Psychological profiles and prescription opioid misuse, craving, and withdrawal in people with chronic pain
ConclusionsThese results support that impulsivity, anxiety sensitivity, and pain acceptance are useful constructs to identify subgroups of people with chronic pain according to their level of prescription opioid misuse, craving, and withdrawal. The results of this study may help in selecting the early intervention most suitable for each of the identified profiles.SignificanceThe psychological profile of individuals with chronic pain, prescription opioid misuse, craving, and withdrawal is characterized by fearing anxiety-related symptoms due to the catastrophic interpretation of such symptoms and reacting impulsively to neg...
Source: European Journal of Pain - January 8, 2024 Category: Anesthesiology Authors: R. Esteve,
V. Barrado ‐Moreno,
C. Ramírez‐Maestre,
E. R. Serrano‐Ibáñez,
R. de la Vega,
G. T. Ruiz‐Párraga,
G. Sainero‐Tirado,
M. Fernández Baena,
M. Jensen,
A. E. López‐Martínez Tags: ORIGINAL ARTICLE Source Type: research
Movement ‐evoked pain is not associated with pain at rest or physical function in knee osteoarthritis
ConclusionMovement-evoked pain is neither related to pain at rest nor to functional performance in subjects affected by knee osteoarthritis. The results from our study suggest that MEP and pain at rest measure and refer to different constructs in knee osteoarthritis. The implementation of MEP as an outcome in exercise-therapy could enhance the tracking of results, as well as the development of tailored interventions under different conditions.SignificanceThis research elucidates the relevance of MEP, recently defined as ‘pain during walking’, through the analysis of its association with PAR and with functional performa...
Source: European Journal of Pain - January 8, 2024 Category: Anesthesiology Authors: Jos é Antonio Lozano‐Meca,
Mariano Gacto‐Sánchez,
Joaquina Montilla‐Herrador Tags: ORIGINAL ARTICLE Source Type: research
Comment on: Virtual reality increases pressure pain threshold and lowers anxiety in children compared with control and non ‐immersive control—A randomized, crossover trial
(Source: European Journal of Pain)
Source: European Journal of Pain - January 8, 2024 Category: Anesthesiology Authors: Benyamin Alam,
Mohammad Zakariya Mahmood,
Husnain Akhtar,
Mohammed Adnaan Munshi Tags: LETTER TO THE EDITOR Source Type: research
Issue Information
(Source: European Journal of Pain)
Source: European Journal of Pain - January 8, 2024 Category: Anesthesiology Tags: ISSUE INFORMATION Source Type: research
Mendelian randomization study of lipid metabolism characteristics and migraine risk
ConclusionsThere is a relationship between lipid metabolism characteristics and migraine risk.SignificanceBased on the genome-wide association summary data, single-nucleotide polymorphisms (SNPs) related to high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), non-high-density lipoprotein cholesterol (non-HDL-C), total cholesterol (TC), or triglycerides (TG) level were not associated with risk of migraine, migraine with aura (MA) or migraine without aura (MO). However, genotypes ofHMGCR related to higher LDL-C levels have shown an increased risk on migraine and MA. And genotypes ofAPOB ...
Source: European Journal of Pain - January 7, 2024 Category: Anesthesiology Authors: Peiwei Hong,
Lin Han,
Yang Wan Tags: ORIGINAL ARTICLE Source Type: research
Author's reply to the comment by Min Cheol Chang and Mathieu Boudier ‐Revéret
(Source: European Journal of Pain)
Source: European Journal of Pain - January 4, 2024 Category: Anesthesiology Authors: Peter R. Kamerman Tags: LETTER TO THE EDITOR Source Type: research
Exploring biomarkers in trigeminal neuralgia patients operated with microvascular decompression: A comparison with multiple sclerosis patients and non ‐neurological controls
ConclusionsWe conclude that TN patients showed increased serum and CSF levels of specific proteins and that successful surgery normalizes these protein levels, highlighting its potential as an effective treatment. However, the similarity between MS and controls challenges the idea of shared pathophysiology with TN, suggesting distinct underlying mechanisms in these conditions.SignificanceThis study advances our understanding of trigeminal neuralgia (TN) and its association with multiple sclerosis (MS). By analysing 92 protein biomarkers, we identified distinctive molecular profiles in TN patients, shedding light on potenti...
Source: European Journal of Pain - December 30, 2023 Category: Anesthesiology Authors: Muataz S. Lafta,
Aleksandr V. Sokolov,
Anne ‐Marie Landtblom,
Hans Ericson,
Helgi B. Schiöth,
Sami Abu Hamdeh Tags: ORIGINAL ARTICLE Source Type: research
Fatigue can influence the development of late ‐onset pain in post‐COVID‐19 syndrome: An observational study
ConclusionsAlmost one out of three patients hospitalized for COVID-19 developed pain 1 year later, and fatigue seems responsible for chronicity. An overlapping of conditions may explain late-onset post-COVID-19 pain, and a comprehensive approach must be considered for patient management.SignificanceLate-onset pain is frequent in post-COVID-19 syndrome and an overlapping of different mechanisms seems to be responsible for its development. Among many predisposing factors, fatigue in the months before seems to be one of the primary causes of pain one year following infection and its management may help to identify new stra...
Source: European Journal of Pain - December 29, 2023 Category: Anesthesiology Authors: A. Baroni,
G. Fregna,
N. Lamberti,
F. Manfredini,
S. Straudi Tags: ORIGINAL ARTICLE Source Type: research
Authors' reply to the comment by Alam et al.
