Psychedelics for psychological and existential distress in palliative and cancer care.
Authors: Rosenbaum D, Boyle AB, Rosenblum AM, Ziai S, Chasen MR, Med MP PMID: 31548800 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Evolution of adolescent and young adult oncology in Canada.
Authors: DePauw S, Rae C, Schacter B, Rogers P, Barr RD PMID: 31548801 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Utility of a chemotherapy toxicity prediction tool for older patients in a community setting.
Conclusions: This study demonstrates that use of a brief geriatric assessment tool is possible in a broad community oncology practice. The tool modified the oncologist's supportive care plan for a significant number of older patients undertaking cytotoxic chemotherapy. PMID: 31548802 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

An evaluation of the safety of continuing trastuzumab despite overt left ventricular dysfunction.
Conclusions: Many patients with mildly reduced lvef and minimal heart failure symptoms might be able to continue trastuzumab without further decline in lvef, adverse cardiac events, or death when treated under the supervision of a cardiologist with close follow-up. PMID: 31548803 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Resource use in the last three months of life by lung cancer patients in southern Ontario.
Conclusions: Use of acute-care services and rates of death in an acute-care facility are both high for lung cancer patients approaching end of life. In our study, interprofessional and patient-provider communication, earlier connection to homecare services, and improved access to community care were highlighted as having the potential to lower the need for acute-care resources. PMID: 31548804 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Emerging therapies for the treatment of relapsed or refractory diffuse large B cell lymphoma.
Authors: Skrabek P, Assouline S, Christofides A, MacDonald D, Prica A, Sangha R, Matthews BA, Sehn LH Abstract Diffuse large B cell lymphoma (dlbcl) is an aggressive non-Hodgkin lymphoma, accounting for approximately 30% of lymphoma cases in Canada. Although most patients will achieve a cure, up to 40% will experience refractory disease after initial treatment, or relapse after a period of remission. In eligible patients, salvage therapy followed by high-dose therapy and autologous stem-cell transplantation (asct) is the standard of care. However, many patients are transplant-ineligible, and more than half of those...
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Inter- and intraprovincial inequities in public coverage of cancer drug programs across Canada: a plea for the establishment of a pan-Canadian pharmacare program.
Authors: Sorin M, Franco EL, Quesnel-Vallée A PMID: 31548806 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Impact of the Knowledge Translation Research Network's grants program in cancer knowledge translation.
Authors: O'Brien MA, Grunfeld E PMID: 31548807 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Lessons learned from a cancer knowledge translation grants program: results of an evaluation.
Conclusions: The grants program met many of its aims by providing cancer researchers with an opportunity to gain capacity in cancer kt and by making incremental advances in kt science. Suggestions to improve the program included closer partnerships between the funder and the cancer-system organization. PMID: 31548808 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

The role of metronomic chemotherapy in the era of cancer immunotherapy: an oncologist's perspective.
Authors: Tsao SY PMID: 31548809 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Cannabis use in cancer: a survey of the current state at BC Cancer before recreational legalization in Canada.
Conclusions: More than half the respondents had tried cannabis at some time, and almost one quarter of respondents were currently taking cannabis to help manage their symptoms or treat their cancer, or both. Many more patients would consider use with appropriate guidance from a health care professional. More research is needed to inform physicians and patients about safe uses and doses and about the potential adverse effects of cannabis use. PMID: 31548810 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Feasibility of a modified Atkins diet in glioma patients during radiation and its effect on radiation sensitization.
Conclusions: A modified Atkins diet is feasible and safe for glioma patients during radiation and chemotherapy treatment. The mad and resulting ketosis could play a role as a radiation sensitizer. PMID: 31548811 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Exploring reasons for overuse of contralateral prophylactic mastectomy in Canada.
Conclusions: Multiple factors discouraging and encouraging the use of cpm in unilateral bca were identified. Those factors identify potential individual, team, organization, and system targets for behaviour change interventions to reduce cpm. PMID: 31548812 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

18 F-Fluorodeoxyglucose positron-emission tomography for the investigation of malignancy in patients with suspected paraneoplastic neurologic syndromes and negative or indeterminate conventional imaging: a retrospective analysis of the Ontario PET Access Program, with systematic review and meta-analysis.
Conclusions: When investigating for underlying malignancy in patients with suspected pns and negative conventional imaging, pet has high sensitivity and specificity. PMID: 31548813 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

FOLFIRINOX in patients with peritoneal carcinomatosis from pancreatic adenocarcinoma: a retrospective study.
Conclusions: Compared with other metastatic sites, synchronous pcm seems to be a poor prognostic factor. It could be more frequently associated with a poor ecog ps and a nlr greater than 5 in this group of patients. In patients with mpdac and pcm, either synchronous or metachronous, folfirinox remains an efficient regimen. PMID: 31548814 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Incidence and mortality trends and geographic patterns of follicular lymphoma in Canada.
Conclusions: Our study provides a comprehensive overview of the fl burden and its geographic distribution in Canada. Regional clustering of this disease in concentrated industrial zones strongly suggests that multiple environmental factors might play a crucial role in the development of this lymphoma. PMID: 31548815 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

