Chronic pain is associated with less grey matter volume in the anterior cingulum, anterior and posterior insula and hippocampus across three different chronic pain conditions
ConclusionsChronic pain across three different pain conditions was characterized by less GMV in brain regions consistently described for different chronic pain conditions before. Less GMV in the left hippocampus mediated by experienced stress during the last year might be related to altered pain learning mechanisms in chronic pain patients.SignificanceGrey matter reorganization could serve as a diagnostic biomarker for chronic pain. In a large cohort, we here replicated findings of less grey matter volume across three pain conditions in the left anterior and posterior insula, anterior cingulate and left hippocampus. Less h...
Source: European Journal of Pain - June 27, 2023 Category: Anesthesiology Authors: Nicola Neumann,
Martin Domin,
Carsten ‐Oliver Schmidt,
Martin Lotze Tags: ORIGINAL ARTICLE Source Type: research
Cognitive ‐affective changes mediate the mindfulness‐based intervention effect on endometriosis‐related pain and mental health: A path analysis approach
ConclusionsOur findings showed that bMBI impacts pain through changes in pain-related cognitive-affective factors. bMBI can improve QoL-MH by multiple pathways, including but not limited to pain reduction, highlighting the independent potential of improvement in affect to restore mental health in endometriosis.SignificanceBrief mindfulness-based intervention improves endometriosis pain through pain-related cognitive-affective factors and quality of life mental health via pain and affect changes unrelated to pain. (Source: European Journal of Pain)
Source: European Journal of Pain - June 27, 2023 Category: Anesthesiology Authors: Marcelo de Fran ça Moreira,
Olga Lucia Gamboa,
Marco Aurelio Pinho Oliveira Tags: ORIGINAL ARTICLE Source Type: research
Influence of skin type and laser wavelength on laser ‐evoked potentials
ConclusionsThis study shows that LEP elicitation depends on the combination of laser penetrance and skin type. Low penetrance stimuli, from a CO2 laser, elicited significantly lower LEPs and perceived intensities in the palm.SignificanceThis study showed that the elicitation of laser-evoked potentials in healthy humans greatly depends on the combination of laser stimulator type and skin type. It was shown that high penetrance laser stimuli are capable of eliciting responses in both hairy and glabrous skin, whereas low penetrance stimuli barely elicited responses from the glabrous skin. Computational modelling was used to d...
Source: European Journal of Pain - June 26, 2023 Category: Anesthesiology Authors: Ken Steffen Frahm,
Sabata Gervasio,
Federico Arguissain,
Andr é Mouraux Tags: ORIGINAL ARTICLE Source Type: research
Sex differences in lifetime prevalence of low back pain: A multinational study of opposite ‐sex twin pairs
ConclusionsWe found no evidence of the association between sex and LBP in our merged sample. Between-population differences (i.e. cultural background or health system characteristics) are likely to be major factors leading to variation in the sex association with LBP when familial factors are accounted for.SignificanceOur study of adult opposite-sex twin pairs found no evidence of an association between female sex and lifetime prevalence of low back pain after controlling for familial factors in the merged sample from Australia, Spain and USA, contrary to findings from previous studies of unrelated individuals. Our finding...
Source: European Journal of Pain - June 26, 2023 Category: Anesthesiology Authors: Lucas Calais ‐Ferreira,
Daniel Pozzobon,
Marina B. Pinheiro,
Fiona M. Blyth,
Juan R. Ordoñana,
Glen E. Duncan,
John L. Hopper,
Paulo H. Ferreira,
Manuela L. Ferreira Tags: ORIGINAL ARTICLE Source Type: research
Where does it hurt? Small area estimates and inequality in the prevalence of chronic pain
ConclusionsPrevalence of chronic and high-impact chronic pain in adults aged 35+ varies substantially between neighbourhoods within local authorities. Further insight into small-area level variation will help target resources to improve the management and prevention of chronic and high-impact chronic pain to reduce the impact on individuals, communities, workplaces, services and the economy.SignificancePost-stratified multilevel model predictions can produce small-area estimates of pain prevalence and impact. The evidence of substantial variation indicates a need to collect local-level data on pain and its impact to unders...
