The efficacy of a single-session pro-yellow laser in the treatment of facial telangiectasia
AbstractFacial telangiectasia (FT) is a condition in which small dilated vessels visibly protrude on the surface of the skin. The aim of this study was to evaluate the efficacy and safety of a single-session pro-yellow laser in the treatment of FT and spider angioma (SA) to compare it with a limited number of studies conducted on this subject. In this pilot study, we reviewed 41 patients who admitted to our dermatology clinic with FT and SA and were treated by using pro-yellow laser. The efficacy of the treatment was evaluated using the recorded clinical information and digital camera images. The improvement was graded as ...
Source: Lasers in Medical Science - February 13, 2021 Category: Laser Surgery Source Type: research

Evaluation of bond strength of resin cement to Er:YAG laser-etched enamel and dentin after cementation of ceramic discs
AbstractThe purpose of this study was to investigate the shear bond strength (SBS) of ceramic discs luted to differently etched enamel and dentin surfaces. Occlusal surfaces of 64 carious-free human molars and vestibule surfaces of 64 first maxillary incisors were ground to get flat superficial dentin and flattened enamel respectively. After generating 4 groups according to the surface etching method (37% orthophosphoric acid, Er:YAG laser –contact handpiece/scanning handpiece (1 or 2 times of scanning)), ceramic discs were luted to the surfaces with adhesive resin cement (Variolink N, Vivadent Ets., Schaan/Liechtens...
Source: Lasers in Medical Science - February 13, 2021 Category: Laser Surgery Source Type: research

A novel high-power 1060-nm diode laser for the treatment of vascular malformations: a pilot study using dermoscopy to evaluate clinical endpoints
(Source: Lasers in Medical Science)
Source: Lasers in Medical Science - February 13, 2021 Category: Laser Surgery Source Type: research

Combined effects of photobiomodulation and curcumin on mast cells and wound strength in wound healing of streptozotocin-induced diabetes in rats
AbstractWe investigated the probable involvement of mast cell degranulation and their numbers in the remodeling step of wound healing in a diabetic ischemic skin wound model treated with photobiomodulation plus curcumin. A total of 108 adult male Wistar rats were randomized into one healthy control and five diabetic groups. Type I diabetes was inflicted in 90 of the 108 rats. After 1 month, an excisional wound was generated in each of the 108 rats. There were one healthy group (group 1) and five diabetic groups as follows: group 2 was the untreated diabetic control group and group 3 rats were treated with sesame oil. Rats ...
Source: Lasers in Medical Science - February 13, 2021 Category: Laser Surgery Source Type: research

Capillaroscopy and reflectance confocal microscopy characterization of refractory port-wine stains
AbstractPort-wine stains (PWS) are frequently refractory to laser treatments. Although previous data highlight prognostic factors and biological events related to poor outcomes, no previous publications correlate their capillaroscopic and architectural features. The aim of the present study is to describe refractory port-wine stains performing capillaroscopy and reflectance confocal microscopy (RCM) to describe their morphological and microscopic aspects. This is a prospective cohort study. All the consecutive patients with PWS poor responsive to previous treatment were included. Clinical assessment, capillaroscopy, and re...
Source: Lasers in Medical Science - February 13, 2021 Category: Laser Surgery Source Type: research

Guidelines versus evidence: what we can learn from the Australian guideline for low-level laser therapy in knee osteoarthritis? A narrative review
AbstractThis narrative review analyses the Australian Guideline (2018) for the treatment of knee osteoarthritis (KOA) developed using Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology. The Guideline recommended against the use low-level laser therapy (LLLT). Why this conclusion was reached is discussed in this review in the context of evidence provided in other systematic reviews, the latest of which was published in 2019 and which provided strong support for LLLT for knee OA. We evaluated the reference list cited for the recommendation “against” LLLT and compared this with ...
Source: Lasers in Medical Science - February 13, 2021 Category: Laser Surgery Source Type: research

Visualization of lymphatic vascular invasion in breast cancer by multiphoton microscopy
AbstractLymphatic vascular invasion (LVI) is regarded as one of the independent factors which affect the prognosis of breast cancer. Once LVI is formed, it indicates the tumor has metastasized or has the possibility of metastasis. In this work, multiphoton microscopy (MPM), which relies on the two-photon excited fluorescence (TPEF) and second harmonic generation (SHG), was applied to identify the typical morphology of LVI and also visualize the histological features of LVI. Furthermore, the pixel density of collagen fibers was extracted as a quantitative parameter to differentiate LVI from the ductal carcinoma in situ (DCI...
Source: Lasers in Medical Science - February 13, 2021 Category: Laser Surgery Source Type: research