The patient experience of ambulatory cancer treatment: a descriptive study.
Conclusions: The results identify facilitators and barriers to the patient experience in the ambulatory cancer treatment setting from the patient perspective and identify opportunities to improve the patient experience. PMID: 31548816 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Who cares? The impact on caregivers of suspected mining-related lung cancer.
Conclusions: Caregivers expressed a need for more education about the compensation process and for greater support. Worker representatives required persistence, additional workplace monitoring and controls, additional research, and a focus on compensation compared with cost control. They also emphasized the need for more family support. PMID: 31548817 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Patient-reported outcomes in Alberta: rationale, scope, and design of a database initiative.
Discussion: Because this effort represents our first to integrate routinely collected pros with other administrative health data, a unique and robust data repository will be created. The ability to integrate various types of data will provide a comprehensive mechanism to evaluate a variety of outcomes. Because cancer care in Alberta is governed by a single health care system, the data linkages will include population health and psychosocial cancer data. We anticipate that research related to this initiative will ultimately help to inform more patient-centred care. PMID: 31548818 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Employment outcomes for recent Canadian radiation oncology graduates.
Conclusions: Employment challenges for newly certified Canadian-trained radiation oncologists continue. However, compared with the situation 2 years ago, trends in the Canadian ro job market suggest a modest improvement, with more staff employment in Canada and lower emigration rates for jobs abroad. PMID: 31548819 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Outcomes after intensity-modulated compared with 3-dimensional conformal radiotherapy with chemotherapy for squamous cell carcinoma of the anal canal.
Conclusions: The recommended use of imrt with concurrent chemotherapy as an improvement over 3D-crt for management of anal canal carcinoma achieves a high probability of local control and colostomy-free survival without excessive risk for acute or late treatment-related toxicities. PMID: 31548820 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Mastectomy versus breast-conservation therapy: an examination of how individual, clinicopathologic, and physician factors influence decision-making.
Conclusions: Our study demonstrates that treatment choices for Saskatchewan women with esbca are influenced primarily by disease stage and individual belief factors. Those findings suggest that women are making their treatment choices predominantly based on individual values and preferences. The use of rates of mastectomy and bct as indicators of quality of care might be misleading. Instead, a shift in attention toward patient-centred care might be more appropriate. PMID: 31548821 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Active treatment in low-risk prostate cancer: a population-based study.
Conclusions: This contemporary population-based study demonstrates that approximately one third of patients with lr-pca undergo at. Patients of younger age, with less comorbidity, a higher tumour stage, higher psa, earlier year of diagnosis, and radiation oncologist consultation were more likely to undergo at. Further investigation is needed to identify strategies that could minimize overtreatment. PMID: 31548822 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Primary excision margins, sentinel lymph node biopsy, and completion lymph node dissection in cutaneous melanoma: a clinical practice guideline.
Conclusions: Recommendations for primary excision margins, sentinel lymph node biopsy, and completion lymph node dissection in patients with cutaneous melanoma have been updated based on the current literature. PMID: 31548823 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Crizotinib inhibition of ROS1-positive tumours in advanced non-small-cell lung cancer: a Canadian perspective.
Authors: Bebb DG, Agulnik J, Albadine R, Banerji S, Bigras G, Butts C, Couture C, Cutz JC, Desmeules P, Ionescu DN, Leighl NB, Melosky B, Morzycki W, Rashid-Kolvear F, Lab C, Sekhon HS, Smith AC, Stockley TL, Torlakovic E, Xu Z, Tsao MS Abstract The ros1 kinase is an oncogenic driver in non-small-cell lung cancer (nsclc). Fusion events involving the ROS1 gene are found in 1%-2% of nsclc patients and lead to deregulation of a tyrosine kinase-mediated multi-use intracellular signalling pathway, which then promotes the growth, proliferation, and progression of tumour cells. ROS1 fusion is a distinct molecular subtype ...
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

