An Anatomical Approach to Determine the Location of the Sinoatrial Node During Catheter Ablation
This study evaluated the usefulness of the anatomically defined SAN by comparing it with the electrically confirmed SAN (e ‐SAN) to predict the top‐most position of e‐SAN and thus establish a safe and more efficient anatomical reference for SVC isolation than the previously reported reference of the right superior pulmonary vein (RSPV) roof.Methods and ResultsThe e ‐SAN was identified as the earliest activation site in the electro‐anatomical map obtained during sinus rhythm. The anatomically defined SAN, the cranial edge of the crista terminalis (CT) visualized with intracardiac echocardiography (CT top), and the...
Source: Journal of Cardiovascular Electrophysiology - February 18, 2021 Category: Cardiology Authors: Keiko Shimamoto, Kenichiro Yamagata, Kenzaburo Nakajima, Tsukasa Kamakura, Mitsuru Wada, Yuko Inoue, Koji Miyamoto, Takashi Noda, Satoshi Nagase, Kengo F. Kusano Tags: ORIGINAL ARTICLES Source Type: research

Effect of Obesity and Epicardial Fat/Fatty Infiltration on Electrical and Structural Remodeling Associated With Atrial Fibrillation in a Novel Canine Model of Obesity and Atrial Fibrillation: A Comparative Study
AbstractBACKGROUNDHow obesity and epicardial fat influence atrial fibrillation (AF) is unknown.METHODSTo investigate the effect of obesity/epicardial fat on the AF substrate, we divided 20 beagle dogs of normal weight into 4 groups (n=5 each): One of the 4 groups (Obese ‐rapid atrial pacing [RAP] group) served as a novel canine model of obesity and AF. The other 3 groups comprised dogs fed a standard diet without RAP (Control group), dogs fed a high‐fat diet without RAP (Obese group), or dogs fed a standard diet with RAP (RAP group). All underwent electrophysio logy study, and hearts were excised for histopathologic an...
Source: Journal of Cardiovascular Electrophysiology - February 18, 2021 Category: Cardiology Authors: Naoto Otsuka, Yasuo Okumura, Masaru Arai, Sayaka Kurokawa, Koichi Nagashima, Ryuta Watanabe, Yuji Wakamatsu, Seina Yagyu, Kimie Ohkubo, Toshiko Nakai, Hiroyuki Hao, Rie Takahashi, Yoshiki Taniguchi, Yxin Li Tags: ORIGINAL ARTICLES Source Type: research

Recurrent Unsustained Long RP Tachycardia: What is the Mechanism?
This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 18, 2021 Category: Cardiology Authors: Hussam Ali, Guido De Ambroggi, Pierpaolo Lupo, Sara Foresti, Carmine De Lucia, Dario Turturiello, Edoardo Paganini, Riccardo Cappato Tags: EP ROUNDS Source Type: research

Reflections from the Book of the Dead: Weighing the Impact of Epicardial Fat on Atrial Fibrillation Vulnerability
This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 18, 2021 Category: Cardiology Authors: T. Jared Bunch Tags: EDITORIAL ‐ INVITED Source Type: research

Effect of Metformin on Outcomes of Catheter Ablation for Atrial Fibrillation
ConclusionsIn patients with DM, treatment with metformin appears to be independently associated with a significant reduction in the risk of recurrent atrial arrhythmias after CA for AF. Whether this effect is due to glycemic control or pleiotropic effects on electroanatomical mechanisms of AF remains to be determined.This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 18, 2021 Category: Cardiology Authors: Amrish Deshmukh, Michael Ghannam, Jackson Liang, Mohammed Saeed, Ryan Cunnane, Hamid Ghanbari, Rakesh Latchamsetty, Thomas Crawford, Syeda Atiqa Batul, Eugene Chung, Frank Bogun, Krit Jongnarangsin, Frank Pelosi, Aman Chugh, Fred Morady, El Tags: ORIGINAL ARTICLES Source Type: research