Effectiveness of photobiomodulation in the treatment of primary burning mouth syndrome –a systematic review and meta-analysis
AbstractTo evaluate the effectiveness of photobiomodulation (PBM) on primary burning mouth syndrome (pBMS). We searched Chinese and English studies published before February 10, 2020. The databases used include PubMed, EMBASE, the Cochrane Library, Web of Science, Wanfang Database, and China National Knowledge Infrastructure (CNKI). Randomized controlled clinical trials (RCTs) that used the PBM to treat pBMS and reported specific treatment outcomes were considered for inclusion. We eventually included 12 RCTs, and 574 samples were included in these studies. The primary outcomes investigated were pain reduction and life qua...
Source: Lasers in Medical Science - February 13, 2021 Category: Laser Surgery Source Type: research

Closure of macular hole secondary to ischemic hemi-central retinal vein occlusion by retinal photocoagulation and topical anti-inflammatory treatment
(Source: Lasers in Medical Science)
Source: Lasers in Medical Science - February 13, 2021 Category: Laser Surgery Source Type: research

Correction to: Photobiomodulation effect on children ’s scars
A Correction to this paper has been published:https://doi.org/10.1007/s10103-020-03194-w (Source: Lasers in Medical Science)
Source: Lasers in Medical Science - February 13, 2021 Category: Laser Surgery Source Type: research

Evaluation of gingival displacement methods in terms of periodontal health at crown restorations produced by digital scan: 1-year clinical follow-up
This study included 60 mandibular 1st molars from 52 participants (20 males and 32 females) requiring crown restoration. The margin lines of the crown preparations were placed 1 mm subgingivally. Based on the gingival displacement technique used, the patients were divided into three groups: retraction cord, cordless paste system, and Er,Cr:YSGG laser troughing. A digital scan of the prepared tooth was performed. Follow-up appointments were scheduled at five different times: 1st day, 1st month, 3rd month, 6th month, and 1st year. Six periodontal indices were used to assess the periodontal health. The chi-square test was use...
Source: Lasers in Medical Science - February 10, 2021 Category: Laser Surgery Source Type: research

In vitro evaluation of physical and chemical parameters involved in aPDT of Aggregatibacter actinomycetemcomitans
AbstractPeriodontitis is an infectious disease characterized by the destruction of supporting tissues. Antimicrobial photodynamic therapy (aPDT) has been proposed as an improved method for eliminating microorganisms. Its efficiency depends on the correct use of physical and chemical parameters. Thus, these parameters and their relations were evaluated in this study with the purpose of establishing lethal conditions for combating bacterial agents. Diode lasers and light-emitting diodes (LEDs) were characterized to evaluate the absorption profile and resonance of methylene blue (MB) and toluidine blue O (TBO). The relations ...
Source: Lasers in Medical Science - February 9, 2021 Category: Laser Surgery Source Type: research

Efficacy evaluation and treatment parameter optimization for laser surgery of Ota ’s nevus based on an advanced non-equilibrium bio-tissue heat transfer model
This study was performed to better understand the laser –tissue interaction mechanism and optimize the laser wavelength and pulse duration for the laser treatment of Ota’s nevus, thereby providing the precise theoretical guidance for clinician to improve the therapeutic effect. A non-equilibrium bio-tissue heat transfer model coupled with thermo-mech anical effect for the explosive vaporization of melanin granule induced by laser heating was developed to investigate the temperature and thermal damage distribution using alexandrite (755 nm) and Nd:YAG (1064 nm) lasers with the pulse width of 10–120 ns. Cry...
Source: Lasers in Medical Science - February 8, 2021 Category: Laser Surgery Source Type: research

Analytical performance of Raman spectroscopy in assaying biochemical components in human serum
The objective of this study was to evaluate the analytical performance of Raman spectroscopy for analysis of lipid profile (total cholesterol, triglycerides, and HDL cholesterol), non-protein nitrogenous compounds (urea and creatinine), and glucose in 242 human serum samples. Models to discriminate and quantify the samples were developed using the predicted concentration by quantitative regression model based on partial least squares (PLS). The analytical error for the “leave-one-out” cross-validation based on the predicted PLS concentration was 10.5 mg/dL for total cholesterol, 21.4 mg/dL for triglyceride, 13....
Source: Lasers in Medical Science - February 3, 2021 Category: Laser Surgery Source Type: research