A survey of health care professionals and oncology patients at the McGill University Health Centre reveals enthusiasm for establishing a postmortem rapid tissue donation program.
Conclusions: At the muhc, hcps and patients are generally enthusiastic about adopting a rtd program for patients with metastatic cancer. Education of hcps and patients will be an important determinant of the program's success. PMID: 31548825 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Pembrolizumab-induced obstructive bronchiolitis in a patient with stage IV non-small-cell lung cancer.
The objective of this case report was to review and point out a new pattern of immune checkpoint inhibitor-associated pneumonitis. Case Description: A 69-year-old woman with stage iv non-small-cell lung cancer receiving pembrolizumab presented for increased dyspnea. Pembrolizumab-related obstructive bronchiolitis was diagnosed based on a new severe obstructive disorder, without bronchodilator reversibility, and mosaic attenuation on angiography, without other identifiable causes. Summary: To our knowledge, this is the first description of a case of pembrolizumab-induced obstructive bronchiolitis. Various patterns o...
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Primary Ewing sarcoma of the larynx with distant metastasis: a case report and review of the literature.
Authors: Maroun CA, Khalifeh I, Tfayli A, Moukarbel RV Abstract Extraosseous Ewing sarcoma is a rare, poorly differentiated round-cell tumour that is part of the Ewing sarcoma family of tumours. Here, we present an extremely rare case of primary extraosseous Ewing sarcoma arising in the larynx, with distant metastases. A 53-year-old man with a history of Hodgkin lymphoma treated 4 years earlier with 8 cycles of chemotherapy presented to our medical centre with a 2-week history of hoarseness. On physical examination, he was found to have a right supraglottic mass together with a fixed right vocal cord. Computed tomo...
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Canadian Lung Cancer Conference 2019.
Authors: Pender A, Dunne EM, Wong SK, Ho C, Melosky B Abstract The 19th Canadian Lung Cancer Conference took place 7-8 February 2019 in Vancouver, British Columbia. This annual interdisciplinary education event attracted participants from throughout Canada to review the latest advances in lung cancer care and to learn from world-renowned experts in the field. The highlights of this year's conference were perspectives about biomarkers for immunotherapy, approaches to oligoprogressive disease, and caregiver burnout. PMID: 31548828 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Updates from the 2019 American Society of Clinical Oncology and European Hematology Association annual meetings: a Canadian perspective on high-risk cytogenetics in multiple myeloma.
Authors: LeBlanc R, Song K, White D, Christofides A, Doucette S Abstract The 2019 annual meetings of the American Society of Clinical Oncology and the European Hematology Association took place, respectively, in Chicago, Illinois, 31 May-4 June, and in Amsterdam, Netherlands, 13-16 June. At the meetings, results from key studies on the treatment of patients with relapsed or refractory multiple myeloma with high-risk cytogenetics were presented. Our meeting report describes those studies and includes interviews with investigators and commentaries by Canadian hematologists about the potential impact on Canadian pract...
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Reconsidering the turnaround times for BRAF V600 mutation analysis in non-small-cell lung cancer: a molecular diagnosis in one day is achievable for rapid treatment choices.
Authors: Uguen A PMID: 31548830 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - September 26, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Fulfilling the potential of real-world evidence for lung cancer in Canada.
Authors: Cheema PK, Kuruvilla S PMID: 31285656 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - July 11, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Strong reasons make strong actions: medical cannabis and cancer-a call for collective action.
Authors: Kerba M PMID: 31285657 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - July 11, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Countercurrents: Is now the right time to pull the plug on mammography?
Authors: Narod SA PMID: 31285658 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - July 11, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Whither palliative care?
Authors: Watt CL, Downar J PMID: 31285659 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - July 11, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

When the oncologist becomes the patient.
Authors: Aitini E PMID: 31285660 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - July 11, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Assessing the impact of mailing self-sampling kits for human papillomavirus testing to unscreened non-responder women in Manitoba.
Conclusions: The study demonstrated that hpv self-sampling kits can enhance screening participation in unscreened non-responder women in the setting of an organized screening program. Next steps should include additional research to determine the best implementation strategy for hpv self-sampling in Manitoba. PMID: 31285661 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - July 11, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Research priorities for the pan-Canadian Oncology Symptom Triage and Remote Support practice guides: a modified nominal group consensus.
Conclusions: Across categories, the top 3 priorities were effect on health services use, competency development, and a mobile costars solution. Future research will address identified priorities, reflecting the needs and perspectives of diverse stakeholders. Stakeholder collaboration will continue to guide our approach to operationalizing this priority research agenda. PMID: 31285662 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - July 11, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

A family with Sertoli-Leydig cell tumour, multinodular goiter, and DICER1 mutation.
We present a case in which a patient in her late 30s was diagnosed with a Sertoli-Leydig cell tumour in the background of a strong family history of multinodular goiter and Sertoli-Leydig cell tumour with a germline mutation in DICER1. Case Presentation: A 38-year-old woman with history of multinodular goiter was found to have stage iiic ovarian Sertoli-Leydig cell cancer after presenting with abdominal pain. She underwent multiple surgeries and chemotherapy. The patient developed rapid disease progression and died 7 months after diagnosis. Seven years earlier, a daughter had experienced the same disease and was found ...
Source: Current Oncology - July 11, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Crocodiles and alligators: physicians' answer to cancer?
Authors: Khan NA, Soopramanien M, Siddiqui R PMID: 31285664 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - July 11, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