Efficacy of LGE ‐MRI‐Guided Fibrosis Ablation vs. Conventional Catheter Ablation of Atrial Fibrillation: The DECAAF II Trial: Study Design
ConclusionThe DECAAF II trial is the first prospective, randomized, multicenter trial of patients with persistent AF using imaging defined atrial fibrosis as a treatment target. The trial will help define an optimal approach to catheter ablation of persistent AF, further our understanding of influencers of ablation lesion formation, and refine selection criteria for ablation based on atrial myopathy burden.This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 18, 2021 Category: Cardiology Authors: Nassir F. Marrouche, Tom Greene, J Michael Dean, Eugene G. Kholmovski, Leonie Morrison ‐de Boer, Moussa Mansour, Hugh Calkins, Francis Marchlinski, David Wilber, Gerhard Hindricks, Christian Mahnkopf, Pierre Jais, Prashanthan Sanders, Johan Tags: ORIGINAL ‐ ELECTROPHYSIOLOGY Source Type: research

First experience of POLARx ™ versus Arctic Front Advance™: An early technology comparison
ConclusionThe POLARx cryoballoon is effective for pulmonary vein isolation. Measured isolation and nadir temperatures are lower compared to the predicate Arctic Front Advance catheter. The technology appears similar in acute efficacy and has a short learning curve, but formal dosing studies may be required to prove equivalence of efficacy.This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 16, 2021 Category: Cardiology Authors: Antonio Creta, Viijayabharathy Kanthasamy, Richard J. Schilling, James Rosengarten, Fakhar Khan, Shohreh Honarbakhsh, Mark J. Earley, Ross J. Hunter, Malcom Finlay Tags: ORIGINAL ARTICLES Source Type: research

Periodontitis and the Outcome of Atrial Fibrillation Ablation: Porphyromonas Gingivalis Is Related to Atrial Fibrillation Recurrence
ConclusionPeriodontitis was related to late recurrence of AF after RFCA.P. gingivalis type IV may be pathogenic for AF recurrence after RFCA.This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 16, 2021 Category: Cardiology Authors: Shunsuke Miyauchi, Takehito Tokuyama, Tomoaki Shintani, Hiromi Nishi, Yuta Hamamoto, Kazuhisa Ouhara, Hisako Furusho, Mutsumi Miyauchi, Hitoshi Komastuzawa, Yukiko Nakano Tags: ORIGINAL ARTICLES Source Type: research

A Second Cryoballoon System ‐ new and improved?
This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 16, 2021 Category: Cardiology Authors: Wilber W. Su Tags: EDITORIAL ‐ INVITED Source Type: research

Premature battery depletion of EMBLEM subcutaneous implantable cardioverter ‐defibrillators
AbstractThe EMBLEM subcutaneous implantable cardioverter defibrillator (S ‐ICD) has an expected longevity of 7 years. In August 2019, Boston Scientific released an advisory regarding a limited subset of ~400 S‐ICDs that exhibited an increased likelihood of an electrical component malfunction causing accelerated battery depletion. We observed several cases of nonadviso ry S‐ICD early battery depletion and sought to systematically evaluate the cohort of EMBLEM devices implanted and followed in our medical center. Out of 118 nonadvisory EMBLEM S‐ICDs with a median time to most recent follow‐up after implant of 735 d...
Source: Journal of Cardiovascular Electrophysiology - February 15, 2021 Category: Cardiology Authors: James E. Ip Tags: BRIEF COMMUNICATION Source Type: research

Brugada phenocopy in a patient with unstable angina and three ‐vessel coronary artery disease
This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 15, 2021 Category: Cardiology Authors: Gavino Casu, Paola Berne, Graziana Viola, Stefano Bandino, Adrian Baranchuk Tags: CASE REPORT Source Type: research

Unusual Cause for Loss of Left Ventricular Capture in Patient with Cardiac Resynchronization due to Tuberculous Pericarditis
This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 15, 2021 Category: Cardiology Authors: Yiu ‐Hei Tse, Hung‐Fat Tse Tags: CASE REPORT Source Type: research

Issue Information
(Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 11, 2021 Category: Cardiology Tags: ISSUE INFORMATION Source Type: research