Erbium:YAG laser augments the penetration of cryotherapy
AbstractCryotherapy is commonly used during dermatologic practice. Several modifications such as an “add-on” to topicals or intralesional applications have been already defined to enhance efficacy. The aim of this study is to test our hypothesis that ablative laser application before cryotherapy would increase the depth of freezing.Throughout this experiment, target points received either cryo therapy alone or a combination of erbium:yttrium-aluminum garnet (erbium:YAG) laser and cryotherapy. Freezing durations of 10 (C10), 20 (C20), and 30 seconds (C30) were investigated. Erbium:YAG laser groups received equal...
Source: Lasers in Medical Science - February 2, 2021 Category: Laser Surgery Source Type: research

Novel system in vitro of classifying oral carcinogenesis based on feature extraction for gray-level co-occurrence matrix using scanned laser pico projector
In this study, GLCM feature extraction and SLPP reflex images were combined to make a small, non-staining, noninvasive classification system. According to the various image characteristics in oral carcinogenesis, SLPP reflex images better define the borders and three-dimensional structures and provide effective GLCM features such as contrast, energy, and homogeneity to classify carcinogenesis in dysplastic oral keratinocyte (DOK) and normal oral keratinocyte (NOK) cells. Moreover, it also reliably classifies highly metastatic (HSC-3) and tongue cancer (CAL-27) cells. A promising computer-aided classification system for ora...
Source: Lasers in Medical Science - February 2, 2021 Category: Laser Surgery Source Type: research

Comparative evaluation of improvement in periodontal and glycemic health status of type 2 diabetes mellitus patients after scaling and root planing with or without adjunctive use of diode laser
AbstractBackgroundPeriodontal treatment in diabetic patients reduces systemic inflammatory burden and hence should be closely coordinated with the patient ’s overall clinical diabetic management.ObjectiveTo evaluate the effectiveness of diode laser (DL) (Biolase EpicTM, 940 nm, Irvine, CA, USA) as an adjunct to scaling root and planing (SRP) on periodontal health and glycated hemoglobin (HbA1c) level of type 2 diabetes mellitus (T2DM) patients suffering from generalized chronic periodontitis (CP), currently, stage II or above/grade B or C periodontitis.Materials and methodologyAfter initial screening of 55 T2DM patie...
Source: Lasers in Medical Science - February 1, 2021 Category: Laser Surgery Source Type: research

Monitoring of the choline/lipid ratio by 1 H-MRS can be helpful for prediction and early detection of tumor response to nano-photo-thermal therapy
In conclusion, the study of choline/lipid ratio using 1H-MRS may help us estimate what ha ppens in a tumor treated by the NPTT method. Such an in vivo assessment is interestingly feasible as soon as just 1 day post-NPTT. This would undoubtedly help the oncologists make a more precise decision about treatment planning strategies.Graphical abstractMonitoring of the choline/lipid ratio by1H-MRS can be helpful for prediction and early detection of response to nano-photo-thermal therapy. (Source: Lasers in Medical Science)
Source: Lasers in Medical Science - February 1, 2021 Category: Laser Surgery Source Type: research

Two-dimensional correlation (2D) method for improving the accuracy of OCT-based noninvasive blood glucose concentration (BGC) monitoring
AbstractThe optical scattering coefficient (μs) in the dermis layer of human skin obtained with optical coherence tomography (OCT) has shown to have a strong correlation with the blood glucose concentration (BGC), which can be used for noninvasive BGC monitoring. Unfortunately, the nonhomogeneity in the skin may cause inaccuracies for the BGC analysis. In this paper, we propose a 2D correlation analysis method to identify 2D regions in the skin withμs sensitive to BGC variations and only use data in these regions to calculateμs for minimizing the inaccuracy induced by nonhomogeneity and therefore improving the acc...
Source: Lasers in Medical Science - February 1, 2021 Category: Laser Surgery Source Type: research

