A novel anoikis-related signature predicts prognosis risk and treatment responsiveness in diffuse large B-cell lymphoma
CONCLUSION: The ARG-based signature may provide a promising direction for prognosis prediction and treatment optimization for DLBCL patients.PMID:38709202 | DOI:10.1080/14737159.2024.2351465 (Source: Cancer Control)
Source: Cancer Control - May 6, 2024 Category: Cancer & Oncology Authors: Mingze Guan Hua Zhao Qi Zhang Li Li Xiaobo Wang Bo Tang Source Type: research
Disparities in Multiple Myeloma Mortality Rate Trends by Demographic Status in the USA
CONCLUSION: These findings suggest which populations are at increased risk for mortality due to multiple myeloma and where we should apply additional resources and research.PMID:38707728 | PMC:PMC11062173 | DOI:10.21873/cdp.10322 (Source: Cancer Control)
Source: Cancer Control - May 6, 2024 Category: Cancer & Oncology Authors: Sishir Doddi M Hammad Rashid Source Type: research
Psychological Group Interventions for Reducing Distress Symptoms in Healthcare Workers: A Systematic Review
Clin Psychol Psychother. 2024 May-Jun;31(3):e2980. doi: 10.1002/cpp.2980.ABSTRACTHealthcare workers exposed to emergencies and chronic stressors are at high risk of developing mental health problems. This review synthesized existing studies of group psychological therapy to reduce distress symptoms in healthcare workers (i.e., as complex and heterogeneous emotional states, characterized by the presence of symptoms associated with post-traumatic stress disorder, burnout, anxiety, depression and moral injury). Searches were conducted using PRISMA guidelines and databases such as PubMed, PsycINFO, Medline and Web of Science, ...
Source: Clinical Psychology and Psychotherapy - May 6, 2024 Category: Psychiatry Authors: Sandra Sanz Carmen Valiente Regina Espinosa Almudena Trucharte Source Type: research
A systematic review/meta-analysis of prevalence and incidence rates illustrates systemic underrepresentation of individuals racialized as Asian and/or Asian-American in ADRD research
Alzheimers Dement. 2024 May 6. doi: 10.1002/alz.13820. Online ahead of print.ABSTRACTWe investigate Alzheimer's disease and related dementia (ADRD) prevalence, incidence rate, and risk factors in individuals racialized as Asian and/or Asian-American and assess sample representation. Prevalence, incidence rate, risk factors, and heterogeneity of samples were assessed. Random-effects meta-analysis was conducted, generating pooled estimates. Of 920 records across 14 databases, 45 studies were included. Individuals racialized as Asian and/or Asian-American were mainly from Eastern and Southern Asia, had higher education, and c...
Source: The Journal of Alzheimers Association - May 6, 2024 Category: Psychiatry Authors: Yiqi Zhu Soobin Park Ramana Kolady Wenqing Zha Ying Ma Amanda Dias Katherine McGuire Angela Hardi Sunny Lin Zahinoor Ismail Paris B Adkins-Jackson Jean-Francois Trani Ganesh M Babulal Source Type: research
Impact of body mass index at diagnosis on outcomes of pediatric acute leukemia: A systematic review and meta-analysis
ConclusionsBoth underweight and obese status at the time of diagnosis were associated with poor survival outcomes in pediatric patients with leukemia. (Source: PLoS One)
Source: PLoS One - May 6, 2024 Category: Biomedical Science Authors: Ling Dong Source Type: research
Risk of transmission of HIV to infants during breast/chest feeding when mothers/birthing parents living with HIV are on antiretroviral therapy: a protocol for a rapid review
The objective of this rapid review is to explore and assess the available evidence on the effect of varying viral load levels on the risk of HIV transmission to infants during breast/chest feeding when the birthing or gestational parent living with HIV is on ART. Study characteristics will be summarised and reported to support the narrative summary of the findings. The focus will be on the absolute risk of HIV transmission from birthing parent to infant during chest/breast feeding. The findings will also be stratified by month, including the risk of HIV transmission for 6 months and greater than 6 months postpartum. We wil...
