Assessing the impacts of smoking cessation and resumption on back pain risk in later life
ConclusionsOlder adults who avoided smoking for over 4 years had a lower risk of back pain. However, those who resumed smoking within 4 years had a higher risk of back pain.SignificanceOlder adults who avoided smoking for over 4 years had a lower risk of back pain. However, those who resumed smoking within 4 years had a higher risk of back pain. Our study data suggest the importance of maintaining smoking cessation to reduce the risk of back pain in the older population. (Source: European Journal of Pain)
Source: European Journal of Pain - May 26, 2023 Category: Anesthesiology Authors: Takaaki Ikeda,
Upul Cooray,
Masayasu Murakami,
Ken Osaka Tags: ORIGINAL ARTICLE Source Type: research
Comments on the importance of visualizing the distribution of pain ‐related data
(Source: European Journal of Pain)
Source: European Journal of Pain - May 25, 2023 Category: Anesthesiology Authors: J örn Lötsch,
Alfred Ultsch Tags: COMMENTARY Source Type: research
‘A whirlwind of everything’: The lived experience of adolescents with co‐occurring chronic pain and mental health symptoms
ConclusionCo-occurring pain and mental health symptoms may be experienced in similar ways to individually experienced pain or mental health symptoms, but together, the experience may be both more difficult to manage and more socially isolating.SignificanceAdolescents with co-occurring chronic pain and mental health symptoms describe the experience as if there was a storm inside of them disrupting their sense of physical, emotional and social wellbeing. This inner chaos interferes with their self-identity and relationships with others. Challenges articulating their experiences, and negative encounters associated with their ...
Source: European Journal of Pain - May 22, 2023 Category: Anesthesiology Authors: Jenny Corser,
Line Caes,
Sharon Bateman,
Melanie Noel,
Abbie Jordan Tags: ORIGINAL ARTICLE Source Type: research
NS5806 reduces carrageenan ‐evoked inflammation by suppressing extracellular signal‐regulated kinase activation in primary sensory neurons and immune cells
ConclusionsActing like an ERK pathway inhibitor, NS5806 reduces inflammation-evoked mechanical allodynia, thermal hyperalgesia, and edema by suppressing ERK activation in primary sensory neurons, mast cells, and macrophages.SignificancePrevious studies show that NS5806 only acts on neurons. This report unveils that NS5806 also acts on immune cells in the skin to exert its anti-inflammatory effects. Since NS5806 is lipid soluble for skin penetration, it suggests that NS5806 could also be developed into an anti-inflammatory drug for external use. (Source: European Journal of Pain)
Source: European Journal of Pain - May 13, 2023 Category: Anesthesiology Authors: Po ‐Yu Yang,
Meei‐Ling Tsaur Tags: ORIGINAL ARTICLE Source Type: research
Pain tolerance after stroke: The Troms ø study
ConclusionsStroke survivors, with and without chronic pain, had lower cold pressor pain tolerance, with possible clinical implications for pain in this group.SignificanceWe found lower pain tolerance in participants with previous stroke compared to stroke-free participants of a large, population-based study. The association was present both in those with and without chronic pain. The results may warrant increased awareness by health professionals towards pain experienced by stroke patients in response to injuries, diseases and procedures. (Source: European Journal of Pain)
Source: European Journal of Pain - May 12, 2023 Category: Anesthesiology Authors: Tonje Anita Melum,
Anders P. Årnes,
Hein Stigum,
Audun Stubhaug,
Ólöf Anna Steingrímsdóttir,
Ellisiv B. Mathiesen,
Christopher S. Nielsen Tags: ORIGINAL ARTICLE Source Type: research
Mental disorder prevalence in chronic pain patients using opioid versus non ‐opioid analgesics: A registry‐linkage study
ConclusionsMental health diagnoses are common in chronic pain patients receiving analgesics, particularly among young individuals and opioid users. The combination of opioid use and high psychiatric comorbidity suggests that prescribers should attend to mental health in addition to somatic pain.SignificanceThis large-scale study with nation-wide registry data supports previous findings of high psychiatric burden in chronic pain patients. Opioid users had significantly higher prevalence of mental health diagnoses, regardless of age and gender compared to users of non-opioid analgesics. Opioid users with chronic pain therefo...
Source: European Journal of Pain - May 4, 2023 Category: Anesthesiology Authors: L. C. Gjerde,
S. Skurtveit,
M. Handal,
R. Nesv åg,
T. Clausen,
T. G. Lid,
A. Hamina,
P. C. Borchgrevink,
I. Odsbu Tags: ORIGINAL ARTICLE Source Type: research
Glass half full: A diary and interview qualitative investigation of flourishing among adolescents living with chronic pain
ConclusionsWe conclude that adolescents can experience positive changes in functioning and flourish in some domains of life despite, or resulting from, chronic pain. Further research with an exclusive focus on flourishing is needed to build on this work and address this important gap in knowledge.SignificanceWe present evidence that adolescents can flourish when living with chronic pain. Such knowledge may inform the development of positive psychological treatment strategies that are focused on reinforcing adolescents ’ existing strengths, to expand on current treatment options for adolescents living with chronic pain. (...