Optical changes of human dentin after non-vital bleaching and effect of Er,Cr:YSGG laser on micro-shear bond strength of a self-etch and an etch-and-rinse adhesive system
AbstractThe aim was to evaluate the optical changes of bleached human dentin and the efficacy of Er,Cr:YSGG laser on micro-shear bond strength ( μSBS) of two adhesive systems for immediate and delayed applications. Seventy-two human dentin specimens (1 mm) were obtained. Colour measurements of 30 specimens (control and bleaching groups) were made at baseline, after bleaching and a 7-day delay. Differences at colour (ΔE00), translucency ( ΔTP00) and whiteness ( ΔWID) were calculated by recorded data. Forty-two specimens were used to compare μSBS of a self-etch (Clearfil SE Bond [SE]) and an etch...
Source: Lasers in Medical Science - January 5, 2021 Category: Laser Surgery Source Type: research

Management of peri-implantitis using a diode laser (810  nm) vs conventional treatment: a systematic review
AbstractThe purpose of this study was to systematically assess clinical studies on the effect of using a diode laser in the treatment of peri-implantitis. Study question was “In patients with peri-implantitis around functional dental implants, can treatment by a diode Laser (810 nm) versus conventional treatment be effective in reducing the probing depth?”. The study included only randomized controlled clinical trials that involved patients with peri-implantitis. I ncluded articles evaluated a diode laser (810 nm) used as monotherapy or as adjuvant therapy in the non-surgical treatment while their con...
Source: Lasers in Medical Science - January 5, 2021 Category: Laser Surgery Source Type: research

A meta-analysis of fractional CO 2 laser combined with PRP in the treatment of acne scar
This study aimed to analyze the effectiveness and safety of ablative fractional carbon dioxide laser systems (CO2 AFL) combined with autologous platelet-rich plasma (PRP) in the treatment of acne scars through the retrieval and collection of related literature to further guide the treatment of acne scars. We searched Web of Science, PubMed, Embase, Wanfang Data, Chinese National Knowledge Infrastructure, and VIP Database. All randomized and nonrandomized controlled trials on CO2 AFL combined with PRP in the treatment of acne scars were included, and Revman5.3 systematic review software was used in the meta-analysis. Nine s...
Source: Lasers in Medical Science - January 5, 2021 Category: Laser Surgery Source Type: research

Efficacy of high-intensity laser therapy in patients with adhesive capsulitis: a sham-controlled randomized controlled trial
AbstractAdhesive capsulitis is an idiopathic condition characterized by painful shoulder stiffness, impairs quality of life, and causes disability. The purpose of the study is to evaluate the effects of high-intensity laser therapy (HILT) on pain, disability, and quality of life in patients with adhesive capsulitis. The study was designed as a prospective, double-blinded, and sham-controlled randomized trial. Thirty-six patients diagnosed with adhesive capsulitis were randomized into HILT plus therapeutic exercises, sham-laser plus therapeutic exercises, and control-therapeutic exercises only groups. All groups received 25...
Source: Lasers in Medical Science - January 5, 2021 Category: Laser Surgery Source Type: research

Shear bond strength of a self-adhesive resin cement to dentin surface treated with Nd:YAG and femtosecond lasers
This study aims to evaluate the effect of Nd:YAG and femtosecond lasers irradiation on the shear bond strength (SBS) of a self-adhesive resin cement to the human dentin surface. One hundred extracted third molar teeth were randomly divided into 10 experimental groups according to dentin surface treatments; with and without the bonding agent, Nd:YAG 302  J/cm2 and 440  J/cm2, femtosecond 4  J/cm2 and 7  J/cm2, and control groups were prepared. After surface treatments, a self-adhesive resin cement was luted by using a bonding jig (Ultradent Products Inc.). The specimens were then subjected to shear test ...
Source: Lasers in Medical Science - January 5, 2021 Category: Laser Surgery Source Type: research

Intra-volume processing of gelatine hydrogel by femtosecond laser-induced cavitation
In conclusion, the formation of fully formed channels was made possible with a near-infrared, femtosecond laser beam strongly focused inside gelatine hydrogel blocks through laser-induced cavitation at high dose and low repetition rates. (Source: Lasers in Medical Science)
Source: Lasers in Medical Science - January 5, 2021 Category: Laser Surgery Source Type: research

The efficacy of fractional carbon dioxide laser combined with narrow-band ultraviolet B phototherapy for non-segmental vitiligo: a systematic review and meta-analysis
AbstractFractional carbon dioxide (CO2) laser has been used with conventional treatments for vitiligo, demonstrating more effectiveness compared with conventional treatments alone. Especially, fractional CO2 laser combined with narrow-band ultraviolet B (NB-UVB) was shown to induce more improvement compared with NB-UVB monotherapy for treating stable non-segmental vitiligo. However, the effectiveness of fractional CO2 laser plus NB-UVB for the treatment of non-segmental vitiligo remains controversial. Therefore, this study aimed to confirm the safety and efficacy of fractional CO2 laser combined with NB-UVB compared with N...
Source: Lasers in Medical Science - January 5, 2021 Category: Laser Surgery Source Type: research