Source: BMJ Open - May 6, 2024 Category: General Medicine Authors: Djiadeu, P., Begum, H., Archibald, C., Ekmekjian, T., Busa, G., Dansoh, J., Van Nguyen, P., Merckx, J., Fleurant, A. Tags: Open access HIV/AIDS Source Type: research
Genes, Vol. 15, Pages 589: Genome-Wide Identification and Characterization of the PHT1 Gene Family and Its Response to Mycorrhizal Symbiosis in Salvia miltiorrhiza under Phosphate Stress
In this study, to gain insight into the functional divergence of PHT1 genes, nine SmPHT1 genes were identified in the S. miltiorrhiza genome database via bioinformatics tools. Phylogenetic analysis revealed that the PHT1 proteins of S. miltiorrhiza, Arabidopsis thaliana, and Oryza sativa could be divided into three groups. PHT1 in the same clade has a similar gene structure and motif, suggesting that the features of each clade are relatively conserved. Further tissue expression analysis revealed that SmPHT1 was expressed mainly in the roots and stems. In addition, phenotypic changes, P content, and PHT1 gene expression wer...
Source: Genes - May 6, 2024 Category: Genetics & Stem Cells Authors: Xue Chen Yanhong Bai Yanan Lin Hongyan Liu Fengxia Han Hui Chang Menglin Li Qian Liu Tags: Article Source Type: research
Sensors, Vol. 24, Pages 2948: Enhancing Fetal Electrocardiogram Signal Extraction Accuracy through a CycleGAN Utilizing Combined CNN & ndash;BiLSTM Architecture
Sensors, Vol. 24, Pages 2948: Enhancing Fetal Electrocardiogram Signal Extraction Accuracy through a CycleGAN Utilizing Combined CNN–BiLSTM Architecture
Sensors doi: 10.3390/s24092948
Authors:
Yuyao Yang
Lin Chen
Shuicai Wu
The fetal electrocardiogram (FECG) records changes in the graph of fetal cardiac action potential during conduction, reflecting the developmental status of the fetus in utero and its physiological cardiac activity. Morphological alterations in the FECG can indicate intrauterine hypoxia, fetal distress, and neonatal asphyxia early on, enhancing maternal and fetal safety through prom...
Source: Sensors - May 6, 2024 Category: Biotechnology Authors: Yuyao Yang Lin Chen Shuicai Wu Tags: Article Source Type: research
Association between non-alcoholic fatty liver disease and risk of sarcopenia: a systematic review and meta-analysis
Conclusions and implications
The current study indicated a significant positive correlation between NAFLD and sarcopenia, which may be affected by regional factors. This study provides the correlation basis for the relationship between NAFLD and sarcopenia and helps to find the quality strategy of sarcopenia targeting NAFLD. (Source: BMJ Open)
Source: BMJ Open - May 6, 2024 Category: General Medicine Authors: Deng, C., Ou, Q., Ou, X., Pan, D. Tags: Open access, Public health Source Type: research
The EFEMEREYE Study: prenatal medication exposure and ocular anomaly occurrence in EFEMERIS health database
To describe ocular anomalies (OAs) in children and fetuses in a French general population, to estimate their prevalence, and to investigate a possible association between prenatal medication exposure and the occurrence of OA in utero or in early childhood. (Source: Journal of AAPOS)
Source: Journal of AAPOS - May 6, 2024 Category: Opthalmology Authors: Charlotte Dubucs, Van N ’Go, Anthony Caillet, Erika-Alejandra Cifuentes, Anna-Belle Beau, Félix Frémont, Caroline Hurault-Delarue, Monique Courtade-Saïdi, Christine Damase-Michel Tags: Major Article Source Type: research
Endovascular therapy versus bypass for chronic limb-threatening ischemia in a real-world practice
The recent BEST-CLI study showed that bypass was superior to endovascular therapy (ET) in patients with chronic limb threatening ischemia (CLTI) deemed suitable for either approach who had an available single segment great saphenous vein (GSV). However, the superiority of bypass among those lacking GSV was not established. We aimed to examine comparative treatment outcomes from a real-world CLTI population using the Vascular Quality Initiative (VQI)-Medicare-Linked database. (Source: Journal of Vascular Surgery)