Source: European Journal of Pain - June 22, 2023 Category: Anesthesiology Authors: Marty Lynch,
George Peat,
Kelvin Jordan,
Dahai Yu,
Ross Wilkie Tags: ORIGINAL ARTICLE Source Type: research
Communication of pain intensity and unpleasantness through magnitude ratings: Influence of scale type, but not gender of the participant
ConclusionsThese findings confirm differences in rating scale usage; however, the different usage might not contribute significantly to gender differences in pain.SignificanceThere are differences in the usage of rating scales in which ratings for auditory, visual and noxious somatosensory stimuli are higher with NRS compared to VAS. Choosing a rating scale for research or clinical use should take this different item functioning into account. (Source: European Journal of Pain)
Source: European Journal of Pain - June 22, 2023 Category: Anesthesiology Authors: Hadas Nahman ‐Averbuch,
Cassidy Hughes,
Marie‐Eve Hoeppli,
Kristina White,
James Peugh,
Eric Leon,
Christopher D. King,
Robert C. Coghill Tags: ORIGINAL ARTICLE Source Type: research
Task ‐dependent functional connectivity of pain is associated with the magnitude of placebo analgesia in pain‐free individuals
ConclusionsResults suggest that stronger expectancy-based placebo responses might be underpinned by greater FC among attentional and somatosensory regions.SignificanceThis article provides support and insight for task-dependent functional connectivity differences related to the magnitude of placebo analgesia. Our findings provide key support that the magnitude of expectation-based placebo response depends on the coupling of regions associated with somatosensory and attentional processing. (Source: European Journal of Pain)
Source: European Journal of Pain - June 22, 2023 Category: Anesthesiology Authors: Nicholas J. Bush,
Jeff Boissoneault,
Janelle Letzen,
Roland Staud,
Michael E. Robinson Tags: ORIGINAL ARTICLE Source Type: research
Issue Information
(Source: European Journal of Pain)
Source: European Journal of Pain - June 12, 2023 Category: Anesthesiology Tags: ISSUE INFORMATION Source Type: research
Comparison between pupillometry and numeric pain rating scale for pain assessments in communicating adult patients in the emergency department
ConclusionsPupillometry does not appear to be an effective tool to evaluate pain in the ED environment. Indeed, too many factors influencing the sympathetic system —and thus the dynamic pupillary measures—are not controllable in the ED.SignificancePupillometry does not appear to be an effective tool to evaluate pain in the ED environment.There are several possible explanations for these negative results. The factors influencing the sympathetic system —and thus the PD fluctuations—are controllable in the postoperative period but not in the ED (e.g. full bladder, hypothermia). In addition, numerous psychological phen...
Source: European Journal of Pain - June 12, 2023 Category: Anesthesiology Authors: Charles Gregoire,
David Charier,
Romane de Bergeyck,
André Mouraux,
Floor Van Ouytsel,
Romain Lambert,
Nicole Zhou,
Patricia Lavand'homme,
Andrea Penaloza,
Gisele Pickering Tags: ORIGINAL ARTICLE Source Type: research
Women authorship in pain research: A bibliometric analysis from 2002 to 2021
DiscussionOur data demonstrated increasing women authorship in pain journals in the past 20 years, largely driven by an increase in first authorships. There still remains a large gap between first and senior authorship, indicative of disparity in the role that women play in research. (Source: European Journal of Pain)
Source: European Journal of Pain - June 12, 2023 Category: Anesthesiology Authors: Haoyan Zhong,
Jashvant Poeran,
Crispiana Cozowicz,
Alex Illescas,
Jiabin Liu,
Stavros G. Memtsoudis Tags: SHORT COMMUNICATION Source Type: research
Chronic pain is no more prevalent in people living with HIV than in their uninfected counterparts in South Africa