Long-pulsed 755-nm alexandrite laser equipped with a sapphire handpiece: unwanted hair removal in darker phototypes
(Source: Lasers in Medical Science)
Source: Lasers in Medical Science - January 5, 2021 Category: Laser Surgery Source Type: research

Fractional CO 2 laser-assisted Botulinum toxin type A delivery for the treatment of primary palmar hyperhidrosis
AbstractIntradermal injections of botulinum toxin type A (BTX-A) have been used successfully to treat patients with primary palmoplantar hyperhidrosis (PPH). However, problems with local injections of BTX-A for palmar hyperhidrosis include injection pain and reduced palmar muscle strength. This case series describes three patients with PPH. Patients were followed up for 3  months and assessed using the minor iodine starch test and the visual analog scale (VAS). Over two sessions within a 2-week interval, all patients received treatment on one palm, while the other palm served as the untreated control. Treated palms re...
Source: Lasers in Medical Science - January 5, 2021 Category: Laser Surgery Source Type: research

Effects of intravenous and transdermal photobiomodulation on the postoperative complications of coronary artery bypass grafting surgery: a randomized, controlled clinical trial
AbstractAlthough coronary artery bypass graft (CABG) surgery is one of the most worldwide commonly performed cardiac surgeries to enhance myocardial perfusion in high-grade myocardial occlusion, it remains a high-risk procedure. Photobiomodulation (PBM) is one of the methods which have been shown to have positive effects on the healing process after CABG and postoperative complications. The aim of this study was to evaluate the efficacy of PBM in patients who underwent a coronary artery bypass graft (CABG). Ths study was conducted with 192 volunteers who electively submitted to CABG. The volunteers were randomly allocated ...
Source: Lasers in Medical Science - January 4, 2021 Category: Laser Surgery Source Type: research

Laser and light-based therapies in the management of rosacea: an updated systematic review
This article reviews and discusses the current use of lasers and light-based therapies in rosacea with reference to all the available literature.This systematic review demonstrates the quality of evidence to support any recommendation on LLBT in rosacea is low-to-moderate. Among all the available devices, PDL holds the most robust evidence. Treatments options should be tailored for each specific clinical scenario as it is unlike that single modality results in complete resolution. Platforms that include two or more devices and combined therapies with topical agents are suitable and they warrant further investigations. (Sou...
Source: Lasers in Medical Science - January 3, 2021 Category: Laser Surgery Source Type: research

Study on the mechanism of photodynamic therapy mediated by 5-aminoketovalerate in human ovarian cancer cell line
AbstractWe aimed to investigate the mechanism and effect of photodynamic treatment mediated by 5-aminoketovalerate (5-ALA-PDT) on human ovarian cancer cells (OVCAR3 cells) and to provide a theoretical basis for the subsequent experimental step in vivo. Human ovarian cancer OVCAR3 cells were randomly divided into four groups: control group, laser irradiation alone group, photosensitizer alone group, and photodynamic treatment group. Alterations in cell morphology were observed with an inverted light microscope; cell viability was examined by CCK-8 assays. The ROS content and apoptosis rate were examined by flow cytometry an...
Source: Lasers in Medical Science - January 3, 2021 Category: Laser Surgery Source Type: research

Transoral laser microsurgery: feasibility of a new exoscopic HD-3D system coupled with free beam or fiber laser
AbstractIn the last decades, new technological devices and instruments have been developed to overcome the technical limits of transoral laser microsurgery. The recent introduction of 3D endoscopy seems to be a promising tool in the field of diagnostic and operative laryngology as an alternative to the traditional microlaryngoscopy. Our work aims to present a novel transoral microsurgical setting that expands the use of exoscopic systems (in this case the VITOM ® 3D-HD) as an alternative to the standard operating microscope. A customized support arm and an adaptor to firmly connect the VITOM® 3D-HD camera to the la...
Source: Lasers in Medical Science - January 3, 2021 Category: Laser Surgery Source Type: research