Long ‐Term Clinical Outcomes of Cardiac Sympathetic Denervation in Patients with Refractory Ventricular Arrhythmias
In this study, we sought to retrospectively analyse the long‐term outcomes of CSD in patients with refractory VT and/or VT storm with a majority of the patients being taken up for CSD ahead of catheter ablation.MethodWe included consecutive patients with SHD who underwentCSD from 2010 to 2019 owing to refractory VT. A complete response to CSD was defined as a greater than 75% reduction in the frequency of ICD shocks for VT.ResultsA total of 65 patients (50 male, 15 female) were included. The underlying VT substrate was ischemic heart disease (IHD) in 30 (46.2%) patients while the remaining 35 (53.8%) patients had other n...
Source: Journal of Cardiovascular Electrophysiology - February 11, 2021 Category: Cardiology Authors: Parag Barwad, Kunal Sinkar, Neeta Bachani, Rushil Shah, Vihang Shah, Binay Kumar, Shrikant Bhoskar, Neeraj Desai, Yash Lokhandwala Tags: ORIGINAL ARTICLES Source Type: research

The Saga of Tendril Leads Continues: Should We Continue to Bury our Heads in the Sand?
This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 11, 2021 Category: Cardiology Authors: Mikhael F. El ‐Chami Tags: EDITORIAL ‐ INVITED Source Type: research

Novel Mapping Techniques for Rotor Core Detection using Simulated Intracardiac Electrograms
ConclusionThe core of rotors can be successfully identified from EGMs using novel techniques; thus, providing motivation for future clinical implementations.This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 11, 2021 Category: Cardiology Authors: Vasanth Ravikumar, Elizabeth Annoni, Preethy Parthiban, Sharon Zlochiver, Henri Roukoz, Siva Mulpuru, Elena G. Tolkacheva Tags: ORIGINAL ARTICLES Source Type: research

Sympathectomy ‐ A “one hit wonder” for life?
This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 11, 2021 Category: Cardiology Authors: Fabrizio R. Assis, Harikrishna Tandri Tags: EDITORIAL ‐ INVITED Source Type: research

Identification of deliberate catheter motion at the left atrial posterior wall during pulmonary vein isolation: Validity of respiratory motion adjustment
AbstractBackgroundDuring automated radiofrequency (RF) annotation ‐guided pulmonary vein isolation (PVI), respiratory motion adjustment (RMA) is recommended, yet lacksin vivo validation.MethodsFollowing contact force (CF) PVI (continuous RF, 30W) using general anaesthesia and automated RF annotation ‐guidance (VISITAG™: force‐over‐time 100% minimum 1g; 2mm position stability; ACCURESP™ RMA “off”) in 25 patients, we retrospectively examined RMA settings “on” versus “off” at the left atrial posterior wall (LAPW).ResultsRespiratory motion detection occurred in 8, permitt...
Source: Journal of Cardiovascular Electrophysiology - February 11, 2021 Category: Cardiology Authors: David R. Tomlinson, Katie Biscombe, John True, Joanne Hosking, Adam J. Streeter Tags: ORIGINAL ‐ ELECTROPHYSIOLOGY Source Type: research

Elective replacement of a 4 ‐year‐old leadless pacemaker: new approach for end‐of‐life management
This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 11, 2021 Category: Cardiology Authors: Paolo De Filippo, Giovanni Malanchini, Cristina Leidi, Marco Racheli, Gabriele Ferrari, Michele Senni, Paola Ferrari Tags: CASE REPORT Source Type: research

Intracardiac echocardiography ‐guided implantation of the Watchman FLX left atrial appendage closure device
ConclusionThe Watchman FLX device can be safely implanted with intraprocedural ICE imaging instead of TEE. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 10, 2021 Category: Cardiology Authors: Mohit K. Turagam, Petr Neuzil, Jan Petru, Pavel Hala, Tomas Mraz, Jiri Baroch, Veronika Lekesova, Milena Prokopova, Srinivas R. Dukkipati, Vivek Y. Reddy Tags: ORIGINAL ARTICLES Source Type: research

