Response to "Upping the dose of dementia risk reduction"
Alzheimers Dement. 2022 May 16. doi: 10.1002/alz.12693. Online ahead of print.NO ABSTRACTPMID:35575626 | DOI:10.1002/alz.12693 (Source: The Journal of Alzheimers Association)
Source: The Journal of Alzheimers Association - May 16, 2022 Category: Psychiatry Authors: Sylvie Belleville Simon Cloutier Samira Mellah Bruno Vellas Sandrine Andrieu Nicola Coley Tiia Ngandu Source Type: research

Upping the dose of dementia risk reduction
Alzheimers Dement. 2022 May 8. doi: 10.1002/alz.12692. Online ahead of print.NO ABSTRACTPMID:35527368 | DOI:10.1002/alz.12692 (Source: The Journal of Alzheimers Association)
Source: The Journal of Alzheimers Association - May 9, 2022 Category: Psychiatry Authors: Timothy Daly Source Type: research

Higher Dietary Inflammatory Index scores are associated with brain MRI markers of brain aging: Results from the Framingham Heart Study Offspring cohort
DISCUSSION: Our findings showed associations between higher DII scores and global brain MRI measures. As we are one of the first groups to report on the associations between higher DII scores and brain volume, replication is needed to confirm our findings.PMID:35522830 | DOI:10.1002/alz.12685 (Source: The Journal of Alzheimers Association)
Source: The Journal of Alzheimers Association - May 6, 2022 Category: Psychiatry Authors: Deborah Melo Van Lent Hannah Gokingco Meghan I Short Changzheng Yuan Paul F Jacques Jos é R Romero Charles S DeCarli Alexa S Beiser Sudha Seshadri Jayandra J Himali Mini E Jacob Source Type: research

The role of mitochondrial dysfunction in Alzheimer's disease pathogenesis
Alzheimers Dement. 2022 May 6. doi: 10.1002/alz.12683. Online ahead of print.ABSTRACTTo promote new thinking of the pathogenesis of Alzheimer's disease (AD), we examine the central role of mitochondrial dysfunction in AD. Pathologically, AD is characterized by progressive neuronal loss and biochemical abnormalities including mitochondrial dysfunction. Conventional thinking has dictated that AD is driven by amyloid beta pathology, per the Amyloid Cascade Hypothesis. However, the underlying mechanism of how amyloid beta leads to cognitive decline remains unclear. A model correctly identifying the pathogenesis of AD is critic...
Source: The Journal of Alzheimers Association - May 6, 2022 Category: Psychiatry Authors: Theophania Ashleigh Russell H Swerdlow M Flint Beal Source Type: research

Higher Dietary Inflammatory Index scores are associated with brain MRI markers of brain aging: Results from the Framingham Heart Study Offspring cohort
DISCUSSION: Our findings showed associations between higher DII scores and global brain MRI measures. As we are one of the first groups to report on the associations between higher DII scores and brain volume, replication is needed to confirm our findings.PMID:35522830 | DOI:10.1002/alz.12685 (Source: The Journal of Alzheimers Association)
Source: The Journal of Alzheimers Association - May 6, 2022 Category: Psychiatry Authors: Deborah Melo Van Lent Hannah Gokingco Meghan I Short Changzheng Yuan Paul F Jacques Jos é R Romero Charles S DeCarli Alexa S Beiser Sudha Seshadri Jayandra J Himali Mini E Jacob Source Type: research

The role of mitochondrial dysfunction in Alzheimer's disease pathogenesis
Alzheimers Dement. 2022 May 6. doi: 10.1002/alz.12683. Online ahead of print.ABSTRACTTo promote new thinking of the pathogenesis of Alzheimer's disease (AD), we examine the central role of mitochondrial dysfunction in AD. Pathologically, AD is characterized by progressive neuronal loss and biochemical abnormalities including mitochondrial dysfunction. Conventional thinking has dictated that AD is driven by amyloid beta pathology, per the Amyloid Cascade Hypothesis. However, the underlying mechanism of how amyloid beta leads to cognitive decline remains unclear. A model correctly identifying the pathogenesis of AD is critic...
Source: The Journal of Alzheimers Association - May 6, 2022 Category: Psychiatry Authors: Theophania Ashleigh Russell H Swerdlow M Flint Beal Source Type: research