Association of photobiomodulation therapy (PBMT) and exercises programs in pain and functional capacity of patients with knee osteoarthritis (KOA): a systematic review of randomized trials
AbstractKnee osteoarthritis (KOA) is a common degenerative disease in which several treatments and treatment associations have been investigated. This review analyzed the efficacy of the association of photobiomodulation therapy (PBMT) and exercises for people with KOA in randomized controlled clinical trials. PubMed, Scopus, and EMBASE databases were searched using the following terms: “knee osteoarthritis,” “laser,” “low-level laser,” “photobiomodulation,” “phototherapy,” and “exercise.” Seven RCT studies involving humans that examined PBMT treatment...
Source: Lasers in Medical Science - January 3, 2021 Category: Laser Surgery Source Type: research

Diode laser versus bipolar diathermy for turbinate reduction in cases of inferior turbinate hypertrophy
This study was designed to assess the surgical outcomes of two commonly used techniques for turbinate reduction (diode laser and bipolar diathermy) in selected group of patients with chronic nasal obstruction which resulted from inferior turbinate hypertrophy. The current study was conducted on adult patients with a diagnosis of inferior turbinate hypertrophy. 42 patients (21 in each group) with an age range of 21 –38 years (mean = 26.0 ± 4.1) were included in this work and were randomly distributed in 2 groups: one group was scheduled for diode laser turbinectomy (DLT) while t...
Source: Lasers in Medical Science - January 3, 2021 Category: Laser Surgery Source Type: research

Fractionated carbon dioxide (CO 2 ) laser treatment contributes to trans-nail penetration of rhodamine B and changes of cytokine microenvironment
This study is to determine the role of the fractional CO2 laser in topical drug delivery and the impact of local immune responses. Experimental rabbit nails were treated with fractionated CO2 laser at varied fluencies of 20  mJ, 25 mJ, and 30 mJ and half of which were coated with rhodamine B (RhB). Histological examination was performed by hematoxylin and eosin staining; the penetration of RhB was assessed by the use of confocal laser scanning microscopy; and the expressions of IFN-γ and IL-4 mRNA in situ were dete cted by means of qPCR at 12 h, 24 h, 3 days, and 7 days post-laser i...
Source: Lasers in Medical Science - January 3, 2021 Category: Laser Surgery Source Type: research

Effect of 940  nm laser diode irradiation prior to bonding procedure on postoperative sensitivity following class II composite restorations: a split-mouth randomized clinical trial
AbstractThe aim of this study was to evaluate the effect of 940  nm laser diode on class II composite cavities prior to bonding and restoration process on the postoperative sensitivity (POS). Thirty patients with two bilateral premolars with mesio or disto-occlusal carious lesions were evaluated. In each patient, the teeth were randomly divided into the control and laser groups. After cavity preparation and isolation and before the bonding process, the laser group was subjected to 940 nm irradiation (Epic 10, Biolase, USA) by 400 μ tip continuously at 100 mW with 398 J/cm2 energy density of tip,...
Source: Lasers in Medical Science - January 3, 2021 Category: Laser Surgery Source Type: research

Nomenclature in thulium laser treatment of benign prostatic hyperplasia: it ’s time to pull the rabbit out of the hat
AbstractWe performed a narrative review with the focus on laser settings and surgical procedure with thulium laser. Our primary goal was to define the most valid settings of each surgical procedure to overcome the inconsistency about nomenclature of thulium surgery and to ensure comparability of future publications. A literature search of articles on thulium laser treatment of benign prostatic hyperplasia (BPH) was conducted between 2009 and 2019. We proposed a new classification standard for laser settings and associated surgical procedure. Each article was analyzed and categorized as concordant or discordant referring to...
Source: Lasers in Medical Science - January 3, 2021 Category: Laser Surgery Source Type: research

The beneficial effects of fractional CO 2 laser treatment on perineal changes during puerperium and breastfeeding period: a multicentric study
AbstractChildbirth is a great change in woman life because of hormonal, physical and psychological alterations that are associated with this process. Dyspareunia and perineal pain are commonly reported symptoms in the postpartum period, mainly due to perineal trauma, lacerations, episiotomy, and forceps or vacuum use at delivery. Among non-pharmacological treatment, a new trend is gaining popularity, which is the energy-based therapy, including fractional micro-ablative CO2 laser. We conducted a multicentric retrospective study to assess the efficacy and the possible side effects of CO2 laser treatment on transient vulvova...
Source: Lasers in Medical Science - January 3, 2021 Category: Laser Surgery Source Type: research