Long ‐term outcomes of index cryoballoon ablation or point‐by‐point radiofrequency ablation in patients with atrial fibrillation and systolic heart failure
AbstractCatheter ablation is an established  effective approach for the treatment of atrial fibrillation (AF) in patients with heart failure, however, the role of cryoablation in this setting is unclear. Procedural success and left ventricular systolic dysfunction (LVEF) improvement in patients with LVEF ≤ 45% undergoing index catheter ablation with cryoablation were evaluated. Freedom from AF recurrence was seen in 43% rising to 59% following repeat procedure. There were significant improvements in LVEF and functional status at long‐term follow‐up. Results were comparable to a contemporaneous coh...
Source: Journal of Cardiovascular Electrophysiology - February 10, 2021 Category: Cardiology Authors: S. Prabhu, N. Ahluwalia, S. M. Tyebally, A. S. C. Dennis, S. O. Malomo, A. T. Abiodun, A. Tyrlis, G. Dhillon, L. Segan, A. Graham, S. Honarbakhsh, V. Sawhney, S. Sporton, M. Lowe, M. Finlay, M. J. Earley, P. Lambiase, R. J. Schilling, R. Tags: ORIGINAL ARTICLES Source Type: research

Efficacy of Medical and Ablation Therapy for Inappropriate Sinus Tachycardia: a Single Center Experience
AbstractBackgroundEffective therapy for inappropriate sinus tachycardia (IST) remains challenging with high rates of treatment failure and symptom recurrence. It is uncertain how effective pharmacotherapy and procedural therapy are long ‐term, with poor response to medical therapy in general.MethodsWe retrospectively reviewed all patients with the diagnosis of IST at a tertiary academic medical center from 1998 to 2018. We extracted data related to prescribing patterns and symptom response to medical therapy and sinus node modification (SNM), assessing efficacy and peri ‐procedural complication rates.ResultsA total of ...
Source: Journal of Cardiovascular Electrophysiology - February 10, 2021 Category: Cardiology Authors: Samuel A. Shabtaie, Chance M. Witt, Samuel J. Asirvatham Tags: ORIGINAL ARTICLES Source Type: research

Increased Incidence of Electrical Abnormalities in a Pacemaker Lead Family
AbstractINTRODUCTIONSeveral recent studies have raised concern about noise detections on Tendril pacemaker leads, which may represent insulation failure or algorithm ‐driven over‐reporting of physiologic signals.METHODSWe identified all pacemaker leads actively followed at Albany Medical Center, of which 1111 leads (262 Abbott Tendril, 576 Medtronic CapSure, 30 Fineline, 195 Ingevity, 48 Dextrus) in 703 patients were included in this observational study. Electrical abnormalities, comprising low impedance measurements
Source: Journal of Cardiovascular Electrophysiology - February 10, 2021 Category: Cardiology Authors: Evan Adelstein, Lane Zhang, Haider Nazeer, Alfred Loka, David Steckman Tags: ORIGINAL ‐ DEVICES Source Type: research

Tricuspid Valve Annuloplasty and Mitral Valve Replacement are Associated with Bradyarrhythmia after Mitral Valve Surgery
ConclusionsAfter mitral valve surgery a relevant subgroup of patients requires pacemaker implantation – most for atrioventricular block. We identified mitral valve replacement and tricuspid ring annuloplasty as significant operative risk factors and insulin dependent diabetes mellitus as a demographic risk factor. While anatomic relationships help explain the operative risk factors the role of dia betes mellitus is not completely understood.This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 10, 2021 Category: Cardiology Authors: Florian Ernst Martin Herrmann, Anne ‐Sophie Schleith, Helen Graf, Sebastian Sadoni, Christian Hagl, Erik Bagaev, Gerd Juchem Tags: ORIGINAL ARTICLES Source Type: research

Treatment of Inappropriate Sinus Tachycardia: Still A Long Way To Go
This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 10, 2021 Category: Cardiology Authors: Riccardo Cappato Tags: EDITORIAL ‐ INVITED Source Type: research