Source: Journal of Vascular Surgery - May 6, 2024 Category: Surgery Authors: Sina Zarrintan, Shima Rahgozar, Elsie G. Ross, Alik Farber, Matthew T. Menard, Michael S. Conte, Mahmoud B. Malas Source Type: research
Empowering children for better health with child-to-child approach: a systematic literature review
Palka Mittal, Sheetal Kalra, Abhishek Dadhich, Puneeta Ajmera Health Education, Vol. ahead-of-print, No. ahead-of-print, pp.- Child-to-Child (C-to-C) approach is an evidence-based approach that ensures the child’s participation in bringing about positive changes in healthcare. By systematically investigating the literature, the study aimed to evaluate the effectiveness of the approach and recognize associated themes, methodologies and outcomes.An extensive search on PubMed, ProQuest, Cochrane and Dimensions AI databases was performed for original research articles on C-to-C intervention, with no time and geographical re...
Source: Health Education - May 5, 2024 Category: International Medicine & Public Health Authors: Palka Mittal Sheetal Kalra Abhishek Dadhich Puneeta Ajmera Source Type: research
A meta-analysis of coping strategies and psychological distress in rheumatoid arthritis
CONCLUSIONS: Findings from this first meta-analysis of coping and distress in RA indicate that maladaptive but not adaptive coping is associated with greater distress. Further research is needed to grow the evidence base to verify the current findings especially with respect to adaptive coping.PMID:38705871 | DOI:10.1111/bjhp.12726 (Source: British Journal of Health Psychology)
Source: British Journal of Health Psychology - May 5, 2024 Category: Psychiatry & Psychology Authors: Rebecca Hinch Fuschia M Sirois Source Type: research
Factors Influencing Palliative and End-of-Life Care for Adults with Intellectual Disabilities: A Scoping Review of Health and Care Workers' Experiences
J Soc Work End Life Palliat Care. 2024 May 5:1-19. doi: 10.1080/15524256.2024.2346113. Online ahead of print.ABSTRACTIn developed countries, there has been an increase in the longevity of adults with intellectual disabilities. In the later stages of their lives, people with intellectual disability have specific needs in terms of palliative and end-of-life care that need to be better understood in order to offer appropriate care. This scoping review aimed to identify the main factors influencing the provision of palliative and end-of-life care from the perspective of health and care workers involved with adults with an inte...
Source: Journal of Social Work in End-of-Life and Palliative Care - May 5, 2024 Category: Palliative Care Authors: Romane Couvrette É Milot G Fortin Source Type: research
Evaluating the efficacy and safety of nivolumab and ipilimumab combination therapy compared to nivolumab monotherapy in advanced cancers (excluding melanoma): a systemic review and meta-analysis
CONCLUSIONS: Combining nivolumab and ipilimumab did not significantly improve overall survival compared to nivolumab alone in advanced cancers (except melanoma). However, it did show slightly better PFS at the cost of increased toxicity, particularly grades 3-4 adverse events. Specific AEs occurred more frequently in the combination group. Further trials are needed to fully assess this combination in treating advanced cancers.PMID:38705953 | DOI:10.1186/s43046-024-00218-2 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - May 5, 2024 Category: Cancer & Oncology Authors: Hussain Sohail Rangwala Hareer Fatima Mirha Ali Sailesh Sunder Sonia Devi Burhanuddin Sohail Rangwala Syed Raza Abbas Source Type: research