Use of fractionated microneedle radiofrequency for necrobiosis lipoidica
(Source: Lasers in Medical Science)
Source: Lasers in Medical Science - January 3, 2021 Category: Laser Surgery Source Type: research

Photobiomodulation and diffusing optical fiber on spinal cord ’s impact on nerve cells from normal spinal cord tissue in piglets
AbstractExperts have proven that photobiological regulation therapy for spinal cord injury promotes the spinal repair following injury. The traditional irradiation therapy mode is indirect (percutaneous irradiation), which could significantly lower the effective use of light energy. In earlier studies, we developed an implantable optical fiber that one can embed above the spinal cord lamina, and the light directly is cast onto the surface of the spinal cord in a way that can dramatically improve energy use. Nonetheless, it remains to be seen whether near-infrared light diffused by embedded optical fiber can have side effec...
Source: Lasers in Medical Science - January 2, 2021 Category: Laser Surgery Source Type: research

Effect of adjunctive diode laser in the non-surgical periodontal treatment in patients with diabetes mellitus: a systematic review and meta-analysis
This study aimed to systematically review and analyze the present randomized clinical trials (RCTs) regarding the clinical efficacy of a diode laser (DL) adjuvant to scaling and root planning (SRP) in patients with chronic periodontitis (CP) who have diabetes mellitus (DM). Five databases (MEDLINE, EMBASE, Cochrane Central Register of Controlled Trails, Web of Science, and Chinese BioMedical Literature Databases) were searched. A meta-analysis was implemented to evaluate periodontal parameters including probing depth (PD) and clinical attachment level (CAL) as primary outcomes. Hemoglobin A1c (HbA1c), plaque index (PI), an...
Source: Lasers in Medical Science - January 2, 2021 Category: Laser Surgery Source Type: research

Effect of low power lasers on prokaryotic and eukaryotic cells under different stress condition: a review of the literature
AbstractRadiations emitted by low power radiation sources have been applied for therapeutic proposals due to their capacity of inactivating bacteria and cancer cells in photodynamic therapy and stimulating tissue cells in photobiomodulation. Exposure to these radiations could increase cell proliferation in bacterial cultures under stressful conditions. Cells in infected or not infected tissue injuries are also under stressful conditions and photobiomodulation-induced regenerative effect on tissue injuries could be related to effects on stressed cells. The understanding of the effects on cells under stressful conditions cou...
Source: Lasers in Medical Science - January 2, 2021 Category: Laser Surgery Source Type: research

Clinical efficacy comparison of low-temperature plasma radiofrequency ablation and Nd:YAG laser in treating recurrent acquired nasolacrimal duct obstruction
AbstractTo evaluate the effectiveness and safety of low-temperature plasma radiofrequency ablation (coblation) and Nd:YAG laser in treating recurrent nasolacrimal duct obstruction. A prospective study was performed on patients who agreed to be treated with coblation or Nd:YAG laser for recurrent nasolacrimal duct obstruction after failed lacrimal Nd:YAG laser combined with silicone intubation. The visual analogue scale (VAS) pain grade was assessed at baseline, immediately, and 3 and 7  days after surgery. The degree of watering, lacrimal passage irrigation, and complications were also evaluated 1 week and 1, 3, ...
Source: Lasers in Medical Science - November 5, 2020 Category: Laser Surgery Source Type: research

Dose-dependent effect of the pulsed Nd:YAG laser in the treatment of crushed sciatic nerve in Wister rats: an experimental model
The objective of the study was to investigate the efficacy of three energy densities 4, 10, and 50  J/cm2 of pulsed Nd:YAG laser for the treatment of crushed sciatic nerve in Wister rats by evaluating changes in the sciatic functional index and the electrophysiology.A total of 180 Wistar rats were involved in the study. Rats were randomly assigned to five groups. Rats were subjected to the sciatic nerve crushing. Control negative (CONT-ve), which received no crushing; control positive (CONT+ve), which received crushing with no laser; and HILT-4, HILT-10, and HILT-50 groups, which received pulsed Nd:YAG laser (10  ...
Source: Lasers in Medical Science - November 5, 2020 Category: Laser Surgery Source Type: research