One Electrogram ‐Tracing Tells All: what is the mechanism of this supraventricular tachycardia?
This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 10, 2021 Category: Cardiology Authors: Moyuru Hirata, Yuji Wakamatsu, Koichi Nagashima, Sayaka Kurokawa, Naoto Otsuka, Seina Yagyu, Shu Hirata, Toshiko Nakai, Yasuo Okumura Tags: EP ROUNDS Source Type: research

A method to screen left ventricular dysfunction through ECG based on convolutional neural network
ConclusionOur results demonstrate that a well ‐trained CNN algorithm may be used as a low‐cost and non‐invasive method to identify patients with left ventricular dysfunction.This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 10, 2021 Category: Cardiology Authors: Jin ‐Yu Sun, Yue Qiu, Hong‐Cheng Guo, Yang Hua, Bo Shao, Yu‐Cong Qiao, Jin Guo, Han‐Lin Ding, Zhen‐Ye Zhang, Ling‐Feng Miao, Ning Wang, Yu‐Min Zhang, Yan Chen, Juan Lu, Min Dai, Chang‐Ying Zhang, Ru‐Xing Wang Tags: ORIGINAL ARTICLES Source Type: research

Multi ‐lead cephalic venous access and long‐term performance of high‐voltage leads
ConclusionCRT ‐D implantation via the cephalic route is not significantly associated with premature ICD lead failure. Female gender and BMI are predictors of lead failure.This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 10, 2021 Category: Cardiology Authors: Zaki Akhtar, Idris Harding, Ahmed I. Elbatran, Hanney Gonna, Nilanka N. Mannakkara, Lisa WM Leung, Zia Zuberi, Abhay Bajpai, Simon Pearse, Andrew T. Cox, Anthony Li, Fadi Jouhra, Oswaldo Valencia, Zhong Chen, Manav Sohal, Ian Beeton, Mark Tags: ORIGINAL ‐ DEVICES Source Type: research

Premature Battery Depletion of EMBLEM Subcutaneous Implantable Cardioverter ‐Defibrillators (S‐ICD)
This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 10, 2021 Category: Cardiology Authors: James E. Ip Tags: BRIEF COMMUNICATION Source Type: research

An Emblematic Defibrillator Problem
This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 10, 2021 Category: Cardiology Authors: Robert G. Hauser, Jay D. Sengupta Tags: EDITORIAL ‐ INVITED Source Type: research

Protection of the Esophagus During Catheter Ablation of Atrial Fibrillation
This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 9, 2021 Category: Cardiology Authors: Mahmoud Houmsse, Emile G. Daoud Tags: REVIEW Source Type: research

Late ‐gadolinium Enhancement Properties associated with Atrial Fibrillation Rotors in Patients with Persistent Atrial Fibrillation
ConclusionAF rotors are mostly distributed in relatively weak and much more heterogenous LGE areas.This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 9, 2021 Category: Cardiology Authors: Toshihiro Nakamura, Kunihiko Kiuchi, Koji Fukuzawa, Mitsuru Takami, Yoshiaki Watanabe, Yu Izawa, Hideya Suehiro, Tomomi Akita, Makoto Takemoto, Jun Sakai, Atsusuke Yatomi, Yusuke Sonoda, Hiroyuki Takahara, Kazutaka Nakasone, Kyoko Yamamoto, Tags: ORIGINAL ARTICLES Source Type: research

Open ‐Irrigation for Radiofrequency Ablation for Atrial Fibrillation: Worth Its Salt?
This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 9, 2021 Category: Cardiology Authors: Lukasz Cerbin, Wendy S. Tzou Tags: EDITORIAL ‐ INVITED Source Type: research

