[Corrigendum] miR ‑27a promotes proliferation, migration, and invasion of colorectal cancer by targeting FAM172A and acts as a diagnostic and prognostic biomarker
Oncol Rep. 2024 Jun;51(6):83. doi: 10.3892/or.2024.8742. Epub 2024 Apr 26.ABSTRACTFollowing the publication of this article, an interested reader drew to the authors' attention that the western blots in Fig. 4B on p. 3560 and Fig. 6B on p. 3562 shared remarkably similar data (including both the GAPDH and the FAM172A blots in Fig. 4B), such that these data were likely to have been derived from the same original source. Upon asking the authors to provide an explanation, the authors realized that these errors inadvertently arose during the process of assembling these figures. Due to a mislabelling of the files, representative...
Source: Oncology Reports - April 26, 2024 Category: Cancer & Oncology Authors: Wenjun Liu Kai Qian Xing Wei Haijun Deng Bei Zhao Qing Chen Jinqian Zhang Hao Liu Source Type: research
Involvement of lncRNAs in the regulation of aerobic glycolysis in hepatocellular carcinoma: Main functions, regulatory mechanisms and potential therapeutic implications (Review)
Oncol Rep. 2024 Jun;51(6):84. doi: 10.3892/or.2024.8743. Epub 2024 Apr 26.ABSTRACTEven under aerobic conditions, tumor cells can reprogram their metabolism to preferentially metabolize glucose into lactic acid. This abnormal metabolic pattern, known as the 'Warburg' effect or aerobic glycolysis, promotes cancer progression. Long non‑coding RNAs (lncRNAs) are RNAs that are >200 nucleotides in length and do not have protein‑coding capabilities. However, these RNAs play a key role in tumor development. There is increasing evidence to indicate that lncRNAs regulate glucose metabolism in tumor cells by affecting metaboli...
Source: Oncology Reports - April 26, 2024 Category: Cancer & Oncology Authors: Qiongqing Huang Zhengui Liang Qiqi Huang Xueyu Li Jingjing Xia Lining Huang Lin Bing Huang Chao Ou Source Type: research
[Retracted] Fangchinoline suppresses growth and metastasis of melanoma cells by inhibiting the phosphorylation of FAK
Oncol Rep. 2024 Jun;51(6):81. doi: 10.3892/or.2024.8740. Epub 2024 Apr 26.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the Transwell migration and invasion assay data shown in Fig. 3C and D on p. 67 were strikingly similar to data appearing in different form in another pair of articles written by different authors at different research institutes, one of which (subsequently retracted) had already been published elsewhere prior to the submission of this paper to Oncology Reports, with the other having been submitted for publication at around th...
Source: Oncology Reports - April 26, 2024 Category: Cancer & Oncology Authors: Jie Shi Bingyu Guo Qiang Hui Peng Chang Kai Tao Source Type: research
Overexpression of ZNF169 promotes the growth and proliferation of colorectal cancer cells via the upregulation of ANKZF1
Oncol Rep. 2024 Jun;51(6):82. doi: 10.3892/or.2024.8741. Epub 2024 Apr 26.ABSTRACTColorectal cancer (CRC) is one of the most common malignancies worldwide. The 5‑year survival rate of patients diagnosed with the early stages of the disease is markedly higher than that of patients in the advanced stages. Therefore, identifying novel biomarkers and drug targets for CRC is critical for clinical practice. Zinc finger protein 169 (ZNF169) is a crucial transcription factor, and its role in CRC remains to be explored. The present study aimed to investigate the clinical relevance, function and underlying mechanisms of ZNF169 in ...
Source: Oncology Reports - April 26, 2024 Category: Cancer & Oncology Authors: Jie Zhang Ye Wang Shiyang Hou Xiaoqian Chi Danyang Ding Mei Xue Mengqiao Zhang Jing Wang Junfang Shuai Haiying Sun Qiang Gao Chunbo Kang Source Type: research
Developing innovative strategies of tumor ‑infiltrating lymphocyte therapy for tumor treatment
Oncol Rep. 2024 Jun;51(6):85. doi: 10.3892/or.2024.8744. Epub 2024 Apr 26.ABSTRACTCancer is the main cause of global mortality, and thus far, effective therapeutic strategies for cancer treatment are in high demand. Adoptive transfer of tumor‑infiltrating lymphocytes (TILs) represents a promising avenue in immunotherapy for the management of malignancies. The clinical safety and efficacy of TIL‑based therapy have been established through numerous rigorous clinical trials. However, the efficacy of TIL infusion in inducing an anti‑tumor response is limited to a subset of clinical patients with cancer. Therefore, there ...
