m6A methyltransferase METTL14 ‑mediated RP1‑228H13.5 promotes the occurrence of liver cancer by targeting hsa‑miR‑205/ZIK1
Oncol Rep. 2024 Apr;51(4):59. doi: 10.3892/or.2024.8718. Epub 2024 Mar 1.ABSTRACTThe aim of the present study was to explore the association between N6‑methyladenosine (m6A) modification regulatory gene‑related long noncoding (lnc)RNA RP1‑228H13.5 and cancer prognosis through bioinformatics analysis, as well as the impact of RP1‑228H13.5 on cell biology‑related behaviors and specific molecular mechanisms. Bioinformatics analysis was used to construct a risk model consisting of nine genes. This model can reflect the survival time and differentiation degree of cancer. Subsequently, a competing endogenous RNA networ...
Source: Oncology Reports - March 1, 2024 Category: Cancer & Oncology Authors: Jia Xu Chang Liu Kai Qu Jingyao Zhang Sinan Liu Fandi Meng Yong Wan Source Type: research

[Retracted] Downregulation of microRNA-206 suppresses clear cell renal carcinoma proliferation and invasion by targeting vascular endothelial growth factor  A
Oncol Rep. 2024 Apr;51(4):58. doi: 10.3892/or.2024.8717. Epub 2024 Mar 1.ABSTRACTFollowing the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that there appeared to be several instances of overlapping data panels comparing between the Transwell invasion and migration assay images shown in Figs. 2E and 4G, such that data which were intended to show the results from differently performed experiments were apparently derived from a (much) smaller number of original sources. Given the number of cases of overlapping data panels both within and between this pair of figures in the arti...
Source: Oncology Reports - March 1, 2024 Category: Cancer & Oncology Authors: Yi Cai Hanzhong Li Yushi Zhang Source Type: research

Effect of hypoxia ‑HIF‑1α‑periostin axis in thyroid cancer
Oncol Rep. 2024 Apr;51(4):57. doi: 10.3892/or.2024.8716. Epub 2024 Feb 23.ABSTRACTThe incidence of thyroid carcinoma (TC) has exhibited a rapid increase in recent years. A proportion of TCs exhibit aggressive behavior. The present study aimed to investigate the potential role of hypoxia‑hypoxia inducible factor 1 subunit α (HIF‑1α)‑periostin axis in the progression of TC. The upregulation of periostin and HIF‑1α expression levels was detected in 95 clinical TC tissues as compared with normal thyroid tissues. Hypoxia promoted the viability and invasion of TC cells and this effect was inhibited by the downregulati...
Source: Oncology Reports - February 23, 2024 Category: Cancer & Oncology Authors: Ye Yang Junyi Wu Huiqin Zhu Xiaoqin Shi Jun Liu Yang Li Min Wang Source Type: research

[Retracted] MicroRNA ‑362 is downregulated in cervical cancer and inhibits cell proliferation, migration and invasion by directly targeting SIX1
Oncol Rep. 2024 Apr;51(4):54. doi: 10.3892/or.2024.8713. Epub 2024 Feb 9.ABSTRACTFollowing the publication of the above article, a concerned reader drew to the Editor's attention that the Transwell cell migration and invasion assay data featured in Fig. 2C were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes that had either already been published elsewhere prior to the submission of this paper to Oncology Reports, or were under consideration for publication at around the same time (some of which have been retracted). Furthermore, a numbe...
Source: Oncology Reports - February 9, 2024 Category: Cancer & Oncology Authors: Can Shi Zhenyu Zhang Source Type: research

Advances in research and application of photodynamic therapy in cholangiocarcinoma (Review)
Oncol Rep. 2024 Mar;51(3):53. doi: 10.3892/or.2024.8712. Epub 2024 Feb 9.ABSTRACTCholangiocarcinoma (CCA) is a disease characterized by insidious clinical manifestations and challenging to diagnose. Patients are usually diagnosed at an advanced stage and miss the opportunity for radical surgery. Therefore, effective palliative therapy is the main treatment approach for unresectable CCA. Current common palliative treatments include biliary drainage, chemotherapy, radiotherapy, targeted therapy and immunotherapy. However, these treatments only offer limited improvement in quality of life and survival. Photodynamic therapy (P...
Source: Oncology Reports - February 9, 2024 Category: Cancer & Oncology Authors: Yufeng Li Yuhang Li Yinghui Song Sulai Liu Source Type: research

