[Corrigendum] Induction of microRNA ‑let‑7a inhibits lung adeno-carcinoma cell growth by regulating cyclin D1
Oncol Rep. 2024 May;51(5):62. doi: 10.3892/or.2024.8721. Epub 2024 Mar 8.ABSTRACTAfter the publication of the article, an interested reader drew to the authors' attention that, in the western blots shown in Fig. 5C and D, a pair of data panels were inadvertently duplicated comparing between panels (C) and (D); in addition, the cell migration data shown in Fig. 7F on p. 1852 were selected incorrectly. The authors have examined their original data, and realize that these errors arose inadvertently as a consequence of their mishandling of their data. The revised versions of Figs. 5 and 7, featuring the corrected data for the ...
Source: Oncology Reports - March 8, 2024 Category: Cancer & Oncology Authors: Wei Zhao Jin-Xia Hu Rui-Min Hao Qian Zhang Jun-Qi Guo You-Jie Li Ning Xie Lu-Ying Liu Ping-Yu Wang Can Zhang Shu-Yang Xie Source Type: research

Current and future perspectives in unresectable locally advanced esophageal squamous cell cancer (Review)
Oncol Rep. 2024 May;51(5):65. doi: 10.3892/or.2024.8724. Epub 2024 Mar 8.ABSTRACTDefinitive concurrent chemoradiotherapy has been the main standard treatment method for unresectable locally advanced esophageal squamous cell cancer (ESCC) since 1999. However, several disadvantages continue to be associated with this type of treatment, including a high local failure rate (reaching ~50% within 3 years) and a median overall survival (OS) time of 16.9 months. In addition, the 5‑year overall survival rate of patients remains relatively low, at only ~21% for patients with ESCC with TNM stage T1‑3N0‑1M0. Burgeoning clinical ...
Source: Oncology Reports - March 8, 2024 Category: Cancer & Oncology Authors: Weijia Zhang Min Zhu Ying Xiang Yujiao Sun Shuang Li Jun Cai Hai Zeng Source Type: research

Unveiling the best predictive models for early ‑onset metastatic cancer: Insights and innovations (Review)
In conclusion, the present review underscored the importance of early detection and management of metastatic types of cancer and called for improved predictive models, including advanced techniques such as nomograms and machine learning, so as to enhance patient outcomes, acknowledging the challenges and limitations of the current research as well as the necessity for further studies.PMID:38456540 | DOI:10.3892/or.2024.8719 (Source: Oncology Reports)
Source: Oncology Reports - March 8, 2024 Category: Cancer & Oncology Authors: Liqing Yu Zhenjun Huang Ziqi Xiao Xiaofu Tang Ziqiang Zeng Xiaoli Tang Wenhao Ouyang Source Type: research

α‑Phellandrene enhances the apoptosis of HT‑29 cells induced by 5‑fluorouracil by modulating the mitochondria‑dependent pathway
Oncol Rep. 2024 Apr;51(4):61. doi: 10.3892/or.2024.8720. Epub 2024 Mar 8.ABSTRACTα‑Phellandrene (α‑PA), a natural constituent of herbs, inhibits cancer cell viability and proliferation. 5‑Fluorouracil (5‑FU) is a frequently utilized chemotherapeutic medicine for the treatment of colon cancer, which works by triggering cancer cell apoptosis. The present study examined how the combination of α‑PA and 5‑FU affects the suppression of human colon cancer cells by promoting apoptosis. The impact of this treatment on cell viability, apoptosis, and the expression levels of Bcl‑2 family members, caspase family membe...
Source: Oncology Reports - March 8, 2024 Category: Cancer & Oncology Authors: Anita Caroline Susanto Laksmi Hartajanie Chih-Chung Wu Source Type: research

MITF regulates the subcellular location of HIF1 α through SUMOylation to promote the invasion and metastasis of daughter cells derived from polyploid giant cancer cells
In conclusion, the post‑translation modification regulated the subcellular location of HIF1α and the nuclear expression of HIF1α promoted the proliferation, migration and invasion abilities of PDCs. MITF could regulate the transcription and protein levels of HIF1α and participate in the regulation of HIF1α SUMOylation.PMID:38456491 | DOI:10.3892/or.2024.8722 (Source: Oncology Reports)
Source: Oncology Reports - March 8, 2024 Category: Cancer & Oncology Authors: Minying Zheng Shifeng Tian Xinyue Zhou Man Yan Mingming Zhou Yongjun Yu Yue Zhang Xiaorui Wang Na Li Li Ren Shiwu Zhang Source Type: research