Source: Oncology Reports - April 26, 2024 Category: Cancer & Oncology Authors: Zhongjie Yu Jianhua Shi Yuan Fang Yi Zhao Aotian Xu Ning Li Source Type: research
Important role and underlying mechanism of non ‑SMC condensin I complex subunit G in tumours (Review)
Oncol Rep. 2024 Jun;51(6):77. doi: 10.3892/or.2024.8736. Epub 2024 Apr 19.ABSTRACTAt present, the incidence of tumours is increasing on a yearly basis, and tumourigenesis is usually associated with chromosomal instability and cell cycle dysregulation. Moreover, abnormalities in the chromosomal structure often lead to DNA damage, further exacerbating gene mutations and chromosomal rearrangements. However, the non‑SMC condensin I complex subunit G (NCAPG) of the structural maintenance of chromosomes family is known to exert a key role in tumour development. It has been shown that high expression of NCAPG is closely associa...
Source: Oncology Reports - April 19, 2024 Category: Cancer & Oncology Authors: Ruobing Li Dechun Wang Hong Yang Leilei Pu Xiaohong Li Fumei Yang Rong Zhu Source Type: research
[Corrigendum] Long non ‑coding RNA H19 regulates LASP1 expression in osteosarcoma by competitively binding to miR‑29a‑3p
Oncol Rep. 2024 Jun;51(6):78. doi: 10.3892/or.2024.8737. Epub 2024 Apr 19.ABSTRACTFollowing the publication of the above article, an interested reader drew to the authors' attention that, for the cell invasion assay experiments shown in Fig. 2D on p. 5, there appeared to be an overlapping section of data comparing between the Sao‑2/Control and MG‑63/siH19 panels, such that these data had been derived from the same original source where the panels were intended to portray the results from differently performed epxeriments. Upon examining their original data, the authors have realized that, in Fig. 2D, an inadvertent err...
Source: Oncology Reports - April 19, 2024 Category: Cancer & Oncology Authors: Hao Jin Huan Wang Xin Jin Wenbo Wang Source Type: research
[Corrigendum] Cripto ‑1 promotes epithelial‑mesenchymal transition in prostate cancer via Wnt/β‑catenin signaling
Oncol Rep. 2024 Jun;51(6):75. doi: 10.3892/or.2024.8734. Epub 2024 Apr 19.ABSTRACTFollowing the publication of the above article, an interested reader drew to the authors' attention that the β‑actin control blots featured in Figs. 5A and 6A appeared to be strikingly similar. Upon examining their original data, the authors have realized that the β‑actin blots for Fig. 5A were inadvertently chosen incorrectly. The corrected version of Fig. 5 is shown opposite. Note that the error made in uploading the incorrect version of this figure did not affect the overall conclusions reported in the paper. All the authors agree wi...
Source: Oncology Reports - April 19, 2024 Category: Cancer & Oncology Authors: Yan Liu Zhenbang Qin Kuo Yang Ranlu Liu Yong Xu Source Type: research
Cetuximab chemotherapy resistance: Insight into the homeostatic evolution of head and neck cancer (Review)
Oncol Rep. 2024 Jun;51(6):80. doi: 10.3892/or.2024.8739. Epub 2024 Apr 19.ABSTRACTThe complex evolution of genetic alterations in cancer that occurs in vivo is a selective process involving numerous factors and mechanisms. Chemotherapeutic agents that prevent the growth and spread of cancer cells induce selective pressure, leading to rapid artificial selection of resistant subclones. This rapid evolution is possible because antineoplastic drugs promote alterations in tumor‑cell metabolism, thus creating a bottleneck event. The few resistant cells that survive in this new environment obtain differential reproductive succe...
Source: Oncology Reports - April 19, 2024 Category: Cancer & Oncology Authors: Carlos Henrique De Paula Diniz Tiago Henrique Ana Carolina B Stefanini Tialfi Bergamin De Castro Eloiza H Tajara Source Type: research
The role of ferroptosis in radiotherapy and combination therapy for head and neck squamous cell carcinoma (Review)
Oncol Rep. 2024 Jun;51(6):79. doi: 10.3892/or.2024.8738. Epub 2024 Apr 19.ABSTRACTHead and neck squamous cell carcinoma (HNSCC) is a highly aggressive, heterogeneous tumour usually caused by alcohol and tobacco consumption, making it one of the most common malignancies worldwide. Despite the fact that various therapeutic approaches such as surgery, radiation therapy (RT), chemotherapy (CT) and targeted therapy have been widely used for HNSCC in recent years, its recurrence rate and mortality rate remain high. RT is the standard treatment choice for HNSCC, which induces reactive oxygen species production and causes oxidativ...