[Retracted] MicroRNA ‑362 is downregulated in cervical cancer and inhibits cell proliferation, migration and invasion by directly targeting SIX1
Oncol Rep. 2024 Apr;51(4):54. doi: 10.3892/or.2024.8713. Epub 2024 Feb 9.ABSTRACTFollowing the publication of the above article, a concerned reader drew to the Editor's attention that the Transwell cell migration and invasion assay data featured in Fig. 2C were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes that had either already been published elsewhere prior to the submission of this paper to Oncology Reports, or were under consideration for publication at around the same time (some of which have been retracted). Furthermore, a numbe...
Source: Oncology Reports - February 9, 2024 Category: Cancer & Oncology Authors: Can Shi Zhenyu Zhang Source Type: research

Advances in research and application of photodynamic therapy in cholangiocarcinoma (Review)
Oncol Rep. 2024 Mar;51(3):53. doi: 10.3892/or.2024.8712. Epub 2024 Feb 9.ABSTRACTCholangiocarcinoma (CCA) is a disease characterized by insidious clinical manifestations and challenging to diagnose. Patients are usually diagnosed at an advanced stage and miss the opportunity for radical surgery. Therefore, effective palliative therapy is the main treatment approach for unresectable CCA. Current common palliative treatments include biliary drainage, chemotherapy, radiotherapy, targeted therapy and immunotherapy. However, these treatments only offer limited improvement in quality of life and survival. Photodynamic therapy (P...
Source: Oncology Reports - February 9, 2024 Category: Cancer & Oncology Authors: Yufeng Li Yuhang Li Yinghui Song Sulai Liu Source Type: research

[Retracted] MicroRNA ‑362 is downregulated in cervical cancer and inhibits cell proliferation, migration and invasion by directly targeting SIX1
Oncol Rep. 2024 Apr;51(4):54. doi: 10.3892/or.2024.8713. Epub 2024 Feb 9.ABSTRACTFollowing the publication of the above article, a concerned reader drew to the Editor's attention that the Transwell cell migration and invasion assay data featured in Fig. 2C were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes that had either already been published elsewhere prior to the submission of this paper to Oncology Reports, or were under consideration for publication at around the same time (some of which have been retracted). Furthermore, a numbe...
Source: Oncology Reports - February 9, 2024 Category: Cancer & Oncology Authors: Can Shi Zhenyu Zhang Source Type: research

Advances in research and application of photodynamic therapy in cholangiocarcinoma (Review)
Oncol Rep. 2024 Mar;51(3):53. doi: 10.3892/or.2024.8712. Epub 2024 Feb 9.ABSTRACTCholangiocarcinoma (CCA) is a disease characterized by insidious clinical manifestations and challenging to diagnose. Patients are usually diagnosed at an advanced stage and miss the opportunity for radical surgery. Therefore, effective palliative therapy is the main treatment approach for unresectable CCA. Current common palliative treatments include biliary drainage, chemotherapy, radiotherapy, targeted therapy and immunotherapy. However, these treatments only offer limited improvement in quality of life and survival. Photodynamic therapy (P...
Source: Oncology Reports - February 9, 2024 Category: Cancer & Oncology Authors: Yufeng Li Yuhang Li Yinghui Song Sulai Liu Source Type: research

[Retracted] MicroRNA ‑362 is downregulated in cervical cancer and inhibits cell proliferation, migration and invasion by directly targeting SIX1
Oncol Rep. 2024 Apr;51(4):54. doi: 10.3892/or.2024.8713. Epub 2024 Feb 9.ABSTRACTFollowing the publication of the above article, a concerned reader drew to the Editor's attention that the Transwell cell migration and invasion assay data featured in Fig. 2C were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes that had either already been published elsewhere prior to the submission of this paper to Oncology Reports, or were under consideration for publication at around the same time (some of which have been retracted). Furthermore, a numbe...
Source: Oncology Reports - February 9, 2024 Category: Cancer & Oncology Authors: Can Shi Zhenyu Zhang Source Type: research