A novel treatment for esophageal lesions following atrial fibrillation ablation
This study presents a novel technique for the treatment of a deep esophageal ulcer after ablation of paroxysmal atrial fibrillation (AF). Pulmonary vein isolation was performed using a radiofrequency irrigated tip catheter. On Day 5 of follow ‐up, a deep esophageal ulcer was observed. No significant visual improvement was observed after conventional treatment. Endoscopic negative pressure therapy in the esophagus was then applied for 5 days. A significant decrease in diameter and depth of the lesion was observed, possibly preventing perforation. Endoscopic negative pressure therapy can be used to heal thermal lesi...
Source: Journal of Cardiovascular Electrophysiology - February 6, 2021 Category: Cardiology Authors: Esteban W. R. Rivarola, Eduardo Moura, Marco Chou, Luciana Seabra, Carina Hardy, Mauricio Scanavacca Tags: CASE REPORT Source Type: research

Cryoballoon atrial fibrillation ablation: Single ‐center safety and efficacy data using a novel cryoballoon technology compared to a historical balloon platform
AbstractIntroductionCatheter ablation is superior to drugs regarding atrial fibrillation (AF) recurrence, symptoms improvement, and mortality reduction in heart failure. POLARx ™ is a novel cryoballoon, with technical improvements seeking to improve outcomes. So far, its clinical evidence is restricted to a case report.MethodsTo compare the POLARx ™ cryoballoon procedural safety and efficacy to the already established Arctic Front Advance PRO™ (AFAP) in a single‐center cohort study, consecutive patients undergoing AF cryoablation with the POLARx™ were enrolled. Data were prospectively gathered. PO...
Source: Journal of Cardiovascular Electrophysiology - February 4, 2021 Category: Cardiology Authors: Adriano Nunes Kochi, Massimo Moltrasio, Fabrizio Tundo, Stefania Riva, Ciro Ascione, Maria Antonietta Dessanai, Francesca Pizzamiglio, Giulia Vettor, Selene Cellucci, Alessio Gasperetti, Claudio Tondo, Gaetano Fassini Tags: ORIGINAL ‐ ELECTROPHYSIOLOGY Source Type: research

Arctic Front Versus POLARx Cryoballoon: Is There a Winner?
This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 3, 2021 Category: Cardiology Authors: Lohit Garg, Pasquale Santangeli Tags: EDITORIAL ‐ INVITED Source Type: research

Intracardiac Echocardiography ‐Guided Implantation of the Watchman‐FLX Left Atrial Appendage Closure Device
AbstractBackgroundThe next ‐generation Watchman FLX LAAC device has: i) an atraumatic closed distal end, ii) reduced height, iii) a recessed screw hub to decrease device‐related thrombus (DRT), iv) 2 rows of J‐shape anchors so redeployment is possible after full recapture, and v) ability to treat a greater size range of LAA ostia.ObjectiveTo report, for the first time, the feasibility and safety of ICE ‐guided Watchman FLX implantation.MethodsA single ‐center prospective registry of AF patients planned for LAAC with the FLX device underwent ICE‐guided implantation with conscious sedation. TEE imaging was done p...
Source: Journal of Cardiovascular Electrophysiology - February 3, 2021 Category: Cardiology Authors: Mohit K. Turagam, Petr Neuzil, Jan Petru, Pavel Hala, Tomas Mraz, Jiri Baroch, Veronika Lekesova, Milena Prokopova, Srinivas R. Dukkipati, Vivek Y. Reddy Tags: ORIGINAL ARTICLES Source Type: research

Circulating intermediate monocytes and atrial structural remodeling associated with atrial fibrillation recurrence after catheter ablation
ConclusionIntermediate monocytes were significantly positively correlated with SRM. PIM ≥ 10% was associated with a VR ≥ 13.3% on LGE‐MRI, which predicted AF recurrence after catheter ablation.This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 3, 2021 Category: Cardiology Authors: Hideya Suehiro, Kunihiko Kiuchi, Koji Fukuzawa, Naofumi Yoshida, Mitsuru Takami, Yoshiaki Watanabe, Yu Izawa, Tomomi Akita, Makoto Takemoto, Jun Sakai, Toshihiro Nakamura, Atsusuke Yatomi, Hiroyuki Takahara, Yusuke Sonoda, Kazutaka Nakasone, Tags: ORIGINAL ARTICLES Source Type: research