ConclusionThe prevalence of chronic pain in South Africans living with HIV was approximately 20%, and having HIV was not associated with an increased risk of chronic pain.SignificanceUsing data from a large, national, population-based study in South Africa, I show for the first time that the prevalence of chronic pain in that population did not differ materially between the part of the population that was living with HIV compared with their uninfected counterparts (both approximately 20%). These findings run counter to the dogma that there is a greater risk of having pain in people living with HIV. (Source: European Journal of Pain)
Source: European Journal of Pain - June 8, 2023 Category: Anesthesiology Authors: Peter R. Kamerman Tags: SHORT COMMUNICATION Source Type: research
Cold ‐evoked potentials in clinical practice: A head‐to‐head contrast with laser‐evoked responses
ConclusionsCEPs appear as a useful technique for exploring pain/temperature systems. Advantages are low cost of equipment and innocuity. Disadvantages are low signal-to-noise ratio for LL stimulation, and sensitivity to fatigue/habituation. Joint recording of CEPs and LEPs can increase the sensitivity of neurophysiological techniques to thin fibre- spinothalamic lesions, in particular, when abnormalities of cold perception predominate.SignificanceRecording of cold-evoked potentials is a well-tolerated, inexpensive and easy-to-use procedure that can be helpful in the diagnosis of abnormalities in the thin fibre- spinothalam...
Source: European Journal of Pain - June 7, 2023 Category: Anesthesiology Authors: Caroline Perchet,
Koichi Hagiwara,
Charbel Salameh,
Luis Garcia ‐Larrea Tags: ORIGINAL ARTICLE Source Type: research
Pain ‐free default mode network connectivity contributes to tonic experimental pain intensity beyond the role of negative mood and other pain‐related factors
ConclusionsThis work suggests that pain-free mPFC-lAG connectivity (at lower alpha) may contribute to individual variations in pain-related vulnerability.SignificanceThese findings could potentially lead the way for investigations in which DMN connectivity is used in identifying individuals more likely to develop chronic pain. (Source: European Journal of Pain)
Source: European Journal of Pain - June 1, 2023 Category: Anesthesiology Authors: Najah Alhajri,
Shellie Ann Boudreau,
Andr é Mouraux,
Thomas Graven‐Nielsen Tags: ORIGINAL ARTICLE Source Type: research
Long ‐term opioid treatment and endocrine measures in chronic non‐cancer pain patients
ConclusionsOur study not only supports previous findings but even more interestingly disclosed new associations. We recommend future studies to investigate endocrine effects of opioids in larger, longitudinal studies. In the meanwhile, we recommend monitoring endocrine function in CNCP patients when prescribing L-TOT.SignificanceThis clinical study found associations between L-TOT, androgens, growth hormone and prolactin in patients with CNCP compared to controls. The results support previous studies as well as add new knowledge to the field, including an association between high opioid dose and low growth hormone levels. ...
Source: European Journal of Pain - May 27, 2023 Category: Anesthesiology Authors: Pernille D. K. Diasso,
Dalia Abou ‐Kassem,
Susanne D. Nielsen,
Katharina M. Main,
Per Sjøgren,
Geana P. Kurita Tags: ORIGINAL ARTICLE Source Type: research
Testing of a predictive risk index for persistent postsurgical pain on patients undergoing total knee arthroplasty: A prospective cohort study
ConclusionsAlthough the investigated risk index might predict clinically important differences in PPP between the risk groups at 3 months after TKA, it seems poorly applicable for predicting PPP at 12 months after TKA.SignificanceAlthough many risk factors for persistent postsurgical pain after total knee arthroplasty have been identified, predicting the risk of this pain has remained a challenge. Results of the current study suggest that accumulation of previously presented modifiable risk factors might be associated with increased postsurgical pain at 3 months, but not at 12 months after total knee arthroplasty...
Source: European Journal of Pain - May 27, 2023 Category: Anesthesiology Authors: Riku Palanne,
Mikko Rantasalo,
Anne Vakkuri,
Klaus T. Olkkola,
Tero Vahlberg,
Noora Skants Tags: ORIGINAL ARTICLE Source Type: research