[Retracted] MicroRNA ‑140 represses glioma growth and metastasis by directly targeting ADAM9
Oncol Rep. 2024 May;51(5):64. doi: 10.3892/or.2024.8723. Epub 2024 Mar 8.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the Transwell cell invasion and migration assay data shown in Figs. 2C and 5D were strikingly similar to data in different form in other articles written by different authors at different research institutes, which had either already been published or had been submitted for publication at around the same time (some of which have now been retracted). Owing to the fact that certain of the data in the above article had already bee...
Source: Oncology Reports - March 8, 2024 Category: Cancer & Oncology Authors: Xiaogang Liu Shanjun Wang Aiqin Yuan Xunhui Yuan Bing Liu Source Type: research

[Corrigendum] Induction of microRNA ‑let‑7a inhibits lung adeno-carcinoma cell growth by regulating cyclin D1
Oncol Rep. 2024 May;51(5):62. doi: 10.3892/or.2024.8721. Epub 2024 Mar 8.ABSTRACTAfter the publication of the article, an interested reader drew to the authors' attention that, in the western blots shown in Fig. 5C and D, a pair of data panels were inadvertently duplicated comparing between panels (C) and (D); in addition, the cell migration data shown in Fig. 7F on p. 1852 were selected incorrectly. The authors have examined their original data, and realize that these errors arose inadvertently as a consequence of their mishandling of their data. The revised versions of Figs. 5 and 7, featuring the corrected data for the ...
Source: Oncology Reports - March 8, 2024 Category: Cancer & Oncology Authors: Wei Zhao Jin-Xia Hu Rui-Min Hao Qian Zhang Jun-Qi Guo You-Jie Li Ning Xie Lu-Ying Liu Ping-Yu Wang Can Zhang Shu-Yang Xie Source Type: research

Current and future perspectives in unresectable locally advanced esophageal squamous cell cancer (Review)
Oncol Rep. 2024 May;51(5):65. doi: 10.3892/or.2024.8724. Epub 2024 Mar 8.ABSTRACTDefinitive concurrent chemoradiotherapy has been the main standard treatment method for unresectable locally advanced esophageal squamous cell cancer (ESCC) since 1999. However, several disadvantages continue to be associated with this type of treatment, including a high local failure rate (reaching ~50% within 3 years) and a median overall survival (OS) time of 16.9 months. In addition, the 5‑year overall survival rate of patients remains relatively low, at only ~21% for patients with ESCC with TNM stage T1‑3N0‑1M0. Burgeoning clinical ...
Source: Oncology Reports - March 8, 2024 Category: Cancer & Oncology Authors: Weijia Zhang Min Zhu Ying Xiang Yujiao Sun Shuang Li Jun Cai Hai Zeng Source Type: research

Unveiling the best predictive models for early ‑onset metastatic cancer: Insights and innovations (Review)
In conclusion, the present review underscored the importance of early detection and management of metastatic types of cancer and called for improved predictive models, including advanced techniques such as nomograms and machine learning, so as to enhance patient outcomes, acknowledging the challenges and limitations of the current research as well as the necessity for further studies.PMID:38456540 | DOI:10.3892/or.2024.8719 (Source: Oncology Reports)
Source: Oncology Reports - March 8, 2024 Category: Cancer & Oncology Authors: Liqing Yu Zhenjun Huang Ziqi Xiao Xiaofu Tang Ziqiang Zeng Xiaoli Tang Wenhao Ouyang Source Type: research

α‑Phellandrene enhances the apoptosis of HT‑29 cells induced by 5‑fluorouracil by modulating the mitochondria‑dependent pathway
Oncol Rep. 2024 Apr;51(4):61. doi: 10.3892/or.2024.8720. Epub 2024 Mar 8.ABSTRACTα‑Phellandrene (α‑PA), a natural constituent of herbs, inhibits cancer cell viability and proliferation. 5‑Fluorouracil (5‑FU) is a frequently utilized chemotherapeutic medicine for the treatment of colon cancer, which works by triggering cancer cell apoptosis. The present study examined how the combination of α‑PA and 5‑FU affects the suppression of human colon cancer cells by promoting apoptosis. The impact of this treatment on cell viability, apoptosis, and the expression levels of Bcl‑2 family members, caspase family membe...
Source: Oncology Reports - March 8, 2024 Category: Cancer & Oncology Authors: Anita Caroline Susanto Laksmi Hartajanie Chih-Chung Wu Source Type: research