(Source: European Journal of Pain)
Source: European Journal of Pain - December 28, 2023 Category: Anesthesiology Authors: L. Kjelgaard Pedersen,
L. Y. V. Fisker,
J. D. Rölfing,
P. Ahlburg,
M. Veien,
L. Vase,
B. Møller‐Madsen Tags: COMMENTARY Source Type: research
Social cues influence perception of others' pain
ConclusionsTogether, these studies reveal that judgements of others' pain are robustly modulated by information about others' opinions. Future research could test the prevalence and strength of such effects in clinical settings.SignificanceThe present study shows that even arbitrary opinions of other raters influence the perception of others' pain. This finding adds new insight into the growing evidence of social and cultural biases in pain estimation. (Source: European Journal of Pain)
Source: European Journal of Pain - December 27, 2023 Category: Anesthesiology Authors: Lanlan Zhang,
Tor D. Wager,
Leonie Koban Tags: ORIGINAL ARTICLE Source Type: research
The importance of context (placebo effects) in conservative interventions for musculoskeletal pain: A systematic review and meta ‐analysis of randomized controlled trials
ConclusionThe study found that the contextual effect of non-pharmacological conservative interventions for musculoskeletal conditions is likely to be small. However, given the known effect sizes of recommended evidence-based treatments for musculoskeletal conditions, it may still contribute an important component.SignificanceContextual effects of non-pharmacological conservative interventions for musculoskeletal conditions are likely to be small for a broad range of patient-reported outcomes (pain intensity, physical function, quality of life, global rating of change and depression). Contextual effects are unlikely, in iso...
Source: European Journal of Pain - December 21, 2023 Category: Anesthesiology Authors: Tobias Saueressig,
Patrick J. Owen,
Hugo Pedder,
Scott Tagliaferri,
Svenja Kaczorowski,
Adina Altrichter,
Antonia Richard,
Clint T. Miller,
Lars Donath,
Daniel L. Belavy Tags: REVIEW ARTICLE Source Type: research
Change in pain expectations but no open ‐label placebo analgesia: An experimental study using the heat pain paradigm
ConclusionsOur study suggests that evoking positive treatment expectations is not sufficient to elicit an OLP response. Possibly, the magnitude of expectations change in this study was not powerful enough to evoke an OLP effect. Additionally, it is possible that OLP effects in pain are unrelated to positive treatment expectations. The failure of OLP in our study is in contrast to a number of previous studies examining the effects of OLP in experimental and clinical pain.SignificanceThis study provides evidence that positive treatment expectations are not sufficient to evoke an open-label placebo effect in a standardized he...
Source: European Journal of Pain - December 19, 2023 Category: Anesthesiology Authors: Thilo Friehs,
Christopher Milde,
Julia Anna Glombiewski,
Tobias Kube Tags: ORIGINAL ARTICLE Source Type: research
Long ‐term postoperative opioid use in orthopaedic patients
ConclusionThe prevalence of long-term postoperative opioid use was 12.5%; one in thirty patients became a new long-term opioid user. Pre-operative opioid use and affected body region were predictive for long-term opioid use. These findings, together with the observation that long-term opioid users want to taper opioids, emphasize the relevance of prevention, recognition and tapering support in the perioperative setting.Level of EvidenceLevel II.SignificanceShort-term opioid use can unintentionally progress to long-term opioid use. The prevalence of long-term opioid use after orthopaedic surgery varies widely and is mostly ...
Source: European Journal of Pain - December 18, 2023 Category: Anesthesiology Authors: Eward J. Melis,
Johanna E. Vriezekolk,
Julian C. C. van der Laan,
Jos é M. H. Smolders,
Bart J. F. van den Bemt,
Maaike G. E. Fenten Tags: ORIGINAL ARTICLE Source Type: research
Autonomic nervous system function assessed by heart rate variability and the presence of symptoms affecting activities of daily living in community ‐dwelling residents with chronic pain: The Hisayama Study
ConclusionsDecreased heart rate variability was associated with the presence of symptoms affecting ADL among individuals with chronic pain in a Japanese community.SignificanceDecrease in heart rate variability was associated with the presence of symptoms affecting ADL among individuals with chronic pain in a Japanese community. This article could help scientists understand the significance of autonomic nervous system dysfunction in the pathology of chronic pain. Approaches that target autonomic nervous system dysfunction may be an option to relieve or prevent symptoms affecting ADL for chronic pain sufferers. (Source: Euro...
Source: European Journal of Pain - December 17, 2023 Category: Anesthesiology Authors: Yuri Nakamura,
Mao Shibata,
Yukiko Morisaki,
Naoki Hirabayashi,
Mayu Higashioka,
Jun Hata,
Masako Hosoi,
Nobuyuki Sudo,
Ken Yamaura,
Toshiharu Ninomiya Tags: ORIGINAL ARTICLE Source Type: research
A two ‐component model of hair cortisol concentration in fibromyalgia: Independent effects of pain chronicity and severity
ConclusionsThese results support the existence of a dysfunction in the regulation of the HPA axis in FM and its possible contribution to chronic pain development.SignificanceThis is the first study to assess hair cortisol concentrations in a specific sample of patients with fibromyalgia (FM). This method is especially useful for the assessment of long-term regular cortisol excretion. Results showed a two-component model for explaining cortisol levels: disease chronicity, with a negative effect, and symptom severity, with a positive effect. This suggests that severe pain/stress evokes higher cortisol levels at earlier stage...
Source: European Journal of Pain - December 16, 2023 Category: Anesthesiology Authors: G. A. Reyes del Paso,
A. Garcia‐Hernandez,
A. M. Contreras‐Merino,
C. M. Galvez‐Sánchez,
P. de la Coba,
C. I. Montoro,
D. M. Davydov Tags: ORIGINAL ARTICLE Source Type: research