A general practitioner's guide to hematopoietic stem-cell transplantation.
Authors: Bazinet A, Popradi G Abstract Hematopoietic stem-cell transplantation (hsct) is a medical procedure that consists of infusing stem cells after a short course of chemotherapy or radiotherapy, or both. It can be used in the treatment of various cancers, as well as some benign conditions. In the present review, we discuss the various types of hsct and their main indications. The principles of the transplant procedure itself and the basics of recipient selection are reviewed. Special attention is given to both the immediate and the long-term complications of hsct and their management strategies. Hematopoietic ...
Source: Current Oncology - July 11, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

An integrated knowledge translation approach to develop a shared decision-making strategy for use by Inuit in cancer care: a qualitative study.
Conclusions: An integrated kt approach of structured research processes with partners developed a sdm strategy for use by Inuit in cancer care. Further work is needed to test the sdm strategy. PMID: 31285666 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - July 11, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Testing e-mail content to encourage physicians to access an audit and feedback tool: a factorial randomized experiment.
Conclusions: For audit and feedback to work, recipients must engage with the data; for e-mail messages to prompt activity, recipients must open and review the message content. This large factorial experiment demonstrated that small changes in the content of such e-mail messages might influence clinical behaviour. Future research should focus on strategies to make cancer screening more user-centred. PMID: 31285667 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - July 11, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Accompanying a peaceful passing.
Authors: Schiappacasse GV, Schiappacasse ED PMID: 31285668 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - July 11, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Prognostic factors in Asian and white American patients with cervical cancer, considering competing risks.
Conclusions: Survival status differs for white and Asian American patients with cervical cancer. Our results could guide the treatment of, and facilitate prognostic judgments about, white and Asian American patients with cervical cancer. PMID: 31285669 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - July 11, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Measuring colposcopy quality in Canada: development of population-based indicators.
Authors: Decker K, Baines N, Muzyka C, Lee M, Mayrand MH, Yang H, Fung S, Mercer D, McFaul S, Kupets R, Savoie R, Lotocki R, Bentley J Abstract Background: Colposcopy is a key part of cervical cancer control. As cervical cancer screening and prevention strategies evolve, monitoring colposcopy performance will become even more critical. In the present paper, we describe population-based colposcopy quality indicators that are recommended for ongoing measurement by cervical cancer screening programs in Canada. Methods: The Pan-Canadian Cervical Cancer Screening Network established a multidisciplinary expert workin...
Source: Current Oncology - July 11, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Brain cancer survival in Canada 1996-2008: effects of sociodemographic characteristics.
Conclusions: Our analysis did not yield evidence of strong effects of rural compared with urban residence or ses strata on survival in brain cancer. However, some variation in survival for patients with specific histologies warrants further research into the mechanisms by which rural or urban residence and income stratum influences survival. PMID: 31285671 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - July 11, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Effectiveness of first-line treatments in metastatic squamous non-small-cell lung cancer.
Authors: Levy BP, Signorovitch JE, Yang H, Patterson-Lomba O, Xiang CQ, Parisi M Abstract Background: Commonly used first-line (1L) chemotherapies for patients with advanced squamous-cell lung cancer (scc) include gemcitabine-platinum (gp), nab-paclitaxel-carboplatin (nabpc), and sb-paclitaxel-carboplatin (sbpc) regimens. However, no head-to-head trials have compared those treatments. In the present study, we compared the efficacy of 1L gp, nabpc, and sbpc in patients with scc and in patients with scc who subsequently received second-line (2L) immunotherapy. Methods: Medical records of patients who initiated th...
Source: Current Oncology - July 11, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Screening for new primary cancers in patients with metastatic breast cancer: a provincial analysis of the Choosing Wisely Canada recommendations.
Conclusions: A significant proportion of patients with metastatic breast cancer in Newfoundland and Labrador are still undergoing screening for new primary malignancies, which is discordant with oncology guidelines from Choosing Wisely Canada. Increased education strategies are needed if the Choosing Wisely Canada recommendations are to be implemented into routine clinical practice. PMID: 31285673 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - July 11, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Effect of obesity, dyslipidemia, and diabetes on trastuzumab-related cardiotoxicity in breast cancer.
Conclusions: The combination of 2 or 3 comorbidities significantly increases the incidence of symptomatic cancer treatment-related cardiotoxicity. Patients with bca experiencing cancer treatment-related cardiotoxicity who have a history of diabetes, dyslipidemia, and obesity might require more proactive strategies for prevention, detection, and treatment of cardiotoxicity while receiving trastuzumab-based treatment. PMID: 31285674 [PubMed - in process] (Source: Current Oncology)
Source: Current Oncology - July 11, 2019 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research