MITF regulates the subcellular location of HIF1 α through SUMOylation to promote the invasion and metastasis of daughter cells derived from polyploid giant cancer cells
In conclusion, the post‑translation modification regulated the subcellular location of HIF1α and the nuclear expression of HIF1α promoted the proliferation, migration and invasion abilities of PDCs. MITF could regulate the transcription and protein levels of HIF1α and participate in the regulation of HIF1α SUMOylation.PMID:38456491 | DOI:10.3892/or.2024.8722 (Source: Oncology Reports)
Source: Oncology Reports - March 8, 2024 Category: Cancer & Oncology Authors: Minying Zheng Shifeng Tian Xinyue Zhou Man Yan Mingming Zhou Yongjun Yu Yue Zhang Xiaorui Wang Na Li Li Ren Shiwu Zhang Source Type: research

[Retracted] MicroRNA ‑140 represses glioma growth and metastasis by directly targeting ADAM9
Oncol Rep. 2024 May;51(5):64. doi: 10.3892/or.2024.8723. Epub 2024 Mar 8.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the Transwell cell invasion and migration assay data shown in Figs. 2C and 5D were strikingly similar to data in different form in other articles written by different authors at different research institutes, which had either already been published or had been submitted for publication at around the same time (some of which have now been retracted). Owing to the fact that certain of the data in the above article had already bee...
Source: Oncology Reports - March 8, 2024 Category: Cancer & Oncology Authors: Xiaogang Liu Shanjun Wang Aiqin Yuan Xunhui Yuan Bing Liu Source Type: research

[Corrigendum] Induction of microRNA ‑let‑7a inhibits lung adeno-carcinoma cell growth by regulating cyclin D1
Oncol Rep. 2024 May;51(5):62. doi: 10.3892/or.2024.8721. Epub 2024 Mar 8.ABSTRACTAfter the publication of the article, an interested reader drew to the authors' attention that, in the western blots shown in Fig. 5C and D, a pair of data panels were inadvertently duplicated comparing between panels (C) and (D); in addition, the cell migration data shown in Fig. 7F on p. 1852 were selected incorrectly. The authors have examined their original data, and realize that these errors arose inadvertently as a consequence of their mishandling of their data. The revised versions of Figs. 5 and 7, featuring the corrected data for the ...
Source: Oncology Reports - March 8, 2024 Category: Cancer & Oncology Authors: Wei Zhao Jin-Xia Hu Rui-Min Hao Qian Zhang Jun-Qi Guo You-Jie Li Ning Xie Lu-Ying Liu Ping-Yu Wang Can Zhang Shu-Yang Xie Source Type: research

Current and future perspectives in unresectable locally advanced esophageal squamous cell cancer (Review)
Oncol Rep. 2024 May;51(5):65. doi: 10.3892/or.2024.8724. Epub 2024 Mar 8.ABSTRACTDefinitive concurrent chemoradiotherapy has been the main standard treatment method for unresectable locally advanced esophageal squamous cell cancer (ESCC) since 1999. However, several disadvantages continue to be associated with this type of treatment, including a high local failure rate (reaching ~50% within 3 years) and a median overall survival (OS) time of 16.9 months. In addition, the 5‑year overall survival rate of patients remains relatively low, at only ~21% for patients with ESCC with TNM stage T1‑3N0‑1M0. Burgeoning clinical ...
Source: Oncology Reports - March 8, 2024 Category: Cancer & Oncology Authors: Weijia Zhang Min Zhu Ying Xiang Yujiao Sun Shuang Li Jun Cai Hai Zeng Source Type: research

Unveiling the best predictive models for early ‑onset metastatic cancer: Insights and innovations (Review)
In conclusion, the present review underscored the importance of early detection and management of metastatic types of cancer and called for improved predictive models, including advanced techniques such as nomograms and machine learning, so as to enhance patient outcomes, acknowledging the challenges and limitations of the current research as well as the necessity for further studies.PMID:38456540 | DOI:10.3892/or.2024.8719 (Source: Oncology Reports)
Source: Oncology Reports - March 8, 2024 Category: Cancer & Oncology Authors: Liqing Yu Zhenjun Huang Ziqi Xiao Xiaofu Tang Ziqiang Zeng Xiaoli Tang Wenhao Ouyang Source Type: research