Entering the new ICE age with Watchman FLX
This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 3, 2021 Category: Cardiology Authors: Christopher R. Ellis Tags: EDITORIAL ‐ INVITED Source Type: research

Associations of anemia with stroke, bleeding, and mortality in atrial fibrillation: A systematic review and meta ‐analysis
ConclusionAnemia is a frequently observed comorbidity in patients with AF, and is associated with an increased risk of all ‐cause, cardiovascular and noncardiovascular mortality, stroke/systemic thromboembolism, and major and gastrointestinal bleeding. Future studies are required to explore the causes of anemia in AF, and whether investigation and treatment may be clinically beneficial in affected individuals. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 2, 2021 Category: Cardiology Authors: Samuel J. Tu, Nicole Hanna ‐Rivero, Adrian D. Elliott, Nicholas Clarke, Sonia Huang, Bradley M. Pitman, Celine Gallagher, Dominik Linz, Rajiv Mahajan, Dennis H. Lau, Prashanthan Sanders, Christopher X. Wong Tags: ORIGINAL ‐ ELECTROPHYSIOLOGY Source Type: research

Protocol driven periprocedural anticoagulation for left atrial ablation
AbstractIntroductionA weight ‐based heparin dosing policy adjusted for preprocedural oral anticoagulation was implemented to reduce the likelihood of subtherapeutic dosing during left atrial catheter ablation procedures. We hypothesized that initiation of the protocol would result in a greater prevalence of therapeutic activa ted clotting time (ACT) values and decreased time to therapeutic ACT during left atrial ablation procedures.MethodsA departmental protocol was initiated for which subjects received intravenous unfractionated heparin (UFH) to achieve and maintain a goal of ACT>300  s. Initial bolus dose was...
Source: Journal of Cardiovascular Electrophysiology - February 2, 2021 Category: Cardiology Authors: Christopher J. Bradley, Brian D. Williamson, Julie George, David E. Haines Tags: ORIGINAL ARTICLES Source Type: research

Long ‐term Outcomes of Index Cryo‐balloon ablation or Point by Point Radiofrequency ablation in Patients with Atrial Fibrillation and Systolic Heart Failure
Structured AbstractBackgroundAlthough catheter ablation (CA) is an effective treatment for patients with atrial fibrillation (AF) and left ventricular systolic dysfunction (LVSD), the efficacy of an initial cryo ‐ablation strategy is unknown.MethodsOutcomes of patients undergoing CA with either index cryoablation (CRYO) or radiofrequency ablation (RFA) for AF from January 2008 until March 2018, with pre ‐ablation LVEF≤45% were evaluated.Results206 patients met inclusion criteria (CRYO: n=76, RFA: n=130). Other than being younger, having a lower average CHADS2VASC score and more patients with long ‐standing persist...
Source: Journal of Cardiovascular Electrophysiology - February 2, 2021 Category: Cardiology Authors: S Prabhu, N Ahluwalia, SM Tyebally, Dennis ASC, SO Malomo, AT Abiodun, A Tyrlis, G Dhillon, L Segan, A Graham, S Honarbakhsh, V Sawhney, S Sporton, M Lowe, M Finlay, MJ Earley, P Lambiase, RJ Schilling, RJ Hunter Tags: ORIGINAL ARTICLES Source Type: research

Feasibility of catheter ablation in patients with persistent atrial fibrillation guided by fragmented late ‐gadolinium enhancement areas
ConclusionsFLA ablation could terminate AF or convert it to AT in half of the patients. No AF recurrence was documented in patients with a favorable response.This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 2, 2021 Category: Cardiology Authors: Kunihiko Kiuchi, Koji Fukuzawa, Mitsuru Takami, Yoshiaki Watanabe, Yu Izawa, Mayumi Shigeru, Hiroyuki Oonishi, Hideya Suehiro, Tomomi Akita, Makoto Takemoto, Atsusuke Yatomi, Toshihiro Nakamura, Jun Sakai, Kazutaka Nakasone, Yusuke Sonoda, Tags: ORIGINAL ARTICLES Source Type: research

