[Corrigendum] Saffron carotenoids inhibit STAT3 activation and promote apoptotic progression in IL ‑6‑stimulated liver cancer cells
Oncol Rep. 2024 May;51(5):68. doi: 10.3892/or.2024.8727. Epub 2024 Mar 29.ABSTRACTFollowing the publication of the above article, an interested reader drew to the authors' attention that, in Fig. 1E on p. 1885, the STAT3 blots shown for the A549 and A2780 cell lines were strikingly similar, such that these data were possibly derived from the same original source where the panels were intended to show the results from differently performed experiments. Upon examining their original data, the authors have realized that an inadvertent error was made in assembling the data in the figure, and the STAT3 data shown correctly for ...
Source: Oncology Reports - March 29, 2024 Category: Cancer & Oncology Authors: Buyun Kim Byoungduck Park Source Type: research
LPCAT1 promotes melanoma cell proliferation via Akt signaling
Oncol Rep. 2024 May;51(5):67. doi: 10.3892/or.2024.8726. Epub 2024 Mar 29.ABSTRACTMelanoma is the most lethal type of skin cancer with an increasing cutaneous cancer‑related mortality rate worldwide. Despite therapeutic advances in targeted therapy and immunotherapy, the overall survival of patients with melanoma remains unsatisfactory. Thus, a further understanding of the pathogenesis of melanoma may aid towards the development of therapeutic strategies. Lysophosphatidylcholine acyltransferase 1 (LPCAT1) is a key enzyme that converts lysophosphatidylcholine into phosphatidylcholine in lipid remodeling. In the present st...
Source: Oncology Reports - March 29, 2024 Category: Cancer & Oncology Authors: Yuqian Wang Yingjian Huang Yan Wang Wen Zhang Ning Wang Ruimin Bai Ruiting Luo Huihui Tuo Yan Zheng Source Type: research
[Corrigendum] Saffron carotenoids inhibit STAT3 activation and promote apoptotic progression in IL ‑6‑stimulated liver cancer cells
Oncol Rep. 2024 May;51(5):68. doi: 10.3892/or.2024.8727. Epub 2024 Mar 29.ABSTRACTFollowing the publication of the above article, an interested reader drew to the authors' attention that, in Fig. 1E on p. 1885, the STAT3 blots shown for the A549 and A2780 cell lines were strikingly similar, such that these data were possibly derived from the same original source where the panels were intended to show the results from differently performed experiments. Upon examining their original data, the authors have realized that an inadvertent error was made in assembling the data in the figure, and the STAT3 data shown correctly for ...
Source: Oncology Reports - March 29, 2024 Category: Cancer & Oncology Authors: Buyun Kim Byoungduck Park Source Type: research
[Retracted] Tanshinone IIA enhances the inhibitory effect of imatinib on proliferation and motility of acute leukemia cell line TIB ‑152 < em > in vivo < /em > and < em > in vitro < /em > by inhibiting the PI3K/AKT/mTOR signaling pathway
Oncol Rep. 2024 May;51(5):66. doi: 10.3892/or.2024.8725. Epub 2024 Mar 15.ABSTRACTFollowing the publication of the above article, a concerned reader drew to the Editor's attention that the Transwell cell invasion assay data featured in Figs. 2D and 4E, certain of the tumor images in Fig. 5A and the TUNEL assay data in Fig. 5C were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes that had either already been published elsewhere prior to the submission of this paper to Oncology Reports, or which under consideration for publication at around...
Source: Oncology Reports - March 15, 2024 Category: Cancer & Oncology Authors: Zhi Teng Shijuan Xu Qin Lei Source Type: research
[Retracted] Tanshinone IIA enhances the inhibitory effect of imatinib on proliferation and motility of acute leukemia cell line TIB ‑152 < em > in vivo < /em > and < em > in vitro < /em > by inhibiting the PI3K/AKT/mTOR signaling pathway
Oncol Rep. 2024 May;51(5):66. doi: 10.3892/or.2024.8725. Epub 2024 Mar 15.ABSTRACTFollowing the publication of the above article, a concerned reader drew to the Editor's attention that the Transwell cell invasion assay data featured in Figs. 2D and 4E, certain of the tumor images in Fig. 5A and the TUNEL assay data in Fig. 5C were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes that had either already been published elsewhere prior to the submission of this paper to Oncology Reports, or which under consideration for publication at around...
Source: Oncology Reports - March 15, 2024 Category: Cancer & Oncology Authors: Zhi Teng Shijuan Xu Qin Lei Source Type: research
α‑Phellandrene enhances the apoptosis of HT‑29 cells induced by 5‑fluorouracil by modulating the mitochondria‑dependent pathway
Oncol Rep. 2024 Apr;51(4):61. doi: 10.3892/or.2024.8720. Epub 2024 Mar 8.ABSTRACTα‑Phellandrene (α‑PA), a natural constituent of herbs, inhibits cancer cell viability and proliferation. 5‑Fluorouracil (5‑FU) is a frequently utilized chemotherapeutic medicine for the treatment of colon cancer, which works by triggering cancer cell apoptosis. The present study examined how the combination of α‑PA and 5‑FU affects the suppression of human colon cancer cells by promoting apoptosis. The impact of this treatment on cell viability, apoptosis, and the expression levels of Bcl‑2 family members, caspase family membe...
Source: Oncology Reports - March 8, 2024 Category: Cancer & Oncology Authors: Anita Caroline Susanto Laksmi Hartajanie Chih-Chung Wu Source Type: research