Source: European Journal of Pain - May 3, 2023 Category: Anesthesiology Authors: Ryan D. Parsons,
Joanna L. McParland,
Sarah L. Halligan,
Liesbet Goubert,
Abbie Jordan Tags: ORIGINAL ARTICLE Source Type: research
Personalized treatment of neuropathic pain: Where are we now?
ConclusionWe discuss here the advantages and limitations of these approaches, which are not mutually exclusive.SignificanceRecent data indicate that various new treatment strategies based on predictive biological and/or clinical markers could be helpful to better personalized and therefore improve the management of neuropathic pain. (Source: European Journal of Pain)
Source: European Journal of Pain - April 29, 2023 Category: Anesthesiology Authors: Didier Bouhassira,
Nadine Attal Tags: REVIEW ARTICLE Source Type: research
Personalized medicine: Somatosensory phenotyping in musculoskeletal pain conditions
ConclusionsCurrent somatosensory measures will unlikely be validated as strong prognostic or predictive biomarkers. However, they still have the potential to support personalized medicine. Including somatosensory measures in biomarker signatures, that is, a set of measures that are collectively associated with outcomes, is potentially more useful than aiming to the identification of single biomarkers. Furthermore, somatosensory phenotyping may be introduced as part of patient's evaluation to contribute to better-informed and personalized treatment decisions. To this purpose, a change in the way research currently approache...
Source: European Journal of Pain - April 26, 2023 Category: Anesthesiology Authors: Michele Curatolo Tags: POSITION PAPER Source Type: research
Characterizing biased visuospatial perception in complex regional pain syndrome
ConclusionsPatients' cognitive strategies will be important to consider when studying inter-individual differences in the cognitive symptomatology and associated cognitive-based rehabilitation procedures in CRPS.SignificanceThe existence of biases in visuospatial perception in Complex Regional Pain Syndrome has been reported but not always systematically replicated. We show that these biases might depend on the type of general rehabilitation program that the patients follow. Patients ’ individual cognitive strategies will be important to consider when studying the cognitive symptomatology of CRPS. (Source: European Journal of Pain)
Source: European Journal of Pain - April 22, 2023 Category: Anesthesiology Authors: Lieve Filbrich,
Avgustina Kuzminova,
Victoria Molitor,
Charlotte Verfaille,
Dominique Mouraux,
Anne Berquin,
Olivier Barbier,
Xavier Libouton,
Val éry Legrain Tags: ORIGINAL ARTICLE Source Type: research
Issue Information
(Source: European Journal of Pain)
Source: European Journal of Pain - April 17, 2023 Category: Anesthesiology Tags: ISSUE INFORMATION Source Type: research
The role of the bone in complex regional pain syndrome 1 —A systematic review
ConclusionThe limited data reviewed revealed certain potential bone-related biomarkers in CRPS. Biomarkers hold the potential to identify patients who may benefit from treatments that influence bone turnover. Thus, this review identifies important areas for future research in CRPS1 patients. (Source: European Journal of Pain)
Source: European Journal of Pain - April 9, 2023 Category: Anesthesiology Authors: Gil Kollmann,
Maria M. Wertli,
Stefan Dudli,
Oliver Distler,
Florian Brunner Tags: REVIEW ARTICLE Source Type: research
Authors' reply to the comment ‘The importance of measurement content and study design’ by Veirman et al. (2023)
(Source: European Journal of Pain)
Source: European Journal of Pain - April 3, 2023 Category: Anesthesiology Authors: Mojtaba Habibi Asgarabad,
Pardis Salehi Yegaei,
Saber Azami‐Aghdash,
Mark A. Lumley Tags: LETTER TO THE EDITOR Source Type: research
The role of the bone in Complex Regional Pain Syndrome 1 – A systematic review
AbstractThe aim of this systematic review was to appraise and analyze the knowledge on bone-related biochemical and histological biomarkers in Complex Regional Pain Syndrome 1 (CRPS 1).A total of 7 studies were included in the analysis (biochemical analyses n=3, animal study n=1, histological examination n=3). Two studies were classified as having low risk of bias and five studies with a moderate risk of bias. Biochemical analysis indicated an increased bone turnover with increased bone resorption (elevated urinary levels of deoxypyridinoline) and bone formation (increased serum levels of calcitonin, osteoprotegrin and alk...
Source: European Journal of Pain - April 1, 2023 Category: Anesthesiology Authors: Gil Kollmann,
Maria M. Wertli,
Stefan Dudli,
Oliver Distler,
Florian Brunner Tags: REVIEW ARTICLE Source Type: research
Yoga and massage are associated with small experimental placebo effects in chronic orofacial pain
ConclusionsOur findings suggest that use of physically oriented CIHA was associated with experimental placebo effects possibly through an optimized capability to recognize distinct somatosensorial stimulations. Future research is needed to understand the mechanisms underlying placebo-induced pain modulation in CIHA users.SignificanceChronic pain participants who use physically oriented mind –body practices, such as yoga and massage, demonstrated attenuated experimentally induced placebo hypoalgesia in comparison with those who do not use them. This finding disentangled the relationship between use of complementary and in...
Source: European Journal of Pain - March 31, 2023 Category: Anesthesiology Authors: Margaret Yin,
Salim A. Muhammed,
Yang Wang,
Luana Colloca Tags: ORIGINAL ARTICLE Source Type: research