Angiogenic protein synthesis after photobiomodulation therapy on SHED: a preliminary study
This study evaluated the viability, proliferation, and protein expression after photobiomodulation (PBM) of stem cell from human exfoliated deciduous teeth (SHED). The groups were the following: G1 (2.5  J/cm2), G2 (3.7 J/cm2), and control (not irradiated). According to the groups, cells were irradiated with InGaAlP diode laser at 660 nm wavelength, continuous mode, and single time application. After 6 h, 12 h, and 24 h from irradiation, the cell viability and proliferation, and the protein e xpression were analyzed by MTT, crystal violet, and ELISA multiplex assay, respectively. Twenty-four h...
Source: Lasers in Medical Science - November 5, 2020 Category: Laser Surgery Source Type: research

ILIB (intravascular laser irradiation of blood) as an adjuvant therapy in the treatment of patients with chronic systemic diseases —an integrative literature review
AbstractTo perform an integrative review of the literature on the effectiveness of intravascular laser irradiation of blood (ILIB) as an adjunct therapy in the treatment of chronic systemic diseases. This is an integrative literature review that included non-randomized and randomized controlled clinical trials that specifically evaluated the therapeutic effect of ILIB on chronic systemic diseases, without restriction of time, and written in English. The Medical Publications (PubMed)/MEDLINE database was used. MeSH (Medical Subject Headings) was used to select search descriptors with the Boolean operators “AND/OR.&rdq...
Source: Lasers in Medical Science - November 5, 2020 Category: Laser Surgery Source Type: research

Efficacy, safety, and guidelines of application of the fractional ablative laser erbium YAG 2940 nm and non-ablative laser erbium glass in rejuvenation, skin spots, and acne in different skin phototypes: a systematic review
AbstractNon-ablative and ablative fractional erbium lasers are among the most frequently used resources in dermatology for facial rejuvenation and for treating dermatological disorders. This type of erbium laser can be found at wavelengths of 1540 or 1550 nm, which are classified as non-ablative erbium glass, and at 2940 nm, classified as ablative erbium YAG. Despite the reports of their clinical benefits, few scientific studies have demonstrated the efficacy and safety of these lasers in the short or long term. In order to substantiate the effects, benefits, and safety of applying the erbium glass and erbium YAG lasers, a...
Source: Lasers in Medical Science - November 5, 2020 Category: Laser Surgery Source Type: research

Resumption of laser/IPL skin services post COVID-19 lockdown —British Medical Laser Association (BMLA) guidance document
AbstractThe COVID-19 pandemic has had a significant negative impact on the global health economies. As health care resources have been prioritised to cater for patients affected by COVID-19, routine health care services have remained suspended. In an effort to slow the spread of SARS-CoV-2 virus, the UK introduced a country-wide lockdown which came into effect on the 23rd March 2020. Since then, clinics offering laser and intense pulsed light services have remained closed for business. As the rate of COVID-19 infection slows, the UK government has issued guidance for lifting of the lockdown in a cautious and phased manner....
Source: Lasers in Medical Science - November 5, 2020 Category: Laser Surgery Source Type: research

Photobiomodulation with 630-nm LED radiation inhibits the proliferation of human synoviocyte MH7A cells possibly via TRPV4/PI3K/AKT/mTOR signaling pathway
AbstractPhototherapy has been used to treat postoperative pain and inflammatory response in rheumatoid arthritis. Confidence in this approach, however, is impaired by lack of understanding of the light-triggered cellular and molecular mechanisms. The purpose of this study was to characterize the response of human synoviocyte MH7A cells to visible LED red light in an attempt to elucidate the associated action mechanism. Human synoviocyte MH7A cells were treated with 630-nm LED light after stimulation of tumor necrosis factor- α (TNF-α). The effects of light radiation on cell proliferation and migration were dete...
Source: Lasers in Medical Science - November 5, 2020 Category: Laser Surgery Source Type: research

Examination of the effect of combined use of Er:YAG laser irradiation and mechanical force loading on bone metabolism using primary human gingival fibroblasts
AbstractProlonged treatment and painful tooth movement are major problems for patients undergoing orthodontic treatment. Accelerating the movement of teeth leads to shortening of the treatment period, so various studies on the movement of teeth have been conducted in the field of orthodontics. In previous studies, we performed a fiber incision-like fiberotomy using an Er:YAG laser in rats and confirmed acceleration of tooth movement. Therefore, in this study, the effect of Er:YAG laser irradiation on human gingival fibroblasts was investigated in vitro. Human gingival fibroblasts (2.0  × 105 cells) were...
Source: Lasers in Medical Science - November 5, 2020 Category: Laser Surgery Source Type: research