Source: Oncology Reports - April 19, 2024 Category: Cancer & Oncology Authors: Yu Feng Xiulei Li Bingwu Yang Maocai Li Yongya Du Jing Wang Siyu Liu Lili Gong Lianqing Li Lei Gao Source Type: research
[Retracted] Tissue ‑specific transplantation antigen P35B functions as an oncogene and is regulated by microRNA‑125a‑5p in lung cancer
Oncol Rep. 2024 Jun;51(6):76. doi: 10.3892/or.2024.8735. Epub 2024 Apr 19.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the immunohistochemical data shown in Fig. 1A on p. 5, colony formation data shown in Figs. 2C, H and M and 6D on p. 6 and p. 10 respectively, the western blots in Fig. 2B, Transwell cell migration and invasion assay data in Fig. 3B, D and F, and immunofluorescence data in Fig. 4C had already appeared in previously published articles written by different authors at different research institutes (some of which have subsequently...
Source: Oncology Reports - April 19, 2024 Category: Cancer & Oncology Authors: Yingjie Gao Guangliang Zhang Jinlong Liu Huimin Li Source Type: research
Important role and underlying mechanism of non ‑SMC condensin I complex subunit G in tumours (Review)
Oncol Rep. 2024 Jun;51(6):77. doi: 10.3892/or.2024.8736. Epub 2024 Apr 19.ABSTRACTAt present, the incidence of tumours is increasing on a yearly basis, and tumourigenesis is usually associated with chromosomal instability and cell cycle dysregulation. Moreover, abnormalities in the chromosomal structure often lead to DNA damage, further exacerbating gene mutations and chromosomal rearrangements. However, the non‑SMC condensin I complex subunit G (NCAPG) of the structural maintenance of chromosomes family is known to exert a key role in tumour development. It has been shown that high expression of NCAPG is closely associa...
Source: Oncology Reports - April 19, 2024 Category: Cancer & Oncology Authors: Ruobing Li Dechun Wang Hong Yang Leilei Pu Xiaohong Li Fumei Yang Rong Zhu Source Type: research
[Corrigendum] Long non ‑coding RNA H19 regulates LASP1 expression in osteosarcoma by competitively binding to miR‑29a‑3p
Oncol Rep. 2024 Jun;51(6):78. doi: 10.3892/or.2024.8737. Epub 2024 Apr 19.ABSTRACTFollowing the publication of the above article, an interested reader drew to the authors' attention that, for the cell invasion assay experiments shown in Fig. 2D on p. 5, there appeared to be an overlapping section of data comparing between the Sao‑2/Control and MG‑63/siH19 panels, such that these data had been derived from the same original source where the panels were intended to portray the results from differently performed epxeriments. Upon examining their original data, the authors have realized that, in Fig. 2D, an inadvertent err...
Source: Oncology Reports - April 19, 2024 Category: Cancer & Oncology Authors: Hao Jin Huan Wang Xin Jin Wenbo Wang Source Type: research
[Corrigendum] Cripto ‑1 promotes epithelial‑mesenchymal transition in prostate cancer via Wnt/β‑catenin signaling
Oncol Rep. 2024 Jun;51(6):75. doi: 10.3892/or.2024.8734. Epub 2024 Apr 19.ABSTRACTFollowing the publication of the above article, an interested reader drew to the authors' attention that the β‑actin control blots featured in Figs. 5A and 6A appeared to be strikingly similar. Upon examining their original data, the authors have realized that the β‑actin blots for Fig. 5A were inadvertently chosen incorrectly. The corrected version of Fig. 5 is shown opposite. Note that the error made in uploading the incorrect version of this figure did not affect the overall conclusions reported in the paper. All the authors agree wi...
Source: Oncology Reports - April 19, 2024 Category: Cancer & Oncology Authors: Yan Liu Zhenbang Qin Kuo Yang Ranlu Liu Yong Xu Source Type: research
Cetuximab chemotherapy resistance: Insight into the homeostatic evolution of head and neck cancer (Review)
Oncol Rep. 2024 Jun;51(6):80. doi: 10.3892/or.2024.8739. Epub 2024 Apr 19.ABSTRACTThe complex evolution of genetic alterations in cancer that occurs in vivo is a selective process involving numerous factors and mechanisms. Chemotherapeutic agents that prevent the growth and spread of cancer cells induce selective pressure, leading to rapid artificial selection of resistant subclones. This rapid evolution is possible because antineoplastic drugs promote alterations in tumor‑cell metabolism, thus creating a bottleneck event. The few resistant cells that survive in this new environment obtain differential reproductive succe...
Source: Oncology Reports - April 19, 2024 Category: Cancer & Oncology Authors: Carlos Henrique De Paula Diniz Tiago Henrique Ana Carolina B Stefanini Tialfi Bergamin De Castro Eloiza H Tajara Source Type: research
