the perception of others' pain. This finding adds new insight into the growing evidence of social and cultural biases in pain estimation. (Source: European Journal of Pain)
Source: European Journal of Pain - December 27, 2023 Category: Anesthesiology Authors: Lanlan Zhang, Tor D. Wager, Leonie Koban Tags: ORIGINAL ARTICLE Source Type: research