Revisiting Atrial Pacing in the Long QT Genotype Era
This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 2, 2021 Category: Cardiology Authors: Gregory Webster Tags: EDITORIAL ‐ INVITED Source Type: research

Ultralow temperature cryoablation: Safety and efficacy of preclinical atrial and ventricular lesions
ConclusionsULTC created effective and efficient atrial and ventricular lesions in vivo without procedural complications in two large animal models. ULTC lesions were transmural, contiguous, and durable over 3 months. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 1, 2021 Category: Cardiology Authors: Felix Bourier, Masateru Takigawa, Anna Lam, Konstantinos Vlachos, F. Daniel Ramirez, Claire A. Martin, Antonio Frontera, Takeshi Kitamura, Josselin Duchateau, Thomas Pambrun, Nicolas Derval, Arnaud Denis, Jerry Cox, David Cabrita, Alexander Tags: ORIGINAL ‐ ELECTROPHYSIOLOGY Source Type: research

Catheter ablation of atrial fibrillation using ablation index ‐guided high‐power technique: Frankfurt AI high‐power 15‐month follow‐up
ConclusionThe AI ‐HP (50 W) appears as an efficient ablation technique in treating AF and leads to a high single‐procedure arrhythmia‐free survival at 15 months. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 1, 2021 Category: Cardiology Authors: Shaojie Chen, Boris Schmidt, Stefano Bordignon, Shota Tohoku, Verena C. Urban, Britta Schulte ‐Hahn, K. R. Julian Chun Tags: ORIGINAL ARTICLES Source Type: research

Atrial fibrillation and flutter in patients hospitalized for COVID ‐19: The challenging role of digoxin
(Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 1, 2021 Category: Cardiology Authors: Eftychios Siniorakis, Spyridon Arvanitakis, Antonios Katsianis, Maximilianos Elkouris Tags: LETTER TO THE EDITOR Source Type: research

Outcomes of two versus three incision techniques: Results from the subcutaneous ICD post ‐approval study
AbstractBackgroundTraditionally, implantation of the subcutaneous implantable cardioverter defibrillator (S ‐ICD) requires incisions near the lateral chest wall, the xyphoid, and the superior sternal region (three‐incision technique [3IT]). A two‐incision technique (2IT) avoids the superior incision and has been shown to be a viable alternative in small studies with limited follow‐up.ObjectivesTo report on the long ‐term safety and efficacy of the 2IT compared to the 3IT procedure in a large patient cohort.MethodsPatients enrolled in the S ‐ICD post approval study (PAS) were stratified by procedural technique (...
Source: Journal of Cardiovascular Electrophysiology - February 1, 2021 Category: Cardiology Authors: Mikhael El ‐Chami, Raul Weiss, Martin C. Burke, Michael R. Gold, Jordan M. Prutkin, Gautham Kalahasty, Sharon Shen, Michael J. Mirro, Nathan Carter, Johan D. Aasbo Tags: ORIGINAL ARTICLES Source Type: research

Role for digoxin in patients hospitalized with COVID ‐19 and atrial arrhythmias
(Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - February 1, 2021 Category: Cardiology Authors: Bradley Peltzer, Bruce B. Lerman, Parag Goyal, Jim W. Cheung Tags: RESPONSE TO LETTER TO EDITOR Source Type: research

Patch Monitors for Arrhythmia Monitoring in Patients for Suspected Inherited Arrhythmia Syndrome
CONCLUSIONPatch monitors may simplify the evaluation of patients for an inherited arrhythmia syndrome and provide resting QT assessment over time. However, QTc interval comparison at peak heart rates remains variable, and may be limited by the single ‐lead ECG vector when using the patch monitor. Apart from QTc intervals at peak HR, patch monitors demonstrated good correlation with the ECG and Holter monitor for other parameters.This article is protected by copyright. All rights reserved. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - January 29, 2021 Category: Cardiology Authors: Christopher C. Cheung, Brianna Davies, Karen Gibbs, Zachary W. Laksman, Andrew D. Krahn Tags: BRIEF COMMUNICATION Source Type: research